BROWSE RESULT OF B

32 Records

 

Record No:1


ACCESS NO100030
GENEBTG2
DESCRIPTIONBTG family-member 2
NCBI ENTREZ ACCESS NO7832
UNIPROT ACCESS NOP78543
ORGANISMHuman
DISEASE PHENOTYPEAsthma ( comparison between high and low socio-economic conditions [SEC])
SAMPLECD2+ cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene is upregulated more in high SEC group. It is related to cell cycle control and helps correcting the effects of DNA damage.
GEO_PRIDE_ACCESS_NOGSE7894
REFERENCE19001005
DRUG TARGET
MONCLONAL ANTIBODYAnti-BTG2 for Human


Record No:2


ACCESS NO100170
GENEBIRC3
DESCRIPTIONBaculoviral IAP repeat-containing 3
NCBI ENTREZ ACCESS NO330
UNIPROT ACCESS NOQ13489
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is a cell communication protein significantly upregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYAnti-cIAP2 for Human


Record No:3


ACCESS NO100350
GENEBCL3
DESCRIPTIONB cell CLL/lymphoma 3
NCBI ENTREZ ACCESS NO602
UNIPROT ACCESS NOP20749
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESIllumina Human Ref8 BeadChip arrays
OMICSGenomics
STUDY High Throughput
COMMENTSIt is upregulated in asthma exacerbation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19187333
DRUG TARGET
MONCLONAL ANTIBODYAnti-Bcl3 for Human


Record No:4


ACCESS NO100362
GENEB2m
DESCRIPTIONbeta-2 microglobulin
NCBI ENTREZ ACCESS NO24223
UNIPROT ACCESS NOP07151
ORGANISMRat
DISEASE PHENOTYPEEarly airway response (EAR) phase of asthma
SAMPLELung tissue
TECHNIQUESSerial analysis of gene expression (SAGE)
OMICSGenomics
STUDY High Throughput
COMMENTSIt participates in antigen processing and presentation
GEO_PRIDE_ACCESS_NON/A
REFERENCE18922145
DRUG TARGETBE0003777
MONCLONAL ANTIBODYAnti-beta 2 Microglobulin for Human


Record No:5


ACCESS NO100373
GENEBlvrb
DESCRIPTIONBiliverdin reductase B
NCBI ENTREZ ACCESS NO233016
UNIPROT ACCESS NOQ923D2
ORGANISMMouse
DISEASE PHENOTYPEOccupational asthma induced by chemicals
SAMPLEAuricular lymph nodes
TECHNIQUES2D DIGE and MALDI-TOF-MS
OMICSProteomics
STUDY High Throughput
COMMENTSIt is upregulated in asthma inflammation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23038679
DRUG TARGETBE0000595
MONCLONAL ANTIBODYAnti-BLVRB for Human


Record No:6


ACCESS NO100440
GENEBPI
DESCRIPTIONBactericidal/permeability-increasing protein
NCBI ENTREZ ACCESS NO671
UNIPROT ACCESS NOP17213
ORGANISMHuman
DISEASE PHENOTYPESevere asthma
SAMPLECD4 + T cells
TECHNIQUESMicroarray and Real time Q-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is upregulated in asthma inflammation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21917308
DRUG TARGETBE0001112
MONCLONAL ANTIBODYAnti-BPIFB1 for Mouse/Human


Record No:7


ACCESS NO100451
GENEBPI
DESCRIPTIONBactericidal/permeability-increasing protein
NCBI ENTREZ ACCESS NO671
UNIPROT ACCESS NOP17213
ORGANISMHuman
DISEASE PHENOTYPESevere asthma
SAMPLECD8 + T cells
TECHNIQUESMicroarray and Real time Q-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is upregulated in asthma inflammation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21917308
DRUG TARGETBE0001112
MONCLONAL ANTIBODYAnti-BPIFB1 for Mouse/Human


Record No:8


ACCESS NO100472
GENEBACH1
DESCRIPTIONBTB and CNC homology 1 basic leucine zipper transcription factor 1
NCBI ENTREZ ACCESS NO571
UNIPROT ACCESS NOO14867
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEAirway smooth muscle cell (ASM) line
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt had diminished responses to dexamethasone treatment in asthmatic cell line A-HASM1.
GEO_PRIDE_ACCESS_NOGSE3946
REFERENCE21257922
DRUG TARGET
MONCLONAL ANTIBODYAnti-BACH1.3 for Human


Record No:9


ACCESS NO100480
GENEBLMH
DESCRIPTIONBleomycin hydrolase
NCBI ENTREZ ACCESS NO642
UNIPROT ACCESS NOQ13867
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis and eczema
SAMPLESkin tapings
TECHNIQUESnano-HPLC-MS/MS (ion trap)
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein exhibited a lower expression (although not significant) in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. It is thought to degrade the filaggrin protein into its constitutent amino acids and these amino acids are the basic components of skin natural moisturizing factor.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21211653
DRUG TARGET
MONCLONAL ANTIBODYAnti-BLMH for Mouse/Rat/Human


Record No:10


ACCESS NO100596
GENEBPIFA1
DESCRIPTIONLPLUNC1 protein
NCBI ENTREZ ACCESS NO51297
UNIPROT ACCESS NOQ9NP55
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEBroncho Alveolar Lavage (BAL)F
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSHost defense proteins involved in innate immunity against pathogens
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-PLUNC for Mouse/Rat/Human


Record No:11


ACCESS NO100753
GENEBax
DESCRIPTIONApoptosis regulator
NCBI ENTREZ ACCESS NO12028
UNIPROT ACCESS NOQ07813
ORGANISMbalb C mice
DISEASE PHENOTYPEAllergic asthma after challenge with Aspergillus fumigatus
SAMPLEPeriferal blood monocytes
TECHNIQUESMicroarray (agilent)
OMICSGenomics
STUDY High Throughput
COMMENTSInvolved in inflammatory response.Upregulated in fungal allergen challenge.Selected based on fold change.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20840155
DRUG TARGETBE0003420
MONCLONAL ANTIBODYAnti-Bax for Mouse/Rat/Human


Record No:12


ACCESS NO100790
GENEBex
DESCRIPTIONProtein BEX2
NCBI ENTREZ ACCESS NO12069
UNIPROT ACCESS NOQ9WTZ8
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAcute and chronic asthma
SAMPLELung Tissue
TECHNIQUESGeneChip Expression 3 (affymetrix) microarray
OMICSGenomics
STUDY High Throughput
COMMENTSDownregulated in mouse model of asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19028979
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:13


ACCESS NO100823
GENEB2m
DESCRIPTIONBeta-2 microglobulin
NCBI ENTREZ ACCESS NO12010
UNIPROT ACCESS NOP01887
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAcute and chronic asthma
SAMPLELung Tissue
TECHNIQUESGeneChip Expression 3 (affymetrix) microarray
OMICSGenomics
STUDY High Throughput
COMMENTSComponent of major histocompatibility complex. Responsible for antigen presentation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19028979
DRUG TARGETBE0003777
MONCLONAL ANTIBODYAnti-beta 2 Microglobulin for Human


Record No:14


ACCESS NO100824
GENEBirc5
DESCRIPTIONBaculoviral IAP repeat containing 5
NCBI ENTREZ ACCESS NO11799
UNIPROT ACCESS NOO70201
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAcute and chronic asthma
SAMPLELung Tissue
TECHNIQUESGeneChip Expression 3 (affymetrix) microarray
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTS Upregulated in short exposure and downregulated in long exposure.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19028979
DRUG TARGETBE0003408
MONCLONAL ANTIBODYAnti-Survivin for Human


Record No:15


ACCESS NO100999
GENEBIRC3
DESCRIPTIONBaculoviral IAP repeat containing 3
NCBI ENTREZ ACCESS NO330
UNIPROT ACCESS NOQ13489
ORGANISMHuman
DISEASE PHENOTYPEAsthma with eosinophilic and neutrophilic inflammation
SAMPLESputum
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt shows highest expression in patients with eosinophilic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24582314
DRUG TARGETBE0000949
MONCLONAL ANTIBODYAnti-cIAP2 for Human


Record No:16


ACCESS NO101000
GENEBPIFB1
DESCRIPTIONBPI fold containing family B - member 1
NCBI ENTREZ ACCESS NO92747
UNIPROT ACCESS NOQ8TDL5
ORGANISMHuman
DISEASE PHENOTYPEAsthma with eosinophilic and neutrophilic inflammation
SAMPLESputum
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt shows highest expression in patients with eosinophilic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24582314
DRUG TARGET
MONCLONAL ANTIBODYAnti-BPIFB1 for Mouse/Human


Record No:17


ACCESS NO101030
GENEBPIFA1
DESCRIPTIONBPI fold-containing family A member 1
NCBI ENTREZ ACCESS NO51297
UNIPROT ACCESS NOQ9NP55
ORGANISMHuman
DISEASE PHENOTYPEAtopic eczema (AE)
SAMPLEVernix
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is strongly upregulated in atopic eczema.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24205894
DRUG TARGET
MONCLONAL ANTIBODYAnti-Plunc for Mouse/Rat/Human


Record No:18


ACCESS NO101032
GENEBPIFB1
DESCRIPTIONBPI fold-containing family B member 1
NCBI ENTREZ ACCESS NO92747
UNIPROT ACCESS NOQ8TDL5
ORGANISMHuman
DISEASE PHENOTYPEAtopic eczema (AE)
SAMPLEVernix
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is strongly upregulated in atopic eczema.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24205894
DRUG TARGET
MONCLONAL ANTIBODYAnti-BPIFB1 for Mouse/Human


Record No:19


ACCESS NO101243
GENEBDNF
DESCRIPTIONBrain Derived Neurotrophic Factor
NCBI ENTREZ ACCESS NO627
UNIPROT ACCESS NOP23560
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLEgenomic DNA
TECHNIQUESSNP typing
OMICSGenomics
STUDY Low Throughput
COMMENTSThe SNP rs10767664 is strongly linked (r2 = 0.95) to the functional polymorphism rs6265 (Val66Met) and this has previously been reported to be associated to allergic phenotypes and also shown to affect BDNF expression. BDNF is a therefore a key molecular player in allergy. Further studies on polymorphisms within BDNF may shed light on its role in the pathogenesis of allergic diseases and potentially serve as biomarkers for allergic disease.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21723144
DRUG TARGETBE0003605
MONCLONAL ANTIBODYAnti-BDNF for Mouse/Rat/Human


Record No:20


ACCESS NO101432
GENEBatf3
DESCRIPTIONBasic leucine zipper transcription factor ATF-like 3
NCBI ENTREZ ACCESS NO381319
UNIPROT ACCESS NOQ9D275
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSOverexpressed after 3hours and 12 hours of allergenic mould extract challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:21


ACCESS NO101494
GENEBhlhb8
DESCRIPTIONBasic helix-loop-helix family member a15
NCBI ENTREZ ACCESS NO17341
UNIPROT ACCESS NOQ9QYC3
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3 and 12 hours of allergen induction in asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:22


ACCESS NO101756
GENEBPIFB1
DESCRIPTIONC20orf114 (LPLUNC1 protein)
NCBI ENTREZ ACCESS NO92747
UNIPROT ACCESS NOA2A2R0
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis local matrix protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-BPIFB1 [4H2] for Mouse/Human


Record No:23


ACCESS NO101766
GENEBPIFA1
DESCRIPTIONPalate lung and nasal epithelium clone protein
NCBI ENTREZ ACCESS NO51297
UNIPROT ACCESS NOQ9NP55
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis local matrix protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-Plunc [EPR8381] for Mouse/Rat/human


Record No:24


ACCESS NO101937
GENEBGN
DESCRIPTIONBiglycan precursor
NCBI ENTREZ ACCESS NO633
UNIPROT ACCESS NOP21810
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPeripheral blood eosinophils
TECHNIQUES2DE-PAGE and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic dermatitis patients eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15832365
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:25


ACCESS NO101947
GENEBCL3
DESCRIPTIONB cell CLL/lymphoma 3
NCBI ENTREZ ACCESS NO602
UNIPROT ACCESS NOP20749
ORGANISMHuman(Asthmatic children)
DISEASE PHENOTYPEAsthma( Mite sensitized asthma)
SAMPLEPeripheral Blood Mononuclear Cells
TECHNIQUESMicroarray and RT-PCR
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19187333
DRUG TARGET
MONCLONAL ANTIBODYAnti-Bcl3 for Human


Record No:26


ACCESS NO101993
GENEBBS1
DESCRIPTIONBardet-Biedl syndrome 1
NCBI ENTREZ ACCESS NO582
UNIPROT ACCESS NOQ8NFJ9
ORGANISMHuman
DISEASE PHENOTYPEAsthma and allergic rhinitis
SAMPLEEpithelial cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDownregulated in patients with allergic rhinitis in upper airways.
GEO_PRIDE_ACCESS_NOGSE51392
REFERENCE24475887
DRUG TARGET
MONCLONAL ANTIBODYAnti-BBS1 for Mouse/Rat/Human


Record No:27


ACCESS NO102009
GENEBMP6
DESCRIPTIONBone morphogenetic protein 6
NCBI ENTREZ ACCESS NO654
UNIPROT ACCESS NOP22004
ORGANISMHuman
DISEASE PHENOTYPEAsthma and allergic rhinitis
SAMPLEEpithelial cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in the lower airways in patients with allergic rhinitis.
GEO_PRIDE_ACCESS_NOGSE51392
REFERENCE24475887
DRUG TARGET
MONCLONAL ANTIBODYAnti-BMP6 for Mouse/Rat/Human


Record No:28


ACCESS NO102024
GENEBST2
DESCRIPTIONBone marrow stromal cell antigen 2
NCBI ENTREZ ACCESS NO684
UNIPROT ACCESS NOQ10589
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis and asthma
SAMPLEBronchial epithelial cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput
COMMENTSHighly expressed in patients with allergic rhinitis and asthma.(Data in supplimentary table).
GEO_PRIDE_ACCESS_NOGSE44037
REFERENCE24282527
DRUG TARGET
MONCLONAL ANTIBODYAnti-BST2 for Human


Record No:29


ACCESS NO102069
GENEBCL2
DESCRIPTIONB cell CLL/lymphoma 2
NCBI ENTREZ ACCESS NO596
UNIPROT ACCESS NOP10415
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDifferentially expressed in asthma. Involved in apoptosis.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGETBE0000246
MONCLONAL ANTIBODYN/A


Record No:30


ACCESS NO102070
GENEBTG1
DESCRIPTIONB cell translocation gene 1
NCBI ENTREZ ACCESS NO694
UNIPROT ACCESS NOP62324
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSDifferentially expressed in asthma. Involved in apoptosis.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYAnti-BTG1 for Mouse/Rat/Human


Record No:31


ACCESS NO102121
GENEBATF
DESCRIPTIONBasic leucine zipper transcription factor ATF-like
NCBI ENTREZ ACCESS NO10538
UNIPROT ACCESS NOQ16520
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in atopic asthma. Involved in Transcriptional regulation.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYAnti-BATF for Human


Record No:32


ACCESS NO102127
GENEBCL9L
DESCRIPTIONBcell CLL/lymphoma 9-like
NCBI ENTREZ ACCESS NO283149
UNIPROT ACCESS NOQ86UU0
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDifferentialy expressed in asthma. Involved in beta catenin/wnt signalling pathway.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYN/A