BROWSE RESULT OF P
| 143 Records |
| ACCESS NO | 100000 |
| GENE | PSPH |
| DESCRIPTION | Phosphoserine phosphatase |
| NCBI ENTREZ ACCESS NO | 5723 |
| UNIPROT ACCESS NO | P78330 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in low SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | BE0004590 |
| MONCLONAL ANTIBODY | Anti-Phosphoserine phosphatase for Mouse/Human |
Record No:2
| ACCESS NO | 100005 |
| GENE | PPBP |
| DESCRIPTION | Pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| NCBI ENTREZ ACCESS NO | 5473 |
| UNIPROT ACCESS NO | P02775 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It regulates chemokine activity. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | BE0000946 |
| MONCLONAL ANTIBODY | N/A |
Record No:3
| ACCESS NO | 100013 |
| GENE | PF4 |
| DESCRIPTION | Platelet factor 4 |
| NCBI ENTREZ ACCESS NO | 5196 |
| UNIPROT ACCESS NO | P02776 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It participates in chemokine activity. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | BE0001129 |
| MONCLONAL ANTIBODY | Anti-PF4 for Rat/Human |
Record No:4
| ACCESS NO | 100026 |
| GENE | PCMTD2 |
| DESCRIPTION | Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
| NCBI ENTREZ ACCESS NO | 55251 |
| UNIPROT ACCESS NO | Q9NV79 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in low SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:5
| ACCESS NO | 100055 |
| GENE | PTGER2 |
| DESCRIPTION | Prostaglandin E receptor 2 (subtype EP2) |
| NCBI ENTREZ ACCESS NO | 5732 |
| UNIPROT ACCESS NO | P43116 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in arachidonic acid/prostagandin metabolism. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Prostaglandin E Receptor EP2 for Rat/Human |
Record No:6
| ACCESS NO | 100056 |
| GENE | PECAM1 |
| DESCRIPTION | Platelet/endothelial cell adhesion molecule 1 |
| NCBI ENTREZ ACCESS NO | 5175 |
| UNIPROT ACCESS NO | P16284 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in leukocyte migration |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD31 [P2B1] for Mouse/Rat/Human |
Record No:7
| ACCESS NO | 100062 |
| GENE | PF4V1 |
| DESCRIPTION | Platelet factor 4 variant 1 |
| NCBI ENTREZ ACCESS NO | 5197 |
| UNIPROT ACCESS NO | P10720 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in leukocyte migration |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:8
| ACCESS NO | 100166 |
| GENE | PARK7 |
| DESCRIPTION | Parkinson disease 7 |
| NCBI ENTREZ ACCESS NO | 11315 |
| UNIPROT ACCESS NO | Q99497 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | BE0000992 |
| MONCLONAL ANTIBODY | Anti-PARK7/DJ1 [malphaDJ-1/E2.19] for Human |
Record No:9
| ACCESS NO | 100180 |
| GENE | PPP2R2B |
| DESCRIPTION | Protein phosphatase 2 - regulatory subunit B - beta isoform |
| NCBI ENTREZ ACCESS NO | 5521 |
| UNIPROT ACCESS NO | Q00005 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PPP2R2B for Mouse/Rat/Human |
Record No:10
| ACCESS NO | 100181 |
| GENE | PTX3 |
| DESCRIPTION | Pentraxin 3 |
| NCBI ENTREZ ACCESS NO | 5806 |
| UNIPROT ACCESS NO | P26022 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This is a immunity and defense related protein significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PITX3 for Mouse/Rat/Human |
Record No:11
| ACCESS NO | 100188 |
| GENE | PTPRB |
| DESCRIPTION | Protein tyrosine phosphatase receptor type B |
| NCBI ENTREZ ACCESS NO | 5787 |
| UNIPROT ACCESS NO | P23467 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a receptor protein significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | BE0003769 |
| MONCLONAL ANTIBODY | Anti-PTPRB for Rat |
Record No:12
| ACCESS NO | 100211 |
| GENE | PAPSS2 |
| DESCRIPTION | 3' - phosphoadenosine 5'- phosphosulfate synthase 2 |
| NCBI ENTREZ ACCESS NO | 9060 |
| UNIPROT ACCESS NO | O95340 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene codes for a metabolic enzyme significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PAPSS2 for Human |
Record No:13
| ACCESS NO | 100280 |
| GENE | PTPRE |
| DESCRIPTION | Protein tyrosine phosphatase-receptor type E |
| NCBI ENTREZ ACCESS NO | 5791 |
| UNIPROT ACCESS NO | P23469 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is upregulated in asthma exacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | BE0003568 |
| MONCLONAL ANTIBODY | Anti-PTP epsilon for Human |
Record No:14
| ACCESS NO | 100282 |
| GENE | PHLDA1 |
| DESCRIPTION | Pleckstrin homology-like domain family A-member 1 |
| NCBI ENTREZ ACCESS NO | 22822 |
| UNIPROT ACCESS NO | Q8WV24 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is upregulated in asthma exacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PHLDA for Human |
Record No:15
| ACCESS NO | 100337 |
| GENE | Prdx2 |
| DESCRIPTION | Peroxiredoxin 2 |
| NCBI ENTREZ ACCESS NO | 21672 |
| UNIPROT ACCESS NO | Q61171 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced chemicals |
| SAMPLE | Auricular Lymph Nodes |
| TECHNIQUES | 2D DIGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is mostly expressed at the site of inflammation and is also involved in the activation of T lymphocytes and the maturation of B cells. It is down regulated in this study. This downregulation is in agreement with the fact that a the deleion of the PrxII gene led to a proliferation of the spleen and an activation of T lymphocytes and dendritic cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20860378 |
| DRUG TARGET | BE0001972 |
| MONCLONAL ANTIBODY | Anti-Peroxiredoxin 2 [EPR5154] for Mouse/Rat/Human |
Record No:16
| ACCESS NO | 100351 |
| GENE | PRAM1 |
| DESCRIPTION | PML-RARA-regulated adaptor molecule 1 |
| NCBI ENTREZ ACCESS NO | 84106 |
| UNIPROT ACCESS NO | Q96QH2 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is upregulated in asthma exacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:17
| ACCESS NO | 100364 |
| GENE | Pm20d1 |
| DESCRIPTION | Unnamed protein product (Probable carboxypeptidase) |
| NCBI ENTREZ ACCESS NO | 212933 |
| UNIPROT ACCESS NO | Q8C165 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergen induced asthma and Dexamethasone treatment |
| SAMPLE | Broncho Alveolar Lavage (BAL) |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is downregulated after dexamethasoner treatment of asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15378748 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:18
| ACCESS NO | 100365 |
| GENE | Pdia3 |
| DESCRIPTION | Glucose regulated protein |
| NCBI ENTREZ ACCESS NO | 14827 |
| UNIPROT ACCESS NO | P27773 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergen induced asthma and Dexamethasone treatment |
| SAMPLE | Broncho Alveolar Lavage (BAL) |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It codes for cellular metabolism-related proteins. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15378748 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-ERp57 for Rat/Human/Mouse/Rabbit |
Record No:19
| ACCESS NO | 100371 |
| GENE | Plg |
| DESCRIPTION | Plasminogen |
| NCBI ENTREZ ACCESS NO | 18815 |
| UNIPROT ACCESS NO | P20918 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergen induced asthma and Dexamethasone treatment |
| SAMPLE | Broncho Alveolar Lavage (BAL) |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is converted to plasmin. Plasmin in turn activates Matrix Metallo-proteases directly to degrade ECM components or degrade ECM by inhibiting MMP inhibitors. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15378748 |
| DRUG TARGET | BE0000211 |
| MONCLONAL ANTIBODY | N/A |
Record No:20
| ACCESS NO | 100377 |
| GENE | Pigr |
| DESCRIPTION | Polymeric-immunoglobulin receptor |
| NCBI ENTREZ ACCESS NO | 18703 |
| UNIPROT ACCESS NO | O70570 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | 2D PAGE andLC-MS/MS followed by western blot and r |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This protein was found to be significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20029843 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PIGR [7C1] for Mouse/Human |
Record No:21
| ACCESS NO | 100384 |
| GENE | Plg |
| DESCRIPTION | Plasminogen |
| NCBI ENTREZ ACCESS NO | 18815 |
| UNIPROT ACCESS NO | P20918 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | 2D PAGE andLC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This gene is downregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20029843 |
| DRUG TARGET | BE0000211 |
| MONCLONAL ANTIBODY | N/A |
Record No:22
| ACCESS NO | 100396 |
| GENE | Pla2g4a |
| DESCRIPTION | cytosolic phospholipase A2 (cPLA2) |
| NCBI ENTREZ ACCESS NO | 18783 |
| UNIPROT ACCESS NO | P47713 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergen induced asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | Immunoblot |
| OMICS | Proteomics |
| STUDY | Low Throughput |
| COMMENTS | Allergen-induced oxidative stress results in proteolysis of annexin-1 and consequent up-regulation of cPLA2 activity and leukotriene production in this study. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15378764 |
| DRUG TARGET | BE0000657 |
| MONCLONAL ANTIBODY | Anti-Phospholipase A2 for Human |
Record No:23
| ACCESS NO | 100409 |
| GENE | PGC |
| DESCRIPTION | Pepsinogen C |
| NCBI ENTREZ ACCESS NO | 102124827 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Monkey |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA microarrays and Quantitative RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is significantly downregulated upon allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 12049661 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PGC1 alpha for Human |
Record No:24
| ACCESS NO | 100428 |
| GENE | PFDN2 |
| DESCRIPTION | Prefoldin subunit 2 |
| NCBI ENTREZ ACCESS NO | 5202 |
| UNIPROT ACCESS NO | Q9UHV9 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | bronchial epithelial cells stimulated with TGF bet |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is upregulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20219718 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:25
| ACCESS NO | 100453 |
| GENE | POSTN |
| DESCRIPTION | Periostin osteoblast-specific factor |
| NCBI ENTREZ ACCESS NO | 10631 |
| UNIPROT ACCESS NO | Q15063 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Respiratory Allergy |
| SAMPLE | Nasal Epithelial Cell |
| TECHNIQUES | Affymetrix microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is a Th2 signature gene. It is associated basal or mucous cells. It is also involved in cell cycle progression and tissue repair. |
| GEO_PRIDE_ACCESS_NO | GSE19190 |
| REFERENCE | 22005912 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Periostin for Human |
Record No:26
| ACCESS NO | 100462 |
| GENE | PLK4 |
| DESCRIPTION | Polo-like kinase 4 |
| NCBI ENTREZ ACCESS NO | 10733 |
| UNIPROT ACCESS NO | O00444 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Respiratory Allergy |
| SAMPLE | Nasal Epithelial Cell |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is induced during cell differentiation while being down-regulated in patients with uncontrolled asthma. It is an important marker of multiciliogenesis. |
| GEO_PRIDE_ACCESS_NO | GSE19190 |
| REFERENCE | 22005912 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PLK4 for Human |
Record No:27
| ACCESS NO | 100470 |
| GENE | PER1 |
| DESCRIPTION | Period circadian clock 1 |
| NCBI ENTREZ ACCESS NO | 5187 |
| UNIPROT ACCESS NO | O15534 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Airway smooth muscle cell (ASM) line |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is induced in airway smooth muscle cell after glucocorticoid treatment. |
| GEO_PRIDE_ACCESS_NO | GSE3946 |
| REFERENCE | 21257922 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PER1 for Human |
Record No:28
| ACCESS NO | 100471 |
| GENE | PIK3R1 |
| DESCRIPTION | Phosphoinositide-3-kinase regulatory subunit 1 |
| NCBI ENTREZ ACCESS NO | 5295 |
| UNIPROT ACCESS NO | P27986 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Airway smooth muscle cell (ASM) line |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is induced in airway smooth muscle cell after glucocorticoid treatment. |
| GEO_PRIDE_ACCESS_NO | GSE3946 |
| REFERENCE | 21257922 |
| DRUG TARGET | BE0000955 |
| MONCLONAL ANTIBODY | N/A |
Record No:29
| ACCESS NO | 100500 |
| GENE | PPIA |
| DESCRIPTION | Peptidylprolyl isomerase A (cyclophilin A) |
| NCBI ENTREZ ACCESS NO | 5478 |
| UNIPROT ACCESS NO | P62937 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of glucocorticoid treatment |
| SAMPLE | Bronchial biopsy |
| TECHNIQUES | iTRAQ labelling followed by nano LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in chemotaxix. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21939520 |
| DRUG TARGET | BE0001014 |
| MONCLONAL ANTIBODY | Anti-Cyclophilin A for Human |
Record No:30
| ACCESS NO | 100503 |
| GENE | POSTN |
| DESCRIPTION | Periostin |
| NCBI ENTREZ ACCESS NO | 10631 |
| UNIPROT ACCESS NO | Q15063 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and corticosteroids treatment |
| SAMPLE | Airway epithelial cells |
| TECHNIQUES | microarray-Affymetrix and q-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is an integrin ligand and extracellular matrix protein with roles in cell adhesion together with motility and matrix remodelling remodeling |
| GEO_PRIDE_ACCESS_NO | GSE4302 |
| REFERENCE | 17898169 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Periostin for Human |
Record No:31
| ACCESS NO | 100564 |
| GENE | PDE4C |
| DESCRIPTION | cAMP-specific 3'and 5'-cyclic phosphodiesterase 4C |
| NCBI ENTREZ ACCESS NO | 5143 |
| UNIPROT ACCESS NO | Q08493 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | CD3+T cell |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS; real-time PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in T lymphocytes of asthmatic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17550934 |
| DRUG TARGET | BE0002353 |
| MONCLONAL ANTIBODY | N/A |
Record No:32
| ACCESS NO | 100575 |
| GENE | Prdx6 |
| DESCRIPTION | Cys-Peroxiredoxin |
| NCBI ENTREZ ACCESS NO | 11758 |
| UNIPROT ACCESS NO | O08709 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic inflammation |
| SAMPLE | Bronchoalveolar lavage fluid |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Expressed in macrophages and functions as an antioxidant. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17082650 |
| DRUG TARGET | BE0004641 |
| MONCLONAL ANTIBODY | Anti-Peroxiredoxin 6 for Human/Mouse/Rat |
Record No:33
| ACCESS NO | 100583 |
| GENE | PLUNC |
| DESCRIPTION | BPI fold-containing family A member-PLUNC |
| NCBI ENTREZ ACCESS NO | 51297 |
| UNIPROT ACCESS NO | Q9NP55 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Seasonal allergic rhinitis |
| SAMPLE | Nasal Lavage Fluid |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | A novel innate imunity protein. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16457599 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PLUNC for Mouse/Rat/Human |
Record No:34
| ACCESS NO | 100595 |
| GENE | PON1 |
| DESCRIPTION | Paraoxonase 1 |
| NCBI ENTREZ ACCESS NO | 5444 |
| UNIPROT ACCESS NO | P27169 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000930 |
| MONCLONAL ANTIBODY | Anti-PON1 for Mouse/Rat/Human |
Record No:35
| ACCESS NO | 100607 |
| GENE | PIR |
| DESCRIPTION | Pirin |
| NCBI ENTREZ ACCESS NO | 8544 |
| UNIPROT ACCESS NO | O00625 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Pirh2 for Rat/Human |
Record No:36
| ACCESS NO | 100650 |
| GENE | PROS1 |
| DESCRIPTION | Protein S precursor |
| NCBI ENTREZ ACCESS NO | 5627 |
| UNIPROT ACCESS NO | P07225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Plasma proteins |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in coagulation cascade. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21471098 |
| DRUG TARGET | BE0000943 |
| MONCLONAL ANTIBODY | Anti-Protein S for Human |
Record No:37
| ACCESS NO | 100663 |
| GENE | Pdia6 |
| DESCRIPTION | Protein disulfide isomerase family A member 6 |
| NCBI ENTREZ ACCESS NO | 71853 |
| UNIPROT ACCESS NO | Q922R8 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof and Western Blotting |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Considered as chaperone proteins which is often involved in cellular stress which occurs during allergic inflammation and upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PDIA6 for Rat/Human/Mouse |
Record No:38
| ACCESS NO | 100670 |
| GENE | P4hb |
| DESCRIPTION | Prolyl 4-hydroxylase |
| NCBI ENTREZ ACCESS NO | 18453 |
| UNIPROT ACCESS NO | P09103 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in chronic asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | BE0002467 |
| MONCLONAL ANTIBODY | Anti-P4HB for Mouse/Rat/Human |
Record No:39
| ACCESS NO | 100675 |
| GENE | Ppwd1 |
| DESCRIPTION | Peptidylprolyl isomerase A |
| NCBI ENTREZ ACCESS NO | 238831 |
| UNIPROT ACCESS NO | Q8CEC6 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in chronic asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PPWD1 for Mouse/Rat/Human |
Record No:40
| ACCESS NO | 100679 |
| GENE | Ppp1r7 |
| DESCRIPTION | Protein phosphatase 1 regulatory subunit 7 |
| NCBI ENTREZ ACCESS NO | 66385 |
| UNIPROT ACCESS NO | Q3UM45 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergen induced asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PPP1R7 for Dog/Human |
Record No:41
| ACCESS NO | 100684 |
| GENE | Pthlh |
| DESCRIPTION | Parathyroid hormone-related protein |
| NCBI ENTREZ ACCESS NO | 19227 |
| UNIPROT ACCESS NO | P22858 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergen induced asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | BE0001388 |
| MONCLONAL ANTIBODY | Anti-PTHLH for Human |
Record No:42
| ACCESS NO | 100687 |
| GENE | Pdia3 |
| DESCRIPTION | Protein disulfide-isomerase A3 |
| NCBI ENTREZ ACCESS NO | 14827 |
| UNIPROT ACCESS NO | P27773 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergen induced asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Erp57 for Human/Mouse/Rat |
Record No:43
| ACCESS NO | 100695 |
| GENE | Prg2 |
| DESCRIPTION | Proteoglycan 2 |
| NCBI ENTREZ ACCESS NO | 19074 |
| UNIPROT ACCESS NO | Q61878 |
| ORGANISM | TSLP TG mice and BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid Broncho Alveol |
| TECHNIQUES | LC-MS/MS and Western blot and qRT PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Eosinophil activating gene and highly upregulated in BAL cells of mouse but downregulated after Dexamethasone treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22837640 |
| DRUG TARGET | BE0002114 |
| MONCLONAL ANTIBODY | Anti-PRG2 for Human |
Record No:44
| ACCESS NO | 100703 |
| GENE | Pigr |
| DESCRIPTION | Polymeric immunoglobulin receptor |
| NCBI ENTREZ ACCESS NO | 18703 |
| UNIPROT ACCESS NO | O70570 |
| ORGANISM | TSLP TG mice and BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid Broncho Alveol |
| TECHNIQUES | LC-MS/MS and Western blot and qRT PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Delivers IgA on the mucosal surface. Reduced after Dexamethasone treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22837640 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PIGR for Mouse/Human |
Record No:45
| ACCESS NO | 100746 |
| GENE | PAI-1 |
| DESCRIPTION | Plasminogen Activator Inhibitor-1 |
| NCBI ENTREZ ACCESS NO | 5054 |
| UNIPROT ACCESS NO | P05121 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Human mast cell line |
| TECHNIQUES | DNA microarray/RT PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Plays an essential role in tissue remodelling and activated mast cells release huge amount of PAI-1. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 10975829 |
| DRUG TARGET | BE0000240 |
| MONCLONAL ANTIBODY | Anti-PAI1 for Human |
Record No:46
| ACCESS NO | 100760 |
| GENE | Prepl |
| DESCRIPTION | Prolyl endopeptidase-like |
| NCBI ENTREZ ACCESS NO | 213760 |
| UNIPROT ACCESS NO | Q8C167 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after allergen challenge. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:47
| ACCESS NO | 100761 |
| GENE | Prkch |
| DESCRIPTION | Protein kinase C |
| NCBI ENTREZ ACCESS NO | 18755 |
| UNIPROT ACCESS NO | P23298 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in cell mediated immune response. Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:48
| ACCESS NO | 100762 |
| GENE | Ptpn12 |
| DESCRIPTION | Protein-tyrosine phosphatase G1 |
| NCBI ENTREZ ACCESS NO | 19248 |
| UNIPROT ACCESS NO | P35831 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in immune cell trafficking and cellmovement.Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:49
| ACCESS NO | 100781 |
| GENE | PAFAH |
| DESCRIPTION | Platelet-activating factor acetylhydrolase 1b |
| NCBI ENTREZ ACCESS NO | 5048 |
| UNIPROT ACCESS NO | P43034 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | DNA |
| TECHNIQUES | Illumina Human Hap 550Kv3 BeadChip SNP array |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | rs974670 SNP is associated with asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19264973 |
| DRUG TARGET | BE0004103 |
| MONCLONAL ANTIBODY | Anti-PAFAH1B2 fot Mouse/Rat/Human |
Record No:50
| ACCESS NO | 100785 |
| GENE | PHF11 |
| DESCRIPTION | PHD finger protein 11 |
| NCBI ENTREZ ACCESS NO | 51131 |
| UNIPROT ACCESS NO | Q9UIL8 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | DNA |
| TECHNIQUES | Illumina Human Hap 550Kv3 BeadChip SNP array |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Positive regulator of Th1-type cytokine gene expression. Rs2981 SNP is associated with asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19264973 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PHF11 for Human |
Record No:51
| ACCESS NO | 100786 |
| GENE | PTGDR |
| DESCRIPTION | Prostaglandin D2 receptor |
| NCBI ENTREZ ACCESS NO | 5729 |
| UNIPROT ACCESS NO | Q13258 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | DNA |
| TECHNIQUES | Illumina Human Hap 550Kv3 BeadChip SNP array |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Receptor of prostaglandin D2. rs1953367 SNP is associated with asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19264973 |
| DRUG TARGET | BE0000296 |
| MONCLONAL ANTIBODY | N/A |
Record No:52
| ACCESS NO | 100813 |
| GENE | Psat1 |
| DESCRIPTION | Phosphoserine aminotransferase |
| NCBI ENTREZ ACCESS NO | 107272 |
| UNIPROT ACCESS NO | Q99K85 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in short time allergen exposure and downregulated in long exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0000603 |
| MONCLONAL ANTIBODY | N/A |
Record No:53
| ACCESS NO | 100835 |
| GENE | Pon1 |
| DESCRIPTION | Serum paraoxonase |
| NCBI ENTREZ ACCESS NO | 18979 |
| UNIPROT ACCESS NO | P52430 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Downregulated in both short and long term allergen exposure. Probably plays a protective role against oxidative stress induced by reactive. oxygen species |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0000930 |
| MONCLONAL ANTIBODY | Anti-PON1 for Mouse/Rat/Human |
Record No:54
| ACCESS NO | 100838 |
| GENE | Ptprc |
| DESCRIPTION | Protein tyrosine phosphatase |
| NCBI ENTREZ ACCESS NO | 19264 |
| UNIPROT ACCESS NO | Q8C6Q7 |
| ORGANISM | SWR/J mouse |
| DISEASE PHENOTYPE | Allergic conjunctivitis |
| SAMPLE | Conjunctival Tissues |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Required for T cell activation. Upregulated in conjuctiva. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18658092 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD45R for Mouse/Human |
Record No:55
| ACCESS NO | 100839 |
| GENE | Ptpn13 |
| DESCRIPTION | Non receptor type 13 |
| NCBI ENTREZ ACCESS NO | 19249 |
| UNIPROT ACCESS NO | Q64512 |
| ORGANISM | SWR/J mouse |
| DISEASE PHENOTYPE | Allergic conjunctivitis |
| SAMPLE | Conjunctival Tissues |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in conjunctival tissues of allergen induced mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18658092 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PTPN13 for Human |
Record No:56
| ACCESS NO | 100925 |
| GENE | Pex13 |
| DESCRIPTION | Peroxisomal biogenesis factor 13 |
| NCBI ENTREZ ACCESS NO | 72129 |
| UNIPROT ACCESS NO | Q9D0K1 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Downregulated in ovalbumin sensitized patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:57
| ACCESS NO | 100927 |
| GENE | Prrg4 |
| DESCRIPTION | Proline rich Gla (G-carboxyglutamic acid) 4 |
| NCBI ENTREZ ACCESS NO | 228413 |
| UNIPROT ACCESS NO | Q8BGN6 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after induction with food allergens. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:58
| ACCESS NO | 100962 |
| GENE | PTX3 |
| DESCRIPTION | Pentraxin 3 |
| NCBI ENTREZ ACCESS NO | 5806 |
| UNIPROT ACCESS NO | P26022 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Human airway smooth muscle cells |
| TECHNIQUES | RT PCR and ELISA |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Activates and regulates complements and bind to pathogens. Overexpressed in airway smooth muscle cells of asthmatic patientsasthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22529962 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Pentraxin 3 for Mouse/Human |
Record No:59
| ACCESS NO | 101019 |
| GENE | PELI1 |
| DESCRIPTION | Pellino E3 ubiquitin protein ligase 1 |
| NCBI ENTREZ ACCESS NO | 57162 |
| UNIPROT ACCESS NO | Q96FA3 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows highest expression in patients with neutrophilic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | BE0000925 |
| MONCLONAL ANTIBODY | N/A |
Record No:60
| ACCESS NO | 101020 |
| GENE | PI3 |
| DESCRIPTION | Peptidase inhibitor 3 |
| NCBI ENTREZ ACCESS NO | 5266 |
| UNIPROT ACCESS NO | P19957 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is a biomarkers of neutrophilic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | BE0002379 |
| MONCLONAL ANTIBODY | Anti-Elafin/Skalp for Human |
Record No:61
| ACCESS NO | 101027 |
| GENE | PRDX2 |
| DESCRIPTION | Peroxiredoxin-2 |
| NCBI ENTREZ ACCESS NO | 7001 |
| UNIPROT ACCESS NO | P32119 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly upregulated in atopic eczema. It is involved in inflammatory responses. Presence of this protein in vernix of the atopic eczema group indicate that the skin of these neonates might be prone to develop inflammation and may possibly have a physiological association with AE. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | BE0001972 |
| MONCLONAL ANTIBODY | Anti-Peroxiredoxin 2 [EPR5154] for Mouse/Rat/Human |
Record No:62
| ACCESS NO | 101039 |
| GENE | PLEC |
| DESCRIPTION | Plectin |
| NCBI ENTREZ ACCESS NO | 5339 |
| UNIPROT ACCESS NO | Q15149 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly upregulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Plectin for Mouse/Rat/Human |
Record No:63
| ACCESS NO | 101040 |
| GENE | PSAPL1 |
| DESCRIPTION | Proactivator polypeptide-like 1 |
| NCBI ENTREZ ACCESS NO | 768239 |
| UNIPROT ACCESS NO | Q6NUJ1 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly upregulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:64
| ACCESS NO | 101050 |
| GENE | PSMA3 |
| DESCRIPTION | Proteasome subunit alpha type-3 |
| NCBI ENTREZ ACCESS NO | 5684 |
| UNIPROT ACCESS NO | P25788 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly down regulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | BE0003912 |
| MONCLONAL ANTIBODY | Anti-Proteasome 20S alpha 3 for Mouse/Rat/Human |
Record No:65
| ACCESS NO | 101052 |
| GENE | PSMB5 |
| DESCRIPTION | Proteasome subunit beta type-5 |
| NCBI ENTREZ ACCESS NO | 5693 |
| UNIPROT ACCESS NO | P28074 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly down regulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | BE0002348 |
| MONCLONAL ANTIBODY | N/A |
Record No:66
| ACCESS NO | 101076 |
| GENE | POSTN |
| DESCRIPTION | Periostin |
| NCBI ENTREZ ACCESS NO | 10631 |
| UNIPROT ACCESS NO | Q15063 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is a candidate for the predictive marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23943655 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Periostin for Human |
Record No:67
| ACCESS NO | 101080 |
| GENE | POSTN |
| DESCRIPTION | Periostin |
| NCBI ENTREZ ACCESS NO | 10631 |
| UNIPROT ACCESS NO | Q15063 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Airway epithelial brushings |
| TECHNIQUES | qPCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Being a component of three-gene-mean provides a measurement of Th2 airway inflammation that is clinically relevant and that can serve as a valuable tool to evaluate non-invasive biomarkers to predict treatment responses to existing and emerging asthma |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23866775 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Periostin for Human |
Record No:68
| ACCESS NO | 101083 |
| GENE | POSTN |
| DESCRIPTION | Periostin |
| NCBI ENTREZ ACCESS NO | 10631 |
| UNIPROT ACCESS NO | Q15063 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Serum periostin appears to be a useful biomarker for the development of airflow limitation in asthmatic patients on inhaled corticosteroids. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23791506 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Periostin for Human |
Record No:69
| ACCESS NO | 101100 |
| GENE | PSMD3 |
| DESCRIPTION | Proteasome 26S subunit |
| NCBI ENTREZ ACCESS NO | 5709 |
| UNIPROT ACCESS NO | O43242 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | gDNA |
| TECHNIQUES | SNP typing |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | SNP related alleles of this gene in combination with deregulated phosphatidylcholines in asthmatics may serve as biomarker of this disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23452035 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:70
| ACCESS NO | 101137 |
| GENE | POSTN |
| DESCRIPTION | Periostin |
| NCBI ENTREZ ACCESS NO | 10631 |
| UNIPROT ACCESS NO | Q15063 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Periostin is a systemic biomarker of airway eosinophilia in asthmatic patients and has potential utility in patient selection for emerging asthma therapeutics targeting TH2 inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22857879 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Periostin for Human |
Record No:71
| ACCESS NO | 101155 |
| GENE | PDGF-bb |
| DESCRIPTION | Platelet-derived growth factor beta polypeptide homodimer |
| NCBI ENTREZ ACCESS NO | 5155 |
| UNIPROT ACCESS NO | P01127 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This gene is involved in neovascularization/remodulation after tissue damage. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:72
| ACCESS NO | 101163 |
| GENE | PTN (OSF-1) |
| DESCRIPTION | Pleotrophin |
| NCBI ENTREZ ACCESS NO | 5764 |
| UNIPROT ACCESS NO | P21246 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
| SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
| TECHNIQUES | 2D-DIGE and qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is overexpressed in various types of tolerogenic dendritic cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22464673 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:73
| ACCESS NO | 101196 |
| GENE | PFKFB4 |
| DESCRIPTION | 6-phosphofructo-2-kinase |
| NCBI ENTREZ ACCESS NO | 5210 |
| UNIPROT ACCESS NO | Q16877 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | BE0003931 |
| MONCLONAL ANTIBODY | Anti-PFKFB4 for Human |
Record No:74
| ACCESS NO | 101217 |
| GENE | PTCD2 |
| DESCRIPTION | Pentatricopeptide repeat-containing protein 2 |
| NCBI ENTREZ ACCESS NO | 79810 |
| UNIPROT ACCESS NO | Q8WV60 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:75
| ACCESS NO | 101316 |
| GENE | PSF1 |
| DESCRIPTION | Transporter 1 ATP-binding cassette sub-family B(TAP1) |
| NCBI ENTREZ ACCESS NO | 6890 |
| UNIPROT ACCESS NO | Q03518 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy(Comparison of Dendritic cell proteome in atopic and non atopic patients) |
| SAMPLE | Dendritic cell |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in initiation of replication. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19494521 |
| DRUG TARGET | BE0003109 |
| MONCLONAL ANTIBODY | Anti-PSF1 for Mouse/Rat/Human |
Record No:76
| ACCESS NO | 101320 |
| GENE | PSMC5 |
| DESCRIPTION | 26S proteasome |
| NCBI ENTREZ ACCESS NO | 5705 |
| UNIPROT ACCESS NO | P62195 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy(Comparison of Dendritic cell proteome in atopic and non atopic patients) |
| SAMPLE | Dendritic cell |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in antigen processing and regulates NF kappa beta activation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19494521 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:77
| ACCESS NO | 101324 |
| GENE | PHB |
| DESCRIPTION | Prohibitin |
| NCBI ENTREZ ACCESS NO | 5245 |
| UNIPROT ACCESS NO | P35232 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy(Comparison of Dendritic cell proteome in atopic and non atopic patients) |
| SAMPLE | Dendritic cell |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Plays a key role in inflammation and differentially expressed after Der P1 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19494521 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Prohibitin for Mouse/Rat/Human/Pig |
Record No:78
| ACCESS NO | 101325 |
| GENE | PSME2 |
| DESCRIPTION | Proteasome activator subunit 2 (PSME2) |
| NCBI ENTREZ ACCESS NO | 5721 |
| UNIPROT ACCESS NO | Q9UL46 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy(Comparison of Dendritic cell proteome in atopic and non atopic patients) |
| SAMPLE | Dendritic cell |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in antigen processing. Differentially expressed after Der P1 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19494521 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PSME2 for Mouse/Rat/Human |
Record No:79
| ACCESS NO | 101329 |
| GENE | PRDX4 |
| DESCRIPTION | Thioredoxin peroxidise PRXD4 |
| NCBI ENTREZ ACCESS NO | 10549 |
| UNIPROT ACCESS NO | Q13162 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy(Comparison of Dendritic cell proteome in atopic and non atopic patients) |
| SAMPLE | Dendritic cell |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Differentially expressed in atopic individuals after administering active and inactive DerP1. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19494521 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Peroxiredoxin 4 for Mouse/Rat/Human |
Record No:80
| ACCESS NO | 101365 |
| GENE | Ppp2r1a |
| DESCRIPTION | Protein phosphatase 2 regulatory subunit A isoform A |
| NCBI ENTREZ ACCESS NO | 51792 |
| UNIPROT ACCESS NO | Q76MZ3 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in cellular metabolism and differentially expressed in chronic asthma mouse model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | BE0003750 |
| MONCLONAL ANTIBODY | Anti-PPP2R1A for Mouse/Rat/Human |
Record No:81
| ACCESS NO | 101367 |
| GENE | Pcx |
| DESCRIPTION | Pyruvate carboxylase |
| NCBI ENTREZ ACCESS NO | 18563 |
| UNIPROT ACCESS NO | E9QPD7 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in cellular metabolism and downregulated in chronic asthma mouse model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PCB for Mouse/Rat/Human/Cow |
Record No:82
| ACCESS NO | 101369 |
| GENE | Phpt1 |
| DESCRIPTION | Phosphohistidine phosphatase |
| NCBI ENTREZ ACCESS NO | 75454 |
| UNIPROT ACCESS NO | Q9DAK9 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in cellular metabolism and expressed in chronic asthma mouse model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:83
| ACCESS NO | 101374 |
| GENE | Psmd11 |
| DESCRIPTION | Proteasome 26S non-ATPase regulatory subunit 11 |
| NCBI ENTREZ ACCESS NO | 69077 |
| UNIPROT ACCESS NO | Q8BG32 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in chronic asthma mouse model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PSMD11 for Mouse/Human |
Record No:84
| ACCESS NO | 101375 |
| GENE | Psmb9 |
| DESCRIPTION | Proteasome subunit type 9 precursor (LMP-2) |
| NCBI ENTREZ ACCESS NO | 16912 |
| UNIPROT ACCESS NO | P28076 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in chronic asthma mouse model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:85
| ACCESS NO | 101433 |
| GENE | P2ry2 |
| DESCRIPTION | Purinergic receptor P2Y G-protein coupled 2 |
| NCBI ENTREZ ACCESS NO | 18442 |
| UNIPROT ACCESS NO | P35383 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0002401 |
| MONCLONAL ANTIBODY | N/A |
Record No:86
| ACCESS NO | 101440 |
| GENE | Plek |
| DESCRIPTION | Pleckstrin |
| NCBI ENTREZ ACCESS NO | 56193 |
| UNIPROT ACCESS NO | Q9JHK5 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3hours and 12 hours of fungal allergen induction in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Pleckstrin for Human |
Record No:87
| ACCESS NO | 101447 |
| GENE | Pim1 |
| DESCRIPTION | Proviral integration site 1 |
| NCBI ENTREZ ACCESS NO | 18712 |
| UNIPROT ACCESS NO | Q8CFN8 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3hours and 12 hours of fungal allergen induction in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0001277 |
| MONCLONAL ANTIBODY | Anti-PIM1 for Mouse/Human |
Record No:88
| ACCESS NO | 101457 |
| GENE | Ptgfr |
| DESCRIPTION | Prostaglandin F receptor |
| NCBI ENTREZ ACCESS NO | 19220 |
| UNIPROT ACCESS NO | P43117 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0000610 |
| MONCLONAL ANTIBODY | Anti-Prostaglandin F2 alpha Receptor for Human |
Record No:89
| ACCESS NO | 101464 |
| GENE | Ptges |
| DESCRIPTION | Prostaglandin E synthase |
| NCBI ENTREZ ACCESS NO | 64292 |
| UNIPROT ACCESS NO | Q9JM51 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PTGES2 for Human |
Record No:90
| ACCESS NO | 101471 |
| GENE | Ptgir |
| DESCRIPTION | Prostaglandin I receptor (IP) |
| NCBI ENTREZ ACCESS NO | 19222 |
| UNIPROT ACCESS NO | P43252 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0000475 |
| MONCLONAL ANTIBODY | Anti-Prostaglandin I2 for Human |
Record No:91
| ACCESS NO | 101479 |
| GENE | Ptges |
| DESCRIPTION | Prostaglandin E synthase |
| NCBI ENTREZ ACCESS NO | 64292 |
| UNIPROT ACCESS NO | Q9JM51 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of fungal allergen challenge in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:92
| ACCESS NO | 101492 |
| GENE | Pglyrp1 |
| DESCRIPTION | Peptidoglycan recognition protein 1 |
| NCBI ENTREZ ACCESS NO | 21946 |
| UNIPROT ACCESS NO | O88593 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PGRPS for Mouse/Human |
Record No:93
| ACCESS NO | 101523 |
| GENE | Ptpn2 |
| DESCRIPTION | Protein tyrosine phosphatase non-receptor type 2 |
| NCBI ENTREZ ACCESS NO | 19255 |
| UNIPROT ACCESS NO | Q06180 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:94
| ACCESS NO | 101526 |
| GENE | Ptgfr |
| DESCRIPTION | Prostaglandin F receptor |
| NCBI ENTREZ ACCESS NO | 19220 |
| UNIPROT ACCESS NO | P43117 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0000610 |
| MONCLONAL ANTIBODY | Anti-Prostaglandin F2 alpha Receptor for Human |
Record No:95
| ACCESS NO | 101565 |
| GENE | PIGR |
| DESCRIPTION | Polymeric immunoglobulin receptor |
| NCBI ENTREZ ACCESS NO | 18703 |
| UNIPROT ACCESS NO | O70570 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Induced by both OVA challenge and IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:96
| ACCESS NO | 101581 |
| GENE | Pfc |
| DESCRIPTION | Complement factor properdin |
| NCBI ENTREZ ACCESS NO | 18636 |
| UNIPROT ACCESS NO | P11680 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in innate immunity and expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:97
| ACCESS NO | 101592 |
| GENE | Plat |
| DESCRIPTION | Plasminogen activator tissue |
| NCBI ENTREZ ACCESS NO | 18791 |
| UNIPROT ACCESS NO | P11214 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in coagulation and expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | BE0001088 |
| MONCLONAL ANTIBODY | Anti-TPA Tissue Plasminogen Activator for Mouse/Rat |
Record No:98
| ACCESS NO | 101624 |
| GENE | Pim3 |
| DESCRIPTION | Proviral integration site 3 |
| NCBI ENTREZ ACCESS NO | 223775 |
| UNIPROT ACCESS NO | P58750 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:99
| ACCESS NO | 101630 |
| GENE | Prdx2 |
| DESCRIPTION | Peroxiredoxin-2 |
| NCBI ENTREZ ACCESS NO | 21672 |
| UNIPROT ACCESS NO | Q61171 |
| ORGANISM | Female Balb/c Mice |
| DISEASE PHENOTYPE | Food allergy caused by Ovomucoid |
| SAMPLE | Plasma |
| TECHNIQUES | MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed in Ovomucoid sensitized mouse. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17897766 |
| DRUG TARGET | BE0001972 |
| MONCLONAL ANTIBODY | Anti-Peroxiredoxin 2 for Mouse/Rat/Human |
Record No:100
| ACCESS NO | 101647 |
| GENE | PLAU |
| DESCRIPTION | Urokinase type plasminogen activator |
| NCBI ENTREZ ACCESS NO | 5328 |
| UNIPROT ACCESS NO | P00749 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Insect allergy(Bee venom immunotherapy) |
| SAMPLE | Peripheral Blood Mononuclear cells |
| TECHNIQUES | Gene chip microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Induced by osteopontin. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15867867 |
| DRUG TARGET | BE0000895 |
| MONCLONAL ANTIBODY | Anti-Urokinase for Mouse/Rat/Human |
Record No:101
| ACCESS NO | 101649 |
| GENE | Prdx2 |
| DESCRIPTION | Peroxiredoxin 2 |
| NCBI ENTREZ ACCESS NO | 21672 |
| UNIPROT ACCESS NO | Q61171 |
| ORGANISM | Male BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | 2D electrophoresis and MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16100447 |
| DRUG TARGET | BE0004641 |
| MONCLONAL ANTIBODY | Anti-Peroxiredoxin 2 for Mouse/Rat/Human |
Record No:102
| ACCESS NO | 101655 |
| GENE | Prdx1 |
| DESCRIPTION | Peroxiredoxin 1 |
| NCBI ENTREZ ACCESS NO | 11758 |
| UNIPROT ACCESS NO | P35700 |
| ORGANISM | Male BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | 2D electrophoresis and MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16100447 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Peroxiredoxin 1 for Human |
Record No:103
| ACCESS NO | 101660 |
| GENE | Prdx6 |
| DESCRIPTION | Peroxiredoxin 6 |
| NCBI ENTREZ ACCESS NO | 11758 |
| UNIPROT ACCESS NO | O08709 |
| ORGANISM | Male BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | 2D electrophoresis and MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16100447 |
| DRUG TARGET | BE0004641 |
| MONCLONAL ANTIBODY | Anti-Peroxiredoxin 6 for Mouse/Rat/Human |
Record No:104
| ACCESS NO | 101668 |
| GENE | Parp1 |
| DESCRIPTION | Poly (ADP-ribose) polymerase 1 |
| NCBI ENTREZ ACCESS NO | 25591 |
| UNIPROT ACCESS NO | P27008 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Ferric Reducing Ability Assay and Poly(ADP-ribosyl |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Minocycline-treated/ovalbumin-challenged mice showed reduction in poly(ADP-ribose) immunoreactivity in lung and it correlates with decreased oxidative DNA damage. However the drug can not block direct PARP activation in lungs of N-methyl-N -nitro-N-nitroso-guanidine-treated mice or H2O2-treated cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23184953 |
| DRUG TARGET | BE0001717 |
| MONCLONAL ANTIBODY | N/A |
Record No:105
| ACCESS NO | 101683 |
| GENE | PLA2G10 (hGX-sPLA2) |
| DESCRIPTION | Human Group X (GX) phospholipase A2 |
| NCBI ENTREZ ACCESS NO | 8399 |
| UNIPROT ACCESS NO | O15496 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and blockade of Human Group X Secreted Phospholipase A2 |
| SAMPLE | Plasma |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics (Pha |
| STUDY | Low Throughput |
| COMMENTS | Deficiency in this protein impairs development of the asthma phenotype. A mouse model with knock out in mouse GX-sPLA2 but knock in (transgenic) human GX-sPLA2 restores the allergen-induced airway infiltration by inflammatory cells and hyperresponsiveness. However the use of an inhibitor RO061606 to block this gene significantly decreased allergen-induced airway inflammation as well as mucus hypersecretion and hyperresponsiveness. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21652694 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:106
| ACCESS NO | 101692 |
| GENE | Postn |
| DESCRIPTION | Periostin |
| NCBI ENTREZ ACCESS NO | 50706 |
| UNIPROT ACCESS NO | Q62009 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Airway Epithelial Cells |
| TECHNIQUES | Standard molecular biology and cell biology techni |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It stimulates TGF beta signaling pathway in a mechanism involving matrix metalloproteinases 2 and 9. Over expression of periostin causes TGF beta dependent secretion of type 1 collagen by airway fibroblasts. Periostin alters collagen fibrillogenesis or cross-linking and leads to stiffening of the matrix. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20660732 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Periostin [EPR6989(N)(B)] for human |
Record No:107
| ACCESS NO | 101708 |
| GENE | PRG2 |
| DESCRIPTION | Eosinophil granule major basic protein (MBP) |
| NCBI ENTREZ ACCESS NO | 5553 |
| UNIPROT ACCESS NO | P13727 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This eosinophilic granule protein is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PRG2 [1.B.787] for Human |
Record No:108
| ACCESS NO | 101724 |
| GENE | PSME1 |
| DESCRIPTION | Proteasome activator complex subunit 1 |
| NCBI ENTREZ ACCESS NO | 5720 |
| UNIPROT ACCESS NO | Q06323 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protease is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PSME1 [EPR10967(B)] for Mouse/Rat/Human |
Record No:109
| ACCESS NO | 101729 |
| GENE | PSME2 |
| DESCRIPTION | Proteasome activator complex subunit 2 |
| NCBI ENTREZ ACCESS NO | 5721 |
| UNIPROT ACCESS NO | Q9UL46 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protease is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PSME2 [EPR14931] for Mouse/Rat/Human |
Record No:110
| ACCESS NO | 101734 |
| GENE | PKM |
| DESCRIPTION | Pyruvate kinase M1 isozyme |
| NCBI ENTREZ ACCESS NO | 5315 |
| UNIPROT ACCESS NO | P14618 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000088 |
| MONCLONAL ANTIBODY | Anti-PKM2 [EPR10138(B)] for Mouse/Rat/Human |
Record No:111
| ACCESS NO | 101736 |
| GENE | PON1 |
| DESCRIPTION | Paraoxonase 1 |
| NCBI ENTREZ ACCESS NO | 5444 |
| UNIPROT ACCESS NO | F8WF42 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PON1 [17A12] for Mouse/Rat/Human |
Record No:112
| ACCESS NO | 101747 |
| GENE | PDXK |
| DESCRIPTION | Pyridoxal kinase (pyridoxine kinase) |
| NCBI ENTREZ ACCESS NO | 8566 |
| UNIPROT ACCESS NO | C9JMR7 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000042 |
| MONCLONAL ANTIBODY | Anti-PDXK.1 [5H5] for Human |
Record No:113
| ACCESS NO | 101749 |
| GENE | PYGL |
| DESCRIPTION | Glycogen phosphorylase |
| NCBI ENTREZ ACCESS NO | 5836 |
| UNIPROT ACCESS NO | E9PK47 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000007 |
| MONCLONAL ANTIBODY | N/A |
Record No:114
| ACCESS NO | 101752 |
| GENE | PCBD1 |
| DESCRIPTION | 4a-Hydroxytetrahydrobiopterin dehydratase |
| NCBI ENTREZ ACCESS NO | 5092 |
| UNIPROT ACCESS NO | Q6LEE1 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0004555 |
| MONCLONAL ANTIBODY | Anti-PCBD1 [EPR9760(B)] for Mouse/Rat/Human |
Record No:115
| ACCESS NO | 101753 |
| GENE | PTGDS |
| DESCRIPTION | Prostaglandin-H2 D-isomerase |
| NCBI ENTREZ ACCESS NO | 5730 |
| UNIPROT ACCESS NO | F8W7I2 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Prostaglandin D Synthase (Lipocalin) [EP12357] for Mouse/Rat/Human |
Record No:116
| ACCESS NO | 101761 |
| GENE | PGLYRP1 |
| DESCRIPTION | Peptidoglycan recognition protein (PGRP-S) |
| NCBI ENTREZ ACCESS NO | 8993 |
| UNIPROT ACCESS NO | O75594 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This local matrix protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PGRPS [188C424] for Mouse/Human |
Record No:117
| ACCESS NO | 101789 |
| GENE | PLG |
| DESCRIPTION | Plasminogen [contains angiostatin] |
| NCBI ENTREZ ACCESS NO | 5340 |
| UNIPROT ACCESS NO | Q5TEH5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This serum protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000211 |
| MONCLONAL ANTIBODY | N/A |
Record No:118
| ACCESS NO | 101830 |
| GENE | PTPRS |
| DESCRIPTION | Protein tyrosine phosphatase receptor type |
| NCBI ENTREZ ACCESS NO | 5802 |
| UNIPROT ACCESS NO | Q13332 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is down regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0003657 |
| MONCLONAL ANTIBODY | N/A |
Record No:119
| ACCESS NO | 101831 |
| GENE | PLXND1 |
| DESCRIPTION | Plexin D1 |
| NCBI ENTREZ ACCESS NO | 23129 |
| UNIPROT ACCESS NO | Q9Y4D7 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is down regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:120
| ACCESS NO | 101838 |
| GENE | PIR |
| DESCRIPTION | Pirin |
| NCBI ENTREZ ACCESS NO | 8544 |
| UNIPROT ACCESS NO | O00625 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is down regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:121
| ACCESS NO | 101850 |
| GENE | PILRA |
| DESCRIPTION | Paired immunoglobulin-like receptor- alpha |
| NCBI ENTREZ ACCESS NO | 29992 |
| UNIPROT ACCESS NO | Q9UKJ1 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic Rhinitis induced by pollen allergen |
| SAMPLE | Nasal lavage fluids |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This anti inflammatory gene showed higher expression levels in patients than in controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15836756 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:122
| ACCESS NO | 101875 |
| GENE | PDIA3 |
| DESCRIPTION | Protein disulfide-isomerase |
| NCBI ENTREZ ACCESS NO | 2923 |
| UNIPROT ACCESS NO | S55507 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Fibroblast |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic fibroblasts comparative to normal fibroblasts. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15468290 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-ERp57 for Mouse/Rat/Human |
Record No:123
| ACCESS NO | 101882 |
| GENE | P4HA2 |
| DESCRIPTION | Prolyl 4-hydroxylase alpha-2 subunit |
| NCBI ENTREZ ACCESS NO | 8974 |
| UNIPROT ACCESS NO | O15460 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Fibroblast |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic fibroblasts comparative to normal fibroblasts. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15468290 |
| DRUG TARGET | BE0002253 |
| MONCLONAL ANTIBODY | N/A |
Record No:124
| ACCESS NO | 101887 |
| GENE | PGM3 |
| DESCRIPTION | Phosphoacetyl-glucosamine mutase |
| NCBI ENTREZ ACCESS NO | 5238 |
| UNIPROT ACCESS NO | O95394 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Fibroblast |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF and Semi qPCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This protein is upregulated in atopic fibroblasts comparative to normal fibroblasts. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15468290 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PGM3 for Mouse/Human |
Record No:125
| ACCESS NO | 101888 |
| GENE | PHGDH |
| DESCRIPTION | 3-Phosphoglycerate dehydrogenase |
| NCBI ENTREZ ACCESS NO | 26227 |
| UNIPROT ACCESS NO | O43175 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Fibroblast |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is down regulated in atopic fibroblasts comparative to normal fibroblasts. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15468290 |
| DRUG TARGET | BE0000161 |
| MONCLONAL ANTIBODY | Anti-PHGDH for Human |
Record No:126
| ACCESS NO | 101901 |
| GENE | PROM1 |
| DESCRIPTION | Prominin-like protein 1 precursor |
| NCBI ENTREZ ACCESS NO | 8842 |
| UNIPROT ACCESS NO | O43490 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:127
| ACCESS NO | 101949 |
| GENE | PRAM1 |
| DESCRIPTION | PML-RARA-regulated adaptor molecule 1 |
| NCBI ENTREZ ACCESS NO | 84106 |
| UNIPROT ACCESS NO | Q96QH2 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:128
| ACCESS NO | 101953 |
| GENE | PTPRE |
| DESCRIPTION | Protein tyrosine phosphatase receptor type E |
| NCBI ENTREZ ACCESS NO | 5791 |
| UNIPROT ACCESS NO | P23469 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Up regulated in asthma. Involved in cellular assembly and organisation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | BE0003568 |
| MONCLONAL ANTIBODY | Anti-PTP epsilon for Mouse/Rat/Human |
Record No:129
| ACCESS NO | 101959 |
| GENE | PHLDA1 |
| DESCRIPTION | Pleckstrin homology-like domain family A member 1 |
| NCBI ENTREZ ACCESS NO | 22822 |
| UNIPROT ACCESS NO | Q8WV24 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PHLDA1 for Human |
Record No:130
| ACCESS NO | 101989 |
| GENE | PPAT |
| DESCRIPTION | Phosphoribosyl pyrophosphate amidotransferase |
| NCBI ENTREZ ACCESS NO | 5471 |
| UNIPROT ACCESS NO | Q06203 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in patients with allergic rhinitis with or without asthma in the upper airways. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | BE0000374 |
| MONCLONAL ANTIBODY | Anti-Phosphoribosyl pyrophosphate amidotransferase antibody for Mouse/Rat/Human |
Record No:131
| ACCESS NO | 102011 |
| GENE | PCK2 |
| DESCRIPTION | Phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| NCBI ENTREZ ACCESS NO | 5106 |
| UNIPROT ACCESS NO | Q16822 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in the lower airways in patients with allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PCK2 for Mouse/Rat/Human |
Record No:132
| ACCESS NO | 102022 |
| GENE | PDE4D |
| DESCRIPTION | Phosphodiesterase 4D cAMP-specific |
| NCBI ENTREZ ACCESS NO | 5144 |
| UNIPROT ACCESS NO | Q08499 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Primary nasal and bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Downregulated in upper airways in allergic rhinitis patients with or without asthma.(Data in supplimentary table.) |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | BE0001287 |
| MONCLONAL ANTIBODY | Anti-PDE4D for Mouse/Rat/Human |
Record No:133
| ACCESS NO | 102038 |
| GENE | PCDH7 |
| DESCRIPTION | Protocadherin 7 |
| NCBI ENTREZ ACCESS NO | 5099 |
| UNIPROT ACCESS NO | O60245 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PCDH7 for Mouse/Rat/Human |
Record No:134
| ACCESS NO | 102039 |
| GENE | PLCB1 |
| DESCRIPTION | Phospholipase C beta 1 |
| NCBI ENTREZ ACCESS NO | 23236 |
| UNIPROT ACCESS NO | Q9NQ66 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Phospholipase C beta 1 for Mouse/Rat/Human |
Record No:135
| ACCESS NO | 102040 |
| GENE | PSD3 |
| DESCRIPTION | Pleckstrin and Sec7 domain containing 3 |
| NCBI ENTREZ ACCESS NO | 23362 |
| UNIPROT ACCESS NO | Q9NYI0 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:136
| ACCESS NO | 102058 |
| GENE | PLA2G4A |
| DESCRIPTION | Phospholipase A2 group IVA |
| NCBI ENTREZ ACCESS NO | 5321 |
| UNIPROT ACCESS NO | P47712 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Nasal epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | BE0000657 |
| MONCLONAL ANTIBODY | Anti-Phospholipase A2 for Human |
Record No:137
| ACCESS NO | 102059 |
| GENE | PNMAL1 |
| DESCRIPTION | PNMA-like 1 |
| NCBI ENTREZ ACCESS NO | 55228 |
| UNIPROT ACCESS NO | Q86V59 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Nasal epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:138
| ACCESS NO | 102081 |
| GENE | PTGER2 |
| DESCRIPTION | Prostaglandin E receptor 2 |
| NCBI ENTREZ ACCESS NO | 5732 |
| UNIPROT ACCESS NO | P43116 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthma. Involved in Involved in leukotriene and prostaglandin signalling. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | BE0000368 |
| MONCLONAL ANTIBODY | Anti-Prostaglandin E Receptor EP2 for Rat/Cow/Human |
Record No:139
| ACCESS NO | 102082 |
| GENE | PITRM1 |
| DESCRIPTION | Pitrilysin metallopeptidase 1 |
| NCBI ENTREZ ACCESS NO | 10531 |
| UNIPROT ACCESS NO | Q5JRX3 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in protease activity and regulation and degrades mitochondrial peptides. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PITRM1 for Human |
Record No:140
| ACCESS NO | 102094 |
| GENE | PGM1 |
| DESCRIPTION | Phosphoglucomutase 1 |
| NCBI ENTREZ ACCESS NO | 5236 |
| UNIPROT ACCESS NO | P36871 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentially expressed in asthma. Plays a role in glucose breakdown and may have a role in calcium signalling. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | BE0004461 |
| MONCLONAL ANTIBODY | Anti-PGM1 for Human |
Record No:141
| ACCESS NO | 102125 |
| GENE | PCGF5 |
| DESCRIPTION | Polycomb group ring finger 5 |
| NCBI ENTREZ ACCESS NO | 84333 |
| UNIPROT ACCESS NO | Q86SE9 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Differentialy expressed in asthma. Transcriptional repressor. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-PCGF5 Mouse/Rat/Human |
Record No:142
| ACCESS NO | 102135 |
| GENE | PLXDC1 |
| DESCRIPTION | Plexin domain containing 1 |
| NCBI ENTREZ ACCESS NO | 57125 |
| UNIPROT ACCESS NO | Q8IUK5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TEM7 for Human |
Record No:143
| ACCESS NO | 102152 |
| GENE | POSTN |
| DESCRIPTION | Periostin |
| NCBI ENTREZ ACCESS NO | 10631 |
| UNIPROT ACCESS NO | Q15063 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Bronchial Biopsy |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | GSE41649 |
| REFERENCE | 19842841 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Periostin for Human |