BROWSE RESULT OF A
166 Records |
ACCESS NO | 100007 |
GENE | ANXA5 |
DESCRIPTION | Annexin A5 |
NCBI ENTREZ ACCESS NO | 308 |
UNIPROT ACCESS NO | P08758 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
SAMPLE | CD2+ cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | It is involved in stress and wound response. |
GEO_PRIDE_ACCESS_NO | GSE7894 |
REFERENCE | 19001005 |
DRUG TARGET | BE0004149 |
MONCLONAL ANTIBODY | Anti-Annexin V for Human |
Record No:2
ACCESS NO | 100009 |
GENE | ADM |
DESCRIPTION | Adrenomedullin |
NCBI ENTREZ ACCESS NO | 133 |
UNIPROT ACCESS NO | P35318 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
SAMPLE | CD2+ cells |
TECHNIQUES | Microarray and TaqMan Gene Expression Assays |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is involved in wound responsee. |
GEO_PRIDE_ACCESS_NO | GSE7894 |
REFERENCE | 19001005 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:3
ACCESS NO | 100038 |
GENE | ANK3 |
DESCRIPTION | Ankyrin 3 |
NCBI ENTREZ ACCESS NO | 288 |
UNIPROT ACCESS NO | Q12955 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
SAMPLE | CD2+ cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene is upregulated more in high SEC group. |
GEO_PRIDE_ACCESS_NO | GSE7894 |
REFERENCE | 19001005 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Ankyrin G for Mouse/Rat/Human |
Record No:4
ACCESS NO | 100053 |
GENE | ALOX15B |
DESCRIPTION | Arachidonate 15-lipoxygenase type B |
NCBI ENTREZ ACCESS NO | 247 |
UNIPROT ACCESS NO | O15296 |
ORGANISM | Human |
DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | Microarray and qRT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is involved in arachidonic acid/prostagandin metabolism. |
GEO_PRIDE_ACCESS_NO | GSE16032 |
REFERENCE | 19620293 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:5
ACCESS NO | 100054 |
GENE | ALOX5 |
DESCRIPTION | Arachidonate 5-lipoxygenase |
NCBI ENTREZ ACCESS NO | 240 |
UNIPROT ACCESS NO | P09917 |
ORGANISM | Human |
DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | Microarray and qRT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is involved in arachidonic acid/prostagandin metabolism. |
GEO_PRIDE_ACCESS_NO | GSE16032 |
REFERENCE | 19620293 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-5 Lipoxygenase for Mouse/Rat/Human |
Record No:6
ACCESS NO | 100080 |
GENE | ADORA3 |
DESCRIPTION | Adenosine A3 receptor |
NCBI ENTREZ ACCESS NO | 140 |
UNIPROT ACCESS NO | Q6P2N6 |
ORGANISM | Human |
DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | Microarray and qRT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is involved in innate immunity. |
GEO_PRIDE_ACCESS_NO | GSE16032 |
REFERENCE | 19620293 |
DRUG TARGET | BE0000354 |
MONCLONAL ANTIBODY | N/A |
Record No:7
ACCESS NO | 100084 |
GENE | AREG |
DESCRIPTION | Amphiregulin |
NCBI ENTREZ ACCESS NO | 374 |
UNIPROT ACCESS NO | P15514 |
ORGANISM | Human |
DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | Microarray and qRT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is involved in adaptive immunity. |
GEO_PRIDE_ACCESS_NO | GSE16032 |
REFERENCE | 19620293 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Amphiregulin for Human |
Record No:8
ACCESS NO | 100096 |
GENE | ADAMTS2 |
DESCRIPTION | ADAM metallopeptidase with thrombospondin type 1 motif-2 |
NCBI ENTREZ ACCESS NO | 9509 |
UNIPROT ACCESS NO | O95450 |
ORGANISM | Human |
DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | Microarray and qRT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | This gene is associated with inflammation. |
GEO_PRIDE_ACCESS_NO | GSE16032 |
REFERENCE | 19620293 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ADAMTS2 for Rat/Human |
Record No:9
ACCESS NO | 100113 |
GENE | Arg1 |
DESCRIPTION | Arginase 1 |
NCBI ENTREZ ACCESS NO | 11846 |
UNIPROT ACCESS NO | Q61176 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | DNA Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This arginine metabolism is commonly induced by allergens and Th2 cytokines such as IL-4 and IL-13. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19249085 |
DRUG TARGET | BE0000286 |
MONCLONAL ANTIBODY | Anti-liver Arginase for Human |
Record No:10
ACCESS NO | 100121 |
GENE | Adam8 |
DESCRIPTION | A disintegrin and metalloprotease domain 8 |
NCBI ENTREZ ACCESS NO | 11501 |
UNIPROT ACCESS NO | Q05910 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | DNA Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This protease is specifically induced by Th2 cytokines such as IL-4 and IL-13. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19249085 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ADAM8 [EPR14612] for Mouse/Rat/Human |
Record No:11
ACCESS NO | 100125 |
GENE | Atf3 |
DESCRIPTION | Activating transcription factor 3 |
NCBI ENTREZ ACCESS NO | 11910 |
UNIPROT ACCESS NO | Q60765 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | DNA Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is an IL-4 specific host immune responsive gene induced in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19249085 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ATF3 for Human |
Record No:12
ACCESS NO | 100140 |
GENE | Agr2 |
DESCRIPTION | Anterior gradient 2 |
NCBI ENTREZ ACCESS NO | 23795 |
UNIPROT ACCESS NO | O88312 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | DNA Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | This is an IL-13 specific epithelial product induced in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19249085 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-AGR2 + AGR3 for Human |
Record No:13
ACCESS NO | 100142 |
GENE | Aass |
DESCRIPTION | Aminoadipate-semialdehyde synthase |
NCBI ENTREZ ACCESS NO | 30956 |
UNIPROT ACCESS NO | Q99K67 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | DNA Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | This is an IL-13 specific lysine metabolism gene induced in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19249085 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-AASS for Mouse/Human |
Record No:14
ACCESS NO | 100158 |
GENE | AREG |
DESCRIPTION | Amphiregulin |
NCBI ENTREZ ACCESS NO | 374 |
UNIPROT ACCESS NO | P15514 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Amphiregulin for Human |
Record No:15
ACCESS NO | 100174 |
GENE | ASB9 |
DESCRIPTION | Ankyrin repeat and SOCS box-containing 9 |
NCBI ENTREZ ACCESS NO | 140462 |
UNIPROT ACCESS NO | Q96DX5 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is a cell communication protein significantly down regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:16
ACCESS NO | 100202 |
GENE | ADAM8 |
DESCRIPTION | A disintegrin and metalloproteinase domain 8 |
NCBI ENTREZ ACCESS NO | 101 |
UNIPROT ACCESS NO | P78325 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene codes for a metabolic enzyme significantly up regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ADAM8 [EPR14612] for Mouse/Rat/Human |
Record No:17
ACCESS NO | 100205 |
GENE | ABCC3 |
DESCRIPTION | ATP-binding cassette sub-family C member 3 |
NCBI ENTREZ ACCESS NO | 8714 |
UNIPROT ACCESS NO | O15438 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene codes for a metabolic enzyme significantly up regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | BE0001061 |
MONCLONAL ANTIBODY | N/A |
Record No:18
ACCESS NO | 100207 |
GENE | ATP2C2 (KIAA0703) |
DESCRIPTION | Probable calcium-transporting ATPase KIAA0703 |
NCBI ENTREZ ACCESS NO | 9914 |
UNIPROT ACCESS NO | O75185 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene codes for a metabolic enzyme significantly up regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:19
ACCESS NO | 100210 |
GENE | AKR1C3 |
DESCRIPTION | Aldo-keto reductase family 1 - member C3 |
NCBI ENTREZ ACCESS NO | 8644 |
UNIPROT ACCESS NO | P42330 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene codes for a metabolic enzyme significantly down regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | BE0000592 |
MONCLONAL ANTIBODY | Anti-AKR1C3 for Human |
Record No:20
ACCESS NO | 100212 |
GENE | ALPP |
DESCRIPTION | Alkaline phosphatase placental type precursor |
NCBI ENTREZ ACCESS NO | 250 |
UNIPROT ACCESS NO | P05187 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene codes for a metabolic enzyme significantly down regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | BE0000314 |
MONCLONAL ANTIBODY | Anti-ALPPL2 for Human |
Record No:21
ACCESS NO | 100232 |
GENE | ARRDC3 |
DESCRIPTION | Arrestin domain containing 3 |
NCBI ENTREZ ACCESS NO | 57561 |
UNIPROT ACCESS NO | Q96B67 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene is significantly up regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:22
ACCESS NO | 100235 |
GENE | APBB1 |
DESCRIPTION | Amyloid beta (A4) precursor protein-binding B1 |
NCBI ENTREZ ACCESS NO | 322 |
UNIPROT ACCESS NO | O00213 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene is significantly up regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:23
ACCESS NO | 100240 |
GENE | APCDD1 |
DESCRIPTION | Adenomatosis polyposis coli down-regulated 1 |
NCBI ENTREZ ACCESS NO | 147495 |
UNIPROT ACCESS NO | Q8J025 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene is significantly down regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:24
ACCESS NO | 100274 |
GENE | ADAM19 |
DESCRIPTION | ADAM metallopeptidase domain 19 |
NCBI ENTREZ ACCESS NO | 8728 |
UNIPROT ACCESS NO | Q9H013 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
SAMPLE | Primary bronchial epithelial cells |
TECHNIQUES | Affymetrix GeneChip Microarray and qRT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is expressed at higher levels in the asthma samples (P<0.05) and was downregulated by HRV in both groups. It is involved in cell-matrix interactions. |
GEO_PRIDE_ACCESS_NO | GSE13396 |
REFERENCE | 19710636 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SPARC for Rat/Human |
Record No:25
ACCESS NO | 100304 |
GENE | Acvr1 |
DESCRIPTION | Activin receptor type I |
NCBI ENTREZ ACCESS NO | 11477 |
UNIPROT ACCESS NO | P37172 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
SAMPLE | Peripheral blood monocytes |
TECHNIQUES | DNA Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is a cytokine receptor. It has been observed to be down regulated in the present study. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20840155 |
DRUG TARGET | BE0000264 |
MONCLONAL ANTIBODY | Anti-Activin Receptor Type IA for Mouse/Rat/Human |
Record No:26
ACCESS NO | 100322 |
GENE | Agrn |
DESCRIPTION | Agrin |
NCBI ENTREZ ACCESS NO | 25592 |
UNIPROT ACCESS NO | N/A |
ORGANISM | Rat |
DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
SAMPLE | Lung tissue |
TECHNIQUES | Serial analysis of gene expression (SAGE) |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | The expression of agrin was decreased in the SAGE library from asthmatic lung. This suggests that agrin may disperse the aggregation of molecules in the immunological synapse including the T-cell receptor and IgE receptor. |
GEO_PRIDE_ACCESS_NO | GSE2475 |
REFERENCE | 18922145 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Agrin for Mouse/Rat |
Record No:27
ACCESS NO | 100341 |
GENE | Apoe |
DESCRIPTION | Apolipoprotein E |
NCBI ENTREZ ACCESS NO | 11816 |
UNIPROT ACCESS NO | P08226 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma induced chemicals |
SAMPLE | Serum |
TECHNIQUES | 2D DIGE and MALDI-TOF-MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It contributes to the protection against oxidative damage. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20860378 |
DRUG TARGET | BE0001119 |
MONCLONAL ANTIBODY | Anti-Calreticulin [FMC 75] for Mouse/Rat/Human/Monkey |
Record No:28
ACCESS NO | 100352 |
GENE | ALDH3B1 |
DESCRIPTION | B1-transcript variant 2 |
NCBI ENTREZ ACCESS NO | 221 |
UNIPROT ACCESS NO | P43353 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | It is upregulated in asthma exacerbation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19187333 |
DRUG TARGET | BE0000446 |
MONCLONAL ANTIBODY | N/A |
Record No:29
ACCESS NO | 100389 |
GENE | Alb |
DESCRIPTION | Serum albumin |
NCBI ENTREZ ACCESS NO | 11657 |
UNIPROT ACCESS NO | P07724 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
SAMPLE | Broncho Alveolar Lavage (BAL)F |
TECHNIQUES | 2D PAGE andLC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This gene is upregulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20029843 |
DRUG TARGET | BE0000530 |
MONCLONAL ANTIBODY | Anti-Human Serum Albumin antibody for Human |
Record No:30
ACCESS NO | 100392 |
GENE | Arl2 |
DESCRIPTION | ADP-ribosylation factor-like protein 2 |
NCBI ENTREZ ACCESS NO | 56327 |
UNIPROT ACCESS NO | Q9D0J4 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Allergen induced asthma |
SAMPLE | Broncho Alveolar Lavage (BAL)F |
TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This gene is upregulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15378764 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ARL2 for Mouse/Rat/Human |
Record No:31
ACCESS NO | 100395 |
GENE | Anxa1 |
DESCRIPTION | Annexin-1 |
NCBI ENTREZ ACCESS NO | 16952 |
UNIPROT ACCESS NO | P10107 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Allergen induced asthma |
SAMPLE | Broncho Alveolar Lavage (BAL)F |
TECHNIQUES | 2D PAGE and MALDI-TOF-MS followed by immunoblot an |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It inhibits cytosolic phospholipase A2 (cPLA2) but in allergic asthma it undergoes proteolytic degradation. Its downregulation in 2D PAGE was not significant. However I western blot and real time PCR it showed significant downregulation as a result of degradation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15378764 |
DRUG TARGET | BE0000422 |
MONCLONAL ANTIBODY | Anti-Annexin A1 for Human |
Record No:32
ACCESS NO | 100418 |
GENE | ATP5H |
DESCRIPTION | ATP synthase- H+ transporting- mitochondrial F0 complex subunit d isoform a |
NCBI ENTREZ ACCESS NO | 10476 |
UNIPROT ACCESS NO | O75947 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | bronchial epithelial cells stimulated with TGF bet |
TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It is upregulated in asthma inflammation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20219718 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ATP5H for Mouse/Rat/Human |
Record No:33
ACCESS NO | 100449 |
GENE | ANXA3 |
DESCRIPTION | Annexin A3 |
NCBI ENTREZ ACCESS NO | 306 |
UNIPROT ACCESS NO | P12429 |
ORGANISM | Human |
DISEASE PHENOTYPE | Severe asthma |
SAMPLE | CD8 + T cells |
TECHNIQUES | Microarray and Real time Q-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is upregulated in asthma inflammation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21917308 |
DRUG TARGET | BE0003201 |
MONCLONAL ANTIBODY | Anti-Annexin A3 for Human |
Record No:34
ACCESS NO | 100464 |
GENE | AXIN2 |
DESCRIPTION | Axin 2 |
NCBI ENTREZ ACCESS NO | 8313 |
UNIPROT ACCESS NO | Q9Y2T1 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Airway smooth muscle cell (ASM) line |
TECHNIQUES | Microarray and qPCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is induced in airway smooth muscle cell after glucocorticoid treatment. |
GEO_PRIDE_ACCESS_NO | GSE3946 |
REFERENCE | 21257922 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:35
ACCESS NO | 100479 |
GENE | ARG1 |
DESCRIPTION | Arginase-1 |
NCBI ENTREZ ACCESS NO | 383 |
UNIPROT ACCESS NO | P05089 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis and eczema |
SAMPLE | Skin tapings |
TECHNIQUES | nano-HPLC-MS/MS (ion trap) |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It produces urea from L-arginine. Urea is a hygroscopic component of the natural moisturizing factor of human skin. This gene is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient without eczema herpeticum . |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21211653 |
DRUG TARGET | BE0000286 |
MONCLONAL ANTIBODY | Anti-liver Arginase for Mouse |
Record No:36
ACCESS NO | 100488 |
GENE | ALB |
DESCRIPTION | Albumin |
NCBI ENTREZ ACCESS NO | 213 |
UNIPROT ACCESS NO | P02768 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis |
SAMPLE | Nasal fluid |
TECHNIQUES | LC-MS/MS and ELISA |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | This protein is identified as s potential markers for treatment response to Glucocorticoids in allergic rhinitis. It is a component of acute phase response pathway. Its expression decrease following GC treatment as estimated in LC-MS/MS but not significantly in ELISA assay. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21887273 |
DRUG TARGET | BE0000530 |
MONCLONAL ANTIBODY | N/A |
Record No:37
ACCESS NO | 100489 |
GENE | A2M |
DESCRIPTION | alpha-2-macroglobulin |
NCBI ENTREZ ACCESS NO | 2 |
UNIPROT ACCESS NO | P01023 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of glucocorticoid treatment |
SAMPLE | Bronchial biopsy |
TECHNIQUES | iTRAQ labelling followed by nano LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It is a type of cytokione present in extracellular space. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21939520 |
DRUG TARGET | BE0000910 |
MONCLONAL ANTIBODY | Anti-alpha 2 Macroglobulin for Human |
Record No:38
ACCESS NO | 100490 |
GENE | ALDOA |
DESCRIPTION | aldolase A fructose-bisphosphate |
NCBI ENTREZ ACCESS NO | 226 |
UNIPROT ACCESS NO | P04075 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of glucocorticoid treatment |
SAMPLE | Bronchial biopsy |
TECHNIQUES | iTRAQ labelling followed by nano LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This gene shows down regulation of protein expression after budesonide treatment on asthmatics. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21939520 |
DRUG TARGET | BE0001683 |
MONCLONAL ANTIBODY | Anti-Aldolase for Human |
Record No:39
ACCESS NO | 100491 |
GENE | ATP5B |
DESCRIPTION | ATP synthase H+ transporting mitochondrial F1 complex-beta polypeptide |
NCBI ENTREZ ACCESS NO | 506 |
UNIPROT ACCESS NO | P06576 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of glucocorticoid treatment |
SAMPLE | Bronchial biopsy |
TECHNIQUES | iTRAQ labelling followed by nano LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This gene shows down regulation of protein expression after budesonide treatment on asthmatics. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21939520 |
DRUG TARGET | BE0003841 |
MONCLONAL ANTIBODY | Anti-ATPB [3D5] for Mouse/Rat/Human |
Record No:40
ACCESS NO | 100496 |
GENE | ANXA5 |
DESCRIPTION | Annexin A5 |
NCBI ENTREZ ACCESS NO | 308 |
UNIPROT ACCESS NO | P08758 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of glucocorticoid treatment |
SAMPLE | Bronchial biopsy |
TECHNIQUES | iTRAQ labelling followed by nano LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is involved in fibrosis and inflammation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21939520 |
DRUG TARGET | BE0004149 |
MONCLONAL ANTIBODY | Anti-Annexin V for Human |
Record No:41
ACCESS NO | 100527 |
GENE | ARG1 |
DESCRIPTION | Arginase 1 |
NCBI ENTREZ ACCESS NO | 11846 |
UNIPROT ACCESS NO | Q61176 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Macrophages from Broncho Alveolar Lavage (BAL) and |
TECHNIQUES | Illumina gene chip microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is produced by the M2 macrophages present in the airway lumen. This protein along with chitinases and other chemokines may play an important role in leukocyte migration into asthmatic airways. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 23685352 |
DRUG TARGET | BE0000286 |
MONCLONAL ANTIBODY | N/A |
Record No:42
ACCESS NO | 100534 |
GENE | Adam8 |
DESCRIPTION | ADAM metallopeptidase domain 8 |
NCBI ENTREZ ACCESS NO | 11501 |
UNIPROT ACCESS NO | Q05910 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Acute and chronic asthma |
SAMPLE | Tissue from left lung |
TECHNIQUES | Affymetrix gene chip cDNA microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18087161 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ADAM8 for Human |
Record No:43
ACCESS NO | 100547 |
GENE | Alox15 |
DESCRIPTION | Arachidonate 15-lipoxygenase |
NCBI ENTREZ ACCESS NO | 11687 |
UNIPROT ACCESS NO | P39654 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Tissue from bronchial biopsy |
TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | It s new potential candidate of asthma pathogenesis. |
GEO_PRIDE_ACCESS_NO | GSE15823 |
REFERENCE | 15038835 |
DRUG TARGET | BE0000309 |
MONCLONAL ANTIBODY | Anti-15 Lipoxygenase 1 for Human/Rat/Monkey |
Record No:44
ACCESS NO | 100553 |
GENE | Aatf (Trb) |
DESCRIPTION | T cell receptor beta locus |
NCBI ENTREZ ACCESS NO | 56321 |
UNIPROT ACCESS NO | Q9JKX4 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Tissue from bronchial biopsy |
TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | downregulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | GSE15823 |
REFERENCE | 15038835 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-AATF for Human |
Record No:45
ACCESS NO | 100600 |
GENE | APOB |
DESCRIPTION | Apolipoprotein B |
NCBI ENTREZ ACCESS NO | 338 |
UNIPROT ACCESS NO | P04114 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Broncho Alveolar Lavage (BAL)F |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Upregulated after allergen challenge. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-APOBEC for Mouse/Rat/Human |
Record No:46
ACCESS NO | 100601 |
GENE | APOA1 |
DESCRIPTION | Apolipoprotein A-I |
NCBI ENTREZ ACCESS NO | 335 |
UNIPROT ACCESS NO | P02647 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Broncho Alveolar Lavage (BAL)F |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Upregulated after allergen challenge. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Apolipoprotein A1 for Human |
Record No:47
ACCESS NO | 100606 |
GENE | ACE |
DESCRIPTION | Angiotensinogen |
NCBI ENTREZ ACCESS NO | 1636 |
UNIPROT ACCESS NO | P12821 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Broncho Alveolar Lavage (BAL)F |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It is a serum protein and upregulated after allergen challenge. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0000221 |
MONCLONAL ANTIBODY | Anti-Angiotensin converting enzyme 1 for Human/Mouse/Rat |
Record No:48
ACCESS NO | 100612 |
GENE | ACSL3 |
DESCRIPTION | acyl-CoA synthetase long-chain family member 3 |
NCBI ENTREZ ACCESS NO | 2181 |
UNIPROT ACCESS NO | O95573 |
ORGANISM | Human |
DISEASE PHENOTYPE | Childhood asthma |
SAMPLE | Umbilical cord white blood cells |
TECHNIQUES | Methylation specific PCR |
OMICS | Epigenetics |
STUDY | Low Throughput |
COMMENTS | Methylation of the ACSL3 5'-CGI is significantly associated with asthma in children. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19221603 |
DRUG TARGET | BE0001093 |
MONCLONAL ANTIBODY | N/A |
Record No:49
ACCESS NO | 100620 |
GENE | ARG1 |
DESCRIPTION | Arginase 1 |
NCBI ENTREZ ACCESS NO | 383 |
UNIPROT ACCESS NO | P05089 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Buccal mucosal cells |
TECHNIQUES | Pyrosequencing |
OMICS | Epigenetics |
STUDY | Low Throughput |
COMMENTS | DNA methylation at the promoter of Arg1 is associated with exhaled nitric oxide- a well known biomarker of airway inflammation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21512169 |
DRUG TARGET | BE0000286 |
MONCLONAL ANTIBODY | N/A |
Record No:50
ACCESS NO | 100621 |
GENE | ARG2 |
DESCRIPTION | Arginase 2 |
NCBI ENTREZ ACCESS NO | 384 |
UNIPROT ACCESS NO | P78540 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Buccal mucosal cells |
TECHNIQUES | Pyrosequencing |
OMICS | Epigenetics |
STUDY | Low Throughput |
COMMENTS | Difference in DNA methylation at the promoter of Arg1 controls the exhaled nitric oxide. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21512169 |
DRUG TARGET | BE0000758 |
MONCLONAL ANTIBODY | Anti-ARG2 for Human/Rat |
Record No:51
ACCESS NO | 100622 |
GENE | ALOX12 |
DESCRIPTION | arachidonate 12-lipoxygenase |
NCBI ENTREZ ACCESS NO | 239 |
UNIPROT ACCESS NO | P18054 |
ORGANISM | Human |
DISEASE PHENOTYPE | Childhood asthma |
SAMPLE | cord blood DNA |
TECHNIQUES | Pyrosequencing |
OMICS | Epigenetics |
STUDY | Low Throughput |
COMMENTS | Hypomethylation at two CpGs of ALOX12 was significantly associated with persistent wheezing. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 22920181 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:52
ACCESS NO | 100627 |
GENE | APOH |
DESCRIPTION | Apolipoprotein H |
NCBI ENTREZ ACCESS NO | 350 |
UNIPROT ACCESS NO | P02749 |
ORGANISM | Human |
DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
SAMPLE | Nasal fluid |
TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Part of the acute phase response pathway and significantly decreased after Glucocorticoid treatment. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21887273 |
DRUG TARGET | BE0002854 |
MONCLONAL ANTIBODY | Anti-Apolipoprotein H for Rat/Human |
Record No:53
ACCESS NO | 100629 |
GENE | A2M |
DESCRIPTION | Alpha-2-macroglobulin |
NCBI ENTREZ ACCESS NO | 2 |
UNIPROT ACCESS NO | P01023 |
ORGANISM | Human |
DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
SAMPLE | Nasal fluid |
TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Decreased after glucocorticoid treatment. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21887273 |
DRUG TARGET | BE0000910 |
MONCLONAL ANTIBODY | Anti-alpha 2 Macroglobulin for Human |
Record No:54
ACCESS NO | 100630 |
GENE | APOA1 |
DESCRIPTION | Apolipoprotein A-I |
NCBI ENTREZ ACCESS NO | 335 |
UNIPROT ACCESS NO | P02647 |
ORGANISM | Human |
DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
SAMPLE | Nasal fluid |
TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Enriched in acute phase response pathway. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21887273 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Apolipoprotein A I for Human |
Record No:55
ACCESS NO | 100662 |
GENE | A2M |
DESCRIPTION | Alpha-2-macroglobulin |
NCBI ENTREZ ACCESS NO | 2 |
UNIPROT ACCESS NO | P01023 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Plasma proteins |
TECHNIQUES | MALDI Tof |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Interacts and captures any proteinases which are encountered as foreign proteins thus providing a humoral defense barrier against pathogens. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21471098 |
DRUG TARGET | BE0000910 |
MONCLONAL ANTIBODY | Anti-alpha 2 Macroglobulin for Human |
Record No:56
ACCESS NO | 100665 |
GENE | Anxa6 |
DESCRIPTION | Annexin A 6 |
NCBI ENTREZ ACCESS NO | 11749 |
UNIPROT ACCESS NO | P14824 |
ORGANISM | BALB/c Mouse |
DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
SAMPLE | Lung tissue |
TECHNIQUES | MALDI Tof and Western Blotting |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Plays a role in calcium handling in smooth muscles and may take part in smooth muscle hyperresponsiveness during asthma.Upregulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21751807 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Annexin VI for Human |
Record No:57
ACCESS NO | 100668 |
GENE | Apoa1 |
DESCRIPTION | Apolipoprotein A1 |
NCBI ENTREZ ACCESS NO | 11806 |
UNIPROT ACCESS NO | Q00623 |
ORGANISM | BALB/c Mouse |
DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
SAMPLE | Lung tissue |
TECHNIQUES | MALDI Tof and ELISA |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Downregulated in asthma. May be involved in removing pro-inflammatory lipids which helps to reduce asthma phenotype. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21751807 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Apolipoprotein A I for Human |
Record No:58
ACCESS NO | 100680 |
GENE | Actb |
DESCRIPTION | Actin cytoplasmic 1 |
NCBI ENTREZ ACCESS NO | 11461 |
UNIPROT ACCESS NO | P60710 |
ORGANISM | BALB/c Mouse |
DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
SAMPLE | Lung tissue |
TECHNIQUES | MALDI Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Downregulated in allergen induced asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21751807 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-beta Actin for Mouse/Rat/Human |
Record No:59
ACCESS NO | 100682 |
GENE | Acadvl |
DESCRIPTION | Very long-chain specific acyl-CoA dehydrogenase |
NCBI ENTREZ ACCESS NO | 11370 |
UNIPROT ACCESS NO | P50544 |
ORGANISM | BALB/c Mouse |
DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
SAMPLE | Lung tissue |
TECHNIQUES | MALDI Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Downregulated in allergen induced asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21751807 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ACADVL for Human/Cow/Rat/Mouse |
Record No:60
ACCESS NO | 100718 |
GENE | APOH |
DESCRIPTION | Apolipoprotein H |
NCBI ENTREZ ACCESS NO | 350 |
UNIPROT ACCESS NO | P02749 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis treatment with glucocorticoid |
SAMPLE | Nasal lavage fluid |
TECHNIQUES | iTRAQ based proteomics nano LC MS/MS gene expressi |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Acute phase response signalling protein found in nasal polyps. Downregulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20659080 |
DRUG TARGET | BE0002854 |
MONCLONAL ANTIBODY | N/A |
Record No:61
ACCESS NO | 100723 |
GENE | APOE |
DESCRIPTION | apolipoprotein E |
NCBI ENTREZ ACCESS NO | 348 |
UNIPROT ACCESS NO | P02649 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Blood plasma |
TECHNIQUES | MALDI TOF MS and LC-MS/MS and Western Blot |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Essential component of plasma lipoproteins. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19116453 |
DRUG TARGET | BE0001119 |
MONCLONAL ANTIBODY | Anti-Apolipoprotein E for Mouse/Human/Zebrafish |
Record No:62
ACCESS NO | 100736 |
GENE | ALB |
DESCRIPTION | Serum albumin |
NCBI ENTREZ ACCESS NO | 213 |
UNIPROT ACCESS NO | P02768 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma challenged with inhaled allergens |
SAMPLE | Blood plasma |
TECHNIQUES | 2D gel and MALDI-TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19076930 |
DRUG TARGET | BE0000530 |
MONCLONAL ANTIBODY | Anti-Human Serum Albumin for Human |
Record No:63
ACCESS NO | 100737 |
GENE | APOE |
DESCRIPTION | Apolipoprotein - E3 |
NCBI ENTREZ ACCESS NO | 348 |
UNIPROT ACCESS NO | P02649 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma challenged with inhaled allergens |
SAMPLE | Blood plasma |
TECHNIQUES | 2D gel and MALDI-TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Upregulated in immediate phase reaction of allergic patients. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19076930 |
DRUG TARGET | BE0001119 |
MONCLONAL ANTIBODY | Anti-Apolipoprotein E for Mouse/Human/Zebrafish |
Record No:64
ACCESS NO | 100752 |
GENE | Atf5 |
DESCRIPTION | Activating transcription factor 5 |
NCBI ENTREZ ACCESS NO | 107503 |
UNIPROT ACCESS NO | O70191 |
ORGANISM | balb C mice |
DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
SAMPLE | Periferal blood monocytes |
TECHNIQUES | Microarray (agilent) |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated in fungal allergen challenge.Selected based on fold change. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20840155 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ATF5 for Human |
Record No:65
ACCESS NO | 100788 |
GENE | Agr2 |
DESCRIPTION | Arginase2 |
NCBI ENTREZ ACCESS NO | 23795 |
UNIPROT ACCESS NO | O88312 |
ORGANISM | BALB/c Mouse |
DISEASE PHENOTYPE | Acute and chronic asthma |
SAMPLE | Lung Tissue |
TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Encodes a protein expressed in mucous secreting cells and is upregulated in mouse model of asthma both during long as well as short term. allergen exposure |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19028979 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Arg2 for Rat/Dog/Human |
Record No:66
ACCESS NO | 100789 |
GENE | Agr1 |
DESCRIPTION | Arginase1 |
NCBI ENTREZ ACCESS NO | 11846 |
UNIPROT ACCESS NO | Q61176 |
ORGANISM | BALB/c Mouse |
DISEASE PHENOTYPE | Acute and chronic asthma |
SAMPLE | Lung Tissue |
TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Upregulated in asthma. Produced by immune and epithelial cells. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19028979 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:67
ACCESS NO | 100933 |
GENE | Ankrd10 |
DESCRIPTION | Ankyrin repeat domain 10 |
NCBI ENTREZ ACCESS NO | 102334 |
UNIPROT ACCESS NO | Q99LW0 |
ORGANISM | BALB/C mice |
DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
SAMPLE | Mesenteric lymph node |
TECHNIQUES | cDNA microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated after induction with food allergens. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21211037 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:68
ACCESS NO | 100939 |
GENE | Apoa4 |
DESCRIPTION | Apolipoprotein A-IV |
NCBI ENTREZ ACCESS NO | 11808 |
UNIPROT ACCESS NO | P06728 |
ORGANISM | BALB/C mice |
DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
SAMPLE | Mesenteric lymph node |
TECHNIQUES | cDNA microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Downregulated after induction with food allergen challenge. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21211037 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-APOA4 for Human |
Record No:69
ACCESS NO | 100942 |
GENE | Agr2 |
DESCRIPTION | Anterior gradient 2 |
NCBI ENTREZ ACCESS NO | 23795 |
UNIPROT ACCESS NO | O88312 |
ORGANISM | BALB/C mice |
DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
SAMPLE | Mesenteric lymph node |
TECHNIQUES | cDNA microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Downregulated after induction with food allergen challenge. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21211037 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Anterior Gradient 2 for Rat/Human |
Record No:70
ACCESS NO | 100945 |
GENE | Alox12 |
DESCRIPTION | Arachidonate 12-lipoxygenase |
NCBI ENTREZ ACCESS NO | 11684 |
UNIPROT ACCESS NO | P39655 |
ORGANISM | balb/c mice |
DISEASE PHENOTYPE | Epithelial injury in Asthma |
SAMPLE | Broncho Alveolar Lavage (BALF) fluid |
TECHNIQUES | Western blot and ELISA |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Causes epithelial injury in asthma pathogenesis. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 23528921 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:71
ACCESS NO | 100951 |
GENE | AGR2 |
DESCRIPTION | Anterior gradient 2 |
NCBI ENTREZ ACCESS NO | 10551 |
UNIPROT ACCESS NO | O95994 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Trachea section |
TECHNIQUES | immunofloresence immunoblotting RT PCR |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Involved in Mucin production in asthmatic airways. Upregulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 22403803 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Anterior Gradient 2 for Rat/Human |
Record No:72
ACCESS NO | 100963 |
GENE | ADRB2 |
DESCRIPTION | 2-adrenergic receptor |
NCBI ENTREZ ACCESS NO | 154 |
UNIPROT ACCESS NO | P07550 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and risk of Long Acting Beta Agonist (LABA) treatment |
SAMPLE | genomic DNA |
TECHNIQUES | sequencing and SNP typing |
OMICS | Genomics |
STUDY | Low Throughput |
COMMENTS | A 25 bp promoter polynucleotide insertion at 376 ins and Ile 164 allele are two variants of ADRB2 in asthma patients. These variants account for adverse events during LABA therapy. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24621682 |
DRUG TARGET | BE0000694 |
MONCLONAL ANTIBODY | N/A |
Record No:73
ACCESS NO | 100998 |
GENE | ALPL |
DESCRIPTION | Alkaline phosphatase (liver/bone/kidney) |
NCBI ENTREZ ACCESS NO | 249 |
UNIPROT ACCESS NO | P05186 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
SAMPLE | Sputum |
TECHNIQUES | Microarray and qPCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is a biomarker to discriminate eosinophilic asthma from other asthmatic phenotype. It shows highest expression in neutrophilic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24582314 |
DRUG TARGET | BE0003546 |
MONCLONAL ANTIBODY | Anti-Alkaline Phosphatase for Human |
Record No:74
ACCESS NO | 101026 |
GENE | Adh5 (GSNOR) |
DESCRIPTION | S-nitrosoglutathione reductase |
NCBI ENTREZ ACCESS NO | 11532 |
UNIPROT ACCESS NO | P28474 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Broncho Alveolar Lavage (BALF) and plasma |
TECHNIQUES | Biomarker immunoassay and Tracheal ring bioassay |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Administration of GSNOR inhibitor N6022 results in attenuation of both bronchoconstriction and inflammation of asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24405692 |
DRUG TARGET | BE0000009 |
MONCLONAL ANTIBODY | Anti-ADH5 [EPR12886(B)] for Mouse/Rat/Human |
Record No:75
ACCESS NO | 101029 |
GENE | ASAH1 |
DESCRIPTION | Acid ceramidase |
NCBI ENTREZ ACCESS NO | 427 |
UNIPROT ACCESS NO | Q13510 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic eczema (AE) |
SAMPLE | Vernix |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is strongly upregulated in atopic eczema. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24205894 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ASAH1 for Human |
Record No:76
ACCESS NO | 101037 |
GENE | ALAD |
DESCRIPTION | Delta-aminolevulinic acid dehydratase |
NCBI ENTREZ ACCESS NO | 210 |
UNIPROT ACCESS NO | P13716 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic eczema (AE) |
SAMPLE | Vernix |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is strongly upregulated in atopic eczema. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24205894 |
DRUG TARGET | BE0000050 |
MONCLONAL ANTIBODY | Anti-ALAD for Human |
Record No:77
ACCESS NO | 101057 |
GENE | APOH (Apo H) |
DESCRIPTION | Apolipoprotein H |
NCBI ENTREZ ACCESS NO | 350 |
UNIPROT ACCESS NO | P02749 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and aspirin tolerance |
SAMPLE | Plasma |
TECHNIQUES | 2DE and MALDI-TOF/TOF and ELISA |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Expression of this protein is decreased in Aspirin-exacerbated respiratory disease (AERD) as compared to aspirin-tolerant asthma (ATA). |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24120690 |
DRUG TARGET | BE0002854 |
MONCLONAL ANTIBODY | Anti-Apolipoprotein H for Rat/Human |
Record No:78
ACCESS NO | 101159 |
GENE | ANXA1 |
DESCRIPTION | Annexin-1 |
NCBI ENTREZ ACCESS NO | 301 |
UNIPROT ACCESS NO | P04083 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
TECHNIQUES | 2D-DIGE and qPCR |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | This gene is over expressed after dexamethasone treatment. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 22464673 |
DRUG TARGET | BE0000422 |
MONCLONAL ANTIBODY | Anti-Annexin A1 for Human |
Record No:79
ACCESS NO | 101189 |
GENE | ALB |
DESCRIPTION | Human serum albumin |
NCBI ENTREZ ACCESS NO | 213 |
UNIPROT ACCESS NO | P02768 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of toluene diisocyanate (TDI) |
SAMPLE | Serum |
TECHNIQUES | Multiplexed tandem mass spectrometry and western b |
OMICS | Proteomics |
STUDY | Low Throughput |
COMMENTS | Albumin has been identified as a major reaction target for TDI in vivo and TDI–albumin reaction products have been proposed to serve as exposure biomarkers and to act as asthmagens. Vapor phase TDI was found to react with human albumin in a dose-dependent manner with up to 18 potential sites of conjugation of which the most susceptible being Lys351 and the dilysine site Lys413–414. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 22206939 |
DRUG TARGET | BE0000530 |
MONCLONAL ANTIBODY | Anti-Human Serum Albumin for Human |
Record No:80
ACCESS NO | 101192 |
GENE | ADIPOQ |
DESCRIPTION | adiponectin |
NCBI ENTREZ ACCESS NO | 9370 |
UNIPROT ACCESS NO | Q15848 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and obesity |
SAMPLE | Serum |
TECHNIQUES | Immunoassay |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | The adipocytes are the most important source of adiponectin ans its serum levels are markedly decreased in individuals with visceral obesity. Interdisciplinary therapy resulted in increase from 4 to 5.1. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 22170805 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Adiponectin [19F1] for Mouse/Rat/Human |
Record No:81
ACCESS NO | 101197 |
GENE | AKR1B1 |
DESCRIPTION | Aldose reductase |
NCBI ENTREZ ACCESS NO | 231 |
UNIPROT ACCESS NO | P15121 |
ORGANISM | Human |
DISEASE PHENOTYPE | Food allergy |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 22091390 |
DRUG TARGET | BE0000747 |
MONCLONAL ANTIBODY | N/A |
Record No:82
ACCESS NO | 101258 |
GENE | Akt1 (Akt) |
DESCRIPTION | Thymoma viral proto-oncogene 1 |
NCBI ENTREZ ACCESS NO | 11651 |
UNIPROT ACCESS NO | P31750 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
SAMPLE | Lung tissue |
TECHNIQUES | Immunoblot |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Artesunate markedly inhibited the EGF-induced phosphorylation of Akt. Thus EGF induced activation of inflammatory PI3K/Akt signaling pathway is suppressed. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21695271 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-AKT1 for Mouse/Human |
Record No:83
ACCESS NO | 101267 |
GENE | ADIPOQ |
DESCRIPTION | adiponectin |
NCBI ENTREZ ACCESS NO | 9370 |
UNIPROT ACCESS NO | Q15848 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and obesity |
SAMPLE | Broncho Alveolar Lavage (BAL) and plasma |
TECHNIQUES | ELISA |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Increasing BMI was marginally and inversely associated with BAL adiponectin. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21332421 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Adiponectin [19F1] for Mouse/Rat/Human |
Record No:84
ACCESS NO | 101276 |
GENE | ALB |
DESCRIPTION | Serum Albumin |
NCBI ENTREZ ACCESS NO | 213 |
UNIPROT ACCESS NO | P02768 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Blood |
TECHNIQUES | ELISA |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Increased expression in rapid onset asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20832159 |
DRUG TARGET | BE0000530 |
MONCLONAL ANTIBODY | Anti-Human Serum Albumin for Human |
Record No:85
ACCESS NO | 101314 |
GENE | ARHGDIB |
DESCRIPTION | Rho GDP dissociation inhibitor (GDI) beta |
NCBI ENTREZ ACCESS NO | 397 |
UNIPROT ACCESS NO | P52566 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergy(Comparison of Dendritic cell proteome in atopic and non atopic patients) |
SAMPLE | Dendritic cell |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Involved in cellular motility/ negative regulation of cellular adhesion and signal transduction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19494521 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-D4 GDI for Mouse/Rat/Human |
Record No:86
ACCESS NO | 101333 |
GENE | A2M |
DESCRIPTION | Alpha2-macroglobulin |
NCBI ENTREZ ACCESS NO | 2 |
UNIPROT ACCESS NO | P01023 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic airway disease |
SAMPLE | Nasal Lavage |
TECHNIQUES | ELISA |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Increased after nasal allergen challenge. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19400896 |
DRUG TARGET | BE0000910 |
MONCLONAL ANTIBODY | Anti-alpha 2 Macroglobulin for Human |
Record No:87
ACCESS NO | 101334 |
GENE | AMCase |
DESCRIPTION | Chitinase acidic 1 |
NCBI ENTREZ ACCESS NO | 81600 |
UNIPROT ACCESS NO | Q91XA9 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Asthma (Effect of andrographolide on NF kappa beta pathway in asthma) |
SAMPLE | Bronchial Epithelial cells |
TECHNIQUES | RT-PCR |
OMICS | Genomics |
STUDY | Low Throughput |
COMMENTS | Suppressed after andrographolide treatment. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19201922 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:88
ACCESS NO | 101349 |
GENE | ABCA-1 |
DESCRIPTION | ATP-binding cassette A1 |
NCBI ENTREZ ACCESS NO | 313210 |
UNIPROT ACCESS NO | Q80ZB2 |
ORGANISM | Male Brown Norway rats |
DISEASE PHENOTYPE | Asthma (LXR agonist treated rat) |
SAMPLE | Tracheal tissue |
TECHNIQUES | RT-PCR/ELISA |
OMICS | Genomics |
STUDY | Low Throughput |
COMMENTS | mRNA increasedafter LXR agonist treatment. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18768884 |
DRUG TARGET | BE0000119 |
MONCLONAL ANTIBODY | Anti-ABCA1 for Mouse |
Record No:89
ACCESS NO | 101351 |
GENE | ALB |
DESCRIPTION | Albumin |
NCBI ENTREZ ACCESS NO | 213 |
UNIPROT ACCESS NO | P02768 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Exhaled Breath condensate |
TECHNIQUES | ELISA |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Higher in smoking people compared to asthmatics. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18513240 |
DRUG TARGET | BE0000530 |
MONCLONAL ANTIBODY | Anti-Human Serum Albumin for Human |
Record No:90
ACCESS NO | 101353 |
GENE | Arpc4 |
DESCRIPTION | ARP 2/3 complex subunit 5 |
NCBI ENTREZ ACCESS NO | 68089 |
UNIPROT ACCESS NO | P59999 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Chronic Asthma |
SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Involved in cell migration and adhesion. Significantly upregulated by 2 fold. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18594147 |
DRUG TARGET | BE0004254 |
MONCLONAL ANTIBODY | N/A |
Record No:91
ACCESS NO | 101368 |
GENE | Ak1 |
DESCRIPTION | Adenylate kinase 1 |
NCBI ENTREZ ACCESS NO | 11636 |
UNIPROT ACCESS NO | Q9R0Y5 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Chronic Asthma |
SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Involved in cellular metabolism and expressed in chronic asthma mouse model. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18594147 |
DRUG TARGET | BE0001262 |
MONCLONAL ANTIBODY | Anti-Adenylate Kinase 1 for Mouse/Rat/Human |
Record No:92
ACCESS NO | 101376 |
GENE | Apoa1 |
DESCRIPTION | Apolipoprotein A-I |
NCBI ENTREZ ACCESS NO | 11806 |
UNIPROT ACCESS NO | Q00623 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Chronic Asthma |
SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Upregulated in chronic asthma model. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18594147 |
DRUG TARGET | BE0000936 |
MONCLONAL ANTIBODY | Anti-Apolipoprotein A I for Human |
Record No:93
ACCESS NO | 101384 |
GENE | Apcs |
DESCRIPTION | Serum amyloid P component |
NCBI ENTREZ ACCESS NO | 20219 |
UNIPROT ACCESS NO | P12246 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Chronic Asthma |
SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Reduced expression in chronically asthmatic mouse. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18594147 |
DRUG TARGET | BE0001213 |
MONCLONAL ANTIBODY | Anti-Serum Amyloid P for Human |
Record No:94
ACCESS NO | 101394 |
GENE | Anxa3 |
DESCRIPTION | Annexin A3 |
NCBI ENTREZ ACCESS NO | 11745 |
UNIPROT ACCESS NO | O35639 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Chronic Asthma |
SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Elevated in chronically inflammed lungs. Controls Chloride channel activity for mucus production. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18594147 |
DRUG TARGET | BE0003201 |
MONCLONAL ANTIBODY | Anti-Annexin A3 for Human(predicted). |
Record No:95
ACCESS NO | 101395 |
GENE | Anxa5 |
DESCRIPTION | Annexin A5 |
NCBI ENTREZ ACCESS NO | 11747 |
UNIPROT ACCESS NO | P48036 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Chronic Asthma |
SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Elevated in chronically inflammed lungs. Controls Chloride channel activity for mucus production. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18594147 |
DRUG TARGET | BE0004149 |
MONCLONAL ANTIBODY | Anti-Annexin V for Mouse/Rat/Human |
Record No:96
ACCESS NO | 101442 |
GENE | Asprv1 |
DESCRIPTION | Aspartic peptidase retroviral-like 1 |
NCBI ENTREZ ACCESS NO | 67855 |
UNIPROT ACCESS NO | Q09PK2 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated after 3hours and 12 hours of fungal allergen induction in asthmatic mice. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:97
ACCESS NO | 101474 |
GENE | Arid5a |
DESCRIPTION | AT rich interactive domain 5A (MRF1-like) |
NCBI ENTREZ ACCESS NO | 214855 |
UNIPROT ACCESS NO | Q3U108 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated after 3 and 12 hours of fungal allergen challenge in asthmatic mice. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:98
ACCESS NO | 101484 |
GENE | Arg2 |
DESCRIPTION | Arginase 2 |
NCBI ENTREZ ACCESS NO | 11847 |
UNIPROT ACCESS NO | O08691 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray and RT PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Significantly increased after 1 and 18 hour timepoints. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | BE0000758 |
MONCLONAL ANTIBODY | Anti-Arg2 for Human/Rat/Dog |
Record No:99
ACCESS NO | 101519 |
GENE | Adam8 |
DESCRIPTION | A disintegrin and metallopeptidase domain 8 |
NCBI ENTREZ ACCESS NO | 11501 |
UNIPROT ACCESS NO | Q05910 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ADAM8 for Human/Mouse/Rat |
Record No:100
ACCESS NO | 101528 |
GENE | ADIPOQ |
DESCRIPTION | Adiponectin |
NCBI ENTREZ ACCESS NO | 9370 |
UNIPROT ACCESS NO | Q15848 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma rhinoconjunctivitis and eczema |
SAMPLE | EDTA added blood plasma |
TECHNIQUES | ELISA |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Low adiponectin is associated with rhinoconjunctivitis and hay fever in girls and higher prevalence of asthma in general. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18331416 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Adiponectin for Mouse/Rat/Human |
Record No:101
ACCESS NO | 101530 |
GENE | ALB |
DESCRIPTION | Albumin |
NCBI ENTREZ ACCESS NO | 213 |
UNIPROT ACCESS NO | P02768 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Exhaled breath condensate |
TECHNIQUES | ELISA |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Higher in smoking group. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18513240 |
DRUG TARGET | BE0000530 |
MONCLONAL ANTIBODY | Anti-Human Serum Albumin for Human |
Record No:102
ACCESS NO | 101532 |
GENE | ALB |
DESCRIPTION | Albumin |
NCBI ENTREZ ACCESS NO | 213 |
UNIPROT ACCESS NO | P02768 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Venous blood |
TECHNIQUES | ELISA |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Decreased in asthmatics after etanercept administration. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18245148 |
DRUG TARGET | BE0000530 |
MONCLONAL ANTIBODY | Anti-Human Serum Albumin for Human |
Record No:103
ACCESS NO | 101545 |
GENE | AMcase |
DESCRIPTION | Chitinase acidic 1 |
NCBI ENTREZ ACCESS NO | 81600 |
UNIPROT ACCESS NO | Q91XA9 |
ORGANISM | Female Balb/c Mice |
DISEASE PHENOTYPE | Asthma(Effect of Glycogen synthase kinase-3 beta inhibition on asthma) |
SAMPLE | Lung tissue |
TECHNIQUES | RT-PCR |
OMICS | Genomics |
STUDY | Low Throughput |
COMMENTS | It is involved in airway remodelling and inflammation.Upregulated after OVA challenge but downregulated after GSK-3b inhibitor induction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17556716 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:104
ACCESS NO | 101562 |
GENE | AGR2 |
DESCRIPTION | Anterior gradient 2 |
NCBI ENTREZ ACCESS NO | 23795 |
UNIPROT ACCESS NO | O88312 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Interleukin 13 induced gene. Involved in secreted signal transduction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Anterior Gradient 2 for Rat/Human |
Record No:105
ACCESS NO | 101574 |
GENE | ARG1 |
DESCRIPTION | Arginase liver |
NCBI ENTREZ ACCESS NO | 11846 |
UNIPROT ACCESS NO | Q61176 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Involved in metabolism and induced by both OVA challenge and IL 13 induction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | BE0000286 |
MONCLONAL ANTIBODY | Anti-liver Arginase for Human |
Record No:106
ACCESS NO | 101600 |
GENE | Actg2 |
DESCRIPTION | Actin gamma 2 smooth muscle enteric |
NCBI ENTREZ ACCESS NO | 11468 |
UNIPROT ACCESS NO | P63268 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Cytoskeletal protein expressed after IL 13 induction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:107
ACCESS NO | 101612 |
GENE | Acp5 |
DESCRIPTION | Acid phosphatase 5 tartrate resistant |
NCBI ENTREZ ACCESS NO | 11433 |
UNIPROT ACCESS NO | Q05117 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Involved in metabolism and expressed after IL 13 induction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Tartrate Resistant Acid Phosphatase for Human |
Record No:108
ACCESS NO | 101613 |
GENE | Ak2 |
DESCRIPTION | Adenylate kinase 2 |
NCBI ENTREZ ACCESS NO | 11637 |
UNIPROT ACCESS NO | Q9WTP6 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Involved in metabolism and expressed after IL 13 induction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | BE0004477 |
MONCLONAL ANTIBODY | Anti-AK2 for Mouse/Rat/Human |
Record No:109
ACCESS NO | 101620 |
GENE | Armet |
DESCRIPTION | Mesencephalic astrocyte-derived neurotrophic factor |
NCBI ENTREZ ACCESS NO | 74840 |
UNIPROT ACCESS NO | Q3TMX5 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Expressed after IL 13 induction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ARMET for Human |
Record No:110
ACCESS NO | 101642 |
GENE | a-SMA(ACTA2) |
DESCRIPTION | Alpha smooth muscle actin |
NCBI ENTREZ ACCESS NO | 59 |
UNIPROT ACCESS NO | P62736 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Fibroblasts from Broncho Alveolar Lavage (BAL) Flu |
TECHNIQUES | MALDI Tof Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Overexpressed in mild asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16430780 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-alpha smooth muscle Actin for Mouse/Rat/Rabbit/Human |
Record No:111
ACCESS NO | 101653 |
GENE | Arhgdib |
DESCRIPTION | Rho GDP dissociation inhibitor beta |
NCBI ENTREZ ACCESS NO | 11857 |
UNIPROT ACCESS NO | Q61599 |
ORGANISM | Male BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma |
SAMPLE | Lung tissue |
TECHNIQUES | 2D electrophoresis and MALDI Tof Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Upregulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16100447 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-D4 GDI for Mouse/Rat/Human |
Record No:112
ACCESS NO | 101693 |
GENE | ATP2A2 (SARCA2) |
DESCRIPTION | Sarco/endoplasmic reticulum Calcium pump |
NCBI ENTREZ ACCESS NO | 488 |
UNIPROT ACCESS NO | P16615 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Airway smooth muscle cells (ASM) |
TECHNIQUES | Immunochemistry and rela time PCR and cell biology |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | SERCA2 mRNA and protein expression is reduced in ASM cells from subjects with moderately severe asthma. Rises in intracellular calcium following cell surface receptor-induced SR activation or inhibition of SERCA-mediated Calcium re-uptake were attenuated in ASM cells from asthmatics. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19541629 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SERCA2 ATPase [2A7-A1] for Mouse/Rat/Human |
Record No:113
ACCESS NO | 101702 |
GENE | ADIPOQ |
DESCRIPTION | Adiponectin |
NCBI ENTREZ ACCESS NO | 9370 |
UNIPROT ACCESS NO | Q15848 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This growth factor is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Adiponectin [19F1] for Mouse/Rat/Human |
Record No:114
ACCESS NO | 101738 |
GENE | ASAH1 |
DESCRIPTION | N-Acylsphingosine amidohydrolase |
NCBI ENTREZ ACCESS NO | 427 |
UNIPROT ACCESS NO | B1B5P6 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ASAH1 [1A7] for Human |
Record No:115
ACCESS NO | 101742 |
GENE | ADH5 |
DESCRIPTION | Alcohol dehydrogenase class III x chain |
NCBI ENTREZ ACCESS NO | 128 |
UNIPROT ACCESS NO | D6RFE4 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ADH5 [EPR12885(B)] for Mouse/Rat/Human |
Record No:116
ACCESS NO | 101743 |
GENE | ADH1B |
DESCRIPTION | Alcohol dehydrogenase |
NCBI ENTREZ ACCESS NO | 125 |
UNIPROT ACCESS NO | B7ZB36 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0000400 |
MONCLONAL ANTIBODY | Anti-ADH1B [4F12] for rat/Human |
Record No:117
ACCESS NO | 101754 |
GENE | ANG |
DESCRIPTION | Angiogenin (ribonuclease 5) |
NCBI ENTREZ ACCESS NO | 283 |
UNIPROT ACCESS NO | ANG |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0001181 |
MONCLONAL ANTIBODY | Anti-Angiotensin II Type 1 Receptor [1E10-1A9] for Rat/Rabbit/Human |
Record No:118
ACCESS NO | 101758 |
GENE | AZGP1 |
DESCRIPTION | Zinc-alpha-2-glycoprotein |
NCBI ENTREZ ACCESS NO | 563 |
UNIPROT ACCESS NO | P25311 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This local matrix protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0002857 |
MONCLONAL ANTIBODY | N/A |
Record No:119
ACCESS NO | 101772 |
GENE | APCS |
DESCRIPTION | Serum amyloid P-component (SAP) |
NCBI ENTREZ ACCESS NO | 325 |
UNIPROT ACCESS NO | P02743 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This acute phase protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0001213 |
MONCLONAL ANTIBODY | Anti-Serum Amyloid P [EP1018Y] for Human |
Record No:120
ACCESS NO | 101775 |
GENE | APOB |
DESCRIPTION | Apolipoprotein B |
NCBI ENTREZ ACCESS NO | 338 |
UNIPROT ACCESS NO | P04114 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This apolipoprotein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0004845 |
MONCLONAL ANTIBODY | Anti-APOBEC2 [EPR11285(B)] for Human |
Record No:121
ACCESS NO | 101776 |
GENE | APOA4 |
DESCRIPTION | Apolipoprotein A-IV |
NCBI ENTREZ ACCESS NO | 337 |
UNIPROT ACCESS NO | P06727 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This apolipoprotein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-APOA4 [1D4C11] for Human |
Record No:122
ACCESS NO | 101777 |
GENE | APOE |
DESCRIPTION | Apolipoprotein E (apoE) |
NCBI ENTREZ ACCESS NO | 348 |
UNIPROT ACCESS NO | P02649 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This apolipoprotein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0001119 |
MONCLONAL ANTIBODY | Anti-ApoER2 [EPR3326] for Rat/Mouse/Human |
Record No:123
ACCESS NO | 101779 |
GENE | APOH |
DESCRIPTION | Apolipoprotein H (apo-H) |
NCBI ENTREZ ACCESS NO | 350 |
UNIPROT ACCESS NO | J3QRN2 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This apolipoprotein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0002854 |
MONCLONAL ANTIBODY | Anti-Apolipoprotein H [EPR2898(2)] for Rat/Human |
Record No:124
ACCESS NO | 101780 |
GENE | APOL1 |
DESCRIPTION | Apolipoprotein L1 |
NCBI ENTREZ ACCESS NO | 8542 |
UNIPROT ACCESS NO | B1AH96 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This apolipoprotein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Apolipoprotein L 1 [EPR2907(2)] for Human |
Record No:125
ACCESS NO | 101781 |
GENE | APOD |
DESCRIPTION | Apolipoprotein D (apoD) |
NCBI ENTREZ ACCESS NO | 347 |
UNIPROT ACCESS NO | C9JX71 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This apolipoprotein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Apolipoprotein D [EPR2916] for Human |
Record No:126
ACCESS NO | 101782 |
GENE | APOA2 |
DESCRIPTION | Apolipoprotein A-II (apoA-II) |
NCBI ENTREZ ACCESS NO | 336 |
UNIPROT ACCESS NO | Q76EI7 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This apolipoprotein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Apolipoprotein A II [4F3] for Human |
Record No:127
ACCESS NO | 101783 |
GENE | APOM |
DESCRIPTION | Apolipoprotein M (apoM) |
NCBI ENTREZ ACCESS NO | 55937 |
UNIPROT ACCESS NO | Q5SRP5 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This apolipoprotein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0004245 |
MONCLONAL ANTIBODY | Anti-Apolipoprotein M [8F12C6B8] for Human |
Record No:128
ACCESS NO | 101784 |
GENE | APOC1 |
DESCRIPTION | Apolipoprotein C-I (apoC-I) |
NCBI ENTREZ ACCESS NO | 341 |
UNIPROT ACCESS NO | K7EKP1 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This apolipoprotein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Apolipoprotein CI for Human |
Record No:129
ACCESS NO | 101785 |
GENE | APOC2 |
DESCRIPTION | Apolipoprotein C-II (apoC-II) |
NCBI ENTREZ ACCESS NO | 344 |
UNIPROT ACCESS NO | Q6P163 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This apolipoprotein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:130
ACCESS NO | 101786 |
GENE | APOC3 |
DESCRIPTION | Apolipoprotein C-III (apoC-III) |
NCBI ENTREZ ACCESS NO | 345 |
UNIPROT ACCESS NO | B0YIW2 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This apolipoprotein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Apolipoprotein CIII [EP1372Y] for Human |
Record No:131
ACCESS NO | 101787 |
GENE | APOC4 |
DESCRIPTION | Apolipoprotein C-IV (apoC-IV) |
NCBI ENTREZ ACCESS NO | 346 |
UNIPROT ACCESS NO | K7EMC3 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This apolipoprotein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Apolipoprotein CIV for Human |
Record No:132
ACCESS NO | 101793 |
GENE | AMBP |
DESCRIPTION | AMBP protein (#-1 microglycoprotein) |
NCBI ENTREZ ACCESS NO | 259 |
UNIPROT ACCESS NO | P78492 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This serum protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Alpha 1 microglobulin [BN11.10] for Rat/Human |
Record No:133
ACCESS NO | 101796 |
GENE | AHSG |
DESCRIPTION | alpha-2-HS-glycoprotein (Ba-alpha-2-glycoprotein) |
NCBI ENTREZ ACCESS NO | 197 |
UNIPROT ACCESS NO | C9JV77 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This serum protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-AHSG [2H2] for Human |
Record No:134
ACCESS NO | 101806 |
GENE | ARPC4 |
DESCRIPTION | Actin-related protein 2/3 complex subunit 4 |
NCBI ENTREZ ACCESS NO | 10093 |
UNIPROT ACCESS NO | P59998 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This cytoskeletal protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0004254 |
MONCLONAL ANTIBODY | N/A |
Record No:135
ACCESS NO | 101807 |
GENE | ARPC1B |
DESCRIPTION | Actin-related protein 2/3 complex subunit 1B |
NCBI ENTREZ ACCESS NO | 10095 |
UNIPROT ACCESS NO | O15143 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This cytoskeletal protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0004249 |
MONCLONAL ANTIBODY | N/A |
Record No:136
ACCESS NO | 101809 |
GENE | ACTR3 |
DESCRIPTION | Actin-related protein 3 (actin-2) |
NCBI ENTREZ ACCESS NO | 10096 |
UNIPROT ACCESS NO | P61158 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This cytoskeletal protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0004251 |
MONCLONAL ANTIBODY | N/A |
Record No:137
ACCESS NO | 101810 |
GENE | ANXA3 |
DESCRIPTION | Annexin A3 (annexin III) (lipocortin III) |
NCBI ENTREZ ACCESS NO | 306 |
UNIPROT ACCESS NO | P12429 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0003201 |
MONCLONAL ANTIBODY | N/A |
Record No:138
ACCESS NO | 101811 |
GENE | ARF3 |
DESCRIPTION | ADP-ribosylation factor 3 |
NCBI ENTREZ ACCESS NO | 377 |
UNIPROT ACCESS NO | P61204 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:139
ACCESS NO | 101817 |
GENE | ANXA11 |
DESCRIPTION | Annexin A11 (annexin XI) |
NCBI ENTREZ ACCESS NO | 311 |
UNIPROT ACCESS NO | P50995 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:140
ACCESS NO | 101834 |
GENE | ACE |
DESCRIPTION | Angiotensin-converting enzyme (ACE) |
NCBI ENTREZ ACCESS NO | 1636 |
UNIPROT ACCESS NO | P12821 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is down regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0000221 |
MONCLONAL ANTIBODY | N/A |
Record No:141
ACCESS NO | 101840 |
GENE | APOA2 |
DESCRIPTION | Apolipoprotein A-II |
NCBI ENTREZ ACCESS NO | 336 |
UNIPROT ACCESS NO | P02652 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis |
SAMPLE | Nasal mucus |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It showed 9.7 fold upregulation in rhinitis patients. It is involved in lipid metabolism and signaling and are present in high-density lipoproteins and chylomicrons. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24290289 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:142
ACCESS NO | 101841 |
GENE | A2M |
DESCRIPTION | alpha 2-Macroglobulin |
NCBI ENTREZ ACCESS NO | 2 |
UNIPROT ACCESS NO | P01023 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis |
SAMPLE | Nasal mucus |
TECHNIQUES | LC-MS/MS and western blot |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It showed 4.5 fold upregulation in rhinitis patients. It is the only significantly increased antiproteinase in mucus from patients with allergic rhinitis with potential for inhibition of all 4 classes of proteinases. It traps the enzyme and decreases its proteolytic activity for high-weight substrates by hydrolyzing a thioester bond and covalent binding to the protease. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24290289 |
DRUG TARGET | BE0000910 |
MONCLONAL ANTIBODY | N/A |
Record No:143
ACCESS NO | 101842 |
GENE | APOA1 |
DESCRIPTION | Apolipoprotein A-I |
NCBI ENTREZ ACCESS NO | 335 |
UNIPROT ACCESS NO | P02647 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis |
SAMPLE | Nasal mucus |
TECHNIQUES | LC-MS/MS and western blot |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It showed 3.2 fold upregulation in rhinitis patients. It is involved in lipid metabolism and signaling and are present in high-density lipoproteins and chylomicrons. It supresses bacterial growth and acts as an anti-inflammatory agent. Its upregulation in patients with allergic rhinitis could reflect the recurring inflammation of the nasal mucosa in patients with allergic rhinitis. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24290289 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:144
ACCESS NO | 101856 |
GENE | ACVR2A |
DESCRIPTION | Activin A receptor type II |
NCBI ENTREZ ACCESS NO | 92 |
UNIPROT ACCESS NO | P27037 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic Rhinitis induced by pollen allergen |
SAMPLE | Nasal lavage fluids |
TECHNIQUES | Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This anti inflammatory gene showed lower expression levels in patients than in controls. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15836756 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Activin Receptor Type IIA for Mouse/Rat/Human |
Record No:145
ACCESS NO | 101870 |
GENE | APOE |
DESCRIPTION | Apolipoprotein E |
NCBI ENTREZ ACCESS NO | 348 |
UNIPROT ACCESS NO | P02649 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Plasma |
TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF and Immunoblot |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | This protein is down regulated in atopic dermatitis patient. It is suggested that inflammation could impair lipoprotein metabolism and produce a wide variety of changes in the plasma concentrations of lipids and lipoproteins. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19116453 |
DRUG TARGET | BE0001119 |
MONCLONAL ANTIBODY | Anti-ApoER2 for Rat/Human |
Record No:146
ACCESS NO | 101871 |
GENE | APOA1 |
DESCRIPTION | Proapolipoprotein |
NCBI ENTREZ ACCESS NO | 335 |
UNIPROT ACCESS NO | P02647 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Plasma |
TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is up regulated in atopic dermatitis patient. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19116453 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Apolipoprotein A I for Human |
Record No:147
ACCESS NO | 101876 |
GENE | AHCY |
DESCRIPTION | Adenosylhomocysteinase |
NCBI ENTREZ ACCESS NO | 191 |
UNIPROT ACCESS NO | P23526 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Fibroblast |
TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is upregulated in atopic fibroblasts comparative to normal fibroblasts. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15468290 |
DRUG TARGET | BE0001684 |
MONCLONAL ANTIBODY | N/A |
Record No:148
ACCESS NO | 101880 |
GENE | ANXA5 |
DESCRIPTION | Annexin A5 |
NCBI ENTREZ ACCESS NO | 308 |
UNIPROT ACCESS NO | P08758 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Fibroblast |
TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is upregulated in atopic fibroblasts comparative to normal fibroblasts. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15468290 |
DRUG TARGET | BE0004149 |
MONCLONAL ANTIBODY | Anti-Annexin V for Human |
Record No:149
ACCESS NO | 101898 |
GENE | AKT1 |
DESCRIPTION | RAC-a-serine/threonine kinase |
NCBI ENTREZ ACCESS NO | 207 |
UNIPROT ACCESS NO | P31749 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Peripheral blood eosinophils |
TECHNIQUES | 2DE-PAGE and MALDI-TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15832365 |
DRUG TARGET | BE0000428 |
MONCLONAL ANTIBODY | Anti-AKT1 (phospho S473) for Mouse/Rat/Human |
Record No:150
ACCESS NO | 101899 |
GENE | ARIH1 |
DESCRIPTION | Ariadne-1 protein homologue (ARI-1) |
NCBI ENTREZ ACCESS NO | 25820 |
UNIPROT ACCESS NO | Q9Y4X5 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Peripheral blood eosinophils |
TECHNIQUES | 2DE-PAGE and MALDI-TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15832365 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:151
ACCESS NO | 101912 |
GENE | ACADVL |
DESCRIPTION | Acyl-CoA dehydrogenase |
NCBI ENTREZ ACCESS NO | 37 |
UNIPROT ACCESS NO | P49748 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Peripheral blood eosinophils |
TECHNIQUES | 2DE-PAGE and MALDI-TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15832365 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ACADVL for Mouse/Rat/Human |
Record No:152
ACCESS NO | 101916 |
GENE | ARFGAP3 |
DESCRIPTION | ADP-ribosylation factor GTPase-activating protein 3 |
NCBI ENTREZ ACCESS NO | 26286 |
UNIPROT ACCESS NO | Q9NP61 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Peripheral blood eosinophils |
TECHNIQUES | 2DE-PAGE and MALDI-TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15832365 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:153
ACCESS NO | 101917 |
GENE | ACTB |
DESCRIPTION | Actin |
NCBI ENTREZ ACCESS NO | 396526 |
UNIPROT ACCESS NO | P60706 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Peripheral blood eosinophils |
TECHNIQUES | 2DE-PAGE and MALDI-TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15832365 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-beta Actin for Mouse/Rat/Human |
Record No:154
ACCESS NO | 101922 |
GENE | AP2M1 |
DESCRIPTION | Plasma membrane adaptor AP-2 protein |
NCBI ENTREZ ACCESS NO | 1173 |
UNIPROT ACCESS NO | Q96CW1 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Peripheral blood eosinophils |
TECHNIQUES | 2DE-PAGE and MALDI-TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15832365 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-AP2M1 for Mouse/Rat/Human |
Record No:155
ACCESS NO | 101934 |
GENE | ATM |
DESCRIPTION | Serine-protein kinase ATM (Ataxia telangiectasia mutated) |
NCBI ENTREZ ACCESS NO | 472 |
UNIPROT ACCESS NO | Q13315 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Peripheral blood eosinophils |
TECHNIQUES | 2DE-PAGE and MALDI-TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15832365 |
DRUG TARGET | BE0004874 |
MONCLONAL ANTIBODY | Anti-ATM for Mouse/Rat/Human |
Record No:156
ACCESS NO | 101950 |
GENE | ALDH3B1 |
DESCRIPTION | B1 transcript variant 2 |
NCBI ENTREZ ACCESS NO | 221 |
UNIPROT ACCESS NO | P43353 |
ORGANISM | Human(Asthmatic children) |
DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
SAMPLE | Peripheral Blood Mononuclear Cells |
TECHNIQUES | Microarray and RT-PCR |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated in asthmatic children. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19187333 |
DRUG TARGET | BE0000446 |
MONCLONAL ANTIBODY | N/A |
Record No:157
ACCESS NO | 101981 |
GENE | ARHGAP5 |
DESCRIPTION | Rho GTPase activating protein 5 |
NCBI ENTREZ ACCESS NO | 394 |
UNIPROT ACCESS NO | Q13017 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and allergic rhinitis |
SAMPLE | Epithelial cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Downregulated in patients with allergic rhinitis with or without asthma in the upper airways. |
GEO_PRIDE_ACCESS_NO | GSE51392 |
REFERENCE | 24475887 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-RhoGAP for Mouse/Rat/Human |
Record No:158
ACCESS NO | 101982 |
GENE | ANKH |
DESCRIPTION | ANKH inorganic pyrophosphate transport regulator |
NCBI ENTREZ ACCESS NO | 56172 |
UNIPROT ACCESS NO | Q9HCJ1 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and allergic rhinitis |
SAMPLE | Epithelial cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Downregulated in patients with allergic rhinitis with or without asthma in the upper airways. |
GEO_PRIDE_ACCESS_NO | GSE51392 |
REFERENCE | 24475887 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ANKH for Mouse/Rat/Human |
Record No:159
ACCESS NO | 101987 |
GENE | AHNAK |
DESCRIPTION | AHNAK nucleoprotein |
NCBI ENTREZ ACCESS NO | 79026 |
UNIPROT ACCESS NO | Q09666 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and allergic rhinitis |
SAMPLE | Epithelial cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Downregulated in patients with allergic rhinitis with or without asthma in the upper airways. |
GEO_PRIDE_ACCESS_NO | GSE51392 |
REFERENCE | 24475887 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-AHNAK for Mouse/Human |
Record No:160
ACCESS NO | 102023 |
GENE | AKAP12 |
DESCRIPTION | A kinase (PRKA) anchor protein 12 |
NCBI ENTREZ ACCESS NO | 9590 |
UNIPROT ACCESS NO | Q02952 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis and asthma |
SAMPLE | Bronchial epithelial cells |
TECHNIQUES | Microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Highly expressed in patients with allergic rhinitis and asthma.(Data in supplimentary table). |
GEO_PRIDE_ACCESS_NO | GSE44037 |
REFERENCE | 24282527 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-AKAP12 for Human |
Record No:161
ACCESS NO | 102048 |
GENE | AHI1 |
DESCRIPTION | Abelson helper integration site 1 |
NCBI ENTREZ ACCESS NO | 54806 |
UNIPROT ACCESS NO | Q8N157 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis and asthma |
SAMPLE | Nasal epithelial cells |
TECHNIQUES | Microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
GEO_PRIDE_ACCESS_NO | GSE44037 |
REFERENCE | 24282527 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-AHI1 for Mouse |
Record No:162
ACCESS NO | 102049 |
GENE | ARMCX1 |
DESCRIPTION | Armadillo repeat containing X-linked 1 |
NCBI ENTREZ ACCESS NO | 51309 |
UNIPROT ACCESS NO | Q9P291 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis and asthma |
SAMPLE | Nasal epithelial cells |
TECHNIQUES | Microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
GEO_PRIDE_ACCESS_NO | GSE44037 |
REFERENCE | 24282527 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-ARMCX1 for Mouse/Rat/Human |
Record No:163
ACCESS NO | 102079 |
GENE | ALOX5 |
DESCRIPTION | Arachidonate 5-lipoxygenase |
NCBI ENTREZ ACCESS NO | 240 |
UNIPROT ACCESS NO | P09917 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic asthma |
SAMPLE | CD4+ T cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Differentially expressed in asthma. Involved in leukotriene and prostaglandin signalling. |
GEO_PRIDE_ACCESS_NO | GSE14908 |
REFERENCE | 19414752 |
DRUG TARGET | BE0000248 |
MONCLONAL ANTIBODY | Anti-5 Lipoxygenase for Mouse/Rat/Human |
Record No:164
ACCESS NO | 102088 |
GENE | ARRDC2 |
DESCRIPTION | Arrestin domain containing 2 |
NCBI ENTREZ ACCESS NO | 27106 |
UNIPROT ACCESS NO | Q8TBH0 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic asthma |
SAMPLE | CD4+ T cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Differentially expressed in asthma. Involved in signal transduction. |
GEO_PRIDE_ACCESS_NO | GSE14908 |
REFERENCE | 19414752 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:165
ACCESS NO | 102101 |
GENE | APBB1IP |
DESCRIPTION | Rap1-interacting adaptor molecule |
NCBI ENTREZ ACCESS NO | 54518 |
UNIPROT ACCESS NO | Q7Z5R6 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic asthma |
SAMPLE | CD4+ T cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Differentially expressed in asthma. Involved in TCR signalling. |
GEO_PRIDE_ACCESS_NO | GSE14908 |
REFERENCE | 19414752 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:166
ACCESS NO | 102137 |
GENE | ALOX15 |
DESCRIPTION | Arachidonate 15-lipoxygenase |
NCBI ENTREZ ACCESS NO | 246 |
UNIPROT ACCESS NO | P16050 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic asthma |
SAMPLE | Bronchial Biopsy |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | GSE41649 |
REFERENCE | 19842841 |
DRUG TARGET | BE0000309 |
MONCLONAL ANTIBODY | Anti-15 Lipoxygenase 1 for Rat/Dog/Monkey |