Query 'Hydrophobic cleft formed by subdomains 1 and 3' matched 33 Records
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Record No : 1 |
| Instance ID | 10081 | | Regular Expression | [IL]xx[^P][^P][^P][^P]Rxxxxx[IL]xx[^P][^P][ILV][ILM] | | Motif Instance | LRRKGRNRSDRASLVTMHIL | | Bait Uniprot Accession | Q8VIM5 | | Bait Uniprot Identifier | MYCD_MOUSE | | Bait Gene Name | Myocd | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 64-83 | | Critical Residues | P8 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Fluorescence polarization spectroscopy; GFP tag; Pull down; Alanine scanning | | Interaction ID | 20081 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18025109 | | Comments | RPEL motif (64-83) in mouse Myocardin that binds to the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 2 |
| Instance ID | 10082 | | Regular Expression | [IL]xx[^P][^P][^P][^P]Rxxxxx[IL]xx[^P][^P][ILV][ILM] | | Motif Instance | LNEKIAQRPGPMELVEKNIL | | Bait Uniprot Accession | Q9ULH7 | | Bait Uniprot Identifier | MKL2_HUMAN | | Bait Gene Name | MKL2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 130-149 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 20082 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14565952 | | Comments | RPEL motif (130-149) in human Myocardin-related transcription factor MKL2 that binds to the hydrophobic cleft formed by subdomains 1 and 3 of human Alpha-actin-2 |
Record No : 3 |
| Instance ID | 10083 | | Regular Expression | [IL]xx[^P][^P][^P][^P]Rxxxxx[IL]xx[^P][^P][ILV][ILM] | | Motif Instance | LNEKIALRPGPLELVEKNIL | | Bait Uniprot Accession | Q8VIM5 | | Bait Uniprot Identifier | MYCD_MOUSE | | Bait Gene Name | Myocd | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 108-127 | | Critical Residues | P8 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Fluorescence polarization spectroscopy; GFP tag; Pull down; Alanine scanning | | Interaction ID | 20083 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18025109 | | Comments | RPEL motif (108-127) in mouse Myocardin that binds to the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 4 |
| Instance ID | 10084 | | Regular Expression | [IL]xx[^P][^P][^P][^P]Rxxxxx[IL]xx[^P][^P][ILV][ILM] | | Motif Instance | LQLKLQQRRTREELVSQGIM | | Bait Uniprot Accession | Q8K4J6 | | Bait Uniprot Identifier | MKL1_MOUSE | | Bait Gene Name | Mkl1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 17-36 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Fluorescence polarization spectroscopy; GFP tag; Pull down; Alanine scanning; structure based prediction; Molecular sieving; circular dichroism; Co-IP; Colocalization; Sequence based prediction | | Interaction ID | 20084 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18025109, 21673315, 17588931, 12732141, 19008859 | | Comments | RPEL motif (17-36) in mouse Myocardin-related transcription factor Mkl1 that binds to the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 5 |
| Instance ID | 10085 | | Regular Expression | [IL]xx[^P][^P][^P][^P]Rxxxxx[IL]xx[^P][^P][ILV][ILM] | | Motif Instance | LKRKIRSRPERAELVRMHIL | | Bait Uniprot Accession | Q8K4J6 | | Bait Uniprot Identifier | MKL1_MOUSE | | Bait Gene Name | Mkl1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 61-80 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Fluorescence polarization spectroscopy; GFP tag; Pull down; Alanine scanning; structure based prediction; Molecular sieving; circular dichroism; Colocalization; Co-IP; Sequence based prediction | | Interaction ID | 20085 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18025109, 21673315, 20818336, 17588931, 12732141, 19008859 | | Comments | RPEL motif (61-80) in mouse Myocardin-related transcription factor Mkl1 that binds to the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 6 |
| Instance ID | 10086 | | Regular Expression | [IL]xx[^P][^P][^P][^P]Rxxxxx[IL]xx[^P][^P][ILV][ILM] | | Motif Instance | LNEKIAQRPGPMELVEKNIL | | Bait Uniprot Accession | Q8K4J6 | | Bait Uniprot Identifier | MKL1_MOUSE | | Bait Gene Name | Mkl1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 105-124 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Fluorescence polarization spectroscopy; GFP tag; Pull down; Alanine scanning; structure based prediction; Molecular sieving; circular dichroism; Co-IP; Colocalization; Sequence based prediction | | Interaction ID | 20086 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18025109, 21673315, 17588931, 12732141, 19008859 | | Comments | RPEL motif (105-124) in mouse Myocardin-related transcription factor Mkl1 that binds to the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 7 |
| Instance ID | 10087 | | Regular Expression | [IL]xx[^P][^P][^P][^P]Rxxxxx[IL]xx[^P][^P][ILV][ILM] | | Motif Instance | LQLRLQQRRTQEQLANQGLI | | Bait Uniprot Accession | Q8VIM5 | | Bait Uniprot Identifier | MYCD_MOUSE | | Bait Gene Name | Myocd | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 20-39 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Fluorescence polarization spectroscopy; GFP tag; Pull down; Alanine scanning | | Interaction ID | 20087 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18025109 | | Comments | RPEL motif (20-39) in mouse Myocardin that binds to the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 8 |
| Instance ID | 10088 | | Regular Expression | [R]xx[ILVMF][ILMVF][^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATI] | | Motif Instance | RDALLGDIRKGMKLKKA | | Bait Uniprot Accession | P37370 | | Bait Uniprot Identifier | VRP1_YEAST | | Bait Gene Name | VRP1 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 31-47 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Classical fluorescence spectroscopy; Y2H; Mutation analysis; GFP tag | | Interaction ID | 20088 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9412475 | | Comments | WH2 motif in Yeast verprolin, encoded by VRP1, that binds to the hydrophobic cleft formed by subdomains 1 and 3 of Yeast Actin, thus allowing Verprolin to serve as a polarity development protein, perhaps by anchoring actin |
Record No : 9 |
| Instance ID | 10089 | | Regular Expression | [R]xx[ILVMF][ILMVF][^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATI] | | Motif Instance | REQLMESIRKGKELKQI | | Bait Uniprot Accession | Q9U1K1 | | Bait Uniprot Identifier | SPIR_DROME | | Bait Gene Name | spir | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 464-480 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Sequence based prediction; Affinity chromatography technology; Electron microscopy; Pull down; Alanine scanning; NMR; Classical fluorescence spectroscopy; structure based prediction; Molecular sieving | | Interaction ID | 20089 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10556052, 15674283, 20538977 | | Comments | WH2 motif (464-480) in Drosophila protein Spire that binds to the hydrophobic cleft formed by subdomains 1 and 3 of Drosophila Actin-5C |
Record No : 10 |
| Instance ID | 10090 | | Regular Expression | [R]xx[ILVMF][ILMVF][^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATI] | | Motif Instance | REQLMESIRKGKELKQI | | Bait Uniprot Accession | Q9U1K1 | | Bait Uniprot Identifier | SPIR_DROME | | Bait Gene Name | spir | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 464-480 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Sequence based prediction; Affinity chromatography technology; Electron microscopy; Pull down; Alanine scanning; NMR; Classical fluorescence spectroscopy; structure based prediction; Molecular sieving | | Interaction ID | 20090 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10556052, 15674283, 20538977 | | Comments | WH2 motif (464-480) in Drosophila protein Spire that binds to the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 11 |
| Instance ID | 10091 | | Regular Expression | [R]xx[ILVMF][ILMVF][^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATI] | | Motif Instance | REQLMESIRKGKELKQI | | Bait Uniprot Accession | Q9U1K1 | | Bait Uniprot Identifier | SPIR_DROME | | Bait Gene Name | spir | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 464-480 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Sequence based prediction; Affinity chromatography technology; Electron microscopy; Pull down; Alanine scanning; NMR; Classical fluorescence spectroscopy; structure based prediction; Molecular sieving | | Interaction ID | 20091 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10556052, 15674283, 20538977 | | Comments | WH2 motif (464-480) in Drosophila protein Spire that binds to the hydrophobic cleft formed by subdomains 1 and 3 of chicken Alpha-actin-1 |
Record No : 12 |
| Instance ID | 10092 | | Regular Expression | [R]xx[ILVMF][ILMVF][^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATI] | | Motif Instance | REQLMESIRKGKELKQI | | Bait Uniprot Accession | Q9U1K1 | | Bait Uniprot Identifier | SPIR_DROME | | Bait Gene Name | spir | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 464-480 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Sequence based prediction; Affinity chromatography technology; Electron microscopy; Pull down; Alanine scanning; NMR; Classical fluorescence spectroscopy; structure based prediction; Molecular sieving | | Interaction ID | 20092 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10556052, 15674283, 20538977 | | Comments | WH2 motif (464-480) in Drosophila protein Spire that binds to the hydrophobic cleft formed by subdomains 1 and 3 of Acanthamoeba Actin-1 |
Record No : 13 |
| Instance ID | 10093 | | Regular Expression | [R]xx[ILVMF][ILMVF][^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATI] | | Motif Instance | RGALLDQIRQGIQLNKT | | Bait Uniprot Accession | P42768 | | Bait Uniprot Identifier | WASP_HUMAN | | Bait Gene Name | WAS | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 431-447 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Fluorescence polarization spectroscopy; ITC; circular dichroism; X-ray crystallography; structure based prediction; Sequence based prediction | | Interaction ID | 20093 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11146629, 16275905 | | Comments | WH2 motif in human Wiskott-Aldrich syndrome protein that binds to the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 14 |
| Instance ID | 10094 | | Regular Expression | [R]xx[ILVMF][ILMVF][^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATI] | | Motif Instance | RSVLLEAIRKGIQLRKV | | Bait Uniprot Accession | Q92558 | | Bait Uniprot Identifier | WASF1_HUMAN | | Bait Gene Name | WASF1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 498-514 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Fluorescence polarization spectroscopy; ITC; circular dichroism; NMR | | Interaction ID | 20094 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11146629, 16403731 | | Comments | WH2 motif in human protein WAVE-1 that binds to the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 15 |
| Instance ID | 10095 | | Regular Expression | [R]xx[ILVMF][ILMVF][^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATI] | | Motif Instance | RSVLLEAIRKGIQLRKV | | Bait Uniprot Accession | Q92558 | | Bait Uniprot Identifier | WASF1_HUMAN | | Bait Gene Name | WASF1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 498-514 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Fluorescence polarization spectroscopy; ITC; circular dichroism; NMR | | Interaction ID | 20095 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11146629, 16403731 | | Comments | WH2 motif in human protein WAVE-1 that binds to the hydrophobic cleft formed by subdomains 1 and 3 of Acanthamoeba Actin-1 |
Record No : 16 |
| Instance ID | 10096 | | Regular Expression | [R]xx[ILVMF][ILMVF][^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATI] | | Motif Instance | RNALLSDISKGKKLKKT | | Bait Uniprot Accession | O43516 | | Bait Uniprot Identifier | WIPF1_HUMAN | | Bait Gene Name | WIPF1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 33-49 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography; ITC; structure based prediction; Sequence based prediction | | Interaction ID | 20096 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16275905 | | Comments | WH2 motif in human WASP-interacting protein that binds to the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 17 |
| Instance ID | 10097 | | Regular Expression | [R]xx[ILVMF][ILMVF][^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATI] | | Motif Instance | RSDLLSAIRQGFQLRRV | | Bait Uniprot Accession | Q9Y6W5 | | Bait Uniprot Identifier | WASF2_HUMAN | | Bait Gene Name | WASF2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 437-453 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography; ITC; structure based prediction; Sequence based prediction | | Interaction ID | 20097 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16275905 | | Comments | WH2 motif in human protein WAVE-2 that binds to the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 18 |
| Instance ID | 10098 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | NPELQSAIGQGAALKHA | | Bait Uniprot Accession | P18281 | | Bait Uniprot Identifier | ACTO_ACACA | | Bait Gene Name | Not Available | | Bait Organism | Acanthamoeba castellanii (Amoeba) | | Sequence Position | 2-18 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Cross linking studies | | Interaction ID | 20098 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 1464307 | | Comments | The actin binding site of Acanthamoeba protein Actobindin that mediates its interaction with the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 19 |
| Instance ID | 10099 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | KNQFIAGIENFDAKKLKHT | | Bait Uniprot Accession | O97428 | | Bait Uniprot Identifier | O97428_DROME | | Bait Gene Name | cib | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 91-109 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Subcellular preparation; Cross linking studies; ITC; Structure based prediction; Sequence based prediction; X-ray crystallography | | Interaction ID | 20099 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11030623, 16275905 | | Comments | The WH2 motif (91-109) in Drosophila ciboulot that mediates its interaction with the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 20 |
| Instance ID | 10100 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | QQSIFEGITAFNQNNLKHT | | Bait Uniprot Accession | O97428 | | Bait Uniprot Identifier | O97428_DROME | | Bait Gene Name | cib | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 53-71 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Subcellular preparation; Cross linking studies; ITC; Structure based prediction; Sequence based prediction; X-ray crystallography | | Interaction ID | 20100 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11030623, 16275905 | | Comments | The WH2 motif (53-71) in Drosophila ciboulot that mediates its interaction with the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 21 |
| Instance ID | 10101 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | DKPDMAEIEKFDKSKLKKT | | Bait Uniprot Accession | P20065 | | Bait Uniprot Identifier | TYB4_MOUSE | | Bait Gene Name | Tmsb4x | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 9-27 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Cross linking studies | | Interaction ID | 20101 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 1464307 | | Comments | The WH2 motif in mouse Thymosin beta-4 that mediates its interaction with the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 22 |
| Instance ID | 10102 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | HAMILEFIRSRPPLKKA | | Bait Uniprot Accession | Q9U1K1 | | Bait Uniprot Identifier | SPIR_DROME | | Bait Gene Name | spir | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 432-448 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Affinity chromatography technology; Mutation analysis; Electron microscopy; Pull down; Alanine scanning | | Interaction ID | 20102 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15674283 | | Comments | WH2 motif (432-448) in Drosophila protein Spire that binds to the hydrophobic cleft formed by subdomains 1 and 3 of Acanthamoeba Actin-1 |
Record No : 23 |
| Instance ID | 10103 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | YEILMGDIRAKKYQLRKV | | Bait Uniprot Accession | Q9U1K1 | | Bait Uniprot Identifier | SPIR_DROME | | Bait Gene Name | spir | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 400-417 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Sequence based prediction; Affinity chromatography technology; Electron microscopy; Pull down; Alanine scanning; Classical fluorescence spectroscopy; structure based prediction; Molecular sieving; NMR | | Interaction ID | 20103 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10556052, 15674283, 20538977 | | Comments | WH2 motif (400-417) in Drosophila protein Spire that binds to the hydrophobic cleft formed by subdomains 1 and 3 of Drosophila Actin-5C |
Record No : 24 |
| Instance ID | 10104 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | YEILMGDIRAKKYQLRKV | | Bait Uniprot Accession | Q9U1K1 | | Bait Uniprot Identifier | SPIR_DROME | | Bait Gene Name | spir | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 400-417 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Sequence based prediction; Affinity chromatography technology; Electron microscopy; Pull down; Alanine scanning; Classical fluorescence spectroscopy; structure based prediction; Molecular sieving; NMR | | Interaction ID | 20104 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10556052, 15674283, 20538977 | | Comments | WH2 motif (400-417) in Drosophila protein Spire that binds to the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 25 |
| Instance ID | 10105 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | YEILMGDIRAKKYQLRKV | | Bait Uniprot Accession | Q9U1K1 | | Bait Uniprot Identifier | SPIR_DROME | | Bait Gene Name | spir | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 400-417 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Sequence based prediction; Affinity chromatography technology; Electron microscopy; Pull down; Alanine scanning; Classical fluorescence spectroscopy; structure based prediction; Molecular sieving; NMR | | Interaction ID | 20105 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10556052, 15674283, 20538977 | | Comments | WH2 motif (400-417) in Drosophila protein Spire that binds to the hydrophobic cleft formed by subdomains 1 and 3 of chicken Alpha-actin-1 |
Record No : 26 |
| Instance ID | 10106 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | YEILMGDIRAKKYQLRKV | | Bait Uniprot Accession | Q9U1K1 | | Bait Uniprot Identifier | SPIR_DROME | | Bait Gene Name | spir | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 400-417 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Sequence based prediction; Affinity chromatography technology; Electron microscopy; Pull down; Alanine scanning; Classical fluorescence spectroscopy; structure based prediction; Molecular sieving; NMR | | Interaction ID | 20106 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10556052, 15674283, 20538977 | | Comments | WH2 motif (400-417) in Drosophila protein Spire that binds to the hydrophobic cleft formed by subdomains 1 and 3 of Acanthamoeba Actin-1 |
Record No : 27 |
| Instance ID | 10107 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | WVQVIDELRRGVRLKKS | | Bait Uniprot Accession | Q9U1K1 | | Bait Uniprot Identifier | SPIR_DROME | | Bait Gene Name | spir | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 370-386 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Affinity chromatography technology; Mutation analysis; Electron microscopy; Pull down; Alanine scanning | | Interaction ID | 20107 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15674283 | | Comments | WH2 motif (370-386) in Drosophila protein Spire that binds to the hydrophobic cleft formed by subdomains 1 and 3 of Acanthamoeba Actin-1 |
Record No : 28 |
| Instance ID | 10108 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | AGDFLHQIRTKQFNLRRV | | Bait Uniprot Accession | Q6AWX6 | | Bait Uniprot Identifier | SCAR1_ARATH | | Bait Gene Name | SCAR1 | | Bait Organism | Arabidopsis thaliana (Mouse-ear cress) | | Sequence Position | 757-774 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Western blot; Pull down; Sequence based prediction | | Interaction ID | 20108 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 1529676, 15534215 | | Comments | The WH2 motif in Arabidopsis protein SCAR1 that mediates its interaction with the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 29 |
| Instance ID | 10109 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | KDSLLAQIRNKSVNLKPA | | Bait Uniprot Accession | Q5XPJ9 | | Bait Uniprot Identifier | SCAR2_ARATH | | Bait Gene Name | SCAR2 | | Bait Organism | Arabidopsis thaliana (Mouse-ear cress) | | Sequence Position | 1336-1353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 20109 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15534215 | | Comments | The WH2 motif in Arabidopsis protein SCAR2 that mediates its interaction with the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 30 |
| Instance ID | 10110 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | NDSLLEIIRSKSFNLRPA | | Bait Uniprot Accession | Q5XPJ6 | | Bait Uniprot Identifier | SCAR4_ARATH | | Bait Gene Name | SCAR4 | | Bait Organism | Arabidopsis thaliana (Mouse-ear cress) | | Sequence Position | 1106-1123 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down; Sequence based prediction | | Interaction ID | 20110 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15534215 | | Comments | The WH2 motif in Arabidopsis protein SCAR4 that mediates its interaction with the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 31 |
| Instance ID | 10111 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | GEDMLNAIRRGVKLKKT | | Bait Uniprot Accession | O43312 | | Bait Uniprot Identifier | MTSS1_HUMAN | | Bait Gene Name | MTSS1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 728-744 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Structure based prediction; ITC; Sequence based prediction; X-ray crystallography | | Interaction ID | 20111 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17292833, 16275905 | | Comments | The WH2 motif in human Metastasis suppressor protein 1 that mediates its interaction with the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 32 |
| Instance ID | 10112 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | DKPDMAEIEKFDKSKLKKT | | Bait Uniprot Accession | A2VCK8 | | Bait Uniprot Identifier | A2VCK8_HUMAN | | Bait Gene Name | TMSB4X | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 3-21 | | Critical Residues | P17; P18 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | ITC; structure based prediction; Sequence based prediction; X-ray crystallography; Mutation analysis; Cross linking studies; circular dichroism | | Interaction ID | 20112 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16275905, 8617195 | | Comments | The WH2 motif in human Thymosin beta 4 that mediates its interaction with the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
Record No : 33 |
| Instance ID | 10113 | | Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] | | Motif Instance | TGDFLQQIRTQQFNLRPV | | Bait Uniprot Accession | Q9LP46 | | Bait Uniprot Identifier | SCAR3_ARATH | | Bait Gene Name | SCAR3 | | Bait Organism | Arabidopsis thaliana (Mouse-ear cress) | | Sequence Position | 955-972 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down; Sequence based prediction | | Interaction ID | 20113 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15534215 | | Comments | The WH2 motif in Arabidopsis protein SCAR3 that mediates its interaction with the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
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