BROWSE RESULT OF I
| 259 Records |
| ACCESS NO | 100034 |
| GENE | INPP4B |
| DESCRIPTION | Inositol polyphosphate-4-phosphatase type II |
| NCBI ENTREZ ACCESS NO | 8821 |
| UNIPROT ACCESS NO | O15327 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in high SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-INPP4B for Mouse/Rat/Human |
Record No:2
| ACCESS NO | 100073 |
| GENE | IL1RAP |
| DESCRIPTION | Interleukin 1 receptor accessory protein |
| NCBI ENTREZ ACCESS NO | 3556 |
| UNIPROT ACCESS NO | Q9NPH3 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in innate immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | BE0000565 |
| MONCLONAL ANTIBODY | Anti-IL1RAPL1 for Mouse/Human |
Record No:3
| ACCESS NO | 100086 |
| GENE | IL13RA1 |
| DESCRIPTION | Interleukin 13 receptor alpha 1 |
| NCBI ENTREZ ACCESS NO | 3597 |
| UNIPROT ACCESS NO | P78552 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL13 receptor alpha 1 for Human |
Record No:4
| ACCESS NO | 100087 |
| GENE | IL10 (IL-10) |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 3586 |
| UNIPROT ACCESS NO | P22301 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | Anti-IL10 for Mouse |
Record No:5
| ACCESS NO | 100088 |
| GENE | IL18 |
| DESCRIPTION | Interleukin 18 |
| NCBI ENTREZ ACCESS NO | 3606 |
| UNIPROT ACCESS NO | Q14116 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL18 for Pig |
Record No:6
| ACCESS NO | 100090 |
| GENE | IDO1 (INDO) |
| DESCRIPTION | Indoleamine dioxygenase 1 |
| NCBI ENTREZ ACCESS NO | 3620 |
| UNIPROT ACCESS NO | P14902 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | BE0000693 |
| MONCLONAL ANTIBODY | Anti-Indoleamine 2-3-dioxygenase for Human |
Record No:7
| ACCESS NO | 100097 |
| GENE | Itlnb |
| DESCRIPTION | Intelectin b |
| NCBI ENTREZ ACCESS NO | 493583 |
| UNIPROT ACCESS NO | O88310 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene is an epithelial product and significantly upregulated in allergic asthma. It is induced upon allergen challenge and as well as combinatorial effect of IL-4 plus IL-13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:8
| ACCESS NO | 100109 |
| GENE | Itgax |
| DESCRIPTION | Integrin a X |
| NCBI ENTREZ ACCESS NO | 16411 |
| UNIPROT ACCESS NO | Q9QXH4 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an IL-4 specific immunomodulatory gene in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:9
| ACCESS NO | 100119 |
| GENE | Ifi204 (Ifi16) |
| DESCRIPTION | IFN-gamma–inducible protein 16 |
| NCBI ENTREZ ACCESS NO | 15951 |
| UNIPROT ACCESS NO | P15092 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This host immune response gene is specifically induced by Th2 cytokines such as IL-4 and IL-13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IFI16 for Human |
Record No:10
| ACCESS NO | 100120 |
| GENE | Ifi47 |
| DESCRIPTION | IFN-gamma–inducible protein 47 |
| NCBI ENTREZ ACCESS NO | 15953 |
| UNIPROT ACCESS NO | Q61635 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This host immune response gene is specifically induced by Th2 cytokines such as IL-4 and IL-13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:11
| ACCESS NO | 100129 |
| GENE | Igtp |
| DESCRIPTION | Interferon gamma induced GTPase |
| NCBI ENTREZ ACCESS NO | 16145 |
| UNIPROT ACCESS NO | Q9DCE9 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an IL-4 specific host immune responsive gene induced in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:12
| ACCESS NO | 100130 |
| GENE | Iigp1 |
| DESCRIPTION | Interferon-inducible GTPase 1 |
| NCBI ENTREZ ACCESS NO | 60440 |
| UNIPROT ACCESS NO | Q9QZ85 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an IL-4 specific host immune responsive gene induced in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:13
| ACCESS NO | 100144 |
| GENE | IL1A |
| DESCRIPTION | Interleukin - 1 |
| NCBI ENTREZ ACCESS NO | 3552 |
| UNIPROT ACCESS NO | P01583 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL1 alpha for Human |
Record No:14
| ACCESS NO | 100148 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:15
| ACCESS NO | 100150 |
| GENE | IL11 |
| DESCRIPTION | Interleukin 11 |
| NCBI ENTREZ ACCESS NO | 3589 |
| UNIPROT ACCESS NO | P20809 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | BE0000416 |
| MONCLONAL ANTIBODY | N/A |
Record No:16
| ACCESS NO | 100156 |
| GENE | IL1RL1 |
| DESCRIPTION | Interleukin 1 receptor-like 1 |
| NCBI ENTREZ ACCESS NO | 9173 |
| UNIPROT ACCESS NO | Q01638 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:17
| ACCESS NO | 100163 |
| GENE | IRAK2 |
| DESCRIPTION | Interleukin-1 receptor-associated kinase 2 |
| NCBI ENTREZ ACCESS NO | 3656 |
| UNIPROT ACCESS NO | O43187 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | BE0000565 |
| MONCLONAL ANTIBODY | Anti-IRAK2 for Mouse/Rat/Human |
Record No:18
| ACCESS NO | 100169 |
| GENE | ITGB8 |
| DESCRIPTION | Integrin beta 8 |
| NCBI ENTREZ ACCESS NO | 3696 |
| UNIPROT ACCESS NO | P26012 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Integrin beta 8 for Human |
Record No:19
| ACCESS NO | 100171 |
| GENE | IL1B |
| DESCRIPTION | Interleukin 1 beta |
| NCBI ENTREZ ACCESS NO | 3553 |
| UNIPROT ACCESS NO | P01584 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | BE0001051 |
| MONCLONAL ANTIBODY | Anti-IL1B for Human |
Record No:20
| ACCESS NO | 100186 |
| GENE | IL13RA2 |
| DESCRIPTION | Interleukin 13 receptor alpha 2 |
| NCBI ENTREZ ACCESS NO | 3598 |
| UNIPROT ACCESS NO | Q14627 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This is a receptor protein significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | BE0002421 |
| MONCLONAL ANTIBODY | Anti-IL13 receptor alpha 2 for Human |
Record No:21
| ACCESS NO | 100226 |
| GENE | IER3 |
| DESCRIPTION | Immediate early response 3 |
| NCBI ENTREZ ACCESS NO | 8870 |
| UNIPROT ACCESS NO | P46695 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:22
| ACCESS NO | 100230 |
| GENE | IGFL1 |
| DESCRIPTION | Insulin growth factor-like family member 1 |
| NCBI ENTREZ ACCESS NO | 374918 |
| UNIPROT ACCESS NO | Q6UW32 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:23
| ACCESS NO | 100245 |
| GENE | IL8 |
| DESCRIPTION | Interleukin 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray and qRT-PCR followe |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is one of the major chemokine mediators of the inflammatory response. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:24
| ACCESS NO | 100247 |
| GENE | IL1R2 |
| DESCRIPTION | Interleukin 1 receptor type II |
| NCBI ENTREZ ACCESS NO | 7850 |
| UNIPROT ACCESS NO | P27930 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It acts as a decoy receptor that inhibits the activity of interleukin ligands. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL1 Receptor II for Human |
Record No:25
| ACCESS NO | 100253 |
| GENE | IL13RA2 |
| DESCRIPTION | Interleukin 13 receptor-alpha 2 |
| NCBI ENTREZ ACCESS NO | 3598 |
| UNIPROT ACCESS NO | Q14627 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This cytokine receptor is upregulated in rhinovirus induced allergic asthma. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | BE0002421 |
| MONCLONAL ANTIBODY | Anti-IL13 receptor alpha 2 for Human |
Record No:26
| ACCESS NO | 100257 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray and qRT-PCR followe |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This cytokine gene is more upregulated after rhinovirus infection as compared to normal asthma. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:27
| ACCESS NO | 100261 |
| GENE | IVNS1ABP |
| DESCRIPTION | Influenza virus NS1A binding protein |
| NCBI ENTREZ ACCESS NO | 10625 |
| UNIPROT ACCESS NO | Q9Y6Y0 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is a rhinoviral infection responsive protein down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:28
| ACCESS NO | 100269 |
| GENE | IFI44 |
| DESCRIPTION | Interferon-induced protein 44 |
| NCBI ENTREZ ACCESS NO | 10561 |
| UNIPROT ACCESS NO | Q8TCB0 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is a virus responsive protein and also participates in cell-cycle arrest. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:29
| ACCESS NO | 100270 |
| GENE | IL1B |
| DESCRIPTION | Interleukin 1 beta |
| NCBI ENTREZ ACCESS NO | 3553 |
| UNIPROT ACCESS NO | P01584 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray and qRT-PCR followe |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This is a proinflammatory cytokine found in the cell culture supernatent after rhinovirus infection. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | BE0001051 |
| MONCLONAL ANTIBODY | Anti-IL1B for Human |
Record No:30
| ACCESS NO | 100272 |
| GENE | INHBA |
| DESCRIPTION | Inhibin-beta A |
| NCBI ENTREZ ACCESS NO | 3624 |
| UNIPROT ACCESS NO | P08476 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows upregulation in uninfected asthma group. It is involved in airway repair and remodelling. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Inhibin beta A for Mouse/Rat/Human |
Record No:31
| ACCESS NO | 100284 |
| GENE | IGF2BP2 |
| DESCRIPTION | Insulin-like growth factor 2 mRNA binding protein 2 |
| NCBI ENTREZ ACCESS NO | 10644 |
| UNIPROT ACCESS NO | Q9Y6M1 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is upregulated in asthma exacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IGF2BP2 for Mouse/Rat/Human |
Record No:32
| ACCESS NO | 100286 |
| GENE | Icam1 |
| DESCRIPTION | Intercellular adhesion molecule 1 |
| NCBI ENTREZ ACCESS NO | 15894 |
| UNIPROT ACCESS NO | P13597 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Results of this study showed a decrease level in its transcription. This may be due to the fact that the monocytes do not encounter the particulate fungal conidia until reaching the lung. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | BE0001085 |
| MONCLONAL ANTIBODY | N/A |
Record No:33
| ACCESS NO | 100288 |
| GENE | Itgb4 |
| DESCRIPTION | integrin beta-4 |
| NCBI ENTREZ ACCESS NO | 192897 |
| UNIPROT ACCESS NO | A2A863 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in the movement of immune cells required for cell mediated immune response. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | BE0003298 |
| MONCLONAL ANTIBODY | Anti-Integrin beta 4 [M126] for Mouse/Rat/Human |
Record No:34
| ACCESS NO | 100301 |
| GENE | Il18bp |
| DESCRIPTION | Interleukin-18 binding protein |
| NCBI ENTREZ ACCESS NO | 16068 |
| UNIPROT ACCESS NO | Q9Z0M9 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in Cytokine signaling. It has been observed to be down regulated in the present study. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL18 binding protein for Rat/Human |
Record No:35
| ACCESS NO | 100305 |
| GENE | Il1rapl2 |
| DESCRIPTION | Interleukin-1 receptor accessory protein-like 2 |
| NCBI ENTREZ ACCESS NO | 60367 |
| UNIPROT ACCESS NO | Q9ERS6 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cytokine receptor. It has been observed to be up regulated in the present study. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL1RAPL2 for Human |
Record No:36
| ACCESS NO | 100369 |
| GENE | Inmt |
| DESCRIPTION | Thioether S-methyltransferase |
| NCBI ENTREZ ACCESS NO | 21743 |
| UNIPROT ACCESS NO | P40936 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergen induced asthma and Dexamethasone treatment |
| SAMPLE | Broncho Alveolar Lavage (BAL) |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This gene contributes to Selenium metabolism. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15378748 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Inmt for Human/Rat?mouse |
Record No:37
| ACCESS NO | 100404 |
| GENE | ICAM1 |
| DESCRIPTION | Intercellular adhesion molecule 1 (ICAM-1) |
| NCBI ENTREZ ACCESS NO | 102138837 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Monkey |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA microarrays and Quantitative RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in tissue remodeling. It is not or minimally regulated by IL4. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 12049661 |
| DRUG TARGET | BE0001085 |
| MONCLONAL ANTIBODY | Anti-ICAM1 for Rat/Human |
Record No:38
| ACCESS NO | 100513 |
| GENE | Inmt |
| DESCRIPTION | Indolethylamine N-methyltransferase |
| NCBI ENTREZ ACCESS NO | 21743 |
| UNIPROT ACCESS NO | P40936 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung eosinophil |
| TECHNIQUES | Compugen mouse 22K oligonucleotide microarrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in asthma susceptible strains. |
| GEO_PRIDE_ACCESS_NO | GSE15345 |
| REFERENCE | 19395375 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-INMT for Human/Rabbit/Mouse |
Record No:39
| ACCESS NO | 100517 |
| GENE | Il10 |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 16153 |
| UNIPROT ACCESS NO | P18893 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and role of Galectin-4 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Microarray-affymetrix + Real time RT PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is an intermediary cytokine involved in SOCS3 expression. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21547260 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | Anti-IL10 for Human/Rat/Mouse |
Record No:40
| ACCESS NO | 100519 |
| GENE | INHA |
| DESCRIPTION | inhibin alpha |
| NCBI ENTREZ ACCESS NO | 3623 |
| UNIPROT ACCESS NO | P05111 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cell |
| TECHNIQUES | RT PCR and microarray-affymetrix |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in CD4+ T cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | BE0000332 |
| MONCLONAL ANTIBODY | Anti-Inhibin alpha for Human/Rat/Mouse |
Record No:41
| ACCESS NO | 100520 |
| GENE | INHBA |
| DESCRIPTION | Activin A |
| NCBI ENTREZ ACCESS NO | 3624 |
| UNIPROT ACCESS NO | P08476 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cell |
| TECHNIQUES | RT PCR and microarray-affymetrix |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in CD4+ T cells. Currently it has been identified as Th2 cytokine. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-inhibin beta A for Human/Rat/Mouse |
Record No:42
| ACCESS NO | 100521 |
| GENE | IL9 |
| DESCRIPTION | Interleukin 9 |
| NCBI ENTREZ ACCESS NO | 3578 |
| UNIPROT ACCESS NO | P15248 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cell |
| TECHNIQUES | RT PCR and microarray-affymetrix |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | TH2 cell-derived cytokine involved in the development of the asthmatic phenotype. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL9 for Human |
Record No:43
| ACCESS NO | 100522 |
| GENE | IL13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cell |
| TECHNIQUES | RT PCR and microarray-affymetrix |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | TH2 cell-derived cytokine involved in the development of the asthmatic phenotype. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:44
| ACCESS NO | 100523 |
| GENE | IL10 |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 3586 |
| UNIPROT ACCESS NO | P22301 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cell |
| TECHNIQUES | RT PCR and microarray-affymetrix |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Overexpressed in atopic individuals. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | Anti-IL10 for Human/Rat/Mouse |
Record No:45
| ACCESS NO | 100532 |
| GENE | Ighg1(IgH-4) |
| DESCRIPTION | Immunoglobulin heavy constant gamma 1 |
| NCBI ENTREZ ACCESS NO | 16017 |
| UNIPROT ACCESS NO | P01868 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Tissue from left lung |
| TECHNIQUES | Affymetrix gene chip cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Asthma biomarker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18087161 |
| DRUG TARGET | BE0002815 |
| MONCLONAL ANTIBODY | Anti-Human IgG [EPR4421] for human |
Record No:46
| ACCESS NO | 100549 |
| GENE | Il2rb |
| DESCRIPTION | Interleukin 2 receptor-beta |
| NCBI ENTREZ ACCESS NO | 16185 |
| UNIPROT ACCESS NO | P16297 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Tissue from bronchial biopsy |
| TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is an immune signalling molecule. (data collected from supplementary table). |
| GEO_PRIDE_ACCESS_NO | GSE15823 |
| REFERENCE | 15038835 |
| DRUG TARGET | BE0000651 |
| MONCLONAL ANTIBODY | Anti-IL2 receptor beta (Allophycocyanin and FITC) for Mouse |
Record No:47
| ACCESS NO | 100554 |
| GENE | Igkc |
| DESCRIPTION | Immunoglobulin kappa constant |
| NCBI ENTREZ ACCESS NO | 16071 |
| UNIPROT ACCESS NO | P01837 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Tissue from bronchial biopsy |
| TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | downregulated in allergic asthma (data collected from supplementary table) |
| GEO_PRIDE_ACCESS_NO | GSE15823 |
| REFERENCE | 15038835 |
| DRUG TARGET | BE0003836 |
| MONCLONAL ANTIBODY | Anti-Kappa light chain for Human |
Record No:48
| ACCESS NO | 100555 |
| GENE | Iglj3 |
| DESCRIPTION | Immunoglobulin lambda joining 3 |
| NCBI ENTREZ ACCESS NO | 404740 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Tissue from bronchial biopsy |
| TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | downregulated in allergic asthma (data collected from supplementary table) |
| GEO_PRIDE_ACCESS_NO | GSE15823 |
| REFERENCE | 15038835 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:49
| ACCESS NO | 100593 |
| GENE | ITIH1 |
| DESCRIPTION | Inter-alpha-trypsin inhibitor heavy chain H1 |
| NCBI ENTREZ ACCESS NO | 3697 |
| UNIPROT ACCESS NO | P19827 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:50
| ACCESS NO | 100604 |
| GENE | IGHM |
| DESCRIPTION | immunoglobulin heavy constant mu |
| NCBI ENTREZ ACCESS NO | 3507 |
| UNIPROT ACCESS NO | P01871 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in immune response(present in supplimentary table) |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:51
| ACCESS NO | 100609 |
| GENE | IFNG |
| DESCRIPTION | interferon-gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | T cells from peripheral blood |
| TECHNIQUES | bisulphite-specific polymerase chain reaction (PCR |
| OMICS | Epigenetics |
| STUDY | Low Throughput |
| COMMENTS | Exposure to smoke and ambient air pollution leads to hypermethylation and thereby decreased expression of IFN gamma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23009259 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | Anti-IFNGR1 for Human |
Record No:52
| ACCESS NO | 100615 |
| GENE | Il4 |
| DESCRIPTION | interleukin 4 |
| NCBI ENTREZ ACCESS NO | 16189 |
| UNIPROT ACCESS NO | P07750 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Airway Inflammation |
| SAMPLE | CD4+ T cell |
| TECHNIQUES | Chip assay |
| OMICS | Epigenetics |
| STUDY | Low Throughput |
| COMMENTS | HDAC1 directly controls the gene locus of IL4 and loss of HDAC1 leads to increased IL4. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20702731 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Human/Mouse/Monkey |
Record No:53
| ACCESS NO | 100617 |
| GENE | Il13 |
| DESCRIPTION | interleukin 13 |
| NCBI ENTREZ ACCESS NO | 16163 |
| UNIPROT ACCESS NO | P20109 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | CD4+ T cell |
| TECHNIQUES | Nucleofection with Let-7 miRNA |
| OMICS | Epigenetics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | IL-13 is regulated by mmu-let-71. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20630862 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:54
| ACCESS NO | 100619 |
| GENE | IL2 |
| DESCRIPTION | Interleukin2 |
| NCBI ENTREZ ACCESS NO | 3558 |
| UNIPROT ACCESS NO | P60568 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Cord blood |
| TECHNIQUES | Pyrosequencing |
| OMICS | Epigenetics |
| STUDY | Low Throughput |
| COMMENTS | Increasing methylation in cord blood of a functional CpG site in the IL-2 promoter is associated with increased likelihood of severe asthma exacerbations. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23414538 |
| DRUG TARGET | BE0001029 |
| MONCLONAL ANTIBODY | Anti-IL2 for Human |
Record No:55
| ACCESS NO | 100639 |
| GENE | ITIH2 |
| DESCRIPTION | Inter-alpha (globulin) inhibitor H2 |
| NCBI ENTREZ ACCESS NO | 3698 |
| UNIPROT ACCESS NO | P19823 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
| SAMPLE | Nasal fluid |
| TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Enriched in acute phase response pathway. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21887273 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:56
| ACCESS NO | 100651 |
| GENE | ITIH4 |
| DESCRIPTION | ITI heavy chain H4 |
| NCBI ENTREZ ACCESS NO | 3700 |
| UNIPROT ACCESS NO | Q14624 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma proteins |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in coagulation cascade. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21471098 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-ITIH4 for Human |
Record No:57
| ACCESS NO | 100660 |
| GENE | IGHA1 |
| DESCRIPTION | IgA |
| NCBI ENTREZ ACCESS NO | 3493 |
| UNIPROT ACCESS NO | P01876 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma proteins |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in asthma compared to control. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21471098 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Human IgA for Human |
Record No:58
| ACCESS NO | 100661 |
| GENE | IGHM |
| DESCRIPTION | IgM heavy chain |
| NCBI ENTREZ ACCESS NO | 3507 |
| UNIPROT ACCESS NO | P01871 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma proteins |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in asthma compared to control. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21471098 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Human IgM for Human |
Record No:59
| ACCESS NO | 100674 |
| GENE | Inmt |
| DESCRIPTION | Indolethylamine N-methyltransferase |
| NCBI ENTREZ ACCESS NO | 21743 |
| UNIPROT ACCESS NO | P40936 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in chronic asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:60
| ACCESS NO | 100706 |
| GENE | ICAM-1 |
| DESCRIPTION | intercellular adhesion molecule 1 |
| NCBI ENTREZ ACCESS NO | 15894 |
| UNIPROT ACCESS NO | P13597 |
| ORGANISM | TSLP TG mice and BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid Broncho Alveol |
| TECHNIQUES | LC-MS/MS and Western blot and qRT PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Significantly increased in protein but not in mRNA level and involved in adhesion of leukocytes that are chemotaxing. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22837640 |
| DRUG TARGET | BE0001085 |
| MONCLONAL ANTIBODY | Anti-ICAM1 for Mouse/Human/Rat |
Record No:61
| ACCESS NO | 100725 |
| GENE | IGHA1 |
| DESCRIPTION | IGHA1 protein |
| NCBI ENTREZ ACCESS NO | 3493 |
| UNIPROT ACCESS NO | |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Blood plasma |
| TECHNIQUES | MALDI TOF MS and LC-MS/MS and Western Blot |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in atopic dermatitis patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19116453 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Human IgA for Human |
Record No:62
| ACCESS NO | 100749 |
| GENE | Ifng |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 15978 |
| UNIPROT ACCESS NO | P01580 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in monocytes from allergic animals.Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | Anti-Interferon gamma for Mouse/Human |
Record No:63
| ACCESS NO | 100750 |
| GENE | IL1r2 |
| DESCRIPTION | Interleukin-1 receptor |
| NCBI ENTREZ ACCESS NO | 16178 |
| UNIPROT ACCESS NO | P27931 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in monocytes from allergic animals.Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL1 Receptor II for Human |
Record No:64
| ACCESS NO | 100751 |
| GENE | Itga4 |
| DESCRIPTION | Integrin alpha-4 |
| NCBI ENTREZ ACCESS NO | 16401 |
| UNIPROT ACCESS NO | Q00651 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in cellular adhesion. Downregulated after fungal allergen induction.Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | BE0000590 |
| MONCLONAL ANTIBODY | Anti-Integrin alpha 4 for Rat/Human |
Record No:65
| ACCESS NO | 100755 |
| GENE | Igfbp1 |
| DESCRIPTION | Insulin-like growth factor binding protein 1 |
| NCBI ENTREZ ACCESS NO | 16006 |
| UNIPROT ACCESS NO | P47876 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IGFBP1 for Mouse/Rat/Human |
Record No:66
| ACCESS NO | 100774 |
| GENE | IL10 |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 3586 |
| UNIPROT ACCESS NO | P22301 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | DNA |
| TECHNIQUES | Illumina Human Hap 550Kv3 BeadChip SNP array |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Inhibits synthesis of IFN gamma and IL2. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19264973 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | Anti-IL10 for Mouse/Rat/Human |
Record No:67
| ACCESS NO | 100779 |
| GENE | INPP4A |
| DESCRIPTION | Inositol polyphosphate-4-phosphatase |
| NCBI ENTREZ ACCESS NO | 3631 |
| UNIPROT ACCESS NO | Q96PE3 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | DNA |
| TECHNIQUES | Illumina Human Hap 550Kv3 BeadChip SNP array |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | rs11676357 SNP is associated with asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19264973 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-INPP4A for Mouse/Rat/Human |
Record No:68
| ACCESS NO | 100784 |
| GENE | IRAK3 |
| DESCRIPTION | Interleukin-1 receptor-associated kinase 3 |
| NCBI ENTREZ ACCESS NO | 11213 |
| UNIPROT ACCESS NO | Q9Y616 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | DNA |
| TECHNIQUES | Illumina Human Hap 550Kv3 BeadChip SNP array |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Expressed mainly in the peripheral blood lymphocytes. Rs1152912 SNP is associated with asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19264973 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IRAKM for Human |
Record No:69
| ACCESS NO | 100787 |
| GENE | ITGB3 |
| DESCRIPTION | Integrin beta 3 |
| NCBI ENTREZ ACCESS NO | 3690 |
| UNIPROT ACCESS NO | P05106 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | DNA |
| TECHNIQUES | Illumina Human Hap 550Kv3 BeadChip SNP array |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Risk allele rs11869835 is associated with asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19264973 |
| DRUG TARGET | BE0001155 |
| MONCLONAL ANTIBODY | Anti-Integrin beta 3 for Mouse/Rat/Human |
Record No:70
| ACCESS NO | 100826 |
| GENE | Igf1 |
| DESCRIPTION | Insulin like growth fator 1 |
| NCBI ENTREZ ACCESS NO | 16000 |
| UNIPROT ACCESS NO | P05017 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | More expressed after short term allergen exposure in allergic BALB/c mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0003418 |
| MONCLONAL ANTIBODY | N/A |
Record No:71
| ACCESS NO | 100848 |
| GENE | IL5 |
| DESCRIPTION | Interleukin-5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Affymetrix oligonucleotide microarray and RTPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Terminal differentiation of B cells to immunoglobulin producing cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Mouse/Human |
Record No:72
| ACCESS NO | 100849 |
| GENE | IL4 |
| DESCRIPTION | Interleukin-4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Affymetrix oligonucleotide microarray and RTPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Enhances surface secretion and cell surface excretion of IgE. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Mouse/Human |
Record No:73
| ACCESS NO | 100850 |
| GENE | IL9 |
| DESCRIPTION | Interleukin-9 |
| NCBI ENTREZ ACCESS NO | 3578 |
| UNIPROT ACCESS NO | P15248 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Affymetrix oligonucleotide microarray and RTPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in subjects from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL9 for Mouse/Human |
Record No:74
| ACCESS NO | 100852 |
| GENE | INHA |
| DESCRIPTION | Inhibin alpha |
| NCBI ENTREZ ACCESS NO | 3623 |
| UNIPROT ACCESS NO | P05111 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Affymetrix oligonucleotide microarray and RTPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Increased in CD4+ T cells of asthmatic subjects. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Inhibin alpha for Mouse/Rat/Human |
Record No:75
| ACCESS NO | 100853 |
| GENE | IL13 |
| DESCRIPTION | Interleukin-13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Affymetrix oligonucleotide microarray and RTPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Overexpressed in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:76
| ACCESS NO | 100855 |
| GENE | IL10 |
| DESCRIPTION | Interleukin-10 |
| NCBI ENTREZ ACCESS NO | 3586 |
| UNIPROT ACCESS NO | P22301 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Affymetrix oligonucleotide microarray and RTPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Increased in patients suffering from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | Anti-IL10 for Human |
Record No:77
| ACCESS NO | 100856 |
| GENE | INHBA |
| DESCRIPTION | Activin AB alpha polypeptide |
| NCBI ENTREZ ACCESS NO | 3624 |
| UNIPROT ACCESS NO | P08476 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Affymetrix oligonucleotide microarray and RTPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Increased in patients suffering from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Inhibin beta A for Mouse/Rat/Human |
Record No:78
| ACCESS NO | 100859 |
| GENE | IL12RB2 |
| DESCRIPTION | Interleukin 12 receptor beta 2 |
| NCBI ENTREZ ACCESS NO | 3595 |
| UNIPROT ACCESS NO | Q99665 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Affymetrix oligonucleotide microarray and RTPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in patients suffering from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18269679 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:79
| ACCESS NO | 100903 |
| GENE | ITGB2 |
| DESCRIPTION | Integrin beta 2 |
| NCBI ENTREZ ACCESS NO | 3689 |
| UNIPROT ACCESS NO | P05107 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic sensitization to pollen allergens |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Illumina microarray chips and Genome wide associat |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Triggers neutrophil transmigration in case of lung injury. Downregulated in this study. |
| GEO_PRIDE_ACCESS_NO | GSE18577 |
| REFERENCE | 24116013 |
| DRUG TARGET | BE0001041 |
| MONCLONAL ANTIBODY | N/A |
Record No:80
| ACCESS NO | 100904 |
| GENE | ITGAX |
| DESCRIPTION | Integrin alpha X |
| NCBI ENTREZ ACCESS NO | 3687 |
| UNIPROT ACCESS NO | P20702 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic sensitization to pollen allergens |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Illumina microarray chips and Genome wide associat |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in the complement system pathway. Downregulated in allergic patients. |
| GEO_PRIDE_ACCESS_NO | GSE18578 |
| REFERENCE | 24116013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD11c for Mouse/Rat/Human |
Record No:81
| ACCESS NO | 100910 |
| GENE | ITGAL |
| DESCRIPTION | Integrin alpha L |
| NCBI ENTREZ ACCESS NO | 3683 |
| UNIPROT ACCESS NO | P20701 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic sensitization to pollen allergens |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Illumina microarray chips and Genome wide associat |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | |
| GEO_PRIDE_ACCESS_NO | GSE18584 |
| REFERENCE | 24116013 |
| DRUG TARGET | BE0000516 |
| MONCLONAL ANTIBODY | Anti-CD11a for Mouse/Human |
Record No:82
| ACCESS NO | 100911 |
| GENE | IL17RB |
| DESCRIPTION | Interleukin 17 receptor B |
| NCBI ENTREZ ACCESS NO | 55540 |
| UNIPROT ACCESS NO | Q9NRM6 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | PBMC |
| TECHNIQUES | Illumina Beadarray |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Significantly upregulated after pollen allergen exposure in seasonal allergic rhinitis patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21252617 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL17B Receptor for Mouse/Human |
Record No:83
| ACCESS NO | 100914 |
| GENE | Igh6 |
| DESCRIPTION | Immunoglobulin heavy chain complex |
| NCBI ENTREZ ACCESS NO | 16019 |
| UNIPROT ACCESS NO | |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in humoral immune response. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:84
| ACCESS NO | 100915 |
| GENE | Igj |
| DESCRIPTION | Immunoglobulin joining chain |
| NCBI ENTREZ ACCESS NO | 16069 |
| UNIPROT ACCESS NO | P01592 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Involved in humoral immune response. Downregulated in all three food allergen sensitization |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IGJ for Human |
Record No:85
| ACCESS NO | 100924 |
| GENE | Itgb1 |
| DESCRIPTION | Integrin beta 1 |
| NCBI ENTREZ ACCESS NO | 16412 |
| UNIPROT ACCESS NO | P09055 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated after beta lactoglobulin induction. Expressed on lymphocytes monocytes eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | BE0003575 |
| MONCLONAL ANTIBODY | Anti-Integrin beta 1 for Mouse/Rat/Human |
Record No:86
| ACCESS NO | 100949 |
| GENE | IL7 |
| DESCRIPTION | Interleukin 7 |
| NCBI ENTREZ ACCESS NO | 3574 |
| UNIPROT ACCESS NO | P13232 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Eosinophils from Peripheral blood |
| TECHNIQUES | Western blotting Flow cytometry ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Facilitates maturation survival of T cells and activation of eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19155487 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL7 for Human |
Record No:87
| ACCESS NO | 100957 |
| GENE | IP-10 |
| DESCRIPTION | Inhibitory protein 10 |
| NCBI ENTREZ ACCESS NO | 3627 |
| UNIPROT ACCESS NO | P02778 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in Obese patients |
| SAMPLE | Peripheral Blood mononuclear cells |
| TECHNIQUES | Flow cytometry and immunoflorescent staining |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Cause Inflammation and increased in obese patients compared to non-obese. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23760409 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IP10 for Mouse/Human |
Record No:88
| ACCESS NO | 100960 |
| GENE | ITGB3 |
| DESCRIPTION | Integrin beta 3 |
| NCBI ENTREZ ACCESS NO | 3690 |
| UNIPROT ACCESS NO | P05106 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | DNA from blood |
| TECHNIQUES | Genotyping |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Single nucleotide polymorphisms in this gene has been significantly associated with asthma in western populations |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23451109 |
| DRUG TARGET | BE0001155 |
| MONCLONAL ANTIBODY | Anti-Integrin beta 3 for Mouse/Rat/Human |
Record No:89
| ACCESS NO | 100976 |
| GENE | IFNG (IFN- gamma) |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 15978 |
| UNIPROT ACCESS NO | P01580 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic diseases and effect of dibutyl phthalate (DBP) |
| SAMPLE | Ear tissue |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein level is significantly elevated after exposure to DBP combined with FITC as compared to saline challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24498391 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | N/A |
Record No:90
| ACCESS NO | 100977 |
| GENE | Il4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 16189 |
| UNIPROT ACCESS NO | P07750 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic diseases and effect of dibutyl phthalate (DBP) |
| SAMPLE | Ear tissue |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein level is significantly elevated after exposure to DBP combined with FITC as compared to saline challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24498391 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:91
| ACCESS NO | 100978 |
| GENE | Il5 (IL-5) |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 16191 |
| UNIPROT ACCESS NO | P04401 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic diseases and effect of dibutyl phthalate (DBP) |
| SAMPLE | Ear tissue |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein level is significantly elevated after exposure to DBP combined with FITC as compared to saline challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24498391 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:92
| ACCESS NO | 100979 |
| GENE | Il13 (IL-13) |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 16163 |
| UNIPROT ACCESS NO | P20109 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic diseases and effect of dibutyl phthalate (DBP) |
| SAMPLE | Ear tissue |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein level is significantly elevated after exposure to DBP combined with FITC as compared to saline challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24498391 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:93
| ACCESS NO | 100980 |
| GENE | IL1A (IL-1A) |
| DESCRIPTION | Interleukin 1 alpha |
| NCBI ENTREZ ACCESS NO | 3552 |
| UNIPROT ACCESS NO | P01583 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Occupational asthma |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expression of this pro-inflammatory mediator is significantly increased after exposure to the respiratory sensitizers trimellitic anhydride (TMA) and ammonium hexa chloroplatinate (HClPt) at subtoxic concentrations. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL1 alpha for Human |
Record No:94
| ACCESS NO | 100982 |
| GENE | IL10 |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 3586 |
| UNIPROT ACCESS NO | P22301 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Occupational asthma |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | Meso Scale Discovery Assays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | IL-10 production was significantly increased (3.0-fold) after exposure to both respiratory allergens TMA and HClPt. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | BE00002484 |
| MONCLONAL ANTIBODY | Anti-IL10 for Human |
Record No:95
| ACCESS NO | 100983 |
| GENE | IFNG (IFN- gamma) |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Occupational asthma |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | Meso Scale Discovery Assays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This TH-1 cytokine IFN-Îł is significantly induced by HClPt with up to 2810%. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | N/A |
Record No:96
| ACCESS NO | 100984 |
| GENE | IL2 |
| DESCRIPTION | Interleukin 2 |
| NCBI ENTREZ ACCESS NO | 3558 |
| UNIPROT ACCESS NO | P60568 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Occupational asthma |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | Meso Scale Discovery Assays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokine is significantly induced by HClPt. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | BE0001029 |
| MONCLONAL ANTIBODY | Anti-IL2 antibody [AP-MAB0844] for Mouse |
Record No:97
| ACCESS NO | 100985 |
| GENE | IL13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Occupational asthma |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | Meso Scale Discovery Assays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This Th-2 cytokine is significantly induced by HClPt with up to 1320%. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:98
| ACCESS NO | 100986 |
| GENE | IL5 |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Occupational asthma |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | Meso Scale Discovery Assays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokine is significantly induced by HClPt with up to 620%. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:99
| ACCESS NO | 100990 |
| GENE | IL5 |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:100
| ACCESS NO | 100991 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:101
| ACCESS NO | 100995 |
| GENE | IL1B (IL-1B) |
| DESCRIPTION | Interleukin 1 beta |
| NCBI ENTREZ ACCESS NO | 3553 |
| UNIPROT ACCESS NO | P01584 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0001051 |
| MONCLONAL ANTIBODY | Anti-IL1B for Human |
Record No:102
| ACCESS NO | 101010 |
| GENE | IL1B |
| DESCRIPTION | IL-1 b |
| NCBI ENTREZ ACCESS NO | 3553 |
| UNIPROT ACCESS NO | P01584 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows highest expression in patients with neutrophilic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | BE0001051 |
| MONCLONAL ANTIBODY | Anti-IL1B for Human |
Record No:103
| ACCESS NO | 101011 |
| GENE | IL1R2 |
| DESCRIPTION | IL-1 receptor type II |
| NCBI ENTREZ ACCESS NO | 7850 |
| UNIPROT ACCESS NO | P27930 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows highest expression in patients with neutrophilic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL1 Receptor II for Human |
Record No:104
| ACCESS NO | 101012 |
| GENE | IL1RN |
| DESCRIPTION | IL-1 receptor antagonist |
| NCBI ENTREZ ACCESS NO | 3557 |
| UNIPROT ACCESS NO | P18510 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows highest expression in patients with neutrophilic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:105
| ACCESS NO | 101013 |
| GENE | IRAK2 |
| DESCRIPTION | IL-1 receptor associated kinase 2 |
| NCBI ENTREZ ACCESS NO | 3656 |
| UNIPROT ACCESS NO | O43187 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows highest expression in patients with neutrophilic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | BE0000565 |
| MONCLONAL ANTIBODY | Anti-IRAK2 for Mouse/Rat/Human |
Record No:106
| ACCESS NO | 101014 |
| GENE | ISG20 |
| DESCRIPTION | Interferon stimulated exonuclease gene 20kDa |
| NCBI ENTREZ ACCESS NO | 3669 |
| UNIPROT ACCESS NO | Q96AZ6 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows highest expression in patients with neutrophilic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | BE0001938 |
| MONCLONAL ANTIBODY | Anti-ISG20 for Human |
Record No:107
| ACCESS NO | 101044 |
| GENE | IVL |
| DESCRIPTION | Involucrin |
| NCBI ENTREZ ACCESS NO | 3713 |
| UNIPROT ACCESS NO | P07476 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly down regulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Involucrin for Human |
Record No:108
| ACCESS NO | 101055 |
| GENE | IL13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Treatment with an anti-IL13 monoclonal antibody Lebrikizumab significantly improves prebronchodilator forced expiratory volume in 1 s (FEV(1)) in a subset of subjects with uncontrolled asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24131304 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:109
| ACCESS NO | 101066 |
| GENE | IGHE (IgE) |
| DESCRIPTION | Immunoglobulin E |
| NCBI ENTREZ ACCESS NO | 3497 |
| UNIPROT ACCESS NO | P01854 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IgE [XTE4] for Human |
Record No:110
| ACCESS NO | 101068 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:111
| ACCESS NO | 101070 |
| GENE | IL17A (IL17) |
| DESCRIPTION | Interleukin 17A |
| NCBI ENTREZ ACCESS NO | 3605 |
| UNIPROT ACCESS NO | Q16552 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:112
| ACCESS NO | 101085 |
| GENE | Igha (IgA) |
| DESCRIPTION | Immunoglobulin alpha |
| NCBI ENTREZ ACCESS NO | 238447 |
| UNIPROT ACCESS NO | |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic disorder and prebiotics induced tolerance |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein is highly expressed after allergen sensitization in prebiotic-fed mice. It is related to tolerance and would play a crucial role in the prevention of allergy. Perinatal and postweaning exposure to prebiotics is very encouraging because it allows the induction of several tolerance-related biomarkers |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IgA a for Human |
Record No:113
| ACCESS NO | 101086 |
| GENE | Ighv1-9 (IgG2a) |
| DESCRIPTION | Immunoglobulin G2A |
| NCBI ENTREZ ACCESS NO | 668478 |
| UNIPROT ACCESS NO | |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic disorder and prebiotics induced tolerance |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein is highly expressed after allergen sensitization in prebiotic-fed mice. It is related to tolerance and would play a crucial role in the prevention of allergy. Perinatal and postweaning exposure to prebiotics is very encouraging because it allows the induction of several tolerance-related biomarkers |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:114
| ACCESS NO | 101087 |
| GENE | Il10 (IL-10) |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 16153 |
| UNIPROT ACCESS NO | P18893 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic disorder and prebiotics induced tolerance |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein is highly expressed after allergen sensitization in prebiotic-fed mice. It is related to tolerance and would play a crucial role in the prevention of allergy. Perinatal and postweaning exposure to prebiotics is very encouraging because it allows the induction of several tolerance-related biomarkers |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | N/A |
Record No:115
| ACCESS NO | 101089 |
| GENE | IFNG (IFN- gamma) |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 15978 |
| UNIPROT ACCESS NO | P01580 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic disorder and prebiotics induced tolerance |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein is highly expressed after allergen sensitization in prebiotic-fed mice. It is related to tolerance and would play a crucial role in the prevention of allergy. Perinatal and postweaning exposure to prebiotics is very encouraging because it allows the induction of several tolerance-related biomarkers |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | N/A |
Record No:116
| ACCESS NO | 101090 |
| GENE | Il4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 16189 |
| UNIPROT ACCESS NO | P07750 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic disorder and prebiotics induced tolerance |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is a biomarker related to allergy and is not affected anyway by allergen challenge followed by prebiotic injestion due to expression of tolerance related biomarkers. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:117
| ACCESS NO | 101091 |
| GENE | Il17a (IL-17a) |
| DESCRIPTION | Interleukin-17a |
| NCBI ENTREZ ACCESS NO | 16171 |
| UNIPROT ACCESS NO | Q62386 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic disorder and prebiotics induced tolerance |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is a biomarker related to allergy and is not affected anyway by allergen challenge followed by prebiotic injestion due to expression of tolerance related biomarkers. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:118
| ACCESS NO | 101093 |
| GENE | Ighe (IgE) |
| DESCRIPTION | Immunoglobulin E |
| NCBI ENTREZ ACCESS NO | 380792 |
| UNIPROT ACCESS NO | P06336 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic disorder and prebiotics induced tolerance |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is a biomarker related to allergy and is not affected anyway by allergen challenge followed by prebiotic injestion due to expression of tolerance related biomarkers. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IgE [XTE4] for Human |
Record No:119
| ACCESS NO | 101095 |
| GENE | ICAM1 (sICAM-1) |
| DESCRIPTION | Intercellular adhesion molecule 1 |
| NCBI ENTREZ ACCESS NO | 3383 |
| UNIPROT ACCESS NO | P0536 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Patients with shortness in breath can be treated effectively with fluticasone effectively. The effectiveness of treatment can be monitered by significant changes in this biomarker level in serum. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23606983 |
| DRUG TARGET | BE0001085 |
| MONCLONAL ANTIBODY | Anti-ICAM1 for Rat/Human |
Record No:120
| ACCESS NO | 101098 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an indicator of exacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23521049 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:121
| ACCESS NO | 101125 |
| GENE | IFNG (IFN- gamma) |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Pediatric asthma and Polycyclic aromatic hydrocarbon exposure |
| SAMPLE | Fasting blood |
| TECHNIQUES | Multiplex immunoassay using Luminex 100 system pla |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Exposure to polycyclic hydrocarbon has strong association with decrease in serum concentration of this biomarker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23286340 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | N/A |
Record No:122
| ACCESS NO | 101126 |
| GENE | IL5 |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Pediatric asthma and Polycyclic aromatic hydrocarbon exposure |
| SAMPLE | Fasting blood |
| TECHNIQUES | Multiplex immunoassay using Luminex 100 system pla |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Exposure to polycyclic hydrocarbon has strong association with decrease in serum concentration of this biomarker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23286340 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:123
| ACCESS NO | 101128 |
| GENE | IL10 |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 3586 |
| UNIPROT ACCESS NO | P22301 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Pediatric asthma and Polycyclic aromatic hydrocarbon exposure |
| SAMPLE | Fasting blood |
| TECHNIQUES | Multiplex immunoassay using Luminex 100 system pla |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Exposure to polycyclic hydrocarbon has strong association with decrease in serum concentration of this biomarker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23286340 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | Anti-IL10 for Human |
Record No:124
| ACCESS NO | 101129 |
| GENE | IL4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Pediatric asthma and Polycyclic aromatic hydrocarbon exposure |
| SAMPLE | Fasting blood |
| TECHNIQUES | Multiplex immunoassay using Luminex 100 system pla |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Exposure to polycyclic hydrocarbon has strong association with increase in serum concentration of this biomarker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23286340 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:125
| ACCESS NO | 101140 |
| GENE | IL4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of Di-(2-ethylhexyl) phthalate (DEHP) |
| SAMPLE | Extracts of lung tissue |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This inflammatory marker is upregulated upon DHAP exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22701742 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:126
| ACCESS NO | 101141 |
| GENE | IFNG (IFN-Îł) |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of Di-(2-ethylhexyl) phthalate (DEHP) |
| SAMPLE | Extracts of lung tissue |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This inflammatory marker is upregulated upon DHAP exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22701742 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | N/A |
Record No:127
| ACCESS NO | 101146 |
| GENE | IL1B (IL-1B) |
| DESCRIPTION | Interleukin 1 beta |
| NCBI ENTREZ ACCESS NO | 3553 |
| UNIPROT ACCESS NO | P01584 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Higher levels of this biomarker is associated with male sex. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0001051 |
| MONCLONAL ANTIBODY | Anti-IL1B for Human |
Record No:128
| ACCESS NO | 101147 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokoine is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:129
| ACCESS NO | 101148 |
| GENE | IL10 |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 3586 |
| UNIPROT ACCESS NO | P22301 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokoine is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | Anti-IL10Â for Mouse |
Record No:130
| ACCESS NO | 101150 |
| GENE | IL7 |
| DESCRIPTION | Interleukin 7 |
| NCBI ENTREZ ACCESS NO | 3574 |
| UNIPROT ACCESS NO | P13232 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokoine is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:131
| ACCESS NO | 101152 |
| GENE | IL17A (IL17) |
| DESCRIPTION | Interleukin 17A |
| NCBI ENTREZ ACCESS NO | 3605 |
| UNIPROT ACCESS NO | Q16552 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokoine is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:132
| ACCESS NO | 101153 |
| GENE | IL13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokoine is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:133
| ACCESS NO | 101164 |
| GENE | IRF4 |
| DESCRIPTION | Interferon regulatory factor 4 |
| NCBI ENTREZ ACCESS NO | 3662 |
| UNIPROT ACCESS NO | Q15306 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
| SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
| TECHNIQUES | 2D-DIGE and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene was overexpressed after LPS challenge and as well as grass pollen immunotherapy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22464673 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:134
| ACCESS NO | 101179 |
| GENE | Il4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 16189 |
| UNIPROT ACCESS NO | P07750 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effect of a bioactive flavonol Fisetin |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Fisetin dose-dependently inhibited ovalbumin-induced increases in this marker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22290391 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:135
| ACCESS NO | 101180 |
| GENE | Il5 (IL-5) |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 16191 |
| UNIPROT ACCESS NO | P04401 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effect of a bioactive flavonol Fisetin |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Fisetin dose-dependently inhibited ovalbumin-induced increases in this marker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22290391 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:136
| ACCESS NO | 101181 |
| GENE | Il13 (IL-13) |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 16163 |
| UNIPROT ACCESS NO | P20109 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effect of a bioactive flavonol Fisetin |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Fisetin dose-dependently inhibited ovalbumin-induced increases in this marker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22290391 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:137
| ACCESS NO | 101182 |
| GENE | Il17a (IL-17a) |
| DESCRIPTION | Interleukin-17a |
| NCBI ENTREZ ACCESS NO | 16171 |
| UNIPROT ACCESS NO | Q62386 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effect of a bioactive flavonol Fisetin |
| SAMPLE | Lung tissue |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Fisetin attenuated ovalbumin-induced expression of this gene. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22290391 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:138
| ACCESS NO | 101184 |
| GENE | Il33 |
| DESCRIPTION | Interleukin 33 |
| NCBI ENTREZ ACCESS NO | 77125 |
| UNIPROT ACCESS NO | Q8BVZ5 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effect of a bioactive flavonol Fisetin |
| SAMPLE | Lung tissue |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Fisetin attenuated ovalbumin-induced expression of this gene. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22290391 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL33 for Mouse/Human |
Record No:139
| ACCESS NO | 101191 |
| GENE | IL13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | TGF beta activation was also greater in children with severe asthma and was associated with higher IL-13 concentrations. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22206775 |
| DRUG TARGET | BE0000984 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:140
| ACCESS NO | 101208 |
| GENE | IKZF1 |
| DESCRIPTION | IKAROS zinc finger protein 1 |
| NCBI ENTREZ ACCESS NO | 10320 |
| UNIPROT ACCESS NO | Q13422 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Ikaros [SP108] for Human/Rat |
Record No:141
| ACCESS NO | 101209 |
| GENE | IL17F |
| DESCRIPTION | Interleukin-17F |
| NCBI ENTREZ ACCESS NO | 112744 |
| UNIPROT ACCESS NO | Q96PD4 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL17F [4H1629] for Human |
Record No:142
| ACCESS NO | 101226 |
| GENE | IKZF3 |
| DESCRIPTION | Zinc finger protein Aiolos |
| NCBI ENTREZ ACCESS NO | 22806 |
| UNIPROT ACCESS NO | Q9UKT9 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IKZF3 for Human |
Record No:143
| ACCESS NO | 101229 |
| GENE | IL1B (IL-1B) |
| DESCRIPTION | Interleukin 1 beta |
| NCBI ENTREZ ACCESS NO | 3553 |
| UNIPROT ACCESS NO | P01584 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Skin allergy induced by formaldehyde |
| SAMPLE | THP-1 cell line |
| TECHNIQUES | qPCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This inflammatory marker is upregulated upon bronopol challenge in a time depenent manner. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22034943 |
| DRUG TARGET | BE0001051 |
| MONCLONAL ANTIBODY | Anti-IL1B for Human |
Record No:144
| ACCESS NO | 101234 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma and obesity related asthma |
| SAMPLE | Fasting serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This is a Th1 specific biomarker can distinguish obesity asthma from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21980061 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:145
| ACCESS NO | 101235 |
| GENE | IFNG (IFN-Îł) |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma and obesity related asthma |
| SAMPLE | Fasting serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This is a Th1 specific biomarker can distinguish obesity asthma from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21980061 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | N/A |
Record No:146
| ACCESS NO | 101237 |
| GENE | IL4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma and obesity related asthma |
| SAMPLE | Fasting serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This is a Th2 specific biomarker can distinguish obesity asthma from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21980061 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:147
| ACCESS NO | 101238 |
| GENE | IL5 |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma and obesity related asthma |
| SAMPLE | Fasting serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This is a Th2 specific biomarker can distinguish obesity asthma from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21980061 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:148
| ACCESS NO | 101239 |
| GENE | IL13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma and obesity related asthma |
| SAMPLE | Fasting serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This is a Th2 specific biomarker can distinguish obesity asthma from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21980061 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:149
| ACCESS NO | 101242 |
| GENE | IGHE (IgE) |
| DESCRIPTION | Immunoglobulin E |
| NCBI ENTREZ ACCESS NO | 3497 |
| UNIPROT ACCESS NO | P01854 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy |
| SAMPLE | Serum |
| TECHNIQUES | Aptamer-based biosensor (apta-biosensor) using CNT |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | In this study the described aptamer-based CNT-FET device enable the production of label-free ultrasensitive electronic biosensors to detect IgE in allergic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21780424 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IgE [XTE4] for Human |
Record No:150
| ACCESS NO | 101244 |
| GENE | Il4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 16189 |
| UNIPROT ACCESS NO | P07750 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
| SAMPLE | Lymphocyte |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Artesunate significantly reduces the level of this Th2 specific inflammatory cytokine induced after ovalbumin challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:151
| ACCESS NO | 101245 |
| GENE | Il5 (IL-5) |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 16191 |
| UNIPROT ACCESS NO | P04401 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
| SAMPLE | Lymphocyte |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Artesunate significantly reduces the level of this Th2 specific inflammatory cytokine induced after ovalbumin challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:152
| ACCESS NO | 101246 |
| GENE | Il13 (IL-13) |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 16163 |
| UNIPROT ACCESS NO | P20109 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
| SAMPLE | Lymphocyte |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Artesunate significantly reduces the level of this Th2 specific inflammatory cytokine induced after ovalbumin challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:153
| ACCESS NO | 101250 |
| GENE | Il17a (IL-17a) |
| DESCRIPTION | Interleukin-17a |
| NCBI ENTREZ ACCESS NO | 16171 |
| UNIPROT ACCESS NO | Q62386 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
| SAMPLE | Lung tissue |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Pretreatment with artesunate (30 mg/kg) demonstrated strong suppression of this cytokine essential for airway inflammation and remodeling. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:154
| ACCESS NO | 101251 |
| GENE | Il33 |
| DESCRIPTION | Interleukin 33 |
| NCBI ENTREZ ACCESS NO | 77125 |
| UNIPROT ACCESS NO | Q8BVZ5 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
| SAMPLE | Lung tissue |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Pretreatment with artesunate (30 mg/kg) demonstrated strong suppression of this cytokine essential for airway inflammation and remodeling. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL33 for Mouse/Human |
Record No:155
| ACCESS NO | 101255 |
| GENE | Icam1 |
| DESCRIPTION | Intercellular adhesion molecule 1 |
| NCBI ENTREZ ACCESS NO | 15894 |
| UNIPROT ACCESS NO | P13597 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
| SAMPLE | Lung tissue |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Pretreatment with artesunate (30 mg/kg) demonstrated strong suppression of this gene that is pivotal for pulmonary recruitment of inflammatory cells like eosinophils and lymphoctyes. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | BE0001085 |
| MONCLONAL ANTIBODY | Anti-ICAM1 for Rat/Human |
Record No:156
| ACCESS NO | 101264 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe and mild asthma |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This study suggests that there is not any difference between severe and mild asthma in serum IL-8 and IL-6. Thus level of serum cytokines may not predict severity of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24024021 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:157
| ACCESS NO | 101266 |
| GENE | IGHE (IgE) |
| DESCRIPTION | Immunoglobulin E |
| NCBI ENTREZ ACCESS NO | 3497 |
| UNIPROT ACCESS NO | P01854 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Cord blood |
| TECHNIQUES | Pharmacia UniCAP system |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | An elevated cord blood IgE level modestly correlates with elevated total IgE and is associated with a slightly higher likelihood of allergic sensitization among young adults. However cord IgE is not a strong predictor of clinical allergic disorders in this age group. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21354027 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IgE [XTE4] for Human |
Record No:158
| ACCESS NO | 101275 |
| GENE | IL8 |
| DESCRIPTION | Interleukin 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Blood |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased expression in rapid onset asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20832159 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Mouse/Human |
Record No:159
| ACCESS NO | 101278 |
| GENE | IL-4 |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma (The effect of aspirin desensitization) |
| SAMPLE | Sputum |
| TECHNIQUES | LINCOplex premixed kit |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Decreased significantly after aspirin treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20728206 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:160
| ACCESS NO | 101282 |
| GENE | IL4 |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy (food allergy caused due to milk egg etc) |
| SAMPLE | Peripheral Blood Mononuclear cell. |
| TECHNIQUES | RT PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Significantly increased in infants with milk allergy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20451041 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Mouse/Human |
Record No:161
| ACCESS NO | 101283 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | Q16552 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthmatic Airways |
| SAMPLE | Sputum |
| TECHNIQUES | RT PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Promotes differentiation of CD4+ T cells and is elevated in induced sputum. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205953 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:162
| ACCESS NO | 101284 |
| GENE | IL13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthmatic Airway |
| SAMPLE | Sputum |
| TECHNIQUES | RT PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Involved in mucus production and is elevated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205953 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:163
| ACCESS NO | 101285 |
| GENE | IL-1 beta |
| DESCRIPTION | Interleukin 1 Beta |
| NCBI ENTREZ ACCESS NO | 3553 |
| UNIPROT ACCESS NO | P01584 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in children |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0001051 |
| MONCLONAL ANTIBODY | Anti-IL1 beta Human |
Record No:164
| ACCESS NO | 101286 |
| GENE | IL-2 |
| DESCRIPTION | Interleukin 2 receptor alpha |
| NCBI ENTREZ ACCESS NO | 3558 |
| UNIPROT ACCESS NO | P60568 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in children |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0001029 |
| MONCLONAL ANTIBODY | Anti-IL2 for Human |
Record No:165
| ACCESS NO | 101287 |
| GENE | IL-4 |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in children |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:166
| ACCESS NO | 101288 |
| GENE | IL-6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in children |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | N/A |
Record No:167
| ACCESS NO | 101289 |
| GENE | IL-13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in children |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:168
| ACCESS NO | 101290 |
| GENE | IFN- gamma |
| DESCRIPTION | Interferon Gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in children |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | Anti-Interferon gamma for Mouse/Human |
Record No:169
| ACCESS NO | 101297 |
| GENE | IP-10 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 10 |
| NCBI ENTREZ ACCESS NO | 3627 |
| UNIPROT ACCESS NO | P02778 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in children |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | Anti-IP10 for Human |
Record No:170
| ACCESS NO | 101304 |
| GENE | IL-8 |
| DESCRIPTION | Interleukin-8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Childhood asthma |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19788537 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human/Rabbit/Pig |
Record No:171
| ACCESS NO | 101305 |
| GENE | IL-5 |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in teenagers |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Time resolved flourimetry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Highly expressed in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19733295 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Mouse/Human |
Record No:172
| ACCESS NO | 101306 |
| GENE | IL-10 |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 3586 |
| UNIPROT ACCESS NO | P22301 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in teenagers |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Time resolved flourimetry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | A non TH2 cytokine but highly expressed in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19733295 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | N/A |
Record No:173
| ACCESS NO | 101307 |
| GENE | IL-12 |
| DESCRIPTION | Interleukin 12 |
| NCBI ENTREZ ACCESS NO | N/A |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in teenagers |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Time resolved flourimetry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It plays a key role in Th1 polarization. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19733295 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:174
| ACCESS NO | 101308 |
| GENE | IL-13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in teenagers |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Time resolved flourimetry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Highly expressed in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19733295 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human/Rat |
Record No:175
| ACCESS NO | 101309 |
| GENE | IFN- gamma |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in teenagers |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Time resolved flourimetry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | A non TH2 cytokine but highly expressed in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19733295 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | N/A |
Record No:176
| ACCESS NO | 101310 |
| GENE | IL-4 |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in teenagers |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Increased expression in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19733295 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti IL4 for Human |
Record No:177
| ACCESS NO | 101312 |
| GENE | IL8 |
| DESCRIPTION | Interleukin-8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe and non severe asthma |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Did not show any marked expression change in severe and non severe asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19622091 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | N/A |
Record No:178
| ACCESS NO | 101313 |
| GENE | IL13 |
| DESCRIPTION | Interleukin-13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe and non severe asthma |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Did not show any marked expression change in severe and non severe asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19622091 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human/Rat |
Record No:179
| ACCESS NO | 101326 |
| GENE | IL1RN |
| DESCRIPTION | Interleukin 1 receptor antagonist isoform |
| NCBI ENTREZ ACCESS NO | 3557 |
| UNIPROT ACCESS NO | P18510 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy(Comparison of Dendritic cell proteome in atopic and non atopic patients) |
| SAMPLE | Dendritic cell |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in Immune response.Differentially expressed in atopic individuals after administering active and inactive DerP1. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19494521 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:180
| ACCESS NO | 101339 |
| GENE | iNOS |
| DESCRIPTION | Nitric oxide synthase 2 inducible |
| NCBI ENTREZ ACCESS NO | 18126 |
| UNIPROT ACCESS NO | P29477 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Asthma (Effect of andrographolide on NF kappa beta pathway in asthma) |
| SAMPLE | Bronchial Epithelial cells |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Strongly downregulated after andrographolide treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19201922 |
| DRUG TARGET | BE0000005 |
| MONCLONAL ANTIBODY | Anti-iNOS for Mouse/Human |
Record No:181
| ACCESS NO | 101340 |
| GENE | IL-6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 16193 |
| UNIPROT ACCESS NO | P08505 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Asthma (Effect of andrographolide on NF kappa beta pathway in asthma) |
| SAMPLE | Bronchial Epithelial cells |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Andrographolide blocked the upregulation of IL6. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19201922 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | N/A |
Record No:182
| ACCESS NO | 101341 |
| GENE | IL-8 |
| DESCRIPTION | Interleukin 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Asthma (Effect of andrographolide on NF kappa beta pathway in asthma) |
| SAMPLE | Bronchial Epithelial cells |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Andrographolide blocked the upregulation of IL8. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19201922 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human/Pig |
Record No:183
| ACCESS NO | 101343 |
| GENE | IL-4 |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 16189 |
| UNIPROT ACCESS NO | P07750 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Asthma (Effect of andrographolide on NF kappa beta pathway in asthma) |
| SAMPLE | Thoracic Lymph node cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expression lowered after Andrographolide treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19201922 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti IL4 for Human |
Record No:184
| ACCESS NO | 101344 |
| GENE | IL-5 |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 16191 |
| UNIPROT ACCESS NO | P04401 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Asthma (Effect of andrographolide on NF kappa beta pathway in asthma) |
| SAMPLE | Thoracic Lymph node cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expression lowered after Andrographolide treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19201922 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Mouse/Human |
Record No:185
| ACCESS NO | 101345 |
| GENE | IL-13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 16163 |
| UNIPROT ACCESS NO | P20109 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Asthma (Effect of andrographolide on NF kappa beta pathway in asthma) |
| SAMPLE | Thoracic Lymph node cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expression lowered after Andrographolide treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19201922 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Mouse |
Record No:186
| ACCESS NO | 101347 |
| GENE | IFN- gamma |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 15978 |
| UNIPROT ACCESS NO | P01580 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Asthma (Effect of andrographolide on NF kappa beta pathway in asthma) |
| SAMPLE | Thoracic Lymph node cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expression increased after Andrographolide treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19201922 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | Anti-Interferon gamma for Mouse/Human |
Record No:187
| ACCESS NO | 101360 |
| GENE | IgG1 |
| DESCRIPTION | Immunoglobulin heavy chain 4 protein |
| NCBI ENTREZ ACCESS NO | 16017 |
| UNIPROT ACCESS NO | Q5F2I1 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in Chronic asthma. Indicates hyperplasia of mucous glands. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:188
| ACCESS NO | 101409 |
| GENE | Il4i1 |
| DESCRIPTION | Interleukin 4 induced 1 |
| NCBI ENTREZ ACCESS NO | 14204 |
| UNIPROT ACCESS NO | O09046 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0004566 |
| MONCLONAL ANTIBODY | N/A |
Record No:189
| ACCESS NO | 101411 |
| GENE | Il1rn |
| DESCRIPTION | Interleukin 1 receptor antagonist |
| NCBI ENTREZ ACCESS NO | 16181 |
| UNIPROT ACCESS NO | P25085 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL1RA for Mouse/Rat/Human |
Record No:190
| ACCESS NO | 101419 |
| GENE | Il1b |
| DESCRIPTION | Interleukin 1 beta |
| NCBI ENTREZ ACCESS NO | 16176 |
| UNIPROT ACCESS NO | P10749 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0001051 |
| MONCLONAL ANTIBODY | Anti-IL1 beta for Mouse |
Record No:191
| ACCESS NO | 101426 |
| GENE | Igsf6 |
| DESCRIPTION | Immunoglobulin superfamily member 6 |
| NCBI ENTREZ ACCESS NO | 80719 |
| UNIPROT ACCESS NO | P0C6B7 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IGSF6 for Human |
Record No:192
| ACCESS NO | 101430 |
| GENE | Il1r2 |
| DESCRIPTION | Interleukin 1 receptor type II |
| NCBI ENTREZ ACCESS NO | 16178 |
| UNIPROT ACCESS NO | P27931 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:193
| ACCESS NO | 101450 |
| GENE | Itgam |
| DESCRIPTION | Integrin alpha M |
| NCBI ENTREZ ACCESS NO | 16409 |
| UNIPROT ACCESS NO | E9Q604 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3hours and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD11b for Mouse/Rabbit/Human |
Record No:194
| ACCESS NO | 101459 |
| GENE | Ikbke |
| DESCRIPTION | Inhibitor of kappaB kinase epsilon |
| NCBI ENTREZ ACCESS NO | 56489 |
| UNIPROT ACCESS NO | Q9R0T8 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of fungal allergen induction in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IKKi/IKKe for Human |
Record No:195
| ACCESS NO | 101462 |
| GENE | Ifit1 |
| DESCRIPTION | Interferon-induced protein with tetratricopeptide repeats 1 |
| NCBI ENTREZ ACCESS NO | 15957 |
| UNIPROT ACCESS NO | Q64282 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IFIT1 for Human |
Record No:196
| ACCESS NO | 101480 |
| GENE | Il1f9 |
| DESCRIPTION | Interleukin 1 family member 9 |
| NCBI ENTREZ ACCESS NO | 215257 |
| UNIPROT ACCESS NO | Q3U0P4 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of fungal allergen challenge in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL36 gamma for Human |
Record No:197
| ACCESS NO | 101485 |
| GENE | Il17ra |
| DESCRIPTION | Interleukin-17 receptor A precursor |
| NCBI ENTREZ ACCESS NO | 16172 |
| UNIPROT ACCESS NO | Q60943 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Expressed in allergen induced asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL17A Receptor for Mouse/Human |
Record No:198
| ACCESS NO | 101501 |
| GENE | Irf5 |
| DESCRIPTION | Interferon regulatory factor 5 |
| NCBI ENTREZ ACCESS NO | 27056 |
| UNIPROT ACCESS NO | P56477 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IRF5 for mouse/Human |
Record No:199
| ACCESS NO | 101517 |
| GENE | Irf4 |
| DESCRIPTION | Interferon regulatory factor 4 |
| NCBI ENTREZ ACCESS NO | 16364 |
| UNIPROT ACCESS NO | Q9QUI6 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MUM1 for Human |
Record No:200
| ACCESS NO | 101535 |
| GENE | IFN-gamma |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Childhood asthma |
| SAMPLE | Exhaled breath condensate |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Has pro inflammatory effects and is responsible for recruiting infammatory cytokines . Higher expression in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17845410 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | Anti-Interferon gamma for Human |
Record No:201
| ACCESS NO | 101536 |
| GENE | IL-4 |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Childhood asthma |
| SAMPLE | Exhaled breath condensate |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Higher expression in asthmatics compared to controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17845410 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:202
| ACCESS NO | 101537 |
| GENE | IP-10 |
| DESCRIPTION | Induced Protein 10 |
| NCBI ENTREZ ACCESS NO | 3627 |
| UNIPROT ACCESS NO | P02778 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by Virus |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Highly expressed in virus induced asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17628646 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | Anti-IP10 for Mouse/Human |
Record No:203
| ACCESS NO | 101539 |
| GENE | IL-6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by Virus |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expressed in virus induced asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17628646 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | N/A |
Record No:204
| ACCESS NO | 101540 |
| GENE | IL-8(CXCL8) |
| DESCRIPTION | Interleukin 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by Virus |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expressed in virus induced asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17628646 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human/Pig |
Record No:205
| ACCESS NO | 101544 |
| GENE | Icam-1 |
| DESCRIPTION | Intercellular adhesion molecule 1 |
| NCBI ENTREZ ACCESS NO | 15894 |
| UNIPROT ACCESS NO | P13597 |
| ORGANISM | Female Balb/c Mice |
| DISEASE PHENOTYPE | Asthma(Effect of Glycogen synthase kinase-3 beta inhibition on asthma) |
| SAMPLE | Lung tissue |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Significantly upregulated after OVA challenge in mRNA. However decreased after Gsk-3b inhibitor induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17556716 |
| DRUG TARGET | BE0001085 |
| MONCLONAL ANTIBODY | Anti-ICAM1 for Human |
Record No:206
| ACCESS NO | 101549 |
| GENE | IL-6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 16193 |
| UNIPROT ACCESS NO | P08505 |
| ORGANISM | Female Balb/c Mice |
| DISEASE PHENOTYPE | Asthma(Effect of Glycogen synthase kinase-3 beta inhibition on asthma) |
| SAMPLE | Lung tissue |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Gsk3b inhibitor blocked the expression of IL6. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17556716 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | N/A |
Record No:207
| ACCESS NO | 101550 |
| GENE | IL-8 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 15 |
| NCBI ENTREZ ACCESS NO | 20309 |
| UNIPROT ACCESS NO | Q9WVL7 |
| ORGANISM | Female Balb/c Mice |
| DISEASE PHENOTYPE | Asthma(Effect of Glycogen synthase kinase-3 beta inhibition on asthma) |
| SAMPLE | Lung tissue |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Gsk3b inhibitor blocked the expression of IL8. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17556716 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human/Pig |
Record No:208
| ACCESS NO | 101645 |
| GENE | IFNGR1 |
| DESCRIPTION | IFN-g receptor 1 |
| NCBI ENTREZ ACCESS NO | 3459 |
| UNIPROT ACCESS NO | P15260 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Insect allergy(Bee venom immunotherapy) |
| SAMPLE | Peripheral Blood Mononuclear cells |
| TECHNIQUES | Gene chip microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Involved in osteopontin regulatory pathway. Expressed after venom immunotherapy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15867867 |
| DRUG TARGET | BE0000711 |
| MONCLONAL ANTIBODY | Anti-IFNGR1 for Human |
Record No:209
| ACCESS NO | 101651 |
| GENE | Inmt |
| DESCRIPTION | Thioether S-methyltransferase |
| NCBI ENTREZ ACCESS NO | 21743 |
| UNIPROT ACCESS NO | P40936 |
| ORGANISM | Male BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | 2D electrophoresis and MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16100447 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-INMT for Mouse/Rat/Human |
Record No:210
| ACCESS NO | 101662 |
| GENE | IL-6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy (Perinatal immune responses) |
| SAMPLE | PBMC |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Neonatal responses were lower for children positive to Fel d1. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 14616132 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | N/A |
Record No:211
| ACCESS NO | 101663 |
| GENE | IL-13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy (Perinatal immune responses) |
| SAMPLE | PBMC |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Lower expression in children at birth who show positive SPT to house dust mite. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 14616132 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:212
| ACCESS NO | 101664 |
| GENE | IFN- gamma |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy (Perinatal immune responses) |
| SAMPLE | PBMC |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Weaker IFN gamma response in neonatal patients having a history to allergy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 14616132 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | Anti-Interferon gamma for Human |
Record No:213
| ACCESS NO | 101665 |
| GENE | IL-5 |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy (Perinatal immune responses) |
| SAMPLE | PBMC |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Downregulated in children having no family history of allergy and upregulated in children having family history of allergy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 14616132 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:214
| ACCESS NO | 101670 |
| GENE | Icam1 (ICAM-1) |
| DESCRIPTION | Intercellular adhesion molecule 1 |
| NCBI ENTREZ ACCESS NO | 15894 |
| UNIPROT ACCESS NO | P13597 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and its modulation by Minocycline |
| SAMPLE | Lung cells |
| TECHNIQUES | Real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Minocycline marked reduction in the expression of this NF kappa Beta dependent gene. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23184953 |
| DRUG TARGET | BE0001085 |
| MONCLONAL ANTIBODY | Anti-ICAM1 [MEM-111] for rat/Human |
Record No:215
| ACCESS NO | 101675 |
| GENE | Igfbp3 (IGFBP-3) |
| DESCRIPTION | Insulin-like growth factor binding protein 3 |
| NCBI ENTREZ ACCESS NO | 16009 |
| UNIPROT ACCESS NO | P47878 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and its protection by IGFBP-3 treatment |
| SAMPLE | Lung tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | Immunoblot and immunohistochemistry |
| OMICS | Proteomics |
| STUDY | Low Throughput |
| COMMENTS | This protein was found to be down regulated significantly upon ovalbumin challenge. IGFBP-3 treatment inhibits airway inflammation and hyper-responsiveness via an IGF-independent mechanism that involves activation of IGFBP-3R signaling and cross-talk with NF- B signaling. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21383009 |
| DRUG TARGET | BE0000970 |
| MONCLONAL ANTIBODY | Anti-IGFBP3 for Human |
Record No:216
| ACCESS NO | 101676 |
| GENE | Icam1 (ICAM-1) |
| DESCRIPTION | Intercellular adhesion molecule 1 |
| NCBI ENTREZ ACCESS NO | 15894 |
| UNIPROT ACCESS NO | P13597 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and its protection by IGFBP-3 treatment |
| SAMPLE | Lung tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | Immunoblot |
| OMICS | Proteomics |
| STUDY | Low Throughput |
| COMMENTS | IGFBP-3 treatment blocks TNF- alpha induced ICAM-1 expression in NF-kappa B signaling cascades upon allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21383009 |
| DRUG TARGET | BE0001085 |
| MONCLONAL ANTIBODY | Anti-ICAM1 [MEM-111] for rat/Human |
Record No:217
| ACCESS NO | 101679 |
| GENE | Il4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 16189 |
| UNIPROT ACCESS NO | P07750 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and its protection by IGFBP-3 treatment |
| SAMPLE | Lung tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | Immunoblot and ELISA |
| OMICS | Proteomics |
| STUDY | Low Throughput |
| COMMENTS | This proinflammatory protein is upregulated in lung tissue upon allergen challenge. However in IGFBP-3 transgenic mice this protein is significantly down regulated even after allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21383009 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 [MP4-25D2] for human |
Record No:218
| ACCESS NO | 101680 |
| GENE | Il5 (IL-5) |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 16191 |
| UNIPROT ACCESS NO | P04401 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and its protection by IGFBP-3 treatment |
| SAMPLE | Lung tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | Immunoblot and ELISA |
| OMICS | Proteomics |
| STUDY | Low Throughput |
| COMMENTS | This proinflammatory protein is upregulated in lung tissue upon allergen challenge. However in IGFBP-3 transgenic mice this protein is significantly down regulated even after allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21383009 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 [JES1-39D10] for Human |
Record No:219
| ACCESS NO | 101681 |
| GENE | Il13 (IL-13) |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 16163 |
| UNIPROT ACCESS NO | P20109 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and its protection by IGFBP-3 treatment |
| SAMPLE | Lung tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | Immunoblot and ELISA |
| OMICS | Proteomics |
| STUDY | Low Throughput |
| COMMENTS | This proinflammatory protein is upregulated in lung tissue upon allergen challenge. However in IGFBP-3 transgenic mice this protein is significantly down regulated even after allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21383009 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 [JES10-5A2] for Human |
Record No:220
| ACCESS NO | 101698 |
| GENE | IGFBP2 |
| DESCRIPTION | Insulin-like growth factor-binding protein 2 |
| NCBI ENTREZ ACCESS NO | 3485 |
| UNIPROT ACCESS NO | P18065 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This growth factor is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IGFBP2 [EPR3380(2)] for human |
Record No:221
| ACCESS NO | 101699 |
| GENE | IGFBP3 |
| DESCRIPTION | Insulin-like growth factor-binding protein 3 |
| NCBI ENTREZ ACCESS NO | 3486 |
| UNIPROT ACCESS NO | P17936 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This growth factor is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000970 |
| MONCLONAL ANTIBODY | Anti-IGFBP3 for Human |
Record No:222
| ACCESS NO | 101703 |
| GENE | IGFBP6 |
| DESCRIPTION | Insulin-like growth factor-binding protein 6 |
| NCBI ENTREZ ACCESS NO | 3489 |
| UNIPROT ACCESS NO | P24592 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This growth factor is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IGFBP6 for Human |
Record No:223
| ACCESS NO | 101719 |
| GENE | ITIH1 |
| DESCRIPTION | Inter-alpha-trypsin inhibitor heavy chain H1 |
| NCBI ENTREZ ACCESS NO | 3697 |
| UNIPROT ACCESS NO | P19827 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protease inhibitor is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:224
| ACCESS NO | 101726 |
| GENE | ITIH3 |
| DESCRIPTION | Inter-alpha-trypsin inhibitor heavy chain 3 |
| NCBI ENTREZ ACCESS NO | 3699 |
| UNIPROT ACCESS NO | Q06033 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protease inhibitor is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:225
| ACCESS NO | 101767 |
| GENE | ITLN1 |
| DESCRIPTION | Intelectin (endothelial lectin HL-1) |
| NCBI ENTREZ ACCESS NO | 55600 |
| UNIPROT ACCESS NO | Q8WWA0 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This local matrix protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-ITLN1 for Human |
Record No:226
| ACCESS NO | 101846 |
| GENE | IGJ |
| DESCRIPTION | Immunoglobulin J chain/IGJ |
| NCBI ENTREZ ACCESS NO | 3512 |
| UNIPROT ACCESS NO | P01591 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis |
| SAMPLE | Nasal mucus |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It showed 0.7 fold expression change in rhinitis patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24290289 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:227
| ACCESS NO | 101911 |
| GENE | IDE |
| DESCRIPTION | Insulin-degrading enzyme |
| NCBI ENTREZ ACCESS NO | 3416 |
| UNIPROT ACCESS NO | P14735 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | BE0001183 |
| MONCLONAL ANTIBODY | Anti-Insulin degrading enzyme / IDE for Human |
Record No:228
| ACCESS NO | 101915 |
| GENE | ITGA6 |
| DESCRIPTION | Integrin a-6 precursor |
| NCBI ENTREZ ACCESS NO | 3655 |
| UNIPROT ACCESS NO | P23229 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Integrin alpha 6 for Human |
Record No:229
| ACCESS NO | 101933 |
| GENE | ITGB7 |
| DESCRIPTION | Integrin b-7 |
| NCBI ENTREZ ACCESS NO | 3695 |
| UNIPROT ACCESS NO | P26010 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | BE0003414 |
| MONCLONAL ANTIBODY | Anti-Integrin beta 7 for Mouse/Human |
Record No:230
| ACCESS NO | 101956 |
| GENE | IBRDC3 |
| DESCRIPTION | IBR domain containing 3 |
| NCBI ENTREZ ACCESS NO | 127544 |
| UNIPROT ACCESS NO | Q6ZMZ0 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:231
| ACCESS NO | 101963 |
| GENE | IGF2BP2 |
| DESCRIPTION | Insulin-like growth factor 2 mRNA binding protein 2 |
| NCBI ENTREZ ACCESS NO | 10644 |
| UNIPROT ACCESS NO | Q9Y6M1 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthmatic children. Involved in immune and lymphatic system development. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IGF2BP2 for Mouse/Rat/Human |
Record No:232
| ACCESS NO | 101969 |
| GENE | IFN- gamma (IFNG) |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy (Immunotherapy of pollen allergy) |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Flow cytometry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased after specific immunotherapy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24834772 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | Anti-Interferon gamma for Mouse/Rat/Human |
Record No:233
| ACCESS NO | 101970 |
| GENE | IL-10 |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 3586 |
| UNIPROT ACCESS NO | P22301 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy (Immunotherapy of pollen allergy) |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Flow cytometry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased after specific immunotherapy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24834772 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | N/A |
Record No:234
| ACCESS NO | 101992 |
| GENE | IQCG |
| DESCRIPTION | IQ motif containing G |
| NCBI ENTREZ ACCESS NO | 84223 |
| UNIPROT ACCESS NO | Q9H095 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in patients with allergic rhinitis in the upper airways. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:235
| ACCESS NO | 102019 |
| GENE | IL13RA2 |
| DESCRIPTION | Interleukin 13 receptor alpha 2 |
| NCBI ENTREZ ACCESS NO | 3598 |
| UNIPROT ACCESS NO | Q14627 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Primary nasal and bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in upper airways in allergic rhinitis patients with or without asthma.(Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | BE0002421 |
| MONCLONAL ANTIBODY | Anti-IL13 receptor alpha 2 for Rabbit/Human |
Record No:236
| ACCESS NO | 102020 |
| GENE | IL1B |
| DESCRIPTION | Interleukin 1 beta |
| NCBI ENTREZ ACCESS NO | 3553 |
| UNIPROT ACCESS NO | P01584 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Primary nasal and bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in upperairways of allergic rhinitis patients without asthma and downregulated in upper airways of patients with asthma. (Data in supplimentary table.) |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | BE0001051 |
| MONCLONAL ANTIBODY | Anti-IL1 beta for Human |
Record No:237
| ACCESS NO | 102021 |
| GENE | IL8(CXCL8) |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Primary nasal and bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Downregulated in upperairways of patients with allergic rhinitis and asthma.(Data in supplimentary table.) |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Mouse/Human |
Record No:238
| ACCESS NO | 102034 |
| GENE | IL33 |
| DESCRIPTION | Interleukin 33 |
| NCBI ENTREZ ACCESS NO | 90865 |
| UNIPROT ACCESS NO | O95760 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. Induces Th2 associated cytokines.(Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL33 for Mouse/Human |
Record No:239
| ACCESS NO | 102055 |
| GENE | IL13RA2 |
| DESCRIPTION | Interleukin 13 receptor alpha 2 |
| NCBI ENTREZ ACCESS NO | 3598 |
| UNIPROT ACCESS NO | Q14627 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Nasal epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | BE0002421 |
| MONCLONAL ANTIBODY | N/A |
Record No:240
| ACCESS NO | 102056 |
| GENE | IL1R2 |
| DESCRIPTION | Interleukin 1 receptor type II |
| NCBI ENTREZ ACCESS NO | 7850 |
| UNIPROT ACCESS NO | P27930 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Nasal epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL1 Receptor II for Human |
Record No:241
| ACCESS NO | 102057 |
| GENE | IRX4 |
| DESCRIPTION | Iroquois homeobox 4 |
| NCBI ENTREZ ACCESS NO | 50805 |
| UNIPROT ACCESS NO | P78413 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Nasal epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:242
| ACCESS NO | 102064 |
| GENE | IL4(Il-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Intermittent allergic rhinitis |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased in monozygotic twins suffering from allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | GSE37146 |
| REFERENCE | 22515200 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Mouse |
Record No:243
| ACCESS NO | 102065 |
| GENE | IL5(IL-5) |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Intermittent allergic rhinitis |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased in monozygotic twins suffering from allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | GSE37146 |
| REFERENCE | 22515200 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Mouse/Human |
Record No:244
| ACCESS NO | 102066 |
| GENE | IL13(IL-13) |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Intermittent allergic rhinitis |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased in monozygotic twins suffering from allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | GSE37146 |
| REFERENCE | 22515200 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Mouse/Rat/Human |
Record No:245
| ACCESS NO | 102067 |
| GENE | IL17RB |
| DESCRIPTION | Interleukin 15 receptor B |
| NCBI ENTREZ ACCESS NO | 55540 |
| UNIPROT ACCESS NO | Q9NRM6 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Intermittent allergic rhinitis |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Increased in monozygotic twins suffering from allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | GSE37146 |
| REFERENCE | 22515200 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL17B Receptor for Mouse |
Record No:246
| ACCESS NO | 102068 |
| GENE | IL4R |
| DESCRIPTION | Interleukin 4 receptor |
| NCBI ENTREZ ACCESS NO | 3566 |
| UNIPROT ACCESS NO | P24394 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Intermittent allergic rhinitis |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Increased in monozygotic twins suffering from allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | GSE37146 |
| REFERENCE | 22515200 |
| DRUG TARGET | BE0002420 |
| MONCLONAL ANTIBODY | Anti-IL4R for Human |
Record No:247
| ACCESS NO | 102076 |
| GENE | IL-1F6 |
| DESCRIPTION | IL-1 family member 6 |
| NCBI ENTREZ ACCESS NO | 27179 |
| UNIPROT ACCESS NO | Q9UHA7 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in inflammation and immunoregulation. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:248
| ACCESS NO | 102104 |
| GENE | IL-2R |
| DESCRIPTION | IL-2 receptor |
| NCBI ENTREZ ACCESS NO | 3559 |
| UNIPROT ACCESS NO | P01589 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthma. Involved in TH2 differentiation and Treg homeostasis. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | BE0000658 |
| MONCLONAL ANTIBODY | N/A |
Record No:249
| ACCESS NO | 102110 |
| GENE | ID2 |
| DESCRIPTION | Inhibitor of DNA binding 2 |
| NCBI ENTREZ ACCESS NO | 3398 |
| UNIPROT ACCESS NO | Q02363 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthma. Involved in Th2/IgE regulation. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-ID2 for Human |
Record No:250
| ACCESS NO | 102111 |
| GENE | IL-13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in asthma. Involved in Th2 regulation and function. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:251
| ACCESS NO | 102112 |
| GENE | IL-17RB |
| DESCRIPTION | Interleukin 17 receptor B |
| NCBI ENTREZ ACCESS NO | 55540 |
| UNIPROT ACCESS NO | Q9NRM6 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthma. Promotes Th2 memory expansion and function. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL17B Receptor for Human |
Record No:252
| ACCESS NO | 102113 |
| GENE | IL-4R |
| DESCRIPTION | Interleukin 4 receptor |
| NCBI ENTREZ ACCESS NO | 3566 |
| UNIPROT ACCESS NO | P24394 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in asthma. Involved in Th2 differentiation and Th2 memory stabilization. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | BE0002420 |
| MONCLONAL ANTIBODY | Anti-IL4R for Human |
Record No:253
| ACCESS NO | 102114 |
| GENE | IL-5 |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in asthma. Involved in Th2 regulation and function. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:254
| ACCESS NO | 102118 |
| GENE | IKZF4 |
| DESCRIPTION | IKAROS family zinc finger 4 |
| NCBI ENTREZ ACCESS NO | 64375 |
| UNIPROT ACCESS NO | Q9H2S9 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in atopic asthma. Involved in Treg expression and function. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-ZNFN1A4 for Mouse/Rat/Human |
Record No:255
| ACCESS NO | 102119 |
| GENE | ITK |
| DESCRIPTION | IL2-inducible T cell kinase |
| NCBI ENTREZ ACCESS NO | 3702 |
| UNIPROT ACCESS NO | Q08881 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in atopic asthma.Involved in Th2 differentiation and activation. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | BE0001341 |
| MONCLONAL ANTIBODY | Anti-ITK for Human |
Record No:256
| ACCESS NO | 102123 |
| GENE | IKZF1 |
| DESCRIPTION | IKAROS family zinc finger 1 |
| NCBI ENTREZ ACCESS NO | 10320 |
| UNIPROT ACCESS NO | Q13422 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentialy expressed in asthma. Involved in transcriptional regulation. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Ikaros for Human |
Record No:257
| ACCESS NO | 102134 |
| GENE | IMMT |
| DESCRIPTION | Inner membrane protein mitochondrial |
| NCBI ENTREZ ACCESS NO | 10989 |
| UNIPROT ACCESS NO | Q16891 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Differentialy expressed in asthma. A lipd raft protein. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:258
| ACCESS NO | 102143 |
| GENE | IGHG1 |
| DESCRIPTION | Immunoglobulin heavy constant gamma 1 |
| NCBI ENTREZ ACCESS NO | 3500 |
| UNIPROT ACCESS NO | P01857 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Bronchial Biopsy |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | GSE41649 |
| REFERENCE | 19842841 |
| DRUG TARGET | BE0002815 |
| MONCLONAL ANTIBODY | Anti-Human IgG for Human |
Record No:259
| ACCESS NO | 102144 |
| GENE | IGKC |
| DESCRIPTION | Immunoglobulin kappa constant |
| NCBI ENTREZ ACCESS NO | 3514 |
| UNIPROT ACCESS NO | P01834 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Bronchial Biopsy |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | GSE41649 |
| REFERENCE | 19842841 |
| DRUG TARGET | BE0003836 |
| MONCLONAL ANTIBODY | Anti-Kappa light chain for Human |