BROWSE RESULT OF K
| 26 Records |
| ACCESS NO | 100014 |
| GENE | KIAA0101 |
| DESCRIPTION | KIAA0101 |
| NCBI ENTREZ ACCESS NO | 9768 |
| UNIPROT ACCESS NO | Q15004 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in low SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-KIAA0101 for Human |
Record No:2
| ACCESS NO | 100039 |
| GENE | KDM5D (SMCY) |
| DESCRIPTION | Lysine (K)-specific demethylase 5D |
| NCBI ENTREZ ACCESS NO | 8284 |
| UNIPROT ACCESS NO | Q9BY66 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in high SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | BE0002215 |
| MONCLONAL ANTIBODY | N/A |
Record No:3
| ACCESS NO | 100068 |
| GENE | KIR2DL4 |
| DESCRIPTION | Killer cell immunoglobulin-like receptor - two domains and long cytoplasmic tail 4 |
| NCBI ENTREZ ACCESS NO | 3805 |
| UNIPROT ACCESS NO | Q99706 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in innate immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-KIR2DL4 for Human |
Record No:4
| ACCESS NO | 100198 |
| GENE | KLF4 |
| DESCRIPTION | Kruppel-like factor 4 |
| NCBI ENTREZ ACCESS NO | 9314 |
| UNIPROT ACCESS NO | O43474 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an transcription factor significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-KLF4 for Mouse/Human |
Record No:5
| ACCESS NO | 100213 |
| GENE | KRT5 |
| DESCRIPTION | Cytokeratin 5 |
| NCBI ENTREZ ACCESS NO | 3852 |
| UNIPROT ACCESS NO | P13647 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene codes for a metabolic enzyme significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Cytokeratin 5 for Mouse/Human |
Record No:6
| ACCESS NO | 100214 |
| GENE | KRT4 |
| DESCRIPTION | Cytokeratin 4 |
| NCBI ENTREZ ACCESS NO | 3851 |
| UNIPROT ACCESS NO | P19013 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene codes for a metabolic enzyme significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Cytokeratin 4 for Human |
Record No:7
| ACCESS NO | 100237 |
| GENE | KARCA1 |
| DESCRIPTION | Kelch/ankyrin repeat containing cyclin A1 interacting protein |
| NCBI ENTREZ ACCESS NO | 126823 |
| UNIPROT ACCESS NO | Q8NEP7 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:8
| ACCESS NO | 100241 |
| GENE | KANK4 (ARD38) |
| DESCRIPTION | Ankyrin repeat domain 38 |
| NCBI ENTREZ ACCESS NO | 163782 |
| UNIPROT ACCESS NO | Q5T7N3 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:9
| ACCESS NO | 100429 |
| GENE | KRT17 |
| DESCRIPTION | Cytokeratin 17 |
| NCBI ENTREZ ACCESS NO | 3872 |
| UNIPROT ACCESS NO | Q04695 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | bronchial epithelial cells stimulated with TGF bet |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It regulates cell growth. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20219718 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Cytokeratin 17 for Human |
Record No:10
| ACCESS NO | 100469 |
| GENE | KLF15 |
| DESCRIPTION | Kruppel-like factor 15 |
| NCBI ENTREZ ACCESS NO | 28999 |
| UNIPROT ACCESS NO | Q9UIH9 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Airway smooth muscle cell (ASM) line |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is already known to modulate vascular smooth and cardiac muscle function from earlier studies. In the present article overexpression of this gene reduced human Asm proliferation. But in KLF15 knock out mice the ASM proliferation was found to be increased . It is also upregulated upon glucocoricoid treatment. Hence this gene can be considered as candidate marker of glucocorticoid receptor regulated gene network. |
| GEO_PRIDE_ACCESS_NO | GSE3946 |
| REFERENCE | 21257922 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-KLF15 [EPR14131] for Mouse/Rat/Human |
Record No:11
| ACCESS NO | 100701 |
| GENE | Klk1 |
| DESCRIPTION | Kallikrein 1 |
| NCBI ENTREZ ACCESS NO | 16612 |
| UNIPROT ACCESS NO | P15947 |
| ORGANISM | TSLP TG mice and BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid Broncho Alveol |
| TECHNIQUES | LC-MS/MS and Western blot and qRT PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Serine protease involved in producing mediators of airway hyperresponsiveness. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22837640 |
| DRUG TARGET | BE0001091 |
| MONCLONAL ANTIBODY | N/A |
Record No:12
| ACCESS NO | 100744 |
| GENE | KNS2 |
| DESCRIPTION | Kinesin light chain 1 |
| NCBI ENTREZ ACCESS NO | 3831 |
| UNIPROT ACCESS NO | Q07866 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Perpheral blood mononuclear cells |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | A marker of mild asthma was found to be downregulated. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21966607 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-KLC1 for Mouse/Rat/Human |
Record No:13
| ACCESS NO | 100807 |
| GENE | Kcnj |
| DESCRIPTION | ATP sensitive inward rectifier potassium channel 15 |
| NCBI ENTREZ ACCESS NO | 16516 |
| UNIPROT ACCESS NO | O88932 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in both chronic and acute allergen exposure |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:14
| ACCESS NO | 100837 |
| GENE | Klf6 |
| DESCRIPTION | Kruppel-like factor 16 |
| NCBI ENTREZ ACCESS NO | 23849 |
| UNIPROT ACCESS NO | Q8BPQ2 |
| ORGANISM | SWR/J mouse |
| DISEASE PHENOTYPE | Allergic conjunctivitis |
| SAMPLE | Conjunctival Tissues |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in Conjunctiva of allergen induced mice. May play a role in B cell development. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18658092 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:15
| ACCESS NO | 100845 |
| GENE | Kif20a |
| DESCRIPTION | Kinesin family member 20A |
| NCBI ENTREZ ACCESS NO | 19348 |
| UNIPROT ACCESS NO | P97329 |
| ORGANISM | SWR/J mouse |
| DISEASE PHENOTYPE | Allergic conjunctivitis |
| SAMPLE | Conjunctival Tissues |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in the conjunctiva. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18658092 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:16
| ACCESS NO | 100916 |
| GENE | Krt8 |
| DESCRIPTION | Keratin 8 |
| NCBI ENTREZ ACCESS NO | 16691 |
| UNIPROT ACCESS NO | P11679 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Present in cytokine and chemokine mediated signalling pathway. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | BE0002105 |
| MONCLONAL ANTIBODY | N/A |
Record No:17
| ACCESS NO | 101033 |
| GENE | KRT13 |
| DESCRIPTION | Keratin type I cytoskeletal 13 |
| NCBI ENTREZ ACCESS NO | 3860 |
| UNIPROT ACCESS NO | P13646 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly upregulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Cytokeratin 13 for Mouse/Rabbit/Human |
Record No:18
| ACCESS NO | 101060 |
| GENE | KNG1 |
| DESCRIPTION | kininogen-1 isoform 2 |
| NCBI ENTREZ ACCESS NO | 3827 |
| UNIPROT ACCESS NO | P01042 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and aspirin tolerance |
| SAMPLE | Plasma |
| TECHNIQUES | 2DE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Expression of this protein is increased in Aspirin-exacerbated respiratory disease (AERD) as compared to aspirin-tolerant asthma (ATA). |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24120690 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-HMW Kininogen for Human |
Record No:19
| ACCESS NO | 101357 |
| GENE | Krt7 |
| DESCRIPTION | Cytokeratin 7 |
| NCBI ENTREZ ACCESS NO | 110310 |
| UNIPROT ACCESS NO | Q9DCV7 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in Chronic asthma. Indicates hyperplasia of mucous glands. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | BE0002459 |
| MONCLONAL ANTIBODY | Anti-Cytokeratin 7 for Mouse/Rat/Human |
Record No:20
| ACCESS NO | 101460 |
| GENE | Klf15 |
| DESCRIPTION | Kruppel-like factor 15 |
| NCBI ENTREZ ACCESS NO | 66277 |
| UNIPROT ACCESS NO | Q9EPW2 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of fungal allergen challenge in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-KLF15 for Human |
Record No:21
| ACCESS NO | 101586 |
| GENE | Kdelr3 |
| DESCRIPTION | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| NCBI ENTREZ ACCESS NO | 105785 |
| UNIPROT ACCESS NO | Q8R1L4 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Present in the endoplasmic reticulum and expressed after IL13induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:22
| ACCESS NO | 101667 |
| GENE | Kcna3 |
| DESCRIPTION | Voltage-gated KV1.3 potassium channel |
| NCBI ENTREZ ACCESS NO | 29731 |
| UNIPROT ACCESS NO | P15384 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Mononuclear cells isolated from Broncho Alveolar L |
| TECHNIQUES | Patch clamp electrophysiology together with flow c |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | KV1.3 channels on CCR7 effector memory T lymphocytes are major players in lung inflammation that characterizes allergic asthma. Blocking KV1.3 channels reduced the severity of an ovalbumin-induced model of asthma in rats and therefore KV1.3 channels are attractive targets for immunomodulation and the treatment of allergic asthma. This study investigated the inhibitory effect of ShK-186 drug on this ion channel to effectively reduce the severity of allergic asthma symptoms. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24644290 |
| DRUG TARGET | BE0004105 |
| MONCLONAL ANTIBODY | Anti-KCNA3 for Mouse/Rat/Human |
Record No:23
| ACCESS NO | 101877 |
| GENE | KRT10 |
| DESCRIPTION | Keratin 10 |
| NCBI ENTREZ ACCESS NO | 3858 |
| UNIPROT ACCESS NO | P13645 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Fibroblast |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic fibroblasts comparative to normal fibroblasts. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15468290 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Cytokeratin 10 for Mouse/Rat/Human |
Record No:24
| ACCESS NO | 101913 |
| GENE | KEL |
| DESCRIPTION | Kell blood group glycoprotein |
| NCBI ENTREZ ACCESS NO | 3792 |
| UNIPROT ACCESS NO | P23276 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Blood Group Kell Antigen for Human |
Record No:25
| ACCESS NO | 102090 |
| GENE | KPNA6 |
| DESCRIPTION | Karyopherin #6 |
| NCBI ENTREZ ACCESS NO | 23633 |
| UNIPROT ACCESS NO | O60684 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Differentially expressed in asthma. Imports STAT3 to the nucleus. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:26
| ACCESS NO | 102124 |
| GENE | KLF3 |
| DESCRIPTION | Kruppel-like factor 3 |
| NCBI ENTREZ ACCESS NO | 51274 |
| UNIPROT ACCESS NO | P57682 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentialy expressed in asthma. May play a role in hematopoesis. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-KLF3 for Human |