BROWSE RESULT OF C
| 439 Records |
| ACCESS NO | 100008 |
| GENE | CD14 |
| DESCRIPTION | CD14 molecule |
| NCBI ENTREZ ACCESS NO | 929 |
| UNIPROT ACCESS NO | P08571 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in low SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | BE0002442 |
| MONCLONAL ANTIBODY | N/A |
Record No:2
| ACCESS NO | 100024 |
| GENE | CD37 |
| DESCRIPTION | CD37 molecule |
| NCBI ENTREZ ACCESS NO | 951 |
| UNIPROT ACCESS NO | P11049 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in low SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD37 for Mouse/Human |
Record No:3
| ACCESS NO | 100057 |
| GENE | CCR2 |
| DESCRIPTION | Chemokine (C-C motif) receptor 2 |
| NCBI ENTREZ ACCESS NO | 729230 |
| UNIPROT ACCESS NO | P41597 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in leukocyte migration. This exacerbation-associated gene is upregulated by Th2 cytokines. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CCR2 [E68] for Rat/Human/Monkey |
Record No:4
| ACCESS NO | 100058 |
| GENE | CCR1 |
| DESCRIPTION | Chemokine (C-C motif) receptor 1 |
| NCBI ENTREZ ACCESS NO | 1230 |
| UNIPROT ACCESS NO | P32246 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in leukocyte migration |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CCR1 for Human |
Record No:5
| ACCESS NO | 100059 |
| GENE | CXCR2 (IL8RB) |
| DESCRIPTION | Chemokine (C-X-C motif) receptor 2 |
| NCBI ENTREZ ACCESS NO | 3579 |
| UNIPROT ACCESS NO | P25025 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in leukocyte migration |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CXCR2 for Human |
Record No:6
| ACCESS NO | 100060 |
| GENE | CXCL5 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 5 |
| NCBI ENTREZ ACCESS NO | 6374 |
| UNIPROT ACCESS NO | P42830 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in leukocyte migration |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CXCL5 for Human |
Record No:7
| ACCESS NO | 100061 |
| GENE | CXCL1 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 1 |
| NCBI ENTREZ ACCESS NO | 2919 |
| UNIPROT ACCESS NO | P09341 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in leukocyte migration |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:8
| ACCESS NO | 100067 |
| GENE | CD14 |
| DESCRIPTION | CD14 molecule |
| NCBI ENTREZ ACCESS NO | 929 |
| UNIPROT ACCESS NO | P08571 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in innate immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:9
| ACCESS NO | 100072 |
| GENE | CLEC4D |
| DESCRIPTION | C-type lectin domain family 4 member D |
| NCBI ENTREZ ACCESS NO | 338339 |
| UNIPROT ACCESS NO | Q8WXI8 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in innate immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:10
| ACCESS NO | 100074 |
| GENE | CASP1 |
| DESCRIPTION | Caspase 1 |
| NCBI ENTREZ ACCESS NO | 834 |
| UNIPROT ACCESS NO | P29466 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in innate immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | BE0000444 |
| MONCLONAL ANTIBODY | Anti-Caspase-1 for Human |
Record No:11
| ACCESS NO | 100091 |
| GENE | C3AR1 |
| DESCRIPTION | Complement component 3a receptor 1 |
| NCBI ENTREZ ACCESS NO | 719 |
| UNIPROT ACCESS NO | Q16581 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in complement and coagulation cascade. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-C3a Receptor for Human |
Record No:12
| ACCESS NO | 100095 |
| GENE | CALD1 |
| DESCRIPTION | Caldesmon 1 |
| NCBI ENTREZ ACCESS NO | 800 |
| UNIPROT ACCESS NO | Q05682 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene is associated with inflammation. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Caldesmon for Mouse/Rat/Human |
Record No:13
| ACCESS NO | 100100 |
| GENE | Clca3 |
| DESCRIPTION | Chloride channel calcium activated 3 |
| NCBI ENTREZ ACCESS NO | 23844 |
| UNIPROT ACCESS NO | Q9D7Z6 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is an asthma signature gene highly induced by allergens but is not affected by the treatment of IL-4 and/or IL-13. However it belongs to the IL-13 induced inflammatory pathway as its expression is diminished in IL-13 knock out mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:14
| ACCESS NO | 100101 |
| GENE | Ccl8 |
| DESCRIPTION | Chemokine (C-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 20307 |
| UNIPROT ACCESS NO | Q9Z121 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is an asthma signature gene highly induced by allergens. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | BE0002941 |
| MONCLONAL ANTIBODY | N/A |
Record No:15
| ACCESS NO | 100102 |
| GENE | Ccl9 |
| DESCRIPTION | Chemokine (C-C motif) ligand 9 |
| NCBI ENTREZ ACCESS NO | 20308 |
| UNIPROT ACCESS NO | P51670 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This chemokine is an asthma signature gene highly induced by allergens. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:16
| ACCESS NO | 100103 |
| GENE | Ccl11 |
| DESCRIPTION | Small chemokine (C-C motif) ligand 11 or Eotaxin |
| NCBI ENTREZ ACCESS NO | 20292 |
| UNIPROT ACCESS NO | P48298 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an eosinophil-specific chemokine induced by IL-13 and not by IL-4. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | BE0003389 |
| MONCLONAL ANTIBODY | Anti-Eotaxin for Human |
Record No:17
| ACCESS NO | 100104 |
| GENE | C1qa |
| DESCRIPTION | Complement component 1 - q subcomponent - alpha polypeptide |
| NCBI ENTREZ ACCESS NO | 12259 |
| UNIPROT ACCESS NO | P98086 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an IL-4 specific component of complement pathway involved in immune regulation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | BE0002094 |
| MONCLONAL ANTIBODY | Anti-C1QA for Human |
Record No:18
| ACCESS NO | 100105 |
| GENE | C1qc (C1qg) |
| DESCRIPTION | Complement component 1 - q subcomponent - gamma polypeptide |
| NCBI ENTREZ ACCESS NO | 12262 |
| UNIPROT ACCESS NO | Q02105 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an IL-4 specific component of complement pathway involved in immune regulation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | BE0002096 |
| MONCLONAL ANTIBODY | Anti-C1QC for Human |
Record No:19
| ACCESS NO | 100106 |
| GENE | Chi3l3 |
| DESCRIPTION | Chitinase 3 like 3 |
| NCBI ENTREZ ACCESS NO | 12655 |
| UNIPROT ACCESS NO | O35744 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This inflammatory gene is commonly induced by allergens and Th2 cytokines such as IL-4 and IL-13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:20
| ACCESS NO | 100107 |
| GENE | Chia1 (Chia) |
| DESCRIPTION | Chitinase - acidic |
| NCBI ENTREZ ACCESS NO | 81600 |
| UNIPROT ACCESS NO | Q91XA9 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This inflammatory gene is commonly induced by allergens and Th2 cytokines such as IL-4 and IL-13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:21
| ACCESS NO | 100115 |
| GENE | Ccl7 |
| DESCRIPTION | Chemokine (C-C motif) ligand 7 |
| NCBI ENTREZ ACCESS NO | 20306 |
| UNIPROT ACCESS NO | Q03366 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This chemokine is an asthma signature gene highly induced by Th2 cytokines such as IL-4 and IL-13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | BE0002941 |
| MONCLONAL ANTIBODY | N/A |
Record No:22
| ACCESS NO | 100122 |
| GENE | Ctsk |
| DESCRIPTION | Cathepsin K |
| NCBI ENTREZ ACCESS NO | 13038 |
| UNIPROT ACCESS NO | P55097 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This matrix homeostatic gene is specifically induced by Th2 cytokines such as IL-4 and IL-13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | BE0003417 |
| MONCLONAL ANTIBODY | Anti-Cathepsin K for Human |
Record No:23
| ACCESS NO | 100126 |
| GENE | Ccr5 |
| DESCRIPTION | Chemokine (C-C motif) receptor 5 |
| NCBI ENTREZ ACCESS NO | 12774 |
| UNIPROT ACCESS NO | P51682 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an IL-4 specific chemokine gene induced in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | BE0000911 |
| MONCLONAL ANTIBODY | Anti-CCR5 for Mouse/Rat/Human |
Record No:24
| ACCESS NO | 100127 |
| GENE | Cd83 |
| DESCRIPTION | CD83 antigen |
| NCBI ENTREZ ACCESS NO | 12522 |
| UNIPROT ACCESS NO | O88324 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is induced by combined rIL-4/rIL-13 treatment and by House dust mite but not by Ragweed pollen allergen. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD83 for Mouse/Rat/Human |
Record No:25
| ACCESS NO | 100135 |
| GENE | Cfp |
| DESCRIPTION | Complement factor properdin |
| NCBI ENTREZ ACCESS NO | 18636 |
| UNIPROT ACCESS NO | P11680 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an IL-4 specific complement component induced in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:26
| ACCESS NO | 100136 |
| GENE | Ch25h |
| DESCRIPTION | Cholesterol 25-hydroxylase |
| NCBI ENTREZ ACCESS NO | 12642 |
| UNIPROT ACCESS NO | Q9Z0F5 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an IL-4 specific lipid metabolism gene induced in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CH25H for Rat/Human |
Record No:27
| ACCESS NO | 100143 |
| GENE | CCL20 |
| DESCRIPTION | MIP-3 |
| NCBI ENTREZ ACCESS NO | 6364 |
| UNIPROT ACCESS NO | P78556 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 3 alpha for Human |
Record No:28
| ACCESS NO | 100145 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Interleukin 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:29
| ACCESS NO | 100146 |
| GENE | CXCL3 |
| DESCRIPTION | GRO- 3 |
| NCBI ENTREZ ACCESS NO | 2921 |
| UNIPROT ACCESS NO | P19876 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:30
| ACCESS NO | 100147 |
| GENE | CXCL2 |
| DESCRIPTION | GRO beta |
| NCBI ENTREZ ACCESS NO | 2920 |
| UNIPROT ACCESS NO | P19875 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:31
| ACCESS NO | 100155 |
| GENE | CXCL1 |
| DESCRIPTION | GRO - 1 |
| NCBI ENTREZ ACCESS NO | 2919 |
| UNIPROT ACCESS NO | P09341 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:32
| ACCESS NO | 100164 |
| GENE | COL8A1 |
| DESCRIPTION | Collagen VIII alpha 1 |
| NCBI ENTREZ ACCESS NO | 1295 |
| UNIPROT ACCESS NO | P27658 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:33
| ACCESS NO | 100173 |
| GENE | CHRNB1 |
| DESCRIPTION | Cholinergic receptor nicotinic beta polypeptide-1 |
| NCBI ENTREZ ACCESS NO | 1140 |
| UNIPROT ACCESS NO | P11230 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | BE0004662 |
| MONCLONAL ANTIBODY | Anti-Nicotinic Acetylcholine Receptor beta for Mouse/Rat/Human |
Record No:34
| ACCESS NO | 100175 |
| GENE | CRABP2 |
| DESCRIPTION | Cellular retinoic acid binding protein 2 |
| NCBI ENTREZ ACCESS NO | 1382 |
| UNIPROT ACCESS NO | P29373 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | BE0000782 |
| MONCLONAL ANTIBODY | Anti-CRABP2 [EPR14256(B)] for Human |
Record No:35
| ACCESS NO | 100178 |
| GENE | COL5A1 |
| DESCRIPTION | Collagen V alpha 1 |
| NCBI ENTREZ ACCESS NO | 1289 |
| UNIPROT ACCESS NO | P20908 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This is a cell communication protein significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Collagen Type V for Human |
Record No:36
| ACCESS NO | 100183 |
| GENE | C1QTNF1 |
| DESCRIPTION | C1q and tumour necrosis factor related protein 1 |
| NCBI ENTREZ ACCESS NO | 114897 |
| UNIPROT ACCESS NO | Q9BXJ1 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a immunity and defense related protein significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:37
| ACCESS NO | 100193 |
| GENE | CDKN1C |
| DESCRIPTION | Cyclin-dependent kinase inhibitor 1C |
| NCBI ENTREZ ACCESS NO | 1028 |
| UNIPROT ACCESS NO | P49918 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an enzyme inhibitory protein significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-p57 Kip2 for Mouse/Rat/Human |
Record No:38
| ACCESS NO | 100206 |
| GENE | CYP26B1 |
| DESCRIPTION | Cytochrome P450 family 26 - subfamily B polypeptide 1 |
| NCBI ENTREZ ACCESS NO | 56603 |
| UNIPROT ACCESS NO | Q9NR63 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene codes for a metabolic enzyme significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Cytochrome P450 26B [EPR13182] for Mouse/Rat/Human |
Record No:39
| ACCESS NO | 100215 |
| GENE | CHAC1 |
| DESCRIPTION | Cation transport regulator-like 1 |
| NCBI ENTREZ ACCESS NO | 79094 |
| UNIPROT ACCESS NO | Q9BUX1 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene codes for a transporter significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CHAC1 [1G2] for Human |
Record No:40
| ACCESS NO | 100220 |
| GENE | CACNG4 |
| DESCRIPTION | Calcium channel voltage - dependent gamma subunit 4 |
| NCBI ENTREZ ACCESS NO | 27092 |
| UNIPROT ACCESS NO | Q9UBN1 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene codes for a calcium binding protein significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:41
| ACCESS NO | 100243 |
| GENE | CXCL3 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 3 |
| NCBI ENTREZ ACCESS NO | 2921 |
| UNIPROT ACCESS NO | P19876 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is a chemokine acting neutrophil chemoattractants. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:42
| ACCESS NO | 100244 |
| GENE | CXCL2 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 2 |
| NCBI ENTREZ ACCESS NO | 2920 |
| UNIPROT ACCESS NO | P19875 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is a chemokine acting as neutrophil chemoattractants. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:43
| ACCESS NO | 100246 |
| GENE | CSF3 |
| DESCRIPTION | Colony stimulating factor 3 (granulocyte) |
| NCBI ENTREZ ACCESS NO | 1440 |
| UNIPROT ACCESS NO | P09919 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is a chemokine involved in eosinophil development. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-G-CSF for Human |
Record No:44
| ACCESS NO | 100248 |
| GENE | CXCL1 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 1 |
| NCBI ENTREZ ACCESS NO | 2919 |
| UNIPROT ACCESS NO | P09341 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is responsible for corticosteroid resistance in asthma. It also acts as a chemoattractent of immune cells. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:45
| ACCESS NO | 100252 |
| GENE | CCL20 |
| DESCRIPTION | Chemokine (C-C motif) ligand 20 |
| NCBI ENTREZ ACCESS NO | 6364 |
| UNIPROT ACCESS NO | P78556 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulation of this chemokline takes place in rhinovirus induced allergic asthma. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 3 alpha for Human |
Record No:46
| ACCESS NO | 100254 |
| GENE | CSF2 |
| DESCRIPTION | Colony stimulating factor 2 (granulocytemacrophage) |
| NCBI ENTREZ ACCESS NO | 1437 |
| UNIPROT ACCESS NO | P04141 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is a cytokine upregulated in rhinovirus induced allergic asthma. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | BE0002481 |
| MONCLONAL ANTIBODY | Anti-GM-CSF for Mouse/Human |
Record No:47
| ACCESS NO | 100266 |
| GENE | CDKN2B |
| DESCRIPTION | cyclin-dependent kinase inhibitor 2B (p15 inhibits CDK4) |
| NCBI ENTREZ ACCESS NO | 1030 |
| UNIPROT ACCESS NO | P42772 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell cycle regulatory protein down regulated after rhinoviral infection. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-p15 INK4b for Human |
Record No:48
| ACCESS NO | 100279 |
| GENE | CD200 |
| DESCRIPTION | CD200 antigen |
| NCBI ENTREZ ACCESS NO | 4345 |
| UNIPROT ACCESS NO | P41217 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays and real time |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is type 1a transmembrane protein expressed by thymocytes and activated immune cells (T cells and B cells). In this study it was observed that CD200 expression was significantly reduced during asthma exacerbation and that this reduction was not due to infection. CD200/CD200R interactions transmit inhibitory signals to cells of the haematopoetic lineage and these interactions are reported to play various roles in immune responses such as the induction of regulatory T cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD200 / OX2 for Human |
Record No:49
| ACCESS NO | 100289 |
| GENE | Clec4a2 |
| DESCRIPTION | C-type lectin domain family 4 member A-CLEC4A |
| NCBI ENTREZ ACCESS NO | 26888 |
| UNIPROT ACCESS NO | Q9QZ15 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in cell adhesion and it was found to be downregulated. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CLECSF for Human |
Record No:50
| ACCESS NO | 100295 |
| GENE | Cd63 |
| DESCRIPTION | CD63 antigen(LAMP-3 or granulophysin) |
| NCBI ENTREZ ACCESS NO | 12512 |
| UNIPROT ACCESS NO | P41731 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in immune cell trafficking and antigen presentation and inflammatory response. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD63 for Human |
Record No:51
| ACCESS NO | 100296 |
| GENE | Cd83 |
| DESCRIPTION | CD83 antigen (HB15) |
| NCBI ENTREZ ACCESS NO | 12522 |
| UNIPROT ACCESS NO | O88324 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in cell mediated immune response and inflammatory response and also in antigen presentation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD83 for Human |
Record No:52
| ACCESS NO | 100297 |
| GENE | Ccl4 |
| DESCRIPTION | Macrophage inflammatory protein 1-BETA |
| NCBI ENTREZ ACCESS NO | 20303 |
| UNIPROT ACCESS NO | P14097 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in cell mediated immune cell trafficking and inflammatory response and also in antigen presentation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CCL4L2 for Human |
Record No:53
| ACCESS NO | 100298 |
| GENE | Ccl3 |
| DESCRIPTION | Â Macrophage inflammatory protein 1-ALPHA |
| NCBI ENTREZ ACCESS NO | 20302 |
| UNIPROT ACCESS NO | P10855 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It has been found to be induced in monocyte cells upon allergenic fungal exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | BE0002471 |
| MONCLONAL ANTIBODY | N/A |
Record No:54
| ACCESS NO | 100308 |
| GENE | Col4a1 |
| DESCRIPTION | Procollagen type IV a -1 |
| NCBI ENTREZ ACCESS NO | 290905 |
| UNIPROT ACCESS NO | F1MA59 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in ECM receptor interaction and cell communication. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Collagen IV for Human |
Record No:55
| ACCESS NO | 100309 |
| GENE | Ccnd1 |
| DESCRIPTION | Cyclin d1 |
| NCBI ENTREZ ACCESS NO | 58919 |
| UNIPROT ACCESS NO | P39948 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in focal adhesion and WNT signalling pathway. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | BE0001027 |
| MONCLONAL ANTIBODY | Anti-Cyclin D1 [CD1.1] for Mouse/Rat/Human |
Record No:56
| ACCESS NO | 100314 |
| GENE | Cav1 |
| DESCRIPTION | Caveolin |
| NCBI ENTREZ ACCESS NO | 25404 |
| UNIPROT ACCESS NO | Q3MHT6 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | When the MaxiK channel was activated by Ca2+ spikes or an increase in cAMP then it forms complexes with the caveolin. These mixed signals resulted in cascade-like activation of the MAPK and focal adhesion pathways. It plays a crucial role in processing and integrating extracellular signals leading to airway inflammation and remodelling. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CaV1.3 for Mouse/Rat/Human |
Record No:57
| ACCESS NO | 100316 |
| GENE | Col6a2 |
| DESCRIPTION | Procollagen type VI a -2 |
| NCBI ENTREZ ACCESS NO | 361821 |
| UNIPROT ACCESS NO | F1LNH3 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) and qRT- |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene is downregulated with expression being decreased over 10-fold. These changes in gene expression may affect the immune response or other biological processes relevant to asthma. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Collagen VI alpha 2 [EPR7889(N)] for Mouse/Human |
Record No:58
| ACCESS NO | 100324 |
| GENE | Cldn18 |
| DESCRIPTION | Similar to claudin-18a1.2 |
| NCBI ENTREZ ACCESS NO | 315953 |
| UNIPROT ACCESS NO | Q5I0E5 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in leucocyte transendothelial migration and tight junction. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:59
| ACCESS NO | 100334 |
| GENE | Cfb |
| DESCRIPTION | Complement factor B |
| NCBI ENTREZ ACCESS NO | 14962 |
| UNIPROT ACCESS NO | P04186 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced chemicals |
| SAMPLE | Broncho Alveolar Lavage (BAL) |
| TECHNIQUES | 2D DIGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is indispensable in eliciting airway hyperresponsiveness and airway inflammation in mice sensitized and challenged with allergen. It contributes to airway hyperresponsiveness and inflammation in chemically induced asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20860378 |
| DRUG TARGET | BE0001701 |
| MONCLONAL ANTIBODY | N/A |
Record No:60
| ACCESS NO | 100340 |
| GENE | Calr |
| DESCRIPTION | Calreticulin |
| NCBI ENTREZ ACCESS NO | 12317 |
| UNIPROT ACCESS NO | P14211 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced chemicals |
| SAMPLE | Auricular Lymph Nodes |
| TECHNIQUES | 2D DIGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in neutrophil chemotaxis. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20860378 |
| DRUG TARGET | BE0002109 |
| MONCLONAL ANTIBODY | N/A |
Record No:61
| ACCESS NO | 100343 |
| GENE | CAST |
| DESCRIPTION | Calpastatin |
| NCBI ENTREZ ACCESS NO | 831 |
| UNIPROT ACCESS NO | P20810 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is upregulated in asthma exacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | BE0000904 |
| MONCLONAL ANTIBODY | Anti-Calpastatin [2G11D6] FOR Human/Rat/Rabbit |
Record No:62
| ACCESS NO | 100344 |
| GENE | CREB5 |
| DESCRIPTION | cAMP responsive element binding protein 5 |
| NCBI ENTREZ ACCESS NO | 9586 |
| UNIPROT ACCESS NO | Q02930 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is upregulated in asthma exacerbation and upper respiratory tract infection. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CREB5 for Mouse/Rat/Human |
Record No:63
| ACCESS NO | 100345 |
| GENE | CSDE1 |
| DESCRIPTION | Cold shock domain containing E1 |
| NCBI ENTREZ ACCESS NO | 7812 |
| UNIPROT ACCESS NO | O75534 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is upregulated in asthma exacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:64
| ACCESS NO | 100358 |
| GENE | CSF3R |
| DESCRIPTION | Colony stimulating factor 3 receptor |
| NCBI ENTREZ ACCESS NO | 1441 |
| UNIPROT ACCESS NO | Q99062 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in cellular assembly and cell-cell interaction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | BE0000793 |
| MONCLONAL ANTIBODY | Anti-GCSF Receptor for Mouse/Human |
Record No:65
| ACCESS NO | 100372 |
| GENE | Coro1a |
| DESCRIPTION | Coronin 1A |
| NCBI ENTREZ ACCESS NO | 12721 |
| UNIPROT ACCESS NO | O89053 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Occupational asthma induced by chemicals |
| SAMPLE | Auricular lymph nodes |
| TECHNIQUES | 2D DIGE and MALDI-TOF-MS and western blot |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It mediates intracellular calcium release as a result of T-cell activation upon allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23038679 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Coronin 1a for Mouse/Human |
Record No:66
| ACCESS NO | 100379 |
| GENE | Cotl1 |
| DESCRIPTION | Coactosin-like protein |
| NCBI ENTREZ ACCESS NO | 72042 |
| UNIPROT ACCESS NO | Q9CQI6 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | 2D PAGE andLC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20029843 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-COTL1 [AT1D6] for Human |
Record No:67
| ACCESS NO | 100382 |
| GENE | Chi3l4 |
| DESCRIPTION | Chitinase 3-like protein 4 (Ym2) |
| NCBI ENTREZ ACCESS NO | 104183 |
| UNIPROT ACCESS NO | Q91Z98 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | 2D PAGE andLC-MS/MS followed by western blot and r |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in allergic inflammation through the IL-4/STAT 6 signal transduction pathway. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20029843 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:68
| ACCESS NO | 100386 |
| GENE | Chi3l1 |
| DESCRIPTION | Chitinase-3-like protein 1 |
| NCBI ENTREZ ACCESS NO | 12654 |
| UNIPROT ACCESS NO | Q61362 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | 2D PAGE andLC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in allergic inflammation through the IL-4/STAT 6 signal transduction pathway. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20029843 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CHI3L1 for Human |
Record No:69
| ACCESS NO | 100387 |
| GENE | C3 |
| DESCRIPTION | Complement C3 |
| NCBI ENTREZ ACCESS NO | 12266 |
| UNIPROT ACCESS NO | P01027 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | 2D PAGE andLC-MS/MS followed by western blot and r |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | C3 is an acute-phase reactant; an increase in C3 synthesis is induced during acute pulmonary inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20029843 |
| DRUG TARGET | BE0003455 |
| MONCLONAL ANTIBODY | Anti-C3 antibody for Mouse |
Record No:70
| ACCESS NO | 100388 |
| GENE | Chia |
| DESCRIPTION | Acidic mammalian chitinase |
| NCBI ENTREZ ACCESS NO | 81600 |
| UNIPROT ACCESS NO | Q91XA9 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | 2D PAGE andLC-MS/MS followed by western blot and r |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Chitinase 3-like protein 3 (Ym1) |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20029843 |
| DRUG TARGET | BE0001649 |
| MONCLONAL ANTIBODY | N/A |
Record No:71
| ACCESS NO | 100390 |
| GENE | Chi3l3 |
| DESCRIPTION | Chitinase 3-like protein 3 (Ym1) |
| NCBI ENTREZ ACCESS NO | 12655 |
| UNIPROT ACCESS NO | O35744 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | 2D PAGE andLC-MS/MS followed by western blot and r |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in allergic inflammation through the IL-4/STAT 6 signal transduction pathway. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20029843 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:72
| ACCESS NO | 100405 |
| GENE | CCL2 |
| DESCRIPTION | MCP-1 |
| NCBI ENTREZ ACCESS NO | 102135739 |
| UNIPROT ACCESS NO | P61274 |
| ORGANISM | Monkey |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA microarrays and Quantitative RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is a mediator of pulmonary inflammation in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 12049661 |
| DRUG TARGET | BE0001047 |
| MONCLONAL ANTIBODY | N/A |
Record No:73
| ACCESS NO | 100406 |
| GENE | CCL7 |
| DESCRIPTION | MCP-3 |
| NCBI ENTREZ ACCESS NO | 102136132 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Monkey |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA microarrays and Quantitative RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is a mediator of pulmonary inflammation in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 12049661 |
| DRUG TARGET | BE0002941 |
| MONCLONAL ANTIBODY | Anti-MCP3 for Rat/Human |
Record No:74
| ACCESS NO | 100408 |
| GENE | CCL18 |
| DESCRIPTION | Pulmonary and activation-regulated chemokines |
| NCBI ENTREZ ACCESS NO | 102135120 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Monkey |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA microarrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in tissue remodeling. It is significantly modulated by IL4. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 12049661 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 4 for Human |
Record No:75
| ACCESS NO | 100423 |
| GENE | CAPG |
| DESCRIPTION | Capping protein cap G |
| NCBI ENTREZ ACCESS NO | 822 |
| UNIPROT ACCESS NO | P40121 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | bronchial epithelial cells stimulated with TGF bet |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It participates in cell cycle regulation as it mediates communication between the actin cytoskeleton and microtubule-based organelles involved in mitosis. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20219718 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Actin Regulatory Protein CAPG for Mouse/Rat/Human |
Record No:76
| ACCESS NO | 100432 |
| GENE | CEACAM8 |
| DESCRIPTION | Carcinoembryonic antigen - related cell adhesion molecule 8 |
| NCBI ENTREZ ACCESS NO | 1088 |
| UNIPROT ACCESS NO | P31997 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe asthma |
| SAMPLE | CD4 + T cells |
| TECHNIQUES | Microarray and Real time Q-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is upregulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21917308 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD66b for Human |
Record No:77
| ACCESS NO | 100439 |
| GENE | CAMP |
| DESCRIPTION | Cathelicidin antimicrobial peptide |
| NCBI ENTREZ ACCESS NO | 820 |
| UNIPROT ACCESS NO | P49913 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe asthma |
| SAMPLE | CD4 + T cells |
| TECHNIQUES | Microarray and Real time Q-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is upregulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21917308 |
| DRUG TARGET | BE0004543 |
| MONCLONAL ANTIBODY | N/A |
Record No:78
| ACCESS NO | 100441 |
| GENE | CEACAM6 |
| DESCRIPTION | Carcinoembryonic antigen–related cell adhesion molecule 6 |
| NCBI ENTREZ ACCESS NO | 4680 |
| UNIPROT ACCESS NO | P40199 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe asthma |
| SAMPLE | CD4 + T cells |
| TECHNIQUES | Microarray and Real time Q-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is upregulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21917308 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CEACAM6 for Human/Mouse/Rat |
Record No:79
| ACCESS NO | 100442 |
| GENE | CEACAM8 |
| DESCRIPTION | Carcinoembryonic antigen–related cell adhesion molecule 8 |
| NCBI ENTREZ ACCESS NO | 1088 |
| UNIPROT ACCESS NO | P31997 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe asthma |
| SAMPLE | CD8 + T cells |
| TECHNIQUES | Microarray and Real time Q-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is upregulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21917308 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD66b for Human |
Record No:80
| ACCESS NO | 100443 |
| GENE | CHI3L1 |
| DESCRIPTION | Chitinase 3 like 1 (cartilage glycoprotein-39) |
| NCBI ENTREZ ACCESS NO | 1116 |
| UNIPROT ACCESS NO | P36222 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe asthma |
| SAMPLE | CD8 + T cells |
| TECHNIQUES | Microarray and Real time Q-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is upregulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21917308 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CHI3L1 for Human |
Record No:81
| ACCESS NO | 100446 |
| GENE | CD24 |
| DESCRIPTION | CD24 molecule |
| NCBI ENTREZ ACCESS NO | 100133941 |
| UNIPROT ACCESS NO | P25063 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe asthma |
| SAMPLE | CD8 + T cells |
| TECHNIQUES | Microarray and Real time Q-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is upregulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21917308 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD24 for Human |
Record No:82
| ACCESS NO | 100450 |
| GENE | CEACAM6 |
| DESCRIPTION | Carcinoembryonic antigen - related cell adhesion molecule 6 |
| NCBI ENTREZ ACCESS NO | 4680 |
| UNIPROT ACCESS NO | P40199 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe asthma |
| SAMPLE | CD8 + T cells |
| TECHNIQUES | Microarray and Real time Q-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is upregulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21917308 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CEACAM6 for Human/Mouse/Rat |
Record No:83
| ACCESS NO | 100452 |
| GENE | CST1 |
| DESCRIPTION | Cystatin SN |
| NCBI ENTREZ ACCESS NO | 1469 |
| UNIPROT ACCESS NO | P01037 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Respiratory Allergy |
| SAMPLE | Nasal Epithelial Cell |
| TECHNIQUES | Affymetrix microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It encodes a cysteine protease inhibitor. It is known to be associated with pulmonary fibrosis and asthma. |
| GEO_PRIDE_ACCESS_NO | GSE19190 |
| REFERENCE | 22005912 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:84
| ACCESS NO | 100455 |
| GENE | CD44 |
| DESCRIPTION | Neurotrophic tyrosine kinase receptor-type 2 |
| NCBI ENTREZ ACCESS NO | 960 |
| UNIPROT ACCESS NO | P16070 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Respiratory Allergy |
| SAMPLE | Nasal Epithelial Cell |
| TECHNIQUES | Affymetrix microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is clearly associated with basal or mucous cells. It is decreased during in vitro differentiation while all were up-regulated in patients with uncontrolled asthma. |
| GEO_PRIDE_ACCESS_NO | GSE19190 |
| REFERENCE | 22005912 |
| DRUG TARGET | BE0001113 |
| MONCLONAL ANTIBODY | Anti-CD44 for Human/Rat/Mouse |
Record No:85
| ACCESS NO | 100458 |
| GENE | CDH26 |
| DESCRIPTION | Cadherin-like 26 |
| NCBI ENTREZ ACCESS NO | 60437 |
| UNIPROT ACCESS NO | Q8IXH8 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Respiratory Allergy |
| SAMPLE | Nasal Epithelial Cell |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated upon dust mite allergen challenge. |
| GEO_PRIDE_ACCESS_NO | GSE19190 |
| REFERENCE | 22005912 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:86
| ACCESS NO | 100460 |
| GENE | CPA3 |
| DESCRIPTION | Carboxypeptidase A3 |
| NCBI ENTREZ ACCESS NO | 1359 |
| UNIPROT ACCESS NO | P15088 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Respiratory Allergy |
| SAMPLE | Nasal Epithelial Cell |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated upon dust mite allergen challenge. |
| GEO_PRIDE_ACCESS_NO | GSE19190 |
| REFERENCE | 22005912 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:87
| ACCESS NO | 100473 |
| GENE | CCL2 |
| DESCRIPTION | chemokine (C-C motif) ligand 2 |
| NCBI ENTREZ ACCESS NO | 6347 |
| UNIPROT ACCESS NO | P13500 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Airway smooth muscle cell (ASM) line |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is downregulated in ASM after dexamethasone treatment. |
| GEO_PRIDE_ACCESS_NO | GSE3946 |
| REFERENCE | 21257922 |
| DRUG TARGET | BE0001047 |
| MONCLONAL ANTIBODY | N/A |
Record No:88
| ACCESS NO | 100481 |
| GENE | CASP14 |
| DESCRIPTION | Caspase-14 |
| NCBI ENTREZ ACCESS NO | 23581 |
| UNIPROT ACCESS NO | P31944 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis and eczema |
| SAMPLE | Skin tapings |
| TECHNIQUES | nano-HPLC-MS/MS (ion trap) |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. It is required for the processing of deiminated filaggrin to produce free acids that moisturizes the skin. Mutation in this gene results in transepidermal water loss and decreased stratum corneum hydration. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211653 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Caspase-14 [70A1426] for Mouse/Human |
Record No:89
| ACCESS NO | 100482 |
| GENE | CDSN |
| DESCRIPTION | Corneodesmosin |
| NCBI ENTREZ ACCESS NO | 1041 |
| UNIPROT ACCESS NO | Q15517 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis and eczema |
| SAMPLE | Skin tapings |
| TECHNIQUES | nano-HPLC-MS/MS (ion trap) |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is a component of corneodesmosome. Corneodesmosomes bind keratins to the cellular membrane and serve to tightly attach adjacent corneocytes. It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. This lower expression can be an indicative of inappropriate desquamation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211653 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Corneodesmosin for Human |
Record No:90
| ACCESS NO | 100504 |
| GENE | CLCA1 |
| DESCRIPTION | Calcium activated chloride channel family member 1 |
| NCBI ENTREZ ACCESS NO | 1179 |
| UNIPROT ACCESS NO | A8K7I4 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and corticosteroids treatment |
| SAMPLE | Airway epithelial cells |
| TECHNIQUES | microarray-Affymetrix and q-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It functions indirectly in chloride transport and has been reported to be up-regulated in asthma |
| GEO_PRIDE_ACCESS_NO | GSE4302 |
| REFERENCE | 17898169 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CLCA1 for Human/Rabbit/Mouse |
Record No:91
| ACCESS NO | 100506 |
| GENE | CPA3 |
| DESCRIPTION | Carboxy peptidase A3 |
| NCBI ENTREZ ACCESS NO | 1359 |
| UNIPROT ACCESS NO | P15088 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and corticosteroids treatment |
| SAMPLE | Airway epithelial cells |
| TECHNIQUES | microarray-Affymetrix and q-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Expressed in airway mast and basophil cells that lies in epithelial compartment of asthma. It contribute to the epithelial cell activation and dysfunction that characterizes asthma. |
| GEO_PRIDE_ACCESS_NO | GSE4302 |
| REFERENCE | 17898169 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:92
| ACCESS NO | 100511 |
| GENE | Ccl21a |
| DESCRIPTION | Chemokine (C-C motif) ligand 21A (serine) |
| NCBI ENTREZ ACCESS NO | 18829 |
| UNIPROT ACCESS NO | P84444 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung eosinophil |
| TECHNIQUES | Compugen mouse 22K oligonucleotide microarrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Product of this gene is involved in inflammatory cell recruitment. |
| GEO_PRIDE_ACCESS_NO | GSE15345 |
| REFERENCE | 19395375 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:93
| ACCESS NO | 100512 |
| GENE | Chil3 |
| DESCRIPTION | Chitinase-like 3 |
| NCBI ENTREZ ACCESS NO | 12655 |
| UNIPROT ACCESS NO | O35744 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung eosinophil |
| TECHNIQUES | Compugen mouse 22K oligonucleotide microarrays and |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | |
| GEO_PRIDE_ACCESS_NO | GSE15345 |
| REFERENCE | 19395375 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:94
| ACCESS NO | 100524 |
| GENE | Ccl8 |
| DESCRIPTION | Chemokine (C-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 20307 |
| UNIPROT ACCESS NO | Q9Z121 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Macrophages from Broncho Alveolar Lavage (BAL) and |
| TECHNIQUES | Illumina gene chip microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Overexpressed in OVA sensitized mouse. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23685352 |
| DRUG TARGET | BE0002941 |
| MONCLONAL ANTIBODY | Anti-MCP2 for Human |
Record No:95
| ACCESS NO | 100525 |
| GENE | Chi3l4(Ym2) |
| DESCRIPTION | Chitinase 3-like 4 a |
| NCBI ENTREZ ACCESS NO | 104183 |
| UNIPROT ACCESS NO | Q91Z98 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Macrophages from Broncho Alveolar Lavage (BAL) and |
| TECHNIQUES | Illumina gene chip microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is produced by the M2 macrophages present in the airway lumen. This protein along with eotaxin-2 and other chemokines may play an important role in leukocyte migration into asthmatic airways. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23685352 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:96
| ACCESS NO | 100531 |
| GENE | Ccl8 |
| DESCRIPTION | Chemokine (C-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 20307 |
| UNIPROT ACCESS NO | Q9Z121 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Tissue from left lung |
| TECHNIQUES | Affymetrix gene chip cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is a component of chemokine signaling in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18087161 |
| DRUG TARGET | BE0002941 |
| MONCLONAL ANTIBODY | Anti-MCP2 for Human |
Record No:97
| ACCESS NO | 100535 |
| GENE | Clca3 |
| DESCRIPTION | chloride channel calcium activated 3 a |
| NCBI ENTREZ ACCESS NO | 23844 |
| UNIPROT ACCESS NO | Q9D7Z6 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Tissue from left lung |
| TECHNIQUES | Affymetrix gene chip cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Induction of this gene in airway epithelial cell is important for mucus production. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18087161 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:98
| ACCESS NO | 100541 |
| GENE | Cdh11 |
| DESCRIPTION | Cadherin 11 |
| NCBI ENTREZ ACCESS NO | 84407 |
| UNIPROT ACCESS NO | F1MAH6 |
| ORGANISM | Norway brown rat |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Right cranial lung lobe |
| TECHNIQUES | Affymetrix microarray + quantitative PCR(real time |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is responsible for both inflammation and remodeling. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19176365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-OB Cadherin for Human |
Record No:99
| ACCESS NO | 100543 |
| GENE | Cnn1 |
| DESCRIPTION | Calponin 1 |
| NCBI ENTREZ ACCESS NO | 65204 |
| UNIPROT ACCESS NO | Q08290 |
| ORGANISM | Norway brown rat |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Right cranial lung lobe |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is related to smooth muscle and/or the cytoskeleton. Altered expression in asthmatic lungs results in an increase in the proliferation rate of airway smooth muscle (ASM) cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19176365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Calponin for Human/Rat/Mouse |
Record No:100
| ACCESS NO | 100545 |
| GENE | C4bpa |
| DESCRIPTION | Complement component 4 binding protein |
| NCBI ENTREZ ACCESS NO | 24235 |
| UNIPROT ACCESS NO | Q5M891 |
| ORGANISM | Norway brown rat |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Right cranial lung lobe |
| TECHNIQUES | Affymetrix microarray + quantitative PCR(real time |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Downregulated in OVA sensitized rodents exposed to concentrated air particulates. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19176365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-C4BPA for Mouse/Human |
Record No:101
| ACCESS NO | 100550 |
| GENE | Col11a1 |
| DESCRIPTION | Collagen type 11 |
| NCBI ENTREZ ACCESS NO | 12814 |
| UNIPROT ACCESS NO | Q61245 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Tissue from bronchial biopsy |
| TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is an extracellular protein involved in remodelling. |
| GEO_PRIDE_ACCESS_NO | GSE15823 |
| REFERENCE | 15038835 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-COL11A1 for Human |
Record No:102
| ACCESS NO | 100558 |
| GENE | Cpa3 |
| DESCRIPTION | Carboxypeptidase A3 (mast cell) |
| NCBI ENTREZ ACCESS NO | 12873 |
| UNIPROT ACCESS NO | P15089 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Tissue from bronchial biopsy |
| TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It encodes for a proteolytic enzyme from mast cell and upregulated in asthma (data collected from supplementary table). |
| GEO_PRIDE_ACCESS_NO | GSE15823 |
| REFERENCE | 15038835 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CPA3 for Human |
Record No:103
| ACCESS NO | 100560 |
| GENE | Cybb |
| DESCRIPTION | Cytochrome b-245-beta polypeptide |
| NCBI ENTREZ ACCESS NO | 13058 |
| UNIPROT ACCESS NO | Q61093 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Tissue from bronchial biopsy |
| TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | biomarkers of allergic inflammation (data collected from supplementary table). |
| GEO_PRIDE_ACCESS_NO | GSE15823 |
| REFERENCE | 15038835 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-NOX2/gp91 phox for Human/Rat/Mouse |
Record No:104
| ACCESS NO | 100574 |
| GENE | Cxcl15 |
| DESCRIPTION | Lungkine |
| NCBI ENTREZ ACCESS NO | 20309 |
| UNIPROT ACCESS NO | Q9WVL7 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic inflammation |
| SAMPLE | Bronchoalveolar lavage fluid |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Neutrophil chemoattractants. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17082650 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CXCL15 for Mouse |
Record No:105
| ACCESS NO | 100576 |
| GENE | Chi3l3 |
| DESCRIPTION | YM1(Chitinase-3-like protein 4) |
| NCBI ENTREZ ACCESS NO | 12655 |
| UNIPROT ACCESS NO | O35744 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic inflammation |
| SAMPLE | Bronchoalveolar lavage fluid |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS; real-time PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Eosinophil chemoattractant. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17082650 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:106
| ACCESS NO | 100577 |
| GENE | Chi3l4 |
| DESCRIPTION | YM2(Chitinase-3-like protein 4) |
| NCBI ENTREZ ACCESS NO | 104183 |
| UNIPROT ACCESS NO | Q91Z98 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic inflammation |
| SAMPLE | Bronchoalveolar lavage fluid |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS; real-time PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Involved in tissue remodelling and is expressed in the epithelium. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17082650 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:107
| ACCESS NO | 100578 |
| GENE | Cxcl15 |
| DESCRIPTION | Lungkine |
| NCBI ENTREZ ACCESS NO | 20309 |
| UNIPROT ACCESS NO | Q9WVL7 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic airway inflammation |
| SAMPLE | Bronchoalveolar lavage fluid |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS; real-time PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Regulates neutrophil migration into lungs and is present in bronchoepithelial cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15996009 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CXCL15 for Mouse |
Record No:108
| ACCESS NO | 100579 |
| GENE | Chia |
| DESCRIPTION | Chitinase |
| NCBI ENTREZ ACCESS NO | 81600 |
| UNIPROT ACCESS NO | Q91XA9 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic airway inflammation |
| SAMPLE | Bronchoalveolar lavage fluid |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS; real-time PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Local matrix proteins involved in increased mucus production and maintenance of airway function |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15996009 |
| DRUG TARGET | BE0001649 |
| MONCLONAL ANTIBODY | N/A |
Record No:109
| ACCESS NO | 100580 |
| GENE | Chi3l3 |
| DESCRIPTION | YM1(Chitinase-3-like protein 4) |
| NCBI ENTREZ ACCESS NO | 12655 |
| UNIPROT ACCESS NO | O35744 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic airway inflammation |
| SAMPLE | Bronchoalveolar lavage fluid |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS; real-time PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Eosinophil chemoattractant. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15996009 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:110
| ACCESS NO | 100581 |
| GENE | Chi3l4 |
| DESCRIPTION | YM2(Chitinase-3-like protein 4) |
| NCBI ENTREZ ACCESS NO | 104183 |
| UNIPROT ACCESS NO | Q91Z98 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic airway inflammation |
| SAMPLE | Bronchoalveolar lavage fluid |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS; real-time PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Markedly increased after OVA challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15996009 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:111
| ACCESS NO | 100582 |
| GENE | Clca3 |
| DESCRIPTION | gob-5(Calcium-activated chloride channel regulator 1) |
| NCBI ENTREZ ACCESS NO | 23844 |
| UNIPROT ACCESS NO | Q9D7Z6 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic airway inflammation |
| SAMPLE | Bronchoalveolar lavage fluid |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS; real-time PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Plays a major role in export of chloride ions which leads to mucin secretion from airway epithelial cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15996009 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:112
| ACCESS NO | 100586 |
| GENE | CST4 |
| DESCRIPTION | CystatinS |
| NCBI ENTREZ ACCESS NO | 1472 |
| UNIPROT ACCESS NO | P01036 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Seasonal allergic rhinitis |
| SAMPLE | Nasal Lavage Fluid |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Protease inhibitors involved in airway remodeling. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16457599 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Cystatin A for Mouse/Human |
Record No:113
| ACCESS NO | 100588 |
| GENE | CD14 |
| DESCRIPTION | Monocyte differentiation antigen |
| NCBI ENTREZ ACCESS NO | 929 |
| UNIPROT ACCESS NO | P08571 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after segmental allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD14 for Human/Rat/Mouse |
Record No:114
| ACCESS NO | 100590 |
| GENE | CLC |
| DESCRIPTION | Charcot-Leyden crystal protein |
| NCBI ENTREZ ACCESS NO | 1178 |
| UNIPROT ACCESS NO | Q05315 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is an eosinophil granule specific protein produced after eosinophil activation in airways |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0001886+BE0000765+ |
| MONCLONAL ANTIBODY | Anti-CLCN3 for Human/Rat/Mouse |
Record No:115
| ACCESS NO | 100591 |
| GENE | CFH |
| DESCRIPTION | Complement factor H |
| NCBI ENTREZ ACCESS NO | 3075 |
| UNIPROT ACCESS NO | P08603 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Part of the complement cascade pathway and upregulated after allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:116
| ACCESS NO | 100592 |
| GENE | CFB |
| DESCRIPTION | Complement factor B preproprotein |
| NCBI ENTREZ ACCESS NO | 629 |
| UNIPROT ACCESS NO | P00751 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Part of the complement cascade pathway and upregulated after allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0001701 |
| MONCLONAL ANTIBODY | Anti-Factor B for Human |
Record No:117
| ACCESS NO | 100594 |
| GENE | CAT |
| DESCRIPTION | Catalase |
| NCBI ENTREZ ACCESS NO | 847 |
| UNIPROT ACCESS NO | P04040 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0001207 |
| MONCLONAL ANTIBODY | Anti-beta Catenin for Human/Rat/Mouse |
Record No:118
| ACCESS NO | 100602 |
| GENE | CP |
| DESCRIPTION | Ceruloplasmin |
| NCBI ENTREZ ACCESS NO | 1356 |
| UNIPROT ACCESS NO | P00450 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | A serum protein which is a biomarkers of allergic inflammation |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0001140 |
| MONCLONAL ANTIBODY | Anti-CPT1A for Mouse/Rat/Human |
Record No:119
| ACCESS NO | 100618 |
| GENE | CCL11 |
| DESCRIPTION | Eotaxin |
| NCBI ENTREZ ACCESS NO | 6356 |
| UNIPROT ACCESS NO | P51671 |
| ORGANISM | Â Human |
| DISEASE PHENOTYPE | Allergic Inflammation |
| SAMPLE | Airway smooth muscle cells |
| TECHNIQUES | Chip assay/western blotting/EMSA |
| OMICS | Epigenetics |
| STUDY | Low Throughput |
| COMMENTS | It is a major eosinophil chemoattractant whose gene expression is controlled by selective histone H4 acetylation on lysines 5 and 12 at the eotaxin promoter |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15972682 |
| DRUG TARGET | BE0003389 |
| MONCLONAL ANTIBODY | Anti-Eotaxin for Human |
Record No:120
| ACCESS NO | 100631 |
| GENE | C4 |
| DESCRIPTION | Complement component 4B |
| NCBI ENTREZ ACCESS NO | 721 |
| UNIPROT ACCESS NO | P0C0L5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
| SAMPLE | Nasal fluid |
| TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Enriched in acute phase response pathway. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21887273 |
| DRUG TARGET | BE0004686 |
| MONCLONAL ANTIBODY | Anti-C4 for Human |
Record No:121
| ACCESS NO | 100632 |
| GENE | C5 |
| DESCRIPTION | Complement component 5 |
| NCBI ENTREZ ACCESS NO | 727 |
| UNIPROT ACCESS NO | P01031 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
| SAMPLE | Nasal fluid |
| TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Enriched in acute phase response pathway. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21887273 |
| DRUG TARGET | BE0000855 |
| MONCLONAL ANTIBODY | Anti-C5 / C5b for Human |
Record No:122
| ACCESS NO | 100633 |
| GENE | C3 |
| DESCRIPTION | Complement component 3 |
| NCBI ENTREZ ACCESS NO | 718 |
| UNIPROT ACCESS NO | P01024 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
| SAMPLE | Nasal fluid |
| TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Enriched in acute phase response pathway. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21887273 |
| DRUG TARGET | BE0003455 |
| MONCLONAL ANTIBODY | Anti-C3 for Human |
Record No:123
| ACCESS NO | 100634 |
| GENE | CP |
| DESCRIPTION | Ceruloplasmin |
| NCBI ENTREZ ACCESS NO | 1356 |
| UNIPROT ACCESS NO | P00450 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
| SAMPLE | Nasal fluid |
| TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Enriched in acute phase response pathway. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21887273 |
| DRUG TARGET | BE0001140 |
| MONCLONAL ANTIBODY | Anti-Ceruloplasmin for Human |
Record No:124
| ACCESS NO | 100643 |
| GENE | CTSD |
| DESCRIPTION | Cathepsin D |
| NCBI ENTREZ ACCESS NO | 1509 |
| UNIPROT ACCESS NO | P07339 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
| SAMPLE | Nasal fluid |
| TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Significantly decreased after glucocorticoid treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21887273 |
| DRUG TARGET | BE0000941 |
| MONCLONAL ANTIBODY | Anti-Cathepsin D for Mouse/Human |
Record No:125
| ACCESS NO | 100644 |
| GENE | CP |
| DESCRIPTION | Ceruloplasmin |
| NCBI ENTREZ ACCESS NO | 1356 |
| UNIPROT ACCESS NO | P00450 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma proteins |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Copper protein synthesized by the liver and activated by macrophages. Plays a role in iron metabolism and upregulated in adults suffering from asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21471098 |
| DRUG TARGET | BE0001140 |
| MONCLONAL ANTIBODY | Anti-Ceruloplasmin for Human |
Record No:126
| ACCESS NO | 100656 |
| GENE | CFH |
| DESCRIPTION | Complement factor H |
| NCBI ENTREZ ACCESS NO | 3075 |
| UNIPROT ACCESS NO | P08603 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma proteins |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Involved in complement pathways. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21471098 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:127
| ACCESS NO | 100657 |
| GENE | CFB |
| DESCRIPTION | Complement factor B |
| NCBI ENTREZ ACCESS NO | 629 |
| UNIPROT ACCESS NO | P00751 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma proteins |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in complement pathways. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21471098 |
| DRUG TARGET | BE0001701 |
| MONCLONAL ANTIBODY | Anti-Complement factor B for Human |
Record No:128
| ACCESS NO | 100658 |
| GENE | C3 |
| DESCRIPTION | Complement 3 |
| NCBI ENTREZ ACCESS NO | 718 |
| UNIPROT ACCESS NO | P01024 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma proteins |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in complement pathways. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21471098 |
| DRUG TARGET | BE0003455 |
| MONCLONAL ANTIBODY | Anti-C3 for Human |
Record No:129
| ACCESS NO | 100659 |
| GENE | C4A |
| DESCRIPTION | Complement component C4-A |
| NCBI ENTREZ ACCESS NO | 720 |
| UNIPROT ACCESS NO | P0C0L4 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma proteins |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in complement pathways. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21471098 |
| DRUG TARGET | BE0004685 |
| MONCLONAL ANTIBODY | Anti-C4a for Human |
Record No:130
| ACCESS NO | 100672 |
| GENE | Clic5 |
| DESCRIPTION | Chloride intracellular channel protein 5 |
| NCBI ENTREZ ACCESS NO | 224796 |
| UNIPROT ACCESS NO | Q8BXK9 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in chronic asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CLIC5 for Human |
Record No:131
| ACCESS NO | 100686 |
| GENE | Calr |
| DESCRIPTION | Calreticulin |
| NCBI ENTREZ ACCESS NO | 12317 |
| UNIPROT ACCESS NO | P14211 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof and ELISA |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Downregulated in Mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | BE0002109 |
| MONCLONAL ANTIBODY | Anti-Calreticulin for Mouse/Rat/Human/Monkey |
Record No:132
| ACCESS NO | 100689 |
| GENE | Ca2 |
| DESCRIPTION | Carbonic anhydrase 2 |
| NCBI ENTREZ ACCESS NO | 12349 |
| UNIPROT ACCESS NO | P00920 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergen induced asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | BE0000322 |
| MONCLONAL ANTIBODY | Anti-Carbonic Anhydrase II for Mouse/Rat/Human |
Record No:133
| ACCESS NO | 100691 |
| GENE | Chi3l4 |
| DESCRIPTION | YM2 |
| NCBI ENTREZ ACCESS NO | 104183 |
| UNIPROT ACCESS NO | Q91Z98 |
| ORGANISM | TSLP TG mice and BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid Broncho Alveol |
| TECHNIQUES | LC-MS/MS and Western blot and qRT PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Members of the chitinase family and have chemotactic activity for eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22837640 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:134
| ACCESS NO | 100694 |
| GENE | Clca3 |
| DESCRIPTION | Calcium-activated chloride channel regulator |
| NCBI ENTREZ ACCESS NO | 23844 |
| UNIPROT ACCESS NO | Q9D7Z6 |
| ORGANISM | TSLP TG mice and BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid Broncho Alveol |
| TECHNIQUES | LC-MS/MS and Western blot and qRT PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Expressed early in asthma pathogenesis. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22837640 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:135
| ACCESS NO | 100698 |
| GENE | Chia |
| DESCRIPTION | Acidic mammalian chitinase |
| NCBI ENTREZ ACCESS NO | 81600 |
| UNIPROT ACCESS NO | Q91XA9 |
| ORGANISM | TSLP TG mice and BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid Broncho Alveol |
| TECHNIQUES | LC-MS/MS and Western blot and qRT PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Highly expressed in allergic lung but were downregulated after Dexamethasone treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22837640 |
| DRUG TARGET | BE0001649 |
| MONCLONAL ANTIBODY | N/A |
Record No:136
| ACCESS NO | 100699 |
| GENE | Chi3l3 |
| DESCRIPTION | chitinase 3-like 3 |
| NCBI ENTREZ ACCESS NO | 12655 |
| UNIPROT ACCESS NO | O35744 |
| ORGANISM | TSLP TG mice and BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid Broncho Alveol |
| TECHNIQUES | LC-MS/MS and Western blot and qRT PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Downregulated after Dexamethasone treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22837640 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:137
| ACCESS NO | 100711 |
| GENE | C3a |
| DESCRIPTION | Activated complement component 3 |
| NCBI ENTREZ ACCESS NO | 718 |
| UNIPROT ACCESS NO | P01024 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Sputum |
| TECHNIQUES | LC-MS/MS and western blot |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Important chemoattractant for recruitment of leucocytes and upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21906793 |
| DRUG TARGET | BE0003455 |
| MONCLONAL ANTIBODY | Anti-C3 / C3a for Human |
Record No:138
| ACCESS NO | 100715 |
| GENE | CCL2 |
| DESCRIPTION | Chemokine (C-C motif) ligand 2 |
| NCBI ENTREZ ACCESS NO | 6347 |
| UNIPROT ACCESS NO | P13500 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis treatment with glucocorticoid |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | iTRAQ based proteomics nano LC MS/MS gene expressi |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | An extracellular gene in nasal polyps involved in chemokine signalling and is upregulated in allergic patients and also after glucocorticoid treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20659080 |
| DRUG TARGET | BE0001047 |
| MONCLONAL ANTIBODY | N/A |
Record No:139
| ACCESS NO | 100717 |
| GENE | CXCL6 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 6 |
| NCBI ENTREZ ACCESS NO | 6372 |
| UNIPROT ACCESS NO | P80162 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis treatment with glucocorticoid |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | iTRAQ based proteomics nano LC MS/MS gene expressi |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | A chemoattractant responsible for attracting T cells and eosinophils and is decreased after glucocorticoid treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20659080 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GCP2 for Human |
Record No:140
| ACCESS NO | 100719 |
| GENE | CST1 |
| DESCRIPTION | Cystatin SN |
| NCBI ENTREZ ACCESS NO | 1469 |
| UNIPROT ACCESS NO | P01037 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis treatment with glucocorticoid |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | iTRAQ based proteomics and nano LC MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in nasal fluid following Glucocorticoid treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20659080 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Cystatin SN for Human |
Record No:141
| ACCESS NO | 100720 |
| GENE | CST4 |
| DESCRIPTION | Cystatin S |
| NCBI ENTREZ ACCESS NO | 1472 |
| UNIPROT ACCESS NO | P01036 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis treatment with glucocorticoid |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | iTRAQ based proteomics and nano LC MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in nasal fluid following Glucocorticoid treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20659080 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Cystatin S for Human |
Record No:142
| ACCESS NO | 100721 |
| GENE | CST5 |
| DESCRIPTION | Cystatin D |
| NCBI ENTREZ ACCESS NO | 1473 |
| UNIPROT ACCESS NO | P28325 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis treatment with glucocorticoid |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | iTRAQ based proteomics and nano LC MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in nasal fluid following Glucocorticoid treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20659080 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:143
| ACCESS NO | 100722 |
| GENE | CD5L |
| DESCRIPTION | CD5L |
| NCBI ENTREZ ACCESS NO | 922 |
| UNIPROT ACCESS NO | O43866 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Blood plasma |
| TECHNIQUES | MALDI TOF MS and LC-MS/MS and Western Blot |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Helps in macrophage survival and binds to several cells of the immune system. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19116453 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD5L for Human |
Record No:144
| ACCESS NO | 100729 |
| GENE | C4B |
| DESCRIPTION | Complement component 4B |
| NCBI ENTREZ ACCESS NO | 721 |
| UNIPROT ACCESS NO | P0C0L5Â |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Blood plasma |
| TECHNIQUES | MALDI TOF MS and LC-MS/MS and Western Blot |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in atopic dermatitis patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19116453 |
| DRUG TARGET | BE0004686 |
| MONCLONAL ANTIBODY | Anti-C4b for Human |
Record No:145
| ACCESS NO | 100732 |
| GENE | C3 |
| DESCRIPTION | Complement component 3 |
| NCBI ENTREZ ACCESS NO | 718 |
| UNIPROT ACCESS NO | P01024 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma challenged with inhaled allergens |
| SAMPLE | Blood plasma |
| TECHNIQUES | 2D gel and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in immediate phase reaction of allergic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19076930 |
| DRUG TARGET | BE0003455 |
| MONCLONAL ANTIBODY | Anti-C3 for Human/Mouse |
Record No:146
| ACCESS NO | 100733 |
| GENE | C4A |
| DESCRIPTION | Complement C4a fragment |
| NCBI ENTREZ ACCESS NO | 720 |
| UNIPROT ACCESS NO | P0C0L4 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma challenged with inhaled allergens |
| SAMPLE | Blood plasma |
| TECHNIQUES | 2D gel and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in immediate phase reaction of allergic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19076930 |
| DRUG TARGET | BE0004685 |
| MONCLONAL ANTIBODY | Anti-C4a for Human |
Record No:147
| ACCESS NO | 100734 |
| GENE | C3D |
| DESCRIPTION | Complement C3d fragment |
| NCBI ENTREZ ACCESS NO | N/A |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma challenged with inhaled allergens |
| SAMPLE | Blood plasma |
| TECHNIQUES | 2D gel and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in immediate phase reaction of allergic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19076930 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:148
| ACCESS NO | 100745 |
| GENE | CCT5 |
| DESCRIPTION | Chaperonin containing TCP1 subunit 5 |
| NCBI ENTREZ ACCESS NO | 22948 |
| UNIPROT ACCESS NO | P48643 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Perpheral blood mononuclear cells |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved with cell proliferation and apoptosis and was found to be decreased in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21966607 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TCP1 for Mouse/Rat/Human |
Record No:149
| ACCESS NO | 100748 |
| GENE | Cflar |
| DESCRIPTION | CASP8 and FADD-like apoptosis regulator precursor |
| NCBI ENTREZ ACCESS NO | 12633 |
| UNIPROT ACCESS NO | O35732 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in regulation of apoptosis.Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-FLIP for Mouse/Rat/Human |
Record No:150
| ACCESS NO | 100765 |
| GENE | Cd45 |
| DESCRIPTION | Leukocyte common antigen |
| NCBI ENTREZ ACCESS NO | 19264 |
| UNIPROT ACCESS NO | Q8C6Q7 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after allergen challenge.Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD45 for Mouse/Human |
Record No:151
| ACCESS NO | 100766 |
| GENE | Cd94 |
| DESCRIPTION | CD94 antigen |
| NCBI ENTREZ ACCESS NO | 16643 |
| UNIPROT ACCESS NO | O54707 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after allergen challenge.Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD94 for Human |
Record No:152
| ACCESS NO | 100769 |
| GENE | Cx3cr1 |
| DESCRIPTION | CX3C chemokine receptor 1 |
| NCBI ENTREZ ACCESS NO | 13051 |
| UNIPROT ACCESS NO | Q9Z0D9 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in immune cell trafficking and cell movement.Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CX3CR1 for Human |
Record No:153
| ACCESS NO | 100770 |
| GENE | Cbp |
| DESCRIPTION | Cytohesin binding protein |
| NCBI ENTREZ ACCESS NO | 227929 |
| UNIPROT ACCESS NO | Q91VY6 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after allergen challenge.Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:154
| ACCESS NO | 100772 |
| GENE | CCL15 |
| DESCRIPTION | Chemokine (C-C motif) ligand 15 |
| NCBI ENTREZ ACCESS NO | 6359 |
| UNIPROT ACCESS NO | |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Airway smooth muscle cells |
| TECHNIQUES | Real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Chemoattractant for eosinophils |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22092970 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Macrophage inflammatory protein 5 for Human |
Record No:155
| ACCESS NO | 100775 |
| GENE | CHI3L3 |
| DESCRIPTION | chitinase 3-like 3 |
| NCBI ENTREZ ACCESS NO | N/A |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | DNA |
| TECHNIQUES | Illumina Human Hap 550Kv3 BeadChip SNP array |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | rs4950928 is a risk allele in this gene. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19264973 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:156
| ACCESS NO | 100777 |
| GENE | CTLA4 |
| DESCRIPTION | Cytotoxic T-lymphocyte-associated protein 4 |
| NCBI ENTREZ ACCESS NO | 1493 |
| UNIPROT ACCESS NO | P16410 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | DNA |
| TECHNIQUES | Illumina Human Hap 550Kv3 BeadChip SNP array |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | SNP in this gene is associated with asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19264973 |
| DRUG TARGET | BE0000887 |
| MONCLONAL ANTIBODY | Anti-CTLA4 for Human/Mouse/Rat |
Record No:157
| ACCESS NO | 100791 |
| GENE | C1qa |
| DESCRIPTION | Complement C1q Subcomponent subunit A |
| NCBI ENTREZ ACCESS NO | 12259 |
| UNIPROT ACCESS NO | P98086 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Part of the complement cascade pathway and is upregulated in both short and long exposure to allergens. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0002094 |
| MONCLONAL ANTIBODY | Anti-C1QA for Human |
Record No:158
| ACCESS NO | 100792 |
| GENE | C1qb |
| DESCRIPTION | Complement C1q Subcomponent subunit B |
| NCBI ENTREZ ACCESS NO | 12260 |
| UNIPROT ACCESS NO | P14106 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Subunits of C1q complex and is upregulated in murine model of acute and chronic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0002095 |
| MONCLONAL ANTIBODY | Anti-C1QB for Human |
Record No:159
| ACCESS NO | 100793 |
| GENE | C1qc |
| DESCRIPTION | Complement C1q Subcomponent subunit C |
| NCBI ENTREZ ACCESS NO | 12262 |
| UNIPROT ACCESS NO | Q02105 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Subunits of C1q complex and is upregulated in murine model of acute and chronic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0002096 |
| MONCLONAL ANTIBODY | Anti-C1QC for Human |
Record No:160
| ACCESS NO | 100794 |
| GENE | Camp |
| DESCRIPTION | Cathelicidin antimicrobial peptide |
| NCBI ENTREZ ACCESS NO | 12796 |
| UNIPROT ACCESS NO | P51437 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in both acute and chronic murine asthma models. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0004543 |
| MONCLONAL ANTIBODY | Anti-Cathelicidin for Human |
Record No:161
| ACCESS NO | 100795 |
| GENE | Ccna |
| DESCRIPTION | Cyclin A-2 |
| NCBI ENTREZ ACCESS NO | 12428 |
| UNIPROT ACCESS NO | P51943 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in short allergen exposure whereas downregulated in long exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Cyclin A for Human/Mouse |
Record No:162
| ACCESS NO | 100796 |
| GENE | Ccnb2 |
| DESCRIPTION | cyclin B2 |
| NCBI ENTREZ ACCESS NO | 12442 |
| UNIPROT ACCESS NO | P30276 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in short allergen exposure whereas downregulated in long exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Cyclin B2 for Mouse/Human/Rat |
Record No:163
| ACCESS NO | 100797 |
| GENE | CD163 |
| DESCRIPTION | Scavenger receptor cysteine rich type 1 protein M130 |
| NCBI ENTREZ ACCESS NO | 93671 |
| UNIPROT ACCESS NO | B7ZMW6 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in both short and long term exposure to allergen in mouse model of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0003375 |
| MONCLONAL ANTIBODY | Anti-CD163 for Human |
Record No:164
| ACCESS NO | 100798 |
| GENE | Cd209e |
| DESCRIPTION | CD209e antigen |
| NCBI ENTREZ ACCESS NO | 170780 |
| UNIPROT ACCESS NO | Q91ZW7 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in short and long term but highly expressed in long term allergen exposure. Plays important role in dendritic cells-T cells interaction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:165
| ACCESS NO | 100799 |
| GENE | Cdc2a |
| DESCRIPTION | Cell division control protein 2 homolog |
| NCBI ENTREZ ACCESS NO | 12534 |
| UNIPROT ACCESS NO | P11440 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Observed to be upregulated in short and downregulated in long antigen exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:166
| ACCESS NO | 100800 |
| GENE | Cdca3 |
| DESCRIPTION | Cell division cycle associated protein 3 |
| NCBI ENTREZ ACCESS NO | 14793 |
| UNIPROT ACCESS NO | Q99M54 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Observed to be upregulated in short and downregulated in long antigen exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CDCA3 for Mouse/Rat/Human |
Record No:167
| ACCESS NO | 100801 |
| GENE | Cdca8 |
| DESCRIPTION | Borealin |
| NCBI ENTREZ ACCESS NO | 52276 |
| UNIPROT ACCESS NO | Q8BHX3 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in short term and downregulated in long term allergen exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:168
| ACCESS NO | 100802 |
| GENE | Cks2 |
| DESCRIPTION | Cyclin dependant kinase regulatory subunit2 |
| NCBI ENTREZ ACCESS NO | 66197 |
| UNIPROT ACCESS NO | P56390 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in short time allergen exposure and downregulated in long exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CKS2 for Mouse/Rat/Human |
Record No:169
| ACCESS NO | 100803 |
| GENE | Col6a |
| DESCRIPTION | collagen type VI alpha 1 |
| NCBI ENTREZ ACCESS NO | 12833 |
| UNIPROT ACCESS NO | Q04857 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in both short and long time allergen exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:170
| ACCESS NO | 100804 |
| GENE | Cp |
| DESCRIPTION | Ceruloplasmin |
| NCBI ENTREZ ACCESS NO | 12870 |
| UNIPROT ACCESS NO | Q61147 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. It is upregulated in chronic and acute asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0001140 |
| MONCLONAL ANTIBODY | Anti-Ceruloplasmin for Human |
Record No:171
| ACCESS NO | 100822 |
| GENE | Col3a1 |
| DESCRIPTION | Collagen type III alpha 1 |
| NCBI ENTREZ ACCESS NO | 12825 |
| UNIPROT ACCESS NO | P08121 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in collagen deposition |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0002130 |
| MONCLONAL ANTIBODY | Anti-Collagen III for Rat/Human |
Record No:172
| ACCESS NO | 100825 |
| GENE | Capn9 |
| DESCRIPTION | Calpain 9 |
| NCBI ENTREZ ACCESS NO | 73647 |
| UNIPROT ACCESS NO | Q9D805 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthma |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Calpain 9 for Human |
Record No:173
| ACCESS NO | 100831 |
| GENE | Ccl8 |
| DESCRIPTION | CC motif chemokine 8 |
| NCBI ENTREZ ACCESS NO | 20307 |
| UNIPROT ACCESS NO | Q9Z121 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Constant expression in both short and long term allergen exposure to mouse. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0002941 |
| MONCLONAL ANTIBODY | Anti-MCP2 for Mouse/Human |
Record No:174
| ACCESS NO | 100832 |
| GENE | Ccl11 |
| DESCRIPTION | Eotaxin |
| NCBI ENTREZ ACCESS NO | 20292 |
| UNIPROT ACCESS NO | P48298 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Constant expression in both short and long term allergen exposure to mouse. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0003389 |
| MONCLONAL ANTIBODY | Anti-Eotaxin for Human |
Record No:175
| ACCESS NO | 100833 |
| GENE | Chi3l3 |
| DESCRIPTION | Chitinase 3 like protein 3 |
| NCBI ENTREZ ACCESS NO | 104183 |
| UNIPROT ACCESS NO | Q91Z98 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Produced by epithelial and immune cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CHI3L1 for Human |
Record No:176
| ACCESS NO | 100834 |
| GENE | Chia |
| DESCRIPTION | Acidic mammalian chitinase |
| NCBI ENTREZ ACCESS NO | 81600 |
| UNIPROT ACCESS NO | Q91XA9 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in asthmatic mouse. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0001649 |
| MONCLONAL ANTIBODY | N/A |
Record No:177
| ACCESS NO | 100846 |
| GENE | Ccl2 |
| DESCRIPTION | chemokine (C-C motif) ligand 2 |
| NCBI ENTREZ ACCESS NO | 20296 |
| UNIPROT ACCESS NO | P10148 |
| ORGANISM | SWR/J mouse |
| DISEASE PHENOTYPE | Allergic conjunctivitis |
| SAMPLE | Conjunctival Tissues |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in conjuctiva after allergen exposure in mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18658092 |
| DRUG TARGET | BE0001047 |
| MONCLONAL ANTIBODY | Anti-MCP1 for Mouse/Rat/Human |
Record No:178
| ACCESS NO | 100847 |
| GENE | CCR3 |
| DESCRIPTION | chemokine (C-C motif) receptor 3 |
| NCBI ENTREZ ACCESS NO | 12771 |
| UNIPROT ACCESS NO | P51678 |
| ORGANISM | SWR/J mouse |
| DISEASE PHENOTYPE | Allergic conjunctivitis |
| SAMPLE | Conjunctival Tissues |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Regulates eosinophilic inflammation and mast cell degranulation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18658092 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CCR3 for Mouse/Rat/Human |
Record No:179
| ACCESS NO | 100854 |
| GENE | CCR5 |
| DESCRIPTION | Chemokine receptor 5 |
| NCBI ENTREZ ACCESS NO | 1234 |
| UNIPROT ACCESS NO | P51681 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Affymetrix oligonucleotide microarray and RTPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Overexpressed in patients suffering from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | BE0000911 |
| MONCLONAL ANTIBODY | Anti-CCR5 for Mouse/Rat/Human |
Record No:180
| ACCESS NO | 100857 |
| GENE | CD80 |
| DESCRIPTION | CD80 antigen |
| NCBI ENTREZ ACCESS NO | 941 |
| UNIPROT ACCESS NO | P33681 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Affymetrix oligonucleotide microarray and RTPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in patients suffering from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | BE0000847 |
| MONCLONAL ANTIBODY | Anti-CD80 for Mouse/Human |
Record No:181
| ACCESS NO | 100858 |
| GENE | CD86 |
| DESCRIPTION | CD86 antigen |
| NCBI ENTREZ ACCESS NO | 942 |
| UNIPROT ACCESS NO | P42081 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Affymetrix oligonucleotide microarray and RTPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in patients suffering from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | BE0000846 |
| MONCLONAL ANTIBODY | Anti-CD86 for Rat/Human |
Record No:182
| ACCESS NO | 100860 |
| GENE | CCL5 |
| DESCRIPTION | Chemokine (C-C motif) ligand 5 |
| NCBI ENTREZ ACCESS NO | 6352 |
| UNIPROT ACCESS NO | P13501 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Associated with activation and development of Th2 cells. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | BE0000975 |
| MONCLONAL ANTIBODY | Anti-RANTES for Human |
Record No:183
| ACCESS NO | 100861 |
| GENE | CCL13 |
| DESCRIPTION | Chemokine (C-C motif) ligand 13 |
| NCBI ENTREZ ACCESS NO | 6357 |
| UNIPROT ACCESS NO | Q99616 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Affects the TH1/TH2 balance by enhancing TH2 responses. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MCP4 for Human |
Record No:184
| ACCESS NO | 100862 |
| GENE | CCL14 |
| DESCRIPTION | Chemokine (C-C motif) ligand 14 |
| NCBI ENTREZ ACCESS NO | 6358 |
| UNIPROT ACCESS NO | Q16627 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Associated with activation and development of TH2 cells. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CCL14 for Human |
Record No:185
| ACCESS NO | 100863 |
| GENE | CCL18 |
| DESCRIPTION | Chemokine (C-C motif) ligand 18 |
| NCBI ENTREZ ACCESS NO | 6362 |
| UNIPROT ACCESS NO | P55774 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Associated with activation and development of TH2 cells. Selected based on gold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 4 for Human |
Record No:186
| ACCESS NO | 100864 |
| GENE | CCL19 |
| DESCRIPTION | Chemokine (C-C motif) ligand 19 |
| NCBI ENTREZ ACCESS NO | 6363 |
| UNIPROT ACCESS NO | Q99731 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Associated with activation and development of TH2 cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 3 beta for Human |
Record No:187
| ACCESS NO | 100865 |
| GENE | CCL24 |
| DESCRIPTION | Chemokine (C-C motif) ligand 24 |
| NCBI ENTREZ ACCESS NO | 6369 |
| UNIPROT ACCESS NO | O00175 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Helps eosinophils to move to local inflammation site. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:188
| ACCESS NO | 100866 |
| GENE | CXCL10 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 10 |
| NCBI ENTREZ ACCESS NO | 3627 |
| UNIPROT ACCESS NO | P02778 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in nasal mucosa of allergic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | Anti-IP10 for Mouse/Human |
Record No:189
| ACCESS NO | 100867 |
| GENE | CCR4 |
| DESCRIPTION | Chemokine (C-C motif) receptor 4 |
| NCBI ENTREZ ACCESS NO | 1233 |
| UNIPROT ACCESS NO | P51679 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Chemokine receptors expressed on eosinophils as well as mast cells and basophils. Highly expressed. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CCR4 for Human |
Record No:190
| ACCESS NO | 100868 |
| GENE | CCR8 |
| DESCRIPTION | Chemokine (C-C motif) receptor 8 |
| NCBI ENTREZ ACCESS NO | 1237 |
| UNIPROT ACCESS NO | P51685 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Chemokine receptors expressed on eosinophils as well as mast cells and basophils. Upregulated and selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CCR8 for Rat/Human |
Record No:191
| ACCESS NO | 100869 |
| GENE | CX3CR1 |
| DESCRIPTION | C-X-C chemokine receptor type 1 |
| NCBI ENTREZ ACCESS NO | 3577 |
| UNIPROT ACCESS NO | P25024 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Functions both as a chemoattractant and adhesion molecule. Upregulated in rhinitis patients. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | BE0003552 |
| MONCLONAL ANTIBODY | Anti-CX3CR1 for Human |
Record No:192
| ACCESS NO | 100870 |
| GENE | CCL1 |
| DESCRIPTION | Chemokine (C-C motif) ligand 1 |
| NCBI ENTREZ ACCESS NO | 6346 |
| UNIPROT ACCESS NO | P22362 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in activation of T cells. Selected on the basis of fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-I-309 for Human |
Record No:193
| ACCESS NO | 100871 |
| GENE | CCL2 |
| DESCRIPTION | Chemokine (C-C motif) ligand 2 |
| NCBI ENTREZ ACCESS NO | 6347 |
| UNIPROT ACCESS NO | P13500 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Recruits regulatory and effector CD4+ and CD8+ T cells. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | BE0001047 |
| MONCLONAL ANTIBODY | Anti-MCP1 for Mouse/Rat/Human |
Record No:194
| ACCESS NO | 100872 |
| GENE | CCL3 |
| DESCRIPTION | Chemokine (C-C motif) ligand 3 |
| NCBI ENTREZ ACCESS NO | 6348 |
| UNIPROT ACCESS NO | P10147 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | BE0002471 |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 1 alpha for Human |
Record No:195
| ACCESS NO | 100873 |
| GENE | CCL4 |
| DESCRIPTION | Chemokine (C-C motif) ligand 4 |
| NCBI ENTREZ ACCESS NO | 6351 |
| UNIPROT ACCESS NO | P13236 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:196
| ACCESS NO | 100874 |
| GENE | CCL7 |
| DESCRIPTION | Chemokine (C-C motif) ligand 7 |
| NCBI ENTREZ ACCESS NO | 6354 |
| UNIPROT ACCESS NO | P80098 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Associated with the development and activation of T cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MCP3 for Rat/Human |
Record No:197
| ACCESS NO | 100875 |
| GENE | CCL8 |
| DESCRIPTION | Chemokine (C-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 6355 |
| UNIPROT ACCESS NO | P80075 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | BE0002941 |
| MONCLONAL ANTIBODY | Anti-MCP2 for Mouse/Human |
Record No:198
| ACCESS NO | 100876 |
| GENE | CCL11 |
| DESCRIPTION | Chemokine (C-C motif) ligand 11 |
| NCBI ENTREZ ACCESS NO | 6356 |
| UNIPROT ACCESS NO | P51671 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | An important chemokine involved in tissue inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | BE0003389 |
| MONCLONAL ANTIBODY | Anti-Eotaxin for Human |
Record No:199
| ACCESS NO | 100877 |
| GENE | CCL16 |
| DESCRIPTION | Chemokine (C-C motif) ligand 16 |
| NCBI ENTREZ ACCESS NO | 6360 |
| UNIPROT ACCESS NO | O15467 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LEC for Human |
Record No:200
| ACCESS NO | 100878 |
| GENE | CCL17 |
| DESCRIPTION | Chemokine (C-C motif) ligand 17 |
| NCBI ENTREZ ACCESS NO | 6361 |
| UNIPROT ACCESS NO | Q92583 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Associated with the development and activation of T cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:201
| ACCESS NO | 100879 |
| GENE | CX3CL1 |
| DESCRIPTION | Chemokine (C-X3-C motif) ligand 1 |
| NCBI ENTREZ ACCESS NO | 6376 |
| UNIPROT ACCESS NO | P78423 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Expressed on activated endothelial cells and has dual function such as chemoattractant and adhesion. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CX3CL1 for Human |
Record No:202
| ACCESS NO | 100880 |
| GENE | CCL20 |
| DESCRIPTION | Chemokine (C-C motif) ligand 20 |
| NCBI ENTREZ ACCESS NO | 6364 |
| UNIPROT ACCESS NO | P78556 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 3 alpha for Human |
Record No:203
| ACCESS NO | 100881 |
| GENE | CCL22 |
| DESCRIPTION | Chemokine (C-C motif) ligand 22 |
| NCBI ENTREZ ACCESS NO | 6367 |
| UNIPROT ACCESS NO | O00626 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MDC for Human |
Record No:204
| ACCESS NO | 100882 |
| GENE | CCL23 |
| DESCRIPTION | Chemokine (C-C motif) ligand 23 |
| NCBI ENTREZ ACCESS NO | 6368 |
| UNIPROT ACCESS NO | P55773 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 3 for Human |
Record No:205
| ACCESS NO | 100883 |
| GENE | CXCL2 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 2 |
| NCBI ENTREZ ACCESS NO | 2920 |
| UNIPROT ACCESS NO | P19875 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GRO alpha for Human |
Record No:206
| ACCESS NO | 100884 |
| GENE | CXCL3 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 3 |
| NCBI ENTREZ ACCESS NO | 2921 |
| UNIPROT ACCESS NO | P19876 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:207
| ACCESS NO | 100885 |
| GENE | CXCL4 |
| DESCRIPTION | Platelet factor 4 |
| NCBI ENTREZ ACCESS NO | 5196 |
| UNIPROT ACCESS NO | P02776 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | BE0001129 |
| MONCLONAL ANTIBODY | Anti-PF4 for Rat/Human |
Record No:208
| ACCESS NO | 100886 |
| GENE | CXCL5 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 5 |
| NCBI ENTREZ ACCESS NO | 6374 |
| UNIPROT ACCESS NO | P42830 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in rhinitis patients. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CXCL5 for Human |
Record No:209
| ACCESS NO | 100887 |
| GENE | CXCL6 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 6 |
| NCBI ENTREZ ACCESS NO | 6372 |
| UNIPROT ACCESS NO | P80162 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in rhinitis patients. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GCP2 for Human |
Record No:210
| ACCESS NO | 100888 |
| GENE | CXCL11 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 11 |
| NCBI ENTREZ ACCESS NO | 6373 |
| UNIPROT ACCESS NO | O14625 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in rhinitis patients. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CXCL11 for Mouse/Rat/Human |
Record No:211
| ACCESS NO | 100891 |
| GENE | CCR2 |
| DESCRIPTION | Chemokine (C-C motif) receptor 2 |
| NCBI ENTREZ ACCESS NO | 729230 |
| UNIPROT ACCESS NO | P41597 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in rhinitis patients. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | BE0003387 |
| MONCLONAL ANTIBODY | Anti-CCR2 for Mouse/Rat/Humna |
Record No:212
| ACCESS NO | 100892 |
| GENE | CCR3 |
| DESCRIPTION | chemokine (C-C motif) receptor 3 |
| NCBI ENTREZ ACCESS NO | 1232 |
| UNIPROT ACCESS NO | P51677 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in rhinitis patients. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CCR3 for Rat/Mouse/Human |
Record No:213
| ACCESS NO | 100893 |
| GENE | CCR5 |
| DESCRIPTION | Chemokine (C-C motif) receptor 5 |
| NCBI ENTREZ ACCESS NO | 1234 |
| UNIPROT ACCESS NO | P51681 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Helps Th1 cells to move to site of inflammation.Upregulated in rhinitis patients. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | BE0000911 |
| MONCLONAL ANTIBODY | Anti-CCR5 for Mouse/Rat/Human |
Record No:214
| ACCESS NO | 100894 |
| GENE | CCR6 |
| DESCRIPTION | Chemokine (C-C motif) receptor 6 |
| NCBI ENTREZ ACCESS NO | 1235 |
| UNIPROT ACCESS NO | P51684 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in rhinitis patients. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CCR6 for Human |
Record No:215
| ACCESS NO | 100895 |
| GENE | CCR7 |
| DESCRIPTION | Chemokine (C-C motif) receptor 7 |
| NCBI ENTREZ ACCESS NO | 1236 |
| UNIPROT ACCESS NO | P32248 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in rhinitis patients. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17982926 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CCR7 for Mouse/Rat/Human |
Record No:216
| ACCESS NO | 100900 |
| GENE | C1QR1 |
| DESCRIPTION | CD93 molecule |
| NCBI ENTREZ ACCESS NO | 22918 |
| UNIPROT ACCESS NO | Q9NPY3 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic sensitization to pollen allergens |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Illumina microarray chips and Genome wide associat |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in T cell activation. Downregulated in this study. |
| GEO_PRIDE_ACCESS_NO | GSE18574 |
| REFERENCE | 24116013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD93 for Mouse/Rat/Human |
Record No:217
| ACCESS NO | 100901 |
| GENE | CFD |
| DESCRIPTION | Complement factor D |
| NCBI ENTREZ ACCESS NO | 1675 |
| UNIPROT ACCESS NO | P00746 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic sensitization to pollen allergens |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Illumina microarray chips and Genome wide associat |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Shifts T cell differentiation towards IFNG secreting effector T cells by allowing complement activation during APC/T cell interactions. |
| GEO_PRIDE_ACCESS_NO | GSE18575 |
| REFERENCE | 24116013 |
| DRUG TARGET | BE0001840 |
| MONCLONAL ANTIBODY | Anti-Factor D for Human |
Record No:218
| ACCESS NO | 100902 |
| GENE | CFP |
| DESCRIPTION | Complement factor properdin |
| NCBI ENTREZ ACCESS NO | 5199 |
| UNIPROT ACCESS NO | P27918 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic sensitization to pollen allergens |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Illumina microarray chips and Genome wide associat |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Controls activation of complement systems and secreted by peripheral blood T cells. Downregulated in this study. |
| GEO_PRIDE_ACCESS_NO | GSE18576 |
| REFERENCE | 24116013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Properdin for Human |
Record No:219
| ACCESS NO | 100905 |
| GENE | C3AR1 |
| DESCRIPTION | Complement component 3a receptor 1 |
| NCBI ENTREZ ACCESS NO | 719 |
| UNIPROT ACCESS NO | Q16581 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic sensitization to pollen allergens |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Illumina microarray chips and Genome wide associat |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Significantly associated with allergic sensitisation in GWAS data.Downregulated in allergic patients. |
| GEO_PRIDE_ACCESS_NO | GSE18579 |
| REFERENCE | 24116013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-C3a Receptor for Rat/Human |
Record No:220
| ACCESS NO | 100906 |
| GENE | C5AR1 |
| DESCRIPTION | Complement component 5a receptor 1 |
| NCBI ENTREZ ACCESS NO | 728 |
| UNIPROT ACCESS NO | P21730 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic sensitization to pollen allergens |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Illumina microarray chips and Genome wide associat |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in the complement system pathway. Downregulated in allergic patients. |
| GEO_PRIDE_ACCESS_NO | GSE18580 |
| REFERENCE | 24116013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-C5R1 for Rabbit/Human |
Record No:221
| ACCESS NO | 100909 |
| GENE | CD81 |
| DESCRIPTION | CD81 molecule |
| NCBI ENTREZ ACCESS NO | 975 |
| UNIPROT ACCESS NO | P60033 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic sensitization to pollen allergens |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Illumina microarray chips and Genome wide associat |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Increased expression is involved in Tcell differentiation. |
| GEO_PRIDE_ACCESS_NO | GSE18583 |
| REFERENCE | 24116013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TAPA1 for Mouse/Rat/Human |
Record No:222
| ACCESS NO | 100912 |
| GENE | C3 |
| DESCRIPTION | Complement component 3 |
| NCBI ENTREZ ACCESS NO | 12266 |
| UNIPROT ACCESS NO | P01027 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Helps in the induction of Th2 response and plays a pivotal role as mediator of airway hyperresponsiveness. Upregulated in all three food allergen sensitization. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | BE0003455 |
| MONCLONAL ANTIBODY | Anti-C3 for Rat/Mouse |
Record No:223
| ACCESS NO | 100923 |
| GENE | Cd79a |
| DESCRIPTION | CD79A antigen |
| NCBI ENTREZ ACCESS NO | 12518 |
| UNIPROT ACCESS NO | P11911 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Downregulated in beta lactoglobulin sensitization. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD79a for Mouse/Rat/Human |
Record No:224
| ACCESS NO | 100938 |
| GENE | Car4 |
| DESCRIPTION | Carbonic anhydrase 4 |
| NCBI ENTREZ ACCESS NO | 12351 |
| UNIPROT ACCESS NO | Q64444 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after induction with food allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:225
| ACCESS NO | 100940 |
| GENE | Car2 |
| DESCRIPTION | Carbonic anhydrase 2 |
| NCBI ENTREZ ACCESS NO | 12349 |
| UNIPROT ACCESS NO | P00920 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after induction with food allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Carbonic Anhydrase II for Rat/Mouse/Human |
Record No:226
| ACCESS NO | 100944 |
| GENE | Car1 |
| DESCRIPTION | Carbonic anhydrase 1 |
| NCBI ENTREZ ACCESS NO | 12346 |
| UNIPROT ACCESS NO | P13634 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after induction with food allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Carbonic Anhydrase I for Mouse/Rat/Human |
Record No:227
| ACCESS NO | 100950 |
| GENE | CD69 |
| DESCRIPTION | CD69 |
| NCBI ENTREZ ACCESS NO | 969 |
| UNIPROT ACCESS NO | Q07108 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Eosinophils from Peripheral blood |
| TECHNIQUES | Western blotting Flow cytometry ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | A marker of cell activation and expressed and upregulated after IL7 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19155487 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD69 for Mouse/Human |
Record No:228
| ACCESS NO | 100954 |
| GENE | CTLA4 |
| DESCRIPTION | Cytotoxic T-lymphocyte-associated protein 4 |
| NCBI ENTREZ ACCESS NO | 1493 |
| UNIPROT ACCESS NO | P16410 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Genomic DNA from buccal cells |
| TECHNIQUES | Illumina HumanHap 550 k BeadChip version 4 |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Identified as potential susceptibility gene for allergic rhinitis. May be a genetic link between asthma and allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23663310 |
| DRUG TARGET | BE0000887 |
| MONCLONAL ANTIBODY | Anti-CTLA4 for Mouse/Rat/Human |
Record No:229
| ACCESS NO | 100955 |
| GENE | CXCR3 |
| DESCRIPTION | Chemokine (C-X-C motif) receptor 3 |
| NCBI ENTREZ ACCESS NO | 2833 |
| UNIPROT ACCESS NO | P49682 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in Obese patients |
| SAMPLE | Peripheral Blood mononuclear cells |
| TECHNIQUES | Flow cytometry and immunoflorescent staining |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Regulates the migration of Th1 cells into sites of Th1-driven inflammation and is a major inflammatory molecule in obese patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23760409 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | Anti-CXCR3 for Mouse/Human |
Record No:230
| ACCESS NO | 100959 |
| GENE | CCR5 |
| DESCRIPTION | Chemokine (C-C motif) receptor 5 |
| NCBI ENTREZ ACCESS NO | 1234 |
| UNIPROT ACCESS NO | P51681 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in Obese patients |
| SAMPLE | Peripheral Blood mononuclear cells |
| TECHNIQUES | Flow cytometry and immunoflorescent staining |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Overexpressed in obese asthma patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23760409 |
| DRUG TARGET | BE0000911 |
| MONCLONAL ANTIBODY | Anti-CCR5 for Mouse/Rat/Human |
Record No:231
| ACCESS NO | 100987 |
| GENE | CCL24 |
| DESCRIPTION | Eotaxin-2 |
| NCBI ENTREZ ACCESS NO | 6369 |
| UNIPROT ACCESS NO | O00175 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Occupational asthma |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | Meso Scale Discovery Assays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokine is significantly induced by HClPt with up to 203%. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Eotaxin 2 for Human |
Record No:232
| ACCESS NO | 100988 |
| GENE | CCL11 |
| DESCRIPTION | Eotaxin |
| NCBI ENTREZ ACCESS NO | 6356 |
| UNIPROT ACCESS NO | P51671 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0003389 |
| MONCLONAL ANTIBODY | Anti-Eotaxin for Human |
Record No:233
| ACCESS NO | 100989 |
| GENE | CCL5 (RANTES) |
| DESCRIPTION | Chemokine (C-C motif) ligand 5 |
| NCBI ENTREZ ACCESS NO | 6352 |
| UNIPROT ACCESS NO | P13501 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0000975 |
| MONCLONAL ANTIBODY | Anti-RANTES for Human |
Record No:234
| ACCESS NO | 100992 |
| GENE | CCL4 (MIP-1b) |
| DESCRIPTION | Chemokine (C-C motif) ligand 4 |
| NCBI ENTREZ ACCESS NO | 6351 |
| UNIPROT ACCESS NO | P13236 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:235
| ACCESS NO | 100994 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:236
| ACCESS NO | 100996 |
| GENE | CCL2 (MCP-1) |
| DESCRIPTION | Chemokine (C-C motif) ligand 2 |
| NCBI ENTREZ ACCESS NO | 6347 |
| UNIPROT ACCESS NO | P13500 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0001047 |
| MONCLONAL ANTIBODY | N/A |
Record No:237
| ACCESS NO | 100997 |
| GENE | CXCL10 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 10 |
| NCBI ENTREZ ACCESS NO | 3627 |
| UNIPROT ACCESS NO | P02778 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | Anti-IP10 for Human |
Record No:238
| ACCESS NO | 101001 |
| GENE | CCR7 |
| DESCRIPTION | Chemokine (C-C motif) receptor 7 |
| NCBI ENTREZ ACCESS NO | 1236 |
| UNIPROT ACCESS NO | P32248 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows highest expression in patients with eosinophilic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CCR7 for Mouse/Human/Rat |
Record No:239
| ACCESS NO | 101002 |
| GENE | CEBPE |
| DESCRIPTION | CCAAT/enhancer binding protein (C/EBP) - epsilon |
| NCBI ENTREZ ACCESS NO | 1053 |
| UNIPROT ACCESS NO | Q15744 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows highest expression in patients with eosinophilic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CEBPE [EPR12097] for Human |
Record No:240
| ACCESS NO | 101003 |
| GENE | CLC |
| DESCRIPTION | Charcot-Leydon crystal protein (Galectin-10) |
| NCBI ENTREZ ACCESS NO | 1178 |
| UNIPROT ACCESS NO | Q05315 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows highest expression in patients with eosinophilic asthma. Its expression decresed after inhaled corticosteroid treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | BE0001886 |
| MONCLONAL ANTIBODY | N/A |
Record No:241
| ACCESS NO | 101004 |
| GENE | CPA3 |
| DESCRIPTION | Carboxypeptidase A3 |
| NCBI ENTREZ ACCESS NO | 1359 |
| UNIPROT ACCESS NO | P15088 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows highest expression in patients with eosinophilic asthma. Its expression decresed after inhaled corticosteroid treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:242
| ACCESS NO | 101005 |
| GENE | CXCR1 |
| DESCRIPTION | Chemokine (C-X-C motif) receptor 1 |
| NCBI ENTREZ ACCESS NO | 3577 |
| UNIPROT ACCESS NO | P25024 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows highest expression in patients with neutrophilic asthma. Corticosteroids are known to increase the expression of this gene. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | BE0003552 |
| MONCLONAL ANTIBODY | Anti-CXCR1 for Human/Rat |
Record No:243
| ACCESS NO | 101006 |
| GENE | CXCR2 |
| DESCRIPTION | Chemokine (C-X-C motif) receptor 2 |
| NCBI ENTREZ ACCESS NO | 3579 |
| UNIPROT ACCESS NO | P25025 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows highest expression in patients with neutrophilic asthma. Corticosteroids are known to increase the expression of this gene. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CXCR2 for Human |
Record No:244
| ACCESS NO | 101038 |
| GENE | CTSD |
| DESCRIPTION | Cathepsin D |
| NCBI ENTREZ ACCESS NO | 1509 |
| UNIPROT ACCESS NO | P07339 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly upregulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | BE0000941 |
| MONCLONAL ANTIBODY | Anti-Cathepsin D for Mouse/Human |
Record No:245
| ACCESS NO | 101041 |
| GENE | CALML5 |
| DESCRIPTION | Calmodulin-like protein 5 |
| NCBI ENTREZ ACCESS NO | 51806 |
| UNIPROT ACCESS NO | Q9NZT1 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This is a calcium-binding protein and a marker for late keratinocyte differentiation. Its ability to associate with transglutaminase-3 indicates an important role of this protein in the epidermal barrier function. This protein is strongly down regulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:246
| ACCESS NO | 101043 |
| GENE | CD59 |
| DESCRIPTION | CD59 glycoprotein |
| NCBI ENTREZ ACCESS NO | 966 |
| UNIPROT ACCESS NO | P13987 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly down regulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD59 for Mouse/Human |
Record No:247
| ACCESS NO | 101051 |
| GENE | CTSH |
| DESCRIPTION | Pro-cathepsin H |
| NCBI ENTREZ ACCESS NO | 1512 |
| UNIPROT ACCESS NO | P09668 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly down regulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | BE0003970 |
| MONCLONAL ANTIBODY | Anti-Cathepsin H for Rat/Human |
Record No:248
| ACCESS NO | 101058 |
| GENE | C3a |
| DESCRIPTION | chain A human complement component C3 |
| NCBI ENTREZ ACCESS NO | 718 |
| UNIPROT ACCESS NO | P01024 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and aspirin tolerance |
| SAMPLE | Plasma |
| TECHNIQUES | 2DE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Expression of this protein is increased in Aspirin-exacerbated respiratory disease (AERD) as compared to aspirin-tolerant asthma (ATA). |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24120690 |
| DRUG TARGET | BE0003455 |
| MONCLONAL ANTIBODY | Anti-C3a / C3a des Arg for Human |
Record No:249
| ACCESS NO | 101059 |
| GENE | C4A |
| DESCRIPTION | complement component C4a |
| NCBI ENTREZ ACCESS NO | 720 |
| UNIPROT ACCESS NO | P0C0L4 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and aspirin tolerance |
| SAMPLE | Plasma |
| TECHNIQUES | 2DE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Expression of this protein is increased in Aspirin-exacerbated respiratory disease (AERD) as compared to aspirin-tolerant asthma (ATA). |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24120690 |
| DRUG TARGET | BE0004685 |
| MONCLONAL ANTIBODY | Anti-C4a [EPR10143] for Human |
Record No:250
| ACCESS NO | 101061 |
| GENE | CRP |
| DESCRIPTION | C-Reactive Protein |
| NCBI ENTREZ ACCESS NO | 1401 |
| UNIPROT ACCESS NO | P02741 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | is one of the most characteristic surrogate markers of systemic inflammation. Significantly higher plasma CRP levels was found at acute exacerbation and remained elevated during remission compared with healthy controls. This reflects chronic systemic inflammation in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24073339 |
| DRUG TARGET | BE0000877 |
| MONCLONAL ANTIBODY | Anti-C Reactive Protein for Human |
Record No:251
| ACCESS NO | 101064 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Interleukin 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Saliva |
| TECHNIQUES | Fiber-optic bundles and antibody-based microarrays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This saliva biomarker was found to be upregulated significantly in asthma patients as compared to control. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23972398 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:252
| ACCESS NO | 101067 |
| GENE | CRP |
| DESCRIPTION | C-Reactive Protein |
| NCBI ENTREZ ACCESS NO | 1401 |
| UNIPROT ACCESS NO | P02741 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | BE0000877 |
| MONCLONAL ANTIBODY | Anti-C Reactive Protein for Human |
Record No:253
| ACCESS NO | 101069 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Interleukin 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:254
| ACCESS NO | 101074 |
| GENE | CHI3L1 (YKL-40) |
| DESCRIPTION | Chitinase 3-like 1 |
| NCBI ENTREZ ACCESS NO | 1116 |
| UNIPROT ACCESS NO | P36222 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:255
| ACCESS NO | 101075 |
| GENE | CD86 |
| DESCRIPTION | soluble CD86 |
| NCBI ENTREZ ACCESS NO | 942 |
| UNIPROT ACCESS NO | P42081 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | BE0000846 |
| MONCLONAL ANTIBODY | Anti-CD86 [EP1158Y] for Rat/Human |
Record No:256
| ACCESS NO | 101078 |
| GENE | CLCA1 |
| DESCRIPTION | Calcium activated chloride channel family member 1 |
| NCBI ENTREZ ACCESS NO | 1179 |
| UNIPROT ACCESS NO | A8K7I4 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Airway epithelial brushings |
| TECHNIQUES | qPCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This three-gene-mean study will help to optimize the threshold for serum periostin that best identifies individuals that will respond to inhaled cortico steroid or Th2-targeted therapies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23866775 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CLCA1 [EPR12254-88] for Mouse/Rat/Human |
Record No:257
| ACCESS NO | 101094 |
| GENE | CHI3L1 (YKL-40) |
| DESCRIPTION | Chitinase 3-like 1 |
| NCBI ENTREZ ACCESS NO | 1116 |
| UNIPROT ACCESS NO | P36222 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | ELISA and SNP typing of the gene promoter |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | YKL-40 levels are increased in children with severe and therapy-resistant asthma compared to healthy children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23628340 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:258
| ACCESS NO | 101097 |
| GENE | CXCL10 (IP-10) |
| DESCRIPTION | Inducible protein-10 |
| NCBI ENTREZ ACCESS NO | 3627 |
| UNIPROT ACCESS NO | P02778 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Exhaled breath condensate |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is a biomarker of exacerbation. This chemokine is strongly associated with viral infection in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23521049 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | N/A |
Record No:259
| ACCESS NO | 101101 |
| GENE | CCL26 (eotaxin-3) |
| DESCRIPTION | chemokine (C-C motif) ligand 26 |
| NCBI ENTREZ ACCESS NO | 10344 |
| UNIPROT ACCESS NO | Q9Y258 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasal epithelial cells |
| TECHNIQUES | real-time RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This gene was found to be significantly elevated in samples from asthmatic donors suggesting nasal CCL26 has potential as a reliable epithelial biomarker that correlates with allergic bronchial asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23402658 |
| DRUG TARGET | BE0003389 |
| MONCLONAL ANTIBODY | Anti-Eotaxin 3 for Human |
Record No:260
| ACCESS NO | 101127 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Pediatric asthma and Polycyclic aromatic hydrocarbon exposure |
| SAMPLE | Fasting blood |
| TECHNIQUES | Multiplex immunoassay using Luminex 100 system pla |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Exposure to polycyclic hydrocarbon has strong association with decrease in serum concentration of this biomarker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23286340 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:261
| ACCESS NO | 101133 |
| GENE | CCL22 |
| DESCRIPTION | Chemokine (C-C motif) ligand 22 |
| NCBI ENTREZ ACCESS NO | 6367 |
| UNIPROT ACCESS NO | O00626 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Cord blood |
| TECHNIQUES | Multiplexed Luminex assay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | High cord blood levels of the Th2 related chemokine CCL22 were significantly associated with high total- IgE levels during the first 6Â years of life. This suggests an inborn Th2 skewing of the immune system in healthy newborns developing elevated total-IgE later in life. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23106659 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:262
| ACCESS NO | 101134 |
| GENE | CCL17 |
| DESCRIPTION | chemokine (C-C motif) ligand 17 |
| NCBI ENTREZ ACCESS NO | 6361 |
| UNIPROT ACCESS NO | Q92583 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Monocytes derived macrophage |
| TECHNIQUES | Flow cytometry and Real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Lung macrophages of asthmatic patients express more CCL17. It is associated with sputum eosinophilia and cannot be suppressed by corticosteroids but can be attenuated by PI3Kinase inhibition. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22981793 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:263
| ACCESS NO | 101135 |
| GENE | CD163 |
| DESCRIPTION | CD163 molecule |
| NCBI ENTREZ ACCESS NO | 9332 |
| UNIPROT ACCESS NO | Q86VB7 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Monocytes derived macrophage |
| TECHNIQUES | Flow cytometry and Real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Less CD163 was found in Lung macrophages of asthmatic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22981793 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD163 for Human |
Record No:264
| ACCESS NO | 101144 |
| GENE | CCL2 (MCP-1) |
| DESCRIPTION | Monocyte chemoattractant protein-1 |
| NCBI ENTREZ ACCESS NO | 6347 |
| UNIPROT ACCESS NO | P13500 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Higher levels of this biomarker is associated with male sex. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0001047 |
| MONCLONAL ANTIBODY | N/A |
Record No:265
| ACCESS NO | 101149 |
| GENE | CSF3 (G-CSF) |
| DESCRIPTION | Granulocyte macrophage colony-stimulating factor |
| NCBI ENTREZ ACCESS NO | 1440 |
| UNIPROT ACCESS NO | P09919 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This gene is involved in neovascularization/remodulation after tissue damage. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0000793 |
| MONCLONAL ANTIBODY | Anti-G-CSF for Human |
Record No:266
| ACCESS NO | 101151 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | strong chemotactic effect on neutrophils |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:267
| ACCESS NO | 101154 |
| GENE | CCL3 (MIP-1α) |
| DESCRIPTION | Macrophage inflammatory protein-1 alpha |
| NCBI ENTREZ ACCESS NO | 6348 |
| UNIPROT ACCESS NO | P10147 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This gene is involved in innate immune response. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0002471 |
| MONCLONAL ANTIBODY | N/A |
Record No:268
| ACCESS NO | 101156 |
| GENE | CCL11 |
| DESCRIPTION | Eotaxin |
| NCBI ENTREZ ACCESS NO | 6356 |
| UNIPROT ACCESS NO | P51671 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This gene is involved in neovascularization/remodulation after tissue damage. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0003389 |
| MONCLONAL ANTIBODY | Anti-Eotaxin for Human |
Record No:269
| ACCESS NO | 101158 |
| GENE | CCL5 (RANTES) |
| DESCRIPTION | Chemokine (C-C motif) ligand 5 |
| NCBI ENTREZ ACCESS NO | 6352 |
| UNIPROT ACCESS NO | P13501 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This gene is involved in neovascularization/remodulation after tissue damage. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0000975 |
| MONCLONAL ANTIBODY | Anti-RANTES for Human |
Record No:270
| ACCESS NO | 101160 |
| GENE | CLIC2 |
| DESCRIPTION | Chloride intracellular channel 2 |
| NCBI ENTREZ ACCESS NO | 1193 |
| UNIPROT ACCESS NO | O15247 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
| SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
| TECHNIQUES | 2D-DIGE and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is a regulatory marker of dendritic cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22464673 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CLIC2 for Human |
Record No:271
| ACCESS NO | 101166 |
| GENE | C1QA |
| DESCRIPTION | Complement component 1 - q subcomponent - A chain |
| NCBI ENTREZ ACCESS NO | 712 |
| UNIPROT ACCESS NO | P02745 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
| SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
| TECHNIQUES | Label free nano-LC-MS/MS and western blot and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is regulated in PBMCs from patients in the active immunotherapy group when compared with the placebo group. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22464673 |
| DRUG TARGET | BE0002094 |
| MONCLONAL ANTIBODY | Anti-C1QA for Human |
Record No:272
| ACCESS NO | 101167 |
| GENE | C1QB |
| DESCRIPTION | Complement component 1 - q subcomponent - b chain |
| NCBI ENTREZ ACCESS NO | 713 |
| UNIPROT ACCESS NO | P02746 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
| SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
| TECHNIQUES | Label free nano-LC-MS/MS and western blot and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is regulated in PBMCs from patients in the active immunotherapy group when compared with the placebo group. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22464673 |
| DRUG TARGET | BE0002095 |
| MONCLONAL ANTIBODY | Anti-C1QB for Human |
Record No:273
| ACCESS NO | 101168 |
| GENE | C1QC |
| DESCRIPTION | Complement component 1 - q subcomponent - c chain |
| NCBI ENTREZ ACCESS NO | 714 |
| UNIPROT ACCESS NO | P02747 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
| SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
| TECHNIQUES | Label free nano-LC-MS/MS and western blot and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is overexpressed in various types of tolerogenic dendritic cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22464673 |
| DRUG TARGET | BE0002096 |
| MONCLONAL ANTIBODY | Anti-C1QC for Human |
Record No:274
| ACCESS NO | 101169 |
| GENE | CTSC (CATC) |
| DESCRIPTION | Cathepsin C |
| NCBI ENTREZ ACCESS NO | 1075 |
| UNIPROT ACCESS NO | P53634 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
| SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
| TECHNIQUES | Label free nano-LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is overexpressed in various types of tolerogenic dendritic cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22464673 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:275
| ACCESS NO | 101174 |
| GENE | C15orf48 (NMES1) |
| DESCRIPTION | Normal mucosa of esophagus specific 1 |
| NCBI ENTREZ ACCESS NO | 84419 |
| UNIPROT ACCESS NO | Q9C002 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
| SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
| TECHNIQUES | Label free nano-LC-MS/MS and western blot |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is a marker of effector dendritic cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22464673 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:276
| ACCESS NO | 101177 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of polychlorinated biphenyls (PCB) |
| SAMPLE | Blood |
| TECHNIQUES | qPCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Serum concentrations of PCB correlate significantly with IL-8 mRNA expressions among asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22326254 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:277
| ACCESS NO | 101193 |
| GENE | CRP |
| DESCRIPTION | C-Reactive Protein |
| NCBI ENTREZ ACCESS NO | 1401 |
| UNIPROT ACCESS NO | P02741 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and obesity |
| SAMPLE | Serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | The higher CRP levels was correlated with severe asthma. CRP concentrations reduced after 1 year of interdisciplinary treatment from 2073 to 1. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22170805 |
| DRUG TARGET | BEE0000877 |
| MONCLONAL ANTIBODY | Anti-C Reactive Protein for Human |
Record No:278
| ACCESS NO | 101198 |
| GENE | CRABP2 |
| DESCRIPTION | Cellular retinoic acid-binding protein 2 |
| NCBI ENTREZ ACCESS NO | 1382 |
| UNIPROT ACCESS NO | P29373 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | BE0000782 |
| MONCLONAL ANTIBODY | Anti-CRABP2 [EPR14256(B)] for Human |
Record No:279
| ACCESS NO | 101199 |
| GENE | CSGALNACT1 |
| DESCRIPTION | Chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| NCBI ENTREZ ACCESS NO | 55790 |
| UNIPROT ACCESS NO | Q8TDX6 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:280
| ACCESS NO | 101200 |
| GENE | C2 |
| DESCRIPTION | Complement C2 |
| NCBI ENTREZ ACCESS NO | 717 |
| UNIPROT ACCESS NO | P06681 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:281
| ACCESS NO | 101201 |
| GENE | CD207 |
| DESCRIPTION | C-type lectin domain family 4 member K |
| NCBI ENTREZ ACCESS NO | 50489 |
| UNIPROT ACCESS NO | Q9UJ71 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Langerin [12D6] for Human |
Record No:282
| ACCESS NO | 101216 |
| GENE | CDC73 |
| DESCRIPTION | Parafibromin |
| NCBI ENTREZ ACCESS NO | 79577 |
| UNIPROT ACCESS NO | Q6P1J9 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HRPT2 for Mouse/Rat/Human |
Record No:283
| ACCESS NO | 101225 |
| GENE | C5orf30 |
| DESCRIPTION | UPF0684 protein C5orf30 |
| NCBI ENTREZ ACCESS NO | 90355 |
| UNIPROT ACCESS NO | Q96GV9 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:284
| ACCESS NO | 101227 |
| GENE | C3 |
| DESCRIPTION | Complement component C3 |
| NCBI ENTREZ ACCESS NO | 718 |
| UNIPROT ACCESS NO | P01024 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | Immunodiffusion assay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increase in the serum levels of the C3 components of the complement system in the majority of the patients with intermittent atopic asthma was observed. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22065014 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:285
| ACCESS NO | 101228 |
| GENE | C4 |
| DESCRIPTION | Complement component C4 |
| NCBI ENTREZ ACCESS NO | 720 |
| UNIPROT ACCESS NO | P0C0L4 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | Immunodiffusion assay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increase in the serum levels of the C4 components of the complement system in the majority of the patients with intermittent atopic asthma was observed. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22065014 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:286
| ACCESS NO | 101231 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Skin allergy induced by formaldehyde |
| SAMPLE | THP-1 cell line |
| TECHNIQUES | qPCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This inflammatory marker is upregulated in a time depenent manner upon bronopol as well as formaldehyde and dimethylol - dimethylhydantoin challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22034943 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL1B for Human |
Record No:287
| ACCESS NO | 101236 |
| GENE | CXCL10 (IP-10) |
| DESCRIPTION | Inducible protein-10 |
| NCBI ENTREZ ACCESS NO | 3627 |
| UNIPROT ACCESS NO | P02778 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma and obesity related asthma |
| SAMPLE | Fasting serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This is a Th1 specific biomarker can distinguish obesity asthma from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21980061 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | N/A |
Record No:288
| ACCESS NO | 101240 |
| GENE | CCL16 |
| DESCRIPTION | Chemokine (C-C motif) ligand 16 |
| NCBI ENTREZ ACCESS NO | 6360 |
| UNIPROT ACCESS NO | O15467 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Respiratory allergy and effect of wood fuel |
| SAMPLE | Serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Small changes in serum CCL16 level reveal the existence of early subclinical effects in the airways epithelium and it is most likely caused by irritating agents in wood smoke. A decrease of CC16 and an increase of the CC16 over SPD ratio in serum can be explained by a decreased production of CC16. CCL16 is a major protein in the lung with anti-inflammatory activity and the increased lung permeability. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21901861 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LEC for Human |
Record No:289
| ACCESS NO | 101241 |
| GENE | CHI3L1 (YKL-40) |
| DESCRIPTION | Chitinase 3-like 1 |
| NCBI ENTREZ ACCESS NO | 1116 |
| UNIPROT ACCESS NO | P36222 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | YKL-40 seems to be a good marker of asthma.But its level may not correlate with clinical outcome. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21899483 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:290
| ACCESS NO | 101252 |
| GENE | Chia1 (Chia) |
| DESCRIPTION | Amcase |
| NCBI ENTREZ ACCESS NO | 81600 |
| UNIPROT ACCESS NO | Q91XA9 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
| SAMPLE | Lung tissue |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Pretreatment with artesunate (30 mg/kg) demonstrated strong suppression of this chitinase essential for airway inflammation and remodeling. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | BE0001649 |
| MONCLONAL ANTIBODY | N/A |
Record No:291
| ACCESS NO | 101253 |
| GENE | Chi3l4 (Ym-2) |
| DESCRIPTION | Chitinase 3-like protein 4 |
| NCBI ENTREZ ACCESS NO | 104183 |
| UNIPROT ACCESS NO | Q91Z98 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
| SAMPLE | Lung tissue |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Pretreatment with artesunate (30 mg/kg) demonstrated strong suppression of this chitinase essential for airway inflammation and remodeling. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:292
| ACCESS NO | 101254 |
| GENE | CHI3L1 (YKL-40) |
| DESCRIPTION | Chitinase-3-like protein 1 |
| NCBI ENTREZ ACCESS NO | 12654 |
| UNIPROT ACCESS NO | Q61362 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
| SAMPLE | Lung tissue |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Pretreatment with artesunate (30 mg/kg) demonstrated strong suppression of this chitinase essential for airway inflammation and remodeling. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:293
| ACCESS NO | 101265 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe and mild asthma |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This study suggests that there is not any difference between severe and mild asthma in serum IL-8 and IL-6. Thus level of serum cytokines may not predict severity of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24024021 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:294
| ACCESS NO | 101319 |
| GENE | CCT8 |
| DESCRIPTION | Chaperonin containing TCP1 subunit 8 (CCT) |
| NCBI ENTREZ ACCESS NO | 10694 |
| UNIPROT ACCESS NO | P50990 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy(Comparison of Dendritic cell proteome in atopic and non atopic patients) |
| SAMPLE | Dendritic cell |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in ATP binding and protein folding. Differentially expressed both in atopic and non atopic patients after Der P1 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19494521 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:295
| ACCESS NO | 101321 |
| GENE | CSK |
| DESCRIPTION | c-src tyrosine kinase |
| NCBI ENTREZ ACCESS NO | 1445 |
| UNIPROT ACCESS NO | P41240 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy(Comparison of Dendritic cell proteome in atopic and non atopic patients) |
| SAMPLE | Dendritic cell |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in intracellular signalling cascade.Differentially expressed in atopic individuals after administering active and inactive Der P1. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19494521 |
| DRUG TARGET | BE0001356 |
| MONCLONAL ANTIBODY | Anti-CSK for Mouse/Rat/Human |
Record No:296
| ACCESS NO | 101322 |
| GENE | CTSB |
| DESCRIPTION | Cathepsin B |
| NCBI ENTREZ ACCESS NO | 1508 |
| UNIPROT ACCESS NO | P07858 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy(Comparison of Dendritic cell proteome in atopic and non atopic patients) |
| SAMPLE | Dendritic cell |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in proteolysis and peptidolysis. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19494521 |
| DRUG TARGET | BE0000939 |
| MONCLONAL ANTIBODY | Anti-Cathepsin B for Human |
Record No:297
| ACCESS NO | 101323 |
| GENE | CTSD |
| DESCRIPTION | Cathepsin D |
| NCBI ENTREZ ACCESS NO | 1509 |
| UNIPROT ACCESS NO | P07339 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy(Comparison of Dendritic cell proteome in atopic and non atopic patients) |
| SAMPLE | Dendritic cell |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Differentially expressed after Der P1 induction in both atopic and non atopic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19494521 |
| DRUG TARGET | BE0000941 |
| MONCLONAL ANTIBODY | Anti-Cathepsin D for Mouse/Human |
Record No:298
| ACCESS NO | 101328 |
| GENE | CLIC1 |
| DESCRIPTION | Chloride intracellular channel 1 |
| NCBI ENTREZ ACCESS NO | 1192 |
| UNIPROT ACCESS NO | O00299 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy(Comparison of Dendritic cell proteome in atopic and non atopic patients) |
| SAMPLE | Dendritic cell |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in signal transduction and transport. Differentially expressed in non atopic individuals after administering active and inactive Der P1. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19494521 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CLIC1 for Human |
Record No:299
| ACCESS NO | 101331 |
| GENE | CMA1 |
| DESCRIPTION | Chymase |
| NCBI ENTREZ ACCESS NO | 1215 |
| UNIPROT ACCESS NO | P23946 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic airway disease |
| SAMPLE | Nasal Lavage |
| TECHNIQUES | Western blot |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | A protease by nature and produced by degranulation of mast cells. Increased in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19400896 |
| DRUG TARGET | BE0001038 |
| MONCLONAL ANTIBODY | Anti-Mast Cell Chymase for Human/Pig |
Record No:300
| ACCESS NO | 101350 |
| GENE | CRP |
| DESCRIPTION | C reactive protein |
| NCBI ENTREZ ACCESS NO | 1401 |
| UNIPROT ACCESS NO | P02741 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Higher in asthma compared in control. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18513240 |
| DRUG TARGET | BE0000877 |
| MONCLONAL ANTIBODY | Anti-C Reactive Protein for Human |
Record No:301
| ACCESS NO | 101354 |
| GENE | Capzb |
| DESCRIPTION | Capping protein |
| NCBI ENTREZ ACCESS NO | 12345 |
| UNIPROT ACCESS NO | P47757 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in cell migration and adhesion. Significantly upregulated by 2 fold. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CAPZB Mouse/ Rat/ Human |
Record No:302
| ACCESS NO | 101359 |
| GENE | Chil4 |
| DESCRIPTION | Ym2 |
| NCBI ENTREZ ACCESS NO | 104183 |
| UNIPROT ACCESS NO | Q91Z98 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Plays a key role in effector immune cell recruitment and airway remodelling. Upregulated in asthmatic mouse. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:303
| ACCESS NO | 101361 |
| GENE | Chia1 |
| DESCRIPTION | Acidic mammalian chitinase |
| NCBI ENTREZ ACCESS NO | 81600 |
| UNIPROT ACCESS NO | Q91XA9 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in mouse Chronic lung inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | BE0003135 |
| MONCLONAL ANTIBODY | N/A |
Record No:304
| ACCESS NO | 101363 |
| GENE | Cxcl15 |
| DESCRIPTION | Lungkine |
| NCBI ENTREZ ACCESS NO | 20309 |
| UNIPROT ACCESS NO | Q9WVL7 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Expressed in Chronic asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CXCL15 for Mouse |
Record No:305
| ACCESS NO | 101364 |
| GENE | Cfb |
| DESCRIPTION | Properdin factor B |
| NCBI ENTREZ ACCESS NO | 14962 |
| UNIPROT ACCESS NO | P04186 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Expressed in Chronic asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:306
| ACCESS NO | 101373 |
| GENE | Ces1d |
| DESCRIPTION | Carboxylesterase 3 |
| NCBI ENTREZ ACCESS NO | 104158 |
| UNIPROT ACCESS NO | Q8VCT4 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in chronic asthma mouse model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:307
| ACCESS NO | 101385 |
| GENE | Col6a1 |
| DESCRIPTION | Procollagen type VI a1 |
| NCBI ENTREZ ACCESS NO | 12833 |
| UNIPROT ACCESS NO | Q04857 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | An extracellular matrix protein and upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:308
| ACCESS NO | 101387 |
| GENE | Cox5a |
| DESCRIPTION | Cytochrome c oxidase subunit Va |
| NCBI ENTREZ ACCESS NO | 12858 |
| UNIPROT ACCESS NO | P12787 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in cellular transport and is downregulated in chronic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | BE0003988 |
| MONCLONAL ANTIBODY | Anti-COX5A for Mouse/Rat/Human |
Record No:309
| ACCESS NO | 101393 |
| GENE | Capns1 |
| DESCRIPTION | Calpain small subunit 1 |
| NCBI ENTREZ ACCESS NO | 12336 |
| UNIPROT ACCESS NO | O88456 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Elevated in chronically inflammed lungs. Controls Chloride channel activity for mucus production. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | BE0004144 |
| MONCLONAL ANTIBODY | Anti-Calpain 1 for Mouse/Rat/Human |
Record No:310
| ACCESS NO | 101398 |
| GENE | CD203c |
| DESCRIPTION | Ectonucleotide pyrophosphatase/phosphodiesterase 3 |
| NCBI ENTREZ ACCESS NO | 5169 |
| UNIPROT ACCESS NO | O14638 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Japanese Cedar pollinosis |
| SAMPLE | Blood |
| TECHNIQUES | Flow cytometry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Reduced expression after rush immunotherapy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18504407 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-ENPP3 for Human |
Record No:311
| ACCESS NO | 101400 |
| GENE | Cxcl9 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 9 |
| NCBI ENTREZ ACCESS NO | 17329 |
| UNIPROT ACCESS NO | P18340 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3hours and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MIG for Human |
Record No:312
| ACCESS NO | 101401 |
| GENE | Cxcl10 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 10 |
| NCBI ENTREZ ACCESS NO | 15945 |
| UNIPROT ACCESS NO | P17515 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray and RT PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Significantly expresed in 5 time points after induction with allergenic mould extract. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | Anti-IP10 for Human |
Record No:313
| ACCESS NO | 101406 |
| GENE | Cxcl1 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 1 |
| NCBI ENTREZ ACCESS NO | 14825 |
| UNIPROT ACCESS NO | P09341 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3hours and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:314
| ACCESS NO | 101408 |
| GENE | Ccl7 |
| DESCRIPTION | Chemokine (C-C motif) ligand 7 |
| NCBI ENTREZ ACCESS NO | 20306 |
| UNIPROT ACCESS NO | Q03366 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray and RT PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Significantly upregulated in 5 time points after induction with allergenic mould extract. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MCP3 for Rat/Human |
Record No:315
| ACCESS NO | 101413 |
| GENE | Ccl2 |
| DESCRIPTION | Chemokine (C-C motif) ligand 2 |
| NCBI ENTREZ ACCESS NO | 20296 |
| UNIPROT ACCESS NO | P10148 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0001047 |
| MONCLONAL ANTIBODY | Anti-MCP1 for Mouse/Rat/Human |
Record No:316
| ACCESS NO | 101414 |
| GENE | Ccl17 |
| DESCRIPTION | Chemokine (C-C motif) ligand 17 |
| NCBI ENTREZ ACCESS NO | 20295 |
| UNIPROT ACCESS NO | F6R5P4 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray and RT PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Released during late phase allergic airway responses and overexpressed in mice exposed to allergenic mold extract. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TARC for Human |
Record No:317
| ACCESS NO | 101415 |
| GENE | Clec4e |
| DESCRIPTION | C-type lectin domain family 4 member e |
| NCBI ENTREZ ACCESS NO | 56619 |
| UNIPROT ACCESS NO | Q9R0Q8 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CLEC4E for Human |
Record No:318
| ACCESS NO | 101416 |
| GENE | Ch25h |
| DESCRIPTION | Cholesterol 25-hydroxylase |
| NCBI ENTREZ ACCESS NO | 12642 |
| UNIPROT ACCESS NO | Q9Z0F5 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CH25H(recombinant fraction) |
Record No:319
| ACCESS NO | 101417 |
| GENE | Cfb |
| DESCRIPTION | Complement factor B |
| NCBI ENTREZ ACCESS NO | 14962 |
| UNIPROT ACCESS NO | B8JJM6 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0001701 |
| MONCLONAL ANTIBODY | Anti-Complement factor B for Human |
Record No:320
| ACCESS NO | 101418 |
| GENE | Ccl3 |
| DESCRIPTION | Chemokine (C-C motif) ligand 3 |
| NCBI ENTREZ ACCESS NO | 20302 |
| UNIPROT ACCESS NO | P10855 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0002471 |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 for Human |
Record No:321
| ACCESS NO | 101423 |
| GENE | Ccl19 |
| DESCRIPTION | Chemokine (C-C motif) ligand 19 |
| NCBI ENTREZ ACCESS NO | 24047 |
| UNIPROT ACCESS NO | O70460 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray and RT PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Transiently increased in expression in allergen induced asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 3 beta for Human |
Record No:322
| ACCESS NO | 101424 |
| GENE | Ccl22 |
| DESCRIPTION | Chemokine (C-C motif) ligand 22 |
| NCBI ENTREZ ACCESS NO | 20299 |
| UNIPROT ACCESS NO | O88430 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray and RT PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Released during late phase allergic airway responses and overexpressed in mice exposed to allergenic mold extract. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MDC for Mouse |
Record No:323
| ACCESS NO | 101425 |
| GENE | Cxcl2 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 2 |
| NCBI ENTREZ ACCESS NO | 20310 |
| UNIPROT ACCESS NO | P10889 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray and RT PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Overexpressed in mice exposed to allergenic mold extract. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:324
| ACCESS NO | 101427 |
| GENE | Csf3r |
| DESCRIPTION | Colony stimulating factor 3 receptor |
| NCBI ENTREZ ACCESS NO | 12986 |
| UNIPROT ACCESS NO | P40223 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0000793 |
| MONCLONAL ANTIBODY | Anti-GCSF Receptor for Mouse/Human |
Record No:325
| ACCESS NO | 101434 |
| GENE | Cxcl11 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 11 |
| NCBI ENTREZ ACCESS NO | 56066 |
| UNIPROT ACCESS NO | Q9JHH5 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CXCL11 for Human |
Record No:326
| ACCESS NO | 101435 |
| GENE | Csf2rb |
| DESCRIPTION | Colony stimulating factor 2 receptor beta |
| NCBI ENTREZ ACCESS NO | 12983 |
| UNIPROT ACCESS NO | P26955 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0002115 |
| MONCLONAL ANTIBODY | Anti-IL3RB for Human |
Record No:327
| ACCESS NO | 101436 |
| GENE | Ccr1 |
| DESCRIPTION | Chemokine (C-C motif) receptor 1 |
| NCBI ENTREZ ACCESS NO | 12768 |
| UNIPROT ACCESS NO | P51675 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CCR1 for Human |
Record No:328
| ACCESS NO | 101439 |
| GENE | C3ar1 |
| DESCRIPTION | Complement component 3a receptor 1 |
| NCBI ENTREZ ACCESS NO | 12267 |
| UNIPROT ACCESS NO | O09047 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray and RT PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Expressed on immune cells such as mast cells/eosinophils and basophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-C3a Receptor for Human |
Record No:329
| ACCESS NO | 101444 |
| GENE | Ccl4 |
| DESCRIPTION | Chemokine (C-C motif) ligand 4 |
| NCBI ENTREZ ACCESS NO | 20303 |
| UNIPROT ACCESS NO | P14097 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3hours and 12 hours of fungal allergen induction in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 1 beta for Human |
Record No:330
| ACCESS NO | 101448 |
| GENE | Cxcl5 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 5 |
| NCBI ENTREZ ACCESS NO | 20311 |
| UNIPROT ACCESS NO | P50228 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly upregulated after 3 hours of Allergen induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CXCL5 for Human |
Record No:331
| ACCESS NO | 101455 |
| GENE | Clec4d |
| DESCRIPTION | C-type lectin domain family 4 member d |
| NCBI ENTREZ ACCESS NO | 17474 |
| UNIPROT ACCESS NO | Q9Z2H6 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:332
| ACCESS NO | 101456 |
| GENE | Csf2 |
| DESCRIPTION | Colony stimulating factor 2 (granulocyte-macrophage) |
| NCBI ENTREZ ACCESS NO | 12981 |
| UNIPROT ACCESS NO | P01587 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0002481 |
| MONCLONAL ANTIBODY | Anti-GM-CSF for Mouse/Human |
Record No:333
| ACCESS NO | 101468 |
| GENE | Cd300lf |
| DESCRIPTION | CD300 antigen like family member F |
| NCBI ENTREZ ACCESS NO | 246746 |
| UNIPROT ACCESS NO | Q6SJQ7 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD300 for Human |
Record No:334
| ACCESS NO | 101469 |
| GENE | Csf1 |
| DESCRIPTION | Colony stimulating factor 1 |
| NCBI ENTREZ ACCESS NO | 12977 |
| UNIPROT ACCESS NO | P07141 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MCSF for Human |
Record No:335
| ACCESS NO | 101487 |
| GENE | Cd83 |
| DESCRIPTION | CD83 antigen |
| NCBI ENTREZ ACCESS NO | 12522 |
| UNIPROT ACCESS NO | O88324 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD83 for Mouse/Rat/Human |
Record No:336
| ACCESS NO | 101495 |
| GENE | Csf1 |
| DESCRIPTION | Colony stimulating factor 1 (macrophage) |
| NCBI ENTREZ ACCESS NO | 12977 |
| UNIPROT ACCESS NO | P07141 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MCSF for Human |
Record No:337
| ACCESS NO | 101506 |
| GENE | Cd274 |
| DESCRIPTION | CD274 antigen |
| NCBI ENTREZ ACCESS NO | 60533 |
| UNIPROT ACCESS NO | Q9EP73 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD274 for Mouse/Rat/Human |
Record No:338
| ACCESS NO | 101515 |
| GENE | Cd44 |
| DESCRIPTION | CD44 antigen |
| NCBI ENTREZ ACCESS NO | 12505 |
| UNIPROT ACCESS NO | Q80X37 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0001113 |
| MONCLONAL ANTIBODY | Anti-CD44 for Mouse/Human |
Record No:339
| ACCESS NO | 101518 |
| GENE | Cd79a |
| DESCRIPTION | CD79A antigen |
| NCBI ENTREZ ACCESS NO | 12518 |
| UNIPROT ACCESS NO | P11911 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD79a for Human |
Record No:340
| ACCESS NO | 101520 |
| GENE | Csf2rb2 |
| DESCRIPTION | Colony stimulating factor 2 receptor beta 2 low-affinity |
| NCBI ENTREZ ACCESS NO | 12984 |
| UNIPROT ACCESS NO | P26954 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:341
| ACCESS NO | 101525 |
| GENE | Clip4 |
| DESCRIPTION | AP-GLY domain containing linker protein family member 4 |
| NCBI ENTREZ ACCESS NO | 78785 |
| UNIPROT ACCESS NO | Q8CI96 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:342
| ACCESS NO | 101529 |
| GENE | CRP |
| DESCRIPTION | C-reactive protein |
| NCBI ENTREZ ACCESS NO | 1401 |
| UNIPROT ACCESS NO | P02741 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Exhaled breath condensate |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Significantly higher in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18513240 |
| DRUG TARGET | BE0000877 |
| MONCLONAL ANTIBODY | Anti-C Reactive Protein for Human |
Record No:343
| ACCESS NO | 101531 |
| GENE | CRP |
| DESCRIPTION | C-reactive protein |
| NCBI ENTREZ ACCESS NO | 1401 |
| UNIPROT ACCESS NO | P02741 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Venous blood |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Decreased in asthmatics after etanercept administration. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18245148 |
| DRUG TARGET | BE0000877 |
| MONCLONAL ANTIBODY | Anti-C Reactive Protein for Human |
Record No:344
| ACCESS NO | 101555 |
| GENE | CLCA3 |
| DESCRIPTION | Chloride channel calcium activated 3 |
| NCBI ENTREZ ACCESS NO | 23844 |
| UNIPROT ACCESS NO | Q9D7Z6 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Expressed in epithelial cells and involved in mucus production. Its expression is dependant of IL 13 signalling. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:345
| ACCESS NO | 101557 |
| GENE | CHI3L3 |
| DESCRIPTION | Chitinase-like 3 |
| NCBI ENTREZ ACCESS NO | 12655 |
| UNIPROT ACCESS NO | O35744 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Expressed during both OVA and IL 13 challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:346
| ACCESS NO | 101568 |
| GENE | CTSK |
| DESCRIPTION | Cathepsin K |
| NCBI ENTREZ ACCESS NO | 13038 |
| UNIPROT ACCESS NO | P55097 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Induced by both OVA challenge and IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | BE0003417 |
| MONCLONAL ANTIBODY | Anti-Cathepsin K for Human |
Record No:347
| ACCESS NO | 101573 |
| GENE | C3 |
| DESCRIPTION | Complement component 3 |
| NCBI ENTREZ ACCESS NO | 12266 |
| UNIPROT ACCESS NO | P01027 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in Innate immunity and induced by both OVA challenge and IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | BE0003455 |
| MONCLONAL ANTIBODY | Anti-C3 for Mouse |
Record No:348
| ACCESS NO | 101579 |
| GENE | Cd83 |
| DESCRIPTION | CD83 antigen |
| NCBI ENTREZ ACCESS NO | 12522 |
| UNIPROT ACCESS NO | O88324 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Immune related gene and expressed in IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD83 for Mouse/Rat/Human |
Record No:349
| ACCESS NO | 101580 |
| GENE | Cd14 |
| DESCRIPTION | CD14 antigen |
| NCBI ENTREZ ACCESS NO | 12475 |
| UNIPROT ACCESS NO | P10810 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Immune related gene and expressed in IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD14 for Human |
Record No:350
| ACCESS NO | 101598 |
| GENE | Csf1 |
| DESCRIPTION | Colony stimulating factor 1 |
| NCBI ENTREZ ACCESS NO | 12977 |
| UNIPROT ACCESS NO | P07141 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in secreted signal transduction and expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MCSF for human |
Record No:351
| ACCESS NO | 101601 |
| GENE | Col6a1 |
| DESCRIPTION | Procollagen type VI alpha 1 |
| NCBI ENTREZ ACCESS NO | 12833 |
| UNIPROT ACCESS NO | Q04857 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Present in extracellular matrix and expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:352
| ACCESS NO | 101602 |
| GENE | Col1A1 |
| DESCRIPTION | Collagen type 1 alpha 1 |
| NCBI ENTREZ ACCESS NO | 12842 |
| UNIPROT ACCESS NO | P11087 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Present in extracellular matrix and expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Collagen I for Mouse/Human |
Record No:353
| ACCESS NO | 101603 |
| GENE | COLA2 |
| DESCRIPTION | Procollagen type I alpha 2 |
| NCBI ENTREZ ACCESS NO | 12843 |
| UNIPROT ACCESS NO | Q01149 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Present in extracellular matrix and expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:354
| ACCESS NO | 101604 |
| GENE | Col6a2 |
| DESCRIPTION | Procollagen type VI alpha 2 |
| NCBI ENTREZ ACCESS NO | 12834 |
| UNIPROT ACCESS NO | Q02788 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Present in extracellular matrix and expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Collagen VI alpha 2 for Mouse/Human |
Record No:355
| ACCESS NO | 101611 |
| GENE | Ckmt1 |
| DESCRIPTION | Creatine kinase mitochondrial 1 |
| NCBI ENTREZ ACCESS NO | 12716 |
| UNIPROT ACCESS NO | P30275 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in metabolism and expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Creatine kinase MT for Mouse/Rat/Rabbit. |
Record No:356
| ACCESS NO | 101615 |
| GENE | Car2 |
| DESCRIPTION | Carbonic anhydrase 2 |
| NCBI ENTREZ ACCESS NO | 12349 |
| UNIPROT ACCESS NO | P00920 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in metabolism and expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | BE0000322 |
| MONCLONAL ANTIBODY | Anti-Carbonic Anhydrase II for Mouse/Rat/Human |
Record No:357
| ACCESS NO | 101625 |
| GENE | Cish |
| DESCRIPTION | Cytokine inducible SH2-containing protein |
| NCBI ENTREZ ACCESS NO | 12700 |
| UNIPROT ACCESS NO | Q62225 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:358
| ACCESS NO | 101633 |
| GENE | CCL17 |
| DESCRIPTION | Chemokine (C-C motif) ligand 17 |
| NCBI ENTREZ ACCESS NO | 6361 |
| UNIPROT ACCESS NO | Q92583 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral Blood Mononuclear cells |
| TECHNIQUES | Microarray and RT PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Revealed increased expression in IL 13 stimulated human beings. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17564846 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TARC for Human |
Record No:359
| ACCESS NO | 101634 |
| GENE | CCL26 |
| DESCRIPTION | Chemokine (C-C motif) ligand 26 |
| NCBI ENTREZ ACCESS NO | 10344 |
| UNIPROT ACCESS NO | Q9Y258 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral Blood Mononuclear cells |
| TECHNIQUES | Microarray and RT PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Overexpressed in IL 13 stimulated human beings. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17564846 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:360
| ACCESS NO | 101635 |
| GENE | CCL23 |
| DESCRIPTION | Chemokine (C-C motif) ligand 23 |
| NCBI ENTREZ ACCESS NO | 6368 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral Blood Mononuclear cells |
| TECHNIQUES | Microarray and RT PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Revealed increased expression in IL 13 stimulated human beings. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17564846 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 3 for Human |
Record No:361
| ACCESS NO | 101636 |
| GENE | CCL22 |
| DESCRIPTION | Chemokine (C-C motif) ligand 22 |
| NCBI ENTREZ ACCESS NO | 6367 |
| UNIPROT ACCESS NO | O00626 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral Blood Mononuclear cells |
| TECHNIQUES | Microarray and RT PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Revealed increased expression in IL 13 stimulated human beings. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17564846 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MDCÂ for mouse |
Record No:362
| ACCESS NO | 101646 |
| GENE | CD44 |
| DESCRIPTION | CD44 molecule |
| NCBI ENTREZ ACCESS NO | 960 |
| UNIPROT ACCESS NO | P16070 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Insect allergy(Bee venom immunotherapy) |
| SAMPLE | Peripheral Blood Mononuclear cells |
| TECHNIQUES | Gene chip microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | A receptor for osteopontin. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15867867 |
| DRUG TARGET | BE0001113 |
| MONCLONAL ANTIBODY | Anti-CD44 for Mouse/Human |
Record No:363
| ACCESS NO | 101652 |
| GENE | Cyb5 |
| DESCRIPTION | Cytochrome b-5 |
| NCBI ENTREZ ACCESS NO | 109672 |
| UNIPROT ACCESS NO | P56395 |
| ORGANISM | Male BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | 2D electrophoresis and MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16100447 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Cytochrome b5 for Human |
Record No:364
| ACCESS NO | 101656 |
| GENE | Chil3 |
| DESCRIPTION | Chitinase 3-like 3 (YM1) |
| NCBI ENTREZ ACCESS NO | 12655 |
| UNIPROT ACCESS NO | O35744 |
| ORGANISM | Male BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | 2D electrophoresis and MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16100447 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:365
| ACCESS NO | 101661 |
| GENE | Chil4 |
| DESCRIPTION | Chitinase 3-like 4 |
| NCBI ENTREZ ACCESS NO | 104183 |
| UNIPROT ACCESS NO | Q91Z98 |
| ORGANISM | Male BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | 2D electrophoresis and MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16100447 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:366
| ACCESS NO | 101697 |
| GENE | CD14 |
| DESCRIPTION | Monocyte differentiation antigen CD14 |
| NCBI ENTREZ ACCESS NO | 929 |
| UNIPROT ACCESS NO | P08571 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD146 [EPR3208] for Mouse/Rat/Human |
Record No:367
| ACCESS NO | 101701 |
| GENE | CCL17 |
| DESCRIPTION | Small inducible cytokine A17 (CCL17) |
| NCBI ENTREZ ACCESS NO | 6361 |
| UNIPROT ACCESS NO | Q92583 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This chemokine is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:368
| ACCESS NO | 101707 |
| GENE | CLC |
| DESCRIPTION | Eosinophil lysophospholipase |
| NCBI ENTREZ ACCESS NO | 1178 |
| UNIPROT ACCESS NO | Q05315 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This eosinophilic granule protein is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:369
| ACCESS NO | 101709 |
| GENE | CRISP3 (CRISP-3) |
| DESCRIPTION | Cysteine-rich secretory protein 3 |
| NCBI ENTREZ ACCESS NO | 10321 |
| UNIPROT ACCESS NO | P54108 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This neutrophilic granule protein is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CRISP3 [LV-2A2] for Human |
Record No:370
| ACCESS NO | 101712 |
| GENE | CFH |
| DESCRIPTION | Complement factor H |
| NCBI ENTREZ ACCESS NO | 3075 |
| UNIPROT ACCESS NO | P08603 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This complement factor is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:371
| ACCESS NO | 101713 |
| GENE | CFB |
| DESCRIPTION | Complement factor B preproprotein |
| NCBI ENTREZ ACCESS NO | 629 |
| UNIPROT ACCESS NO | P00751 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This complement factor is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0001701 |
| MONCLONAL ANTIBODY | Anti-Factor B [KT21] for Human |
Record No:372
| ACCESS NO | 101714 |
| GENE | C6 |
| DESCRIPTION | Complement C6 |
| NCBI ENTREZ ACCESS NO | 729 |
| UNIPROT ACCESS NO | P13671 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This complement factor is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:373
| ACCESS NO | 101715 |
| GENE | C8A |
| DESCRIPTION | Complement component C8 # chain |
| NCBI ENTREZ ACCESS NO | 731 |
| UNIPROT ACCESS NO | P07357 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This complement factor is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:374
| ACCESS NO | 101716 |
| GENE | C8G |
| DESCRIPTION | Complement component C8 # chain |
| NCBI ENTREZ ACCESS NO | 733 |
| UNIPROT ACCESS NO | P07360 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This complement factor is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0003266 |
| MONCLONAL ANTIBODY | Anti-C8 [056B-373] for Human |
Record No:375
| ACCESS NO | 101717 |
| GENE | CFD |
| DESCRIPTION | Complement factor D |
| NCBI ENTREZ ACCESS NO | 1675 |
| UNIPROT ACCESS NO | P00746 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This complement factor is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0001840 |
| MONCLONAL ANTIBODY | Anti-C8G [EPR11274] for Mouse/Rat/Human |
Record No:376
| ACCESS NO | 101718 |
| GENE | C1QC |
| DESCRIPTION | Complement component C1q |
| NCBI ENTREZ ACCESS NO | 714 |
| UNIPROT ACCESS NO | P02747 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This complement factor is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0002096 |
| MONCLONAL ANTIBODY | Anti-C1QC [EPR2984Y] for Human |
Record No:377
| ACCESS NO | 101723 |
| GENE | CTSD |
| DESCRIPTION | Cathepsin D |
| NCBI ENTREZ ACCESS NO | 1509 |
| UNIPROT ACCESS NO | P07339 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protease is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000941 |
| MONCLONAL ANTIBODY | Anti-Cathepsin D [4G2] for Human |
Record No:378
| ACCESS NO | 101727 |
| GENE | CPB2 |
| DESCRIPTION | Carboxypeptidase B2 |
| NCBI ENTREZ ACCESS NO | 1361 |
| UNIPROT ACCESS NO | Q96IY4 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protease is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0003407 |
| MONCLONAL ANTIBODY | Anti-Carboxypeptidase B2 [EPR7858]Â for Mouse/Rat/Human |
Record No:379
| ACCESS NO | 101728 |
| GENE | CAMP |
| DESCRIPTION | CAP18 |
| NCBI ENTREZ ACCESS NO | 820 |
| UNIPROT ACCESS NO | P49913 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protease is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0004543 |
| MONCLONAL ANTIBODY | Anti-cAMP [SPM486] for Mouse/Human |
Record No:380
| ACCESS NO | 101730 |
| GENE | CPN1 |
| DESCRIPTION | Carboxypeptidase N catalytic chain |
| NCBI ENTREZ ACCESS NO | 1369 |
| UNIPROT ACCESS NO | P15169 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protease is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:381
| ACCESS NO | 101733 |
| GENE | CAT |
| DESCRIPTION | Catalase |
| NCBI ENTREZ ACCESS NO | 847 |
| UNIPROT ACCESS NO | P04040 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0001207 |
| MONCLONAL ANTIBODY | Anti-Catalase [1B6] for Rat/Human |
Record No:382
| ACCESS NO | 101740 |
| GENE | CD5L |
| DESCRIPTION | CD5L |
| NCBI ENTREZ ACCESS NO | 922 |
| UNIPROT ACCESS NO | CD5L |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD5L for human |
Record No:383
| ACCESS NO | 101755 |
| GENE | CDA |
| DESCRIPTION | Cytidine deaminase (cytidine aminohydrolase) |
| NCBI ENTREZ ACCESS NO | 978 |
| UNIPROT ACCESS NO | Q71UE9 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0002443 |
| MONCLONAL ANTIBODY | Anti-CDADC1 for Rat/Human |
Record No:384
| ACCESS NO | 101757 |
| GENE | CHI3L2 |
| DESCRIPTION | Chitinase 3-like 2 |
| NCBI ENTREZ ACCESS NO | 1117 |
| UNIPROT ACCESS NO | Q15782 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This local matrix protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:385
| ACCESS NO | 101759 |
| GENE | CHI3L1 |
| DESCRIPTION | Chitinase 3-like 1 (cartilage glycoprotein-39) |
| NCBI ENTREZ ACCESS NO | 1116 |
| UNIPROT ACCESS NO | P36222 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This local matrix protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CHI3L1 [AT4A3] for Human |
Record No:386
| ACCESS NO | 101774 |
| GENE | CRP |
| DESCRIPTION | C-reactive protein |
| NCBI ENTREZ ACCESS NO | 1401 |
| UNIPROT ACCESS NO | P02741 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This acute phase protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000877 |
| MONCLONAL ANTIBODY | Anti-C Reactive Protein [CRP135] for Human |
Record No:387
| ACCESS NO | 101778 |
| GENE | CLU |
| DESCRIPTION | Clusterin |
| NCBI ENTREZ ACCESS NO | 1191 |
| UNIPROT ACCESS NO | E5RJD6 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This apolipoprotein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:388
| ACCESS NO | 101788 |
| GENE | CP |
| DESCRIPTION | Ceruloplasmin |
| NCBI ENTREZ ACCESS NO | 1356 |
| UNIPROT ACCESS NO | D6RE86 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This serum protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0001140 |
| MONCLONAL ANTIBODY | N/A |
Record No:389
| ACCESS NO | 101804 |
| GENE | COTL1 |
| DESCRIPTION | Coactosin-like protein |
| NCBI ENTREZ ACCESS NO | 23406 |
| UNIPROT ACCESS NO | Q14019 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This cytoskeletal protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-COTL1 for Human |
Record No:390
| ACCESS NO | 101821 |
| GENE | CNTN1 |
| DESCRIPTION | alpha-B motif-binding phosphoprotein |
| NCBI ENTREZ ACCESS NO | 1272 |
| UNIPROT ACCESS NO | Q12860 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:391
| ACCESS NO | 101829 |
| GENE | CD55 |
| DESCRIPTION | Decay-acceleration factor |
| NCBI ENTREZ ACCESS NO | 1604 |
| UNIPROT ACCESS NO | P08174 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is down regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000929 |
| MONCLONAL ANTIBODY | Anti-CD55 [EPR6689] for Human |
Record No:392
| ACCESS NO | 101832 |
| GENE | CNTN6 |
| DESCRIPTION | Neural adhesion molecule NB-3 |
| NCBI ENTREZ ACCESS NO | 27255 |
| UNIPROT ACCESS NO | Q9UQ52 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is down regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:393
| ACCESS NO | 101833 |
| GENE | CNTN1 |
| DESCRIPTION | Contactin precursor (glycoprotein gP135) |
| NCBI ENTREZ ACCESS NO | 1272 |
| UNIPROT ACCESS NO | Q12860 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is down regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:394
| ACCESS NO | 101844 |
| GENE | C3 |
| DESCRIPTION | Complement C3/C3 |
| NCBI ENTREZ ACCESS NO | 718 |
| UNIPROT ACCESS NO | P01024 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucus |
| TECHNIQUES | LC-MS/MS and western blot |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It showed 2.3 fold upregulation in rhinitis patients. It plays a role in the inflammatory process of allergic rhinitis through activation of the complement system. It is a marker of plasma exudation in acute reactions to allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24290289 |
| DRUG TARGET | BE0003455 |
| MONCLONAL ANTIBODY | N/A |
Record No:395
| ACCESS NO | 101867 |
| GENE | CD5L |
| DESCRIPTION | CD5 molecule-like |
| NCBI ENTREZ ACCESS NO | 922 |
| UNIPROT ACCESS NO | O43866 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Plasma |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF and Immunoblot |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated level of this protein causes eosinophilia by inhibiting apoptosis or promoting the proliferation of eosinophils either in combination with or without IL5. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19116453 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD5L for Human |
Record No:396
| ACCESS NO | 101869 |
| GENE | C4B |
| DESCRIPTION | Complement component 4B |
| NCBI ENTREZ ACCESS NO | 721 |
| UNIPROT ACCESS NO | P0C0L5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Plasma |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is down regulated in atopic dermatitis patient. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19116453 |
| DRUG TARGET | BE0004686 |
| MONCLONAL ANTIBODY | Anti-C4b for Human |
Record No:397
| ACCESS NO | 101873 |
| GENE | CPNE1 |
| DESCRIPTION | Copine I |
| NCBI ENTREZ ACCESS NO | 8904 |
| UNIPROT ACCESS NO | Q99829 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Fibroblast |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic fibroblasts comparative to normal fibroblasts. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15468290 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CPNE1 for Human |
Record No:398
| ACCESS NO | 101884 |
| GENE | CAPG |
| DESCRIPTION | Macrophage capping protein |
| NCBI ENTREZ ACCESS NO | 822 |
| UNIPROT ACCESS NO | P40121 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Fibroblast |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic fibroblasts comparative to normal fibroblasts. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15468290 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Actin Regulatory Protein CAPG for Human |
Record No:399
| ACCESS NO | 101900 |
| GENE | CHM |
| DESCRIPTION | Rab proteins geranyltransferase component A 1 |
| NCBI ENTREZ ACCESS NO | 1121 |
| UNIPROT ACCESS NO | P24386 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | BE0004074 |
| MONCLONAL ANTIBODY | N/A |
Record No:400
| ACCESS NO | 101903 |
| GENE | CAT |
| DESCRIPTION | Catalase |
| NCBI ENTREZ ACCESS NO | 847 |
| UNIPROT ACCESS NO | P04040 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | BE0001207 |
| MONCLONAL ANTIBODY | Anti-Catalase for Human/Rat |
Record No:401
| ACCESS NO | 101905 |
| GENE | COIL |
| DESCRIPTION | Coilin (p80) |
| NCBI ENTREZ ACCESS NO | 8161 |
| UNIPROT ACCESS NO | P38432 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Coilin for Human |
Record No:402
| ACCESS NO | 101908 |
| GENE | CCNA2 |
| DESCRIPTION | Cyclin A2 |
| NCBI ENTREZ ACCESS NO | 890 |
| UNIPROT ACCESS NO | P20248 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | BE0003734 |
| MONCLONAL ANTIBODY | Anti-Cyclin A2 for Mousse/Rat/Human |
Record No:403
| ACCESS NO | 101914 |
| GENE | CDC25A |
| DESCRIPTION | M-phase inducer phosphatase 1 (Cdc25A) |
| NCBI ENTREZ ACCESS NO | 993 |
| UNIPROT ACCESS NO | P30304 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Cdc25A for Rat/Human |
Record No:404
| ACCESS NO | 101918 |
| GENE | CPNE7 |
| DESCRIPTION | Copine VII |
| NCBI ENTREZ ACCESS NO | 27132 |
| UNIPROT ACCESS NO | Q9UBL6 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CPNE7 for Human |
Record No:405
| ACCESS NO | 101919 |
| GENE | CNN3 |
| DESCRIPTION | Calponin 3 |
| NCBI ENTREZ ACCESS NO | 1266 |
| UNIPROT ACCESS NO | Q15417 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:406
| ACCESS NO | 101927 |
| GENE | CAPZB |
| DESCRIPTION | F-actin capping protein beta subunit |
| NCBI ENTREZ ACCESS NO | 832 |
| UNIPROT ACCESS NO | P47756 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CAPZB for Mouse/Rat/Human |
Record No:407
| ACCESS NO | 101931 |
| GENE | COL19A1 |
| DESCRIPTION | Collagen alpha -1 |
| NCBI ENTREZ ACCESS NO | 1310 |
| UNIPROT ACCESS NO | Q14993 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:408
| ACCESS NO | 101940 |
| GENE | CAST |
| DESCRIPTION | Calpastatin |
| NCBI ENTREZ ACCESS NO | 831 |
| UNIPROT ACCESS NO | P20810 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Up regulated in asthma. Involved in cellular assembly and organisation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | BE0000904 |
| MONCLONAL ANTIBODY | Anti-Calpastatin for Rat/Rabbit/Human |
Record No:409
| ACCESS NO | 101941 |
| GENE | CREB5 |
| DESCRIPTION | cAMP responsive element binding protein 5 |
| NCBI ENTREZ ACCESS NO | 9586 |
| UNIPROT ACCESS NO | Q02930 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CREB5 for Mouse/Rat/Human |
Record No:410
| ACCESS NO | 101942 |
| GENE | CSDE1 |
| DESCRIPTION | Cold shock domain containing E1 |
| NCBI ENTREZ ACCESS NO | 7812 |
| UNIPROT ACCESS NO | O75534 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Up regulated in asthma. Involved in cellular assembly and organisation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:411
| ACCESS NO | 101952 |
| GENE | C1orf24 |
| DESCRIPTION | Chromosome 1 open reading frame 24 |
| NCBI ENTREZ ACCESS NO | 116496 |
| UNIPROT ACCESS NO | Q9BZQ8 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:412
| ACCESS NO | 101962 |
| GENE | CSF3R |
| DESCRIPTION | Colony stimulating factor 3 receptor |
| NCBI ENTREZ ACCESS NO | 1441 |
| UNIPROT ACCESS NO | Q99062 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthmatic children. Involved in cellular assembly and organisation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | BE0000793 |
| MONCLONAL ANTIBODY | Anti-GCSF Receptor for Mouse/Human |
Record No:413
| ACCESS NO | 101966 |
| GENE | CD200 |
| DESCRIPTION | CD200 antigen |
| NCBI ENTREZ ACCESS NO | 4345 |
| UNIPROT ACCESS NO | P41217 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Significantly reduced in exthma excacerbation. It is expressed by thymocytes and T cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD200 for Human |
Record No:414
| ACCESS NO | 101968 |
| GENE | CD40L |
| DESCRIPTION | CD40 ligand |
| NCBI ENTREZ ACCESS NO | 959 |
| UNIPROT ACCESS NO | P29965 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy (Immunotherapy of pollen allergy) |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Flow cytometry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Downregulated after specific immunotherapy.Interacts with CD40 and is the key signal for isotype class switching towards IgE. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24834772 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD40L for Mouse/Human |
Record No:415
| ACCESS NO | 101972 |
| GENE | Car4 |
| DESCRIPTION | Carbonic anhydrase 4 |
| NCBI ENTREZ ACCESS NO | 12351 |
| UNIPROT ACCESS NO | Q64444 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma (eosinophilia) |
| SAMPLE | Eosinophil |
| TECHNIQUES | RT-PCR and immunohistochemistry |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Highly expressed after allergen exposure and is involved in controlling lung transcriptome. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24808371 |
| DRUG TARGET | BE0000535 |
| MONCLONAL ANTIBODY | N/A |
Record No:416
| ACCESS NO | 101991 |
| GENE | CCNB2 |
| DESCRIPTION | Cyclin B2 |
| NCBI ENTREZ ACCESS NO | 9133 |
| UNIPROT ACCESS NO | O95067 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in patients with allergic rhinitis with or without asthma in the upper airways. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Cyclin B2 for Mouse/Rat/Human |
Record No:417
| ACCESS NO | 101996 |
| GENE | CLN8 |
| DESCRIPTION | Ceroid-lipofuscinosis neuronal 8 |
| NCBI ENTREZ ACCESS NO | 2055 |
| UNIPROT ACCESS NO | Q9UBY8 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in the upper airways in patients with allergic rhinitis and asthma. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CLN8 for Mouse/Rat/Human |
Record No:418
| ACCESS NO | 101997 |
| GENE | CFB |
| DESCRIPTION | Complement factor B |
| NCBI ENTREZ ACCESS NO | 629 |
| UNIPROT ACCESS NO | P00751 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in lower airways in patients suffering from allergic rhinitis with or without asthma. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | BE0001701 |
| MONCLONAL ANTIBODY | Anti-Factor B for Human |
Record No:419
| ACCESS NO | 102001 |
| GENE | C4orf32 |
| DESCRIPTION | Chromosome 4 open reading frame 32 |
| NCBI ENTREZ ACCESS NO | 132720 |
| UNIPROT ACCESS NO | Q8N8J7 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in lower airways in patients suffering from allergic rhinitis with or without asthma. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:420
| ACCESS NO | 102004 |
| GENE | CYP1B1 |
| DESCRIPTION | Cytochrome P450 family 1 subfamily B polypeptide 1 |
| NCBI ENTREZ ACCESS NO | 1545 |
| UNIPROT ACCESS NO | Q16678 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in lower airways in patients suffering from allergic rhinitis with or without asthma. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | BE0001111 |
| MONCLONAL ANTIBODY | Anti-CYP1B1 for Mouse/Rat/Human |
Record No:421
| ACCESS NO | 102012 |
| GENE | CTH |
| DESCRIPTION | Cystathionase |
| NCBI ENTREZ ACCESS NO | 1491 |
| UNIPROT ACCESS NO | P32929 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in the lower airways in patients with allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | BE0000791 |
| MONCLONAL ANTIBODY | N/A |
Record No:422
| ACCESS NO | 102016 |
| GENE | CXCL10 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 10 |
| NCBI ENTREZ ACCESS NO | 3627 |
| UNIPROT ACCESS NO | P02778 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Primary nasal and bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in asthma(data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | Anti-IP10 for Mouse/Human |
Record No:423
| ACCESS NO | 102025 |
| GENE | C16orf45 |
| DESCRIPTION | Chromosome 16 open reading frame 45 |
| NCBI ENTREZ ACCESS NO | 89927 |
| UNIPROT ACCESS NO | Q96MC5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma.(Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-C16orf45 for Rat/Human |
Record No:424
| ACCESS NO | 102026 |
| GENE | C1orf133 |
| DESCRIPTION | Chromosome 1 open reading frame 133 |
| NCBI ENTREZ ACCESS NO | 574036 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma.(Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:425
| ACCESS NO | 102027 |
| GENE | CHST9 |
| DESCRIPTION | Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 |
| NCBI ENTREZ ACCESS NO | 83539 |
| UNIPROT ACCESS NO | Q7L1S5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma.(Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:426
| ACCESS NO | 102050 |
| GENE | C1orf38 |
| DESCRIPTION | Chromosome 1 open reading frame 38 |
| NCBI ENTREZ ACCESS NO | 9473 |
| UNIPROT ACCESS NO | Q5TEJ8 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Nasal epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:427
| ACCESS NO | 102051 |
| GENE | CTSC |
| DESCRIPTION | Cathepsin C |
| NCBI ENTREZ ACCESS NO | 1075 |
| UNIPROT ACCESS NO | P53634 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Nasal epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:428
| ACCESS NO | 102071 |
| GENE | CASP3 |
| DESCRIPTION | Caspase 3 |
| NCBI ENTREZ ACCESS NO | 836 |
| UNIPROT ACCESS NO | P42574 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in apoptosis. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | BE0001162 |
| MONCLONAL ANTIBODY | Anti-Caspase-3 for Rat/Human |
Record No:429
| ACCESS NO | 102073 |
| GENE | CD200R1 |
| DESCRIPTION | CD200 receptor 1 |
| NCBI ENTREZ ACCESS NO | 131450 |
| UNIPROT ACCESS NO | Q8TD46 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in inflammation and immunoregulation. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD200R for Rat/Mouse |
Record No:430
| ACCESS NO | 102074 |
| GENE | CISH |
| DESCRIPTION | Cytokine inducible SH2-containing protein |
| NCBI ENTREZ ACCESS NO | 1154 |
| UNIPROT ACCESS NO | Q9NSE2 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthma. Involved in inflammation and immunoregulation. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:431
| ACCESS NO | 102075 |
| GENE | CSF1 |
| DESCRIPTION | Colony stimulating factor 9 |
| NCBI ENTREZ ACCESS NO | 1435 |
| UNIPROT ACCESS NO | P09603 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in inflammation and immunoregulation. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MCSF for Human |
Record No:432
| ACCESS NO | 102089 |
| GENE | CNKSR2 |
| DESCRIPTION | Connector enhancer of kinase suppressor of Ras 2 |
| NCBI ENTREZ ACCESS NO | 22866 |
| UNIPROT ACCESS NO | Q8WXI2 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in signal transduction and may regulate RAS signalling pathways. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:433
| ACCESS NO | 102102 |
| GENE | CEACAM1 |
| DESCRIPTION | Carcinoembryonic Ag-related cell adhesion 1 |
| NCBI ENTREZ ACCESS NO | 634 |
| UNIPROT ACCESS NO | P13688 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Activated in asthma. Involved in TCR signalling. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | BE0000107 |
| MONCLONAL ANTIBODY | Anti-CEACAM1 for Human |
Record No:434
| ACCESS NO | 102108 |
| GENE | CCL1 |
| DESCRIPTION | C-C chemokine ligand 1 |
| NCBI ENTREZ ACCESS NO | 6346 |
| UNIPROT ACCESS NO | P22362 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in TH2 regulation and function. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:435
| ACCESS NO | 102128 |
| GENE | CAMK2D |
| DESCRIPTION | Calcium-dependent protein kinase II delta |
| NCBI ENTREZ ACCESS NO | 817 |
| UNIPROT ACCESS NO | Q13557 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthma.Involved in beta catenin/wnt signalling pathway. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | BE0004108 |
| MONCLONAL ANTIBODY | Anti-CaMKII delta for Mouse/Human |
Record No:436
| ACCESS NO | 102138 |
| GENE | CX3CR1 |
| DESCRIPTION | Chemokine (C-X3-C motif) |
| NCBI ENTREZ ACCESS NO | 1524 |
| UNIPROT ACCESS NO | P49238 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Bronchial Biopsy |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | GSE41649 |
| REFERENCE | 19842841 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CX3CR1 for Human |
Record No:437
| ACCESS NO | 102142 |
| GENE | CEACAM5 |
| DESCRIPTION | Carcinoembryonic antigen-related cell adhesion molecule 5 |
| NCBI ENTREZ ACCESS NO | 1048 |
| UNIPROT ACCESS NO | P06731 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Bronchial Biopsy |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | GSE41649 |
| REFERENCE | 19842841 |
| DRUG TARGET | BE0004224 |
| MONCLONAL ANTIBODY | Anti-Carcino Embryonic Antigen CEA for Human |
Record No:438
| ACCESS NO | 102145 |
| GENE | CTSC |
| DESCRIPTION | Cathepsin C |
| NCBI ENTREZ ACCESS NO | 1075 |
| UNIPROT ACCESS NO | P53634 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Bronchial Biopsy |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergic asthma. It is a proteolytic enzyme. |
| GEO_PRIDE_ACCESS_NO | GSE41649 |
| REFERENCE | 19842841 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:439
| ACCESS NO | 102153 |
| GENE | C7 |
| DESCRIPTION | Complement component 7 |
| NCBI ENTREZ ACCESS NO | 730 |
| UNIPROT ACCESS NO | P10643 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Bronchial Biopsy |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | GSE41649 |
| REFERENCE | 19842841 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-C7 for Mouse/Rat/Human |