BROWSE RESULT OF M
| 138 Records |
| ACCESS NO | 100069 |
| GENE | MX1 |
| DESCRIPTION | Myxovirus (influenza virus) resistance 1 interferon-inducible protein p78 |
| NCBI ENTREZ ACCESS NO | 4599 |
| UNIPROT ACCESS NO | P20591 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in innate immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | BE0000248 |
| MONCLONAL ANTIBODY | Anti-MX1 for Pig |
Record No:2
| ACCESS NO | 100070 |
| GENE | MNDA |
| DESCRIPTION | Myeloid cell nuclear differentiation antigen |
| NCBI ENTREZ ACCESS NO | 4332 |
| UNIPROT ACCESS NO | P41218 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in innate immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MNDA for Human |
Record No:3
| ACCESS NO | 100093 |
| GENE | MS4A4A |
| DESCRIPTION | Membrane-spanning 4-domains subfamily A member 4A |
| NCBI ENTREZ ACCESS NO | 51338 |
| UNIPROT ACCESS NO | Q96JQ5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene is associated with inflammation. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:4
| ACCESS NO | 100094 |
| GENE | MYL9 |
| DESCRIPTION | Myosin light chain 9 |
| NCBI ENTREZ ACCESS NO | 10398 |
| UNIPROT ACCESS NO | P24844 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene is associated with inflammation. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MYL9 [EPR13013(2)(B)] for Mouse/Rat/Human |
Record No:5
| ACCESS NO | 100098 |
| GENE | Muc5ac |
| DESCRIPTION | Mucin 5 subtypes A and C (tracheobronchial/gastric) |
| NCBI ENTREZ ACCESS NO | 17833 |
| UNIPROT ACCESS NO | E9QAQ8 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is an epithelial product and significantly upregulated in allergic asthma. It is induced upon allergen challenge and as well as combinatorial effect of IL-4 plus IL-13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mucin 5AC for Mouse/Human |
Record No:6
| ACCESS NO | 100111 |
| GENE | Mmp12 |
| DESCRIPTION | Matrix metalloproteinase 12 |
| NCBI ENTREZ ACCESS NO | 17381 |
| UNIPROT ACCESS NO | P34960 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This protease is commonly induced by allergens and Th2 cytokines such as IL-4 and IL-13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | BE0001198 |
| MONCLONAL ANTIBODY | Anti-MMP12 for Mouse/Rat/Human |
Record No:7
| ACCESS NO | 100154 |
| GENE | MUC5AC |
| DESCRIPTION | Mucin 5 subtypes A and C |
| NCBI ENTREZ ACCESS NO | 4586 |
| UNIPROT ACCESS NO | P98088 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mucin 5AC for Mouse/Human |
Record No:8
| ACCESS NO | 100165 |
| GENE | MUC5B |
| DESCRIPTION | Mucin 5 - subtype B |
| NCBI ENTREZ ACCESS NO | 727897 |
| UNIPROT ACCESS NO | Q9HC84 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MUC5B for Human |
Record No:9
| ACCESS NO | 100199 |
| GENE | MAF |
| DESCRIPTION | Transcription factor Maf |
| NCBI ENTREZ ACCESS NO | 4094 |
| UNIPROT ACCESS NO | O75444 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an transcription factor significantly downregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | BE0001527 |
| MONCLONAL ANTIBODY | N/A |
Record No:10
| ACCESS NO | 100208 |
| GENE | MICAL2 |
| DESCRIPTION | Microtubule associated monoxygenase calponin and LIM domain cont. 2 |
| NCBI ENTREZ ACCESS NO | 9645 |
| UNIPROT ACCESS NO | O94851 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene codes for a metabolic enzyme significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:11
| ACCESS NO | 100221 |
| GENE | MYL9 |
| DESCRIPTION | Myosin light polypeptide 9 |
| NCBI ENTREZ ACCESS NO | 10398 |
| UNIPROT ACCESS NO | P24844 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene codes for a calcium binding protein significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MYL9 [EPR13013(2)(B)] for Mouse/Rat/Human |
Record No:12
| ACCESS NO | 100222 |
| GENE | MATN2 |
| DESCRIPTION | Matrilin 2 |
| NCBI ENTREZ ACCESS NO | 4147 |
| UNIPROT ACCESS NO | O00339 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene codes for a calcium binding protein significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Matrilin 2 for Human |
Record No:13
| ACCESS NO | 100229 |
| GENE | METTL7A (DKFZP586A05 |
| DESCRIPTION | Methyltransferase like 7A |
| NCBI ENTREZ ACCESS NO | 25840 |
| UNIPROT ACCESS NO | Q9H8H3 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-METTL7A for Human |
Record No:14
| ACCESS NO | 100233 |
| GENE | MCTP1 |
| DESCRIPTION | Multiple C2-domains with two transmembrane regions 1 |
| NCBI ENTREZ ACCESS NO | 79772 |
| UNIPROT ACCESS NO | Q6DN14 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene is significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:15
| ACCESS NO | 100268 |
| GENE | MMP10 |
| DESCRIPTION | Matrix metallopeptidase 10 (stromelysin 2) |
| NCBI ENTREZ ACCESS NO | 4319 |
| UNIPROT ACCESS NO | P09238 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It helps in airway repair and remodelling. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | BE0003689 |
| MONCLONAL ANTIBODY | Anti-MMP10 for Human |
Record No:16
| ACCESS NO | 100292 |
| GENE | Map3k4 |
| DESCRIPTION | Mitogen-activated protein kinase kinase kinase 4 |
| NCBI ENTREZ ACCESS NO | 26407 |
| UNIPROT ACCESS NO | O08648 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is an intracellular protein involved in signal transduction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MAP3K4 for Mouse/Human |
Record No:17
| ACCESS NO | 100293 |
| GENE | Map3k7 |
| DESCRIPTION | Mitogen-activated protein kinase kinase kinase 7 |
| NCBI ENTREZ ACCESS NO | 26409 |
| UNIPROT ACCESS NO | Q62073 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in antigen presentation and cell mediated immune response. It exhibited 2 fold down regulation in allergic monocytes. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TAK1 for Mouse/Rat/Human |
Record No:18
| ACCESS NO | 100294 |
| GENE | Map3k8 |
| DESCRIPTION | Mitogen-activated protein kinase kinase kinase 8 |
| NCBI ENTREZ ACCESS NO | 26410 |
| UNIPROT ACCESS NO | Q07174 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in antigen presentation and cell mediated immune response. It exhibited 5 fold down regulation in allergic monocytes. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MAP3K8 for Human |
Record No:19
| ACCESS NO | 100311 |
| GENE | Mapk9 |
| DESCRIPTION | MAP Kinase 9 |
| NCBI ENTREZ ACCESS NO | 26420 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) and qRT- |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is a component of MAPK signalling pathway and Toll-like receptor signalling pathway. It is also involved in IgE receptor signalling pathway and controls focal adhesion. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | BE0003772 |
| MONCLONAL ANTIBODY | Anti-JNK2 for Mouse/Rat/Human |
Record No:20
| ACCESS NO | 100327 |
| GENE | Mt2A (MT-2) |
| DESCRIPTION | Metallothionein-2 |
| NCBI ENTREZ ACCESS NO | 689415 |
| UNIPROT ACCESS NO | P04355 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) and qRT- |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It may play a protective role in the early respone phase of asthma and may be a potential candidate antioxidant drug for asthma and inflammation. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Metallothionein for Mouse/Rat/Human |
Record No:21
| ACCESS NO | 100401 |
| GENE | MS4A2 (FCER1G) |
| DESCRIPTION | Membrane-spanning 4-domains-subfamily A- member 2 |
| NCBI ENTREZ ACCESS NO | 2207 |
| UNIPROT ACCESS NO | Q01362 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | gDNA |
| TECHNIQUES | Genotyping by PCR-RFLP |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | It plays a central role in signal transduction and helps transport the FceRI protein to the surface of mast cells and basophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21539617 |
| DRUG TARGET | BE0002139 |
| MONCLONAL ANTIBODY | N/A |
Record No:22
| ACCESS NO | 100402 |
| GENE | MMP9 |
| DESCRIPTION | Matrix metalloproteinase (MMP)-9 |
| NCBI ENTREZ ACCESS NO | 4318 |
| UNIPROT ACCESS NO | P14780 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Chronic urticaria |
| SAMPLE | Plasma |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This gene mainly contributes to inflammatory responses. It also plays a significant role in subsequent tissue remodelling and repair. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19317840 |
| DRUG TARGET | BE0000058 |
| MONCLONAL ANTIBODY | Anti-MMP9 for Mouse/Rat/Human |
Record No:23
| ACCESS NO | 100419 |
| GENE | MRPL12 |
| DESCRIPTION | 5c5-2 protein |
| NCBI ENTREZ ACCESS NO | 6182 |
| UNIPROT ACCESS NO | P52815 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | bronchial epithelial cells stimulated with TGF bet |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is upregulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20219718 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MRPL12 for Rat/Human |
Record No:24
| ACCESS NO | 100508 |
| GENE | Mmp12 |
| DESCRIPTION | Matrix metallo peptidase 12 |
| NCBI ENTREZ ACCESS NO | 17381 |
| UNIPROT ACCESS NO | P34960 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung eosinophil |
| TECHNIQUES | Compugen mouse 22K oligonucleotide microarrays and |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is upregulated in asthma |
| GEO_PRIDE_ACCESS_NO | GSE15345 |
| REFERENCE | 19395375 |
| DRUG TARGET | BE0001198 |
| MONCLONAL ANTIBODY | Anti-Mmp12 for Human/Rabbit/Mouse |
Record No:25
| ACCESS NO | 100526 |
| GENE | Mmp14 |
| DESCRIPTION | Matrix metallopeptidase 14 |
| NCBI ENTREZ ACCESS NO | 17387 |
| UNIPROT ACCESS NO | P53690 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Macrophages from Broncho Alveolar Lavage (BAL) and |
| TECHNIQUES | Illumina gene chip microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23685352 |
| DRUG TARGET | BE0003692 |
| MONCLONAL ANTIBODY | Anti-MMP14 for Human/Rat/Mouse |
Record No:26
| ACCESS NO | 100536 |
| GENE | Muc5ac |
| DESCRIPTION | Mucin 5 subtypes A and C |
| NCBI ENTREZ ACCESS NO | 17833 |
| UNIPROT ACCESS NO | E9PWB6 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Tissue from left lung |
| TECHNIQUES | Affymetrix gene chip cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is responsible for mucus production and goblet cell hyperplasia. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18087161 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mucin 5AC for Human/Mouse |
Record No:27
| ACCESS NO | 100551 |
| GENE | Muc5ac |
| DESCRIPTION | Mucin 5 subtypes A and C |
| NCBI ENTREZ ACCESS NO | 17833 |
| UNIPROT ACCESS NO | E9PWB6 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Tissue from bronchial biopsy |
| TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Mucus production and goblet cell hyperplasia (data collected from supplementary table). |
| GEO_PRIDE_ACCESS_NO | GSE15823 |
| REFERENCE | 15038835 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MUCin 5AC for Human/Mouse |
Record No:28
| ACCESS NO | 100552 |
| GENE | Muc2 |
| DESCRIPTION | Mucin 2 |
| NCBI ENTREZ ACCESS NO | 17831 |
| UNIPROT ACCESS NO | Q80Z19 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Tissue from bronchial biopsy |
| TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Mucus production and goblet cell hyperplasia (data collected from supplementary table). |
| GEO_PRIDE_ACCESS_NO | GSE15823 |
| REFERENCE | 15038835 |
| DRUG TARGET | BE0001034 |
| MONCLONAL ANTIBODY | Anti-MUC2 for Rat/Human/Mouse |
Record No:29
| ACCESS NO | 100587 |
| GENE | MST1 |
| DESCRIPTION | Macrophage-stimulatory protein |
| NCBI ENTREZ ACCESS NO | 4485 |
| UNIPROT ACCESS NO | Q13043 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MST1 for Human/Rat/Mouse |
Record No:30
| ACCESS NO | 100589 |
| GENE | MPO |
| DESCRIPTION | Myeloperoxidase |
| NCBI ENTREZ ACCESS NO | 4353 |
| UNIPROT ACCESS NO | P05164 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthmatic airways after allergen challenge |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0001075 |
| MONCLONAL ANTIBODY | Anti-Myeloperoxidase for Human |
Record No:31
| ACCESS NO | 100610 |
| GENE | MT-CO2 |
| DESCRIPTION | Cyclooxygenase-2 |
| NCBI ENTREZ ACCESS NO | 4513 |
| UNIPROT ACCESS NO | P00403 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Pulmonary inflammation and effects of diesel particles |
| SAMPLE | Airway epithelial cells |
| TECHNIQUES | ChIP and HDAC/HAT assay |
| OMICS | Epigenetics |
| STUDY | Low Throughput |
| COMMENTS | Loss of HDAC1 increases cyclooxygenase expression during exposure to diesel exhaust particles. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17395887 |
| DRUG TARGET | BE0003385 |
| MONCLONAL ANTIBODY | Anti-MTCO2 for Human |
Record No:32
| ACCESS NO | 100697 |
| GENE | Mmp12 |
| DESCRIPTION | Matrix metallopeptidase 12 |
| NCBI ENTREZ ACCESS NO | 17381 |
| UNIPROT ACCESS NO | P34960 |
| ORGANISM | TSLP TG mice and BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid Broncho Alveol |
| TECHNIQUES | LC-MS/MS and Western blot and qRT PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Involved in cellular inflammation in the lung. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22837640 |
| DRUG TARGET | BE0001198 |
| MONCLONAL ANTIBODY | Anti-MMP12 for Mouse/rat/human |
Record No:33
| ACCESS NO | 100716 |
| GENE | MCSF |
| DESCRIPTION | Macrophage colony stimulating factor 1 |
| NCBI ENTREZ ACCESS NO | 1435 |
| UNIPROT ACCESS NO | P09603 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis treatment with glucocorticoid |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | iTRAQ based proteomics nano LC MS/MS gene expressi |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Causes proliferation of T cells and increased after treatment of asthma patients with glucocorticoids |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20659080 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MCSF for Human |
Record No:34
| ACCESS NO | 100738 |
| GENE | MEPE |
| DESCRIPTION | matrix extracellular phosphoglycoprotein |
| NCBI ENTREZ ACCESS NO | 56955 |
| UNIPROT ACCESS NO | Q9NQ76 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Perpheral blood mononuclear cells |
| TECHNIQUES | Oligonucleotide microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Associated with oncogenic osteomalacia and hypophosphatemic rickets. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21966607 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:35
| ACCESS NO | 100739 |
| GENE | MLSTD1 |
| DESCRIPTION | fatty acyl CoA reductase 2 |
| NCBI ENTREZ ACCESS NO | 55711 |
| UNIPROT ACCESS NO | Q96K12 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Perpheral blood mononuclear cells |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Fatty alcohol synthesis in mammals. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21966607 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:36
| ACCESS NO | 100756 |
| GENE | Madd |
| DESCRIPTION | Map kinase-activating death domain protein |
| NCBI ENTREZ ACCESS NO | 228355 |
| UNIPROT ACCESS NO | Q80U28 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after fungal allergen challenge. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-DENN for Mouse/Rat/Human |
Record No:37
| ACCESS NO | 100757 |
| GENE | Mapk8ip |
| DESCRIPTION | Mitogen-activated protein kinase 8 interacting protein 1 |
| NCBI ENTREZ ACCESS NO | 19099 |
| UNIPROT ACCESS NO | Q3UI81 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after allergen challenge.Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:38
| ACCESS NO | 100758 |
| GENE | Mapk9 |
| DESCRIPTION | Mitogen-activated protein kinase 9 |
| NCBI ENTREZ ACCESS NO | 26420 |
| UNIPROT ACCESS NO | Q9WTU6 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after allergen challenge.Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | BE0003772 |
| MONCLONAL ANTIBODY | Anti-JNK2 for Mouse/Rat/Human |
Record No:39
| ACCESS NO | 100759 |
| GENE | Mll3 |
| DESCRIPTION | Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog |
| NCBI ENTREZ ACCESS NO | 231051 |
| UNIPROT ACCESS NO | F8WI37 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after allergen challenge.Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:40
| ACCESS NO | 100780 |
| GENE | MYLK |
| DESCRIPTION | Myosin light chain kinase |
| NCBI ENTREZ ACCESS NO | 4638 |
| UNIPROT ACCESS NO | Q15746 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | DNA |
| TECHNIQUES | Illumina Human Hap 550Kv3 BeadChip SNP array |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | rs11718105 SNP is associated with asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19264973 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MYLK2 for Human |
Record No:41
| ACCESS NO | 100808 |
| GENE | Mad2l1 |
| DESCRIPTION | Mitotic spindle assembly checkpoint protein |
| NCBI ENTREZ ACCESS NO | 56150 |
| UNIPROT ACCESS NO | Q9Z1B5 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in cell cycle regulation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mad2L1 for Human |
Record No:42
| ACCESS NO | 100809 |
| GENE | Mcm6 |
| DESCRIPTION | DNA replication licencing factor |
| NCBI ENTREZ ACCESS NO | 17219 |
| UNIPROT ACCESS NO | P97311 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in DNA replication. Potential new target for asthma |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:43
| ACCESS NO | 100810 |
| GENE | Mki67 |
| DESCRIPTION | Marker of proliferation Ki-67 |
| NCBI ENTREZ ACCESS NO | 17345 |
| UNIPROT ACCESS NO | E9PVX6 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in short time allergen exposure and downregulated in long exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Ki67 for Mouse/Rat/Human |
Record No:44
| ACCESS NO | 100830 |
| GENE | Mmp12 |
| DESCRIPTION | Macrophage metalloprotease |
| NCBI ENTREZ ACCESS NO | 17381 |
| UNIPROT ACCESS NO | P34960 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Highly expressed after short term allergen exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0001198 |
| MONCLONAL ANTIBODY | Anti-MMP12 for Mouse/rat/human |
Record No:45
| ACCESS NO | 100836 |
| GENE | MOR38-2 |
| DESCRIPTION | Olfactory receptor |
| NCBI ENTREZ ACCESS NO | 258377 |
| UNIPROT ACCESS NO | Q8VF27 |
| ORGANISM | SWR/J mouse |
| DISEASE PHENOTYPE | Allergic conjunctivitis |
| SAMPLE | Conjunctival Tissues |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is an olfactory receptor upregulated in conjunctiva. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18658092 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:46
| ACCESS NO | 100928 |
| GENE | Meg3 |
| DESCRIPTION | Maternally expressed 3 |
| NCBI ENTREZ ACCESS NO | 17263 |
| UNIPROT ACCESS NO | |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after induction with all three food allergens. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:47
| ACCESS NO | 100937 |
| GENE | Mgam |
| DESCRIPTION | Maltase-glucoamylase |
| NCBI ENTREZ ACCESS NO | 232714 |
| UNIPROT ACCESS NO | B5THE2 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after induction with food allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | BE0000837 |
| MONCLONAL ANTIBODY | N/A |
Record No:48
| ACCESS NO | 100946 |
| GENE | MCP3 |
| DESCRIPTION | Monocyte chemotactic protein |
| NCBI ENTREZ ACCESS NO | 6354 |
| UNIPROT ACCESS NO | P80098 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Genomic DNA from Peripheral blood leukocytes |
| TECHNIQUES | PCR and Electrophoretic mobility shift assay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Promoter polymorphism is associated with asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21388664 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MCP3 for Rat/Human |
Record No:49
| ACCESS NO | 100952 |
| GENE | MUC5AC |
| DESCRIPTION | Mucin 5AC |
| NCBI ENTREZ ACCESS NO | 4586 |
| UNIPROT ACCESS NO | P98088 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Trachea section |
| TECHNIQUES | immunofloresence immunoblotting RT PCR |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Activated by Agr2 and helps in the production of mucins. Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22403803 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mucin 5AC for Mouse/Human |
Record No:50
| ACCESS NO | 100958 |
| GENE | MIP-1 |
| DESCRIPTION | Macrophage inflammatory proteins 1 |
| NCBI ENTREZ ACCESS NO | 6348 |
| UNIPROT ACCESS NO | P10147 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in Obese patients |
| SAMPLE | Peripheral Blood mononuclear cells |
| TECHNIQUES | Flow cytometry and immunoflorescent staining |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Overexpressed in obese patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23760409 |
| DRUG TARGET | BE0002471 |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 1 alpha for Human |
Record No:51
| ACCESS NO | 100961 |
| GENE | Mir21 |
| DESCRIPTION | Micro RNA 21 |
| NCBI ENTREZ ACCESS NO | 387140 |
| UNIPROT ACCESS NO | |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic airway inflammation |
| SAMPLE | Lung tissue |
| TECHNIQUES | Micro RNA microarray and RT-PCR |
| OMICS | Epigenetics |
| STUDY | High Throughput |
| COMMENTS | It is a micro-RNA whose target is mIL-12p35. Decrease in mIL-12p35 leads to polarization TH cells to TH2 response. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19342679 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:52
| ACCESS NO | 100964 |
| GENE | MIR18A |
| DESCRIPTION | miR-18a |
| NCBI ENTREZ ACCESS NO | 406953 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Long-term asthma with and without allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | Real-Time Quantitative RT-PCR and miRNA Assay |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This miRNA is down regulated in asthma with or without allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24513959 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:53
| ACCESS NO | 100965 |
| GENE | MIR126 |
| DESCRIPTION | miR-126 |
| NCBI ENTREZ ACCESS NO | 406913 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Long-term asthma with and without allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | Real-Time Quantitative RT-PCR and miRNA Assay |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This miRNA is down regulated in asthma with or without allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24513959 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:54
| ACCESS NO | 100966 |
| GENE | MIR155 |
| DESCRIPTION | miR-155 |
| NCBI ENTREZ ACCESS NO | 406947 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Long-term asthma with and without allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | Real-Time Quantitative RT-PCR and miRNA Assay |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This miRNA is down regulated in asthma with or without allergic rhinitis. Its expression also positively correlates with exhaled nitric oxide and Th2 cytokines. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24513959 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:55
| ACCESS NO | 100967 |
| GENE | MIR498 |
| DESCRIPTION | miR-498 |
| NCBI ENTREZ ACCESS NO | 574460 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Long-term asthma with and without allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | Real-Time Quantitative RT-PCR and miRNA Assay |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This miRNA is up regulated in asthma with or without allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24513959 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:56
| ACCESS NO | 100968 |
| GENE | MIR187 |
| DESCRIPTION | miR-187 |
| NCBI ENTREZ ACCESS NO | 406963 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Long-term asthma with and without allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | Real-Time Quantitative RT-PCR and miRNA Assay |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This miRNA is up regulated in asthma with allergic rhinitis . |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24513959 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:57
| ACCESS NO | 100969 |
| GENE | MIRLET7E |
| DESCRIPTION | let-7E |
| NCBI ENTREZ ACCESS NO | 406887 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Long-term asthma with and without allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | Real-Time Quantitative RT-PCR and miRNA Assay |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This miRNA is down regulated in persistent and non-persistent asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24513959 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:58
| ACCESS NO | 100970 |
| GENE | MIR224 |
| DESCRIPTION | miR-224 |
| NCBI ENTREZ ACCESS NO | 407009 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Long-term asthma with and without allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | Real-Time Quantitative RT-PCR and miRNA Assay |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This miRNA is down regulated in non-persistent asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24513959 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:59
| ACCESS NO | 100971 |
| GENE | MIR874 |
| DESCRIPTION | miR-874 |
| NCBI ENTREZ ACCESS NO | 100126343 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Long-term asthma with and without allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | Real-Time Quantitative RT-PCR and miRNA Assay |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This miRNA is down regulated in persistent asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24513959 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:60
| ACCESS NO | 100972 |
| GENE | MIR143 |
| DESCRIPTION | miR-143 |
| NCBI ENTREZ ACCESS NO | 406935 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Long-term asthma with and without allergic rhinitis |
| SAMPLE | Nasal mucosa |
| TECHNIQUES | Real-Time Quantitative RT-PCR and miRNA Assay |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | This miRNA is down regulated in persistent asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24513959 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:61
| ACCESS NO | 101047 |
| GENE | MYH9 |
| DESCRIPTION | Myosin-9 |
| NCBI ENTREZ ACCESS NO | 4627 |
| UNIPROT ACCESS NO | P35579 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly down regulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:62
| ACCESS NO | 101062 |
| GENE | MMP9 |
| DESCRIPTION | Matrix metalloproteinase - 9 |
| NCBI ENTREZ ACCESS NO | 4318 |
| UNIPROT ACCESS NO | P14780 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma |
| TECHNIQUES | ELISA and zymography |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Level of this marker was significantly higher in acute exacerbation and decreased in remission but remained significantly higher compared to healthy controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24073339 |
| DRUG TARGET | BE0000058 |
| MONCLONAL ANTIBODY | Anti-MMP9 for Rat/Human |
Record No:63
| ACCESS NO | 101073 |
| GENE | MMP25 |
| DESCRIPTION | Leukolysin |
| NCBI ENTREZ ACCESS NO | 64386 |
| UNIPROT ACCESS NO | Q9NPA2 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | BE0003700 |
| MONCLONAL ANTIBODY | Anti-MMP25 for Human |
Record No:64
| ACCESS NO | 101099 |
| GENE | MED24 |
| DESCRIPTION | Mediator complex subunit 24 |
| NCBI ENTREZ ACCESS NO | 9862 |
| UNIPROT ACCESS NO | O75448 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | gDNA |
| TECHNIQUES | SNP typing |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | SNP related alleles of this gene in combination with deregulated phosphatidylcholines in asthmatics may serve as biomarker of this disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23452035 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:65
| ACCESS NO | 101103 |
| GENE | MIR22 |
| DESCRIPTION | Micro RNA 22 |
| NCBI ENTREZ ACCESS NO | 407004 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:66
| ACCESS NO | 101104 |
| GENE | MIR132 |
| DESCRIPTION | Micro RNA 132 |
| NCBI ENTREZ ACCESS NO | 406921 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:67
| ACCESS NO | 101105 |
| GENE | MIR21 |
| DESCRIPTION | Micro RNA 21 |
| NCBI ENTREZ ACCESS NO | 406991 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:68
| ACCESS NO | 101106 |
| GENE | MIR23A |
| DESCRIPTION | Micro RNA 23A |
| NCBI ENTREZ ACCESS NO | 407010 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:69
| ACCESS NO | 101107 |
| GENE | MIR374A |
| DESCRIPTION | Micro RNA 374A |
| NCBI ENTREZ ACCESS NO | 442919 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:70
| ACCESS NO | 101108 |
| GENE | MIR27A |
| DESCRIPTION | Micro RNA 27A |
| NCBI ENTREZ ACCESS NO | 407018 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:71
| ACCESS NO | 101109 |
| GENE | MIR146A |
| DESCRIPTION | Micro RNA 146A |
| NCBI ENTREZ ACCESS NO | 406938 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:72
| ACCESS NO | 101110 |
| GENE | MIR15A |
| DESCRIPTION | Micro RNA 15A |
| NCBI ENTREZ ACCESS NO | 406948 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:73
| ACCESS NO | 101111 |
| GENE | MIR421 |
| DESCRIPTION | Micro RNA 421 |
| NCBI ENTREZ ACCESS NO | 693122 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:74
| ACCESS NO | 101112 |
| GENE | MIR155 |
| DESCRIPTION | Micro RNA 155 |
| NCBI ENTREZ ACCESS NO | 406947 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:75
| ACCESS NO | 101113 |
| GENE | MIR222 |
| DESCRIPTION | Micro RNA 222 |
| NCBI ENTREZ ACCESS NO | 407007 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:76
| ACCESS NO | 101114 |
| GENE | MIR221 |
| DESCRIPTION | Micro RNA 221 |
| NCBI ENTREZ ACCESS NO | 407006 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:77
| ACCESS NO | 101115 |
| GENE | MIR181C |
| DESCRIPTION | Micro RNA 181C |
| NCBI ENTREZ ACCESS NO | 406957 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:78
| ACCESS NO | 101116 |
| GENE | MIR874 |
| DESCRIPTION | Micro RNA 874 |
| NCBI ENTREZ ACCESS NO | 100126343 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:79
| ACCESS NO | 101117 |
| GENE | MIR193B |
| DESCRIPTION | Micro RNA 193B |
| NCBI ENTREZ ACCESS NO | 574455 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:80
| ACCESS NO | 101118 |
| GENE | MIR99A |
| DESCRIPTION | Micro RNA 99A |
| NCBI ENTREZ ACCESS NO | 407055 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4-/+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:81
| ACCESS NO | 101119 |
| GENE | MIR130B |
| DESCRIPTION | Micro RNA 130B |
| NCBI ENTREZ ACCESS NO | 406920 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be upregulated in CCR4+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:82
| ACCESS NO | 101120 |
| GENE | MIR454 |
| DESCRIPTION | Micro RNA 454 |
| NCBI ENTREZ ACCESS NO | 768216 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be upregulated in CCR4+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:83
| ACCESS NO | 101121 |
| GENE | MIR185 |
| DESCRIPTION | Micro RNA 185 |
| NCBI ENTREZ ACCESS NO | 406961 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be upregulated in CCR4+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:84
| ACCESS NO | 101122 |
| GENE | MIR30B |
| DESCRIPTION | Micro RNA 30B |
| NCBI ENTREZ ACCESS NO | 407030 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Circulating T-cells |
| TECHNIQUES | High-throughput nano-scale qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This miRNA was found to be down regulated in CCR4+ circulating T- cells in different asthma groups. |
| GEO_PRIDE_ACCESS_NO | GSE31030 |
| REFERENCE | 23304658 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:85
| ACCESS NO | 101136 |
| GENE | MRC1 (CD206) |
| DESCRIPTION | CD206 molecule |
| NCBI ENTREZ ACCESS NO | 4360 |
| UNIPROT ACCESS NO | P22897 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Monocytes derived macrophage |
| TECHNIQUES | Flow cytometry and Real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Cytokinexpressed significantly more HLA-DR . |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22981793 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:86
| ACCESS NO | 101165 |
| GENE | MX1 |
| DESCRIPTION | Myxovirus (influenza virus) resistance 1 |
| NCBI ENTREZ ACCESS NO | 4599 |
| UNIPROT ACCESS NO | P20591 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
| SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
| TECHNIQUES | 2D-DIGE and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene was overexpressed after LPS challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22464673 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MX1 for Pig |
Record No:87
| ACCESS NO | 101170 |
| GENE | MRC1 (CD206) |
| DESCRIPTION | CD206 molecule |
| NCBI ENTREZ ACCESS NO | 4360 |
| UNIPROT ACCESS NO | P22897 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
| SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
| TECHNIQUES | Label free nano-LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is overexpressed in various types of tolerogenic dendritic cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22464673 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mannose Receptor for Mouse/Human |
Record No:88
| ACCESS NO | 101183 |
| GENE | Muc5ac |
| DESCRIPTION | Mucin 5 subtypes A and C (tracheobronchial/gastric) |
| NCBI ENTREZ ACCESS NO | 17833 |
| UNIPROT ACCESS NO | E9QAQ8 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effect of a bioactive flavonol Fisetin |
| SAMPLE | Lung tissue |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Fisetin attenuated ovalbumin-induced expression of this gene. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22290391 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mucin 5AC for Mouse/Human |
Record No:89
| ACCESS NO | 101185 |
| GENE | MIR1248 |
| DESCRIPTION | microRNA 1248 |
| NCBI ENTREZ ACCESS NO | 100302143 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | miR-1248 is predicted to regulate IL5 post-transcriptionally. It physically interacts with the IL-5 transcript in the 3' untranslated region and serves as a positive regulator to increase IL-5 expression. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23885321 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:90
| ACCESS NO | 101186 |
| GENE | MIRLET7D |
| DESCRIPTION | microRNA let-7d |
| NCBI ENTREZ ACCESS NO | 406886 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | It is downregulated in asthma. It regulated the expression of IL-13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23885321 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:91
| ACCESS NO | 101187 |
| GENE | MIR26A1 |
| DESCRIPTION | microRNA 26a |
| NCBI ENTREZ ACCESS NO | 407015 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | It is downregulated in asthma. It regulated the expression of TGF beta receptor. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23885321 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:92
| ACCESS NO | 101188 |
| GENE | Mirlet7a-1 |
| DESCRIPTION | microRNA let7a |
| NCBI ENTREZ ACCESS NO | 387244 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | It is downregulated in asthma. It regulated the expression of IL-13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23885321 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:93
| ACCESS NO | 101212 |
| GENE | MOK |
| DESCRIPTION | MAPK/MAK/MRK overlapping kinase |
| NCBI ENTREZ ACCESS NO | 5891 |
| UNIPROT ACCESS NO | Q9UQ07 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be upregulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:94
| ACCESS NO | 101213 |
| GENE | MCEMP1 |
| DESCRIPTION | Mast cell expressed membrane protein 1 |
| NCBI ENTREZ ACCESS NO | 199675 |
| UNIPROT ACCESS NO | Q8IX19 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MCEMP1 [EPR14393] for Human |
Record No:95
| ACCESS NO | 101214 |
| GENE | MAP3K4 |
| DESCRIPTION | Mitogen-activated protein kinase kinase kinase 4 |
| NCBI ENTREZ ACCESS NO | 4216 |
| UNIPROT ACCESS NO | Q9Y6R4 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MAP3K4 for Mouse/Human |
Record No:96
| ACCESS NO | 101215 |
| GENE | MYO1C |
| DESCRIPTION | Myosin-Ic |
| NCBI ENTREZ ACCESS NO | 4641 |
| UNIPROT ACCESS NO | O00159 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:97
| ACCESS NO | 101247 |
| GENE | Muc5ac |
| DESCRIPTION | Mucin 5 subtypes A and C (tracheobronchial/gastric) |
| NCBI ENTREZ ACCESS NO | 17833 |
| UNIPROT ACCESS NO | E9QAQ8 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
| SAMPLE | Lung tissue |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Pretreatment with artesunate (30 mg/kg) demonstrated strong suppression of this gene that is essential for mucus hypersecretion. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mucin 5AC for Mouse/Human |
Record No:98
| ACCESS NO | 101279 |
| GENE | MMP-9 |
| DESCRIPTION | Matrix metallopeptidase 9 |
| NCBI ENTREZ ACCESS NO | 4318 |
| UNIPROT ACCESS NO | P14780 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma (The effect of aspirin desensitization) |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Decreased significantly after aspirin treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20728206 |
| DRUG TARGET | BE0000058 |
| MONCLONAL ANTIBODY | Anti-MMP9 for Human/Rat |
Record No:99
| ACCESS NO | 101292 |
| GENE | MIF |
| DESCRIPTION | Macrophage migration inhibitory factor |
| NCBI ENTREZ ACCESS NO | 4282 |
| UNIPROT ACCESS NO | P14174 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in children |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0001855 |
| MONCLONAL ANTIBODY | Anti-MIF for Mouse/Rat/Human |
Record No:100
| ACCESS NO | 101295 |
| GENE | MIP-1a |
| DESCRIPTION | Chemokine (C-C motif) ligand 3 |
| NCBI ENTREZ ACCESS NO | 6348 |
| UNIPROT ACCESS NO | P10147 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in children |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0002471 |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 for Human |
Record No:101
| ACCESS NO | 101299 |
| GENE | Mpo |
| DESCRIPTION | Myeloperoxidase |
| NCBI ENTREZ ACCESS NO | 303413 |
| UNIPROT ACCESS NO | D3ZGE2 |
| ORGANISM | Male Sprague–Dawley rats |
| DISEASE PHENOTYPE | Asthma(Effect of vasoactive peptide in OVA challenged rats) |
| SAMPLE | Broncho alveolar lavage fluid |
| TECHNIQUES | Biochemical tests |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased after OVA challenge but decreased on administering Vasoactive Intestinal Peptide. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19808073 |
| DRUG TARGET | BE0001075 |
| MONCLONAL ANTIBODY | Anti-Myeloperoxidase for Human |
Record No:102
| ACCESS NO | 101302 |
| GENE | MMP-9 |
| DESCRIPTION | Metalloproteinase-9 |
| NCBI ENTREZ ACCESS NO | 4318 |
| UNIPROT ACCESS NO | P14780 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Childhood asthma |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19788537 |
| DRUG TARGET | BE0000058 |
| MONCLONAL ANTIBODY | Anti-MMP9 for Rat/Human |
Record No:103
| ACCESS NO | 101338 |
| GENE | Muc5ac |
| DESCRIPTION | Mucin 5 subtypes A and C |
| NCBI ENTREZ ACCESS NO | 17833 |
| UNIPROT ACCESS NO | E9PWB6 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Asthma (Effect of andrographolide on NF kappa beta pathway in asthma) |
| SAMPLE | Bronchial Epithelial cells |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Strongly downregulated after andrographolide treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19201922 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mucin 5AC for Human/Mouse |
Record No:104
| ACCESS NO | 101355 |
| GENE | Msn |
| DESCRIPTION | Moesin |
| NCBI ENTREZ ACCESS NO | 17698 |
| UNIPROT ACCESS NO | P26041 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in F actin reorganisation which is essential for cellular adhesion migration inflammation and phagocytosis. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Moesin for Mouse/Rat/Human |
Record No:105
| ACCESS NO | 101379 |
| GENE | Mtpn |
| DESCRIPTION | Myotrophin |
| NCBI ENTREZ ACCESS NO | 14489 |
| UNIPROT ACCESS NO | P62774 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in chronic asthma mouse model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:106
| ACCESS NO | 101421 |
| GENE | Msr1 |
| DESCRIPTION | Macrophage scavenger receptor 1 |
| NCBI ENTREZ ACCESS NO | 20288 |
| UNIPROT ACCESS NO | P30204 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Macrophage Scavenger Receptor I antibody for Mouse/Rat/Human |
Record No:107
| ACCESS NO | 101446 |
| GENE | Mcoln2 |
| DESCRIPTION | Mucolipin 2 |
| NCBI ENTREZ ACCESS NO | 68279 |
| UNIPROT ACCESS NO | Q8K595 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3hours and 12 hours of fungal allergen induction in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:108
| ACCESS NO | 101449 |
| GENE | Mmp9 |
| DESCRIPTION | Matrix metallopeptidase 9 |
| NCBI ENTREZ ACCESS NO | 17395 |
| UNIPROT ACCESS NO | P41245 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in collagen deposition. Upregulated after 3hours and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0000058 |
| MONCLONAL ANTIBODY | Anti-MMP9 for Rat/Human |
Record No:109
| ACCESS NO | 101467 |
| GENE | Marcksl1 |
| DESCRIPTION | MARCKS-like 1 |
| NCBI ENTREZ ACCESS NO | 17357 |
| UNIPROT ACCESS NO | P28667 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:110
| ACCESS NO | 101488 |
| GENE | Myd88 |
| DESCRIPTION | Myeloid differentiation primary response gene 88 |
| NCBI ENTREZ ACCESS NO | 17874 |
| UNIPROT ACCESS NO | P22366 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MyD88 for Human |
Record No:111
| ACCESS NO | 101490 |
| GENE | Maff |
| DESCRIPTION | V-maf musculoaponeurotic fibrosarcoma oncogene family protein F |
| NCBI ENTREZ ACCESS NO | 17133 |
| UNIPROT ACCESS NO | O54791 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:112
| ACCESS NO | 101548 |
| GENE | Muc5ac |
| DESCRIPTION | Mucin 5 subtypes A and C |
| NCBI ENTREZ ACCESS NO | 17833 |
| UNIPROT ACCESS NO | E9PWB6 |
| ORGANISM | Female Balb/c Mice |
| DISEASE PHENOTYPE | Asthma(Effect of Glycogen synthase kinase-3 beta inhibition on asthma) |
| SAMPLE | Lung tissue |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Involved in mucin production.Expressed in OVA challenged mouse but decreased in presence of Gsk3b inhibitor. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17556716 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mucin 5AC for Mouse/Human |
Record No:113
| ACCESS NO | 101552 |
| GENE | MCP-1 |
| DESCRIPTION | Chemokine (C-C motif) ligand 2 |
| NCBI ENTREZ ACCESS NO | 20296 |
| UNIPROT ACCESS NO | P10148 |
| ORGANISM | Female Balb/c Mice |
| DISEASE PHENOTYPE | Asthma(Effect of Glycogen synthase kinase-3 beta inhibition on asthma) |
| SAMPLE | Lung tissue |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Gsk3b inhibitor blocked the expression of IL8. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17556716 |
| DRUG TARGET | BE0001047 |
| MONCLONAL ANTIBODY | Anti-MCP1 for Mouse/Human |
Record No:114
| ACCESS NO | 101578 |
| GENE | Mmel |
| DESCRIPTION | Matrix metallopeptidase 12 |
| NCBI ENTREZ ACCESS NO | 17381 |
| UNIPROT ACCESS NO | P34960 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | A protease expressed after induction with IL 13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:115
| ACCESS NO | 101610 |
| GENE | Mod1 |
| DESCRIPTION | Chromobox 1 |
| NCBI ENTREZ ACCESS NO | 12412 |
| UNIPROT ACCESS NO | P83917 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in metabolism and expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:116
| ACCESS NO | 101644 |
| GENE | MRC1 |
| DESCRIPTION | Mannose receptor C type 1 |
| NCBI ENTREZ ACCESS NO | 4360 |
| UNIPROT ACCESS NO | P22897 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Insect allergy(Bee venom immunotherapy) |
| SAMPLE | Peripheral Blood Mononuclear cells |
| TECHNIQUES | Gene chip microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Involved in osteopontin regulatory pathway. Expressed after venom immunotherapy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15867867 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mannose Receptor for Mouse/Human |
Record No:117
| ACCESS NO | 101650 |
| GENE | Myl2 |
| DESCRIPTION | Myosin light chain 2 |
| NCBI ENTREZ ACCESS NO | 17906 |
| UNIPROT ACCESS NO | P51667 |
| ORGANISM | Male BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | 2D electrophoresis and MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16100447 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Myosin Light Chain 2 for Mouse/Rat/Human |
Record No:118
| ACCESS NO | 101654 |
| GENE | Mybpc3 |
| DESCRIPTION | Myosin binding protein C |
| NCBI ENTREZ ACCESS NO | 17868 |
| UNIPROT ACCESS NO | O70468 |
| ORGANISM | Male BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | 2D electrophoresis and MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16100447 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MYBPC3 for Mouse/Rat/Human |
Record No:119
| ACCESS NO | 101682 |
| GENE | Mirlet7a-1 (mmu-let- |
| DESCRIPTION | microRNA let7a-1 |
| NCBI ENTREZ ACCESS NO | 387244 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and its modulation by microRNA |
| SAMPLE | Lung tissue |
| TECHNIQUES | Microarray and real time PCR along with certain re |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It plays a potent proinflammatory role in allergic lung disease. Inhibition of let-7 miRNAs using a locked nucleic acid (anti sense) profoundly inhibited production of allergic cytokines and the disease phenotype. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20630862 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:120
| ACCESS NO | 101690 |
| GENE | Mfge8 |
| DESCRIPTION | Milk Fat Globule-EGF factor 8 |
| NCBI ENTREZ ACCESS NO | 17304 |
| UNIPROT ACCESS NO | P21956 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Smooth muscle cells of lung tissue |
| TECHNIQUES | Standard molecular biology and cell biology techni |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | In absence of this gene the airway hyper-responsiveness is highly exaggerated. Treatment with recombinant Mfge8 causes attenuation of airway inflammation by inhibiting IL-13–induced NF-κB activation and induction of RhoA. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23269839 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Milk Fat Globule 1 [EDM45] for Human |
Record No:121
| ACCESS NO | 101696 |
| GENE | MST1 |
| DESCRIPTION | Hepatocyte growth factor-like protein |
| NCBI ENTREZ ACCESS NO | 3083 |
| UNIPROT ACCESS NO | Q04756 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This growth factor is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MST1 [EP1465Y] for Mouse/Rat/Human |
Record No:122
| ACCESS NO | 101704 |
| GENE | MMP9 (MMP-9) |
| DESCRIPTION | Matrix metallopeptidase 9 (gelatinase B or 92kDa gelatinase or 92kDa type IV collagenase) |
| NCBI ENTREZ ACCESS NO | 4318 |
| UNIPROT ACCESS NO | P14780 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This neutrophilic granule protein is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000058 |
| MONCLONAL ANTIBODY | Anti-MMP9 [EP1254] for Rat/Human |
Record No:123
| ACCESS NO | 101732 |
| GENE | MASP2 (MASP-2) |
| DESCRIPTION | Mannan-binding lectin serine peptidase 2 |
| NCBI ENTREZ ACCESS NO | 10747 |
| UNIPROT ACCESS NO | O00187 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protease is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0004630 |
| MONCLONAL ANTIBODY | N/A |
Record No:124
| ACCESS NO | 101763 |
| GENE | MBL2 |
| DESCRIPTION | Mannose-binding lectin |
| NCBI ENTREZ ACCESS NO | 4153 |
| UNIPROT ACCESS NO | P11226 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This local matrix protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0004482 |
| MONCLONAL ANTIBODY | Anti-Mannan Binding Lectin [3B6] for Human |
Record No:125
| ACCESS NO | 101800 |
| GENE | MB |
| DESCRIPTION | Myoglobin |
| NCBI ENTREZ ACCESS NO | 4151 |
| UNIPROT ACCESS NO | P02144 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This serum protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0004467 |
| MONCLONAL ANTIBODY | N/A |
Record No:126
| ACCESS NO | 101823 |
| GENE | MNDA |
| DESCRIPTION | Myeloid cell nuclear differentiation antigen |
| NCBI ENTREZ ACCESS NO | 4332 |
| UNIPROT ACCESS NO | P41218 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:127
| ACCESS NO | 101893 |
| GENE | MSN |
| DESCRIPTION | Moesin |
| NCBI ENTREZ ACCESS NO | 4478 |
| UNIPROT ACCESS NO | P26038 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Fibroblast |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is down regulated in atopic fibroblasts comparative to normal fibroblasts. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15468290 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Moesin for Human |
Record No:128
| ACCESS NO | 101936 |
| GENE | MAD2L2 |
| DESCRIPTION | Mitotic spindle assembly checkpoint protein |
| NCBI ENTREZ ACCESS NO | 10459 |
| UNIPROT ACCESS NO | Q9UI95 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mad2L2 for Mouse/Rat/Human |
Record No:129
| ACCESS NO | 101977 |
| GENE | MFI2 |
| DESCRIPTION | Melanotransferrin |
| NCBI ENTREZ ACCESS NO | 4241 |
| UNIPROT ACCESS NO | |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Expressed in patients with allergic rhinitis with or without asthma in upper airways. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:130
| ACCESS NO | 101985 |
| GENE | MYO5A |
| DESCRIPTION | Myosin VA |
| NCBI ENTREZ ACCESS NO | 17918 |
| UNIPROT ACCESS NO | Q99104 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in patients with allergic rhinitis with or without asthma in the upper airways. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:131
| ACCESS NO | 101998 |
| GENE | MB |
| DESCRIPTION | Myoglobin |
| NCBI ENTREZ ACCESS NO | 4151 |
| UNIPROT ACCESS NO | P02144 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in lower airways in patients suffering from allergic rhinitis with or without asthma. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | BE0004467 |
| MONCLONAL ANTIBODY | Anti-Myoglobin for Mouse/Rat/Human |
Record No:132
| ACCESS NO | 101999 |
| GENE | MAMDC2 |
| DESCRIPTION | MAM domain containing 2 |
| NCBI ENTREZ ACCESS NO | 256691 |
| UNIPROT ACCESS NO | Q7Z304 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in lower airways in patients suffering from allergic rhinitis with or without asthma. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:133
| ACCESS NO | 102002 |
| GENE | MPPE1 |
| DESCRIPTION | Metallophosphoesterase 1 |
| NCBI ENTREZ ACCESS NO | 65258 |
| UNIPROT ACCESS NO | Q53F39 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in lower airways in patients suffering from allergic rhinitis with or without asthma. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:134
| ACCESS NO | 102015 |
| GENE | MYLK |
| DESCRIPTION | Myosin light chain kinase |
| NCBI ENTREZ ACCESS NO | 4638 |
| UNIPROT ACCESS NO | Q15746 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in the lower airways in patients with allergic rhinitis and allergic asthma. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MYLK2 for Human |
Record No:135
| ACCESS NO | 102106 |
| GENE | MAL |
| DESCRIPTION | Mal T cell differentiation protein |
| NCBI ENTREZ ACCESS NO | 4118 |
| UNIPROT ACCESS NO | P21145 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthma. Involved in the TCR pathway. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:136
| ACCESS NO | 102130 |
| GENE | MEOX1 |
| DESCRIPTION | Mesenchyme homeobox 1 |
| NCBI ENTREZ ACCESS NO | 4222 |
| UNIPROT ACCESS NO | P50221 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in asthma.Involved in beta catenin/wnt signalling pathway. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:137
| ACCESS NO | 102140 |
| GENE | MUC2 |
| DESCRIPTION | Mucin 2 oligomeric |
| NCBI ENTREZ ACCESS NO | 4583 |
| UNIPROT ACCESS NO | Q02817 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Bronchial Biopsy |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergic asthma. Involved in mucus production. |
| GEO_PRIDE_ACCESS_NO | GSE41649 |
| REFERENCE | 19842841 |
| DRUG TARGET | BE0001034 |
| MONCLONAL ANTIBODY | Anti-MUC2 for Rat/Human |
Record No:138
| ACCESS NO | 102141 |
| GENE | MUC5AC |
| DESCRIPTION | Mucin 5AC |
| NCBI ENTREZ ACCESS NO | 4586 |
| UNIPROT ACCESS NO | P98088 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Bronchial Biopsy |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergic asthma. Involved in mucus production. |
| GEO_PRIDE_ACCESS_NO | GSE41649 |
| REFERENCE | 19842841 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mucin 5AC for Mouse/Human |