BROWSE RESULT OF I

259 Records

 

Record No:1


ACCESS NO100034
GENEINPP4B
DESCRIPTIONInositol polyphosphate-4-phosphatase type II
NCBI ENTREZ ACCESS NO8821
UNIPROT ACCESS NOO15327
ORGANISMHuman
DISEASE PHENOTYPEAsthma ( comparison between high and low socio-economic conditions [SEC])
SAMPLECD2+ cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene is upregulated more in high SEC group.
GEO_PRIDE_ACCESS_NOGSE7894
REFERENCE19001005
DRUG TARGET
MONCLONAL ANTIBODYAnti-INPP4B for Mouse/Rat/Human


Record No:2


ACCESS NO100073
GENEIL1RAP
DESCRIPTIONInterleukin 1 receptor accessory protein
NCBI ENTREZ ACCESS NO3556
UNIPROT ACCESS NOQ9NPH3
ORGANISMHuman
DISEASE PHENOTYPEAcute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESMicroarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is involved in innate immunity.
GEO_PRIDE_ACCESS_NOGSE16032
REFERENCE19620293
DRUG TARGETBE0000565
MONCLONAL ANTIBODYAnti-IL1RAPL1 for Mouse/Human


Record No:3


ACCESS NO100086
GENEIL13RA1
DESCRIPTIONInterleukin 13 receptor alpha 1
NCBI ENTREZ ACCESS NO3597
UNIPROT ACCESS NOP78552
ORGANISMHuman
DISEASE PHENOTYPEAcute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESMicroarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is involved in adaptive immunity.
GEO_PRIDE_ACCESS_NOGSE16032
REFERENCE19620293
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL13 receptor alpha 1 for Human


Record No:4


ACCESS NO100087
GENEIL10 (IL-10)
DESCRIPTIONInterleukin 10
NCBI ENTREZ ACCESS NO3586
UNIPROT ACCESS NOP22301
ORGANISMHuman
DISEASE PHENOTYPEAcute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESMicroarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is involved in adaptive immunity.
GEO_PRIDE_ACCESS_NOGSE16032
REFERENCE19620293
DRUG TARGETBE0002484
MONCLONAL ANTIBODYAnti-IL10 for Mouse


Record No:5


ACCESS NO100088
GENEIL18
DESCRIPTIONInterleukin 18
NCBI ENTREZ ACCESS NO3606
UNIPROT ACCESS NOQ14116
ORGANISMHuman
DISEASE PHENOTYPEAcute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESMicroarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is involved in adaptive immunity.
GEO_PRIDE_ACCESS_NOGSE16032
REFERENCE19620293
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL18 for Pig


Record No:6


ACCESS NO100090
GENEIDO1 (INDO)
DESCRIPTIONIndoleamine dioxygenase 1
NCBI ENTREZ ACCESS NO3620
UNIPROT ACCESS NOP14902
ORGANISMHuman
DISEASE PHENOTYPEAcute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESMicroarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is involved in adaptive immunity.
GEO_PRIDE_ACCESS_NOGSE16032
REFERENCE19620293
DRUG TARGETBE0000693
MONCLONAL ANTIBODYAnti-Indoleamine 2-3-dioxygenase for Human


Record No:7


ACCESS NO100097
GENEItlnb
DESCRIPTIONIntelectin b
NCBI ENTREZ ACCESS NO493583
UNIPROT ACCESS NOO88310
ORGANISMMouse
DISEASE PHENOTYPEAllergic asthma and the role of IL-4 and IL-13
SAMPLELung tissue
TECHNIQUESDNA Affymetrix microarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSThis gene is an epithelial product and significantly upregulated in allergic asthma. It is induced upon allergen challenge and as well as combinatorial effect of IL-4 plus IL-13.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19249085
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:8


ACCESS NO100109
GENEItgax
DESCRIPTIONIntegrin a X
NCBI ENTREZ ACCESS NO16411
UNIPROT ACCESS NOQ9QXH4
ORGANISMMouse
DISEASE PHENOTYPEAllergic asthma and the role of IL-4 and IL-13
SAMPLELung tissue
TECHNIQUESDNA Affymetrix microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is an IL-4 specific immunomodulatory gene in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19249085
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:9


ACCESS NO100119
GENEIfi204 (Ifi16)
DESCRIPTIONIFN-gamma–inducible protein 16
NCBI ENTREZ ACCESS NO15951
UNIPROT ACCESS NOP15092
ORGANISMMouse
DISEASE PHENOTYPEAllergic asthma and the role of IL-4 and IL-13
SAMPLELung tissue
TECHNIQUESDNA Affymetrix microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis host immune response gene is specifically induced by Th2 cytokines such as IL-4 and IL-13.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19249085
DRUG TARGET
MONCLONAL ANTIBODYAnti-IFI16 for Human


Record No:10


ACCESS NO100120
GENEIfi47
DESCRIPTIONIFN-gamma–inducible protein 47
NCBI ENTREZ ACCESS NO15953
UNIPROT ACCESS NOQ61635
ORGANISMMouse
DISEASE PHENOTYPEAllergic asthma and the role of IL-4 and IL-13
SAMPLELung tissue
TECHNIQUESDNA Affymetrix microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis host immune response gene is specifically induced by Th2 cytokines such as IL-4 and IL-13.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19249085
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:11


ACCESS NO100129
GENEIgtp
DESCRIPTIONInterferon gamma induced GTPase
NCBI ENTREZ ACCESS NO16145
UNIPROT ACCESS NOQ9DCE9
ORGANISMMouse
DISEASE PHENOTYPEAllergic asthma and the role of IL-4 and IL-13
SAMPLELung tissue
TECHNIQUESDNA Affymetrix microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is an IL-4 specific host immune responsive gene induced in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19249085
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:12


ACCESS NO100130
GENEIigp1
DESCRIPTIONInterferon-inducible GTPase 1
NCBI ENTREZ ACCESS NO60440
UNIPROT ACCESS NOQ9QZ85
ORGANISMMouse
DISEASE PHENOTYPEAllergic asthma and the role of IL-4 and IL-13
SAMPLELung tissue
TECHNIQUESDNA Affymetrix microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is an IL-4 specific host immune responsive gene induced in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19249085
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:13


ACCESS NO100144
GENEIL1A
DESCRIPTIONInterleukin - 1
NCBI ENTREZ ACCESS NO3552
UNIPROT ACCESS NOP01583
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is a cell communication protein significantly upregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL1 alpha for Human


Record No:14


ACCESS NO100148
GENEIL6
DESCRIPTIONInterleukin 6
NCBI ENTREZ ACCESS NO3569
UNIPROT ACCESS NOP05231
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSThis is a cell communication protein significantly upregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGETBE0000918
MONCLONAL ANTIBODYAnti-IL6 for Rat/Human


Record No:15


ACCESS NO100150
GENEIL11
DESCRIPTIONInterleukin 11
NCBI ENTREZ ACCESS NO3589
UNIPROT ACCESS NOP20809
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSThis is a cell communication protein significantly upregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGETBE0000416
MONCLONAL ANTIBODYN/A


Record No:16


ACCESS NO100156
GENEIL1RL1
DESCRIPTIONInterleukin 1 receptor-like 1
NCBI ENTREZ ACCESS NO9173
UNIPROT ACCESS NOQ01638
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is a cell communication protein significantly upregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:17


ACCESS NO100163
GENEIRAK2
DESCRIPTIONInterleukin-1 receptor-associated kinase 2
NCBI ENTREZ ACCESS NO3656
UNIPROT ACCESS NOO43187
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSThis is a cell communication protein significantly upregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGETBE0000565
MONCLONAL ANTIBODYAnti-IRAK2 for Mouse/Rat/Human


Record No:18


ACCESS NO100169
GENEITGB8
DESCRIPTIONIntegrin beta 8
NCBI ENTREZ ACCESS NO3696
UNIPROT ACCESS NOP26012
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is a cell communication protein significantly upregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYAnti-Integrin beta 8 for Human


Record No:19


ACCESS NO100171
GENEIL1B
DESCRIPTIONInterleukin 1 beta
NCBI ENTREZ ACCESS NO3553
UNIPROT ACCESS NOP01584
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is a cell communication protein significantly upregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGETBE0001051
MONCLONAL ANTIBODYAnti-IL1B for Human


Record No:20


ACCESS NO100186
GENEIL13RA2
DESCRIPTIONInterleukin 13 receptor alpha 2
NCBI ENTREZ ACCESS NO3598
UNIPROT ACCESS NOQ14627
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSThis is a receptor protein significantly up regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGETBE0002421
MONCLONAL ANTIBODYAnti-IL13 receptor alpha 2 for Human


Record No:21


ACCESS NO100226
GENEIER3
DESCRIPTIONImmediate early response 3
NCBI ENTREZ ACCESS NO8870
UNIPROT ACCESS NOP46695
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene is significantly up regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:22


ACCESS NO100230
GENEIGFL1
DESCRIPTIONInsulin growth factor-like family member 1
NCBI ENTREZ ACCESS NO374918
UNIPROT ACCESS NOQ6UW32
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene is significantly up regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:23


ACCESS NO100245
GENEIL8
DESCRIPTIONInterleukin 8
NCBI ENTREZ ACCESS NO3576
UNIPROT ACCESS NOP10145
ORGANISMHuman
DISEASE PHENOTYPEAsthma exacerbation after rhinovirus infection
SAMPLEPrimary bronchial epithelial cells
TECHNIQUESAffymetrix GeneChip Microarray and qRT-PCR followe
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is one of the major chemokine mediators of the inflammatory response.
GEO_PRIDE_ACCESS_NOGSE13396
REFERENCE19710636
DRUG TARGETBE0000961
MONCLONAL ANTIBODYAnti-IL8 for Human


Record No:24


ACCESS NO100247
GENEIL1R2
DESCRIPTIONInterleukin 1 receptor type II
NCBI ENTREZ ACCESS NO7850
UNIPROT ACCESS NOP27930
ORGANISMHuman
DISEASE PHENOTYPEAsthma exacerbation after rhinovirus infection
SAMPLEPrimary bronchial epithelial cells
TECHNIQUESAffymetrix GeneChip Microarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt acts as a decoy receptor that inhibits the activity of interleukin ligands.
GEO_PRIDE_ACCESS_NOGSE13396
REFERENCE19710636
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL1 Receptor II for Human


Record No:25


ACCESS NO100253
GENEIL13RA2
DESCRIPTIONInterleukin 13 receptor-alpha 2
NCBI ENTREZ ACCESS NO3598
UNIPROT ACCESS NOQ14627
ORGANISMHuman
DISEASE PHENOTYPEAsthma exacerbation after rhinovirus infection
SAMPLEPrimary bronchial epithelial cells
TECHNIQUESAffymetrix GeneChip Microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis cytokine receptor is upregulated in rhinovirus induced allergic asthma.
GEO_PRIDE_ACCESS_NOGSE13396
REFERENCE19710636
DRUG TARGETBE0002421
MONCLONAL ANTIBODYAnti-IL13 receptor alpha 2 for Human


Record No:26


ACCESS NO100257
GENEIL6
DESCRIPTIONInterleukin 6
NCBI ENTREZ ACCESS NO3569
UNIPROT ACCESS NOP05231
ORGANISMHuman
DISEASE PHENOTYPEAsthma exacerbation after rhinovirus infection
SAMPLEPrimary bronchial epithelial cells
TECHNIQUESAffymetrix GeneChip Microarray and qRT-PCR followe
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSThis cytokine gene is more upregulated after rhinovirus infection as compared to normal asthma.
GEO_PRIDE_ACCESS_NOGSE13396
REFERENCE19710636
DRUG TARGETBE0000918
MONCLONAL ANTIBODYAnti-IL6 for Rat/Human


Record No:27


ACCESS NO100261
GENEIVNS1ABP
DESCRIPTIONInfluenza virus NS1A binding protein
NCBI ENTREZ ACCESS NO10625
UNIPROT ACCESS NOQ9Y6Y0
ORGANISMHuman
DISEASE PHENOTYPEAsthma exacerbation after rhinovirus infection
SAMPLEPrimary bronchial epithelial cells
TECHNIQUESAffymetrix GeneChip Microarray
OMICSGenomics
STUDY High Throughput
COMMENTSIt is a rhinoviral infection responsive protein down regulated in asthma.
GEO_PRIDE_ACCESS_NOGSE13396
REFERENCE19710636
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:28


ACCESS NO100269
GENEIFI44
DESCRIPTIONInterferon-induced protein 44
NCBI ENTREZ ACCESS NO10561
UNIPROT ACCESS NOQ8TCB0
ORGANISMHuman
DISEASE PHENOTYPEAsthma exacerbation after rhinovirus infection
SAMPLEPrimary bronchial epithelial cells
TECHNIQUESAffymetrix GeneChip Microarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is a virus responsive protein and also participates in cell-cycle arrest.
GEO_PRIDE_ACCESS_NOGSE13396
REFERENCE19710636
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:29


ACCESS NO100270
GENEIL1B
DESCRIPTIONInterleukin 1 beta
NCBI ENTREZ ACCESS NO3553
UNIPROT ACCESS NOP01584
ORGANISMHuman
DISEASE PHENOTYPEAsthma exacerbation after rhinovirus infection
SAMPLEPrimary bronchial epithelial cells
TECHNIQUESAffymetrix GeneChip Microarray and qRT-PCR followe
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSThis is a proinflammatory cytokine found in the cell culture supernatent after rhinovirus infection.
GEO_PRIDE_ACCESS_NOGSE13396
REFERENCE19710636
DRUG TARGETBE0001051
MONCLONAL ANTIBODYAnti-IL1B for Human


Record No:30


ACCESS NO100272
GENEINHBA
DESCRIPTIONInhibin-beta A
NCBI ENTREZ ACCESS NO3624
UNIPROT ACCESS NOP08476
ORGANISMHuman
DISEASE PHENOTYPEAsthma exacerbation after rhinovirus infection
SAMPLEPrimary bronchial epithelial cells
TECHNIQUESAffymetrix GeneChip Microarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt shows upregulation in uninfected asthma group. It is involved in airway repair and remodelling.
GEO_PRIDE_ACCESS_NOGSE13396
REFERENCE19710636
DRUG TARGET
MONCLONAL ANTIBODYAnti-Inhibin beta A for Mouse/Rat/Human


Record No:31


ACCESS NO100284
GENEIGF2BP2
DESCRIPTIONInsulin-like growth factor 2 mRNA binding protein 2
NCBI ENTREZ ACCESS NO10644
UNIPROT ACCESS NOQ9Y6M1
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESIllumina Human Ref8 BeadChip arrays
OMICSGenomics
STUDY High Throughput
COMMENTSIt is upregulated in asthma exacerbation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19187333
DRUG TARGET
MONCLONAL ANTIBODYAnti-IGF2BP2 for Mouse/Rat/Human


Record No:32


ACCESS NO100286
GENEIcam1
DESCRIPTIONIntercellular adhesion molecule 1
NCBI ENTREZ ACCESS NO15894
UNIPROT ACCESS NOP13597
ORGANISMMouse
DISEASE PHENOTYPEAsthma induced by Aspergillus fumigatus allergens
SAMPLEPeripheral blood monocytes
TECHNIQUESDNA Microarray
OMICSGenomics
STUDY High Throughput
COMMENTSResults of this study showed a decrease level in its transcription. This may be due to the fact that the monocytes do not encounter the particulate fungal conidia until reaching the lung.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20840155
DRUG TARGETBE0001085
MONCLONAL ANTIBODYN/A


Record No:33


ACCESS NO100288
GENEItgb4
DESCRIPTIONintegrin beta-4
NCBI ENTREZ ACCESS NO192897
UNIPROT ACCESS NOA2A863
ORGANISMMouse
DISEASE PHENOTYPEAsthma induced by Aspergillus fumigatus allergens
SAMPLEPeripheral blood monocytes
TECHNIQUESDNA Microarray
OMICSGenomics
STUDY High Throughput
COMMENTSIt is involved in the movement of immune cells required for cell mediated immune response.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20840155
DRUG TARGETBE0003298
MONCLONAL ANTIBODYAnti-Integrin beta 4 [M126] for Mouse/Rat/Human


Record No:34


ACCESS NO100301
GENEIl18bp
DESCRIPTIONInterleukin-18 binding protein
NCBI ENTREZ ACCESS NO16068
UNIPROT ACCESS NOQ9Z0M9
ORGANISMMouse
DISEASE PHENOTYPEAsthma induced by Aspergillus fumigatus allergens
SAMPLEPeripheral blood monocytes
TECHNIQUESDNA Microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis protein is involved in Cytokine signaling. It has been observed to be down regulated in the present study.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20840155
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL18 binding protein for Rat/Human


Record No:35


ACCESS NO100305
GENEIl1rapl2
DESCRIPTIONInterleukin-1 receptor accessory protein-like 2
NCBI ENTREZ ACCESS NO60367
UNIPROT ACCESS NOQ9ERS6
ORGANISMMouse
DISEASE PHENOTYPEAsthma induced by Aspergillus fumigatus allergens
SAMPLEPeripheral blood monocytes
TECHNIQUESDNA Microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is a cytokine receptor. It has been observed to be up regulated in the present study.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20840155
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL1RAPL2 for Human


Record No:36


ACCESS NO100369
GENEInmt
DESCRIPTIONThioether S-methyltransferase
NCBI ENTREZ ACCESS NO21743
UNIPROT ACCESS NOP40936
ORGANISMMouse
DISEASE PHENOTYPEAllergen induced asthma and Dexamethasone treatment
SAMPLEBroncho Alveolar Lavage (BAL)
TECHNIQUES2D PAGE and MALDI-TOF-MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis gene contributes to Selenium metabolism.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15378748
DRUG TARGET
MONCLONAL ANTIBODYAnti-Inmt for Human/Rat?mouse


Record No:37


ACCESS NO100404
GENEICAM1
DESCRIPTIONIntercellular adhesion molecule 1 (ICAM-1)
NCBI ENTREZ ACCESS NO102138837
UNIPROT ACCESS NON/A
ORGANISMMonkey
DISEASE PHENOTYPEAllergic asthma
SAMPLELung tissue
TECHNIQUESDNA microarrays and Quantitative RT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is involved in tissue remodeling. It is not or minimally regulated by IL4.
GEO_PRIDE_ACCESS_NON/A
REFERENCE12049661
DRUG TARGETBE0001085
MONCLONAL ANTIBODYAnti-ICAM1 for Rat/Human


Record No:38


ACCESS NO100513
GENEInmt
DESCRIPTIONIndolethylamine N-methyltransferase
NCBI ENTREZ ACCESS NO21743
UNIPROT ACCESS NOP40936
ORGANISMMouse
DISEASE PHENOTYPEAllergic asthma
SAMPLELung eosinophil
TECHNIQUESCompugen mouse 22K oligonucleotide microarrays
OMICSGenomics
STUDY High Throughput
COMMENTSDownregulated in asthma susceptible strains.
GEO_PRIDE_ACCESS_NOGSE15345
REFERENCE19395375
DRUG TARGET
MONCLONAL ANTIBODYAnti-INMT for Human/Rabbit/Mouse


Record No:39


ACCESS NO100517
GENEIl10
DESCRIPTIONInterleukin 10
NCBI ENTREZ ACCESS NO16153
UNIPROT ACCESS NOP18893
ORGANISMMouse
DISEASE PHENOTYPEAsthma and role of Galectin-4
SAMPLELung tissue
TECHNIQUESMicroarray-affymetrix + Real time RT PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is an intermediary cytokine involved in SOCS3 expression.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21547260
DRUG TARGETBE0002484
MONCLONAL ANTIBODYAnti-IL10 for Human/Rat/Mouse


Record No:40


ACCESS NO100519
GENEINHA
DESCRIPTIONinhibin alpha
NCBI ENTREZ ACCESS NO3623
UNIPROT ACCESS NOP05111
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLECD4+ T cell
TECHNIQUESRT PCR and microarray-affymetrix
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSUpregulated in CD4+ T cells.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18269679
DRUG TARGETBE0000332
MONCLONAL ANTIBODYAnti-Inhibin alpha for Human/Rat/Mouse


Record No:41


ACCESS NO100520
GENEINHBA
DESCRIPTIONActivin A
NCBI ENTREZ ACCESS NO3624
UNIPROT ACCESS NOP08476
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLECD4+ T cell
TECHNIQUESRT PCR and microarray-affymetrix
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSUpregulated in CD4+ T cells. Currently it has been identified as Th2 cytokine.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18269679
DRUG TARGET
MONCLONAL ANTIBODYAnti-inhibin beta A for Human/Rat/Mouse


Record No:42


ACCESS NO100521
GENEIL9
DESCRIPTIONInterleukin 9
NCBI ENTREZ ACCESS NO3578
UNIPROT ACCESS NOP15248
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLECD4+ T cell
TECHNIQUESRT PCR and microarray-affymetrix
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSTH2 cell-derived cytokine involved in the development of the asthmatic phenotype.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18269679
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL9 for Human


Record No:43


ACCESS NO100522
GENEIL13
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO3596
UNIPROT ACCESS NOP35225
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLECD4+ T cell
TECHNIQUESRT PCR and microarray-affymetrix
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSTH2 cell-derived cytokine involved in the development of the asthmatic phenotype.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18269679
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:44


ACCESS NO100523
GENEIL10
DESCRIPTIONInterleukin 10
NCBI ENTREZ ACCESS NO3586
UNIPROT ACCESS NOP22301
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLECD4+ T cell
TECHNIQUESRT PCR and microarray-affymetrix
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSOverexpressed in atopic individuals.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18269679
DRUG TARGETBE0002484
MONCLONAL ANTIBODYAnti-IL10 for Human/Rat/Mouse


Record No:45


ACCESS NO100532
GENEIghg1(IgH-4)
DESCRIPTIONImmunoglobulin heavy constant gamma 1
NCBI ENTREZ ACCESS NO16017
UNIPROT ACCESS NOP01868
ORGANISMMouse
DISEASE PHENOTYPEAcute and chronic asthma
SAMPLETissue from left lung
TECHNIQUESAffymetrix gene chip cDNA microarray
OMICSGenomics
STUDY High Throughput
COMMENTSAsthma biomarker.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18087161
DRUG TARGETBE0002815
MONCLONAL ANTIBODYAnti-Human IgG [EPR4421] for human


Record No:46


ACCESS NO100549
GENEIl2rb
DESCRIPTIONInterleukin 2 receptor-beta
NCBI ENTREZ ACCESS NO16185
UNIPROT ACCESS NOP16297
ORGANISMMouse
DISEASE PHENOTYPEAsthma
SAMPLETissue from bronchial biopsy
TECHNIQUESMicroarray-Affymetrix HG-U95Av2 GeneChips
OMICSGenomics
STUDY High Throughput
COMMENTSIt is an immune signalling molecule. (data collected from supplementary table).
GEO_PRIDE_ACCESS_NOGSE15823
REFERENCE15038835
DRUG TARGETBE0000651
MONCLONAL ANTIBODYAnti-IL2 receptor beta (Allophycocyanin and FITC) for Mouse


Record No:47


ACCESS NO100554
GENEIgkc
DESCRIPTIONImmunoglobulin kappa constant
NCBI ENTREZ ACCESS NO16071
UNIPROT ACCESS NOP01837
ORGANISMMouse
DISEASE PHENOTYPEAsthma
SAMPLETissue from bronchial biopsy
TECHNIQUESMicroarray-Affymetrix HG-U95Av2 GeneChips
OMICSGenomics
STUDY High Throughput
COMMENTSdownregulated in allergic asthma (data collected from supplementary table)
GEO_PRIDE_ACCESS_NOGSE15823
REFERENCE15038835
DRUG TARGETBE0003836
MONCLONAL ANTIBODYAnti-Kappa light chain for Human


Record No:48


ACCESS NO100555
GENEIglj3
DESCRIPTIONImmunoglobulin lambda joining 3
NCBI ENTREZ ACCESS NO404740
UNIPROT ACCESS NON/A
ORGANISMMouse
DISEASE PHENOTYPEAsthma
SAMPLETissue from bronchial biopsy
TECHNIQUESMicroarray-Affymetrix HG-U95Av2 GeneChips
OMICSGenomics
STUDY High Throughput
COMMENTSdownregulated in allergic asthma (data collected from supplementary table)
GEO_PRIDE_ACCESS_NOGSE15823
REFERENCE15038835
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:49


ACCESS NO100593
GENEITIH1
DESCRIPTIONInter-alpha-trypsin inhibitor heavy chain H1
NCBI ENTREZ ACCESS NO3697
UNIPROT ACCESS NOP19827
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEBroncho Alveolar Lavage (BAL)F
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSUpregulated after allergen challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:50


ACCESS NO100604
GENEIGHM
DESCRIPTIONimmunoglobulin heavy constant mu
NCBI ENTREZ ACCESS NO3507
UNIPROT ACCESS NOP01871
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEBroncho Alveolar Lavage (BAL)F
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSInvolved in immune response(present in supplimentary table)
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:51


ACCESS NO100609
GENEIFNG
DESCRIPTIONinterferon-gamma
NCBI ENTREZ ACCESS NO3458
UNIPROT ACCESS NOP01579
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLET cells from peripheral blood
TECHNIQUESbisulphite-specific polymerase chain reaction (PCR
OMICSEpigenetics
STUDY Low Throughput
COMMENTSExposure to smoke and ambient air pollution leads to hypermethylation and thereby decreased expression of IFN gamma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23009259
DRUG TARGETBE0000944
MONCLONAL ANTIBODYAnti-IFNGR1 for Human


Record No:52


ACCESS NO100615
GENEIl4
DESCRIPTIONinterleukin 4
NCBI ENTREZ ACCESS NO16189
UNIPROT ACCESS NOP07750
ORGANISMMouse
DISEASE PHENOTYPEAirway Inflammation
SAMPLECD4+ T cell
TECHNIQUESChip assay
OMICSEpigenetics
STUDY Low Throughput
COMMENTSHDAC1 directly controls the gene locus of IL4 and loss of HDAC1 leads to increased IL4.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20702731
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL4 for Human/Mouse/Monkey


Record No:53


ACCESS NO100617
GENEIl13
DESCRIPTIONinterleukin 13
NCBI ENTREZ ACCESS NO16163
UNIPROT ACCESS NOP20109
ORGANISMMouse
DISEASE PHENOTYPEAsthma
SAMPLECD4+ T cell
TECHNIQUESNucleofection with Let-7 miRNA
OMICSEpigenetics
STUDY High Throughput and Low Throughput
COMMENTSIL-13 is regulated by mmu-let-71.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20630862
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:54


ACCESS NO100619
GENEIL2
DESCRIPTIONInterleukin2
NCBI ENTREZ ACCESS NO3558
UNIPROT ACCESS NOP60568
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLECord blood
TECHNIQUESPyrosequencing
OMICSEpigenetics
STUDY Low Throughput
COMMENTSIncreasing methylation in cord blood of a functional CpG site in the IL-2 promoter is associated with increased likelihood of severe asthma exacerbations.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23414538
DRUG TARGETBE0001029
MONCLONAL ANTIBODYAnti-IL2 for Human


Record No:55


ACCESS NO100639
GENEITIH2
DESCRIPTIONInter-alpha (globulin) inhibitor H2
NCBI ENTREZ ACCESS NO3698
UNIPROT ACCESS NOP19823
ORGANISMHuman
DISEASE PHENOTYPESeasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification)
SAMPLENasal fluid
TECHNIQUESQuantitative proteomic analysis through LC/MSMS an
OMICSProteomics
STUDY High Throughput
COMMENTSEnriched in acute phase response pathway.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21887273
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:56


ACCESS NO100651
GENEITIH4
DESCRIPTIONITI heavy chain H4
NCBI ENTREZ ACCESS NO3700
UNIPROT ACCESS NOQ14624
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEPlasma proteins
TECHNIQUESMALDI Tof
OMICSProteomics
STUDY High Throughput
COMMENTSInvolved in coagulation cascade.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21471098
DRUG TARGET
MONCLONAL ANTIBODYAnti-ITIH4 for Human


Record No:57


ACCESS NO100660
GENEIGHA1
DESCRIPTIONIgA
NCBI ENTREZ ACCESS NO3493
UNIPROT ACCESS NOP01876
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEPlasma proteins
TECHNIQUESMALDI Tof
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSUpregulated in asthma compared to control.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21471098
DRUG TARGET
MONCLONAL ANTIBODYAnti-Human IgA for Human


Record No:58


ACCESS NO100661
GENEIGHM
DESCRIPTIONIgM heavy chain
NCBI ENTREZ ACCESS NO3507
UNIPROT ACCESS NOP01871
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEPlasma proteins
TECHNIQUESMALDI Tof
OMICSProteomics
STUDY High Throughput
COMMENTSDownregulated in asthma compared to control.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21471098
DRUG TARGET
MONCLONAL ANTIBODYAnti-Human IgM for Human


Record No:59


ACCESS NO100674
GENEInmt
DESCRIPTIONIndolethylamine N-methyltransferase
NCBI ENTREZ ACCESS NO21743
UNIPROT ACCESS NOP40936
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAsthma induced by Ovalbumin
SAMPLELung tissue
TECHNIQUESMALDI Tof
OMICSProteomics
STUDY High Throughput
COMMENTSDownregulated in chronic asthma model.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21751807
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:60


ACCESS NO100706
GENEICAM-1
DESCRIPTIONintercellular adhesion molecule 1
NCBI ENTREZ ACCESS NO15894
UNIPROT ACCESS NOP13597
ORGANISMTSLP TG mice and BALB/c Mouse
DISEASE PHENOTYPEAcute and chronic asthma
SAMPLEBroncho Alveolar Lavage (BAL) fluid Broncho Alveol
TECHNIQUESLC-MS/MS and Western blot and qRT PCR
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSSignificantly increased in protein but not in mRNA level and involved in adhesion of leukocytes that are chemotaxing.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22837640
DRUG TARGETBE0001085
MONCLONAL ANTIBODYAnti-ICAM1 for Mouse/Human/Rat


Record No:61


ACCESS NO100725
GENEIGHA1
DESCRIPTIONIGHA1 protein
NCBI ENTREZ ACCESS NO3493
UNIPROT ACCESS NO
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEBlood plasma
TECHNIQUESMALDI TOF MS and LC-MS/MS and Western Blot
OMICSProteomics
STUDY High Throughput
COMMENTSDownregulated in atopic dermatitis patients.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19116453
DRUG TARGET
MONCLONAL ANTIBODYAnti-Human IgA for Human


Record No:62


ACCESS NO100749
GENEIfng
DESCRIPTIONInterferon gamma
NCBI ENTREZ ACCESS NO15978
UNIPROT ACCESS NOP01580
ORGANISMbalb C mice
DISEASE PHENOTYPEAllergic asthma after challenge with Aspergillus fumigatus
SAMPLEPeriferal blood monocytes
TECHNIQUESMicroarray (agilent)
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in monocytes from allergic animals.Selected based on fold change.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20840155
DRUG TARGETBE0000944
MONCLONAL ANTIBODYAnti-Interferon gamma for Mouse/Human


Record No:63


ACCESS NO100750
GENEIL1r2
DESCRIPTIONInterleukin-1 receptor
NCBI ENTREZ ACCESS NO16178
UNIPROT ACCESS NOP27931
ORGANISMbalb C mice
DISEASE PHENOTYPEAllergic asthma after challenge with Aspergillus fumigatus
SAMPLEPeriferal blood monocytes
TECHNIQUESMicroarray (agilent)
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in monocytes from allergic animals.Selected based on fold change.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20840155
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL1 Receptor II for Human


Record No:64


ACCESS NO100751
GENEItga4
DESCRIPTIONIntegrin alpha-4
NCBI ENTREZ ACCESS NO16401
UNIPROT ACCESS NOQ00651
ORGANISMbalb C mice
DISEASE PHENOTYPEAllergic asthma after challenge with Aspergillus fumigatus
SAMPLEPeriferal blood monocytes
TECHNIQUESMicroarray (agilent)
OMICSGenomics
STUDY High Throughput
COMMENTSInvolved in cellular adhesion. Downregulated after fungal allergen induction.Selected based on fold change.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20840155
DRUG TARGETBE0000590
MONCLONAL ANTIBODYAnti-Integrin alpha 4 for Rat/Human


Record No:65


ACCESS NO100755
GENEIgfbp1
DESCRIPTIONInsulin-like growth factor binding protein 1
NCBI ENTREZ ACCESS NO16006
UNIPROT ACCESS NOP47876
ORGANISMbalb C mice
DISEASE PHENOTYPEAllergic asthma after challenge with Aspergillus fumigatus
SAMPLEPeriferal blood monocytes
TECHNIQUESMicroarray (agilent)
OMICSGenomics
STUDY High Throughput
COMMENTSDownregulated after allergen challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20840155
DRUG TARGET
MONCLONAL ANTIBODYAnti-IGFBP1 for Mouse/Rat/Human


Record No:66


ACCESS NO100774
GENEIL10
DESCRIPTIONInterleukin 10
NCBI ENTREZ ACCESS NO3586
UNIPROT ACCESS NOP22301
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEDNA
TECHNIQUESIllumina Human Hap 550Kv3 BeadChip SNP array
OMICSGenomics
STUDY High Throughput
COMMENTSInhibits synthesis of IFN gamma and IL2.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19264973
DRUG TARGETBE0002484
MONCLONAL ANTIBODYAnti-IL10 for Mouse/Rat/Human


Record No:67


ACCESS NO100779
GENEINPP4A
DESCRIPTIONInositol polyphosphate-4-phosphatase
NCBI ENTREZ ACCESS NO3631
UNIPROT ACCESS NOQ96PE3
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEDNA
TECHNIQUESIllumina Human Hap 550Kv3 BeadChip SNP array
OMICSGenomics
STUDY High Throughput
COMMENTSrs11676357 SNP is associated with asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19264973
DRUG TARGET
MONCLONAL ANTIBODYAnti-INPP4A for Mouse/Rat/Human


Record No:68


ACCESS NO100784
GENEIRAK3
DESCRIPTIONInterleukin-1 receptor-associated kinase 3
NCBI ENTREZ ACCESS NO11213
UNIPROT ACCESS NOQ9Y616
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEDNA
TECHNIQUESIllumina Human Hap 550Kv3 BeadChip SNP array
OMICSGenomics
STUDY High Throughput
COMMENTSExpressed mainly in the peripheral blood lymphocytes. Rs1152912 SNP is associated with asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19264973
DRUG TARGET
MONCLONAL ANTIBODYAnti-IRAKM for Human


Record No:69


ACCESS NO100787
GENEITGB3
DESCRIPTIONIntegrin beta 3
NCBI ENTREZ ACCESS NO3690
UNIPROT ACCESS NOP05106
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEDNA
TECHNIQUESIllumina Human Hap 550Kv3 BeadChip SNP array
OMICSGenomics
STUDY High Throughput
COMMENTSRisk allele rs11869835 is associated with asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19264973
DRUG TARGETBE0001155
MONCLONAL ANTIBODYAnti-Integrin beta 3 for Mouse/Rat/Human


Record No:70


ACCESS NO100826
GENEIgf1
DESCRIPTIONInsulin like growth fator 1
NCBI ENTREZ ACCESS NO16000
UNIPROT ACCESS NOP05017
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAcute and chronic asthma
SAMPLELung Tissue
TECHNIQUESGeneChip Expression 3 (affymetrix) microarray
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSMore expressed after short term allergen exposure in allergic BALB/c mice.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19028979
DRUG TARGETBE0003418
MONCLONAL ANTIBODYN/A


Record No:71


ACCESS NO100848
GENEIL5
DESCRIPTIONInterleukin-5
NCBI ENTREZ ACCESS NO3567
UNIPROT ACCESS NOP05113
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLECD4+ T cells
TECHNIQUESAffymetrix oligonucleotide microarray and RTPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSTerminal differentiation of B cells to immunoglobulin producing cells.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18269679
DRUG TARGETBE0001208
MONCLONAL ANTIBODYAnti-IL5 for Mouse/Human


Record No:72


ACCESS NO100849
GENEIL4
DESCRIPTIONInterleukin-4
NCBI ENTREZ ACCESS NO3565
UNIPROT ACCESS NOP05112
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLECD4+ T cells
TECHNIQUESAffymetrix oligonucleotide microarray and RTPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSEnhances surface secretion and cell surface excretion of IgE.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18269679
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL4 for Mouse/Human


Record No:73


ACCESS NO100850
GENEIL9
DESCRIPTIONInterleukin-9
NCBI ENTREZ ACCESS NO3578
UNIPROT ACCESS NOP15248
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLECD4+ T cells
TECHNIQUESAffymetrix oligonucleotide microarray and RTPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSUpregulated in subjects from atopic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18269679
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL9 for Mouse/Human


Record No:74


ACCESS NO100852
GENEINHA
DESCRIPTIONInhibin alpha
NCBI ENTREZ ACCESS NO3623
UNIPROT ACCESS NOP05111
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLECD4+ T cells
TECHNIQUESAffymetrix oligonucleotide microarray and RTPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIncreased in CD4+ T cells of asthmatic subjects.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18269679
DRUG TARGET
MONCLONAL ANTIBODYAnti-Inhibin alpha for Mouse/Rat/Human


Record No:75


ACCESS NO100853
GENEIL13
DESCRIPTIONInterleukin-13
NCBI ENTREZ ACCESS NO3596
UNIPROT ACCESS NOP35225
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLECD4+ T cells
TECHNIQUESAffymetrix oligonucleotide microarray and RTPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSOverexpressed in asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18269679
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:76


ACCESS NO100855
GENEIL10
DESCRIPTIONInterleukin-10
NCBI ENTREZ ACCESS NO3586
UNIPROT ACCESS NOP22301
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLECD4+ T cells
TECHNIQUESAffymetrix oligonucleotide microarray and RTPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIncreased in patients suffering from atopic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18269679
DRUG TARGETBE0002484
MONCLONAL ANTIBODYAnti-IL10 for Human


Record No:77


ACCESS NO100856
GENEINHBA
DESCRIPTIONActivin AB alpha polypeptide
NCBI ENTREZ ACCESS NO3624
UNIPROT ACCESS NOP08476
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLECD4+ T cells
TECHNIQUESAffymetrix oligonucleotide microarray and RTPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIncreased in patients suffering from atopic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18269679
DRUG TARGET
MONCLONAL ANTIBODYAnti-Inhibin beta A for Mouse/Rat/Human


Record No:78


ACCESS NO100859
GENEIL12RB2
DESCRIPTIONInterleukin 12 receptor beta 2
NCBI ENTREZ ACCESS NO3595
UNIPROT ACCESS NOQ99665
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLECD4+ T cells
TECHNIQUESAffymetrix oligonucleotide microarray and RTPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSUpregulated in patients suffering from atopic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18269679
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:79


ACCESS NO100903
GENEITGB2
DESCRIPTIONIntegrin beta 2
NCBI ENTREZ ACCESS NO3689
UNIPROT ACCESS NOP05107
ORGANISMHuman
DISEASE PHENOTYPEAllergic sensitization to pollen allergens
SAMPLECD4+ T cells
TECHNIQUESIllumina microarray chips and Genome wide associat
OMICSGenomics
STUDY High Throughput
COMMENTSTriggers neutrophil transmigration in case of lung injury. Downregulated in this study.
GEO_PRIDE_ACCESS_NOGSE18577
REFERENCE24116013
DRUG TARGETBE0001041
MONCLONAL ANTIBODYN/A


Record No:80


ACCESS NO100904
GENEITGAX
DESCRIPTIONIntegrin alpha X
NCBI ENTREZ ACCESS NO3687
UNIPROT ACCESS NOP20702
ORGANISMHuman
DISEASE PHENOTYPEAllergic sensitization to pollen allergens
SAMPLECD4+ T cells
TECHNIQUESIllumina microarray chips and Genome wide associat
OMICSGenomics
STUDY High Throughput
COMMENTSInvolved in the complement system pathway. Downregulated in allergic patients.
GEO_PRIDE_ACCESS_NOGSE18578
REFERENCE24116013
DRUG TARGET
MONCLONAL ANTIBODYAnti-CD11c for Mouse/Rat/Human


Record No:81


ACCESS NO100910
GENEITGAL
DESCRIPTIONIntegrin alpha L
NCBI ENTREZ ACCESS NO3683
UNIPROT ACCESS NOP20701
ORGANISMHuman
DISEASE PHENOTYPEAllergic sensitization to pollen allergens
SAMPLECD4+ T cells
TECHNIQUESIllumina microarray chips and Genome wide associat
OMICSGenomics
STUDY High Throughput
COMMENTS
GEO_PRIDE_ACCESS_NOGSE18584
REFERENCE24116013
DRUG TARGETBE0000516
MONCLONAL ANTIBODYAnti-CD11a for Mouse/Human


Record No:82


ACCESS NO100911
GENEIL17RB
DESCRIPTIONInterleukin 17 receptor B
NCBI ENTREZ ACCESS NO55540
UNIPROT ACCESS NOQ9NRM6
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis
SAMPLEPBMC
TECHNIQUESIllumina Beadarray
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSSignificantly upregulated after pollen allergen exposure in seasonal allergic rhinitis patients.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21252617
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL17B Receptor for Mouse/Human


Record No:83


ACCESS NO100914
GENEIgh6
DESCRIPTIONImmunoglobulin heavy chain complex
NCBI ENTREZ ACCESS NO16019
UNIPROT ACCESS NO
ORGANISMBALB/C mice
DISEASE PHENOTYPEFood allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin
SAMPLEMesenteric lymph node
TECHNIQUEScDNA microarray
OMICSGenomics
STUDY High Throughput
COMMENTSInvolved in humoral immune response.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21211037
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:84


ACCESS NO100915
GENEIgj
DESCRIPTIONImmunoglobulin joining chain
NCBI ENTREZ ACCESS NO16069
UNIPROT ACCESS NOP01592
ORGANISMBALB/C mice
DISEASE PHENOTYPEFood allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin
SAMPLEMesenteric lymph node
TECHNIQUEScDNA microarray and RT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSInvolved in humoral immune response. Downregulated in all three food allergen sensitization
GEO_PRIDE_ACCESS_NON/A
REFERENCE21211037
DRUG TARGET
MONCLONAL ANTIBODYAnti-IGJ for Human


Record No:85


ACCESS NO100924
GENEItgb1
DESCRIPTIONIntegrin beta 1
NCBI ENTREZ ACCESS NO16412
UNIPROT ACCESS NOP09055
ORGANISMBALB/C mice
DISEASE PHENOTYPEFood allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin
SAMPLEMesenteric lymph node
TECHNIQUEScDNA microarray and RT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSUpregulated after beta lactoglobulin induction. Expressed on lymphocytes monocytes eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21211037
DRUG TARGETBE0003575
MONCLONAL ANTIBODYAnti-Integrin beta 1 for Mouse/Rat/Human


Record No:86


ACCESS NO100949
GENEIL7
DESCRIPTIONInterleukin 7
NCBI ENTREZ ACCESS NO3574
UNIPROT ACCESS NOP13232
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEEosinophils from Peripheral blood
TECHNIQUESWestern blotting Flow cytometry ELISA
OMICSOthers
STUDY Low Throughput
COMMENTSFacilitates maturation survival of T cells and activation of eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19155487
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL7 for Human


Record No:87


ACCESS NO100957
GENEIP-10
DESCRIPTIONInhibitory protein 10
NCBI ENTREZ ACCESS NO3627
UNIPROT ACCESS NOP02778
ORGANISMHuman
DISEASE PHENOTYPEAsthma in Obese patients
SAMPLEPeripheral Blood mononuclear cells
TECHNIQUESFlow cytometry and immunoflorescent staining
OMICSOthers
STUDY Low Throughput
COMMENTSCause Inflammation and increased in obese patients compared to non-obese.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23760409
DRUG TARGET
MONCLONAL ANTIBODYAnti-IP10 for Mouse/Human


Record No:88


ACCESS NO100960
GENEITGB3
DESCRIPTIONIntegrin beta 3
NCBI ENTREZ ACCESS NO3690
UNIPROT ACCESS NOP05106
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEDNA from blood
TECHNIQUESGenotyping
OMICSOthers
STUDY Low Throughput
COMMENTSSingle nucleotide polymorphisms in this gene has been significantly associated with asthma in western populations
GEO_PRIDE_ACCESS_NON/A
REFERENCE23451109
DRUG TARGETBE0001155
MONCLONAL ANTIBODYAnti-Integrin beta 3 for Mouse/Rat/Human


Record No:89


ACCESS NO100976
GENEIFNG (IFN- gamma)
DESCRIPTIONInterferon gamma
NCBI ENTREZ ACCESS NO15978
UNIPROT ACCESS NOP01580
ORGANISMMouse
DISEASE PHENOTYPEAllergic diseases and effect of dibutyl phthalate (DBP)
SAMPLEEar tissue
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSThis protein level is significantly elevated after exposure to DBP combined with FITC as compared to saline challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24498391
DRUG TARGETBE0000944
MONCLONAL ANTIBODYN/A


Record No:90


ACCESS NO100977
GENEIl4 (IL-4)
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO16189
UNIPROT ACCESS NOP07750
ORGANISMMouse
DISEASE PHENOTYPEAllergic diseases and effect of dibutyl phthalate (DBP)
SAMPLEEar tissue
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSThis protein level is significantly elevated after exposure to DBP combined with FITC as compared to saline challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24498391
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL4 for Rat


Record No:91


ACCESS NO100978
GENEIl5 (IL-5)
DESCRIPTIONInterleukin 5
NCBI ENTREZ ACCESS NO16191
UNIPROT ACCESS NOP04401
ORGANISMMouse
DISEASE PHENOTYPEAllergic diseases and effect of dibutyl phthalate (DBP)
SAMPLEEar tissue
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSThis protein level is significantly elevated after exposure to DBP combined with FITC as compared to saline challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24498391
DRUG TARGETBE0001208
MONCLONAL ANTIBODYAnti-IL5 for Human


Record No:92


ACCESS NO100979
GENEIl13 (IL-13)
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO16163
UNIPROT ACCESS NOP20109
ORGANISMMouse
DISEASE PHENOTYPEAllergic diseases and effect of dibutyl phthalate (DBP)
SAMPLEEar tissue
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSThis protein level is significantly elevated after exposure to DBP combined with FITC as compared to saline challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24498391
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:93


ACCESS NO100980
GENEIL1A (IL-1A)
DESCRIPTIONInterleukin 1 alpha
NCBI ENTREZ ACCESS NO3552
UNIPROT ACCESS NOP01583
ORGANISMHuman
DISEASE PHENOTYPEOccupational asthma
SAMPLEPrecision-cut lung slices
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSExpression of this pro-inflammatory mediator is significantly increased after exposure to the respiratory sensitizers trimellitic anhydride (TMA) and ammonium hexa chloroplatinate (HClPt) at subtoxic concentrations.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24412833
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL1 alpha for Human


Record No:94


ACCESS NO100982
GENEIL10
DESCRIPTIONInterleukin 10
NCBI ENTREZ ACCESS NO3586
UNIPROT ACCESS NOP22301
ORGANISMHuman
DISEASE PHENOTYPEOccupational asthma
SAMPLEPrecision-cut lung slices
TECHNIQUESMeso Scale Discovery Assays
OMICSOthers
STUDY Low Throughput
COMMENTSIL-10 production was significantly increased (3.0-fold) after exposure to both respiratory allergens TMA and HClPt.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24412833
DRUG TARGETBE00002484
MONCLONAL ANTIBODYAnti-IL10 for Human


Record No:95


ACCESS NO100983
GENEIFNG (IFN- gamma)
DESCRIPTIONInterferon gamma
NCBI ENTREZ ACCESS NO3458
UNIPROT ACCESS NOP01579
ORGANISMHuman
DISEASE PHENOTYPEOccupational asthma
SAMPLEPrecision-cut lung slices
TECHNIQUESMeso Scale Discovery Assays
OMICSOthers
STUDY Low Throughput
COMMENTSThis TH-1 cytokine IFN-γ is significantly induced by HClPt with up to 2810%.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24412833
DRUG TARGETBE0000944
MONCLONAL ANTIBODYN/A


Record No:96


ACCESS NO100984
GENEIL2
DESCRIPTIONInterleukin 2
NCBI ENTREZ ACCESS NO3558
UNIPROT ACCESS NOP60568
ORGANISMHuman
DISEASE PHENOTYPEOccupational asthma
SAMPLEPrecision-cut lung slices
TECHNIQUESMeso Scale Discovery Assays
OMICSOthers
STUDY Low Throughput
COMMENTSThis cytokine is significantly induced by HClPt.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24412833
DRUG TARGETBE0001029
MONCLONAL ANTIBODYAnti-IL2 antibody [AP-MAB0844] for Mouse


Record No:97


ACCESS NO100985
GENEIL13
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO3596
UNIPROT ACCESS NOP35225
ORGANISMHuman
DISEASE PHENOTYPEOccupational asthma
SAMPLEPrecision-cut lung slices
TECHNIQUESMeso Scale Discovery Assays
OMICSOthers
STUDY Low Throughput
COMMENTSThis Th-2 cytokine is significantly induced by HClPt with up to 1320%.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24412833
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:98


ACCESS NO100986
GENEIL5
DESCRIPTIONInterleukin 5
NCBI ENTREZ ACCESS NO3567
UNIPROT ACCESS NOP05113
ORGANISMHuman
DISEASE PHENOTYPEOccupational asthma
SAMPLEPrecision-cut lung slices
TECHNIQUESMeso Scale Discovery Assays
OMICSOthers
STUDY Low Throughput
COMMENTSThis cytokine is significantly induced by HClPt with up to 620%.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24412833
DRUG TARGETBE0001208
MONCLONAL ANTIBODYAnti-IL5 for Human


Record No:99


ACCESS NO100990
GENEIL5
DESCRIPTIONInterleukin 5
NCBI ENTREZ ACCESS NO3567
UNIPROT ACCESS NOP05113
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLENasal lavage fluid
TECHNIQUESLiquichip apparatus (Luminex) with custom designed
OMICSOthers
STUDY Low Throughput
COMMENTSIt is an inflammatory marker of asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24409298
DRUG TARGETBE0001208
MONCLONAL ANTIBODYAnti-IL5 for Human


Record No:100


ACCESS NO100991
GENEIL6
DESCRIPTIONInterleukin 6
NCBI ENTREZ ACCESS NO3569
UNIPROT ACCESS NOP05231
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLENasal lavage fluid
TECHNIQUESLiquichip apparatus (Luminex) with custom designed
OMICSOthers
STUDY Low Throughput
COMMENTSIt is an inflammatory marker of asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24409298
DRUG TARGETBE0000918
MONCLONAL ANTIBODYAnti-IL6 for Rat/Human


Record No:101


ACCESS NO100995
GENEIL1B (IL-1B)
DESCRIPTIONInterleukin 1 beta
NCBI ENTREZ ACCESS NO3553
UNIPROT ACCESS NOP01584
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLENasal lavage fluid
TECHNIQUESLiquichip apparatus (Luminex) with custom designed
OMICSOthers
STUDY Low Throughput
COMMENTSIt is an inflammatory marker of asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24409298
DRUG TARGETBE0001051
MONCLONAL ANTIBODYAnti-IL1B for Human


Record No:102


ACCESS NO101010
GENEIL1B
DESCRIPTIONIL-1 b
NCBI ENTREZ ACCESS NO3553
UNIPROT ACCESS NOP01584
ORGANISMHuman
DISEASE PHENOTYPEAsthma with eosinophilic and neutrophilic inflammation
SAMPLESputum
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt shows highest expression in patients with neutrophilic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24582314
DRUG TARGETBE0001051
MONCLONAL ANTIBODYAnti-IL1B for Human


Record No:103


ACCESS NO101011
GENEIL1R2
DESCRIPTIONIL-1 receptor type II
NCBI ENTREZ ACCESS NO7850
UNIPROT ACCESS NOP27930
ORGANISMHuman
DISEASE PHENOTYPEAsthma with eosinophilic and neutrophilic inflammation
SAMPLESputum
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt shows highest expression in patients with neutrophilic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24582314
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL1 Receptor II for Human


Record No:104


ACCESS NO101012
GENEIL1RN
DESCRIPTIONIL-1 receptor antagonist
NCBI ENTREZ ACCESS NO3557
UNIPROT ACCESS NOP18510
ORGANISMHuman
DISEASE PHENOTYPEAsthma with eosinophilic and neutrophilic inflammation
SAMPLESputum
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt shows highest expression in patients with neutrophilic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24582314
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:105


ACCESS NO101013
GENEIRAK2
DESCRIPTIONIL-1 receptor associated kinase 2
NCBI ENTREZ ACCESS NO3656
UNIPROT ACCESS NOO43187
ORGANISMHuman
DISEASE PHENOTYPEAsthma with eosinophilic and neutrophilic inflammation
SAMPLESputum
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt shows highest expression in patients with neutrophilic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24582314
DRUG TARGETBE0000565
MONCLONAL ANTIBODYAnti-IRAK2 for Mouse/Rat/Human


Record No:106


ACCESS NO101014
GENEISG20
DESCRIPTIONInterferon stimulated exonuclease gene 20kDa
NCBI ENTREZ ACCESS NO3669
UNIPROT ACCESS NOQ96AZ6
ORGANISMHuman
DISEASE PHENOTYPEAsthma with eosinophilic and neutrophilic inflammation
SAMPLESputum
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt shows highest expression in patients with neutrophilic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24582314
DRUG TARGETBE0001938
MONCLONAL ANTIBODYAnti-ISG20 for Human


Record No:107


ACCESS NO101044
GENEIVL
DESCRIPTIONInvolucrin
NCBI ENTREZ ACCESS NO3713
UNIPROT ACCESS NOP07476
ORGANISMHuman
DISEASE PHENOTYPEAtopic eczema (AE)
SAMPLEVernix
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is strongly down regulated in atopic eczema.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24205894
DRUG TARGET
MONCLONAL ANTIBODYAnti-Involucrin for Human


Record No:108


ACCESS NO101055
GENEIL13
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO3596
UNIPROT ACCESS NOP35225
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLESerum
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSTreatment with an anti-IL13 monoclonal antibody Lebrikizumab significantly improves prebronchodilator forced expiratory volume in 1 s (FEV(1)) in a subset of subjects with uncontrolled asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24131304
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:109


ACCESS NO101066
GENEIGHE (IgE)
DESCRIPTIONImmunoglobulin E
NCBI ENTREZ ACCESS NO3497
UNIPROT ACCESS NOP01854
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLESerum
TECHNIQUESIn silico Pubmed database seraching and analysis
OMICSOthers
STUDY Low Throughput
COMMENTSThis serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23952480
DRUG TARGET
MONCLONAL ANTIBODYAnti-IgE [XTE4] for Human


Record No:110


ACCESS NO101068
GENEIL6
DESCRIPTIONInterleukin 6
NCBI ENTREZ ACCESS NO3569
UNIPROT ACCESS NOP05231
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLESerum
TECHNIQUESIn silico Pubmed database seraching and analysis
OMICSOthers
STUDY Low Throughput
COMMENTSThis serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23952480
DRUG TARGETBE0000918
MONCLONAL ANTIBODYAnti-IL6 for Rat/Human


Record No:111


ACCESS NO101070
GENEIL17A (IL17)
DESCRIPTIONInterleukin 17A
NCBI ENTREZ ACCESS NO3605
UNIPROT ACCESS NOQ16552
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLESerum
TECHNIQUESIn silico Pubmed database seraching and analysis
OMICSOthers
STUDY Low Throughput
COMMENTSThis serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23952480
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:112


ACCESS NO101085
GENEIgha (IgA)
DESCRIPTIONImmunoglobulin alpha
NCBI ENTREZ ACCESS NO238447
UNIPROT ACCESS NO
ORGANISMMouse
DISEASE PHENOTYPEAllergic disorder and prebiotics induced tolerance
SAMPLESupernatent of spleen cell cultures
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis protein is highly expressed after allergen sensitization in prebiotic-fed mice. It is related to tolerance and would play a crucial role in the prevention of allergy. Perinatal and postweaning exposure to prebiotics is very encouraging because it allows the induction of several tolerance-related biomarkers
GEO_PRIDE_ACCESS_NON/A
REFERENCE23746232
DRUG TARGET
MONCLONAL ANTIBODYAnti-IgA a for Human


Record No:113


ACCESS NO101086
GENEIghv1-9 (IgG2a)
DESCRIPTIONImmunoglobulin G2A
NCBI ENTREZ ACCESS NO668478
UNIPROT ACCESS NO
ORGANISMMouse
DISEASE PHENOTYPEAllergic disorder and prebiotics induced tolerance
SAMPLESupernatent of spleen cell cultures
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis protein is highly expressed after allergen sensitization in prebiotic-fed mice. It is related to tolerance and would play a crucial role in the prevention of allergy. Perinatal and postweaning exposure to prebiotics is very encouraging because it allows the induction of several tolerance-related biomarkers
GEO_PRIDE_ACCESS_NON/A
REFERENCE23746232
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:114


ACCESS NO101087
GENEIl10 (IL-10)
DESCRIPTIONInterleukin 10
NCBI ENTREZ ACCESS NO16153
UNIPROT ACCESS NOP18893
ORGANISMMouse
DISEASE PHENOTYPEAllergic disorder and prebiotics induced tolerance
SAMPLESupernatent of spleen cell cultures
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis protein is highly expressed after allergen sensitization in prebiotic-fed mice. It is related to tolerance and would play a crucial role in the prevention of allergy. Perinatal and postweaning exposure to prebiotics is very encouraging because it allows the induction of several tolerance-related biomarkers
GEO_PRIDE_ACCESS_NON/A
REFERENCE23746232
DRUG TARGETBE0002484
MONCLONAL ANTIBODYN/A


Record No:115


ACCESS NO101089
GENEIFNG (IFN- gamma)
DESCRIPTIONInterferon gamma
NCBI ENTREZ ACCESS NO15978
UNIPROT ACCESS NOP01580
ORGANISMMouse
DISEASE PHENOTYPEAllergic disorder and prebiotics induced tolerance
SAMPLESupernatent of spleen cell cultures
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis protein is highly expressed after allergen sensitization in prebiotic-fed mice. It is related to tolerance and would play a crucial role in the prevention of allergy. Perinatal and postweaning exposure to prebiotics is very encouraging because it allows the induction of several tolerance-related biomarkers
GEO_PRIDE_ACCESS_NON/A
REFERENCE23746232
DRUG TARGETBE0000944
MONCLONAL ANTIBODYN/A


Record No:116


ACCESS NO101090
GENEIl4 (IL-4)
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO16189
UNIPROT ACCESS NOP07750
ORGANISMMouse
DISEASE PHENOTYPEAllergic disorder and prebiotics induced tolerance
SAMPLESupernatent of spleen cell cultures
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSIt is a biomarker related to allergy and is not affected anyway by allergen challenge followed by prebiotic injestion due to expression of tolerance related biomarkers.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23746232
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL4 for Rat


Record No:117


ACCESS NO101091
GENEIl17a (IL-17a)
DESCRIPTIONInterleukin-17a
NCBI ENTREZ ACCESS NO16171
UNIPROT ACCESS NOQ62386
ORGANISMMouse
DISEASE PHENOTYPEAllergic disorder and prebiotics induced tolerance
SAMPLESupernatent of spleen cell cultures
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSIt is a biomarker related to allergy and is not affected anyway by allergen challenge followed by prebiotic injestion due to expression of tolerance related biomarkers.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23746232
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:118


ACCESS NO101093
GENEIghe (IgE)
DESCRIPTIONImmunoglobulin E
NCBI ENTREZ ACCESS NO380792
UNIPROT ACCESS NOP06336
ORGANISMMouse
DISEASE PHENOTYPEAllergic disorder and prebiotics induced tolerance
SAMPLESupernatent of spleen cell cultures
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSIt is a biomarker related to allergy and is not affected anyway by allergen challenge followed by prebiotic injestion due to expression of tolerance related biomarkers.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23746232
DRUG TARGET
MONCLONAL ANTIBODYAnti-IgE [XTE4] for Human


Record No:119


ACCESS NO101095
GENEICAM1 (sICAM-1)
DESCRIPTIONIntercellular adhesion molecule 1
NCBI ENTREZ ACCESS NO3383
UNIPROT ACCESS NOP0536
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLESerum
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSPatients with shortness in breath can be treated effectively with fluticasone effectively. The effectiveness of treatment can be monitered by significant changes in this biomarker level in serum.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23606983
DRUG TARGETBE0001085
MONCLONAL ANTIBODYAnti-ICAM1 for Rat/Human


Record No:120


ACCESS NO101098
GENEIL6
DESCRIPTIONInterleukin 6
NCBI ENTREZ ACCESS NO3569
UNIPROT ACCESS NOP05231
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLESputum
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSIt is an indicator of exacerbation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23521049
DRUG TARGETBE0000918
MONCLONAL ANTIBODYAnti-IL6 for Rat/Human


Record No:121


ACCESS NO101125
GENEIFNG (IFN- gamma)
DESCRIPTIONInterferon gamma
NCBI ENTREZ ACCESS NO3458
UNIPROT ACCESS NOP01579
ORGANISMHuman
DISEASE PHENOTYPEPediatric asthma and Polycyclic aromatic hydrocarbon exposure
SAMPLEFasting blood
TECHNIQUESMultiplex immunoassay using Luminex 100 system pla
OMICSOthers
STUDY Low Throughput
COMMENTSExposure to polycyclic hydrocarbon has strong association with decrease in serum concentration of this biomarker.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23286340
DRUG TARGETBE0000944
MONCLONAL ANTIBODYN/A


Record No:122


ACCESS NO101126
GENEIL5
DESCRIPTIONInterleukin 5
NCBI ENTREZ ACCESS NO3567
UNIPROT ACCESS NOP05113
ORGANISMHuman
DISEASE PHENOTYPEPediatric asthma and Polycyclic aromatic hydrocarbon exposure
SAMPLEFasting blood
TECHNIQUESMultiplex immunoassay using Luminex 100 system pla
OMICSOthers
STUDY Low Throughput
COMMENTSExposure to polycyclic hydrocarbon has strong association with decrease in serum concentration of this biomarker.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23286340
DRUG TARGETBE0001208
MONCLONAL ANTIBODYAnti-IL5 for Human


Record No:123


ACCESS NO101128
GENEIL10
DESCRIPTIONInterleukin 10
NCBI ENTREZ ACCESS NO3586
UNIPROT ACCESS NOP22301
ORGANISMHuman
DISEASE PHENOTYPEPediatric asthma and Polycyclic aromatic hydrocarbon exposure
SAMPLEFasting blood
TECHNIQUESMultiplex immunoassay using Luminex 100 system pla
OMICSOthers
STUDY Low Throughput
COMMENTSExposure to polycyclic hydrocarbon has strong association with decrease in serum concentration of this biomarker.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23286340
DRUG TARGETBE0002484
MONCLONAL ANTIBODYAnti-IL10 for Human


Record No:124


ACCESS NO101129
GENEIL4 (IL-4)
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO3565
UNIPROT ACCESS NOP05112
ORGANISMHuman
DISEASE PHENOTYPEPediatric asthma and Polycyclic aromatic hydrocarbon exposure
SAMPLEFasting blood
TECHNIQUESMultiplex immunoassay using Luminex 100 system pla
OMICSOthers
STUDY Low Throughput
COMMENTSExposure to polycyclic hydrocarbon has strong association with increase in serum concentration of this biomarker.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23286340
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL4 for Rat


Record No:125


ACCESS NO101140
GENEIL4 (IL-4)
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO3565
UNIPROT ACCESS NOP05112
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of Di-(2-ethylhexyl) phthalate (DEHP)
SAMPLEExtracts of lung tissue
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis inflammatory marker is upregulated upon DHAP exposure.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22701742
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL4 for Rat


Record No:126


ACCESS NO101141
GENEIFNG (IFN-γ)
DESCRIPTIONInterferon gamma
NCBI ENTREZ ACCESS NO3458
UNIPROT ACCESS NOP01579
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of Di-(2-ethylhexyl) phthalate (DEHP)
SAMPLEExtracts of lung tissue
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis inflammatory marker is upregulated upon DHAP exposure.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22701742
DRUG TARGETBE0000944
MONCLONAL ANTIBODYN/A


Record No:127


ACCESS NO101146
GENEIL1B (IL-1B)
DESCRIPTIONInterleukin 1 beta
NCBI ENTREZ ACCESS NO3553
UNIPROT ACCESS NOP01584
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLENasopharyngeal aspirates (NPA)
TECHNIQUESMultiplex immunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSHigher levels of this biomarker is associated with male sex.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22554061
DRUG TARGETBE0001051
MONCLONAL ANTIBODYAnti-IL1B for Human


Record No:128


ACCESS NO101147
GENEIL6
DESCRIPTIONInterleukin 6
NCBI ENTREZ ACCESS NO3569
UNIPROT ACCESS NOP05231
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLENasopharyngeal aspirates (NPA)
TECHNIQUESMultiplex immunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis cytokoine is involved in adaptive immunity.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22554061
DRUG TARGETBE0000918
MONCLONAL ANTIBODYAnti-IL6 for Rat/Human


Record No:129


ACCESS NO101148
GENEIL10
DESCRIPTIONInterleukin 10
NCBI ENTREZ ACCESS NO3586
UNIPROT ACCESS NOP22301
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLENasopharyngeal aspirates (NPA)
TECHNIQUESMultiplex immunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis cytokoine is involved in adaptive immunity.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22554061
DRUG TARGETBE0002484
MONCLONAL ANTIBODYAnti-IL10 for Mouse


Record No:130


ACCESS NO101150
GENEIL7
DESCRIPTIONInterleukin 7
NCBI ENTREZ ACCESS NO3574
UNIPROT ACCESS NOP13232
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLENasopharyngeal aspirates (NPA)
TECHNIQUESMultiplex immunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis cytokoine is involved in adaptive immunity.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22554061
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:131


ACCESS NO101152
GENEIL17A (IL17)
DESCRIPTIONInterleukin 17A
NCBI ENTREZ ACCESS NO3605
UNIPROT ACCESS NOQ16552
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLENasopharyngeal aspirates (NPA)
TECHNIQUESMultiplex immunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis cytokoine is involved in adaptive immunity.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22554061
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:132


ACCESS NO101153
GENEIL13
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO3596
UNIPROT ACCESS NOP35225
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLENasopharyngeal aspirates (NPA)
TECHNIQUESMultiplex immunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis cytokoine is involved in adaptive immunity.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22554061
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:133


ACCESS NO101164
GENEIRF4
DESCRIPTIONInterferon regulatory factor 4
NCBI ENTREZ ACCESS NO3662
UNIPROT ACCESS NOQ15306
ORGANISMHuman
DISEASE PHENOTYPEAllergy and effect of grass pollen immunothrapy
SAMPLEDendritic cell subtypes (DC1/DC2/DC17/DCreg)
TECHNIQUES2D-DIGE and qPCR
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSThis gene was overexpressed after LPS challenge and as well as grass pollen immunotherapy.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22464673
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:134


ACCESS NO101179
GENEIl4 (IL-4)
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO16189
UNIPROT ACCESS NOP07750
ORGANISMMouse
DISEASE PHENOTYPEAsthma and effect of a bioactive flavonol Fisetin
SAMPLEBroncho Alveolar Lavage (BAL)F
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSFisetin dose-dependently inhibited ovalbumin-induced increases in this marker.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22290391
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL4 for Rat


Record No:135


ACCESS NO101180
GENEIl5 (IL-5)
DESCRIPTIONInterleukin 5
NCBI ENTREZ ACCESS NO16191
UNIPROT ACCESS NOP04401
ORGANISMMouse
DISEASE PHENOTYPEAsthma and effect of a bioactive flavonol Fisetin
SAMPLEBroncho Alveolar Lavage (BAL)F
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSFisetin dose-dependently inhibited ovalbumin-induced increases in this marker.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22290391
DRUG TARGETBE0001208
MONCLONAL ANTIBODYAnti-IL5 for Human


Record No:136


ACCESS NO101181
GENEIl13 (IL-13)
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO16163
UNIPROT ACCESS NOP20109
ORGANISMMouse
DISEASE PHENOTYPEAsthma and effect of a bioactive flavonol Fisetin
SAMPLEBroncho Alveolar Lavage (BAL)F
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSFisetin dose-dependently inhibited ovalbumin-induced increases in this marker.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22290391
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:137


ACCESS NO101182
GENEIl17a (IL-17a)
DESCRIPTIONInterleukin-17a
NCBI ENTREZ ACCESS NO16171
UNIPROT ACCESS NOQ62386
ORGANISMMouse
DISEASE PHENOTYPEAsthma and effect of a bioactive flavonol Fisetin
SAMPLELung tissue
TECHNIQUESreal time PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSFisetin attenuated ovalbumin-induced expression of this gene.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22290391
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:138


ACCESS NO101184
GENEIl33
DESCRIPTIONInterleukin 33
NCBI ENTREZ ACCESS NO77125
UNIPROT ACCESS NOQ8BVZ5
ORGANISMMouse
DISEASE PHENOTYPEAsthma and effect of a bioactive flavonol Fisetin
SAMPLELung tissue
TECHNIQUESreal time PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSFisetin attenuated ovalbumin-induced expression of this gene.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22290391
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL33 for Mouse/Human


Record No:139


ACCESS NO101191
GENEIL13
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO3596
UNIPROT ACCESS NOP35225
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEBroncho Alveolar Lavage (BAL) fluid
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSTGF beta activation was also greater in children with severe asthma and was associated with higher IL-13 concentrations.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22206775
DRUG TARGETBE0000984
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:140


ACCESS NO101208
GENEIKZF1
DESCRIPTIONIKAROS zinc finger protein 1
NCBI ENTREZ ACCESS NO10320
UNIPROT ACCESS NOQ13422
ORGANISMHuman
DISEASE PHENOTYPEFood allergy
SAMPLEPeripheral blood mononuclear cells
TECHNIQUES2D-DIGE and MALDI-TOF/TOF and qPCR
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSThis protein was found to be down regulated in RAST+ subjects with severe food allergies.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22091390
DRUG TARGET
MONCLONAL ANTIBODYAnti-Ikaros [SP108] for Human/Rat


Record No:141


ACCESS NO101209
GENEIL17F
DESCRIPTIONInterleukin-17F
NCBI ENTREZ ACCESS NO112744
UNIPROT ACCESS NOQ96PD4
ORGANISMHuman
DISEASE PHENOTYPEFood allergy
SAMPLEPeripheral blood mononuclear cells
TECHNIQUES2D-DIGE and MALDI-TOF/TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein was found to be down regulated in RAST+ subjects with severe food allergies.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22091390
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL17F [4H1629] for Human


Record No:142


ACCESS NO101226
GENEIKZF3
DESCRIPTIONZinc finger protein Aiolos
NCBI ENTREZ ACCESS NO22806
UNIPROT ACCESS NOQ9UKT9
ORGANISMHuman
DISEASE PHENOTYPEFood allergy
SAMPLEPeripheral blood mononuclear cells
TECHNIQUES2D-DIGE and MALDI-TOF/TOF and qPCR
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSThis protein was found to be down regulated in RAST+ subjects with severe food allergies.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22091390
DRUG TARGET
MONCLONAL ANTIBODYAnti-IKZF3 for Human


Record No:143


ACCESS NO101229
GENEIL1B (IL-1B)
DESCRIPTIONInterleukin 1 beta
NCBI ENTREZ ACCESS NO3553
UNIPROT ACCESS NOP01584
ORGANISMHuman
DISEASE PHENOTYPESkin allergy induced by formaldehyde
SAMPLETHP-1 cell line
TECHNIQUESqPCR
OMICSGenomics
STUDY Low Throughput
COMMENTSThis inflammatory marker is upregulated upon bronopol challenge in a time depenent manner.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22034943
DRUG TARGETBE0001051
MONCLONAL ANTIBODYAnti-IL1B for Human


Record No:144


ACCESS NO101234
GENEIL6
DESCRIPTIONInterleukin 6
NCBI ENTREZ ACCESS NO3569
UNIPROT ACCESS NOP05231
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma and obesity related asthma
SAMPLEFasting serum
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis is a Th1 specific biomarker can distinguish obesity asthma from atopic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21980061
DRUG TARGETBE0000918
MONCLONAL ANTIBODYAnti-IL6 for Rat/Human


Record No:145


ACCESS NO101235
GENEIFNG (IFN-γ)
DESCRIPTIONInterferon gamma
NCBI ENTREZ ACCESS NO3458
UNIPROT ACCESS NOP01579
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma and obesity related asthma
SAMPLEFasting serum
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis is a Th1 specific biomarker can distinguish obesity asthma from atopic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21980061
DRUG TARGETBE0000944
MONCLONAL ANTIBODYN/A


Record No:146


ACCESS NO101237
GENEIL4 (IL-4)
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO3565
UNIPROT ACCESS NOP05112
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma and obesity related asthma
SAMPLEFasting serum
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis is a Th2 specific biomarker can distinguish obesity asthma from atopic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21980061
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL4 for Rat


Record No:147


ACCESS NO101238
GENEIL5
DESCRIPTIONInterleukin 5
NCBI ENTREZ ACCESS NO3567
UNIPROT ACCESS NOP05113
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma and obesity related asthma
SAMPLEFasting serum
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis is a Th2 specific biomarker can distinguish obesity asthma from atopic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21980061
DRUG TARGETBE0001208
MONCLONAL ANTIBODYAnti-IL5 for Human


Record No:148


ACCESS NO101239
GENEIL13
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO3596
UNIPROT ACCESS NOP35225
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma and obesity related asthma
SAMPLEFasting serum
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThis is a Th2 specific biomarker can distinguish obesity asthma from atopic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21980061
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:149


ACCESS NO101242
GENEIGHE (IgE)
DESCRIPTIONImmunoglobulin E
NCBI ENTREZ ACCESS NO3497
UNIPROT ACCESS NOP01854
ORGANISMHuman
DISEASE PHENOTYPEAllergy
SAMPLESerum
TECHNIQUESAptamer-based biosensor (apta-biosensor) using CNT
OMICSOthers
STUDY Low Throughput
COMMENTSIn this study the described aptamer-based CNT-FET device enable the production of label-free ultrasensitive electronic biosensors to detect IgE in allergic patients.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21780424
DRUG TARGET
MONCLONAL ANTIBODYAnti-IgE [XTE4] for Human


Record No:150


ACCESS NO101244
GENEIl4 (IL-4)
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO16189
UNIPROT ACCESS NOP07750
ORGANISMMouse
DISEASE PHENOTYPEAsthma and effct of the drug 'Artesunate'
SAMPLELymphocyte
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSArtesunate significantly reduces the level of this Th2 specific inflammatory cytokine induced after ovalbumin challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21695271
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL4 for Rat


Record No:151


ACCESS NO101245
GENEIl5 (IL-5)
DESCRIPTIONInterleukin 5
NCBI ENTREZ ACCESS NO16191
UNIPROT ACCESS NOP04401
ORGANISMMouse
DISEASE PHENOTYPEAsthma and effct of the drug 'Artesunate'
SAMPLELymphocyte
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSArtesunate significantly reduces the level of this Th2 specific inflammatory cytokine induced after ovalbumin challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21695271
DRUG TARGETBE0001208
MONCLONAL ANTIBODYAnti-IL5 for Human


Record No:152


ACCESS NO101246
GENEIl13 (IL-13)
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO16163
UNIPROT ACCESS NOP20109
ORGANISMMouse
DISEASE PHENOTYPEAsthma and effct of the drug 'Artesunate'
SAMPLELymphocyte
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSArtesunate significantly reduces the level of this Th2 specific inflammatory cytokine induced after ovalbumin challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21695271
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:153


ACCESS NO101250
GENEIl17a (IL-17a)
DESCRIPTIONInterleukin-17a
NCBI ENTREZ ACCESS NO16171
UNIPROT ACCESS NOQ62386
ORGANISMMouse
DISEASE PHENOTYPEAsthma and effct of the drug 'Artesunate'
SAMPLELung tissue
TECHNIQUESreal time PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSPretreatment with artesunate (30 mg/kg) demonstrated strong suppression of this cytokine essential for airway inflammation and remodeling.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21695271
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:154


ACCESS NO101251
GENEIl33
DESCRIPTIONInterleukin 33
NCBI ENTREZ ACCESS NO77125
UNIPROT ACCESS NOQ8BVZ5
ORGANISMMouse
DISEASE PHENOTYPEAsthma and effct of the drug 'Artesunate'
SAMPLELung tissue
TECHNIQUESreal time PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSPretreatment with artesunate (30 mg/kg) demonstrated strong suppression of this cytokine essential for airway inflammation and remodeling.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21695271
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL33 for Mouse/Human


Record No:155


ACCESS NO101255
GENEIcam1
DESCRIPTIONIntercellular adhesion molecule 1
NCBI ENTREZ ACCESS NO15894
UNIPROT ACCESS NOP13597
ORGANISMMouse
DISEASE PHENOTYPEAsthma and effct of the drug 'Artesunate'
SAMPLELung tissue
TECHNIQUESreal time PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSPretreatment with artesunate (30 mg/kg) demonstrated strong suppression of this gene that is pivotal for pulmonary recruitment of inflammatory cells like eosinophils and lymphoctyes.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21695271
DRUG TARGETBE0001085
MONCLONAL ANTIBODYAnti-ICAM1 for Rat/Human


Record No:156


ACCESS NO101264
GENEIL6
DESCRIPTIONInterleukin 6
NCBI ENTREZ ACCESS NO3569
UNIPROT ACCESS NOP05231
ORGANISMHuman
DISEASE PHENOTYPESevere and mild asthma
SAMPLESerum
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSThis study suggests that there is not any difference between severe and mild asthma in serum IL-8 and IL-6. Thus level of serum cytokines may not predict severity of asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24024021
DRUG TARGETBE0000918
MONCLONAL ANTIBODYAnti-IL6 for Rat/Human


Record No:157


ACCESS NO101266
GENEIGHE (IgE)
DESCRIPTIONImmunoglobulin E
NCBI ENTREZ ACCESS NO3497
UNIPROT ACCESS NOP01854
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLECord blood
TECHNIQUESPharmacia UniCAP system
OMICSOthers
STUDY Low Throughput
COMMENTSAn elevated cord blood IgE level modestly correlates with elevated total IgE and is associated with a slightly higher likelihood of allergic sensitization among young adults. However cord IgE is not a strong predictor of clinical allergic disorders in this age group.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21354027
DRUG TARGET
MONCLONAL ANTIBODYAnti-IgE [XTE4] for Human


Record No:158


ACCESS NO101275
GENEIL8
DESCRIPTIONInterleukin 8
NCBI ENTREZ ACCESS NO3576
UNIPROT ACCESS NOP10145
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEBlood
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSIncreased expression in rapid onset asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20832159
DRUG TARGETBE0000961
MONCLONAL ANTIBODYAnti-IL8 for Mouse/Human


Record No:159


ACCESS NO101278
GENEIL-4
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO3565
UNIPROT ACCESS NOP05112
ORGANISMHuman
DISEASE PHENOTYPEAsthma (The effect of aspirin desensitization)
SAMPLESputum
TECHNIQUESLINCOplex premixed kit
OMICSOthers
STUDY Low Throughput
COMMENTSDecreased significantly after aspirin treatment.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20728206
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL4 for Rat


Record No:160


ACCESS NO101282
GENEIL4
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO3565
UNIPROT ACCESS NOP05112
ORGANISMHuman
DISEASE PHENOTYPEAllergy (food allergy caused due to milk egg etc)
SAMPLEPeripheral Blood Mononuclear cell.
TECHNIQUESRT PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSSignificantly increased in infants with milk allergy.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20451041
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL4 for Mouse/Human


Record No:161


ACCESS NO101283
GENEIL6
DESCRIPTIONInterleukin 6
NCBI ENTREZ ACCESS NO3569
UNIPROT ACCESS NOQ16552
ORGANISMHuman
DISEASE PHENOTYPEAsthmatic Airways
SAMPLESputum
TECHNIQUESRT PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSPromotes differentiation of CD4+ T cells and is elevated in induced sputum.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20205953
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL6 for Rat/Human


Record No:162


ACCESS NO101284
GENEIL13
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO3596
UNIPROT ACCESS NOP35225
ORGANISMHuman
DISEASE PHENOTYPEAsthmatic Airway
SAMPLESputum
TECHNIQUESRT PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSInvolved in mucus production and is elevated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20205953
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:163


ACCESS NO101285
GENEIL-1 beta
DESCRIPTIONInterleukin 1 Beta
NCBI ENTREZ ACCESS NO3553
UNIPROT ACCESS NOP01584
ORGANISMHuman
DISEASE PHENOTYPEAsthma in children
SAMPLEExhaled Breath condensate
TECHNIQUESMultiplex immunoassay technology
OMICSOthers
STUDY Low Throughput
COMMENTSUpregulated in asthmatic children.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20205697
DRUG TARGETBE0001051
MONCLONAL ANTIBODYAnti-IL1 beta Human


Record No:164


ACCESS NO101286
GENEIL-2
DESCRIPTIONInterleukin 2 receptor alpha
NCBI ENTREZ ACCESS NO3558
UNIPROT ACCESS NOP60568
ORGANISMHuman
DISEASE PHENOTYPEAsthma in children
SAMPLEExhaled Breath condensate
TECHNIQUESMultiplex immunoassay technology
OMICSOthers
STUDY Low Throughput
COMMENTSUpregulated in asthmatic children.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20205697
DRUG TARGETBE0001029
MONCLONAL ANTIBODYAnti-IL2 for Human


Record No:165


ACCESS NO101287
GENEIL-4
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO3565
UNIPROT ACCESS NOP05112
ORGANISMHuman
DISEASE PHENOTYPEAsthma in children
SAMPLEExhaled Breath condensate
TECHNIQUESMultiplex immunoassay technology
OMICSOthers
STUDY Low Throughput
COMMENTSUpregulated in asthmatic children.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20205697
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:166


ACCESS NO101288
GENEIL-6
DESCRIPTIONInterleukin 6
NCBI ENTREZ ACCESS NO3569
UNIPROT ACCESS NOP05231
ORGANISMHuman
DISEASE PHENOTYPEAsthma in children
SAMPLEExhaled Breath condensate
TECHNIQUESMultiplex immunoassay technology
OMICSOthers
STUDY Low Throughput
COMMENTSUpregulated in asthmatic children.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20205697
DRUG TARGETBE0000918
MONCLONAL ANTIBODYN/A


Record No:167


ACCESS NO101289
GENEIL-13
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO3596
UNIPROT ACCESS NOP35225
ORGANISMHuman
DISEASE PHENOTYPEAsthma in children
SAMPLEExhaled Breath condensate
TECHNIQUESMultiplex immunoassay technology
OMICSOthers
STUDY Low Throughput
COMMENTSUpregulated in asthmatic children.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20205697
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:168


ACCESS NO101290
GENEIFN- gamma
DESCRIPTIONInterferon Gamma
NCBI ENTREZ ACCESS NO3458
UNIPROT ACCESS NOP01579
ORGANISMHuman
DISEASE PHENOTYPEAsthma in children
SAMPLEExhaled Breath condensate
TECHNIQUESMultiplex immunoassay technology
OMICSOthers
STUDY Low Throughput
COMMENTSUpregulated in asthmatic children.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20205697
DRUG TARGETBE0000944
MONCLONAL ANTIBODYAnti-Interferon gamma for Mouse/Human


Record No:169


ACCESS NO101297
GENEIP-10
DESCRIPTIONChemokine (C-X-C motif) ligand 10
NCBI ENTREZ ACCESS NO3627
UNIPROT ACCESS NOP02778
ORGANISMHuman
DISEASE PHENOTYPEAsthma in children
SAMPLEExhaled Breath condensate
TECHNIQUESMultiplex immunoassay technology
OMICSOthers
STUDY Low Throughput
COMMENTSUpregulated in asthmatic children.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20205697
DRUG TARGETBE0000934
MONCLONAL ANTIBODYAnti-IP10 for Human


Record No:170


ACCESS NO101304
GENEIL-8
DESCRIPTIONInterleukin-8
NCBI ENTREZ ACCESS NO3576
UNIPROT ACCESS NOP10145
ORGANISMHuman
DISEASE PHENOTYPEChildhood asthma
SAMPLESputum
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSUpregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19788537
DRUG TARGETBE0000961
MONCLONAL ANTIBODYAnti-IL8 for Human/Rabbit/Pig


Record No:171


ACCESS NO101305
GENEIL-5
DESCRIPTIONInterleukin 5
NCBI ENTREZ ACCESS NO3567
UNIPROT ACCESS NOP05113
ORGANISMHuman
DISEASE PHENOTYPEAsthma in teenagers
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESTime resolved flourimetry
OMICSOthers
STUDY Low Throughput
COMMENTSHighly expressed in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19733295
DRUG TARGETBE0001208
MONCLONAL ANTIBODYAnti-IL5 for Mouse/Human


Record No:172


ACCESS NO101306
GENEIL-10
DESCRIPTIONInterleukin 10
NCBI ENTREZ ACCESS NO3586
UNIPROT ACCESS NOP22301
ORGANISMHuman
DISEASE PHENOTYPEAsthma in teenagers
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESTime resolved flourimetry
OMICSOthers
STUDY Low Throughput
COMMENTSA non TH2 cytokine but highly expressed in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19733295
DRUG TARGETBE0002484
MONCLONAL ANTIBODYN/A


Record No:173


ACCESS NO101307
GENEIL-12
DESCRIPTIONInterleukin 12
NCBI ENTREZ ACCESS NON/A
UNIPROT ACCESS NON/A
ORGANISMHuman
DISEASE PHENOTYPEAsthma in teenagers
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESTime resolved flourimetry
OMICSOthers
STUDY Low Throughput
COMMENTSIt plays a key role in Th1 polarization.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19733295
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:174


ACCESS NO101308
GENEIL-13
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO3596
UNIPROT ACCESS NOP35225
ORGANISMHuman
DISEASE PHENOTYPEAsthma in teenagers
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESTime resolved flourimetry
OMICSOthers
STUDY Low Throughput
COMMENTSHighly expressed in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19733295
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human/Rat


Record No:175


ACCESS NO101309
GENEIFN- gamma
DESCRIPTIONInterferon gamma
NCBI ENTREZ ACCESS NO3458
UNIPROT ACCESS NOP01579
ORGANISMHuman
DISEASE PHENOTYPEAsthma in teenagers
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESTime resolved flourimetry
OMICSOthers
STUDY Low Throughput
COMMENTSA non TH2 cytokine but highly expressed in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19733295
DRUG TARGETBE0000944
MONCLONAL ANTIBODYN/A


Record No:176


ACCESS NO101310
GENEIL-4
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO3565
UNIPROT ACCESS NOP05112
ORGANISMHuman
DISEASE PHENOTYPEAsthma in teenagers
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESRT-PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSIncreased expression in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19733295
DRUG TARGET
MONCLONAL ANTIBODYAnti IL4 for Human


Record No:177


ACCESS NO101312
GENEIL8
DESCRIPTIONInterleukin-8
NCBI ENTREZ ACCESS NO3576
UNIPROT ACCESS NOP10145
ORGANISMHuman
DISEASE PHENOTYPESevere and non severe asthma
SAMPLESputum
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSDid not show any marked expression change in severe and non severe asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19622091
DRUG TARGETBE0000961
MONCLONAL ANTIBODYN/A


Record No:178


ACCESS NO101313
GENEIL13
DESCRIPTIONInterleukin-13
NCBI ENTREZ ACCESS NO3596
UNIPROT ACCESS NOP35225
ORGANISMHuman
DISEASE PHENOTYPESevere and non severe asthma
SAMPLESputum
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSDid not show any marked expression change in severe and non severe asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19622091
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human/Rat


Record No:179


ACCESS NO101326
GENEIL1RN
DESCRIPTIONInterleukin 1 receptor antagonist isoform
NCBI ENTREZ ACCESS NO3557
UNIPROT ACCESS NOP18510
ORGANISMHuman
DISEASE PHENOTYPEAllergy(Comparison of Dendritic cell proteome in atopic and non atopic patients)
SAMPLEDendritic cell
TECHNIQUESMALDI Tof/Tof
OMICSProteomics
STUDY High Throughput
COMMENTSInvolved in Immune response.Differentially expressed in atopic individuals after administering active and inactive DerP1.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19494521
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:180


ACCESS NO101339
GENEiNOS
DESCRIPTIONNitric oxide synthase 2 inducible
NCBI ENTREZ ACCESS NO18126
UNIPROT ACCESS NOP29477
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAsthma (Effect of andrographolide on NF kappa beta pathway in asthma)
SAMPLEBronchial Epithelial cells
TECHNIQUESRT-PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSStrongly downregulated after andrographolide treatment.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19201922
DRUG TARGETBE0000005
MONCLONAL ANTIBODYAnti-iNOS for Mouse/Human


Record No:181


ACCESS NO101340
GENEIL-6
DESCRIPTIONInterleukin 6
NCBI ENTREZ ACCESS NO16193
UNIPROT ACCESS NOP08505
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAsthma (Effect of andrographolide on NF kappa beta pathway in asthma)
SAMPLEBronchial Epithelial cells
TECHNIQUESRT-PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSAndrographolide blocked the upregulation of IL6.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19201922
DRUG TARGETBE0000918
MONCLONAL ANTIBODYN/A


Record No:182


ACCESS NO101341
GENEIL-8
DESCRIPTIONInterleukin 8
NCBI ENTREZ ACCESS NO3576
UNIPROT ACCESS NOP10145
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAsthma (Effect of andrographolide on NF kappa beta pathway in asthma)
SAMPLEBronchial Epithelial cells
TECHNIQUESRT-PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSAndrographolide blocked the upregulation of IL8.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19201922
DRUG TARGETBE0000961
MONCLONAL ANTIBODYAnti-IL8 for Human/Pig


Record No:183


ACCESS NO101343
GENEIL-4
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO16189
UNIPROT ACCESS NOP07750
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAsthma (Effect of andrographolide on NF kappa beta pathway in asthma)
SAMPLEThoracic Lymph node cells
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSExpression lowered after Andrographolide treatment.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19201922
DRUG TARGET
MONCLONAL ANTIBODYAnti IL4 for Human


Record No:184


ACCESS NO101344
GENEIL-5
DESCRIPTIONInterleukin 5
NCBI ENTREZ ACCESS NO16191
UNIPROT ACCESS NOP04401
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAsthma (Effect of andrographolide on NF kappa beta pathway in asthma)
SAMPLEThoracic Lymph node cells
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSExpression lowered after Andrographolide treatment.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19201922
DRUG TARGETBE0001208
MONCLONAL ANTIBODYAnti-IL5 for Mouse/Human


Record No:185


ACCESS NO101345
GENEIL-13
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO16163
UNIPROT ACCESS NOP20109
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAsthma (Effect of andrographolide on NF kappa beta pathway in asthma)
SAMPLEThoracic Lymph node cells
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSExpression lowered after Andrographolide treatment.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19201922
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Mouse


Record No:186


ACCESS NO101347
GENEIFN- gamma
DESCRIPTIONInterferon gamma
NCBI ENTREZ ACCESS NO15978
UNIPROT ACCESS NOP01580
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAsthma (Effect of andrographolide on NF kappa beta pathway in asthma)
SAMPLEThoracic Lymph node cells
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSExpression increased after Andrographolide treatment.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19201922
DRUG TARGETBE0000944
MONCLONAL ANTIBODYAnti-Interferon gamma for Mouse/Human


Record No:187


ACCESS NO101360
GENEIgG1
DESCRIPTIONImmunoglobulin heavy chain 4 protein
NCBI ENTREZ ACCESS NO16017
UNIPROT ACCESS NOQ5F2I1
ORGANISMMouse
DISEASE PHENOTYPEChronic Asthma
SAMPLELung Tissue and Broncho Alveolar Lavage (BAL) flui
TECHNIQUESMALDI Tof/Tof
OMICSProteomics
STUDY High Throughput
COMMENTSUpregulated in Chronic asthma. Indicates hyperplasia of mucous glands.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18594147
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:188


ACCESS NO101409
GENEIl4i1
DESCRIPTIONInterleukin 4 induced 1
NCBI ENTREZ ACCESS NO14204
UNIPROT ACCESS NOO09046
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSOverexpressed after 3hours and 12 hours of allergenic mould extract challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGETBE0004566
MONCLONAL ANTIBODYN/A


Record No:189


ACCESS NO101411
GENEIl1rn
DESCRIPTIONInterleukin 1 receptor antagonist
NCBI ENTREZ ACCESS NO16181
UNIPROT ACCESS NOP25085
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSOverexpressed after 3hours and 12 hours of allergenic mould extract challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL1RA for Mouse/Rat/Human


Record No:190


ACCESS NO101419
GENEIl1b
DESCRIPTIONInterleukin 1 beta
NCBI ENTREZ ACCESS NO16176
UNIPROT ACCESS NOP10749
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSOverexpressed after 3hours and 12 hours of allergenic mould extract challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGETBE0001051
MONCLONAL ANTIBODYAnti-IL1 beta for Mouse


Record No:191


ACCESS NO101426
GENEIgsf6
DESCRIPTIONImmunoglobulin superfamily member 6
NCBI ENTREZ ACCESS NO80719
UNIPROT ACCESS NOP0C6B7
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSOverexpressed after 3hours and 12 hours of allergenic mould extract challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-IGSF6 for Human


Record No:192


ACCESS NO101430
GENEIl1r2
DESCRIPTIONInterleukin 1 receptor type II
NCBI ENTREZ ACCESS NO16178
UNIPROT ACCESS NOP27931
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSOverexpressed after 3hours and 12 hours of allergenic mould extract challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:193


ACCESS NO101450
GENEItgam
DESCRIPTIONIntegrin alpha M
NCBI ENTREZ ACCESS NO16409
UNIPROT ACCESS NOE9Q604
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3hours and 12 hours of allergen induction in asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-CD11b for Mouse/Rabbit/Human


Record No:194


ACCESS NO101459
GENEIkbke
DESCRIPTIONInhibitor of kappaB kinase epsilon
NCBI ENTREZ ACCESS NO56489
UNIPROT ACCESS NOQ9R0T8
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3 and 12 hours of fungal allergen induction in asthmatic mice.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-IKKi/IKKe for Human


Record No:195


ACCESS NO101462
GENEIfit1
DESCRIPTIONInterferon-induced protein with tetratricopeptide repeats 1
NCBI ENTREZ ACCESS NO15957
UNIPROT ACCESS NOQ64282
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSOverexpressed after 3hours and 12 hours of allergenic mould extract challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-IFIT1 for Human


Record No:196


ACCESS NO101480
GENEIl1f9
DESCRIPTIONInterleukin 1 family member 9
NCBI ENTREZ ACCESS NO215257
UNIPROT ACCESS NOQ3U0P4
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3 and 12 hours of fungal allergen challenge in asthmatic mice.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL36 gamma for Human


Record No:197


ACCESS NO101485
GENEIl17ra
DESCRIPTIONInterleukin-17 receptor A precursor
NCBI ENTREZ ACCESS NO16172
UNIPROT ACCESS NOQ60943
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSExpressed in allergen induced asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL17A Receptor for Mouse/Human


Record No:198


ACCESS NO101501
GENEIrf5
DESCRIPTIONInterferon regulatory factor 5
NCBI ENTREZ ACCESS NO27056
UNIPROT ACCESS NOP56477
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3 and 12 hours of allergen induction in asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-IRF5 for mouse/Human


Record No:199


ACCESS NO101517
GENEIrf4
DESCRIPTIONInterferon regulatory factor 4
NCBI ENTREZ ACCESS NO16364
UNIPROT ACCESS NOQ9QUI6
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3 and 12 hours of allergen induction in asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-MUM1 for Human


Record No:200


ACCESS NO101535
GENEIFN-gamma
DESCRIPTIONInterferon gamma
NCBI ENTREZ ACCESS NO3458
UNIPROT ACCESS NOP01579
ORGANISMHuman
DISEASE PHENOTYPEChildhood asthma
SAMPLEExhaled breath condensate
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSHas pro inflammatory effects and is responsible for recruiting infammatory cytokines . Higher expression in asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17845410
DRUG TARGETBE0000944
MONCLONAL ANTIBODYAnti-Interferon gamma for Human


Record No:201


ACCESS NO101536
GENEIL-4
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO3565
UNIPROT ACCESS NOP05112
ORGANISMHuman
DISEASE PHENOTYPEChildhood asthma
SAMPLEExhaled breath condensate
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSHigher expression in asthmatics compared to controls.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17845410
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:202


ACCESS NO101537
GENEIP-10
DESCRIPTIONInduced Protein 10
NCBI ENTREZ ACCESS NO3627
UNIPROT ACCESS NOP02778
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by Virus
SAMPLEBronchial epithelial cells
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSHighly expressed in virus induced asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17628646
DRUG TARGETBE0000934
MONCLONAL ANTIBODYAnti-IP10 for Mouse/Human


Record No:203


ACCESS NO101539
GENEIL-6
DESCRIPTIONInterleukin 6
NCBI ENTREZ ACCESS NO3569
UNIPROT ACCESS NOP05231
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by Virus
SAMPLEBronchial epithelial cells
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSExpressed in virus induced asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17628646
DRUG TARGETBE0000918
MONCLONAL ANTIBODYN/A


Record No:204


ACCESS NO101540
GENEIL-8(CXCL8)
DESCRIPTIONInterleukin 8
NCBI ENTREZ ACCESS NO3576
UNIPROT ACCESS NOP10145
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by Virus
SAMPLEBronchial epithelial cells
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSExpressed in virus induced asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17628646
DRUG TARGETBE0000961
MONCLONAL ANTIBODYAnti-IL8 for Human/Pig


Record No:205


ACCESS NO101544
GENEIcam-1
DESCRIPTIONIntercellular adhesion molecule 1
NCBI ENTREZ ACCESS NO15894
UNIPROT ACCESS NOP13597
ORGANISMFemale Balb/c Mice
DISEASE PHENOTYPEAsthma(Effect of Glycogen synthase kinase-3 beta inhibition on asthma)
SAMPLELung tissue
TECHNIQUESRT-PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSSignificantly upregulated after OVA challenge in mRNA. However decreased after Gsk-3b inhibitor induction.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17556716
DRUG TARGETBE0001085
MONCLONAL ANTIBODYAnti-ICAM1 for Human


Record No:206


ACCESS NO101549
GENEIL-6
DESCRIPTIONInterleukin 6
NCBI ENTREZ ACCESS NO16193
UNIPROT ACCESS NOP08505
ORGANISMFemale Balb/c Mice
DISEASE PHENOTYPEAsthma(Effect of Glycogen synthase kinase-3 beta inhibition on asthma)
SAMPLELung tissue
TECHNIQUESRT-PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSGsk3b inhibitor blocked the expression of IL6.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17556716
DRUG TARGETBE0000918
MONCLONAL ANTIBODYN/A


Record No:207


ACCESS NO101550
GENEIL-8
DESCRIPTIONChemokine (C-X-C motif) ligand 15
NCBI ENTREZ ACCESS NO20309
UNIPROT ACCESS NOQ9WVL7
ORGANISMFemale Balb/c Mice
DISEASE PHENOTYPEAsthma(Effect of Glycogen synthase kinase-3 beta inhibition on asthma)
SAMPLELung tissue
TECHNIQUESRT-PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSGsk3b inhibitor blocked the expression of IL8.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17556716
DRUG TARGETBE0000961
MONCLONAL ANTIBODYAnti-IL8 for Human/Pig


Record No:208


ACCESS NO101645
GENEIFNGR1
DESCRIPTION IFN-g receptor 1
NCBI ENTREZ ACCESS NO3459
UNIPROT ACCESS NOP15260
ORGANISMHuman
DISEASE PHENOTYPEInsect allergy(Bee venom immunotherapy)
SAMPLEPeripheral Blood Mononuclear cells
TECHNIQUESGene chip microarray and RT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSInvolved in osteopontin regulatory pathway. Expressed after venom immunotherapy.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15867867
DRUG TARGETBE0000711
MONCLONAL ANTIBODYAnti-IFNGR1 for Human


Record No:209


ACCESS NO101651
GENEInmt
DESCRIPTIONThioether S-methyltransferase
NCBI ENTREZ ACCESS NO21743
UNIPROT ACCESS NOP40936
ORGANISMMale BALB/c mice
DISEASE PHENOTYPEAllergic asthma
SAMPLELung tissue
TECHNIQUES2D electrophoresis and MALDI Tof Tof
OMICSProteomics
STUDY High Throughput
COMMENTSDownregulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE16100447
DRUG TARGET
MONCLONAL ANTIBODYAnti-INMT for Mouse/Rat/Human


Record No:210


ACCESS NO101662
GENEIL-6
DESCRIPTIONInterleukin 6
NCBI ENTREZ ACCESS NO3569
UNIPROT ACCESS NOP05231
ORGANISMHuman
DISEASE PHENOTYPEAllergy (Perinatal immune responses)
SAMPLEPBMC
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSNeonatal responses were lower for children positive to Fel d1.
GEO_PRIDE_ACCESS_NON/A
REFERENCE14616132
DRUG TARGETBE0000918
MONCLONAL ANTIBODYN/A


Record No:211


ACCESS NO101663
GENEIL-13
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO3596
UNIPROT ACCESS NOP35225
ORGANISMHuman
DISEASE PHENOTYPEAllergy (Perinatal immune responses)
SAMPLEPBMC
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSLower expression in children at birth who show positive SPT to house dust mite.
GEO_PRIDE_ACCESS_NON/A
REFERENCE14616132
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:212


ACCESS NO101664
GENEIFN- gamma
DESCRIPTIONInterferon gamma
NCBI ENTREZ ACCESS NO3458
UNIPROT ACCESS NOP01579
ORGANISMHuman
DISEASE PHENOTYPEAllergy (Perinatal immune responses)
SAMPLEPBMC
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSWeaker IFN gamma response in neonatal patients having a history to allergy.
GEO_PRIDE_ACCESS_NON/A
REFERENCE14616132
DRUG TARGETBE0000944
MONCLONAL ANTIBODYAnti-Interferon gamma for Human


Record No:213


ACCESS NO101665
GENEIL-5
DESCRIPTIONInterleukin 5
NCBI ENTREZ ACCESS NO3567
UNIPROT ACCESS NOP05113
ORGANISMHuman
DISEASE PHENOTYPEAllergy (Perinatal immune responses)
SAMPLEPBMC
TECHNIQUESRT-PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSDownregulated in children having no family history of allergy and upregulated in children having family history of allergy.
GEO_PRIDE_ACCESS_NON/A
REFERENCE14616132
DRUG TARGETBE0001208
MONCLONAL ANTIBODYAnti-IL5 for Human


Record No:214


ACCESS NO101670
GENEIcam1 (ICAM-1)
DESCRIPTIONIntercellular adhesion molecule 1
NCBI ENTREZ ACCESS NO15894
UNIPROT ACCESS NOP13597
ORGANISMMouse
DISEASE PHENOTYPEAsthma and its modulation by Minocycline
SAMPLELung cells
TECHNIQUESReal time PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSMinocycline marked reduction in the expression of this NF kappa Beta dependent gene.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23184953
DRUG TARGETBE0001085
MONCLONAL ANTIBODYAnti-ICAM1 [MEM-111] for rat/Human


Record No:215


ACCESS NO101675
GENEIgfbp3 (IGFBP-3)
DESCRIPTIONInsulin-like growth factor binding protein 3
NCBI ENTREZ ACCESS NO16009
UNIPROT ACCESS NOP47878
ORGANISMMouse
DISEASE PHENOTYPEAsthma and its protection by IGFBP-3 treatment
SAMPLELung tissue and Broncho Alveolar Lavage (BAL) flui
TECHNIQUESImmunoblot and immunohistochemistry
OMICSProteomics
STUDY Low Throughput
COMMENTSThis protein was found to be down regulated significantly upon ovalbumin challenge. IGFBP-3 treatment inhibits airway inflammation and hyper-responsiveness via an IGF-independent mechanism that involves activation of IGFBP-3R signaling and cross-talk with NF- B signaling.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21383009
DRUG TARGETBE0000970
MONCLONAL ANTIBODYAnti-IGFBP3 for Human


Record No:216


ACCESS NO101676
GENEIcam1 (ICAM-1)
DESCRIPTIONIntercellular adhesion molecule 1
NCBI ENTREZ ACCESS NO15894
UNIPROT ACCESS NOP13597
ORGANISMMouse
DISEASE PHENOTYPEAsthma and its protection by IGFBP-3 treatment
SAMPLELung tissue and Broncho Alveolar Lavage (BAL) flui
TECHNIQUESImmunoblot
OMICSProteomics
STUDY Low Throughput
COMMENTSIGFBP-3 treatment blocks TNF- alpha induced ICAM-1 expression in NF-kappa B signaling cascades upon allergen challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21383009
DRUG TARGETBE0001085
MONCLONAL ANTIBODYAnti-ICAM1 [MEM-111] for rat/Human


Record No:217


ACCESS NO101679
GENEIl4 (IL-4)
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO16189
UNIPROT ACCESS NOP07750
ORGANISMMouse
DISEASE PHENOTYPEAsthma and its protection by IGFBP-3 treatment
SAMPLELung tissue and Broncho Alveolar Lavage (BAL) flui
TECHNIQUESImmunoblot and ELISA
OMICSProteomics
STUDY Low Throughput
COMMENTSThis proinflammatory protein is upregulated in lung tissue upon allergen challenge. However in IGFBP-3 transgenic mice this protein is significantly down regulated even after allergen challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21383009
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL4 [MP4-25D2] for human


Record No:218


ACCESS NO101680
GENEIl5 (IL-5)
DESCRIPTIONInterleukin 5
NCBI ENTREZ ACCESS NO16191
UNIPROT ACCESS NOP04401
ORGANISMMouse
DISEASE PHENOTYPEAsthma and its protection by IGFBP-3 treatment
SAMPLELung tissue and Broncho Alveolar Lavage (BAL) flui
TECHNIQUESImmunoblot and ELISA
OMICSProteomics
STUDY Low Throughput
COMMENTSThis proinflammatory protein is upregulated in lung tissue upon allergen challenge. However in IGFBP-3 transgenic mice this protein is significantly down regulated even after allergen challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21383009
DRUG TARGETBE0001208
MONCLONAL ANTIBODYAnti-IL5 [JES1-39D10] for Human


Record No:219


ACCESS NO101681
GENEIl13 (IL-13)
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO16163
UNIPROT ACCESS NOP20109
ORGANISMMouse
DISEASE PHENOTYPEAsthma and its protection by IGFBP-3 treatment
SAMPLELung tissue and Broncho Alveolar Lavage (BAL) flui
TECHNIQUESImmunoblot and ELISA
OMICSProteomics
STUDY Low Throughput
COMMENTSThis proinflammatory protein is upregulated in lung tissue upon allergen challenge. However in IGFBP-3 transgenic mice this protein is significantly down regulated even after allergen challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21383009
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 [JES10-5A2] for Human


Record No:220


ACCESS NO101698
GENEIGFBP2
DESCRIPTIONInsulin-like growth factor-binding protein 2
NCBI ENTREZ ACCESS NO3485
UNIPROT ACCESS NOP18065
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis growth factor is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-IGFBP2 [EPR3380(2)] for human


Record No:221


ACCESS NO101699
GENEIGFBP3
DESCRIPTIONInsulin-like growth factor-binding protein 3
NCBI ENTREZ ACCESS NO3486
UNIPROT ACCESS NOP17936
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis growth factor is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0000970
MONCLONAL ANTIBODYAnti-IGFBP3 for Human


Record No:222


ACCESS NO101703
GENEIGFBP6
DESCRIPTIONInsulin-like growth factor-binding protein 6
NCBI ENTREZ ACCESS NO3489
UNIPROT ACCESS NOP24592
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis growth factor is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-IGFBP6 for Human


Record No:223


ACCESS NO101719
GENEITIH1
DESCRIPTIONInter-alpha-trypsin inhibitor heavy chain H1
NCBI ENTREZ ACCESS NO3697
UNIPROT ACCESS NOP19827
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protease inhibitor is upregulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:224


ACCESS NO101726
GENEITIH3
DESCRIPTIONInter-alpha-trypsin inhibitor heavy chain 3
NCBI ENTREZ ACCESS NO3699
UNIPROT ACCESS NOQ06033
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protease inhibitor is upregulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:225


ACCESS NO101767
GENEITLN1
DESCRIPTIONIntelectin (endothelial lectin HL-1)
NCBI ENTREZ ACCESS NO55600
UNIPROT ACCESS NOQ8WWA0
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis local matrix protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-ITLN1 for Human


Record No:226


ACCESS NO101846
GENEIGJ
DESCRIPTIONImmunoglobulin J chain/IGJ
NCBI ENTREZ ACCESS NO3512
UNIPROT ACCESS NOP01591
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis
SAMPLENasal mucus
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSIt showed 0.7 fold expression change in rhinitis patients.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24290289
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:227


ACCESS NO101911
GENEIDE
DESCRIPTIONInsulin-degrading enzyme
NCBI ENTREZ ACCESS NO3416
UNIPROT ACCESS NOP14735
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPeripheral blood eosinophils
TECHNIQUES2DE-PAGE and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic dermatitis patients eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15832365
DRUG TARGETBE0001183
MONCLONAL ANTIBODYAnti-Insulin degrading enzyme / IDE for Human


Record No:228


ACCESS NO101915
GENEITGA6
DESCRIPTIONIntegrin a-6 precursor
NCBI ENTREZ ACCESS NO3655
UNIPROT ACCESS NOP23229
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPeripheral blood eosinophils
TECHNIQUES2DE-PAGE and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic dermatitis patients eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15832365
DRUG TARGET
MONCLONAL ANTIBODYAnti-Integrin alpha 6 for Human


Record No:229


ACCESS NO101933
GENEITGB7
DESCRIPTIONIntegrin b-7
NCBI ENTREZ ACCESS NO3695
UNIPROT ACCESS NOP26010
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPeripheral blood eosinophils
TECHNIQUES2DE-PAGE and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic dermatitis patients eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15832365
DRUG TARGETBE0003414
MONCLONAL ANTIBODYAnti-Integrin beta 7 for Mouse/Human


Record No:230


ACCESS NO101956
GENEIBRDC3
DESCRIPTIONIBR domain containing 3
NCBI ENTREZ ACCESS NO127544
UNIPROT ACCESS NOQ6ZMZ0
ORGANISMHuman(Asthmatic children)
DISEASE PHENOTYPEAsthma( Mite sensitized asthma)
SAMPLEPeripheral Blood Mononuclear Cells
TECHNIQUESMicroarray and RT-PCR
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in asthmatic children.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19187333
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:231


ACCESS NO101963
GENEIGF2BP2
DESCRIPTIONInsulin-like growth factor 2 mRNA binding protein 2
NCBI ENTREZ ACCESS NO10644
UNIPROT ACCESS NOQ9Y6M1
ORGANISMHuman(Asthmatic children)
DISEASE PHENOTYPEAsthma( Mite sensitized asthma)
SAMPLEPeripheral Blood Mononuclear Cells
TECHNIQUESMicroarray and RT-PCR
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in asthmatic children. Involved in immune and lymphatic system development.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19187333
DRUG TARGET
MONCLONAL ANTIBODYAnti-IGF2BP2 for Mouse/Rat/Human


Record No:232


ACCESS NO101969
GENEIFN- gamma (IFNG)
DESCRIPTIONInterferon gamma
NCBI ENTREZ ACCESS NO3458
UNIPROT ACCESS NOP01579
ORGANISMHuman
DISEASE PHENOTYPEAllergy (Immunotherapy of pollen allergy)
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESFlow cytometry
OMICSOthers
STUDY Low Throughput
COMMENTSIncreased after specific immunotherapy.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24834772
DRUG TARGETBE0000944
MONCLONAL ANTIBODYAnti-Interferon gamma for Mouse/Rat/Human


Record No:233


ACCESS NO101970
GENEIL-10
DESCRIPTIONInterleukin 10
NCBI ENTREZ ACCESS NO3586
UNIPROT ACCESS NOP22301
ORGANISMHuman
DISEASE PHENOTYPEAllergy (Immunotherapy of pollen allergy)
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESFlow cytometry
OMICSOthers
STUDY Low Throughput
COMMENTSIncreased after specific immunotherapy.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24834772
DRUG TARGETBE0002484
MONCLONAL ANTIBODYN/A


Record No:234


ACCESS NO101992
GENEIQCG
DESCRIPTIONIQ motif containing G
NCBI ENTREZ ACCESS NO84223
UNIPROT ACCESS NOQ9H095
ORGANISMHuman
DISEASE PHENOTYPEAsthma and allergic rhinitis
SAMPLEEpithelial cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in patients with allergic rhinitis in the upper airways.
GEO_PRIDE_ACCESS_NOGSE51392
REFERENCE24475887
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:235


ACCESS NO102019
GENEIL13RA2
DESCRIPTIONInterleukin 13 receptor alpha 2
NCBI ENTREZ ACCESS NO3598
UNIPROT ACCESS NOQ14627
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis and asthma
SAMPLEPrimary nasal and bronchial epithelial cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSUpregulated in upper airways in allergic rhinitis patients with or without asthma.(Data in supplimentary table).
GEO_PRIDE_ACCESS_NOGSE44037
REFERENCE24282527
DRUG TARGETBE0002421
MONCLONAL ANTIBODYAnti-IL13 receptor alpha 2 for Rabbit/Human


Record No:236


ACCESS NO102020
GENEIL1B
DESCRIPTIONInterleukin 1 beta
NCBI ENTREZ ACCESS NO3553
UNIPROT ACCESS NOP01584
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis and asthma
SAMPLEPrimary nasal and bronchial epithelial cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSUpregulated in upperairways of allergic rhinitis patients without asthma and downregulated in upper airways of patients with asthma. (Data in supplimentary table.)
GEO_PRIDE_ACCESS_NOGSE44037
REFERENCE24282527
DRUG TARGETBE0001051
MONCLONAL ANTIBODYAnti-IL1 beta for Human


Record No:237


ACCESS NO102021
GENEIL8(CXCL8)
DESCRIPTIONChemokine (C-X-C motif) ligand 8
NCBI ENTREZ ACCESS NO3576
UNIPROT ACCESS NOP10145
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis and asthma
SAMPLEPrimary nasal and bronchial epithelial cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSDownregulated in upperairways of patients with allergic rhinitis and asthma.(Data in supplimentary table.)
GEO_PRIDE_ACCESS_NOGSE44037
REFERENCE24282527
DRUG TARGETBE0000961
MONCLONAL ANTIBODYAnti-IL8 for Mouse/Human


Record No:238


ACCESS NO102034
GENEIL33
DESCRIPTIONInterleukin 33
NCBI ENTREZ ACCESS NO90865
UNIPROT ACCESS NOO95760
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis and asthma
SAMPLEBronchial epithelial cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput
COMMENTSHighly expressed in patients with allergic rhinitis and asthma. Induces Th2 associated cytokines.(Data in supplimentary table).
GEO_PRIDE_ACCESS_NOGSE44037
REFERENCE24282527
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL33 for Mouse/Human


Record No:239


ACCESS NO102055
GENEIL13RA2
DESCRIPTIONInterleukin 13 receptor alpha 2
NCBI ENTREZ ACCESS NO3598
UNIPROT ACCESS NOQ14627
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis and asthma
SAMPLENasal epithelial cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput
COMMENTSHighly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table).
GEO_PRIDE_ACCESS_NOGSE44037
REFERENCE24282527
DRUG TARGETBE0002421
MONCLONAL ANTIBODYN/A


Record No:240


ACCESS NO102056
GENEIL1R2
DESCRIPTIONInterleukin 1 receptor type II
NCBI ENTREZ ACCESS NO7850
UNIPROT ACCESS NOP27930
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis and asthma
SAMPLENasal epithelial cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput
COMMENTSHighly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table).
GEO_PRIDE_ACCESS_NOGSE44037
REFERENCE24282527
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL1 Receptor II for Human


Record No:241


ACCESS NO102057
GENEIRX4
DESCRIPTIONIroquois homeobox 4
NCBI ENTREZ ACCESS NO50805
UNIPROT ACCESS NOP78413
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis and asthma
SAMPLENasal epithelial cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput
COMMENTSHighly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table).
GEO_PRIDE_ACCESS_NOGSE44037
REFERENCE24282527
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:242


ACCESS NO102064
GENEIL4(Il-4)
DESCRIPTIONInterleukin 4
NCBI ENTREZ ACCESS NO3565
UNIPROT ACCESS NOP05112
ORGANISMHuman
DISEASE PHENOTYPEIntermittent allergic rhinitis
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSIncreased in monozygotic twins suffering from allergic rhinitis.
GEO_PRIDE_ACCESS_NOGSE37146
REFERENCE22515200
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL4 for Mouse


Record No:243


ACCESS NO102065
GENEIL5(IL-5)
DESCRIPTIONInterleukin 5
NCBI ENTREZ ACCESS NO3567
UNIPROT ACCESS NOP05113
ORGANISMHuman
DISEASE PHENOTYPEIntermittent allergic rhinitis
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSIncreased in monozygotic twins suffering from allergic rhinitis.
GEO_PRIDE_ACCESS_NOGSE37146
REFERENCE22515200
DRUG TARGETBE0001208
MONCLONAL ANTIBODYAnti-IL5 for Mouse/Human


Record No:244


ACCESS NO102066
GENEIL13(IL-13)
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO3596
UNIPROT ACCESS NOP35225
ORGANISMHuman
DISEASE PHENOTYPEIntermittent allergic rhinitis
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSIncreased in monozygotic twins suffering from allergic rhinitis.
GEO_PRIDE_ACCESS_NOGSE37146
REFERENCE22515200
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Mouse/Rat/Human


Record No:245


ACCESS NO102067
GENEIL17RB
DESCRIPTIONInterleukin 15 receptor B
NCBI ENTREZ ACCESS NO55540
UNIPROT ACCESS NOQ9NRM6
ORGANISMHuman
DISEASE PHENOTYPEIntermittent allergic rhinitis
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESMicroarray and RT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIncreased in monozygotic twins suffering from allergic rhinitis.
GEO_PRIDE_ACCESS_NOGSE37146
REFERENCE22515200
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL17B Receptor for Mouse


Record No:246


ACCESS NO102068
GENEIL4R
DESCRIPTIONInterleukin 4 receptor
NCBI ENTREZ ACCESS NO3566
UNIPROT ACCESS NOP24394
ORGANISMHuman
DISEASE PHENOTYPEIntermittent allergic rhinitis
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESMicroarray and RT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIncreased in monozygotic twins suffering from allergic rhinitis.
GEO_PRIDE_ACCESS_NOGSE37146
REFERENCE22515200
DRUG TARGETBE0002420
MONCLONAL ANTIBODYAnti-IL4R for Human


Record No:247


ACCESS NO102076
GENEIL-1F6
DESCRIPTIONIL-1 family member 6
NCBI ENTREZ ACCESS NO27179
UNIPROT ACCESS NOQ9UHA7
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDifferentially expressed in asthma. Involved in inflammation and immunoregulation.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:248


ACCESS NO102104
GENEIL-2R
DESCRIPTIONIL-2 receptor
NCBI ENTREZ ACCESS NO3559
UNIPROT ACCESS NOP01589
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in asthma. Involved in TH2 differentiation and Treg homeostasis.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGETBE0000658
MONCLONAL ANTIBODYN/A


Record No:249


ACCESS NO102110
GENEID2
DESCRIPTIONInhibitor of DNA binding 2
NCBI ENTREZ ACCESS NO3398
UNIPROT ACCESS NOQ02363
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in asthma. Involved in Th2/IgE regulation.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYAnti-ID2 for Human


Record No:250


ACCESS NO102111
GENEIL-13
DESCRIPTIONInterleukin 13
NCBI ENTREZ ACCESS NO3596
UNIPROT ACCESS NOP35225
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSUpregulated in asthma. Involved in Th2 regulation and function.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGETBE0002438
MONCLONAL ANTIBODYAnti-IL13 for Human


Record No:251


ACCESS NO102112
GENEIL-17RB
DESCRIPTIONInterleukin 17 receptor B
NCBI ENTREZ ACCESS NO55540
UNIPROT ACCESS NOQ9NRM6
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in asthma. Promotes Th2 memory expansion and function.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYAnti-IL17B Receptor for Human


Record No:252


ACCESS NO102113
GENEIL-4R
DESCRIPTIONInterleukin 4 receptor
NCBI ENTREZ ACCESS NO3566
UNIPROT ACCESS NOP24394
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSUpregulated in asthma. Involved in Th2 differentiation and Th2 memory stabilization.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGETBE0002420
MONCLONAL ANTIBODYAnti-IL4R for Human


Record No:253


ACCESS NO102114
GENEIL-5
DESCRIPTIONInterleukin 5
NCBI ENTREZ ACCESS NO3567
UNIPROT ACCESS NOP05113
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSUpregulated in asthma. Involved in Th2 regulation and function.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGETBE0001208
MONCLONAL ANTIBODYAnti-IL5 for Human


Record No:254


ACCESS NO102118
GENEIKZF4
DESCRIPTIONIKAROS family zinc finger 4
NCBI ENTREZ ACCESS NO64375
UNIPROT ACCESS NOQ9H2S9
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSUpregulated in atopic asthma. Involved in Treg expression and function.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYAnti-ZNFN1A4 for Mouse/Rat/Human


Record No:255


ACCESS NO102119
GENEITK
DESCRIPTIONIL2-inducible T cell kinase
NCBI ENTREZ ACCESS NO3702
UNIPROT ACCESS NOQ08881
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in atopic asthma.Involved in Th2 differentiation and activation.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGETBE0001341
MONCLONAL ANTIBODYAnti-ITK for Human


Record No:256


ACCESS NO102123
GENEIKZF1
DESCRIPTIONIKAROS family zinc finger 1
NCBI ENTREZ ACCESS NO10320
UNIPROT ACCESS NOQ13422
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDifferentialy expressed in asthma. Involved in transcriptional regulation.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYAnti-Ikaros for Human


Record No:257


ACCESS NO102134
GENEIMMT
DESCRIPTIONInner membrane protein mitochondrial
NCBI ENTREZ ACCESS NO10989
UNIPROT ACCESS NOQ16891
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSDifferentialy expressed in asthma. A lipd raft protein.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:258


ACCESS NO102143
GENEIGHG1
DESCRIPTIONImmunoglobulin heavy constant gamma 1
NCBI ENTREZ ACCESS NO3500
UNIPROT ACCESS NOP01857
ORGANISMHuman
DISEASE PHENOTYPEAllergic asthma
SAMPLEBronchial Biopsy
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDownregulated in allergic asthma.
GEO_PRIDE_ACCESS_NOGSE41649
REFERENCE19842841
DRUG TARGETBE0002815
MONCLONAL ANTIBODYAnti-Human IgG for Human


Record No:259


ACCESS NO102144
GENEIGKC
DESCRIPTIONImmunoglobulin kappa constant
NCBI ENTREZ ACCESS NO3514
UNIPROT ACCESS NOP01834
ORGANISMHuman
DISEASE PHENOTYPEAllergic asthma
SAMPLEBronchial Biopsy
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDownregulated in allergic asthma.
GEO_PRIDE_ACCESS_NOGSE41649
REFERENCE19842841
DRUG TARGETBE0003836
MONCLONAL ANTIBODYAnti-Kappa light chain for Human