BROWSE RESULT OF D
37 Records |
ACCESS NO | 100036 |
GENE | DNAJB1 |
DESCRIPTION | DnaJ (Hsp40) homolog subfamily B-member 1 |
NCBI ENTREZ ACCESS NO | 3337 |
UNIPROT ACCESS NO | P25685 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
SAMPLE | CD2+ cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | It protect cells from inflammatory molecules such as reactive oxygen species and are protective against pulmonary inflammations. |
GEO_PRIDE_ACCESS_NO | GSE7894 |
REFERENCE | 19001005 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:2
ACCESS NO | 100047 |
GENE | DDX3Y |
DESCRIPTION | DEAD (Asp-Glu-Ala-Asp) box helicase 3 Y-linked |
NCBI ENTREZ ACCESS NO | 8653 |
UNIPROT ACCESS NO | O15523 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
SAMPLE | CD2+ cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene is upregulated more in high SEC group. |
GEO_PRIDE_ACCESS_NO | GSE7894 |
REFERENCE | 19001005 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:3
ACCESS NO | 100157 |
GENE | DUSP6 |
DESCRIPTION | Dual specificity phosphatase 6 |
NCBI ENTREZ ACCESS NO | 1848 |
UNIPROT ACCESS NO | Q16828 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-DUSP6 for Mouse/Rat/Human |
Record No:4
ACCESS NO | 100185 |
GENE | DEFB1 |
DESCRIPTION | Defensin beta 1 |
NCBI ENTREZ ACCESS NO | 1672 |
UNIPROT ACCESS NO | P60022 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is a immunity and defense related protein significantly down regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:5
ACCESS NO | 100218 |
GENE | DMBT1 |
DESCRIPTION | Deleted in malignant brain tumours 1 |
NCBI ENTREZ ACCESS NO | 1755 |
UNIPROT ACCESS NO | Q9UGM3 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene codes for a transporter significantly up regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-gp340 for Human |
Record No:6
ACCESS NO | 100262 |
GENE | DLG1 |
DESCRIPTION | Discs-large homolog 1 (Drosophila) |
NCBI ENTREZ ACCESS NO | 1739 |
UNIPROT ACCESS NO | Q12959 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
SAMPLE | Primary bronchial epithelial cells |
TECHNIQUES | Affymetrix GeneChip Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is a cell cycle regulatory protein down regulated after rhinoviral infection. |
GEO_PRIDE_ACCESS_NO | GSE13396 |
REFERENCE | 19710636 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:7
ACCESS NO | 100317 |
GENE | Dusp1 |
DESCRIPTION | Dual specificity phosphatase 1 |
NCBI ENTREZ ACCESS NO | 114856 |
UNIPROT ACCESS NO | Q64623 |
ORGANISM | Rat |
DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
SAMPLE | Lung tissue |
TECHNIQUES | Serial analysis of gene expression (SAGE) and qRT- |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It was significantly elevated in this study whic is demonstrating that Dusp1 may function as a negative regulator to alleviate and counteract the OVA challenge signals transmitted by the MAPK pathway. The Dusp1 gene is therefore a potential target for the development of novel anti-inflammatory drugs. |
GEO_PRIDE_ACCESS_NO | GSE2475 |
REFERENCE | 18922145 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:8
ACCESS NO | 100347 |
GENE | DYSF |
DESCRIPTION | Dysferlin |
NCBI ENTREZ ACCESS NO | 8291 |
UNIPROT ACCESS NO | O75923 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | It is upregulated in asthma exacerbation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19187333 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Dysferlin for Mouse/Human |
Record No:9
ACCESS NO | 100366 |
GENE | Dpysl2 |
DESCRIPTION | Dihydropyrimidinase-related protein 2 |
NCBI ENTREZ ACCESS NO | 12934 |
UNIPROT ACCESS NO | O08553 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Allergen induced asthma and Dexamethasone treatment |
SAMPLE | Broncho Alveolar Lavage (BAL) |
TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein contributes to free radical-mediated protein modification in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15378748 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-CRMP2 for Human/Rat/Mouse |
Record No:10
ACCESS NO | 100483 |
GENE | DSC1 |
DESCRIPTION | Desmocollin-1 |
NCBI ENTREZ ACCESS NO | 1823 |
UNIPROT ACCESS NO | Q08554 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis and eczema |
SAMPLE | Skin tapings |
TECHNIQUES | nano-HPLC-MS/MS (ion trap) |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. It is a component of corneodesmosome. Corneodesmosomes bind keratins to the cellular membrane and serve to tightly attach adjacent corneocytes. Thus it acts as a skin barrier. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21211653 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Desmocollin 3 for Human |
Record No:11
ACCESS NO | 100484 |
GENE | DSG1 |
DESCRIPTION | Desmoglein-1 |
NCBI ENTREZ ACCESS NO | 1828 |
UNIPROT ACCESS NO | Q02413 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis and eczema |
SAMPLE | Skin tapings |
TECHNIQUES | nano-HPLC-MS/MS (ion trap) |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient without eczema herpeticum. This protein is related to the skin barrier. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21211653 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Desmoglein 1 for Mouse/Rat/Human |
Record No:12
ACCESS NO | 100492 |
GENE | DPYSL5 |
DESCRIPTION | Dihydropyrimidinase-like 5 |
NCBI ENTREZ ACCESS NO | 56896 |
UNIPROT ACCESS NO | Q9BPU6 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of glucocorticoid treatment |
SAMPLE | Bronchial biopsy |
TECHNIQUES | iTRAQ labelling followed by nano LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It plays a role in growth and guidance. It is upregulated after budesonide treatment. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21939520 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-CRMP5 [CR-3] for Mouse/Rat/Human |
Record No:13
ACCESS NO | 100497 |
GENE | DPT |
DESCRIPTION | Dermatopontin |
NCBI ENTREZ ACCESS NO | 1805 |
UNIPROT ACCESS NO | Q07507 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of glucocorticoid treatment |
SAMPLE | Bronchial biopsy |
TECHNIQUES | iTRAQ labelling followed by nano LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is involved in collagen fibrillogenesis. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21939520 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:14
ACCESS NO | 100568 |
GENE | DYNC2LI1 |
DESCRIPTION | Dynein |
NCBI ENTREZ ACCESS NO | 51626 |
UNIPROT ACCESS NO | Q8TCX1 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | CD3+T cell |
TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | A microtubule dependant motor protein which gets downregulated in asthamtic patients. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17550934 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:15
ACCESS NO | 100605 |
GENE | DSP |
DESCRIPTION | Desmoplakin I |
NCBI ENTREZ ACCESS NO | 1832 |
UNIPROT ACCESS NO | P15924 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Broncho Alveolar Lavage (BAL)F |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It is a cytoskeletal protein and is upregulated after allergen challenge. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Desmoplkin I+II for Human/Mouse/Rat |
Record No:16
ACCESS NO | 100778 |
GENE | DPP10 |
DESCRIPTION | Dipeptidyl-peptidase 10 |
NCBI ENTREZ ACCESS NO | 57628 |
UNIPROT ACCESS NO | Q8N608 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | DNA |
TECHNIQUES | Illumina Human Hap 550Kv3 BeadChip SNP array |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | rs1914973 SNP is associated with asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19264973 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-DPP10 for Human |
Record No:17
ACCESS NO | 100843 |
GENE | Dhfr |
DESCRIPTION | Dihydrofolate reductase |
NCBI ENTREZ ACCESS NO | 13361 |
UNIPROT ACCESS NO | P00375 |
ORGANISM | SWR/J mouse |
DISEASE PHENOTYPE | Allergic conjunctivitis |
SAMPLE | Conjunctival Tissues |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | A key enzyme in the folate metabolism and involved in purine synthesis. Highly expressed in conjuctiva of allergic mouse. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18658092 |
DRUG TARGET | BE0000330 |
MONCLONAL ANTIBODY | Anti-Dihydrofolate reductase for Mouse/Rat/Human |
Record No:18
ACCESS NO | 101007 |
GENE | DEFB1 |
DESCRIPTION | beta-defensin 1 |
NCBI ENTREZ ACCESS NO | 1672 |
UNIPROT ACCESS NO | P60022 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
SAMPLE | Sputum |
TECHNIQUES | Microarray and qPCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It shows highest expression in patients with paucigranulocytic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24582314 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:19
ACCESS NO | 101008 |
GENE | DNASE1L3 |
DESCRIPTION | Deoxyribonuclease I-like 3 |
NCBI ENTREZ ACCESS NO | 1776 |
UNIPROT ACCESS NO | Q13609 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
SAMPLE | Sputum |
TECHNIQUES | Microarray and qPCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It shows highest expression in patients with eosinophilic asthma. Its expression decresed after inhaled corticosteroid treatment. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24582314 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-DNase gamma for Mouse/Rat/Human |
Record No:20
ACCESS NO | 101031 |
GENE | DSP |
DESCRIPTION | Desmoplakin |
NCBI ENTREZ ACCESS NO | 1832 |
UNIPROT ACCESS NO | P15924 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic eczema (AE) |
SAMPLE | Vernix |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is strongly upregulated in atopic eczema. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24205894 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Desmoplakin I+II for Mouse/Rat/Human |
Record No:21
ACCESS NO | 101143 |
GENE | DUSP1 (MKP-1) |
DESCRIPTION | Mitogen-activated protein kinase phosphatase 1 |
NCBI ENTREZ ACCESS NO | 1843 |
UNIPROT ACCESS NO | P28562 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | real-time PCR |
OMICS | Genomics |
STUDY | Low Throughput |
COMMENTS | In vitro glucocorticoid insensitivity in obese asthmatics is represented by a reduced ability of dexamethasone to induce the expression of MKP-1 (an anti-inflammatory marker of GC-induced transactivation) appears to be mediated by reduced expression of GCRα. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 22606276 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:22
ACCESS NO | 101202 |
GENE | DCAF7 |
DESCRIPTION | DDB1- and CUL4-associated factor 7 |
NCBI ENTREZ ACCESS NO | 10238 |
UNIPROT ACCESS NO | P61962 |
ORGANISM | Human |
DISEASE PHENOTYPE | Food allergy |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 22091390 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-WDR68 for Mouse/Rat/Human |
Record No:23
ACCESS NO | 101203 |
GENE | DRG1 |
DESCRIPTION | Developmentally regulated GTP-binding protein 1 |
NCBI ENTREZ ACCESS NO | 4733 |
UNIPROT ACCESS NO | Q9Y295 |
ORGANISM | Human |
DISEASE PHENOTYPE | Food allergy |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein was found to be upregulated in RAST+ subjects with severe food allergies. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 22091390 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-DRG1 for Mouse/Rat/Human |
Record No:24
ACCESS NO | 101204 |
GENE | DNAJC27 |
DESCRIPTION | DnaJ homolog subfamily C member 27 |
NCBI ENTREZ ACCESS NO | 51277 |
UNIPROT ACCESS NO | Q9NZQ0 |
ORGANISM | Human |
DISEASE PHENOTYPE | Food allergy |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 22091390 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-RBJ for Human |
Record No:25
ACCESS NO | 101270 |
GENE | DCD |
DESCRIPTION | Dermcidin |
NCBI ENTREZ ACCESS NO | 117159 |
UNIPROT ACCESS NO | P81605 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Exhaled Breath condensate |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Present in exhaled blood condensate of asthma patients. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21105917 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:26
ACCESS NO | 101493 |
GENE | Dusp2 |
DESCRIPTION | Dual specificity phosphatase 2 |
NCBI ENTREZ ACCESS NO | 13537 |
UNIPROT ACCESS NO | Q05922 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:27
ACCESS NO | 101516 |
GENE | Darc |
DESCRIPTION | Atypical chemokine receptor 1 |
NCBI ENTREZ ACCESS NO | 13349 |
UNIPROT ACCESS NO | Q9QUI6 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-DARC mouse/Human |
Record No:28
ACCESS NO | 101808 |
GENE | DSP |
DESCRIPTION | Desmoplakin I |
NCBI ENTREZ ACCESS NO | 1832 |
UNIPROT ACCESS NO | P15924 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This cytoskeletal protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Desmoplakin I+II [2Q400] for Mouse/Rat/Human |
Record No:29
ACCESS NO | 101820 |
GENE | DYNLRB1 |
DESCRIPTION | Dynein light chain 2A |
NCBI ENTREZ ACCESS NO | 83658 |
UNIPROT ACCESS NO | Q9NP97 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:30
ACCESS NO | 101872 |
GENE | DPYSL2 |
DESCRIPTION | Dihydropyrimidinase related protein-2 |
NCBI ENTREZ ACCESS NO | 1808 |
UNIPROT ACCESS NO | Q16555 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Fibroblast |
TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is upregulated in atopic fibroblasts comparative to normal fibroblasts. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15468290 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-CRMP2 for Mouse/Rat/Human |
Record No:31
ACCESS NO | 101892 |
GENE | DDX41 |
DESCRIPTION | DEAD-box protein 41 |
NCBI ENTREZ ACCESS NO | 51428 |
UNIPROT ACCESS NO | Q9UJV9 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Fibroblast |
TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is down regulated in atopic fibroblasts comparative to normal fibroblasts. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15468290 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-DDX41 for Mouse/Rat/Human |
Record No:32
ACCESS NO | 101906 |
GENE | DUSP10 |
DESCRIPTION | Mitogen-activated protein kinase phosphatase 5 |
NCBI ENTREZ ACCESS NO | 11221 |
UNIPROT ACCESS NO | Q9Y6W6 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Peripheral blood eosinophils |
TECHNIQUES | 2DE-PAGE and MALDI-TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15832365 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-DUSP10 for Mouse/Rat/Human |
Record No:33
ACCESS NO | 101944 |
GENE | DYSF |
DESCRIPTION | Dysferlin limb girdle muscular dystrophy 2B |
NCBI ENTREZ ACCESS NO | 8291 |
UNIPROT ACCESS NO | O75923 |
ORGANISM | Human(Asthmatic children) |
DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
SAMPLE | Peripheral Blood Mononuclear Cells |
TECHNIQUES | Microarray and RT-PCR |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19187333 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Dysferlin for Mouse/Human |
Record No:34
ACCESS NO | 102017 |
GENE | DUSP1 |
DESCRIPTION | Dual specificity phosphatase 1 |
NCBI ENTREZ ACCESS NO | 1843 |
UNIPROT ACCESS NO | P28562 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis and asthma |
SAMPLE | Primary nasal and bronchial epithelial cells |
TECHNIQUES | Microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Dowregulated in upper airways(data in suplimentary table). |
GEO_PRIDE_ACCESS_NO | GSE44037 |
REFERENCE | 24282527 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:35
ACCESS NO | 102028 |
GENE | DPYSL3 |
DESCRIPTION | Dihydropyrimidinase-like 3 |
NCBI ENTREZ ACCESS NO | 1809 |
UNIPROT ACCESS NO | Q14195 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis and asthma |
SAMPLE | Bronchial epithelial cells |
TECHNIQUES | Microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Highly expressed in patients with allergic rhinitis and asthma.(Data in supplimentary table). |
GEO_PRIDE_ACCESS_NO | GSE44037 |
REFERENCE | 24282527 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-CRMP4 for Mouse/Rat/Human |
Record No:36
ACCESS NO | 102103 |
GENE | DPP4 |
DESCRIPTION | Dipeptidyl-peptidase 4 |
NCBI ENTREZ ACCESS NO | 1803 |
UNIPROT ACCESS NO | P27487 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic asthma |
SAMPLE | CD4+ T cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated in Asthma. Involved in TCR signalling and expressed in TH2 cells. |
GEO_PRIDE_ACCESS_NO | GSE14908 |
REFERENCE | 19414752 |
DRUG TARGET | BE0000854 |
MONCLONAL ANTIBODY | Anti-CD26 for Mouse/Rat/Human |
Record No:37
ACCESS NO | 102129 |
GENE | DACT1 |
DESCRIPTION | Dapper homolog 1 |
NCBI ENTREZ ACCESS NO | 51339 |
UNIPROT ACCESS NO | Q9NYF0 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic asthma |
SAMPLE | CD4+ T cells |
TECHNIQUES | Microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Upregulated in asthma.Regulates beta catenin. |
GEO_PRIDE_ACCESS_NO | GSE14908 |
REFERENCE | 19414752 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |