BROWSE RESULT OF G
| 72 Records |
| ACCESS NO | 100114 |
| GENE | Gatm |
| DESCRIPTION | Glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| NCBI ENTREZ ACCESS NO | 67092 |
| UNIPROT ACCESS NO | Q9D964 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an IL-4 specific arginine metabolism gene induced in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | BE0000347 |
| MONCLONAL ANTIBODY | Anti-GATM for Human |
Record No:2
| ACCESS NO | 100116 |
| GENE | Gbp4 |
| DESCRIPTION | Guanylate nucleotide binding protein 4 |
| NCBI ENTREZ ACCESS NO | 17472 |
| UNIPROT ACCESS NO | A4UUI3 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This intracellular signaling protein is an asthma signature gene highly induced by Th2 cytokines such as IL-4 and IL-13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:3
| ACCESS NO | 100177 |
| GENE | GPR98 (MASS1) |
| DESCRIPTION | Monogenic audiogenic seizure susceptibility 1 homolog |
| NCBI ENTREZ ACCESS NO | 84059 |
| UNIPROT ACCESS NO | Q8WXG9 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:4
| ACCESS NO | 100277 |
| GENE | GAS6 |
| DESCRIPTION | Growth arrest-specific 6 |
| NCBI ENTREZ ACCESS NO | 2621 |
| UNIPROT ACCESS NO | Q14393 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays and real time |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is an infection related gene upregulated in asthma exacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GAS for Mouse |
Record No:5
| ACCESS NO | 100291 |
| GENE | Gadd45a |
| DESCRIPTION | Growth arrest and DNA-damage-inducible protein |
| NCBI ENTREZ ACCESS NO | 13197 |
| UNIPROT ACCESS NO | P48316 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | A transcription factor named Foxo4 binds to its promoter and modulate its transcription to influence G2/M cell cycle arrest during stress response of asthmatic damage. It is down regulated in the present study. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GADD45A for Human |
Record No:6
| ACCESS NO | 100333 |
| GENE | Gc |
| DESCRIPTION | Vitamin D binding protein (DBP) or Globulin |
| NCBI ENTREZ ACCESS NO | 14473 |
| UNIPROT ACCESS NO | P21614 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced chemicals |
| SAMPLE | Broncho Alveolar Lavage (BAL) |
| TECHNIQUES | 2D DIGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | DBP interacts with neutrophils to enhance the chemotactic activity of complement derived C5 peptides. Neutrophils are significantly increased in the BAL fluid of TDI-treated mice and also the complement system is known to be associated with the pathogenesis of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20860378 |
| DRUG TARGET | BE0001141 |
| MONCLONAL ANTIBODY | N/A |
Record No:7
| ACCESS NO | 100342 |
| GENE | Gsn |
| DESCRIPTION | Gelsolin |
| NCBI ENTREZ ACCESS NO | 227753 |
| UNIPROT ACCESS NO | P13020 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced chemicals |
| SAMPLE | Serum |
| TECHNIQUES | 2D DIGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved In inflammatory response. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20860378 |
| DRUG TARGET | BE0004161 |
| MONCLONAL ANTIBODY | Anti-Gelsolin for Human |
Record No:8
| ACCESS NO | 100354 |
| GENE | GRINA |
| DESCRIPTION | Glutamate receptor-ionotropic-N-methyl-d-asparate-associated protein 1 |
| NCBI ENTREZ ACCESS NO | 2907 |
| UNIPROT ACCESS NO | Q7Z429 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is upregulated in asthma exacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:9
| ACCESS NO | 100360 |
| GENE | Gnai2 |
| DESCRIPTION | Guanine nucleotide binding protein alpha-inhibiting 2 |
| NCBI ENTREZ ACCESS NO | 81664 |
| UNIPROT ACCESS NO | P04897 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in the regulation of tight junction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18922145 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-G protein alpha Inhibitor 2 for Mouse/Rat/Human |
Record No:10
| ACCESS NO | 100370 |
| GENE | Gm5506 |
| DESCRIPTION | Alpha enolase |
| NCBI ENTREZ ACCESS NO | 433182 |
| UNIPROT ACCESS NO | P17182 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergen induced asthma and Dexamethasone treatment |
| SAMPLE | Broncho Alveolar Lavage (BAL) |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This gene is responsible for free radical-mediated protein modification in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15378748 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:11
| ACCESS NO | 100426 |
| GENE | G3BP1 |
| DESCRIPTION | Ras-GTPase-activating protein SH3-domain-binding protein |
| NCBI ENTREZ ACCESS NO | 10146 |
| UNIPROT ACCESS NO | Q13283 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | bronchial epithelial cells stimulated with TGF bet |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It stimulates the pathway for cell proliferation and growth regulation. It is essential because it regulates the stability or translational efficiency of newly synthesized mRNA. It also acts as a negative regulator of p53 and may thereby be involved in the regulation of apoptosis of bronchial epithelial cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20219718 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-G3BP for Human |
Record No:12
| ACCESS NO | 100456 |
| GENE | GSN |
| DESCRIPTION | Gelsolin |
| NCBI ENTREZ ACCESS NO | 2934 |
| UNIPROT ACCESS NO | P06396 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Respiratory Allergy |
| SAMPLE | Nasal Epithelial Cell |
| TECHNIQUES | Affymetrix microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene is upregulated upon dust mite allergen challenge. |
| GEO_PRIDE_ACCESS_NO | GSE19190 |
| REFERENCE | 22005912 |
| DRUG TARGET | BE0004161 |
| MONCLONAL ANTIBODY | Anti-Gelsolin for Mouse/Human |
Record No:13
| ACCESS NO | 100459 |
| GENE | GCNT3 |
| DESCRIPTION | Glucosaminyl (N-acetyl) transferase 3 mucin type |
| NCBI ENTREZ ACCESS NO | 9245 |
| UNIPROT ACCESS NO | O95395 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Respiratory Allergy |
| SAMPLE | Nasal Epithelial Cell |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated upon dust mite allergen challenge. |
| GEO_PRIDE_ACCESS_NO | GSE19190 |
| REFERENCE | 22005912 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:14
| ACCESS NO | 100461 |
| GENE | GCNT4 |
| DESCRIPTION | Glucosaminyl (N-acetyl) transferase 4-core 2 |
| NCBI ENTREZ ACCESS NO | 51301 |
| UNIPROT ACCESS NO | Q9P109 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Respiratory Allergy |
| SAMPLE | Nasal Epithelial Cell |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated significantly upon Il-4 and IL-13 challenge. |
| GEO_PRIDE_ACCESS_NO | GSE19190 |
| REFERENCE | 22005912 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:15
| ACCESS NO | 100486 |
| GENE | GGCT |
| DESCRIPTION | Gamma-glutamylcyclotransferase |
| NCBI ENTREZ ACCESS NO | 79017 |
| UNIPROT ACCESS NO | O75223 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis and eczema |
| SAMPLE | Skin tapings |
| TECHNIQUES | nano-HPLC-MS/MS (ion trap) |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It catalyzes the formation of pyroglutamic acid or PCA which is the most abundant cnstituent of natural moisturizing factor in the stratum corneum. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211653 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:16
| ACCESS NO | 100556 |
| GENE | Gnb2 |
| DESCRIPTION | Guanine nucleotide binding protein-beta polypeptide 2 |
| NCBI ENTREZ ACCESS NO | 14693 |
| UNIPROT ACCESS NO | P62880 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Tissue from bronchial biopsy |
| TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Intracellular signaling molecule (data collected from supplementary table) |
| GEO_PRIDE_ACCESS_NO | GSE15823 |
| REFERENCE | 15038835 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GNB2 for Human/Mouse/Rat |
Record No:17
| ACCESS NO | 100562 |
| GENE | Gas1 |
| DESCRIPTION | Growth arrest-specific protein 1 |
| NCBI ENTREZ ACCESS NO | 14451 |
| UNIPROT ACCESS NO | Q01721 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Tissue from bronchial biopsy |
| TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in cell growth and proliferation(data collected from supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE15823 |
| REFERENCE | 15038835 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GAS1 for Human |
Record No:18
| ACCESS NO | 100655 |
| GENE | GSN |
| DESCRIPTION | Gelsolin |
| NCBI ENTREZ ACCESS NO | 2934 |
| UNIPROT ACCESS NO | P06396 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma proteins |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in coagulation cascade. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21471098 |
| DRUG TARGET | BE0004161 |
| MONCLONAL ANTIBODY | Anti-Gelsolin for Human |
Record No:19
| ACCESS NO | 100664 |
| GENE | Grp78 |
| DESCRIPTION | 78Kda glucose regulated protein precursor |
| NCBI ENTREZ ACCESS NO | 14828 |
| UNIPROT ACCESS NO | P20029 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof and Western Blotting |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Belongs to chaperone protein family and is involved in stress induced cellular damage after allergen exposure. Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | BE0001098 |
| MONCLONAL ANTIBODY | Anti-GRP78 BiP for Mouse/Rat/Human |
Record No:20
| ACCESS NO | 100690 |
| GENE | Gstm2 |
| DESCRIPTION | Glutathione S-transferase Mu 2 |
| NCBI ENTREZ ACCESS NO | 14863 |
| UNIPROT ACCESS NO | P15626 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergen induced asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | BE0001189 |
| MONCLONAL ANTIBODY | Anti-GSTM2 for Mouse/Human |
Record No:21
| ACCESS NO | 100705 |
| GENE | GP-39 |
| DESCRIPTION | Chi3l1 |
| NCBI ENTREZ ACCESS NO | 12654 |
| UNIPROT ACCESS NO | Q61362 |
| ORGANISM | TSLP TG mice and BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid Broncho Alveol |
| TECHNIQUES | LC-MS/MS and Western blot and qRT PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Significantly lowered after Dexamethasone treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22837640 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CHI3L1 for Human |
Record No:22
| ACCESS NO | 100782 |
| GENE | GPR154 |
| DESCRIPTION | Neuropeptide S receptor 1 |
| NCBI ENTREZ ACCESS NO | 387129 |
| UNIPROT ACCESS NO | Q6W5P4 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | DNA |
| TECHNIQUES | Illumina Human Hap 550Kv3 BeadChip SNP array |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | rs17789834 SNP is associated with asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19264973 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-NPSR1 for Human |
Record No:23
| ACCESS NO | 100841 |
| GENE | Gp49b |
| DESCRIPTION | Glycoprotein 49B |
| NCBI ENTREZ ACCESS NO | 14728 |
| UNIPROT ACCESS NO | Q64281 |
| ORGANISM | SWR/J mouse |
| DISEASE PHENOTYPE | Allergic conjunctivitis |
| SAMPLE | Conjunctival Tissues |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Expressed mainly on the mast cell and plays a major role in its regulation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18658092 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:24
| ACCESS NO | 100931 |
| GENE | Gas1 |
| DESCRIPTION | Growth arrest specific 1 |
| NCBI ENTREZ ACCESS NO | 14451 |
| UNIPROT ACCESS NO | Q01721 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after induction with food allergens. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Gas1 for Human |
Record No:25
| ACCESS NO | 100943 |
| GENE | Gpc1 |
| DESCRIPTION | Glypican 1 |
| NCBI ENTREZ ACCESS NO | 14733 |
| UNIPROT ACCESS NO | Q9QZF2 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after induction with food allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:26
| ACCESS NO | 101034 |
| GENE | GDPD3 |
| DESCRIPTION | Glycerophosphodiester phosphodiesterase domain-containing protein 3 |
| NCBI ENTREZ ACCESS NO | 79153 |
| UNIPROT ACCESS NO | Q7L5L3 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly upregulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:27
| ACCESS NO | 101036 |
| GENE | GM2A |
| DESCRIPTION | Ganglioside GM2 activator |
| NCBI ENTREZ ACCESS NO | 2760 |
| UNIPROT ACCESS NO | P17900 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly upregulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | BE0001432 |
| MONCLONAL ANTIBODY | N/A |
Record No:28
| ACCESS NO | 101046 |
| GENE | GOT1 |
| DESCRIPTION | Aspartate aminotransferase. cytoplasmic |
| NCBI ENTREZ ACCESS NO | 2805 |
| UNIPROT ACCESS NO | P17174 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly down regulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | BE0000529 |
| MONCLONAL ANTIBODY | N/A |
Record No:29
| ACCESS NO | 101162 |
| GENE | GPX1 |
| DESCRIPTION | Glutathione peroxidase 1 |
| NCBI ENTREZ ACCESS NO | 2876 |
| UNIPROT ACCESS NO | P07203 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
| SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
| TECHNIQUES | 2D-DIGE and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene is over expressed after dexamethasone treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22464673 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Glutathione Peroxidase 1 [EPR3312] for Mouse/Rat/Human |
Record No:30
| ACCESS NO | 101219 |
| GENE | GDI1 |
| DESCRIPTION | Rab GDP dissociation inhibitor alpha |
| NCBI ENTREZ ACCESS NO | 2664 |
| UNIPROT ACCESS NO | P31150 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | BE0004511 |
| MONCLONAL ANTIBODY | Anti-GDI1 [EPR13195] for Mouse/Rat/Human |
Record No:31
| ACCESS NO | 101221 |
| GENE | GHRH |
| DESCRIPTION | Somatoliberin |
| NCBI ENTREZ ACCESS NO | 2691 |
| UNIPROT ACCESS NO | P01286 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:32
| ACCESS NO | 101318 |
| GENE | GNAI2 |
| DESCRIPTION | GTP-binding regulatory protein Gi alpha-2 chain |
| NCBI ENTREZ ACCESS NO | 2771 |
| UNIPROT ACCESS NO | P04899 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy(Comparison of Dendritic cell proteome in atopic and non atopic patients) |
| SAMPLE | Dendritic cell |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Knockout leads to Th1 signalling. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19494521 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-G protein alpha Inhibitor 2 for Mouse/Rat/Human |
Record No:33
| ACCESS NO | 101370 |
| GENE | Gpx3 |
| DESCRIPTION | Glutathione peroxidase 3 precursor |
| NCBI ENTREZ ACCESS NO | 14778 |
| UNIPROT ACCESS NO | P46412 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in cellular metabolism and expressed in chronic asthma mouse model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | BE0000821 |
| MONCLONAL ANTIBODY | Anti-Glutathione Peroxidase 3 for Mouse/Rat/Human |
Record No:34
| ACCESS NO | 101391 |
| GENE | Gob-5 |
| DESCRIPTION | Gob-5 protein |
| NCBI ENTREZ ACCESS NO | 23844 |
| UNIPROT ACCESS NO | Q9D7Z6 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Elevated in chronically inflammed lungs. Controls Chloride channel activity for mucus production. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CLCA1 for Human |
Record No:35
| ACCESS NO | 101404 |
| GENE | Gpr84 |
| DESCRIPTION | G protein-coupled receptor 84 |
| NCBI ENTREZ ACCESS NO | 80910 |
| UNIPROT ACCESS NO | Q8CIM5 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:36
| ACCESS NO | 101412 |
| GENE | Gpr109a |
| DESCRIPTION | Hydroxycarboxylic acid receptor 2 |
| NCBI ENTREZ ACCESS NO | 80885 |
| UNIPROT ACCESS NO | Q9EP66 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0000635 |
| MONCLONAL ANTIBODY | Anti-Puma gamma for Human |
Record No:37
| ACCESS NO | 101513 |
| GENE | Gadd45g |
| DESCRIPTION | Growth arrest and DNA-damage-inducible 45 gamma |
| NCBI ENTREZ ACCESS NO | 23882 |
| UNIPROT ACCESS NO | Q9R0S0 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GADD45G for Human |
Record No:38
| ACCESS NO | 101542 |
| GENE | Gsk-3b |
| DESCRIPTION | Glycogen Synthase Kinase-3b |
| NCBI ENTREZ ACCESS NO | 56637 |
| UNIPROT ACCESS NO | Q9WV60 |
| ORGANISM | Female Balb/c Mice |
| DISEASE PHENOTYPE | Asthma(Effect of Glycogen synthase kinase-3 beta inhibition on asthma) |
| SAMPLE | Bronchial epithelial cell lysate |
| TECHNIQUES | Western blotting |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | A regulator Nf kappa beta which involved in asthma pathogenesis. Inhibition of Gsk-3b decreases asthma excacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17556716 |
| DRUG TARGET | BE0001065 |
| MONCLONAL ANTIBODY | Anti-GSK3 beta for Mouse/Human |
Record No:39
| ACCESS NO | 101576 |
| GENE | Guca2a |
| DESCRIPTION | Guanylate cyclase activator 2a |
| NCBI ENTREZ ACCESS NO | 14915 |
| UNIPROT ACCESS NO | P33680 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in ion flux and expressed after IL 13 treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:40
| ACCESS NO | 101582 |
| GENE | Gsto1 |
| DESCRIPTION | Glutathione S-transferase omega 1 |
| NCBI ENTREZ ACCESS NO | 14873 |
| UNIPROT ACCESS NO | O09131 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in Redox reactions and expressed after induction with IL 13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | BE0000815 |
| MONCLONAL ANTIBODY | Anti-glutathione S transferase Omega 1 for Mouse/Rat/Human |
Record No:41
| ACCESS NO | 101583 |
| GENE | Gclc |
| DESCRIPTION | Glutamate-cysteine ligase catalytic subunit |
| NCBI ENTREZ ACCESS NO | 14629 |
| UNIPROT ACCESS NO | P97494 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in Redox reactions and expressed after induction with IL 13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | BE0000166 |
| MONCLONAL ANTIBODY | Anti-GCLC for Rat/Human |
Record No:42
| ACCESS NO | 101584 |
| GENE | Glrx1 |
| DESCRIPTION | Glutaredoxin |
| NCBI ENTREZ ACCESS NO | 93692 |
| UNIPROT ACCESS NO | Q9QUH0 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in Redox reactions and expressed after induction with IL 13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Glutaredoxin 1 for Human |
Record No:43
| ACCESS NO | 101621 |
| GENE | Gadd45g |
| DESCRIPTION | Growth arrest and DNA-damage-inducible 45 gamma |
| NCBI ENTREZ ACCESS NO | 23882 |
| UNIPROT ACCESS NO | Q9R0S0 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GADD45G for Human |
Record No:44
| ACCESS NO | 101673 |
| GENE | Gata3 (GATA-3) |
| DESCRIPTION | GATA binding protein 3 |
| NCBI ENTREZ ACCESS NO | 14462 |
| UNIPROT ACCESS NO | P23772 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and its modulation by Minocycline |
| SAMPLE | CD3/CD28-stimulated CD4+ T cells |
| TECHNIQUES | Real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Minocycline marked reduction in the expression of this NF kappa Beta dependent gene. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23184953 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GATA3 for Human |
Record No:45
| ACCESS NO | 101691 |
| GENE | Grp |
| DESCRIPTION | Gastrin-releasing peptide |
| NCBI ENTREZ ACCESS NO | 225642 |
| UNIPROT ACCESS NO | Q8R1I2 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Whole lung |
| TECHNIQUES | qRT-PCR and immunochemistry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is a pro-inflammatory peptide by pulmonary neuroendocrine cells in asthmatic lung. Treatment with blocking agent 77427 and blocking antiobody 2A11 abrogates the airway hyper responsiveness and inflammation. Targated blockade of this gene is even better effective than dexamethasone therapy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21252304 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Grp75 [JG1] for Mouse/Rat/Human |
Record No:46
| ACCESS NO | 101706 |
| GENE | GPLD1 |
| DESCRIPTION | Glycosylphosphatidylinositol phospholipase D |
| NCBI ENTREZ ACCESS NO | 2822 |
| UNIPROT ACCESS NO | P80108 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This granule protein is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GPLD1 for Human |
Record No:47
| ACCESS NO | 101739 |
| GENE | GAPDH |
| DESCRIPTION | Uracil-DNA glycosylase |
| NCBI ENTREZ ACCESS NO | 2597 |
| UNIPROT ACCESS NO | Q5ZEY3 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000542 |
| MONCLONAL ANTIBODY | Anti-GAPDH [6C5] for Mouse/Rat/Human |
Record No:48
| ACCESS NO | 101744 |
| GENE | GSR |
| DESCRIPTION | Glutathione reductase mitochondrial (GR) (GRase) |
| NCBI ENTREZ ACCESS NO | 2936 |
| UNIPROT ACCESS NO | E5RI06 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000648 |
| MONCLONAL ANTIBODY | Anti-Glutathione Reductase for Human |
Record No:49
| ACCESS NO | 101748 |
| GENE | GPX3 |
| DESCRIPTION | Glutathione peroxidase |
| NCBI ENTREZ ACCESS NO | 2878 |
| UNIPROT ACCESS NO | Q6NXQ3 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000821 |
| MONCLONAL ANTIBODY | Anti-Glutathione Peroxidase 3 [23B1] for Mouse/Human |
Record No:50
| ACCESS NO | 101750 |
| GENE | GPX4 |
| DESCRIPTION | Glutathione peroxidase 4 |
| NCBI ENTREZ ACCESS NO | 2879 |
| UNIPROT ACCESS NO | Q6PJX4 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0001135 |
| MONCLONAL ANTIBODY | Anti-Glutathione Peroxidase 4 [EPNCIR144] for Mouse/Rat/Human |
Record No:51
| ACCESS NO | 101790 |
| GENE | GC |
| DESCRIPTION | Vitamin D-binding protein/group-specific component |
| NCBI ENTREZ ACCESS NO | 2638 |
| UNIPROT ACCESS NO | D6RF35 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This serum protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0001141 |
| MONCLONAL ANTIBODY | Anti-GC1q R [60.11] for Mouse/Rat/Human |
Record No:52
| ACCESS NO | 101819 |
| GENE | GNB2L1 |
| DESCRIPTION | Guanine nucleotide-binding protein beta subunit-like |
| NCBI ENTREZ ACCESS NO | 10399 |
| UNIPROT ACCESS NO | P63244 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:53
| ACCESS NO | 101827 |
| GENE | GPR116 |
| DESCRIPTION | G-protein-coupled receptor GPR116 |
| NCBI ENTREZ ACCESS NO | 221395 |
| UNIPROT ACCESS NO | Q8IZF2 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is down regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:54
| ACCESS NO | 101855 |
| GENE | GDF15 |
| DESCRIPTION | Prostate differentiation factor |
| NCBI ENTREZ ACCESS NO | 9518 |
| UNIPROT ACCESS NO | Q99988 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic Rhinitis induced by pollen allergen |
| SAMPLE | Nasal lavage fluids |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This anti inflammatory gene showed lower expression levels in patients than in controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15836756 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GDF15 [6D12.H10.E4] for Mouse/Human |
Record No:55
| ACCESS NO | 101857 |
| GENE | GSTA4 |
| DESCRIPTION | Glutathione S-transferase (GST) A4 |
| NCBI ENTREZ ACCESS NO | 2941 |
| UNIPROT ACCESS NO | O15217 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic Rhinitis induced by pollen allergen |
| SAMPLE | Nasal lavage fluids |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This anti inflammatory gene showed lower expression levels in patients than in controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15836756 |
| DRUG TARGET | BE0000811 |
| MONCLONAL ANTIBODY | Anti-GSTA4 for Rat/Human |
Record No:56
| ACCESS NO | 101858 |
| GENE | GSTA2 |
| DESCRIPTION | Glutathione S-transferase alpha 2 |
| NCBI ENTREZ ACCESS NO | 2939 |
| UNIPROT ACCESS NO | P09210 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic Rhinitis induced by pollen allergen |
| SAMPLE | Nasal lavage fluids |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This anti inflammatory gene showed lower expression levels in patients than in controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15836756 |
| DRUG TARGET | BE0002189 |
| MONCLONAL ANTIBODY | Anti-GSTA2 for Human |
Record No:57
| ACCESS NO | 101859 |
| GENE | GSTZ1 (GST-z 1) |
| DESCRIPTION | Glutathione S-transferase zeta 1 |
| NCBI ENTREZ ACCESS NO | 2954 |
| UNIPROT ACCESS NO | O43708 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic Rhinitis induced by pollen allergen |
| SAMPLE | Nasal lavage fluids |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This anti inflammatory gene showed lower expression levels in patients than in controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15836756 |
| DRUG TARGET | BE0000819 |
| MONCLONAL ANTIBODY | N/A |
Record No:58
| ACCESS NO | 101860 |
| GENE | GSTP1 (GST-p1) |
| DESCRIPTION | Glutathione S-transferase pi 1 |
| NCBI ENTREZ ACCESS NO | 2950 |
| UNIPROT ACCESS NO | P09211 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic Rhinitis induced by pollen allergen |
| SAMPLE | Nasal lavage fluids |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This anti inflammatory gene showed lower expression levels in patients than in controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15836756 |
| DRUG TARGET | BE0000814 |
| MONCLONAL ANTIBODY | N/A |
Record No:59
| ACCESS NO | 101861 |
| GENE | GSTM1 |
| DESCRIPTION | GST subunit 4 |
| NCBI ENTREZ ACCESS NO | 2944 |
| UNIPROT ACCESS NO | P09488 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic Rhinitis induced by pollen allergen |
| SAMPLE | Nasal lavage fluids |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This anti inflammatory gene showed lower expression levels in patients than in controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15836756 |
| DRUG TARGET | BE0000807 |
| MONCLONAL ANTIBODY | Anti-GSTM1/2/4/5 for Mouse/Rat/Human |
Record No:60
| ACCESS NO | 101886 |
| GENE | GOLGA1 |
| DESCRIPTION | Golgi autoantigen |
| NCBI ENTREZ ACCESS NO | 2800 |
| UNIPROT ACCESS NO | Q92805 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Fibroblast |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic fibroblasts comparative to normal fibroblasts. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15468290 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:61
| ACCESS NO | 101897 |
| GENE | GRIA2 |
| DESCRIPTION | Glutamate receptor 2 |
| NCBI ENTREZ ACCESS NO | 2891 |
| UNIPROT ACCESS NO | P42262 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | BE0000829 |
| MONCLONAL ANTIBODY | Anti-Ionotropic Glutamate receptor 2 for Mouse/Rat/Human |
Record No:62
| ACCESS NO | 101902 |
| GENE | GNAQ |
| DESCRIPTION | G protein-coupled receptor kinase 2 |
| NCBI ENTREZ ACCESS NO | 2776 |
| UNIPROT ACCESS NO | P50148 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:63
| ACCESS NO | 101910 |
| GENE | GRB7 |
| DESCRIPTION | Grb7 adaptor protein |
| NCBI ENTREZ ACCESS NO | 2886 |
| UNIPROT ACCESS NO | Q14451 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF and Immunoblot |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This protein is upregulated in healthy donors eosinophils. It is present in tyrosine phosphorylated form. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GRB7 for Mouse/Rat/Human |
Record No:64
| ACCESS NO | 101928 |
| GENE | GPT |
| DESCRIPTION | Alanine aminotransferase |
| NCBI ENTREZ ACCESS NO | 2875 |
| UNIPROT ACCESS NO | P24298 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | BE0000667 |
| MONCLONAL ANTIBODY | N/A |
Record No:65
| ACCESS NO | 101929 |
| GENE | GRSF1 |
| DESCRIPTION | G-rich sequence factor-1 |
| NCBI ENTREZ ACCESS NO | 2926 |
| UNIPROT ACCESS NO | Q12849 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:66
| ACCESS NO | 101955 |
| GENE | GRINA |
| DESCRIPTION | Glutamate receptor ionotropic N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| NCBI ENTREZ ACCESS NO | 2907 |
| UNIPROT ACCESS NO | Q7Z429 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:67
| ACCESS NO | 101957 |
| GENE | GAS6 |
| DESCRIPTION | Growth arrest-specific 6 |
| NCBI ENTREZ ACCESS NO | 2621 |
| UNIPROT ACCESS NO | Q14393 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in asthma. Also significantly upregulated in the infected control group compared to non infected control. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GAS 6 for Mouse |
Record No:68
| ACCESS NO | 102003 |
| GENE | GPC6 |
| DESCRIPTION | Glypican 6 |
| NCBI ENTREZ ACCESS NO | 10082 |
| UNIPROT ACCESS NO | Q9Y625 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in lower airways in patients suffering from allergic rhinitis with or without asthma. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:69
| ACCESS NO | 102032 |
| GENE | GSN |
| DESCRIPTION | Gelsolin |
| NCBI ENTREZ ACCESS NO | 2934 |
| UNIPROT ACCESS NO | P06396 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma.(Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | BE0004161 |
| MONCLONAL ANTIBODY | Anti-Gelsolin for Human/Mouse |
Record No:70
| ACCESS NO | 102053 |
| GENE | GLIPR2 |
| DESCRIPTION | GLI pathogenesis-related 2 |
| NCBI ENTREZ ACCESS NO | 152007 |
| UNIPROT ACCESS NO | Q5VZR0 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Nasal epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | BE0003142 |
| MONCLONAL ANTIBODY | N/A |
Record No:71
| ACCESS NO | 102109 |
| GENE | GFI1 |
| DESCRIPTION | Growth factor independent 1 |
| NCBI ENTREZ ACCESS NO | 2672 |
| UNIPROT ACCESS NO | Q99684 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthma. Involved in IL2 driven Th2 expansion. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GFI1 for Human |
Record No:72
| ACCESS NO | 102133 |
| GENE | GNPDA1 |
| DESCRIPTION | Glucosamine-6-phosphate deaminase 1 |
| NCBI ENTREZ ACCESS NO | 10007 |
| UNIPROT ACCESS NO | P46926 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentialy expressed in asthma. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | BE0001567 |
| MONCLONAL ANTIBODY | N/A |