BROWSE RESULT OF H
| 69 Records |
| ACCESS NO | 100004 |
| GENE | HLA-DQB1 |
| DESCRIPTION | Major histocompatibility complex class II-DQ beta 1 |
| NCBI ENTREZ ACCESS NO | 3119 |
| UNIPROT ACCESS NO | P01920 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in antigen processing and presentation. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | BE0004466 |
| MONCLONAL ANTIBODY | Anti-HLA DQB1 for Human |
Record No:2
| ACCESS NO | 100006 |
| GENE | HBB |
| DESCRIPTION | Hemoglobin-beta |
| NCBI ENTREZ ACCESS NO | 3043 |
| UNIPROT ACCESS NO | P68871 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in low SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | BE0000629 |
| MONCLONAL ANTIBODY | N/A |
Record No:3
| ACCESS NO | 100010 |
| GENE | HBA2 |
| DESCRIPTION | Hemoglobin-alpha 2 |
| NCBI ENTREZ ACCESS NO | 3040 |
| UNIPROT ACCESS NO | P69905 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in low SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:4
| ACCESS NO | 100015 |
| GENE | HTATSF1 |
| DESCRIPTION | HIV-1 Tat specific factor 1 |
| NCBI ENTREZ ACCESS NO | 27336 |
| UNIPROT ACCESS NO | O43719 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in low SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HIV TAT specific factor 1 for Rat/Human |
Record No:5
| ACCESS NO | 100020 |
| GENE | HLA-DQA1 |
| DESCRIPTION | Major histocompatibility complex class II-DQ alpha 1 |
| NCBI ENTREZ ACCESS NO | 3117 |
| UNIPROT ACCESS NO | P01909 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in antigen processing and presentation. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | BE0002122 |
| MONCLONAL ANTIBODY | Anti-HLA-DQA1 antibody [EPR7300] for Mouse/Rat/Human |
Record No:6
| ACCESS NO | 100028 |
| GENE | HBA1 |
| DESCRIPTION | hemoglobin-alpha 1 |
| NCBI ENTREZ ACCESS NO | 3039 |
| UNIPROT ACCESS NO | P69905 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in low SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | BE0000130 |
| MONCLONAL ANTIBODY | N/A |
Record No:7
| ACCESS NO | 100032 |
| GENE | H2AFX |
| DESCRIPTION | H2A histone family member X |
| NCBI ENTREZ ACCESS NO | 3014 |
| UNIPROT ACCESS NO | P16104 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in high SEC group. It is a stress response protein. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | BE0002385 |
| MONCLONAL ANTIBODY | N/A |
Record No:8
| ACCESS NO | 100033 |
| GENE | HIST1H2AE |
| DESCRIPTION | Histone cluster 1- H2ae |
| NCBI ENTREZ ACCESS NO | 3012 |
| UNIPROT ACCESS NO | P04908 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in high SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Histone H2A (acetyl K5) [EP856Y] for Mouse/Rat/Human |
Record No:9
| ACCESS NO | 100040 |
| GENE | HSPA1A |
| DESCRIPTION | Heat shock 70kDa protein 1A |
| NCBI ENTREZ ACCESS NO | 3303 |
| UNIPROT ACCESS NO | P08107 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It protect cells from inflammatory molecules such as reactive oxygen species and are protective against pulmonary inflammations. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Hsp70 [5A5] for Mouse/Rat/Human |
Record No:10
| ACCESS NO | 100045 |
| GENE | HSPA6 |
| DESCRIPTION | Heat shock 70kDa protein 6 |
| NCBI ENTREZ ACCESS NO | 3310 |
| UNIPROT ACCESS NO | P17066 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It protect cells from inflammatory molecules such as reactive oxygen species and are protective against pulmonary inflammations. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HSPA6 for Mouse/Rat/Human |
Record No:11
| ACCESS NO | 100048 |
| GENE | HSPA1B |
| DESCRIPTION | Heat shock 70kDa protein 1B |
| NCBI ENTREZ ACCESS NO | 3304 |
| UNIPROT ACCESS NO | P08107 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It protect cells from inflammatory molecules such as reactive oxygen species and are protective against pulmonary inflammations. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HSPA1B for Human |
Record No:12
| ACCESS NO | 100050 |
| GENE | HLA-DRB4 |
| DESCRIPTION | Major histocompatibility complex class II - DR beta 4 |
| NCBI ENTREZ ACCESS NO | 3126 |
| UNIPROT ACCESS NO | P13760 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in high SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HLA-DRB4 for Human |
Record No:13
| ACCESS NO | 100081 |
| GENE | HBD |
| DESCRIPTION | Hemoglobin-delta |
| NCBI ENTREZ ACCESS NO | 3045 |
| UNIPROT ACCESS NO | P02042 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in innate immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:14
| ACCESS NO | 100133 |
| GENE | Hspa1a |
| DESCRIPTION | Heat shock protein 1A |
| NCBI ENTREZ ACCESS NO | 193740 |
| UNIPROT ACCESS NO | Q61696 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an IL-4 specific stress response gene induced in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Hsp70 [5A5] for Mouse/Rat/Human |
Record No:15
| ACCESS NO | 100134 |
| GENE | Hspa1b |
| DESCRIPTION | Heat shock protein 1B |
| NCBI ENTREZ ACCESS NO | 15511 |
| UNIPROT ACCESS NO | P17879 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an IL-4 specific stress response gene induced in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HSPA1B for Human |
Record No:16
| ACCESS NO | 100159 |
| GENE | HBEGF |
| DESCRIPTION | Heparin-binding EGF-like growth factor |
| NCBI ENTREZ ACCESS NO | 1839 |
| UNIPROT ACCESS NO | Q99075 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HB EGF for Human |
Record No:17
| ACCESS NO | 100209 |
| GENE | HPGD |
| DESCRIPTION | Hydroxyprostaglandin dehydrogenase 15-(NAD) |
| NCBI ENTREZ ACCESS NO | 3248 |
| UNIPROT ACCESS NO | P15428 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene codes for a metabolic enzyme significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | BE0000552 |
| MONCLONAL ANTIBODY | Anti-Prostaglandin dehydrogenase 1 for Human |
Record No:18
| ACCESS NO | 100319 |
| GENE | Hspa8 (LOC680121) |
| DESCRIPTION | Heat shock protein 8 (predicted) |
| NCBI ENTREZ ACCESS NO | 680121 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) and qRT- |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in antigen processing and presentation. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | BE0003775 |
| MONCLONAL ANTIBODY | N/A |
Record No:19
| ACCESS NO | 100332 |
| GENE | Hpx |
| DESCRIPTION | Hemopexin |
| NCBI ENTREZ ACCESS NO | 15458 |
| UNIPROT ACCESS NO | Q91X72 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced chemicals |
| SAMPLE | Serum and Broncho Alveolar Lavage (BAL) |
| TECHNIQUES | 2D DIGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | In this study hemopexin is upregulated in the serum and BAL fluid of asthmatic mice. It may lead to a stronger activation of CD4+ T cells. CD4+ T cells are a typical T cell subset related to asthma and increased in auricular lymph nodes of TDI-treated mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20860378 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Hemopexin for Human |
Record No:20
| ACCESS NO | 100338 |
| GENE | Hp |
| DESCRIPTION | Haptoglobin |
| NCBI ENTREZ ACCESS NO | 15439 |
| UNIPROT ACCESS NO | Q61646 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced chemicals |
| SAMPLE | Broncho Alveolar Lavage (BAL) |
| TECHNIQUES | 2D DIGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly up-regulated in BAL fluid of chemically induced asthmatic mice. It is involved in immune response modulation. It is synthesized during granulocyte differentiation and released after neutrophil activation to dampen potential damage to the surrounding tissue. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20860378 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:21
| ACCESS NO | 100339 |
| GENE | Hsp90b1 |
| DESCRIPTION | Tumor rejection antigen gp96 |
| NCBI ENTREZ ACCESS NO | 22027 |
| UNIPROT ACCESS NO | P08113 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced chemicals |
| SAMPLE | Auricular Lymph Nodes |
| TECHNIQUES | 2D DIGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in oxidative stress responses. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20860378 |
| DRUG TARGET | BE0001165 |
| MONCLONAL ANTIBODY | Anti-GRP94 [9G10] for Mouse/Rat/Human |
Record No:22
| ACCESS NO | 100375 |
| GENE | Hpx |
| DESCRIPTION | Hemopexin |
| NCBI ENTREZ ACCESS NO | 15458 |
| UNIPROT ACCESS NO | Q91X72 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Occupational asthma induced by chemicals |
| SAMPLE | Serum |
| TECHNIQUES | 2D DIGE and MALDI-TOF-MS and ELISA |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This a binding/transport protein. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23038679 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Hemopexin for Human |
Record No:23
| ACCESS NO | 100376 |
| GENE | Hp |
| DESCRIPTION | Haptoglobin |
| NCBI ENTREZ ACCESS NO | 15439 |
| UNIPROT ACCESS NO | Q61646 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | 2D PAGE andLC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Two isoforms of this proteins were upregulated and downregulated respectively after allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20029843 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:24
| ACCESS NO | 100393 |
| GENE | Hmox1 |
| DESCRIPTION | Heme oxygenase 1 |
| NCBI ENTREZ ACCESS NO | 15368 |
| UNIPROT ACCESS NO | P14901 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergen induced asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is down regulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15378764 |
| DRUG TARGET | BE0000735 |
| MONCLONAL ANTIBODY | Anti-Heme Oxygenase 1 for Mouse/Rat/Human |
Record No:25
| ACCESS NO | 100424 |
| GENE | HSPD1 |
| DESCRIPTION | Chaperonin 60 |
| NCBI ENTREZ ACCESS NO | 3329 |
| UNIPROT ACCESS NO | P10809 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | bronchial epithelial cells stimulated with TGF bet |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It plays cytoprotective roles in lung inflammation and injury by modulation of the balance between folding or aggregation and degradation of proteins. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20219718 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Hsp60 for Mouse/Rat/Human/Rabbit |
Record No:26
| ACCESS NO | 100425 |
| GENE | HSPA9 |
| DESCRIPTION | Heat shock 70 kDa protein 9B |
| NCBI ENTREZ ACCESS NO | 3313 |
| UNIPROT ACCESS NO | P38646 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | bronchial epithelial cells stimulated with TGF bet |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It plays cytoprotective roles in lung inflammation and injury by modulation of the balance between folding or aggregation and degradation of proteins. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20219718 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Grp75 [JG1] for Mouse/Rat/Human |
Record No:27
| ACCESS NO | 100427 |
| GENE | HNRNPH1 |
| DESCRIPTION | Heterogeneous nuclear ribonucleoprotein H1 |
| NCBI ENTREZ ACCESS NO | 3187 |
| UNIPROT ACCESS NO | P31943 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | bronchial epithelial cells stimulated with TGF bet |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in RNA processing. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20219718 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-hnRNP F+H for Mouse/Human |
Record No:28
| ACCESS NO | 100466 |
| GENE | HEYL |
| DESCRIPTION | Hes-related family bHLH transcription factor with YRPW motif-like |
| NCBI ENTREZ ACCESS NO | 26508 |
| UNIPROT ACCESS NO | Q9NQ87 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Airway smooth muscle cell (ASM) line |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is a transcription factor that is strongly induced upon dexamethasone teatment. However its induction strongly varies among different healthy anf fatal asthmatic airway smooth muscle cell lines. |
| GEO_PRIDE_ACCESS_NO | GSE3946 |
| REFERENCE | 21257922 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Axin 2 for Mouse/Rat/Human |
Record No:29
| ACCESS NO | 100498 |
| GENE | HIST1H2AH |
| DESCRIPTION | Histone cluster 1-H2ah |
| NCBI ENTREZ ACCESS NO | 85235 |
| UNIPROT ACCESS NO | Q96KK5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of glucocorticoid treatment |
| SAMPLE | Bronchial biopsy |
| TECHNIQUES | iTRAQ labelling followed by nano LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is downregulated in untreated asthma patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21939520 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:30
| ACCESS NO | 100510 |
| GENE | Hpgd |
| DESCRIPTION | Hydroxyprostaglandin dehydrogenase 15-(NAD) |
| NCBI ENTREZ ACCESS NO | 15446 |
| UNIPROT ACCESS NO | Q8VCC1 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung eosinophil |
| TECHNIQUES | Compugen mouse 22K oligonucleotide microarrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | the gene encoding 15 hydroxyprostaglandin dehydrogenase (PGDH) may contribute to resolution of asthma. PGDH is able to metabolize prostaglandin (PG)E2 to 15-keto-PGE2 and ablation of Hpgd in mice increases accumulation of PGE2 in the lung and as a consequence protects against bronchoconstriction. PGE2 may also limit pathology by inhibiting eosinophil accumulation in the lungs. |
| GEO_PRIDE_ACCESS_NO | GSE15345 |
| REFERENCE | 19395375 |
| DRUG TARGET | BE0000552 |
| MONCLONAL ANTIBODY | Anti-Prostaglandin dehydrogenase 1 for Human/Rabbit/Mouse |
Record No:31
| ACCESS NO | 100565 |
| GENE | HSPA4 |
| DESCRIPTION | HSP-70 |
| NCBI ENTREZ ACCESS NO | 3308 |
| UNIPROT ACCESS NO | P34932 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | CD3+T cell |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | A heat shock protein which protects the cells against reactive oxygen species and ill effects of numerous mediators. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17550934 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HSPA4 for Human/Mouse/Rat |
Record No:32
| ACCESS NO | 100616 |
| GENE | Hdac1 |
| DESCRIPTION | histone deacetylase 1 |
| NCBI ENTREZ ACCESS NO | 433759 |
| UNIPROT ACCESS NO | O09106 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Airway Inflammation |
| SAMPLE | CD4+ T cell |
| TECHNIQUES | Chip assay |
| OMICS | Epigenetics |
| STUDY | Low Throughput |
| COMMENTS | Loss of HDAC1 leads to increased allergic symptoms. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20702731 |
| DRUG TARGET | BE0002365 |
| MONCLONAL ANTIBODY | Anti HDAC1 antibody for human/mouse/ rat |
Record No:33
| ACCESS NO | 100637 |
| GENE | HPX |
| DESCRIPTION | Hemopexin |
| NCBI ENTREZ ACCESS NO | 3263 |
| UNIPROT ACCESS NO | P02790 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
| SAMPLE | Nasal fluid |
| TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Enriched in acute phase response pathway. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21887273 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Hemopexin for Human |
Record No:34
| ACCESS NO | 100638 |
| GENE | HRG |
| DESCRIPTION | Histidine-rich glycoprotein |
| NCBI ENTREZ ACCESS NO | 3273 |
| UNIPROT ACCESS NO | P04196 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
| SAMPLE | Nasal fluid |
| TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Decreased after glucocorticoid treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21887273 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HRG for Human |
Record No:35
| ACCESS NO | 100645 |
| GENE | HP |
| DESCRIPTION | Haptoglobin |
| NCBI ENTREZ ACCESS NO | 3240 |
| UNIPROT ACCESS NO | P00738 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma proteins |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Expressed by eosinophils.Involved in tissue remodelling and fibrosis. Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21471098 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Haptoglobin for Mouse/Rat/Human |
Record No:36
| ACCESS NO | 100646 |
| GENE | HPX |
| DESCRIPTION | Hemopexin |
| NCBI ENTREZ ACCESS NO | 3263 |
| UNIPROT ACCESS NO | P02790 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma proteins |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Acute phase protein which is synthesized by the liver and have important antiinflammatory properties through inhibition of oxidative stress. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21471098 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Hemopexin for Human |
Record No:37
| ACCESS NO | 100653 |
| GENE | HRG |
| DESCRIPTION | Histidine-rich glycoprotein |
| NCBI ENTREZ ACCESS NO | 3273 |
| UNIPROT ACCESS NO | P04196 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma proteins |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in coagulation cascade. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21471098 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HRG for Human |
Record No:38
| ACCESS NO | 100666 |
| GENE | Hnrnpa3 |
| DESCRIPTION | Heterogeneous nuclear ribonucleoprotein A3 |
| NCBI ENTREZ ACCESS NO | 229279 |
| UNIPROT ACCESS NO | Q8BG05 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof and Western Blotting |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Responsible for RNA trafficking from nucleus to cytoplasm. Overexpressed in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:39
| ACCESS NO | 100688 |
| GENE | Hba-a1 |
| DESCRIPTION | Alpha globin |
| NCBI ENTREZ ACCESS NO | 15122 |
| UNIPROT ACCESS NO | Q91VB8 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergen induced asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | BE0000130 |
| MONCLONAL ANTIBODY | Anti-Hemoglobin subunit alpha for Mouse/Rat/Human |
Record No:40
| ACCESS NO | 100710 |
| GENE | HPX |
| DESCRIPTION | Hemopexin |
| NCBI ENTREZ ACCESS NO | 3263 |
| UNIPROT ACCESS NO | P02790 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Sputum |
| TECHNIQUES | LC-MS/MS and western blot |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | an acute-phase heme-binding protein was found to be upregulated in exercise induced sputum of asthmatic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21906793 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Hemopexin for Mouse/Rat/Human |
Record No:41
| ACCESS NO | 100727 |
| GENE | HPX |
| DESCRIPTION | Hemopexin precursor |
| NCBI ENTREZ ACCESS NO | 3263 |
| UNIPROT ACCESS NO | P02790 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Blood plasma |
| TECHNIQUES | MALDI TOF MS and LC-MS/MS and Western Blot |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in atopic dermatitis patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19116453 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Hemopexin for Human |
Record No:42
| ACCESS NO | 100728 |
| GENE | HP |
| DESCRIPTION | HP protein |
| NCBI ENTREZ ACCESS NO | 3240 |
| UNIPROT ACCESS NO | P00738 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Blood plasma |
| TECHNIQUES | MALDI TOF MS and LC-MS/MS and Western Blot |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in atopic dermatitis patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19116453 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Haptoglobin for Human/Mouse/Rat |
Record No:43
| ACCESS NO | 100806 |
| GENE | Hist1h2ad |
| DESCRIPTION | Histone H2A type 1 |
| NCBI ENTREZ ACCESS NO | 319165 |
| UNIPROT ACCESS NO | P22752 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in short time allergen exposure and downregulated in long exposure |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:44
| ACCESS NO | 100934 |
| GENE | Hba-a1 |
| DESCRIPTION | Hemoglobin alpha adult chain 1 |
| NCBI ENTREZ ACCESS NO | 15122 |
| UNIPROT ACCESS NO | Q91VB8 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after induction with food allergens. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:45
| ACCESS NO | 101009 |
| GENE | HDC |
| DESCRIPTION | Histidine decarboxylase |
| NCBI ENTREZ ACCESS NO | 3067 |
| UNIPROT ACCESS NO | P19113 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows highest expression in patients with eosinophilic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | BE0000002 |
| MONCLONAL ANTIBODY | N/A |
Record No:46
| ACCESS NO | 101035 |
| GENE | HAL |
| DESCRIPTION | Histidine ammonia-lyase |
| NCBI ENTREZ ACCESS NO | 3034 |
| UNIPROT ACCESS NO | P42357 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly upregulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | BE0000086 |
| MONCLONAL ANTIBODY | N/A |
Record No:47
| ACCESS NO | 101207 |
| GENE | HS3ST6 |
| DESCRIPTION | Heparan sulfate glucosamine 3-O-sulfotransferase 6 |
| NCBI ENTREZ ACCESS NO | 64711 |
| UNIPROT ACCESS NO | Q96QI5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:48
| ACCESS NO | 101218 |
| GENE | HARS2 |
| DESCRIPTION | Probable histidyl-tRNA synthetase mitochondrial |
| NCBI ENTREZ ACCESS NO | 23438 |
| UNIPROT ACCESS NO | P49590 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HARS2 for Human |
Record No:49
| ACCESS NO | 101230 |
| GENE | HSPA6 |
| DESCRIPTION | heat shock 70kDa protein 6 |
| NCBI ENTREZ ACCESS NO | 3310 |
| UNIPROT ACCESS NO | P17066 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Skin allergy induced by formaldehyde |
| SAMPLE | THP-1 cell line |
| TECHNIQUES | qPCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This inflammatory marker is upregulated upon bronopol challenge in a time depenent manner. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22034943 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HSPA6 for Mouse/Rat/Human |
Record No:50
| ACCESS NO | 101232 |
| GENE | HMOX1 |
| DESCRIPTION | Heme oxygenase (decycling) 1 |
| NCBI ENTREZ ACCESS NO | 3162 |
| UNIPROT ACCESS NO | P09601 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Skin allergy induced by formaldehyde |
| SAMPLE | THP-1 cell line |
| TECHNIQUES | qPCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This inflammatory marker is upregulated upon bronopol challenge in a time depenent manner. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22034943 |
| DRUG TARGET | BE0000735 |
| MONCLONAL ANTIBODY | Anti-Heme Oxygenase 1 for Mouse/Human/Rat |
Record No:51
| ACCESS NO | 101272 |
| GENE | HMGB1 |
| DESCRIPTION | High mobility group box 1 |
| NCBI ENTREZ ACCESS NO | 3146 |
| UNIPROT ACCESS NO | P09429 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | A neutrophilic chemoattractant and expressed significantly higher in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21041074 |
| DRUG TARGET | BE0003428 |
| MONCLONAL ANTIBODY | Anti-HMGB1 for Rat/Mouse/Human |
Record No:52
| ACCESS NO | 101392 |
| GENE | Hpx |
| DESCRIPTION | Hemopexin |
| NCBI ENTREZ ACCESS NO | 15458 |
| UNIPROT ACCESS NO | Q91X72 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Elevated in chronically inflammed lungs. Controls Chloride channel activity for mucus production. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Hemopexin for Human |
Record No:53
| ACCESS NO | 101461 |
| GENE | Hcls1 |
| DESCRIPTION | Hematopoietic cell specific Lyn substrate 1 |
| NCBI ENTREZ ACCESS NO | 15163 |
| UNIPROT ACCESS NO | P49710 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HCLS1 for Human |
Record No:54
| ACCESS NO | 101590 |
| GENE | Hspa5 |
| DESCRIPTION | Heat shock protein 5 |
| NCBI ENTREZ ACCESS NO | 14828 |
| UNIPROT ACCESS NO | P20029 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | A heat shock protein present in the endoplasmic reticulum. Expressed after IL13induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | BE0001098 |
| MONCLONAL ANTIBODY | Anti-GRP78 for Mouse/Rat/Human |
Record No:55
| ACCESS NO | 101619 |
| GENE | Hpgd |
| DESCRIPTION | Hydroxyprostaglandin dehydrogenase 15 |
| NCBI ENTREZ ACCESS NO | 15446 |
| UNIPROT ACCESS NO | Q8VCC1 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in metabolism and expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | BE0000552 |
| MONCLONAL ANTIBODY | N/A |
Record No:56
| ACCESS NO | 101629 |
| GENE | Hp |
| DESCRIPTION | Haptoglobin |
| NCBI ENTREZ ACCESS NO | 15439 |
| UNIPROT ACCESS NO | Q61646 |
| ORGANISM | Female Balb/c Mice |
| DISEASE PHENOTYPE | Food allergy caused by Ovomucoid |
| SAMPLE | Plasma |
| TECHNIQUES | MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in Ovomucoid sensitized mouse. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17897766 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Haptoglobin for Mouse/Rat/Human |
Record No:57
| ACCESS NO | 101632 |
| GENE | Hba |
| DESCRIPTION | Hemoglobin alpha |
| NCBI ENTREZ ACCESS NO | 15121 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Female Balb/c Mice |
| DISEASE PHENOTYPE | Food allergy caused by Ovomucoid |
| SAMPLE | Plasma |
| TECHNIQUES | MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed in Ovomucoid sensitized mouse. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17897766 |
| DRUG TARGET | BE0000130 |
| MONCLONAL ANTIBODY | Anti-Hemoglobin subunit alpha for Human |
Record No:58
| ACCESS NO | 101794 |
| GENE | HRG |
| DESCRIPTION | Histidine-rich glycoprotein |
| NCBI ENTREZ ACCESS NO | 3273 |
| UNIPROT ACCESS NO | HRG |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This serum protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HRG [MM0331-6Z48] for Human |
Record No:59
| ACCESS NO | 101815 |
| GENE | HMGB1 |
| DESCRIPTION | HMG-1 |
| NCBI ENTREZ ACCESS NO | 3146 |
| UNIPROT ACCESS NO | P09429 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0003428 |
| MONCLONAL ANTIBODY | N/A |
Record No:60
| ACCESS NO | 101818 |
| GENE | HSPE1 |
| DESCRIPTION | Chaperonin 10-related protein |
| NCBI ENTREZ ACCESS NO | 3336 |
| UNIPROT ACCESS NO | P61604 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:61
| ACCESS NO | 101824 |
| GENE | HNRNPC |
| DESCRIPTION | HNRPC protein |
| NCBI ENTREZ ACCESS NO | 3183 |
| UNIPROT ACCESS NO | P07910 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:62
| ACCESS NO | 101845 |
| GENE | HP |
| DESCRIPTION | Haptoglobin |
| NCBI ENTREZ ACCESS NO | 3240 |
| UNIPROT ACCESS NO | P00738 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucus |
| TECHNIQUES | LC-MS/MS and western blot |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It showed 0.7 fold expression change in rhinitis patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24290289 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:63
| ACCESS NO | 101866 |
| GENE | HPX |
| DESCRIPTION | Hemopexin precursor |
| NCBI ENTREZ ACCESS NO | 3263 |
| UNIPROT ACCESS NO | P02790 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Plasma |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is down regulated in atopic dermatitis patient. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19116453 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Hemopexin for Human |
Record No:64
| ACCESS NO | 101868 |
| GENE | HP |
| DESCRIPTION | Haptoglobin |
| NCBI ENTREZ ACCESS NO | 3240 |
| UNIPROT ACCESS NO | P00738 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Plasma |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in atopic dermatitis patient. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19116453 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:65
| ACCESS NO | 101930 |
| GENE | HNRNPR |
| DESCRIPTION | Heterogeneous nuclear ribonucleoprotein R |
| NCBI ENTREZ ACCESS NO | 10236 |
| UNIPROT ACCESS NO | O43390 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:66
| ACCESS NO | 102033 |
| GENE | HOXA1 |
| DESCRIPTION | Homeobox A1 |
| NCBI ENTREZ ACCESS NO | 3198 |
| UNIPROT ACCESS NO | P49639 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma.(Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:67
| ACCESS NO | 102054 |
| GENE | HR |
| DESCRIPTION | Hairless homolog |
| NCBI ENTREZ ACCESS NO | 55806 |
| UNIPROT ACCESS NO | O43593 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Nasal epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:68
| ACCESS NO | 102080 |
| GENE | HPGD |
| DESCRIPTION | Hydroxyprostaglandin dehydrogenase |
| NCBI ENTREZ ACCESS NO | 3248 |
| UNIPROT ACCESS NO | P15428 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in leukotriene and prostaglandin signalling. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | BE0000552 |
| MONCLONAL ANTIBODY | Anti-Prostaglandin dehydrogenase 1 for Human |
Record No:69
| ACCESS NO | 102117 |
| GENE | HIPK2 |
| DESCRIPTION | Homeodomain-interacting protein kinase 2 |
| NCBI ENTREZ ACCESS NO | 28996 |
| UNIPROT ACCESS NO | Q9H2X6 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in atopic asthma. Involved in Treg expression and function. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HIPK2 for Mouse/Human |