BROWSE RESULT OF L

66 Records

 

Record No:1


ACCESS NO100011
GENELPGAT1
DESCRIPTIONLysophosphatidylglycerol acyltransferase 1
NCBI ENTREZ ACCESS NO9926
UNIPROT ACCESS NOQ92604
ORGANISMHuman
DISEASE PHENOTYPEAsthma ( comparison between high and low socio-economic conditions [SEC])
SAMPLECD2+ cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene is upregulated more in low SEC group.
GEO_PRIDE_ACCESS_NOGSE7894
REFERENCE19001005
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:2


ACCESS NO100031
GENELONPL
DESCRIPTIONLon peptidase 2
NCBI ENTREZ ACCESS NO83752
UNIPROT ACCESS NOQ86WA8
ORGANISMHuman
DISEASE PHENOTYPEAsthma ( comparison between high and low socio-economic conditions [SEC])
SAMPLECD2+ cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene is upregulated more in high SEC group.
GEO_PRIDE_ACCESS_NOGSE7894
REFERENCE19001005
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:3


ACCESS NO100052
GENELTB4R
DESCRIPTIONLeukotriene B4 receptor
NCBI ENTREZ ACCESS NO1241
UNIPROT ACCESS NOQ15722
ORGANISMHuman
DISEASE PHENOTYPEAcute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESMicroarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is involved in arachidonic acid/prostagandin metabolism.
GEO_PRIDE_ACCESS_NOGSE16032
REFERENCE19620293
DRUG TARGET
MONCLONAL ANTIBODYAnti-Leukotriene B4 Receptor for Human


Record No:4


ACCESS NO100124
GENELilrb4
DESCRIPTIONLeukocyte immunoglobulin-like receptor subfamily B (member 4)
NCBI ENTREZ ACCESS NO14728
UNIPROT ACCESS NOQ64281
ORGANISMMouse
DISEASE PHENOTYPEAllergic asthma and the role of IL-4 and IL-13
SAMPLELung tissue
TECHNIQUESDNA Affymetrix microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is an IL-4 specific immunoglobulin fragment gene induced in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19249085
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:5


ACCESS NO100131
GENELilrb4
DESCRIPTIONLeukocyte immunoglobulin-like receptor (subfamily B) member 4
NCBI ENTREZ ACCESS NO14728
UNIPROT ACCESS NOQ64281
ORGANISMMouse
DISEASE PHENOTYPEAllergic asthma and the role of IL-4 and IL-13
SAMPLELung tissue
TECHNIQUESDNA Affymetrix microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is an IL-4 specific host immune responsive gene induced in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19249085
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:6


ACCESS NO100153
GENELOXL2
DESCRIPTIONLysyl oxidase-like 2
NCBI ENTREZ ACCESS NO4017
UNIPROT ACCESS NOQ9Y4K0
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is a cell communication protein significantly upregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYAnti-LOXL2 [EPR12733] for Mouse/Rat/Human


Record No:7


ACCESS NO100168
GENELTB
DESCRIPTIONLymphotoxin beta
NCBI ENTREZ ACCESS NO4050
UNIPROT ACCESS NOQ06643
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is a cell communication protein significantly upregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:8


ACCESS NO100223
GENELMCD1
DESCRIPTIONLIM and cysteine-rich domains 1
NCBI ENTREZ ACCESS NO29995
UNIPROT ACCESS NOQ9NZU5
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene codes for a calcium binding protein significantly down regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYAnti-LMCD1 for Human


Record No:9


ACCESS NO100239
GENELBH
DESCRIPTIONLikely ortholog of mouse limb-bud and heart gene
NCBI ENTREZ ACCESS NO81606
UNIPROT ACCESS NOQ53QV2
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis gene is significantly down regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:10


ACCESS NO100267
GENELOXL2
DESCRIPTIONLysyl oxidase-like 2
NCBI ENTREZ ACCESS NO4017
UNIPROT ACCESS NOQ9Y4K0
ORGANISMHuman
DISEASE PHENOTYPEAsthma exacerbation after rhinovirus infection
SAMPLEPrimary bronchial epithelial cells
TECHNIQUESAffymetrix GeneChip Microarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is involved in cross-linking of collagen and elastin. Thus it helps in airway repair and remodelling.
GEO_PRIDE_ACCESS_NOGSE13396
REFERENCE19710636
DRUG TARGET
MONCLONAL ANTIBODYAnti-LOXL2 [EPR12733] for Mouse/Rat/Human


Record No:11


ACCESS NO100287
GENELama3
DESCRIPTIONLaminin alpha-3 chain
NCBI ENTREZ ACCESS NO16774
UNIPROT ACCESS NOQ61789
ORGANISMMouse
DISEASE PHENOTYPEAsthma induced by Aspergillus fumigatus allergens
SAMPLEPeripheral blood monocytes
TECHNIQUESDNA Microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis protein is involved in cell adhesion and it was found to be downregulated.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20840155
DRUG TARGET
MONCLONAL ANTIBODYAnti-ICAM1 for Rat/Human


Record No:12


ACCESS NO100307
GENELamb2
DESCRIPTIONLaminin b-2
NCBI ENTREZ ACCESS NO25473
UNIPROT ACCESS NOP15800
ORGANISMRat
DISEASE PHENOTYPEEarly airway response (EAR) phase of asthma
SAMPLELung tissue
TECHNIQUESSerial analysis of gene expression (SAGE)
OMICSGenomics
STUDY High Throughput
COMMENTSThis protein is involved in focal adhesion and ECM receptor interaction and cell communication.
GEO_PRIDE_ACCESS_NOGSE2475
REFERENCE18922145
DRUG TARGET
MONCLONAL ANTIBODYAnti-Lamin B2 [LN43] for Mouse/Human


Record No:13


ACCESS NO100323
GENELmna
DESCRIPTIONLamin a
NCBI ENTREZ ACCESS NO60374
UNIPROT ACCESS NON/A
ORGANISMRat
DISEASE PHENOTYPEEarly airway response (EAR) phase of asthma
SAMPLELung tissue
TECHNIQUESSerial analysis of gene expression (SAGE)
OMICSGenomics
STUDY High Throughput
COMMENTSIt participates in cell communication.
GEO_PRIDE_ACCESS_NOGSE2475
REFERENCE18922145
DRUG TARGET
MONCLONAL ANTIBODYAnti-Lamin A [133A2] for Mouse/Rat/Human


Record No:14


ACCESS NO100325
GENELOC100912362
DESCRIPTIONThymosin beta -4
NCBI ENTREZ ACCESS NO100912362
UNIPROT ACCESS NOF1M967
ORGANISMRat
DISEASE PHENOTYPEEarly airway response (EAR) phase of asthma
SAMPLELung tissue
TECHNIQUESSerial analysis of gene expression (SAGE)
OMICSGenomics
STUDY High Throughput
COMMENTSIt participates in the regulation of actin cytoskeleton.
GEO_PRIDE_ACCESS_NOGSE2475
REFERENCE18922145
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:15


ACCESS NO100330
GENELsp1
DESCRIPTIONLymphocyte-specific protein 1
NCBI ENTREZ ACCESS NO16985
UNIPROT ACCESS NOP19973
ORGANISMMouse
DISEASE PHENOTYPEAsthma induced chemicals
SAMPLEAuricular Lymph Nodes
TECHNIQUES2D DIGE and MALDI-TOF-MS
OMICSProteomics
STUDY High Throughput
COMMENTSIt is a negative regulator of neutrophil chemotaxis.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20860378
DRUG TARGET
MONCLONAL ANTIBODYAnti-LSP1 for Mouse/Rat/Human


Record No:16


ACCESS NO100346
GENELATS2
DESCRIPTIONLATS-large tumour suppressor homologue 2
NCBI ENTREZ ACCESS NO26524
UNIPROT ACCESS NOQ9NRM7
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESIllumina Human Ref8 BeadChip arrays
OMICSGenomics
STUDY High Throughput
COMMENTSIt is upregulated in asthma exacerbation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19187333
DRUG TARGET
MONCLONAL ANTIBODYAnti-LATS2 for Rat/Human


Record No:17


ACCESS NO100359
GENELIMK2
DESCRIPTIONLIM domain kinase 2
NCBI ENTREZ ACCESS NO3985
UNIPROT ACCESS NOP53671
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESIllumina Human Ref8 BeadChip arrays
OMICSGenomics
STUDY High Throughput
COMMENTSIt participates in cellular function and maintainance.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19187333
DRUG TARGET
MONCLONAL ANTIBODYAnti-LIM kinase 2 for Mouse/Rat/Human


Record No:18


ACCESS NO100374
GENELsp1
DESCRIPTIONLymphocyte specific protein 1
NCBI ENTREZ ACCESS NO16985
UNIPROT ACCESS NOP19973
ORGANISMMouse
DISEASE PHENOTYPEOccupational asthma induced by chemicals
SAMPLEAuricular lymph nodes
TECHNIQUES2D DIGE and MALDI-TOF-MS and western blot
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSThis gene is responsible for increased levels of T and B lymphocytes after allergen sensitization.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23038679
DRUG TARGET
MONCLONAL ANTIBODYAnti-LSP1 for Mouse/Rat/Human


Record No:19


ACCESS NO100385
GENELcn2
DESCRIPTIONNeutrophil gelatinase-associated lipocalin
NCBI ENTREZ ACCESS NO16819
UNIPROT ACCESS NOP11672
ORGANISMMouse
DISEASE PHENOTYPEAsthma exacerbation and role of ambient particulate matter
SAMPLEBroncho Alveolar Lavage (BAL)F
TECHNIQUES2D PAGE andLC-MS/MS followed by western blot and r
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSThis gene is expressed and secreted by immune cells. It is well known for its function as a shuttle for iron and siderophores. Elevated tissue NGAL expression has been documented under diverse infectious and inflammatory conditions such as asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20029843
DRUG TARGETBE0001084
MONCLONAL ANTIBODYAnti-Lipocalin 2 for Human


Record No:20


ACCESS NO100399
GENELTA
DESCRIPTIONLymphotoxin alpha
NCBI ENTREZ ACCESS NO4049
UNIPROT ACCESS NOP01374
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEgDNA from chord blood cells
TECHNIQUESSemiquantitative RT-PCR and Immunoassay (ELISA and
OMICSGenomics and ot
STUDY Low Throughput
COMMENTSB-cell proliferation and IgE synthesis (biomarker of atopic dermatitis).
GEO_PRIDE_ACCESS_NON/A
REFERENCE9767423
DRUG TARGETBE0001087
MONCLONAL ANTIBODYAnti-TNF beta for Mouse/Human


Record No:21


ACCESS NO100400
GENELTA
DESCRIPTIONLymphotoxin alpha (LT- A)
NCBI ENTREZ ACCESS NO4049
UNIPROT ACCESS NOP01374
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEgDNA
TECHNIQUESGenotyping by PCR-RFLP
OMICSGenomics
STUDY Low Throughput
COMMENTSThis gene along with elevated level of chord blood IgE and maternal stress is responsible for the development of atopic dermatitis in children.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21539617
DRUG TARGETBE0001087
MONCLONAL ANTIBODYAnti-TNF beta for Mouse/Human


Record No:22


ACCESS NO100433
GENELTF
DESCRIPTIONLactotransferrin
NCBI ENTREZ ACCESS NO4057
UNIPROT ACCESS NOP02788
ORGANISMHuman
DISEASE PHENOTYPESevere asthma
SAMPLECD4 + T cells
TECHNIQUESMicroarray and Real time Q-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is upregulated in asthma inflammation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21917308
DRUG TARGETBE0000994
MONCLONAL ANTIBODYAnti-Lactoferrin for Mouse/Rat/Human


Record No:23


ACCESS NO100436
GENELCN2
DESCRIPTIONLipocalin 2
NCBI ENTREZ ACCESS NO3934
UNIPROT ACCESS NOP80188
ORGANISMHuman
DISEASE PHENOTYPESevere asthma
SAMPLECD4 + T cells
TECHNIQUESMicroarray and Real time Q-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is upregulated in asthma inflammation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21917308
DRUG TARGETBE0001084
MONCLONAL ANTIBODYAnti-Lipocalin 2 for Human


Record No:24


ACCESS NO100444
GENELTF
DESCRIPTIONLactotransferrin
NCBI ENTREZ ACCESS NO4057
UNIPROT ACCESS NOP02788
ORGANISMHuman
DISEASE PHENOTYPESevere asthma
SAMPLECD8 + T cells
TECHNIQUESMicroarray and Real time Q-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is upregulated in asthma inflammation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21917308
DRUG TARGETBE0000994
MONCLONAL ANTIBODYAnti-Lactoferrin for Mouse/Rat/Human


Record No:25


ACCESS NO100447
GENELCN2
DESCRIPTIONLipocalin 2
NCBI ENTREZ ACCESS NO3934
UNIPROT ACCESS NOP80188
ORGANISMHuman
DISEASE PHENOTYPESevere asthma
SAMPLECD8 + T cells
TECHNIQUESMicroarray and Real time Q-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is upregulated in asthma inflammation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21917308
DRUG TARGETBE0001084
MONCLONAL ANTIBODYAnti-Lipocalin 2 for Human


Record No:26


ACCESS NO100475
GENELIF
DESCRIPTIONLeukemia inhibitory factor
NCBI ENTREZ ACCESS NO3976
UNIPROT ACCESS NOP15018
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEAirway smooth muscle cell (ASM) line
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is downregulated in ASM after dexamethasone treatment.
GEO_PRIDE_ACCESS_NOGSE3946
REFERENCE21257922
DRUG TARGETBE0000416
MONCLONAL ANTIBODYAnti-LIF for Mouse/Human


Record No:27


ACCESS NO100499
GENELMNA
DESCRIPTIONLamin A/C
NCBI ENTREZ ACCESS NO4000
UNIPROT ACCESS NOP02545
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of glucocorticoid treatment
SAMPLEBronchial biopsy
TECHNIQUESiTRAQ labelling followed by nano LC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is involved in fibrosis. It is downregulated in untreated asthma patients.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21939520
DRUG TARGET
MONCLONAL ANTIBODYAnti-Lamin A for Mouse/Rat/Human


Record No:28


ACCESS NO100677
GENELcp1
DESCRIPTIONLymphocyte cytosolic protein 1
NCBI ENTREZ ACCESS NO18826
UNIPROT ACCESS NOQ61233
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAsthma induced by Ovalbumin
SAMPLELung tissue
TECHNIQUESMALDI Tof
OMICSProteomics
STUDY High Throughput
COMMENTSUpregulated in allergen induced asthma model.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21751807
DRUG TARGET
MONCLONAL ANTIBODYAnti-Plastin L for Human


Record No:29


ACCESS NO100704
GENELcn2
DESCRIPTIONLipocalin 2
NCBI ENTREZ ACCESS NO16819
UNIPROT ACCESS NOP11672
ORGANISMTSLP TG mice and BALB/c Mouse
DISEASE PHENOTYPEAcute and chronic asthma
SAMPLEBroncho Alveolar Lavage (BAL) fluid Broncho Alveol
TECHNIQUESLC-MS/MS and Western blot and qRT PCR
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSSignificantly lowered after Dexamethasone treatment.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22837640
DRUG TARGETBE0001084
MONCLONAL ANTIBODYAnti-Lipocalin 2 for Human


Record No:30


ACCESS NO100743
GENELMAN1
DESCRIPTIONLectin mannose-binding 1
NCBI ENTREZ ACCESS NO3998
UNIPROT ACCESS NOP49257
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEPerpheral blood mononuclear cells
TECHNIQUESMicroarray (agilent)
OMICSGenomics
STUDY High Throughput
COMMENTSReduced expression in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21966607
DRUG TARGETBE0002119
MONCLONAL ANTIBODYAnti-LMAN1 for Mouse/Rat/Human


Record No:31


ACCESS NO100941
GENELgals4
DESCRIPTIONLectin galactose binding soluble 4
NCBI ENTREZ ACCESS NO16855
UNIPROT ACCESS NOQ8K419
ORGANISMBALB/C mice
DISEASE PHENOTYPEFood allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin
SAMPLEMesenteric lymph node
TECHNIQUEScDNA microarray
OMICSGenomics
STUDY High Throughput
COMMENTSDownregulated after induction with food allergen challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21211037
DRUG TARGET
MONCLONAL ANTIBODYAnti-GAL4 for Human


Record No:32


ACCESS NO101054
GENELAMP1
DESCRIPTIONLysosome-associated membrane glycoprotein 1
NCBI ENTREZ ACCESS NO3916
UNIPROT ACCESS NOP11279
ORGANISMHuman
DISEASE PHENOTYPEAtopic eczema (AE)
SAMPLEVernix
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is strongly down regulated in atopic eczema.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24205894
DRUG TARGET
MONCLONAL ANTIBODYAnti-LAMP1 [H4A3] for Rat/Human


Record No:33


ACCESS NO101082
GENELCN2 (NGAL)
DESCRIPTIONGelatinase-associated lipocalin
NCBI ENTREZ ACCESS NO3934
UNIPROT ACCESS NOP80188
ORGANISMHuman
DISEASE PHENOTYPEAsthma-COPD overlap
SAMPLESputum
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSOnly sputum NGAL is significantly elevated in COPD-asthma overlap compared with COPD (p=0.00016) and could be used to differentiate patients with overlap from those with COPD. Increased induced sputum levels of NGAL is a characteristic feature of overlap suggesting enhanced neutrophilic airway inflammation and/or airway epithelial injury in COPD-asthma overlap.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23794464
DRUG TARGETBE0001084
MONCLONAL ANTIBODYAnti-Lipocalin 2 for Human


Record No:34


ACCESS NO101194
GENELEP
DESCRIPTIONleptin
NCBI ENTREZ ACCESS NO3952
UNIPROT ACCESS NOP41159
ORGANISMHuman
DISEASE PHENOTYPEAsthma and obesity
SAMPLESerum
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSThe higher leptin levels was correlated with severe asthma. CRP concentrations reduced after 1 year of interdisciplinary treatment from 59 to 33.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22170805
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:35


ACCESS NO101210
GENELAMB3
DESCRIPTIONLaminin subunit beta-3
NCBI ENTREZ ACCESS NO3914
UNIPROT ACCESS NOQ13751
ORGANISMHuman
DISEASE PHENOTYPEFood allergy
SAMPLEPeripheral blood mononuclear cells
TECHNIQUES2D-DIGE and MALDI-TOF/TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein was found to be down regulated in RAST+ subjects with severe food allergies.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22091390
DRUG TARGET
MONCLONAL ANTIBODYAnti-LAMB3 for Mouse/Rat/Human


Record No:36


ACCESS NO101211
GENELDHC
DESCRIPTIONL-lactate dehydrogenase C chain
NCBI ENTREZ ACCESS NO3948
UNIPROT ACCESS NOP07864
ORGANISMHuman
DISEASE PHENOTYPEFood allergy
SAMPLEPeripheral blood mononuclear cells
TECHNIQUES2D-DIGE and MALDI-TOF/TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein was found to be upregulated in RAST+ subjects with severe food allergies.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22091390
DRUG TARGETBE0000149
MONCLONAL ANTIBODYAnti-Lactate Dehydrogenase C for Human


Record No:37


ACCESS NO101268
GENELEP
DESCRIPTIONleptin
NCBI ENTREZ ACCESS NO3952
UNIPROT ACCESS NOP41159
ORGANISMHuman
DISEASE PHENOTYPEAsthma and obesity
SAMPLEBroncho Alveolar Lavage (BAL) and plasma
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSObesity was associated with higher BAL and plasma leptin levels in asthmatics and controls.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21332421
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:38


ACCESS NO101269
GENELYZ
DESCRIPTIONLysozyme
NCBI ENTREZ ACCESS NO4069
UNIPROT ACCESS NOP61626
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEExhaled Breath condensate
TECHNIQUESMALDI Tof/Tof
OMICSProteomics
STUDY High Throughput
COMMENTSPresent in exhaled blood condensate of asthma patients.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21105917
DRUG TARGETBE0003751
MONCLONAL ANTIBODYN/A


Record No:39


ACCESS NO101298
GENELTF
DESCRIPTIONLactoferrin
NCBI ENTREZ ACCESS NO4057
UNIPROT ACCESS NOP02788
ORGANISMHuman
DISEASE PHENOTYPEAllergic Rhinitis
SAMPLENasal lavage fluid
TECHNIQUESMALDI Tof/Tof and ELISA
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSDecreased in sera(through ELISA) but increased in nasal lavage fluid(through proteomics).
GEO_PRIDE_ACCESS_NON/A
REFERENCE20015277
DRUG TARGETBE0000994
MONCLONAL ANTIBODYAnti-Lactoferrin for Mouse/Rat/Human


Record No:40


ACCESS NO101301
GENELdh
DESCRIPTIONL-lactate dehydrogenase
NCBI ENTREZ ACCESS NO24533
UNIPROT ACCESS NOP04642
ORGANISMMale Sprague–Dawley rats
DISEASE PHENOTYPEAsthma(Effect of vasoactive peptide in OVA challenged rats)
SAMPLEBroncho alveolar lavage fluid
TECHNIQUESBiochemical tests
OMICSOthers
STUDY Low Throughput
COMMENTSIncreased after OVA challenge but decreased on administering Vasoactive Intestinal Peptide.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19808073
DRUG TARGETBE0001324
MONCLONAL ANTIBODYN/A


Record No:41


ACCESS NO101315
GENELASP-1
DESCRIPTIONLIM and SH3 protein 1
NCBI ENTREZ ACCESS NO3927
UNIPROT ACCESS NOQ14847
ORGANISMHuman
DISEASE PHENOTYPEAllergy(Comparison of Dendritic cell proteome in atopic and non atopic patients)
SAMPLEDendritic cell
TECHNIQUESMALDI Tof/Tof
OMICSProteomics
STUDY High Throughput
COMMENTSInvolved in regulation of actin based cytoskeletal activities.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19494521
DRUG TARGETBE0004759
MONCLONAL ANTIBODYAnti-LASP1 for Mouse/Rat/Human


Record No:42


ACCESS NO101348
GENELXRalpha/Nr1h3
DESCRIPTIONLiver X receptor alpha/Beta
NCBI ENTREZ ACCESS NO58852
UNIPROT ACCESS NOQ5I035
ORGANISMMale Brown Norway rats
DISEASE PHENOTYPEAsthma (LXR agonist treated rat)
SAMPLETracheal tissue
TECHNIQUESRT-PCR/ELISA
OMICSGenomics
STUDY Low Throughput
COMMENTSLXR controls transcription of genes in cholesterol efflux pathway. Increases airway reactivity.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18768884
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:43


ACCESS NO101352
GENELcp1
DESCRIPTIONLymphocyte cytosolic protein 1
NCBI ENTREZ ACCESS NO18826
UNIPROT ACCESS NOQ61233
ORGANISMMouse
DISEASE PHENOTYPEChronic Asthma
SAMPLELung Tissue and Broncho Alveolar Lavage (BAL) flui
TECHNIQUESMALDI Tof/Tof
OMICSProteomics
STUDY High Throughput
COMMENTSInvolved in cell migration and adhesion. Significantly upregulated by 2 fold.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18594147
DRUG TARGET
MONCLONAL ANTIBODYAnti-Plastin L Mouse/ Rat/ Human


Record No:44


ACCESS NO101443
GENELcn2
DESCRIPTIONLipocalin 2
NCBI ENTREZ ACCESS NO16819
UNIPROT ACCESS NOP11672
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3hours and 12 hours of fungal allergen induction in asthmatic mice.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGETBE0001084
MONCLONAL ANTIBODYAnti-Lipocalin 2 for Human


Record No:45


ACCESS NO101463
GENELilrb4
DESCRIPTIONLeukocyte immunoglobulin-like receptor subfamily B member 4
NCBI ENTREZ ACCESS NO14728
UNIPROT ACCESS NOQ64281
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSOverexpressed after 3hours and 12 hours of allergenic mould extract challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODY


Record No:46


ACCESS NO101473
GENELcp2
DESCRIPTIONLymphocyte cytosolic protein 2
NCBI ENTREZ ACCESS NO16822
UNIPROT ACCESS NOQ60787
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSOverexpressed after 3hours and 12 hours of allergenic mould extract challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-SLP76 for Mouse/Rat/Human


Record No:47


ACCESS NO101475
GENELtb
DESCRIPTIONLymphotoxin B
NCBI ENTREZ ACCESS NO16994
UNIPROT ACCESS NOP41155
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3 and 12 hours of fungal allergen challenge in asthmatic mice.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-Lymphotoxin Beta for Human


Record No:48


ACCESS NO101489
GENELif
DESCRIPTIONLeukemia inhibitory factor
NCBI ENTREZ ACCESS NO16878
UNIPROT ACCESS NOP09056
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3 and 12 hours of allergen induction in asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-LIF for Human


Record No:49


ACCESS NO101507
GENELmnb1
DESCRIPTIONLamin B1
NCBI ENTREZ ACCESS NO16906
UNIPROT ACCESS NOP14733
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3 and 12 hours of allergen induction in asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-Lamin B1 for Mouse/Rat/Human


Record No:50


ACCESS NO101521
GENELitaf
DESCRIPTIONLPS-induced TN factor
NCBI ENTREZ ACCESS NO56722
UNIPROT ACCESS NOQ9JLJ0
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3 and 12 hours of allergen induction in asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-LITAF for Human


Record No:51


ACCESS NO101527
GENELEP
DESCRIPTIONLeptin
NCBI ENTREZ ACCESS NO3952
UNIPROT ACCESS NOP41159
ORGANISMHuman
DISEASE PHENOTYPEAsthma rhinoconjunctivitis and eczema
SAMPLEEDTA added blood plasma
TECHNIQUESELISA
OMICSOthers
STUDY Low Throughput
COMMENTSHigh leptin were associated with increased persistence of asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE18331416
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:52


ACCESS NO101658
GENELgals1
DESCRIPTIONBeta galactoside binding protein
NCBI ENTREZ ACCESS NO16852
UNIPROT ACCESS NOP16045
ORGANISMMale BALB/c mice
DISEASE PHENOTYPEAllergic asthma
SAMPLELung tissue
TECHNIQUES2D electrophoresis and MALDI Tof Tof
OMICSProteomics
STUDY High Throughput
COMMENTSUpregulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE16100447
DRUG TARGETBE0004493
MONCLONAL ANTIBODYAnti-Galectin 1 for Mouse/Rat/Human


Record No:53


ACCESS NO101705
GENELCN2
DESCRIPTIONNeutrophil gelatinase-associated lipocalin (NGAL)
NCBI ENTREZ ACCESS NO3934
UNIPROT ACCESS NOP80188
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis neutrophilic granule protein is upregulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0001084
MONCLONAL ANTIBODYAnti-Lambda Light chain [LcN-2] for Human


Record No:54


ACCESS NO101737
GENELDHB
DESCRIPTIONL-Lactate dehydrogenase B chain
NCBI ENTREZ ACCESS NO3945
UNIPROT ACCESS NOF5H793
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0000068
MONCLONAL ANTIBODYAnti-Lactate Dehydrogenase B [60H11] for Mouse/Rat/Human


Record No:55


ACCESS NO101764
GENELBP
DESCRIPTIONdJ564F22.1 (lipopolysaccharide-binding protein)
NCBI ENTREZ ACCESS NO3929
UNIPROT ACCESS NOP18428
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis local matrix protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-LBP [EPR10865] for Human


Record No:56


ACCESS NO101792
GENELTF
DESCRIPTIONLactoferrin
NCBI ENTREZ ACCESS NO4057
UNIPROT ACCESS NOE7ER44
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis serum protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0000994
MONCLONAL ANTIBODYAnti-Lactoferrin [2B8] for Mouse/Rat/Human


Record No:57


ACCESS NO101803
GENELRG1
DESCRIPTIONLeucine-rich #-2-glycoprotein
NCBI ENTREZ ACCESS NO116844
UNIPROT ACCESS NOP02750
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis cytoskeletal protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYAnti-LRG1 [EPR12362] for Mouse/Rat/Human


Record No:58


ACCESS NO101849
GENELILRB2
DESCRIPTIONImmunoglobulin-like receptor subfamily B
NCBI ENTREZ ACCESS NO10288
UNIPROT ACCESS NOQ8N423
ORGANISMHuman
DISEASE PHENOTYPEAllergic Rhinitis induced by pollen allergen
SAMPLENasal lavage fluids
TECHNIQUESAffymetrix microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis anti inflammatory gene showed higher expression levels in patients than in controls.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15836756
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:59


ACCESS NO101924
GENELAMA5
DESCRIPTIONLaminin a-5 chain precursor
NCBI ENTREZ ACCESS NO3911
UNIPROT ACCESS NOO15230
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPeripheral blood eosinophils
TECHNIQUES2DE-PAGE and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic dermatitis patients eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15832365
DRUG TARGET
MONCLONAL ANTIBODYAnti-Laminin alpha 5 for Human


Record No:60


ACCESS NO101943
GENELATS2
DESCRIPTIONLATS large tumour suppressor homologue 2
NCBI ENTREZ ACCESS NO26524
UNIPROT ACCESS NOQ9NRM7
ORGANISMHuman(Asthmatic children)
DISEASE PHENOTYPEAsthma( Mite sensitized asthma)
SAMPLEPeripheral Blood Mononuclear Cells
TECHNIQUESMicroarray and RT-PCR
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in asthma. Involved in immune and lymphatic system development.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19187333
DRUG TARGET
MONCLONAL ANTIBODYAnti-LATS2 for Rat/Human


Record No:61


ACCESS NO101964
GENELIMK2
DESCRIPTIONLIM domain kinase 2
NCBI ENTREZ ACCESS NO3985
UNIPROT ACCESS NOP53671
ORGANISMHuman(Asthmatic children)
DISEASE PHENOTYPEAsthma( Mite sensitized asthma)
SAMPLEPeripheral Blood Mononuclear Cells
TECHNIQUESMicroarray and RT-PCR
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in asthmatic children. Involved in cellular function and maintenance.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19187333
DRUG TARGET
MONCLONAL ANTIBODYAnti-LIM kinase 2 for Mouse/Rat/Human


Record No:62


ACCESS NO101973
GENELAMA3
DESCRIPTIONLaminin alpha 3
NCBI ENTREZ ACCESS NO3909
UNIPROT ACCESS NOQ16787
ORGANISMHuman
DISEASE PHENOTYPEAsthma and allergic rhinitis
SAMPLEEpithelial cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSExpressed in patients with allergic rhinitis with or without asthma in upper airways.
GEO_PRIDE_ACCESS_NOGSE51392
REFERENCE24475887
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:63


ACCESS NO101986
GENELAMP2
DESCRIPTIONLysosomal-associated membrane protein 2
NCBI ENTREZ ACCESS NO3920
UNIPROT ACCESS NOP13473
ORGANISMHuman
DISEASE PHENOTYPEAsthma and allergic rhinitis
SAMPLEEpithelial cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDownregulated in patients with allergic rhinitis with or without asthma in the upper airways.
GEO_PRIDE_ACCESS_NOGSE51392
REFERENCE24475887
DRUG TARGET
MONCLONAL ANTIBODYAnti-LAMP2 for Mouse/Rabbit/Human


Record No:64


ACCESS NO102077
GENELIF
DESCRIPTIONLeukemia inhibitory factor
NCBI ENTREZ ACCESS NO3976
UNIPROT ACCESS NOP15018
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDifferentially expressed in asthma. Involved in inflammation and immunoregulation.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYAnti-LIF for Mouse/Human


Record No:65


ACCESS NO102105
GENELCP2
DESCRIPTIONLymphocyte cytosolic protein 2
NCBI ENTREZ ACCESS NO3937
UNIPROT ACCESS NOQ13094
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDifferentially expressed in asthma. Involved in TCR pathway and induces IL4.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYAnti-SLP76 for Mouse/Rat/Human


Record No:66


ACCESS NO102148
GENELGALS7
DESCRIPTIONLectin galactoside-binding soluble-7
NCBI ENTREZ ACCESS NO3963
UNIPROT ACCESS NOP47929
ORGANISMHuman
DISEASE PHENOTYPEAllergic asthma
SAMPLEBronchial Biopsy
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in allergic asthma.
GEO_PRIDE_ACCESS_NOGSE41649
REFERENCE19842841
DRUG TARGETBE0001008
MONCLONAL ANTIBODYAnti-Galectin for Human