BROWSE RESULT OF L
| 66 Records |
| ACCESS NO | 100011 |
| GENE | LPGAT1 |
| DESCRIPTION | Lysophosphatidylglycerol acyltransferase 1 |
| NCBI ENTREZ ACCESS NO | 9926 |
| UNIPROT ACCESS NO | Q92604 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in low SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:2
| ACCESS NO | 100031 |
| GENE | LONPL |
| DESCRIPTION | Lon peptidase 2 |
| NCBI ENTREZ ACCESS NO | 83752 |
| UNIPROT ACCESS NO | Q86WA8 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in high SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:3
| ACCESS NO | 100052 |
| GENE | LTB4R |
| DESCRIPTION | Leukotriene B4 receptor |
| NCBI ENTREZ ACCESS NO | 1241 |
| UNIPROT ACCESS NO | Q15722 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in arachidonic acid/prostagandin metabolism. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Leukotriene B4 Receptor for Human |
Record No:4
| ACCESS NO | 100124 |
| GENE | Lilrb4 |
| DESCRIPTION | Leukocyte immunoglobulin-like receptor subfamily B (member 4) |
| NCBI ENTREZ ACCESS NO | 14728 |
| UNIPROT ACCESS NO | Q64281 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an IL-4 specific immunoglobulin fragment gene induced in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:5
| ACCESS NO | 100131 |
| GENE | Lilrb4 |
| DESCRIPTION | Leukocyte immunoglobulin-like receptor (subfamily B) member 4 |
| NCBI ENTREZ ACCESS NO | 14728 |
| UNIPROT ACCESS NO | Q64281 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an IL-4 specific host immune responsive gene induced in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:6
| ACCESS NO | 100153 |
| GENE | LOXL2 |
| DESCRIPTION | Lysyl oxidase-like 2 |
| NCBI ENTREZ ACCESS NO | 4017 |
| UNIPROT ACCESS NO | Q9Y4K0 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LOXL2 [EPR12733] for Mouse/Rat/Human |
Record No:7
| ACCESS NO | 100168 |
| GENE | LTB |
| DESCRIPTION | Lymphotoxin beta |
| NCBI ENTREZ ACCESS NO | 4050 |
| UNIPROT ACCESS NO | Q06643 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:8
| ACCESS NO | 100223 |
| GENE | LMCD1 |
| DESCRIPTION | LIM and cysteine-rich domains 1 |
| NCBI ENTREZ ACCESS NO | 29995 |
| UNIPROT ACCESS NO | Q9NZU5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene codes for a calcium binding protein significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LMCD1 for Human |
Record No:9
| ACCESS NO | 100239 |
| GENE | LBH |
| DESCRIPTION | Likely ortholog of mouse limb-bud and heart gene |
| NCBI ENTREZ ACCESS NO | 81606 |
| UNIPROT ACCESS NO | Q53QV2 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:10
| ACCESS NO | 100267 |
| GENE | LOXL2 |
| DESCRIPTION | Lysyl oxidase-like 2 |
| NCBI ENTREZ ACCESS NO | 4017 |
| UNIPROT ACCESS NO | Q9Y4K0 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in cross-linking of collagen and elastin. Thus it helps in airway repair and remodelling. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LOXL2 [EPR12733] for Mouse/Rat/Human |
Record No:11
| ACCESS NO | 100287 |
| GENE | Lama3 |
| DESCRIPTION | Laminin alpha-3 chain |
| NCBI ENTREZ ACCESS NO | 16774 |
| UNIPROT ACCESS NO | Q61789 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in cell adhesion and it was found to be downregulated. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-ICAM1 for Rat/Human |
Record No:12
| ACCESS NO | 100307 |
| GENE | Lamb2 |
| DESCRIPTION | Laminin b-2 |
| NCBI ENTREZ ACCESS NO | 25473 |
| UNIPROT ACCESS NO | P15800 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in focal adhesion and ECM receptor interaction and cell communication. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Lamin B2 [LN43] for Mouse/Human |
Record No:13
| ACCESS NO | 100323 |
| GENE | Lmna |
| DESCRIPTION | Lamin a |
| NCBI ENTREZ ACCESS NO | 60374 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It participates in cell communication. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Lamin A [133A2] for Mouse/Rat/Human |
Record No:14
| ACCESS NO | 100325 |
| GENE | LOC100912362 |
| DESCRIPTION | Thymosin beta -4 |
| NCBI ENTREZ ACCESS NO | 100912362 |
| UNIPROT ACCESS NO | F1M967 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It participates in the regulation of actin cytoskeleton. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:15
| ACCESS NO | 100330 |
| GENE | Lsp1 |
| DESCRIPTION | Lymphocyte-specific protein 1 |
| NCBI ENTREZ ACCESS NO | 16985 |
| UNIPROT ACCESS NO | P19973 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced chemicals |
| SAMPLE | Auricular Lymph Nodes |
| TECHNIQUES | 2D DIGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is a negative regulator of neutrophil chemotaxis. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20860378 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LSP1 for Mouse/Rat/Human |
Record No:16
| ACCESS NO | 100346 |
| GENE | LATS2 |
| DESCRIPTION | LATS-large tumour suppressor homologue 2 |
| NCBI ENTREZ ACCESS NO | 26524 |
| UNIPROT ACCESS NO | Q9NRM7 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is upregulated in asthma exacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LATS2 for Rat/Human |
Record No:17
| ACCESS NO | 100359 |
| GENE | LIMK2 |
| DESCRIPTION | LIM domain kinase 2 |
| NCBI ENTREZ ACCESS NO | 3985 |
| UNIPROT ACCESS NO | P53671 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It participates in cellular function and maintainance. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LIM kinase 2 for Mouse/Rat/Human |
Record No:18
| ACCESS NO | 100374 |
| GENE | Lsp1 |
| DESCRIPTION | Lymphocyte specific protein 1 |
| NCBI ENTREZ ACCESS NO | 16985 |
| UNIPROT ACCESS NO | P19973 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Occupational asthma induced by chemicals |
| SAMPLE | Auricular lymph nodes |
| TECHNIQUES | 2D DIGE and MALDI-TOF-MS and western blot |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene is responsible for increased levels of T and B lymphocytes after allergen sensitization. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23038679 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LSP1 for Mouse/Rat/Human |
Record No:19
| ACCESS NO | 100385 |
| GENE | Lcn2 |
| DESCRIPTION | Neutrophil gelatinase-associated lipocalin |
| NCBI ENTREZ ACCESS NO | 16819 |
| UNIPROT ACCESS NO | P11672 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | 2D PAGE andLC-MS/MS followed by western blot and r |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene is expressed and secreted by immune cells. It is well known for its function as a shuttle for iron and siderophores. Elevated tissue NGAL expression has been documented under diverse infectious and inflammatory conditions such as asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20029843 |
| DRUG TARGET | BE0001084 |
| MONCLONAL ANTIBODY | Anti-Lipocalin 2 for Human |
Record No:20
| ACCESS NO | 100399 |
| GENE | LTA |
| DESCRIPTION | Lymphotoxin alpha |
| NCBI ENTREZ ACCESS NO | 4049 |
| UNIPROT ACCESS NO | P01374 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | gDNA from chord blood cells |
| TECHNIQUES | Semiquantitative RT-PCR and Immunoassay (ELISA and |
| OMICS | Genomics and ot |
| STUDY | Low Throughput |
| COMMENTS | B-cell proliferation and IgE synthesis (biomarker of atopic dermatitis). |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 9767423 |
| DRUG TARGET | BE0001087 |
| MONCLONAL ANTIBODY | Anti-TNF beta for Mouse/Human |
Record No:21
| ACCESS NO | 100400 |
| GENE | LTA |
| DESCRIPTION | Lymphotoxin alpha (LT- A) |
| NCBI ENTREZ ACCESS NO | 4049 |
| UNIPROT ACCESS NO | P01374 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | gDNA |
| TECHNIQUES | Genotyping by PCR-RFLP |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This gene along with elevated level of chord blood IgE and maternal stress is responsible for the development of atopic dermatitis in children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21539617 |
| DRUG TARGET | BE0001087 |
| MONCLONAL ANTIBODY | Anti-TNF beta for Mouse/Human |
Record No:22
| ACCESS NO | 100433 |
| GENE | LTF |
| DESCRIPTION | Lactotransferrin |
| NCBI ENTREZ ACCESS NO | 4057 |
| UNIPROT ACCESS NO | P02788 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe asthma |
| SAMPLE | CD4 + T cells |
| TECHNIQUES | Microarray and Real time Q-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is upregulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21917308 |
| DRUG TARGET | BE0000994 |
| MONCLONAL ANTIBODY | Anti-Lactoferrin for Mouse/Rat/Human |
Record No:23
| ACCESS NO | 100436 |
| GENE | LCN2 |
| DESCRIPTION | Lipocalin 2 |
| NCBI ENTREZ ACCESS NO | 3934 |
| UNIPROT ACCESS NO | P80188 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe asthma |
| SAMPLE | CD4 + T cells |
| TECHNIQUES | Microarray and Real time Q-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is upregulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21917308 |
| DRUG TARGET | BE0001084 |
| MONCLONAL ANTIBODY | Anti-Lipocalin 2 for Human |
Record No:24
| ACCESS NO | 100444 |
| GENE | LTF |
| DESCRIPTION | Lactotransferrin |
| NCBI ENTREZ ACCESS NO | 4057 |
| UNIPROT ACCESS NO | P02788 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe asthma |
| SAMPLE | CD8 + T cells |
| TECHNIQUES | Microarray and Real time Q-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is upregulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21917308 |
| DRUG TARGET | BE0000994 |
| MONCLONAL ANTIBODY | Anti-Lactoferrin for Mouse/Rat/Human |
Record No:25
| ACCESS NO | 100447 |
| GENE | LCN2 |
| DESCRIPTION | Lipocalin 2 |
| NCBI ENTREZ ACCESS NO | 3934 |
| UNIPROT ACCESS NO | P80188 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Severe asthma |
| SAMPLE | CD8 + T cells |
| TECHNIQUES | Microarray and Real time Q-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is upregulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21917308 |
| DRUG TARGET | BE0001084 |
| MONCLONAL ANTIBODY | Anti-Lipocalin 2 for Human |
Record No:26
| ACCESS NO | 100475 |
| GENE | LIF |
| DESCRIPTION | Leukemia inhibitory factor |
| NCBI ENTREZ ACCESS NO | 3976 |
| UNIPROT ACCESS NO | P15018 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Airway smooth muscle cell (ASM) line |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is downregulated in ASM after dexamethasone treatment. |
| GEO_PRIDE_ACCESS_NO | GSE3946 |
| REFERENCE | 21257922 |
| DRUG TARGET | BE0000416 |
| MONCLONAL ANTIBODY | Anti-LIF for Mouse/Human |
Record No:27
| ACCESS NO | 100499 |
| GENE | LMNA |
| DESCRIPTION | Lamin A/C |
| NCBI ENTREZ ACCESS NO | 4000 |
| UNIPROT ACCESS NO | P02545 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of glucocorticoid treatment |
| SAMPLE | Bronchial biopsy |
| TECHNIQUES | iTRAQ labelling followed by nano LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in fibrosis. It is downregulated in untreated asthma patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21939520 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Lamin A for Mouse/Rat/Human |
Record No:28
| ACCESS NO | 100677 |
| GENE | Lcp1 |
| DESCRIPTION | Lymphocyte cytosolic protein 1 |
| NCBI ENTREZ ACCESS NO | 18826 |
| UNIPROT ACCESS NO | Q61233 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergen induced asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Plastin L for Human |
Record No:29
| ACCESS NO | 100704 |
| GENE | Lcn2 |
| DESCRIPTION | Lipocalin 2 |
| NCBI ENTREZ ACCESS NO | 16819 |
| UNIPROT ACCESS NO | P11672 |
| ORGANISM | TSLP TG mice and BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid Broncho Alveol |
| TECHNIQUES | LC-MS/MS and Western blot and qRT PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Significantly lowered after Dexamethasone treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22837640 |
| DRUG TARGET | BE0001084 |
| MONCLONAL ANTIBODY | Anti-Lipocalin 2 for Human |
Record No:30
| ACCESS NO | 100743 |
| GENE | LMAN1 |
| DESCRIPTION | Lectin mannose-binding 1 |
| NCBI ENTREZ ACCESS NO | 3998 |
| UNIPROT ACCESS NO | P49257 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Perpheral blood mononuclear cells |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Reduced expression in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21966607 |
| DRUG TARGET | BE0002119 |
| MONCLONAL ANTIBODY | Anti-LMAN1 for Mouse/Rat/Human |
Record No:31
| ACCESS NO | 100941 |
| GENE | Lgals4 |
| DESCRIPTION | Lectin galactose binding soluble 4 |
| NCBI ENTREZ ACCESS NO | 16855 |
| UNIPROT ACCESS NO | Q8K419 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after induction with food allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GAL4 for Human |
Record No:32
| ACCESS NO | 101054 |
| GENE | LAMP1 |
| DESCRIPTION | Lysosome-associated membrane glycoprotein 1 |
| NCBI ENTREZ ACCESS NO | 3916 |
| UNIPROT ACCESS NO | P11279 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly down regulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LAMP1 [H4A3] for Rat/Human |
Record No:33
| ACCESS NO | 101082 |
| GENE | LCN2 (NGAL) |
| DESCRIPTION | Gelatinase-associated lipocalin |
| NCBI ENTREZ ACCESS NO | 3934 |
| UNIPROT ACCESS NO | P80188 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma-COPD overlap |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Only sputum NGAL is significantly elevated in COPD-asthma overlap compared with COPD (p=0.00016) and could be used to differentiate patients with overlap from those with COPD. Increased induced sputum levels of NGAL is a characteristic feature of overlap suggesting enhanced neutrophilic airway inflammation and/or airway epithelial injury in COPD-asthma overlap. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23794464 |
| DRUG TARGET | BE0001084 |
| MONCLONAL ANTIBODY | Anti-Lipocalin 2 for Human |
Record No:34
| ACCESS NO | 101194 |
| GENE | LEP |
| DESCRIPTION | leptin |
| NCBI ENTREZ ACCESS NO | 3952 |
| UNIPROT ACCESS NO | P41159 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and obesity |
| SAMPLE | Serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | The higher leptin levels was correlated with severe asthma. CRP concentrations reduced after 1 year of interdisciplinary treatment from 59 to 33. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22170805 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:35
| ACCESS NO | 101210 |
| GENE | LAMB3 |
| DESCRIPTION | Laminin subunit beta-3 |
| NCBI ENTREZ ACCESS NO | 3914 |
| UNIPROT ACCESS NO | Q13751 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LAMB3 for Mouse/Rat/Human |
Record No:36
| ACCESS NO | 101211 |
| GENE | LDHC |
| DESCRIPTION | L-lactate dehydrogenase C chain |
| NCBI ENTREZ ACCESS NO | 3948 |
| UNIPROT ACCESS NO | P07864 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be upregulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | BE0000149 |
| MONCLONAL ANTIBODY | Anti-Lactate Dehydrogenase C for Human |
Record No:37
| ACCESS NO | 101268 |
| GENE | LEP |
| DESCRIPTION | leptin |
| NCBI ENTREZ ACCESS NO | 3952 |
| UNIPROT ACCESS NO | P41159 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and obesity |
| SAMPLE | Broncho Alveolar Lavage (BAL) and plasma |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Obesity was associated with higher BAL and plasma leptin levels in asthmatics and controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21332421 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:38
| ACCESS NO | 101269 |
| GENE | LYZ |
| DESCRIPTION | Lysozyme |
| NCBI ENTREZ ACCESS NO | 4069 |
| UNIPROT ACCESS NO | P61626 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Present in exhaled blood condensate of asthma patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21105917 |
| DRUG TARGET | BE0003751 |
| MONCLONAL ANTIBODY | N/A |
Record No:39
| ACCESS NO | 101298 |
| GENE | LTF |
| DESCRIPTION | Lactoferrin |
| NCBI ENTREZ ACCESS NO | 4057 |
| UNIPROT ACCESS NO | P02788 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic Rhinitis |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | MALDI Tof/Tof and ELISA |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Decreased in sera(through ELISA) but increased in nasal lavage fluid(through proteomics). |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20015277 |
| DRUG TARGET | BE0000994 |
| MONCLONAL ANTIBODY | Anti-Lactoferrin for Mouse/Rat/Human |
Record No:40
| ACCESS NO | 101301 |
| GENE | Ldh |
| DESCRIPTION | L-lactate dehydrogenase |
| NCBI ENTREZ ACCESS NO | 24533 |
| UNIPROT ACCESS NO | P04642 |
| ORGANISM | Male Sprague–Dawley rats |
| DISEASE PHENOTYPE | Asthma(Effect of vasoactive peptide in OVA challenged rats) |
| SAMPLE | Broncho alveolar lavage fluid |
| TECHNIQUES | Biochemical tests |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased after OVA challenge but decreased on administering Vasoactive Intestinal Peptide. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19808073 |
| DRUG TARGET | BE0001324 |
| MONCLONAL ANTIBODY | N/A |
Record No:41
| ACCESS NO | 101315 |
| GENE | LASP-1 |
| DESCRIPTION | LIM and SH3 protein 1 |
| NCBI ENTREZ ACCESS NO | 3927 |
| UNIPROT ACCESS NO | Q14847 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy(Comparison of Dendritic cell proteome in atopic and non atopic patients) |
| SAMPLE | Dendritic cell |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in regulation of actin based cytoskeletal activities. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19494521 |
| DRUG TARGET | BE0004759 |
| MONCLONAL ANTIBODY | Anti-LASP1 for Mouse/Rat/Human |
Record No:42
| ACCESS NO | 101348 |
| GENE | LXRalpha/Nr1h3 |
| DESCRIPTION | Liver X receptor alpha/Beta |
| NCBI ENTREZ ACCESS NO | 58852 |
| UNIPROT ACCESS NO | Q5I035 |
| ORGANISM | Male Brown Norway rats |
| DISEASE PHENOTYPE | Asthma (LXR agonist treated rat) |
| SAMPLE | Tracheal tissue |
| TECHNIQUES | RT-PCR/ELISA |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | LXR controls transcription of genes in cholesterol efflux pathway. Increases airway reactivity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18768884 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:43
| ACCESS NO | 101352 |
| GENE | Lcp1 |
| DESCRIPTION | Lymphocyte cytosolic protein 1 |
| NCBI ENTREZ ACCESS NO | 18826 |
| UNIPROT ACCESS NO | Q61233 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in cell migration and adhesion. Significantly upregulated by 2 fold. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Plastin L Mouse/ Rat/ Human |
Record No:44
| ACCESS NO | 101443 |
| GENE | Lcn2 |
| DESCRIPTION | Lipocalin 2 |
| NCBI ENTREZ ACCESS NO | 16819 |
| UNIPROT ACCESS NO | P11672 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3hours and 12 hours of fungal allergen induction in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0001084 |
| MONCLONAL ANTIBODY | Anti-Lipocalin 2 for Human |
Record No:45
| ACCESS NO | 101463 |
| GENE | Lilrb4 |
| DESCRIPTION | Leukocyte immunoglobulin-like receptor subfamily B member 4 |
| NCBI ENTREZ ACCESS NO | 14728 |
| UNIPROT ACCESS NO | Q64281 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY |
Record No:46
| ACCESS NO | 101473 |
| GENE | Lcp2 |
| DESCRIPTION | Lymphocyte cytosolic protein 2 |
| NCBI ENTREZ ACCESS NO | 16822 |
| UNIPROT ACCESS NO | Q60787 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-SLP76 for Mouse/Rat/Human |
Record No:47
| ACCESS NO | 101475 |
| GENE | Ltb |
| DESCRIPTION | Lymphotoxin B |
| NCBI ENTREZ ACCESS NO | 16994 |
| UNIPROT ACCESS NO | P41155 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of fungal allergen challenge in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Lymphotoxin Beta for Human |
Record No:48
| ACCESS NO | 101489 |
| GENE | Lif |
| DESCRIPTION | Leukemia inhibitory factor |
| NCBI ENTREZ ACCESS NO | 16878 |
| UNIPROT ACCESS NO | P09056 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LIF for Human |
Record No:49
| ACCESS NO | 101507 |
| GENE | Lmnb1 |
| DESCRIPTION | Lamin B1 |
| NCBI ENTREZ ACCESS NO | 16906 |
| UNIPROT ACCESS NO | P14733 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Lamin B1 for Mouse/Rat/Human |
Record No:50
| ACCESS NO | 101521 |
| GENE | Litaf |
| DESCRIPTION | LPS-induced TN factor |
| NCBI ENTREZ ACCESS NO | 56722 |
| UNIPROT ACCESS NO | Q9JLJ0 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LITAF for Human |
Record No:51
| ACCESS NO | 101527 |
| GENE | LEP |
| DESCRIPTION | Leptin |
| NCBI ENTREZ ACCESS NO | 3952 |
| UNIPROT ACCESS NO | P41159 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma rhinoconjunctivitis and eczema |
| SAMPLE | EDTA added blood plasma |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | High leptin were associated with increased persistence of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18331416 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:52
| ACCESS NO | 101658 |
| GENE | Lgals1 |
| DESCRIPTION | Beta galactoside binding protein |
| NCBI ENTREZ ACCESS NO | 16852 |
| UNIPROT ACCESS NO | P16045 |
| ORGANISM | Male BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | 2D electrophoresis and MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16100447 |
| DRUG TARGET | BE0004493 |
| MONCLONAL ANTIBODY | Anti-Galectin 1 for Mouse/Rat/Human |
Record No:53
| ACCESS NO | 101705 |
| GENE | LCN2 |
| DESCRIPTION | Neutrophil gelatinase-associated lipocalin (NGAL) |
| NCBI ENTREZ ACCESS NO | 3934 |
| UNIPROT ACCESS NO | P80188 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This neutrophilic granule protein is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0001084 |
| MONCLONAL ANTIBODY | Anti-Lambda Light chain [LcN-2] for Human |
Record No:54
| ACCESS NO | 101737 |
| GENE | LDHB |
| DESCRIPTION | L-Lactate dehydrogenase B chain |
| NCBI ENTREZ ACCESS NO | 3945 |
| UNIPROT ACCESS NO | F5H793 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000068 |
| MONCLONAL ANTIBODY | Anti-Lactate Dehydrogenase B [60H11] for Mouse/Rat/Human |
Record No:55
| ACCESS NO | 101764 |
| GENE | LBP |
| DESCRIPTION | dJ564F22.1 (lipopolysaccharide-binding protein) |
| NCBI ENTREZ ACCESS NO | 3929 |
| UNIPROT ACCESS NO | P18428 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This local matrix protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LBP [EPR10865] for Human |
Record No:56
| ACCESS NO | 101792 |
| GENE | LTF |
| DESCRIPTION | Lactoferrin |
| NCBI ENTREZ ACCESS NO | 4057 |
| UNIPROT ACCESS NO | E7ER44 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This serum protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000994 |
| MONCLONAL ANTIBODY | Anti-Lactoferrin [2B8] for Mouse/Rat/Human |
Record No:57
| ACCESS NO | 101803 |
| GENE | LRG1 |
| DESCRIPTION | Leucine-rich #-2-glycoprotein |
| NCBI ENTREZ ACCESS NO | 116844 |
| UNIPROT ACCESS NO | P02750 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This cytoskeletal protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LRG1 [EPR12362] for Mouse/Rat/Human |
Record No:58
| ACCESS NO | 101849 |
| GENE | LILRB2 |
| DESCRIPTION | Immunoglobulin-like receptor subfamily B |
| NCBI ENTREZ ACCESS NO | 10288 |
| UNIPROT ACCESS NO | Q8N423 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic Rhinitis induced by pollen allergen |
| SAMPLE | Nasal lavage fluids |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This anti inflammatory gene showed higher expression levels in patients than in controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15836756 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:59
| ACCESS NO | 101924 |
| GENE | LAMA5 |
| DESCRIPTION | Laminin a-5 chain precursor |
| NCBI ENTREZ ACCESS NO | 3911 |
| UNIPROT ACCESS NO | O15230 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Laminin alpha 5 for Human |
Record No:60
| ACCESS NO | 101943 |
| GENE | LATS2 |
| DESCRIPTION | LATS large tumour suppressor homologue 2 |
| NCBI ENTREZ ACCESS NO | 26524 |
| UNIPROT ACCESS NO | Q9NRM7 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthma. Involved in immune and lymphatic system development. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LATS2 for Rat/Human |
Record No:61
| ACCESS NO | 101964 |
| GENE | LIMK2 |
| DESCRIPTION | LIM domain kinase 2 |
| NCBI ENTREZ ACCESS NO | 3985 |
| UNIPROT ACCESS NO | P53671 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthmatic children. Involved in cellular function and maintenance. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LIM kinase 2 for Mouse/Rat/Human |
Record No:62
| ACCESS NO | 101973 |
| GENE | LAMA3 |
| DESCRIPTION | Laminin alpha 3 |
| NCBI ENTREZ ACCESS NO | 3909 |
| UNIPROT ACCESS NO | Q16787 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Expressed in patients with allergic rhinitis with or without asthma in upper airways. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:63
| ACCESS NO | 101986 |
| GENE | LAMP2 |
| DESCRIPTION | Lysosomal-associated membrane protein 2 |
| NCBI ENTREZ ACCESS NO | 3920 |
| UNIPROT ACCESS NO | P13473 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in patients with allergic rhinitis with or without asthma in the upper airways. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LAMP2 for Mouse/Rabbit/Human |
Record No:64
| ACCESS NO | 102077 |
| GENE | LIF |
| DESCRIPTION | Leukemia inhibitory factor |
| NCBI ENTREZ ACCESS NO | 3976 |
| UNIPROT ACCESS NO | P15018 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in inflammation and immunoregulation. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LIF for Mouse/Human |
Record No:65
| ACCESS NO | 102105 |
| GENE | LCP2 |
| DESCRIPTION | Lymphocyte cytosolic protein 2 |
| NCBI ENTREZ ACCESS NO | 3937 |
| UNIPROT ACCESS NO | Q13094 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in TCR pathway and induces IL4. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-SLP76 for Mouse/Rat/Human |
Record No:66
| ACCESS NO | 102148 |
| GENE | LGALS7 |
| DESCRIPTION | Lectin galactoside-binding soluble-7 |
| NCBI ENTREZ ACCESS NO | 3963 |
| UNIPROT ACCESS NO | P47929 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Bronchial Biopsy |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | GSE41649 |
| REFERENCE | 19842841 |
| DRUG TARGET | BE0001008 |
| MONCLONAL ANTIBODY | Anti-Galectin for Human |