BROWSE RESULT OF N

61 Records

 

Record No:1


ACCESS NO100077
GENENLRC4 (CARD12)
DESCRIPTIONNLR family - CARD domain containing 4
NCBI ENTREZ ACCESS NO58484
UNIPROT ACCESS NOQ9NPP4
ORGANISMHuman
DISEASE PHENOTYPEAcute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESMicroarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is involved in innate immunity.
GEO_PRIDE_ACCESS_NOGSE16032
REFERENCE19620293
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:2


ACCESS NO100182
GENENAMPT (PBEF1)
DESCRIPTIONPre-B-cell colony enhancing factor 1
NCBI ENTREZ ACCESS NO10135
UNIPROT ACCESS NOP43490
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis is a immunity and defense related protein significantly up regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGETBE0002413
MONCLONAL ANTIBODYN/A


Record No:3


ACCESS NO100219
GENENID2
DESCRIPTIONNidogen 2
NCBI ENTREZ ACCESS NO22795
UNIPROT ACCESS NOQ14112
ORGANISMHuman
DISEASE PHENOTYPEAsthma and effect of house dust mite allergens on human airway epithelial cell
SAMPLEHuman airway epithelial cell
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSThis gene codes for a calcium binding protein significantly up regulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17919147
DRUG TARGET
MONCLONAL ANTIBODYAnti-Nidogen 2 for Human


Record No:4


ACCESS NO100258
GENENFKBIZ
DESCRIPTIONNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-zeta
NCBI ENTREZ ACCESS NO64332
UNIPROT ACCESS NOQ9BYH8
ORGANISMHuman
DISEASE PHENOTYPEAsthma exacerbation after rhinovirus infection
SAMPLEPrimary bronchial epithelial cells
TECHNIQUESAffymetrix GeneChip Microarray and qRT-PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt is a regulatory gene upregulated in asthma.
GEO_PRIDE_ACCESS_NOGSE13396
REFERENCE19710636
DRUG TARGET
MONCLONAL ANTIBODYAnti-IKB zeta for Human


Record No:5


ACCESS NO100302
GENENfatc3 (NFATX)
DESCRIPTIONNuclear factor of activated T-cells- cytoplasmic 3
NCBI ENTREZ ACCESS NO18021
UNIPROT ACCESS NOP97305
ORGANISMMouse
DISEASE PHENOTYPEAsthma induced by Aspergillus fumigatus allergens
SAMPLEPeripheral blood monocytes
TECHNIQUESDNA Microarray
OMICSGenomics
STUDY High Throughput
COMMENTSThis protein is involved in Cytokine signaling. It has been observed to be down regulated in the present study.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20840155
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:6


ACCESS NO100321
GENENr4a1
DESCRIPTIONNuclear receptor subfamily 4-group a-member 1
NCBI ENTREZ ACCESS NO79240
UNIPROT ACCESS NOP22829
ORGANISMRat
DISEASE PHENOTYPEEarly airway response (EAR) phase of asthma
SAMPLELung tissue
TECHNIQUESSerial analysis of gene expression (SAGE)
OMICSGenomics
STUDY High Throughput
COMMENTSIt s a component of MAPK signalling pathway.
GEO_PRIDE_ACCESS_NOGSE2475
REFERENCE18922145
DRUG TARGET
MONCLONAL ANTIBODYAnti-NUR77 for Mouse/Rat/Human


Record No:7


ACCESS NO100349
GENENFIX
DESCRIPTIONNuclear factor I/X
NCBI ENTREZ ACCESS NO4784
UNIPROT ACCESS NOQ14938
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESIllumina Human Ref8 BeadChip arrays
OMICSGenomics
STUDY High Throughput
COMMENTSIt is upregulated in asthma exacerbation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19187333
DRUG TARGET
MONCLONAL ANTIBODYAnti-NFIX for Human


Record No:8


ACCESS NO100417
GENENPM1
DESCRIPTIONNucleophosmin 1
NCBI ENTREZ ACCESS NO4869
UNIPROT ACCESS NOP06748
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEbronchial epithelial cells stimulated with TGF bet
TECHNIQUES2D PAGE and MALDI-TOF-MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in asthma inflammation. It is thought to control cell proliferation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20219718
DRUG TARGET
MONCLONAL ANTIBODYAnti-Nucleophosmin for Human


Record No:9


ACCESS NO100422
GENENME1
DESCRIPTIONNucleoside diphosphate kinase A
NCBI ENTREZ ACCESS NO4830
UNIPROT ACCESS NOP15531
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEbronchial epithelial cells stimulated with TGF bet
TECHNIQUES2D PAGE and MALDI-TOF-MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in asthma inflammation. It is thought to control cell proliferation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20219718
DRUG TARGETBE0003106
MONCLONAL ANTIBODYAnti-Nm23A for Human


Record No:10


ACCESS NO100454
GENENTS
DESCRIPTIONNeurotensin
NCBI ENTREZ ACCESS NO4922
UNIPROT ACCESS NOP30990
ORGANISMHuman
DISEASE PHENOTYPERespiratory Allergy
SAMPLENasal Epithelial Cell
TECHNIQUESAffymetrix microarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt has been implicated in wound healing.
GEO_PRIDE_ACCESS_NOGSE19190
REFERENCE22005912
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:11


ACCESS NO100476
GENENR4A3
DESCRIPTIONNuclear receptor subfamily 4 group A- member 3
NCBI ENTREZ ACCESS NO8013
UNIPROT ACCESS NOQ92570
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEAirway smooth muscle cell (ASM) line
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt has been implicated in smooth muscle biology but have not been studied in ASM or asthma. In this study it has been downregulated in ASM after dexamethasone treatment. Thus this transciption factor strong can be a candidate to modulate ASM phenotype.
GEO_PRIDE_ACCESS_NOGSE3946
REFERENCE21257922
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:12


ACCESS NO100548
GENENos2a
DESCRIPTIONNitric oxide synthase 2-inducible
NCBI ENTREZ ACCESS NO18126
UNIPROT ACCESS NOP29477
ORGANISMMouse
DISEASE PHENOTYPEAsthma
SAMPLETissue from bronchial biopsy
TECHNIQUESMicroarray-Affymetrix HG-U95Av2 GeneChips
OMICSGenomics
STUDY High Throughput
COMMENTSResponsible in immune signalling.
GEO_PRIDE_ACCESS_NOGSE15823
REFERENCE15038835
DRUG TARGETBE0000005
MONCLONAL ANTIBODYAnti-iNOS for Mouse/Rat


Record No:13


ACCESS NO100559
GENENkg7
DESCRIPTIONNatural killer cell group 7 sequence
NCBI ENTREZ ACCESS NO72310
UNIPROT ACCESS NOQ9CY55
ORGANISMMouse
DISEASE PHENOTYPEAsthma
SAMPLETissue from bronchial biopsy
TECHNIQUESMicroarray-Affymetrix HG-U95Av2 GeneChips
OMICSGenomics
STUDY High Throughput
COMMENTSmodultes natural killer cell for development of eosinophilia (data collected from supplementary table)
GEO_PRIDE_ACCESS_NOGSE15823
REFERENCE15038835
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:14


ACCESS NO100566
GENENME9
DESCRIPTIONThioredoxin-like 2
NCBI ENTREZ ACCESS NO347736
UNIPROT ACCESS NOQ86XW9
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLECD3+T cell
TECHNIQUES2D PAGE and MALDI-TOF-MS; real-time PCR
OMICSProteomics
STUDY High Throughput and Low Throughput
COMMENTSUpregulated in T lymphocytes of asthmatic patients.
GEO_PRIDE_ACCESS_NON/A
REFERENCE17550934
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:15


ACCESS NO100611
GENENOS2
DESCRIPTIONnitric oxide synthase 2
NCBI ENTREZ ACCESS NO4843
UNIPROT ACCESS NOP35228
ORGANISMHuman
DISEASE PHENOTYPEChildhood asthma
SAMPLEBuccal-cell suspension
TECHNIQUESBisulphite-specific PCR and pyrosequencing
OMICSEpigenetics
STUDY Low Throughput
COMMENTSSeveral CPG loci in NOS genes are methylated suggesting alteration in expression.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22591701
DRUG TARGETBE0000005
MONCLONAL ANTIBODYAnti-iNOS for Mouse/Rat


Record No:16


ACCESS NO100673
GENENp
DESCRIPTIONPurine nucleoside phosphorylase
NCBI ENTREZ ACCESS NO18950
UNIPROT ACCESS NOP23492
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAsthma induced by Ovalbumin
SAMPLELung tissue
TECHNIQUESMALDI Tof
OMICSProteomics
STUDY High Throughput
COMMENTSDownregulated in chronic asthma model.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21751807
DRUG TARGETBE0000250
MONCLONAL ANTIBODYAnti-Nucleoside phosphorylase for Human


Record No:17


ACCESS NO100742
GENENOX5
DESCRIPTIONNADPH oxidase EF-hand calcium binding domain 5
NCBI ENTREZ ACCESS NO79400
UNIPROT ACCESS NOQ96PH1
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEPerpheral blood mononuclear cells
TECHNIQUESMicroarray (agilent)
OMICSGenomics
STUDY High Throughput
COMMENTSIncreased in asthma patients and predicted to be a marker of mild asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21966607
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:18


ACCESS NO100767
GENENrp1
DESCRIPTIONNeuropilin-1
NCBI ENTREZ ACCESS NO18186
UNIPROT ACCESS NOP97333
ORGANISMbalb C mice
DISEASE PHENOTYPEAllergic asthma after challenge with Aspergillus fumigatus
SAMPLEPeriferal blood monocytes
TECHNIQUESMicroarray (agilent)
OMICSGenomics
STUDY High Throughput
COMMENTSInvolved in immune cell trafficking and cell movement.Selected based on fold change.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20840155
DRUG TARGETBE0002129
MONCLONAL ANTIBODYAnti-Neuropilin 1


Record No:19


ACCESS NO100776
GENENPPA
DESCRIPTIONNatriuretic peptide A
NCBI ENTREZ ACCESS NO4878
UNIPROT ACCESS NOP01160
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEDNA
TECHNIQUESIllumina Human Hap 550Kv3 BeadChip SNP array
OMICSGenomics
STUDY High Throughput
COMMENTSrs5065 SNP is a risk allele in this gene.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19264973
DRUG TARGETBE0002426
MONCLONAL ANTIBODYAnti-ANP for Human


Record No:20


ACCESS NO100811
GENENcapg
DESCRIPTIONNon SMC comdensin 1 complex
NCBI ENTREZ ACCESS NO54392
UNIPROT ACCESS NOE9PWG6
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAcute and chronic asthma
SAMPLELung Tissue
TECHNIQUESGeneChip Expression 3 (affymetrix) microarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in short time allergen exposure and downregulated in long exposure.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19028979
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:21


ACCESS NO100812
GENENusap1
DESCRIPTIONNucleolar and spindle associated protein 1
NCBI ENTREZ ACCESS NO108907
UNIPROT ACCESS NOQ9ERH4
ORGANISMBALB/c Mouse
DISEASE PHENOTYPEAcute and chronic asthma
SAMPLELung Tissue
TECHNIQUESGeneChip Expression 3 (affymetrix) microarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in short time allergen exposure and downregulated in long exposure.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19028979
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:22


ACCESS NO100953
GENENPSR1
DESCRIPTIONNeuropeptide S receptor 1
NCBI ENTREZ ACCESS NO387129
UNIPROT ACCESS NOQ6W5P4
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis
SAMPLEGenomic DNA from buccal cells
TECHNIQUESIllumina HumanHap 550 k BeadChip version 3
OMICSGenomics
STUDY High Throughput
COMMENTSPolymorphisms in this gene has been linked to asthma. Identified as potential susceptibility gene for allergic rhinitis.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23663310
DRUG TARGETBE0000948
MONCLONAL ANTIBODYAnti-NPSR1 for Human


Record No:23


ACCESS NO101015
GENENFKB2
DESCRIPTIONNuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NCBI ENTREZ ACCESS NO4791
UNIPROT ACCESS NOQ00653
ORGANISMHuman
DISEASE PHENOTYPEAsthma with eosinophilic and neutrophilic inflammation
SAMPLESputum
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt shows highest expression in patients with neutrophilic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24582314
DRUG TARGETBE0002387
MONCLONAL ANTIBODYN/A


Record No:24


ACCESS NO101016
GENENFKBIZ
DESCRIPTIONNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor zeta
NCBI ENTREZ ACCESS NO64332
UNIPROT ACCESS NOQ9BYH8
ORGANISMHuman
DISEASE PHENOTYPEAsthma with eosinophilic and neutrophilic inflammation
SAMPLESputum
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt shows highest expression in patients with neutrophilic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24582314
DRUG TARGET
MONCLONAL ANTIBODYAnti-IKB zeta for Human


Record No:25


ACCESS NO101017
GENENLRP3
DESCRIPTIONNLR family - pyrin domain containing 3
NCBI ENTREZ ACCESS NO114548
UNIPROT ACCESS NOQ96P20
ORGANISMHuman
DISEASE PHENOTYPEAsthma with eosinophilic and neutrophilic inflammation
SAMPLESputum
TECHNIQUESMicroarray and qPCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSIt shows highest expression in patients with neutrophilic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE24582314
DRUG TARGET
MONCLONAL ANTIBODYAnti-CIAS1 / NALP3 for Human


Record No:26


ACCESS NO101138
GENENOS2
DESCRIPTIONInducible nitric oxide synthase 2
NCBI ENTREZ ACCESS NO4843
UNIPROT ACCESS NOP35228
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLESerum
TECHNIQUESImmunoassay
OMICSOthers
STUDY Low Throughput
COMMENTSBronchial epithelial expression levels of this gene correlated with bronchial IL-13 and IL-5 expression. We observed relatively strong positive correlations between bronchial or systemic eosinophilia and serum periostin levels.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22857879
DRUG TARGETBE0000005
MONCLONAL ANTIBODYAnti-iNOS for Mouse/Human


Record No:27


ACCESS NO101142
GENENR3C1 (GCRα)
DESCRIPTIONGlucocorticoid receptor alpha
NCBI ENTREZ ACCESS NO2908
UNIPROT ACCESS NOP04150
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEPeripheral blood mononuclear cells
TECHNIQUESreal-time PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSReduced expression of this dominant functional alpha isoform of the GCR may mediate glucocorticoid insensitivity in obese asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE22606276
DRUG TARGETBE0000794
MONCLONAL ANTIBODYN/A


Record No:28


ACCESS NO101248
GENENos2
DESCRIPTIONInducible nitric oxide synthase 2
NCBI ENTREZ ACCESS NO18126
UNIPROT ACCESS NOP29477
ORGANISMMouse
DISEASE PHENOTYPEAsthma and effct of the drug 'Artesunate'
SAMPLELung tissue
TECHNIQUESreal time PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSPretreatment with artesunate (30 mg/kg) demonstrated strong suppression of this gene the enzyme responsible for nitric oxide (NO) production in allergic airway inflammation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21695271
DRUG TARGETBE0000005
MONCLONAL ANTIBODYAnti-iNOS for Mouse/Human


Record No:29


ACCESS NO101407
GENENoxo1
DESCRIPTIONNADPH oxidase organizer 1
NCBI ENTREZ ACCESS NO71893
UNIPROT ACCESS NOQ8VCM2
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSOverexpressed after 3hours and 12 hours of allergenic mould extract challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGETBE0002423
MONCLONAL ANTIBODYN/A


Record No:30


ACCESS NO101452
GENENfkb2
DESCRIPTIONNuclear factor of kappa light polypeptide gene enhancer in B cells 2
NCBI ENTREZ ACCESS NO18034
UNIPROT ACCESS NOQ9WTK5
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSMultifunction transcription factor. Given lower priority in manual annotation.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGETBE0002387
MONCLONAL ANTIBODYAnti-NFkB p100 / p52 for Mouse/Rat/Human


Record No:31


ACCESS NO101465
GENENcf4
DESCRIPTIONNeutrophil cytosolic factor 4
NCBI ENTREZ ACCESS NO17972
UNIPROT ACCESS NOP97369
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSOverexpressed after 3hours and 12 hours of allergenic mould extract challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-NCF4 for Human


Record No:32


ACCESS NO101466
GENENr4a2
DESCRIPTIONNuclear receptor subfamily 4 group A member 2
NCBI ENTREZ ACCESS NO18227
UNIPROT ACCESS NOQ06219
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSOverexpressed after 3hours and 12 hours of allergenic mould extract challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-Nurr1 for Mouse/Rat/Human


Record No:33


ACCESS NO101470
GENENlrp3
DESCRIPTIONNLR family pyrin domain containing 3
NCBI ENTREZ ACCESS NO216799
UNIPROT ACCESS NOQ8R4B8
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSOverexpressed after 3hours and 12 hours of allergenic mould extract challenge.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:34


ACCESS NO101477
GENENfkbiz
DESCRIPTIONNuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor zeta
NCBI ENTREZ ACCESS NO80859
UNIPROT ACCESS NOQ9EST8
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3 and 12 hours of fungal allergen challenge in asthmatic mice.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-IKB zeta for Human


Record No:35


ACCESS NO101496
GENENek6
DESCRIPTIONNIMA (never in mitosis gene a)-related expressed kinase 6
NCBI ENTREZ ACCESS NO59126
UNIPROT ACCESS NOQ9ES70
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3 and 12 hours of allergen induction in asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-NEK6 for Mouse/Rat/Human


Record No:36


ACCESS NO101511
GENENfkbie
DESCRIPTIONNuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor
NCBI ENTREZ ACCESS NO18037
UNIPROT ACCESS NOO54910
ORGANISMFemale BALB/c mice
DISEASE PHENOTYPEAllergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar
SAMPLELung Tissue
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated after 3 and 12 hours of allergen induction in asthmatics.
GEO_PRIDE_ACCESS_NON/A
REFERENCE20045013
DRUG TARGET
MONCLONAL ANTIBODYAnti-IKB epsilon for Human


Record No:37


ACCESS NO101627
GENENcor2
DESCRIPTIONNuclear receptor co-repressor 2
NCBI ENTREZ ACCESS NO20602
UNIPROT ACCESS NOQ9WU42
ORGANISMBalb/C wild-type mice
DISEASE PHENOTYPEAllergic asthma induced by both Ovalbumin and mIL-13
SAMPLELung tissue
TECHNIQUESGene Chip microarray
OMICSGenomics
STUDY High Throughput
COMMENTSExpressed after IL 13 induction.
GEO_PRIDE_ACCESS_NON/A
REFERENCE16402082
DRUG TARGET
MONCLONAL ANTIBODYAnti-NCOR2 for Human


Record No:38


ACCESS NO101669
GENENfkb1 (NF- kappa B)
DESCRIPTIONNuclear factor of kappa light polypeptide gene enhancer in B cells 1
NCBI ENTREZ ACCESS NO18033
UNIPROT ACCESS NOP25799
ORGANISMMouse
DISEASE PHENOTYPEAsthma and its modulation by Minocycline
SAMPLELung cells
TECHNIQUESImmunoblot and immunflorescence
OMICSProteomics
STUDY Low Throughput
COMMENTSMinocycline may inhibit NF Kappa Beta activation in response to more than one stimulus and that such inhibition appeared to reside at the phosphorylation level of the protein.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23184953
DRUG TARGETBE0001086
MONCLONAL ANTIBODYN/A


Record No:39


ACCESS NO101672
GENENos2 (iNOS)
DESCRIPTIONInducible nitric oxide synthase 2
NCBI ENTREZ ACCESS NO18126
UNIPROT ACCESS NOP29477
ORGANISMMouse
DISEASE PHENOTYPEAsthma and its modulation by Minocycline
SAMPLELung cells
TECHNIQUESReal time PCR
OMICSGenomics
STUDY Low Throughput
COMMENTSMinocycline marked reduction in the expression of this NF kappa Beta dependent gene.
GEO_PRIDE_ACCESS_NON/A
REFERENCE23184953
DRUG TARGETBE0000005
MONCLONAL ANTIBODYAnti-iNOS [4E5] for Mouse/Human


Record No:40


ACCESS NO101677
GENENFKBIA (IKBA)
DESCRIPTIONNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor - alpha
NCBI ENTREZ ACCESS NO4792
UNIPROT ACCESS NOP25963
ORGANISMMouse
DISEASE PHENOTYPEAsthma and its protection by IGFBP-3 treatment
SAMPLELung tissue and Broncho Alveolar Lavage (BAL) flui
TECHNIQUESImmunoblot
OMICSProteomics
STUDY Low Throughput
COMMENTSIGFBP-3 degrades I kappa beta alpha through IGFBP-3 receptor (IGFBP-3R)-mediated activation of caspases thereby inhibiting TNF- -induced activation of NF- B signaling cascades.
GEO_PRIDE_ACCESS_NON/A
REFERENCE21383009
DRUG TARGETBE0003469
MONCLONAL ANTIBODYAnti-IKB alpha [6A920] for Mouse/Rat/Human


Record No:41


ACCESS NO101684
GENENPS
DESCRIPTIONNeuropeptide S
NCBI ENTREZ ACCESS NO594857
UNIPROT ACCESS NOP0C0P6
ORGANISMHuman
DISEASE PHENOTYPEAsthma
SAMPLEChinese hamster ovary (CHO) or HEK 293 T cells
TECHNIQUESMolecular clonng (recobinant expression and mutage
OMICSGenomics
STUDY Low Throughput
COMMENTSN107I mutational variant of NPSR interacts with the NH2-terminal third and part of a nascent helix within NPS causing an increase in cell-surface expression of the mutant receptor. This missense mutation results in an increase in the potency of NPS for NPSR that is pathophysiologically associated with an increased prevalance of asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE16790440
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:42


ACCESS NO101741
GENENME2
DESCRIPTIONNucleoside-diphosphate kinase B
NCBI ENTREZ ACCESS NO4831
UNIPROT ACCESS NOJ3KPD9
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0003281
MONCLONAL ANTIBODYAnti-NME2 for Mouse/Rat/Human


Record No:43


ACCESS NO101746
GENENAGK
DESCRIPTIONN-Acetylglucosamine kinase (GlcNAc kinase)
NCBI ENTREZ ACCESS NO55577
UNIPROT ACCESS NOH0YC94
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is up regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0002265
MONCLONAL ANTIBODYAnti-N acetylglucosamine kinase [AT4D12] for Human


Record No:44


ACCESS NO101835
GENENTM
DESCRIPTIONNeurotrimin precursor
NCBI ENTREZ ACCESS NO50863
UNIPROT ACCESS NOQ9P121
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is down regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:45


ACCESS NO101837
GENENRP1
DESCRIPTIONNeuropilin 1
NCBI ENTREZ ACCESS NO8829
UNIPROT ACCESS NOO14786
ORGANISMHuman
DISEASE PHENOTYPEAsthma induced by allergen challenge
SAMPLEBroncho Alveolar Lavage (BAL) Fluid
TECHNIQUESLC-MS/MS
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is down regulated in allergic asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15951573
DRUG TARGETBE0002129
MONCLONAL ANTIBODYAnti-Neuropilin 1 [EPR3113] for Mouse/Rat/Human


Record No:46


ACCESS NO101879
GENENAGK
DESCRIPTIONN-acetylglucosamine kinase
NCBI ENTREZ ACCESS NO55577
UNIPROT ACCESS NOQ9UJ70
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEFibroblast
TECHNIQUES2D-PAGE and MALDI-TOF/TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic fibroblasts comparative to normal fibroblasts.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15468290
DRUG TARGETBE0002265
MONCLONAL ANTIBODYAnti-N acetylglucosamine kinase for Human


Record No:47


ACCESS NO101891
GENENR1H4
DESCRIPTIONBile acid receptor
NCBI ENTREZ ACCESS NO9971
UNIPROT ACCESS NOQ96RI1
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEFibroblast
TECHNIQUES2D-PAGE and MALDI-TOF/TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is down regulated in atopic fibroblasts comparative to normal fibroblasts.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15468290
DRUG TARGETBE0001777
MONCLONAL ANTIBODYAnti-Bile Acid Receptor NR1H4 for Human


Record No:48


ACCESS NO101895
GENENOS3
DESCRIPTIONNitric oxide synthase (NOS type III)
NCBI ENTREZ ACCESS NO4846
UNIPROT ACCESS NOP29474
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPeripheral blood eosinophils
TECHNIQUES2DE-PAGE and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic dermatitis patients eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15832365
DRUG TARGETBE0000263
MONCLONAL ANTIBODYAnti-NOS for Mouse/Rat/Human


Record No:49


ACCESS NO101907
GENENR2F1
DESCRIPTIONCOUP transcription factor 1
NCBI ENTREZ ACCESS NO7025
UNIPROT ACCESS NOP10589
ORGANISMHuman
DISEASE PHENOTYPEAtopic dermatitis
SAMPLEPeripheral blood eosinophils
TECHNIQUES2DE-PAGE and MALDI-TOF
OMICSProteomics
STUDY High Throughput
COMMENTSThis protein is upregulated in atopic dermatitis patients eosinophils.
GEO_PRIDE_ACCESS_NON/A
REFERENCE15832365
DRUG TARGET
MONCLONAL ANTIBODYAnti-COUP TF1 for Mouse/Rat/Human


Record No:50


ACCESS NO101946
GENENFIX
DESCRIPTIONNuclear factor I/X
NCBI ENTREZ ACCESS NO4784
UNIPROT ACCESS NOB4DHW2
ORGANISMHuman(Asthmatic children)
DISEASE PHENOTYPEAsthma( Mite sensitized asthma)
SAMPLEPeripheral Blood Mononuclear Cells
TECHNIQUESMicroarray and RT-PCR
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in asthma.
GEO_PRIDE_ACCESS_NON/A
REFERENCE19187333
DRUG TARGET
MONCLONAL ANTIBODYAnti-NFIX for Human


Record No:51


ACCESS NO101975
GENENME7
DESCRIPTIONNME/NM23 family member 7
NCBI ENTREZ ACCESS NO29922
UNIPROT ACCESS NOQ9Y5B8
ORGANISMHuman
DISEASE PHENOTYPEAsthma and allergic rhinitis
SAMPLEEpithelial cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSExpressed in patients with allergic rhinitis with or without asthma in upper airways.
GEO_PRIDE_ACCESS_NOGSE51392
REFERENCE24475887
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:52


ACCESS NO101979
GENENSD1
DESCRIPTIONNuclear receptor binding SET domain protein 1
NCBI ENTREZ ACCESS NO64324
UNIPROT ACCESS NOQ96L73
ORGANISMHuman
DISEASE PHENOTYPEAsthma and allergic rhinitis
SAMPLEEpithelial cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSExpressed in patients with allergic rhinitis with or without asthma in upper airways.
GEO_PRIDE_ACCESS_NOGSE51392
REFERENCE24475887
DRUG TARGET
MONCLONAL ANTIBODYAnti-KMT3B / NSD1 for Human


Record No:53


ACCESS NO101984
GENENEBL
DESCRIPTIONNebulette
NCBI ENTREZ ACCESS NO10529
UNIPROT ACCESS NOO76041
ORGANISMHuman
DISEASE PHENOTYPEAsthma and allergic rhinitis
SAMPLEEpithelial cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDownregulated in patients with allergic rhinitis with or without asthma in the upper airways.
GEO_PRIDE_ACCESS_NOGSE51392
REFERENCE24475887
DRUG TARGET
MONCLONAL ANTIBODYAnti-TAZ for Human


Record No:54


ACCESS NO102007
GENENPFFR2
DESCRIPTIONNeuropeptide FF receptor 2
NCBI ENTREZ ACCESS NO10886
UNIPROT ACCESS NOQ9Y5X5
ORGANISMHuman
DISEASE PHENOTYPEAsthma and allergic rhinitis
SAMPLEEpithelial cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in the lower airways in patients with allergic rhinitis.
GEO_PRIDE_ACCESS_NOGSE51392
REFERENCE24475887
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:55


ACCESS NO102036
GENENCF2
DESCRIPTIONNeutrophil cytosolic factor 2
NCBI ENTREZ ACCESS NO4688
UNIPROT ACCESS NOP19878
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis and asthma
SAMPLEBronchial epithelial cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput
COMMENTSHighly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table).
GEO_PRIDE_ACCESS_NOGSE44037
REFERENCE24282527
DRUG TARGETBE0002423
MONCLONAL ANTIBODYN/A


Record No:56


ACCESS NO102037
GENENLRP1
DESCRIPTIONNLR family pyrin domain containing 1
NCBI ENTREZ ACCESS NO22861
UNIPROT ACCESS NOQ9C000
ORGANISMHuman
DISEASE PHENOTYPEAllergic rhinitis and asthma
SAMPLEBronchial epithelial cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput
COMMENTSHighly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table).
GEO_PRIDE_ACCESS_NOGSE44037
REFERENCE24282527
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:57


ACCESS NO102091
GENENCOA3
DESCRIPTIONNuclear receptor coactivator 3
NCBI ENTREZ ACCESS NO8202
UNIPROT ACCESS NOQ59EE8
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSDifferentially expressed in asthma. Promtes STAT6 signalling.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYAnti-NCOA3 for Human


Record No:58


ACCESS NO102092
GENENDFIP2
DESCRIPTIONNedd4 family-interacting protein 2
NCBI ENTREZ ACCESS NO54602
UNIPROT ACCESS NOQ9NV92
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray and real time PCR
OMICSGenomics
STUDY High Throughput and Low Throughput
COMMENTSActivated in asthma. Promotes IFN gamma production.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYN/A


Record No:59


ACCESS NO102093
GENENSMCE1
DESCRIPTIONNon-SMC element 1 homolog
NCBI ENTREZ ACCESS NO197370
UNIPROT ACCESS NOQ8WV22
ORGANISMHuman
DISEASE PHENOTYPEAtopic asthma
SAMPLECD4+ T cells
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSActivated in asthma. Involved in signal transduction and expressed in TH2 cells.
GEO_PRIDE_ACCESS_NOGSE14908
REFERENCE19414752
DRUG TARGET
MONCLONAL ANTIBODYAnti-NSMCE1 for Mouse/Rat/Human


Record No:60


ACCESS NO102139
GENENOS2A
DESCRIPTIONNitric oxide synthase 2A
NCBI ENTREZ ACCESS NO4843
UNIPROT ACCESS NOP35228
ORGANISMHuman
DISEASE PHENOTYPEAllergic asthma
SAMPLEBronchial Biopsy
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in allergic asthma. It is an immune signalling molecule.
GEO_PRIDE_ACCESS_NOGSE41649
REFERENCE19842841
DRUG TARGETBE0000005
MONCLONAL ANTIBODYN/A


Record No:61


ACCESS NO102149
GENENQO1
DESCRIPTIONNAD(P)H dehydrogenase quinone 1
NCBI ENTREZ ACCESS NO1728
UNIPROT ACCESS NOP15559
ORGANISMHuman
DISEASE PHENOTYPEAllergic asthma
SAMPLEBronchial Biopsy
TECHNIQUESMicroarray
OMICSGenomics
STUDY High Throughput
COMMENTSUpregulated in allergic asthma.
GEO_PRIDE_ACCESS_NOGSE41649
REFERENCE19842841
DRUG TARGETBE0001184
MONCLONAL ANTIBODYAnti-NQO1 for Mouse/Rat/Human