BROWSE RESULT OF A

166 Records

 

Record No:1


ACCESS NO100007
GENEANXA5
DESCRIPTIONAnnexin A5
NCBI ENTREZ ACCESS NO308
UNIPROT ACCESS NOP08758
ORGANISMHuman
DISEASE PHENOTYPEAsthma ( comparison between high and low socio-economic conditions [SEC])
SAMPLECD2+ cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSIt is involved in stress and wound response.
GEO_PRIDE_ACCESS_NOGSE7894
REFERENCE19001005
DRUG TARGETBE0004149
MONCLONAL ANTIBODYAnti-Annexin V for Human


Record No:2


ACCESS NO100009
GENEADM
DESCRIPTIONAdrenomedullin
NCBI ENTREZ ACCESS NO133
UNIPROT ACCESS NOP35318
ORGANISMHuman
DISEASE PHENOTYPEAsthma ( comparison between high and low socio-economic conditions [SEC])
SAMPLECD2+ cells
TECHNIQUESMicroarray and TaqMan Gene Expression Assays
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is involved in wound responsee.
GEO_PRIDE_ACCESS_NOGSE7894
REFERENCE19001005
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:3


ACCESS NO100038
GENEANK3
DESCRIPTIONAnkyrin 3
NCBI ENTREZ ACCESS NO288
UNIPROT ACCESS NOQ12955
ORGANISMHuman
DISEASE PHENOTYPEAsthma ( comparison between high and low socio-economic conditions [SEC])
SAMPLECD2+ cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene is upregulated more in high SEC group.
GEO_PRIDE_ACCESS_NOGSE7894
REFERENCE19001005
DRUG TARGET
MONCLONAL ANTIBODYAnti-Ankyrin G for Mouse/Rat/Human


Record No:4


ACCESS NO100053
GENEALOX15B
DESCRIPTIONArachidonate 15-lipoxygenase type B
NCBI ENTREZ ACCESS NO247
UNIPROT ACCESS NOO15296
ORGANISMHuman
DISEASE PHENOTYPEAcute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESMicroarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is involved in arachidonic acid/prostagandin metabolism.
GEO_PRIDE_ACCESS_NOGSE16032
REFERENCE19620293
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:5


ACCESS NO100054
GENEALOX5
DESCRIPTIONArachidonate 5-lipoxygenase
NCBI ENTREZ ACCESS NO240
UNIPROT ACCESS NOP09917
ORGANISMHuman
DISEASE PHENOTYPEAcute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESMicroarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is involved in arachidonic acid/prostagandin metabolism.
GEO_PRIDE_ACCESS_NOGSE16032
REFERENCE19620293
DRUG TARGET
MONCLONAL ANTIBODYAnti-5 Lipoxygenase for Mouse/Rat/Human


Record No:6


ACCESS NO100080
GENEADORA3
DESCRIPTIONAdenosine A3 receptor
NCBI ENTREZ ACCESS NO140
UNIPROT ACCESS NOQ6P2N6
ORGANISMHuman
DISEASE PHENOTYPEAcute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESMicroarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is involved in innate immunity.
GEO_PRIDE_ACCESS_NOGSE16032
REFERENCE19620293
DRUG TARGETBE0000354
MONCLONAL ANTIBODYN/A


Record No:7


ACCESS NO100084
GENEAREG
DESCRIPTIONAmphiregulin
NCBI ENTREZ ACCESS NO374
UNIPROT ACCESS NOP15514
ORGANISMHuman
DISEASE PHENOTYPEAcute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESMicroarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is involved in adaptive immunity.
GEO_PRIDE_ACCESS_NOGSE16032
REFERENCE19620293
DRUG TARGET
MONCLONAL ANTIBODYAnti-Amphiregulin for Human


Record No:8


ACCESS NO100096
GENEADAMTS2
DESCRIPTIONADAM metallopeptidase with thrombospondin type 1 motif-2
NCBI ENTREZ ACCESS NO9509
UNIPROT ACCESS NOO95450
ORGANISMHuman
DISEASE PHENOTYPEAcute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESMicroarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSThis gene is associated with inflammation.
GEO_PRIDE_ACCESS_NOGSE16032
REFERENCE19620293
DRUG TARGET
MONCLONAL ANTIBODYAnti-ADAMTS2 for Rat/Human


Record No:9


ACCESS NO100113
GENEArg1
DESCRIPTIONArginase 1
NCBI ENTREZ ACCESS NO11846
UNIPROT ACCESS NOQ61176
ORGANISMMouse
DISEASE PHENOTYPEAllergic asthma and the role of IL-4 and IL-13
SAMPLELung tissue
TECHNIQUESDNA Affymetrix microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis arginine metabolism is commonly induced by allergens and Th2 cytokines such as IL-4 and IL-13.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19249085
DRUG TARGETBE0000286
MONCLONAL ANTIBODYAnti-liver Arginase for Human


Record No:10


ACCESS NO100121
GENEAdam8
DESCRIPTIONA disintegrin and metalloprotease domain 8
NCBI ENTREZ ACCESS NO11501
UNIPROT ACCESS NOQ05910
ORGANISMMouse
DISEASE PHENOTYPEAllergic asthma and the role of IL-4 and IL-13
SAMPLELung tissue
TECHNIQUESDNA Affymetrix microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis protease is specifically induced by Th2 cytokines such as IL-4 and IL-13.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19249085
DRUG TARGET
MONCLONAL ANTIBODYAnti-ADAM8 [EPR14612] for Mouse/Rat/Human


Record No:11


ACCESS NO100125
GENEAtf3
DESCRIPTIONActivating transcription factor 3
NCBI ENTREZ ACCESS NO11910
UNIPROT ACCESS NOQ60765
ORGANISMMouse
DISEASE PHENOTYPEAllergic asthma and the role of IL-4 and IL-13
SAMPLELung tissue
TECHNIQUESDNA Affymetrix microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is an IL-4 specific host immune responsive gene induced in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19249085
DRUG TARGET
MONCLONAL ANTIBODYAnti-ATF3 for Human


Record No:12


ACCESS NO100140
GENEAgr2
DESCRIPTIONAnterior gradient 2
NCBI ENTREZ ACCESS NO23795
UNIPROT ACCESS NOO88312
ORGANISMMouse
DISEASE PHENOTYPEAllergic asthma and the role of IL-4 and IL-13
SAMPLELung tissue
TECHNIQUESDNA Affymetrix microarray
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSThis is an IL-13 specific epithelial product induced in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19249085
DRUG TARGET
MONCLONAL ANTIBODYAnti-AGR2 + AGR3 for Human


Record No:13


ACCESS NO100142
GENEAass
DESCRIPTIONAminoadipate-semialdehyde synthase
NCBI ENTREZ ACCESS NO30956
UNIPROT ACCESS NOQ99K67
ORGANISMMouse
DISEASE PHENOTYPEAllergic asthma and the role of IL-4 and IL-13
SAMPLELung tissue
TECHNIQUESDNA Affymetrix microarray
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSThis is an IL-13 specific lysine metabolism gene induced in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19249085
DRUG TARGET
MONCLONAL ANTIBODYAnti-AASS for Mouse/Human


Record No:14


ACCESS NO100158
GENEAREG
DESCRIPTIONAmphiregulin
NCBI ENTREZ ACCESS NO374
UNIPROT ACCESS NOP15514
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is a cell communication protein significantly upregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYAnti-Amphiregulin for Human


Record No:15


ACCESS NO100174
GENEASB9
DESCRIPTIONAnkyrin repeat and SOCS box-containing 9
NCBI ENTREZ ACCESS NO140462
UNIPROT ACCESS NOQ96DX5
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is a cell communication protein significantly down regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:16


ACCESS NO100202
GENEADAM8
DESCRIPTIONA disintegrin and metalloproteinase domain 8
NCBI ENTREZ ACCESS NO101
UNIPROT ACCESS NOP78325
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene codes for a metabolic enzyme significantly up regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYAnti-ADAM8 [EPR14612] for Mouse/Rat/Human


Record No:17


ACCESS NO100205
GENEABCC3
DESCRIPTIONATP-binding cassette sub-family C member 3
NCBI ENTREZ ACCESS NO8714
UNIPROT ACCESS NOO15438
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene codes for a metabolic enzyme significantly up regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGETBE0001061
MONCLONAL ANTIBODYN/A


Record No:18


ACCESS NO100207
GENEATP2C2 (KIAA0703)
DESCRIPTIONProbable calcium-transporting ATPase KIAA0703
NCBI ENTREZ ACCESS NO9914
UNIPROT ACCESS NOO75185
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene codes for a metabolic enzyme significantly up regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:19


ACCESS NO100210
GENEAKR1C3
DESCRIPTIONAldo-keto reductase family 1 - member C3
NCBI ENTREZ ACCESS NO8644
UNIPROT ACCESS NOP42330
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene codes for a metabolic enzyme significantly down regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGETBE0000592
MONCLONAL ANTIBODYAnti-AKR1C3 for Human


Record No:20


ACCESS NO100212
GENEALPP
DESCRIPTIONAlkaline phosphatase placental type precursor
NCBI ENTREZ ACCESS NO250
UNIPROT ACCESS NOP05187
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene codes for a metabolic enzyme significantly down regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGETBE0000314
MONCLONAL ANTIBODYAnti-ALPPL2 for Human


Record No:21


ACCESS NO100232
GENEARRDC3
DESCRIPTIONArrestin domain containing 3
NCBI ENTREZ ACCESS NO57561
UNIPROT ACCESS NOQ96B67
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene is significantly up regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:22


ACCESS NO100235
GENEAPBB1
DESCRIPTIONAmyloid beta (A4) precursor protein-binding B1
NCBI ENTREZ ACCESS NO322
UNIPROT ACCESS NOO00213
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene is significantly up regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:23


ACCESS NO100240
GENEAPCDD1
DESCRIPTIONAdenomatosis polyposis coli down-regulated 1
NCBI ENTREZ ACCESS NO147495
UNIPROT ACCESS NOQ8J025
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene is significantly down regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:24


ACCESS NO100274
GENEADAM19
DESCRIPTIONADAM metallopeptidase domain 19
NCBI ENTREZ ACCESS NO8728
UNIPROT ACCESS NOQ9H013
ORGANISMHuman
DISEASE PHENOTYPEAsthma exacerbation after rhinovirus infection
SAMPLEPrimary bronchial epithelial cells
TECHNIQUESAffymetrix GeneChip Microarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is expressed at higher levels in the asthma samples (P<0.05) and was downregulated by HRV in both groups. It is involved in cell-matrix interactions.
GEO_PRIDE_ACCESS_NOGSE13396
REFERENCE19710636
DRUG TARGET
MONCLONAL ANTIBODYAnti-SPARC for Rat/Human


Record No:25


ACCESS NO100304
GENEAcvr1
DESCRIPTIONActivin receptor type I
NCBI ENTREZ ACCESS NO11477
UNIPROT ACCESS NOP37172
ORGANISMMouse
DISEASE PHENOTYPEAsthma induced by Aspergillus fumigatus allergens
SAMPLEPeripheral blood monocytes
TECHNIQUESDNA Microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is a cytokine receptor. It has been observed to be down regulated in the present study.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20840155
DRUG TARGETBE0000264
MONCLONAL ANTIBODYAnti-Activin Receptor Type IA for Mouse/Rat/Human


Record No:26


ACCESS NO100322
GENEAgrn
DESCRIPTIONAgrin
NCBI ENTREZ ACCESS NO25592
UNIPROT ACCESS NON/A
ORGANISMRat
DISEASE PHENOTYPEEarly airway response (EAR) phase of asthma
SAMPLELung tissue
TECHNIQUESSerial analysis of gene expression (SAGE)
OMICSGenomics
STUDY High Throughput
COMMENTSThe expression of agrin was decreased in the SAGE library from asthmatic lung. This suggests that agrin may disperse the aggregation of molecules in the immunological synapse including the T-cell receptor and IgE receptor.
GEO_PRIDE_ACCESS_NOGSE2475
REFERENCE18922145
DRUG TARGET
MONCLONAL ANTIBODYAnti-Agrin for Mouse/Rat


Record No:27


ACCESS NO100341
GENEApoe
DESCRIPTIONApolipoprotein E
NCBI ENTREZ ACCESS NO11816
UNIPROT ACCESS NOP08226
ORGANISMMouse
DISEASE PHENOTYPEAsthma induced chemicals
SAMPLESerum
TECHNIQUES2D DIGE and MALDI-TOF-MS
OMICSProteomics
STUDY High Throughput
COMMENTSIt contributes to the protection against oxidative damage.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20860378
DRUG TARGETBE0001119
MONCLONAL ANTIBODYAnti-Calreticulin [FMC 75] for Mouse/Rat/Human/Monkey


Record No:28


ACCESS NO100352
GENEALDH3B1
DESCRIPTIONB1-transcript variant 2
NCBI ENTREZ ACCESS NO221
UNIPROT ACCESS NOP43353
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESIllumina Human Ref8 BeadChip arrays
OMICSGenomics
STUDY High Throughput
COMMENTSIt is upregulated in asthma exacerbation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19187333
DRUG TARGETBE0000446
MONCLONAL ANTIBODYN/A


Record No:29


ACCESS NO100389
GENEAlb
DESCRIPTIONSerum albumin
NCBI ENTREZ ACCESS NO11657
UNIPROT ACCESS NOP07724
ORGANISMMouse
DISEASE PHENOTYPEAsthma exacerbation and role of ambient particulate matter
SAMPLEBroncho Alveolar Lavage (BAL)F
TECHNIQUES2D PAGE andLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis gene is upregulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20029843
DRUG TARGETBE0000530
MONCLONAL ANTIBODYAnti-Human Serum Albumin antibody for Human


Record No:30


ACCESS NO100392
GENEArl2
DESCRIPTIONADP-ribosylation factor-like protein 2
NCBI ENTREZ ACCESS NO56327
UNIPROT ACCESS NOQ9D0J4
ORGANISMMouse
DISEASE PHENOTYPEAllergen induced asthma
SAMPLEBroncho Alveolar Lavage (BAL)F
TECHNIQUES2D PAGE and MALDI-TOF-MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis gene is upregulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15378764
DRUG TARGET
MONCLONAL ANTIBODYAnti-ARL2 for Mouse/Rat/Human


Record No:31


ACCESS NO100395
GENEAnxa1
DESCRIPTIONAnnexin-1
NCBI ENTREZ ACCESS NO16952
UNIPROT ACCESS NOP10107
ORGANISMMouse
DISEASE PHENOTYPEAllergen induced asthma
SAMPLEBroncho Alveolar Lavage (BAL)F
TECHNIQUES2D PAGE and MALDI-TOF-MS followed by immunoblot an
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSIt inhibits cytosolic phospholipase A2 (cPLA2) but in allergic asthma it undergoes proteolytic degradation. Its downregulation in 2D PAGE was not significant. However I western blot and real time PCR it showed significant downregulation as a result of degradation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15378764
DRUG TARGETBE0000422
MONCLONAL ANTIBODYAnti-Annexin A1 for Human


Record No:32


ACCESS NO100418
GENEATP5H
DESCRIPTIONATP synthase- H+ transporting- mitochondrial F0 complex subunit d isoform a
NCBI ENTREZ ACCESS NO10476
UNIPROT ACCESS NOO75947
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEbronchial epithelial cells stimulated with TGF bet
TECHNIQUES2D PAGE and MALDI-TOF-MS
OMICSProteomics
STUDY High Throughput
COMMENTSIt is upregulated in asthma inflammation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20219718
DRUG TARGET
MONCLONAL ANTIBODYAnti-ATP5H for Mouse/Rat/Human


Record No:33


ACCESS NO100449
GENEANXA3
DESCRIPTIONAnnexin A3
NCBI ENTREZ ACCESS NO306
UNIPROT ACCESS NOP12429
ORGANISMHuman
DISEASE PHENOTYPESevere asthma
SAMPLECD8 + T cells
TECHNIQUESMicroarray and Real time Q-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is upregulated in asthma inflammation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21917308
DRUG TARGETBE0003201
MONCLONAL ANTIBODYAnti-Annexin A3 for Human


Record No:34


ACCESS NO100464
GENEAXIN2
DESCRIPTIONAxin 2
NCBI ENTREZ ACCESS NO8313
UNIPROT ACCESS NOQ9Y2T1
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEAirway smooth muscle cell (ASM) line
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is induced in airway smooth muscle cell after glucocorticoid treatment.
GEO_PRIDE_ACCESS_NOGSE3946
REFERENCE21257922
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:35


ACCESS NO100479
GENEARG1
DESCRIPTIONArginase-1
NCBI ENTREZ ACCESS NO383
UNIPROT ACCESS NOP05089
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis and eczema
SAMPLESkin tapings
TECHNIQUESnano-HPLC-MS/MS (ion trap)
OMICSProteomics
STUDY High Throughput
COMMENTSIt produces urea from L-arginine. Urea is a hygroscopic component of the natural moisturizing factor of human skin. This gene is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient without eczema herpeticum .
GEO_PRIDE_ACCESS_NON/A
REFERENCE21211653
DRUG TARGETBE0000286
MONCLONAL ANTIBODYAnti-liver Arginase for Mouse


Record No:36


ACCESS NO100488
GENEALB
DESCRIPTIONAlbumin
NCBI ENTREZ ACCESS NO213
UNIPROT ACCESS NOP02768
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis
SAMPLENasal fluid
TECHNIQUESLC-MS/MS and ELISA
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSThis protein is identified as s potential markers for treatment response to Glucocorticoids in allergic rhinitis. It is a component of acute phase response pathway. Its expression decrease following GC treatment as estimated in LC-MS/MS but not significantly in ELISA assay.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21887273
DRUG TARGETBE0000530
MONCLONAL ANTIBODYN/A


Record No:37


ACCESS NO100489
GENEA2M
DESCRIPTIONalpha-2-macroglobulin
NCBI ENTREZ ACCESS NO2
UNIPROT ACCESS NOP01023
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of glucocorticoid treatment
SAMPLEBronchial biopsy
TECHNIQUESiTRAQ labelling followed by nano LC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSIt is a type of cytokione present in extracellular space.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21939520
DRUG TARGETBE0000910
MONCLONAL ANTIBODYAnti-alpha 2 Macroglobulin for Human


Record No:38


ACCESS NO100490
GENEALDOA
DESCRIPTIONaldolase A fructose-bisphosphate
NCBI ENTREZ ACCESS NO226
UNIPROT ACCESS NOP04075
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of glucocorticoid treatment
SAMPLEBronchial biopsy
TECHNIQUESiTRAQ labelling followed by nano LC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis gene shows down regulation of protein expression after budesonide treatment on asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21939520
DRUG TARGETBE0001683
MONCLONAL ANTIBODYAnti-Aldolase for Human


Record No:39


ACCESS NO100491
GENEATP5B
DESCRIPTIONATP synthase H+ transporting mitochondrial F1 complex-beta polypeptide
NCBI ENTREZ ACCESS NO506
UNIPROT ACCESS NOP06576
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of glucocorticoid treatment
SAMPLEBronchial biopsy
TECHNIQUESiTRAQ labelling followed by nano LC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis gene shows down regulation of protein expression after budesonide treatment on asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21939520
DRUG TARGETBE0003841
MONCLONAL ANTIBODYAnti-ATPB [3D5] for Mouse/Rat/Human


Record No:40


ACCESS NO100496
GENEANXA5
DESCRIPTIONAnnexin A5
NCBI ENTREZ ACCESS NO308
UNIPROT ACCESS NOP08758
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of glucocorticoid treatment
SAMPLEBronchial biopsy
TECHNIQUESiTRAQ labelling followed by nano LC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is involved in fibrosis and inflammation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21939520
DRUG TARGETBE0004149
MONCLONAL ANTIBODYAnti-Annexin V for Human


Record No:41


ACCESS NO100527
GENEARG1
DESCRIPTIONArginase 1
NCBI ENTREZ ACCESS NO11846
UNIPROT ACCESS NOQ61176
ORGANISMMouse
DISEASE PHENOTYPEAsthma
SAMPLEMacrophages from Broncho Alveolar Lavage (BAL) and
TECHNIQUESIllumina gene chip microarray and real time PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is produced by the M2 macrophages present in the airway lumen. This protein along with chitinases and other chemokines may play an important role in leukocyte migration into asthmatic airways.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23685352
DRUG TARGETBE0000286
MONCLONAL ANTIBODYN/A


Record No:42


ACCESS NO100534
GENEAdam8
DESCRIPTIONADAM metallopeptidase domain 8
NCBI ENTREZ ACCESS NO11501
UNIPROT ACCESS NOQ05910
ORGANISMMouse
DISEASE PHENOTYPEAcute and chronic asthma
SAMPLETissue from left lung
TECHNIQUESAffymetrix gene chip cDNA microarray
OMICSGenomics
STUDY High Throughput
COMMENTS
GEO_PRIDE_ACCESS_NON/A
REFERENCE18087161
DRUG TARGET
MONCLONAL ANTIBODYAnti-ADAM8 for Human


Record No:43


ACCESS NO100547
GENEAlox15
DESCRIPTIONArachidonate 15-lipoxygenase
NCBI ENTREZ ACCESS NO11687
UNIPROT ACCESS NOP39654
ORGANISMMouse
DISEASE PHENOTYPEAsthma
SAMPLETissue from bronchial biopsy
TECHNIQUESMicroarray-Affymetrix HG-U95Av2 GeneChips
OMICSGenomics
STUDY High Throughput
COMMENTSIt s new potential candidate of asthma pathogenesis.
GEO_PRIDE_ACCESS_NOGSE15823
REFERENCE15038835
DRUG TARGETBE0000309
MONCLONAL ANTIBODYAnti-15 Lipoxygenase 1 for Human/Rat/Monkey


Record No:44


ACCESS NO100553
GENEAatf (Trb)
DESCRIPTIONT cell receptor beta locus 
NCBI ENTREZ ACCESS NO56321
UNIPROT ACCESS NOQ9JKX4
ORGANISMMouse
DISEASE PHENOTYPEAsthma
SAMPLETissue from bronchial biopsy
TECHNIQUESMicroarray-Affymetrix HG-U95Av2 GeneChips
OMICSGenomics
STUDY High Throughput
COMMENTSdownregulated in allergic asthma.
GEO_PRIDE_ACCESS_NOGSE15823
REFERENCE15038835
DRUG TARGET
MONCLONAL ANTIBODYAnti-AATF for Human


Record No:45


ACCESS NO100600
GENEAPOB
DESCRIPTIONApolipoprotein B
NCBI ENTREZ ACCESS NO338
UNIPROT ACCESS NOP04114
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEBroncho Alveolar Lavage (BAL)F
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSUpregulated after allergen challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-APOBEC for Mouse/Rat/Human


Record No:46


ACCESS NO100601
GENEAPOA1
DESCRIPTIONApolipoprotein A-I
NCBI ENTREZ ACCESS NO335
UNIPROT ACCESS NOP02647
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEBroncho Alveolar Lavage (BAL)F
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSUpregulated after allergen challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-Apolipoprotein A1 for Human


Record No:47


ACCESS NO100606
GENEACE
DESCRIPTIONAngiotensinogen
NCBI ENTREZ ACCESS NO1636
UNIPROT ACCESS NOP12821
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEBroncho Alveolar Lavage (BAL)F
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSIt is a serum protein and upregulated after allergen challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0000221
MONCLONAL ANTIBODYAnti-Angiotensin converting enzyme 1 for Human/Mouse/Rat


Record No:48


ACCESS NO100612
GENEACSL3
DESCRIPTIONacyl-CoA synthetase long-chain family member 3
NCBI ENTREZ ACCESS NO2181
UNIPROT ACCESS NOO95573
ORGANISMHuman
DISEASE PHENOTYPEChildhood asthma
SAMPLEUmbilical cord white blood cells
TECHNIQUESMethylation specific PCR
OMICSEpigenetics
STUDY Low Throughput
COMMENTSMethylation of the ACSL3 5'-CGI is significantly associated with asthma in children.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19221603
DRUG TARGETBE0001093
MONCLONAL ANTIBODYN/A


Record No:49


ACCESS NO100620
GENEARG1
DESCRIPTIONArginase 1
NCBI ENTREZ ACCESS NO383
UNIPROT ACCESS NOP05089
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEBuccal mucosal cells
TECHNIQUESPyrosequencing
OMICSEpigenetics
STUDY Low Throughput
COMMENTSDNA methylation at the promoter of Arg1 is associated with exhaled nitric oxide- a well known biomarker of airway inflammation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21512169
DRUG TARGETBE0000286
MONCLONAL ANTIBODYN/A


Record No:50


ACCESS NO100621
GENEARG2
DESCRIPTIONArginase 2
NCBI ENTREZ ACCESS NO384
UNIPROT ACCESS NOP78540
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEBuccal mucosal cells
TECHNIQUESPyrosequencing
OMICSEpigenetics
STUDY Low Throughput
COMMENTSDifference in DNA methylation at the promoter of Arg1 controls the exhaled nitric oxide.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21512169
DRUG TARGETBE0000758
MONCLONAL ANTIBODYAnti-ARG2 for Human/Rat


Record No:51


ACCESS NO100622
GENEALOX12
DESCRIPTIONarachidonate 12-lipoxygenase
NCBI ENTREZ ACCESS NO239
UNIPROT ACCESS NOP18054
ORGANISMHuman
DISEASE PHENOTYPEChildhood asthma
SAMPLEcord blood DNA
TECHNIQUESPyrosequencing
OMICSEpigenetics
STUDY Low Throughput
COMMENTSHypomethylation at two CpGs of ALOX12 was significantly associated with persistent wheezing.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22920181
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:52


ACCESS NO100627
GENEAPOH
DESCRIPTIONApolipoprotein H
NCBI ENTREZ ACCESS NO350
UNIPROT ACCESS NOP02749
ORGANISMHuman
DISEASE PHENOTYPESeasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification)
SAMPLENasal fluid
TECHNIQUESQuantitative proteomic analysis through LC/MSMS an
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSPart of the acute phase response pathway and significantly decreased after Glucocorticoid treatment.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21887273
DRUG TARGETBE0002854
MONCLONAL ANTIBODYAnti-Apolipoprotein H for Rat/Human


Record No:53


ACCESS NO100629
GENEA2M
DESCRIPTIONAlpha-2-macroglobulin
NCBI ENTREZ ACCESS NO2
UNIPROT ACCESS NOP01023
ORGANISMHuman
DISEASE PHENOTYPESeasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification)
SAMPLENasal fluid
TECHNIQUESQuantitative proteomic analysis through LC/MSMS an
OMICSProteomics
STUDY High Throughput
COMMENTSDecreased after glucocorticoid treatment.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21887273
DRUG TARGETBE0000910
MONCLONAL ANTIBODYAnti-alpha 2 Macroglobulin for Human


Record No:54


ACCESS NO100630
GENEAPOA1
DESCRIPTIONApolipoprotein A-I
NCBI ENTREZ ACCESS NO335
UNIPROT ACCESS NOP02647
ORGANISMHuman
DISEASE PHENOTYPESeasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification)
SAMPLENasal fluid
TECHNIQUESQuantitative proteomic analysis through LC/MSMS an
OMICSProteomics
STUDY High Throughput
COMMENTSEnriched in acute phase response pathway.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21887273
DRUG TARGET
MONCLONAL ANTIBODYAnti-Apolipoprotein A I for Human


Record No:55


ACCESS NO100662
GENEA2M
DESCRIPTIONAlpha-2-macroglobulin
NCBI ENTREZ ACCESS NO2
UNIPROT ACCESS NOP01023
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEPlasma proteins
TECHNIQUESMALDI Tof
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSInteracts and captures any proteinases which are encountered as foreign proteins thus providing a humoral defense barrier against pathogens.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21471098
DRUG TARGETBE0000910
MONCLONAL ANTIBODYAnti-alpha 2 Macroglobulin for Human


Record No:56


ACCESS NO100665
GENEAnxa6
DESCRIPTIONAnnexin A 6
NCBI ENTREZ ACCESS NO11749
UNIPROT ACCESS NOP14824
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAsthma induced by Ovalbumin
SAMPLELung tissue
TECHNIQUESMALDI Tof and Western Blotting
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSPlays a role in calcium handling in smooth muscles and may take part in smooth muscle hyperresponsiveness during asthma.Upregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21751807
DRUG TARGET
MONCLONAL ANTIBODYAnti-Annexin VI for Human


Record No:57


ACCESS NO100668
GENEApoa1
DESCRIPTIONApolipoprotein A1
NCBI ENTREZ ACCESS NO11806
UNIPROT ACCESS NOQ00623
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAsthma induced by Ovalbumin
SAMPLELung tissue
TECHNIQUESMALDI Tof and ELISA
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSDownregulated in asthma. May be involved in removing pro-inflammatory lipids which helps to reduce asthma phenotype.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21751807
DRUG TARGET
MONCLONAL ANTIBODYAnti-Apolipoprotein A I for Human


Record No:58


ACCESS NO100680
GENEActb
DESCRIPTIONActin cytoplasmic 1
NCBI ENTREZ ACCESS NO11461
UNIPROT ACCESS NOP60710
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAsthma induced by Ovalbumin
SAMPLELung tissue
TECHNIQUESMALDI Tof
OMICSProteomics
STUDY High Throughput
COMMENTSDownregulated in allergen induced asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21751807
DRUG TARGET
MONCLONAL ANTIBODYAnti-beta Actin for Mouse/Rat/Human


Record No:59


ACCESS NO100682
GENEAcadvl
DESCRIPTIONVery long-chain specific acyl-CoA dehydrogenase
NCBI ENTREZ ACCESS NO11370
UNIPROT ACCESS NOP50544
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAsthma induced by Ovalbumin
SAMPLELung tissue
TECHNIQUESMALDI Tof
OMICSProteomics
STUDY High Throughput
COMMENTSDownregulated in allergen induced asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21751807
DRUG TARGET
MONCLONAL ANTIBODYAnti-ACADVL for Human/Cow/Rat/Mouse


Record No:60


ACCESS NO100718
GENEAPOH
DESCRIPTIONApolipoprotein H
NCBI ENTREZ ACCESS NO350
UNIPROT ACCESS NOP02749
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis treatment with glucocorticoid
SAMPLENasal lavage fluid
TECHNIQUESiTRAQ based proteomics nano LC MS/MS gene expressi
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSAcute phase response signalling protein found in nasal polyps. Downregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20659080
DRUG TARGETBE0002854
MONCLONAL ANTIBODYN/A


Record No:61


ACCESS NO100723
GENEAPOE
DESCRIPTIONapolipoprotein E
NCBI ENTREZ ACCESS NO348
UNIPROT ACCESS NOP02649
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEBlood plasma
TECHNIQUESMALDI TOF MS and LC-MS/MS and Western Blot
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSEssential component of plasma lipoproteins.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19116453
DRUG TARGETBE0001119
MONCLONAL ANTIBODYAnti-Apolipoprotein E for Mouse/Human/Zebrafish


Record No:62


ACCESS NO100736
GENEALB
DESCRIPTIONSerum albumin
NCBI ENTREZ ACCESS NO213
UNIPROT ACCESS NOP02768
ORGANISMHuman
DISEASE PHENOTYPEAsthma challenged with inhaled allergens
SAMPLEBlood plasma
TECHNIQUES2D gel and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTS
GEO_PRIDE_ACCESS_NON/A
REFERENCE19076930
DRUG TARGETBE0000530
MONCLONAL ANTIBODYAnti-Human Serum Albumin for Human


Record No:63


ACCESS NO100737
GENEAPOE
DESCRIPTIONApolipoprotein - E3
NCBI ENTREZ ACCESS NO348
UNIPROT ACCESS NOP02649
ORGANISMHuman
DISEASE PHENOTYPEAsthma challenged with inhaled allergens
SAMPLEBlood plasma
TECHNIQUES2D gel and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSUpregulated in immediate phase reaction of allergic patients.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19076930
DRUG TARGETBE0001119
MONCLONAL ANTIBODYAnti-Apolipoprotein E for Mouse/Human/Zebrafish


Record No:64


ACCESS NO100752
GENEAtf5
DESCRIPTIONActivating transcription factor 5
NCBI ENTREZ ACCESS NO107503
UNIPROT ACCESS NOO70191
ORGANISMbalb C mice
DISEASE PHENOTYPEAllergic asthma after challenge with Aspergillus fumigatus
SAMPLEPeriferal blood monocytes
TECHNIQUESMicroarray (agilent)
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in fungal allergen challenge.Selected based on fold change.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20840155
DRUG TARGET
MONCLONAL ANTIBODYAnti-ATF5 for Human


Record No:65


ACCESS NO100788
GENEAgr2
DESCRIPTIONArginase2
NCBI ENTREZ ACCESS NO23795
UNIPROT ACCESS NOO88312
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAcute and chronic asthma
SAMPLELung Tissue
TECHNIQUESGeneChip Expression 3 (affymetrix) microarray
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSEncodes a protein expressed in mucous secreting cells and is upregulated in mouse model of asthma both during long as well as short term. allergen exposure
GEO_PRIDE_ACCESS_NON/A
REFERENCE19028979
DRUG TARGET
MONCLONAL ANTIBODYAnti-Arg2 for Rat/Dog/Human


Record No:66


ACCESS NO100789
GENEAgr1
DESCRIPTIONArginase1
NCBI ENTREZ ACCESS NO11846
UNIPROT ACCESS NOQ61176
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAcute and chronic asthma
SAMPLELung Tissue
TECHNIQUESGeneChip Expression 3 (affymetrix) microarray
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSUpregulated in asthma. Produced by immune and epithelial cells.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19028979
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:67


ACCESS NO100933
GENEAnkrd10
DESCRIPTIONAnkyrin repeat domain 10
NCBI ENTREZ ACCESS NO102334
UNIPROT ACCESS NOQ99LW0
ORGANISMBALB/C mice
DISEASE PHENOTYPEFood allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin
SAMPLEMesenteric lymph node
TECHNIQUEScDNA microarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after induction with food allergens.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21211037
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:68


ACCESS NO100939
GENEApoa4
DESCRIPTIONApolipoprotein A-IV
NCBI ENTREZ ACCESS NO11808
UNIPROT ACCESS NOP06728
ORGANISMBALB/C mice
DISEASE PHENOTYPEFood allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin
SAMPLEMesenteric lymph node
TECHNIQUEScDNA microarray
OMICSGenomics
STUDY High Throughput
COMMENTSDownregulated after induction with food allergen challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21211037
DRUG TARGET
MONCLONAL ANTIBODYAnti-APOA4 for Human


Record No:69


ACCESS NO100942
GENEAgr2
DESCRIPTIONAnterior gradient 2
NCBI ENTREZ ACCESS NO23795
UNIPROT ACCESS NOO88312
ORGANISMBALB/C mice
DISEASE PHENOTYPEFood allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin
SAMPLEMesenteric lymph node
TECHNIQUEScDNA microarray
OMICSGenomics
STUDY High Throughput
COMMENTSDownregulated after induction with food allergen challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21211037
DRUG TARGET
MONCLONAL ANTIBODYAnti-Anterior Gradient 2 for Rat/Human


Record No:70


ACCESS NO100945
GENEAlox12
DESCRIPTIONArachidonate 12-lipoxygenase
NCBI ENTREZ ACCESS NO11684
UNIPROT ACCESS NOP39655
ORGANISMbalb/c mice
DISEASE PHENOTYPEEpithelial injury in Asthma
SAMPLEBroncho Alveolar Lavage (BALF) fluid
TECHNIQUESWestern blot and ELISA
OMICSOthers
STUDY Low Throughput
COMMENTSCauses epithelial injury in asthma pathogenesis.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23528921
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:71


ACCESS NO100951
GENEAGR2
DESCRIPTIONAnterior gradient 2
NCBI ENTREZ ACCESS NO10551
UNIPROT ACCESS NOO95994
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLETrachea section
TECHNIQUESimmunofloresence immunoblotting RT PCR
OMICSOthers
STUDY Low Throughput
COMMENTSInvolved in Mucin production in asthmatic airways. Upregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22403803
DRUG TARGET
MONCLONAL ANTIBODYAnti-Anterior Gradient 2 for Rat/Human


Record No:72


ACCESS NO100963
GENEADRB2
DESCRIPTION2-adrenergic receptor
NCBI ENTREZ ACCESS NO154
UNIPROT ACCESS NOP07550
ORGANISMHuman
DISEASE PHENOTYPEAsthma and risk of Long Acting Beta Agonist (LABA) treatment
SAMPLEgenomic DNA
TECHNIQUESsequencing and SNP typing
OMICSGenomics
STUDY Low Throughput
COMMENTSA 25 bp promoter polynucleotide insertion at 376 ins and Ile 164 allele are two variants of ADRB2 in asthma patients. These variants account for adverse events during LABA therapy.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24621682
DRUG TARGETBE0000694
MONCLONAL ANTIBODYN/A


Record No:73


ACCESS NO100998
GENEALPL
DESCRIPTIONAlkaline phosphatase (liver/bone/kidney)
NCBI ENTREZ ACCESS NO249
UNIPROT ACCESS NOP05186
ORGANISMHuman
DISEASE PHENOTYPEAsthma with eosinophilic and neutrophilic inflammation
SAMPLESputum
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is a biomarker to discriminate eosinophilic asthma from other asthmatic phenotype. It shows highest expression in neutrophilic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24582314
DRUG TARGETBE0003546
MONCLONAL ANTIBODYAnti-Alkaline Phosphatase for Human


Record No:74


ACCESS NO101026
GENEAdh5 (GSNOR)
DESCRIPTIONS-nitrosoglutathione reductase
NCBI ENTREZ ACCESS NO11532
UNIPROT ACCESS NOP28474
ORGANISMMouse
DISEASE PHENOTYPEAsthma
SAMPLEBroncho Alveolar Lavage (BALF) and plasma
TECHNIQUESBiomarker immunoassay and Tracheal ring bioassay
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSAdministration of GSNOR inhibitor N6022 results in attenuation of both bronchoconstriction and inflammation of asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24405692
DRUG TARGETBE0000009
MONCLONAL ANTIBODYAnti-ADH5 [EPR12886(B)] for Mouse/Rat/Human


Record No:75


ACCESS NO101029
GENEASAH1
DESCRIPTIONAcid ceramidase
NCBI ENTREZ ACCESS NO427
UNIPROT ACCESS NOQ13510
ORGANISMHuman
DISEASE PHENOTYPEAtopic eczema (AE)
SAMPLEVernix
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is strongly upregulated in atopic eczema.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24205894
DRUG TARGET
MONCLONAL ANTIBODYAnti-ASAH1 for Human


Record No:76


ACCESS NO101037
GENEALAD
DESCRIPTIONDelta-aminolevulinic acid dehydratase
NCBI ENTREZ ACCESS NO210
UNIPROT ACCESS NOP13716
ORGANISMHuman
DISEASE PHENOTYPEAtopic eczema (AE)
SAMPLEVernix
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is strongly upregulated in atopic eczema.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24205894
DRUG TARGETBE0000050
MONCLONAL ANTIBODYAnti-ALAD for Human


Record No:77


ACCESS NO101057
GENEAPOH (Apo H)
DESCRIPTIONApolipoprotein H
NCBI ENTREZ ACCESS NO350
UNIPROT ACCESS NOP02749
ORGANISMHuman
DISEASE PHENOTYPEAsthma and aspirin tolerance
SAMPLEPlasma
TECHNIQUES2DE and MALDI-TOF/TOF and ELISA
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSExpression of this protein is decreased in Aspirin-exacerbated respiratory disease (AERD) as compared to aspirin-tolerant asthma (ATA).
GEO_PRIDE_ACCESS_NON/A
REFERENCE24120690
DRUG TARGETBE0002854
MONCLONAL ANTIBODYAnti-Apolipoprotein H for Rat/Human


Record No:78


ACCESS NO101159
GENEANXA1
DESCRIPTIONAnnexin-1
NCBI ENTREZ ACCESS NO301
UNIPROT ACCESS NOP04083
ORGANISMHuman
DISEASE PHENOTYPEAllergy and effect of grass pollen immunothrapy
SAMPLEDendritic cell subtypes (DC1/DC2/DC17/DCreg)
TECHNIQUES2D-DIGE and qPCR
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSThis gene is over expressed after dexamethasone treatment.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22464673
DRUG TARGETBE0000422
MONCLONAL ANTIBODYAnti-Annexin A1 for Human


Record No:79


ACCESS NO101189
GENEALB
DESCRIPTIONHuman serum albumin
NCBI ENTREZ ACCESS NO213
UNIPROT ACCESS NOP02768
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of toluene diisocyanate (TDI)
SAMPLESerum
TECHNIQUESMultiplexed tandem mass spectrometry and western b
OMICSProteomics
STUDY Low Throughput
COMMENTSAlbumin has been identified as a major reaction target for TDI in vivo and TDI–albumin reaction products have been proposed to serve as exposure biomarkers and to act as asthmagens. Vapor phase TDI was found to react with human albumin in a dose-dependent manner with up to 18 potential sites of conjugation of which the most susceptible being Lys351 and the dilysine site Lys413–414.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22206939
DRUG TARGETBE0000530
MONCLONAL ANTIBODYAnti-Human Serum Albumin for Human


Record No:80


ACCESS NO101192
GENEADIPOQ
DESCRIPTIONadiponectin
NCBI ENTREZ ACCESS NO9370
UNIPROT ACCESS NOQ15848
ORGANISMHuman
DISEASE PHENOTYPEAsthma and obesity
SAMPLESerum
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThe adipocytes are the most important source of adiponectin ans its serum levels are markedly decreased in individuals with visceral obesity. Interdisciplinary therapy resulted in increase from 4 to 5.1.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22170805
DRUG TARGET
MONCLONAL ANTIBODYAnti-Adiponectin [19F1] for Mouse/Rat/Human


Record No:81


ACCESS NO101197
GENEAKR1B1
DESCRIPTIONAldose reductase
NCBI ENTREZ ACCESS NO231
UNIPROT ACCESS NOP15121
ORGANISMHuman
DISEASE PHENOTYPEFood allergy
SAMPLEPeripheral blood mononuclear cells
TECHNIQUES2D-DIGE and MALDI-TOF/TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein was found to be down regulated in RAST+ subjects with severe food allergies.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22091390
DRUG TARGETBE0000747
MONCLONAL ANTIBODYN/A


Record No:82


ACCESS NO101258
GENEAkt1 (Akt)
DESCRIPTIONThymoma viral proto-oncogene 1
NCBI ENTREZ ACCESS NO11651
UNIPROT ACCESS NOP31750
ORGANISMMouse
DISEASE PHENOTYPEAsthma and effct of the drug 'Artesunate'
SAMPLELung tissue
TECHNIQUESImmunoblot
OMICSOthers
STUDY Low Throughput
COMMENTSArtesunate markedly inhibited the EGF-induced phosphorylation of Akt. Thus EGF induced activation of inflammatory PI3K/Akt signaling pathway is suppressed.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21695271
DRUG TARGET
MONCLONAL ANTIBODYAnti-AKT1 for Mouse/Human


Record No:83


ACCESS NO101267
GENEADIPOQ
DESCRIPTIONadiponectin
NCBI ENTREZ ACCESS NO9370
UNIPROT ACCESS NOQ15848
ORGANISMHuman
DISEASE PHENOTYPEAsthma and obesity
SAMPLEBroncho Alveolar Lavage (BAL) and plasma
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSIncreasing BMI was marginally and inversely associated with BAL adiponectin.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21332421
DRUG TARGET
MONCLONAL ANTIBODYAnti-Adiponectin [19F1] for Mouse/Rat/Human


Record No:84


ACCESS NO101276
GENEALB
DESCRIPTIONSerum Albumin
NCBI ENTREZ ACCESS NO213
UNIPROT ACCESS NOP02768
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEBlood
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSIncreased expression in rapid onset asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20832159
DRUG TARGETBE0000530
MONCLONAL ANTIBODYAnti-Human Serum Albumin for Human


Record No:85


ACCESS NO101314
GENEARHGDIB
DESCRIPTIONRho GDP dissociation inhibitor (GDI) beta
NCBI ENTREZ ACCESS NO397
UNIPROT ACCESS NOP52566
ORGANISMHuman
DISEASE PHENOTYPEAllergy(Comparison of Dendritic cell proteome in atopic and non atopic patients)
SAMPLEDendritic cell
TECHNIQUESMALDI Tof/Tof
OMICSProteomics
STUDY High Throughput
COMMENTSInvolved in cellular motility/ negative regulation of cellular adhesion and signal transduction.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19494521
DRUG TARGET
MONCLONAL ANTIBODYAnti-D4 GDI for Mouse/Rat/Human


Record No:86


ACCESS NO101333
GENEA2M
DESCRIPTIONAlpha2-macroglobulin
NCBI ENTREZ ACCESS NO2
UNIPROT ACCESS NOP01023
ORGANISMHuman
DISEASE PHENOTYPEAllergic airway disease
SAMPLENasal Lavage
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSIncreased after nasal allergen challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19400896
DRUG TARGETBE0000910
MONCLONAL ANTIBODYAnti-alpha 2 Macroglobulin for Human


Record No:87


ACCESS NO101334
GENEAMCase
DESCRIPTIONChitinase acidic 1
NCBI ENTREZ ACCESS NO81600
UNIPROT ACCESS NOQ91XA9
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAsthma (Effect of andrographolide on NF kappa beta pathway in asthma)
SAMPLEBronchial Epithelial cells
TECHNIQUESRT-PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSSuppressed after andrographolide treatment.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19201922
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:88


ACCESS NO101349
GENEABCA-1
DESCRIPTIONATP-binding cassette A1
NCBI ENTREZ ACCESS NO313210
UNIPROT ACCESS NOQ80ZB2
ORGANISMMale Brown Norway rats
DISEASE PHENOTYPEAsthma (LXR agonist treated rat)
SAMPLETracheal tissue
TECHNIQUESRT-PCR/ELISA
OMICSGenomics
STUDY Low Throughput
COMMENTSmRNA increasedafter LXR agonist treatment.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18768884
DRUG TARGETBE0000119
MONCLONAL ANTIBODYAnti-ABCA1 for Mouse


Record No:89


ACCESS NO101351
GENEALB
DESCRIPTIONAlbumin
NCBI ENTREZ ACCESS NO213
UNIPROT ACCESS NOP02768
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEExhaled Breath condensate
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSHigher in smoking people compared to asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18513240
DRUG TARGETBE0000530
MONCLONAL ANTIBODYAnti-Human Serum Albumin for Human


Record No:90


ACCESS NO101353
GENEArpc4
DESCRIPTIONARP 2/3 complex subunit 5
NCBI ENTREZ ACCESS NO68089
UNIPROT ACCESS NOP59999
ORGANISMMouse
DISEASE PHENOTYPEChronic Asthma
SAMPLELung Tissue and Broncho Alveolar Lavage (BAL) flui
TECHNIQUESMALDI Tof/Tof
OMICSProteomics
STUDY High Throughput
COMMENTSInvolved in cell migration and adhesion. Significantly upregulated by 2 fold.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18594147
DRUG TARGETBE0004254
MONCLONAL ANTIBODYN/A


Record No:91


ACCESS NO101368
GENEAk1
DESCRIPTIONAdenylate kinase 1
NCBI ENTREZ ACCESS NO11636
UNIPROT ACCESS NOQ9R0Y5
ORGANISMMouse
DISEASE PHENOTYPEChronic Asthma
SAMPLELung Tissue and Broncho Alveolar Lavage (BAL) flui
TECHNIQUESMALDI Tof/Tof
OMICSProteomics
STUDY High Throughput
COMMENTSInvolved in cellular metabolism and expressed in chronic asthma mouse model.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18594147
DRUG TARGETBE0001262
MONCLONAL ANTIBODYAnti-Adenylate Kinase 1 for Mouse/Rat/Human


Record No:92


ACCESS NO101376
GENEApoa1
DESCRIPTIONApolipoprotein A-I
NCBI ENTREZ ACCESS NO11806
UNIPROT ACCESS NOQ00623
ORGANISMMouse
DISEASE PHENOTYPEChronic Asthma
SAMPLELung Tissue and Broncho Alveolar Lavage (BAL) flui
TECHNIQUESMALDI Tof/Tof
OMICSProteomics
STUDY High Throughput
COMMENTSUpregulated in chronic asthma model.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18594147
DRUG TARGETBE0000936
MONCLONAL ANTIBODYAnti-Apolipoprotein A I for Human


Record No:93


ACCESS NO101384
GENEApcs
DESCRIPTIONSerum amyloid P component
NCBI ENTREZ ACCESS NO20219
UNIPROT ACCESS NOP12246
ORGANISMMouse
DISEASE PHENOTYPEChronic Asthma
SAMPLELung Tissue and Broncho Alveolar Lavage (BAL) flui
TECHNIQUESMALDI Tof/Tof
OMICSProteomics
STUDY High Throughput
COMMENTSReduced expression in chronically asthmatic mouse.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18594147
DRUG TARGETBE0001213
MONCLONAL ANTIBODYAnti-Serum Amyloid P for Human


Record No:94


ACCESS NO101394
GENEAnxa3
DESCRIPTIONAnnexin A3
NCBI ENTREZ ACCESS NO11745
UNIPROT ACCESS NOO35639
ORGANISMMouse
DISEASE PHENOTYPEChronic Asthma
SAMPLELung Tissue and Broncho Alveolar Lavage (BAL) flui
TECHNIQUESMALDI Tof/Tof
OMICSProteomics
STUDY High Throughput
COMMENTSElevated in chronically inflammed lungs. Controls Chloride channel activity for mucus production.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18594147
DRUG TARGETBE0003201
MONCLONAL ANTIBODYAnti-Annexin A3 for Human(predicted).


Record No:95


ACCESS NO101395
GENEAnxa5
DESCRIPTIONAnnexin A5
NCBI ENTREZ ACCESS NO11747
UNIPROT ACCESS NOP48036
ORGANISMMouse
DISEASE PHENOTYPEChronic Asthma
SAMPLELung Tissue and Broncho Alveolar Lavage (BAL) flui
TECHNIQUESMALDI Tof/Tof
OMICSProteomics
STUDY High Throughput
COMMENTSElevated in chronically inflammed lungs. Controls Chloride channel activity for mucus production.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18594147
DRUG TARGETBE0004149
MONCLONAL ANTIBODYAnti-Annexin V for Mouse/Rat/Human


Record No:96


ACCESS NO101442
GENEAsprv1
DESCRIPTIONAspartic peptidase retroviral-like 1
NCBI ENTREZ ACCESS NO67855
UNIPROT ACCESS NOQ09PK2
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3hours and 12 hours of fungal allergen induction in asthmatic mice.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:97


ACCESS NO101474
GENEArid5a
DESCRIPTIONAT rich interactive domain 5A (MRF1-like)
NCBI ENTREZ ACCESS NO214855
UNIPROT ACCESS NOQ3U108
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3 and 12 hours of fungal allergen challenge in asthmatic mice.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:98


ACCESS NO101484
GENEArg2
DESCRIPTIONArginase 2
NCBI ENTREZ ACCESS NO11847
UNIPROT ACCESS NOO08691
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray and RT PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSSignificantly increased after 1 and 18 hour timepoints.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGETBE0000758
MONCLONAL ANTIBODYAnti-Arg2 for Human/Rat/Dog


Record No:99


ACCESS NO101519
GENEAdam8
DESCRIPTIONA disintegrin and metallopeptidase domain 8
NCBI ENTREZ ACCESS NO11501
UNIPROT ACCESS NOQ05910
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3 and 12 hours of allergen induction in asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-ADAM8 for Human/Mouse/Rat


Record No:100


ACCESS NO101528
GENEADIPOQ
DESCRIPTIONAdiponectin
NCBI ENTREZ ACCESS NO9370
UNIPROT ACCESS NOQ15848
ORGANISMHuman
DISEASE PHENOTYPEAsthma rhinoconjunctivitis and eczema
SAMPLEEDTA added blood plasma
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSLow adiponectin is associated with rhinoconjunctivitis and hay fever in girls and higher prevalence of asthma in general.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18331416
DRUG TARGET
MONCLONAL ANTIBODYAnti-Adiponectin for Mouse/Rat/Human


Record No:101


ACCESS NO101530
GENEALB
DESCRIPTIONAlbumin
NCBI ENTREZ ACCESS NO213
UNIPROT ACCESS NOP02768
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEExhaled breath condensate
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSHigher in smoking group.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18513240
DRUG TARGETBE0000530
MONCLONAL ANTIBODYAnti-Human Serum Albumin for Human


Record No:102


ACCESS NO101532
GENEALB
DESCRIPTIONAlbumin
NCBI ENTREZ ACCESS NO213
UNIPROT ACCESS NOP02768
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEVenous blood
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSDecreased in asthmatics after etanercept administration.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18245148
DRUG TARGETBE0000530
MONCLONAL ANTIBODYAnti-Human Serum Albumin for Human


Record No:103


ACCESS NO101545
GENEAMcase
DESCRIPTIONChitinase acidic 1
NCBI ENTREZ ACCESS NO81600
UNIPROT ACCESS NOQ91XA9
ORGANISMFemale Balb/c Mice
DISEASE PHENOTYPEAsthma(Effect of Glycogen synthase kinase-3 beta inhibition on asthma)
SAMPLELung tissue
TECHNIQUESRT-PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSIt is involved in airway remodelling and inflammation.Upregulated after OVA challenge but downregulated after GSK-3b inhibitor induction.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17556716
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:104


ACCESS NO101562
GENEAGR2
DESCRIPTIONAnterior gradient 2
NCBI ENTREZ ACCESS NO23795
UNIPROT ACCESS NOO88312
ORGANISMBalb/C wild-type mice
DISEASE PHENOTYPEAllergic asthma induced by both Ovalbumin and mIL-13
SAMPLELung tissue
TECHNIQUESGene Chip microarray
OMICSGenomics
STUDY High Throughput
COMMENTSInterleukin 13 induced gene. Involved in secreted signal transduction.
GEO_PRIDE_ACCESS_NON/A
REFERENCE16402082
DRUG TARGET
MONCLONAL ANTIBODYAnti-Anterior Gradient 2 for Rat/Human


Record No:105


ACCESS NO101574
GENEARG1
DESCRIPTIONArginase liver
NCBI ENTREZ ACCESS NO11846
UNIPROT ACCESS NOQ61176
ORGANISMBalb/C wild-type mice
DISEASE PHENOTYPEAllergic asthma induced by both Ovalbumin and mIL-13
SAMPLELung tissue
TECHNIQUESGene Chip microarray
OMICSGenomics
STUDY High Throughput
COMMENTSInvolved in metabolism and induced by both OVA challenge and IL 13 induction.
GEO_PRIDE_ACCESS_NON/A
REFERENCE16402082
DRUG TARGETBE0000286
MONCLONAL ANTIBODYAnti-liver Arginase for Human


Record No:106


ACCESS NO101600
GENEActg2
DESCRIPTIONActin gamma 2 smooth muscle enteric
NCBI ENTREZ ACCESS NO11468
UNIPROT ACCESS NOP63268
ORGANISMBalb/C wild-type mice
DISEASE PHENOTYPEAllergic asthma induced by both Ovalbumin and mIL-13
SAMPLELung tissue
TECHNIQUESGene Chip microarray
OMICSGenomics
STUDY High Throughput
COMMENTSCytoskeletal protein expressed after IL 13 induction.
GEO_PRIDE_ACCESS_NON/A
REFERENCE16402082
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:107


ACCESS NO101612
GENEAcp5
DESCRIPTIONAcid phosphatase 5 tartrate resistant
NCBI ENTREZ ACCESS NO11433
UNIPROT ACCESS NOQ05117
ORGANISMBalb/C wild-type mice
DISEASE PHENOTYPEAllergic asthma induced by both Ovalbumin and mIL-13
SAMPLELung tissue
TECHNIQUESGene Chip microarray
OMICSGenomics
STUDY High Throughput
COMMENTSInvolved in metabolism and expressed after IL 13 induction.
GEO_PRIDE_ACCESS_NON/A
REFERENCE16402082
DRUG TARGET
MONCLONAL ANTIBODYAnti-Tartrate Resistant Acid Phosphatase for Human


Record No:108


ACCESS NO101613
GENEAk2
DESCRIPTIONAdenylate kinase 2
NCBI ENTREZ ACCESS NO11637
UNIPROT ACCESS NOQ9WTP6
ORGANISMBalb/C wild-type mice
DISEASE PHENOTYPEAllergic asthma induced by both Ovalbumin and mIL-13
SAMPLELung tissue
TECHNIQUESGene Chip microarray
OMICSGenomics
STUDY High Throughput
COMMENTSInvolved in metabolism and expressed after IL 13 induction.
GEO_PRIDE_ACCESS_NON/A
REFERENCE16402082
DRUG TARGETBE0004477
MONCLONAL ANTIBODYAnti-AK2 for Mouse/Rat/Human


Record No:109


ACCESS NO101620
GENEArmet
DESCRIPTIONMesencephalic astrocyte-derived neurotrophic factor
NCBI ENTREZ ACCESS NO74840
UNIPROT ACCESS NOQ3TMX5
ORGANISMBalb/C wild-type mice
DISEASE PHENOTYPEAllergic asthma induced by both Ovalbumin and mIL-13
SAMPLELung tissue
TECHNIQUESGene Chip microarray
OMICSGenomics
STUDY High Throughput
COMMENTSExpressed after IL 13 induction.
GEO_PRIDE_ACCESS_NON/A
REFERENCE16402082
DRUG TARGET
MONCLONAL ANTIBODYAnti-ARMET for Human


Record No:110


ACCESS NO101642
GENEa-SMA(ACTA2)
DESCRIPTIONAlpha smooth muscle actin
NCBI ENTREZ ACCESS NO59
UNIPROT ACCESS NOP62736
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEFibroblasts from Broncho Alveolar Lavage (BAL) Flu
TECHNIQUESMALDI Tof Tof
OMICSProteomics
STUDY High Throughput
COMMENTSOverexpressed in mild asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE16430780
DRUG TARGET
MONCLONAL ANTIBODYAnti-alpha smooth muscle Actin for Mouse/Rat/Rabbit/Human


Record No:111


ACCESS NO101653
GENEArhgdib
DESCRIPTIONRho GDP dissociation inhibitor beta
NCBI ENTREZ ACCESS NO11857
UNIPROT ACCESS NOQ61599
ORGANISMMale BALB/c mice
DISEASE PHENOTYPEAllergic asthma
SAMPLELung tissue
TECHNIQUES2D electrophoresis and MALDI Tof Tof
OMICSProteomics
STUDY High Throughput
COMMENTSUpregulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE16100447
DRUG TARGET
MONCLONAL ANTIBODYAnti-D4 GDI for Mouse/Rat/Human


Record No:112


ACCESS NO101693
GENEATP2A2 (SARCA2)
DESCRIPTIONSarco/endoplasmic reticulum Calcium pump
NCBI ENTREZ ACCESS NO488
UNIPROT ACCESS NOP16615
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEAirway smooth muscle cells (ASM)
TECHNIQUESImmunochemistry and rela time PCR and cell biology
OMICSOthers
STUDY Low Throughput
COMMENTSSERCA2 mRNA and protein expression is reduced in ASM cells from subjects with moderately severe asthma. Rises in intracellular calcium following cell surface receptor-induced SR activation or inhibition of SERCA-mediated Calcium re-uptake were attenuated in ASM cells from asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19541629
DRUG TARGET
MONCLONAL ANTIBODYAnti-SERCA2 ATPase [2A7-A1] for Mouse/Rat/Human


Record No:113


ACCESS NO101702
GENEADIPOQ
DESCRIPTIONAdiponectin
NCBI ENTREZ ACCESS NO9370
UNIPROT ACCESS NOQ15848
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis growth factor is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-Adiponectin [19F1] for Mouse/Rat/Human


Record No:114


ACCESS NO101738
GENEASAH1
DESCRIPTIONN-Acylsphingosine amidohydrolase
NCBI ENTREZ ACCESS NO427
UNIPROT ACCESS NOB1B5P6
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-ASAH1 [1A7] for Human


Record No:115


ACCESS NO101742
GENEADH5
DESCRIPTIONAlcohol dehydrogenase class III x chain
NCBI ENTREZ ACCESS NO128
UNIPROT ACCESS NOD6RFE4
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-ADH5 [EPR12885(B)] for Mouse/Rat/Human


Record No:116


ACCESS NO101743
GENEADH1B
DESCRIPTIONAlcohol dehydrogenase
NCBI ENTREZ ACCESS NO125
UNIPROT ACCESS NOB7ZB36
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0000400
MONCLONAL ANTIBODYAnti-ADH1B [4F12] for rat/Human


Record No:117


ACCESS NO101754
GENEANG
DESCRIPTIONAngiogenin (ribonuclease 5)
NCBI ENTREZ ACCESS NO283
UNIPROT ACCESS NOANG
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0001181
MONCLONAL ANTIBODYAnti-Angiotensin II Type 1 Receptor [1E10-1A9] for Rat/Rabbit/Human


Record No:118


ACCESS NO101758
GENEAZGP1
DESCRIPTIONZinc-alpha-2-glycoprotein
NCBI ENTREZ ACCESS NO563
UNIPROT ACCESS NOP25311
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis local matrix protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0002857
MONCLONAL ANTIBODYN/A


Record No:119


ACCESS NO101772
GENEAPCS
DESCRIPTIONSerum amyloid P-component (SAP)
NCBI ENTREZ ACCESS NO325
UNIPROT ACCESS NOP02743
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis acute phase protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0001213
MONCLONAL ANTIBODYAnti-Serum Amyloid P [EP1018Y] for Human


Record No:120


ACCESS NO101775
GENEAPOB
DESCRIPTIONApolipoprotein B
NCBI ENTREZ ACCESS NO338
UNIPROT ACCESS NOP04114
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis apolipoprotein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0004845
MONCLONAL ANTIBODYAnti-APOBEC2 [EPR11285(B)] for Human


Record No:121


ACCESS NO101776
GENEAPOA4
DESCRIPTIONApolipoprotein A-IV
NCBI ENTREZ ACCESS NO337
UNIPROT ACCESS NOP06727
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis apolipoprotein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-APOA4 [1D4C11] for Human


Record No:122


ACCESS NO101777
GENEAPOE
DESCRIPTIONApolipoprotein E (apoE)
NCBI ENTREZ ACCESS NO348
UNIPROT ACCESS NOP02649
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis apolipoprotein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0001119
MONCLONAL ANTIBODYAnti-ApoER2 [EPR3326] for Rat/Mouse/Human


Record No:123


ACCESS NO101779
GENEAPOH
DESCRIPTIONApolipoprotein H (apo-H)
NCBI ENTREZ ACCESS NO350
UNIPROT ACCESS NOJ3QRN2
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis apolipoprotein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0002854
MONCLONAL ANTIBODYAnti-Apolipoprotein H [EPR2898(2)] for Rat/Human


Record No:124


ACCESS NO101780
GENEAPOL1
DESCRIPTIONApolipoprotein L1
NCBI ENTREZ ACCESS NO8542
UNIPROT ACCESS NOB1AH96
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis apolipoprotein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-Apolipoprotein L 1 [EPR2907(2)] for Human


Record No:125


ACCESS NO101781
GENEAPOD
DESCRIPTIONApolipoprotein D (apoD)
NCBI ENTREZ ACCESS NO347
UNIPROT ACCESS NOC9JX71
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis apolipoprotein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-Apolipoprotein D [EPR2916] for Human


Record No:126


ACCESS NO101782
GENEAPOA2
DESCRIPTIONApolipoprotein A-II (apoA-II)
NCBI ENTREZ ACCESS NO336
UNIPROT ACCESS NOQ76EI7
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis apolipoprotein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-Apolipoprotein A II [4F3] for Human


Record No:127


ACCESS NO101783
GENEAPOM
DESCRIPTIONApolipoprotein M (apoM)
NCBI ENTREZ ACCESS NO55937
UNIPROT ACCESS NOQ5SRP5
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis apolipoprotein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0004245
MONCLONAL ANTIBODYAnti-Apolipoprotein M [8F12C6B8] for Human


Record No:128


ACCESS NO101784
GENEAPOC1
DESCRIPTIONApolipoprotein C-I (apoC-I)
NCBI ENTREZ ACCESS NO341
UNIPROT ACCESS NOK7EKP1
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis apolipoprotein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-Apolipoprotein CI for Human


Record No:129


ACCESS NO101785
GENEAPOC2
DESCRIPTIONApolipoprotein C-II (apoC-II)
NCBI ENTREZ ACCESS NO344
UNIPROT ACCESS NOQ6P163
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis apolipoprotein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:130


ACCESS NO101786
GENEAPOC3
DESCRIPTIONApolipoprotein C-III (apoC-III)
NCBI ENTREZ ACCESS NO345
UNIPROT ACCESS NOB0YIW2
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis apolipoprotein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-Apolipoprotein CIII [EP1372Y] for Human


Record No:131


ACCESS NO101787
GENEAPOC4
DESCRIPTIONApolipoprotein C-IV (apoC-IV)
NCBI ENTREZ ACCESS NO346
UNIPROT ACCESS NOK7EMC3
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis apolipoprotein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-Apolipoprotein CIV for Human


Record No:132


ACCESS NO101793
GENEAMBP
DESCRIPTIONAMBP protein (#-1 microglycoprotein)
NCBI ENTREZ ACCESS NO259
UNIPROT ACCESS NOP78492
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis serum protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-Alpha 1 microglobulin [BN11.10] for Rat/Human


Record No:133


ACCESS NO101796
GENEAHSG
DESCRIPTIONalpha-2-HS-glycoprotein (Ba-alpha-2-glycoprotein)
NCBI ENTREZ ACCESS NO197
UNIPROT ACCESS NOC9JV77
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis serum protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-AHSG [2H2] for Human


Record No:134


ACCESS NO101806
GENEARPC4
DESCRIPTIONActin-related protein 2/3 complex subunit 4
NCBI ENTREZ ACCESS NO10093
UNIPROT ACCESS NOP59998
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis cytoskeletal protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0004254
MONCLONAL ANTIBODYN/A


Record No:135


ACCESS NO101807
GENEARPC1B
DESCRIPTIONActin-related protein 2/3 complex subunit 1B
NCBI ENTREZ ACCESS NO10095
UNIPROT ACCESS NOO15143
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis cytoskeletal protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0004249
MONCLONAL ANTIBODYN/A


Record No:136


ACCESS NO101809
GENEACTR3
DESCRIPTIONActin-related protein 3 (actin-2)
NCBI ENTREZ ACCESS NO10096
UNIPROT ACCESS NOP61158
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis cytoskeletal protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0004251
MONCLONAL ANTIBODYN/A


Record No:137


ACCESS NO101810
GENEANXA3
DESCRIPTIONAnnexin A3 (annexin III) (lipocortin III)
NCBI ENTREZ ACCESS NO306
UNIPROT ACCESS NOP12429
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0003201
MONCLONAL ANTIBODYN/A


Record No:138


ACCESS NO101811
GENEARF3
DESCRIPTIONADP-ribosylation factor 3
NCBI ENTREZ ACCESS NO377
UNIPROT ACCESS NOP61204
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:139


ACCESS NO101817
GENEANXA11
DESCRIPTIONAnnexin A11 (annexin XI)
NCBI ENTREZ ACCESS NO311
UNIPROT ACCESS NOP50995
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:140


ACCESS NO101834
GENEACE
DESCRIPTIONAngiotensin-converting enzyme (ACE)
NCBI ENTREZ ACCESS NO1636
UNIPROT ACCESS NOP12821
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is down regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0000221
MONCLONAL ANTIBODYN/A


Record No:141


ACCESS NO101840
GENEAPOA2
DESCRIPTIONApolipoprotein A-II
NCBI ENTREZ ACCESS NO336
UNIPROT ACCESS NOP02652
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis
SAMPLENasal mucus
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSIt showed 9.7 fold upregulation in rhinitis patients. It is involved in lipid metabolism and signaling and are present in high-density lipoproteins and chylomicrons.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24290289
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:142


ACCESS NO101841
GENEA2M
DESCRIPTIONalpha 2-Macroglobulin
NCBI ENTREZ ACCESS NO2
UNIPROT ACCESS NOP01023
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis
SAMPLENasal mucus
TECHNIQUESLC-MS/MS and western blot
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSIt showed 4.5 fold upregulation in rhinitis patients. It is the only significantly increased antiproteinase in mucus from patients with allergic rhinitis with potential for inhibition of all 4 classes of proteinases. It traps the enzyme and decreases its proteolytic activity for high-weight substrates by hydrolyzing a thioester bond and covalent binding to the protease.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24290289
DRUG TARGETBE0000910
MONCLONAL ANTIBODYN/A


Record No:143


ACCESS NO101842
GENEAPOA1
DESCRIPTIONApolipoprotein A-I
NCBI ENTREZ ACCESS NO335
UNIPROT ACCESS NOP02647
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis
SAMPLENasal mucus
TECHNIQUESLC-MS/MS and western blot
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSIt showed 3.2 fold upregulation in rhinitis patients. It is involved in lipid metabolism and signaling and are present in high-density lipoproteins and chylomicrons. It supresses bacterial growth and acts as an anti-inflammatory agent. Its upregulation in patients with allergic rhinitis could reflect the recurring inflammation of the nasal mucosa in patients with allergic rhinitis.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24290289
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:144


ACCESS NO101856
GENEACVR2A
DESCRIPTIONActivin A receptor type II
NCBI ENTREZ ACCESS NO92
UNIPROT ACCESS NOP27037
ORGANISMHuman
DISEASE PHENOTYPEAllergic Rhinitis induced by pollen allergen
SAMPLENasal lavage fluids
TECHNIQUESAffymetrix microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis anti inflammatory gene showed lower expression levels in patients than in controls.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15836756
DRUG TARGET
MONCLONAL ANTIBODYAnti-Activin Receptor Type IIA for Mouse/Rat/Human


Record No:145


ACCESS NO101870
GENEAPOE
DESCRIPTIONApolipoprotein E
NCBI ENTREZ ACCESS NO348
UNIPROT ACCESS NOP02649
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPlasma
TECHNIQUES2D-PAGE and MALDI-TOF/TOF and Immunoblot
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSThis protein is down regulated in atopic dermatitis patient. It is suggested that inflammation could impair lipoprotein metabolism and produce a wide variety of changes in the plasma concentrations of lipids and lipoproteins.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19116453
DRUG TARGETBE0001119
MONCLONAL ANTIBODYAnti-ApoER2 for Rat/Human


Record No:146


ACCESS NO101871
GENEAPOA1
DESCRIPTIONProapolipoprotein
NCBI ENTREZ ACCESS NO335
UNIPROT ACCESS NOP02647
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPlasma
TECHNIQUES2D-PAGE and MALDI-TOF/TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is up regulated in atopic dermatitis patient.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19116453
DRUG TARGET
MONCLONAL ANTIBODYAnti-Apolipoprotein A I for Human


Record No:147


ACCESS NO101876
GENEAHCY
DESCRIPTIONAdenosylhomocysteinase
NCBI ENTREZ ACCESS NO191
UNIPROT ACCESS NOP23526
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEFibroblast
TECHNIQUES2D-PAGE and MALDI-TOF/TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic fibroblasts comparative to normal fibroblasts.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15468290
DRUG TARGETBE0001684
MONCLONAL ANTIBODYN/A


Record No:148


ACCESS NO101880
GENEANXA5
DESCRIPTIONAnnexin A5
NCBI ENTREZ ACCESS NO308
UNIPROT ACCESS NOP08758
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEFibroblast
TECHNIQUES2D-PAGE and MALDI-TOF/TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic fibroblasts comparative to normal fibroblasts.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15468290
DRUG TARGETBE0004149
MONCLONAL ANTIBODYAnti-Annexin V for Human


Record No:149


ACCESS NO101898
GENEAKT1
DESCRIPTIONRAC-a-serine/threonine kinase
NCBI ENTREZ ACCESS NO207
UNIPROT ACCESS NOP31749
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPeripheral blood eosinophils
TECHNIQUES2DE-PAGE and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic dermatitis patients eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15832365
DRUG TARGETBE0000428
MONCLONAL ANTIBODYAnti-AKT1 (phospho S473) for Mouse/Rat/Human


Record No:150


ACCESS NO101899
GENEARIH1
DESCRIPTIONAriadne-1 protein homologue (ARI-1)
NCBI ENTREZ ACCESS NO25820
UNIPROT ACCESS NOQ9Y4X5
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPeripheral blood eosinophils
TECHNIQUES2DE-PAGE and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic dermatitis patients eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15832365
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:151


ACCESS NO101912
GENEACADVL
DESCRIPTIONAcyl-CoA dehydrogenase
NCBI ENTREZ ACCESS NO37
UNIPROT ACCESS NOP49748
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPeripheral blood eosinophils
TECHNIQUES2DE-PAGE and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic dermatitis patients eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15832365
DRUG TARGET
MONCLONAL ANTIBODYAnti-ACADVL for Mouse/Rat/Human


Record No:152


ACCESS NO101916
GENEARFGAP3
DESCRIPTIONADP-ribosylation factor GTPase-activating protein 3
NCBI ENTREZ ACCESS NO26286
UNIPROT ACCESS NOQ9NP61
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPeripheral blood eosinophils
TECHNIQUES2DE-PAGE and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic dermatitis patients eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15832365
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:153


ACCESS NO101917
GENEACTB
DESCRIPTIONActin
NCBI ENTREZ ACCESS NO396526
UNIPROT ACCESS NOP60706
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPeripheral blood eosinophils
TECHNIQUES2DE-PAGE and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic dermatitis patients eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15832365
DRUG TARGET
MONCLONAL ANTIBODYAnti-beta Actin for Mouse/Rat/Human


Record No:154


ACCESS NO101922
GENEAP2M1
DESCRIPTIONPlasma membrane adaptor AP-2 protein
NCBI ENTREZ ACCESS NO1173
UNIPROT ACCESS NOQ96CW1
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPeripheral blood eosinophils
TECHNIQUES2DE-PAGE and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic dermatitis patients eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15832365
DRUG TARGET
MONCLONAL ANTIBODYAnti-AP2M1 for Mouse/Rat/Human


Record No:155


ACCESS NO101934
GENEATM
DESCRIPTIONSerine-protein kinase ATM (Ataxia telangiectasia mutated)
NCBI ENTREZ ACCESS NO472
UNIPROT ACCESS NOQ13315
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPeripheral blood eosinophils
TECHNIQUES2DE-PAGE and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic dermatitis patients eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15832365
DRUG TARGETBE0004874
MONCLONAL ANTIBODYAnti-ATM for Mouse/Rat/Human


Record No:156


ACCESS NO101950
GENEALDH3B1
DESCRIPTIONB1 transcript variant 2
NCBI ENTREZ ACCESS NO221
UNIPROT ACCESS NOP43353
ORGANISMHuman(Asthmatic children)
DISEASE PHENOTYPEAsthma( Mite sensitized asthma)
SAMPLEPeripheral Blood Mononuclear Cells
TECHNIQUESMicroarray and RT-PCR
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in asthmatic children.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19187333
DRUG TARGETBE0000446
MONCLONAL ANTIBODYN/A


Record No:157


ACCESS NO101981
GENEARHGAP5
DESCRIPTIONRho GTPase activating protein 5
NCBI ENTREZ ACCESS NO394
UNIPROT ACCESS NOQ13017
ORGANISMHuman
DISEASE PHENOTYPEAsthma and allergic rhinitis
SAMPLEEpithelial cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDownregulated in patients with allergic rhinitis with or without asthma in the upper airways.
GEO_PRIDE_ACCESS_NOGSE51392
REFERENCE24475887
DRUG TARGET
MONCLONAL ANTIBODYAnti-RhoGAP for Mouse/Rat/Human


Record No:158


ACCESS NO101982
GENEANKH
DESCRIPTIONANKH inorganic pyrophosphate transport regulator
NCBI ENTREZ ACCESS NO56172
UNIPROT ACCESS NOQ9HCJ1
ORGANISMHuman
DISEASE PHENOTYPEAsthma and allergic rhinitis
SAMPLEEpithelial cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDownregulated in patients with allergic rhinitis with or without asthma in the upper airways.
GEO_PRIDE_ACCESS_NOGSE51392
REFERENCE24475887
DRUG TARGET
MONCLONAL ANTIBODYAnti-ANKH for Mouse/Rat/Human


Record No:159


ACCESS NO101987
GENEAHNAK
DESCRIPTIONAHNAK nucleoprotein
NCBI ENTREZ ACCESS NO79026
UNIPROT ACCESS NOQ09666
ORGANISMHuman
DISEASE PHENOTYPEAsthma and allergic rhinitis
SAMPLEEpithelial cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDownregulated in patients with allergic rhinitis with or without asthma in the upper airways.
GEO_PRIDE_ACCESS_NOGSE51392
REFERENCE24475887
DRUG TARGET
MONCLONAL ANTIBODYAnti-AHNAK for Mouse/Human


Record No:160


ACCESS NO102023
GENEAKAP12
DESCRIPTIONA kinase (PRKA) anchor protein 12
NCBI ENTREZ ACCESS NO9590
UNIPROT ACCESS NOQ02952
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis and asthma
SAMPLEBronchial epithelial cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput
COMMENTSHighly expressed in patients with allergic rhinitis and asthma.(Data in supplimentary table).
GEO_PRIDE_ACCESS_NOGSE44037
REFERENCE24282527
DRUG TARGET
MONCLONAL ANTIBODYAnti-AKAP12 for Human


Record No:161


ACCESS NO102048
GENEAHI1
DESCRIPTIONAbelson helper integration site 1
NCBI ENTREZ ACCESS NO54806
UNIPROT ACCESS NOQ8N157
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis and asthma
SAMPLENasal epithelial cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput
COMMENTSHighly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table).
GEO_PRIDE_ACCESS_NOGSE44037
REFERENCE24282527
DRUG TARGET
MONCLONAL ANTIBODYAnti-AHI1 for Mouse


Record No:162


ACCESS NO102049
GENEARMCX1
DESCRIPTIONArmadillo repeat containing X-linked 1
NCBI ENTREZ ACCESS NO51309
UNIPROT ACCESS NOQ9P291
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis and asthma
SAMPLENasal epithelial cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput
COMMENTSHighly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table).
GEO_PRIDE_ACCESS_NOGSE44037
REFERENCE24282527
DRUG TARGET
MONCLONAL ANTIBODYAnti-ARMCX1 for Mouse/Rat/Human


Record No:163


ACCESS NO102079
GENEALOX5
DESCRIPTIONArachidonate 5-lipoxygenase
NCBI ENTREZ ACCESS NO240
UNIPROT ACCESS NOP09917
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDifferentially expressed in asthma. Involved in leukotriene and prostaglandin signalling.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGETBE0000248
MONCLONAL ANTIBODYAnti-5 Lipoxygenase for Mouse/Rat/Human


Record No:164


ACCESS NO102088
GENEARRDC2
DESCRIPTIONArrestin domain containing 2
NCBI ENTREZ ACCESS NO27106
UNIPROT ACCESS NOQ8TBH0
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDifferentially expressed in asthma. Involved in signal transduction.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:165


ACCESS NO102101
GENEAPBB1IP
DESCRIPTIONRap1-interacting adaptor molecule
NCBI ENTREZ ACCESS NO54518
UNIPROT ACCESS NOQ7Z5R6
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDifferentially expressed in asthma. Involved in TCR signalling.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:166


ACCESS NO102137
GENEALOX15
DESCRIPTIONArachidonate 15-lipoxygenase
NCBI ENTREZ ACCESS NO246
UNIPROT ACCESS NOP16050
ORGANISMHuman
DISEASE PHENOTYPEAllergic asthma
SAMPLEBronchial Biopsy
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in allergic asthma.
GEO_PRIDE_ACCESS_NOGSE41649
REFERENCE19842841
DRUG TARGETBE0000309
MONCLONAL ANTIBODYAnti-15 Lipoxygenase 1 for Rat/Dog/Monkey