BROWSE RESULT OF R
| 69 Records |
| ACCESS NO | 100023 |
| GENE | RRM2 |
| DESCRIPTION | Ribonucleotide reductase M2 |
| NCBI ENTREZ ACCESS NO | 6241 |
| UNIPROT ACCESS NO | P31350 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in low SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | BE0002450 |
| MONCLONAL ANTIBODY | Anti-RRM2 for Human |
Record No:2
| ACCESS NO | 100049 |
| GENE | RPS4Y1 |
| DESCRIPTION | Ribosomal protein S4 Y-linked 1 |
| NCBI ENTREZ ACCESS NO | 6192 |
| UNIPROT ACCESS NO | P22090 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in high SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:3
| ACCESS NO | 100099 |
| GENE | Retnlb |
| DESCRIPTION | Resistin-like b |
| NCBI ENTREZ ACCESS NO | 57263 |
| UNIPROT ACCESS NO | Q99P86 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This goblet cell specific gene is selectively induced by IL-13. This gene is not induced upon allergen challenge or IL-4 challenge in IL-13 deficient mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:4
| ACCESS NO | 100167 |
| GENE | RASD1 |
| DESCRIPTION | RAS - dexamethasone induced 1 |
| NCBI ENTREZ ACCESS NO | 51655 |
| UNIPROT ACCESS NO | Q9Y272 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:5
| ACCESS NO | 100204 |
| GENE | RAB3B |
| DESCRIPTION | RAS related protein 3B |
| NCBI ENTREZ ACCESS NO | 5865 |
| UNIPROT ACCESS NO | P20337 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene codes for a metabolic enzyme significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RAB3B [EPR12987] for Mouse/Rat/Human |
Record No:6
| ACCESS NO | 100242 |
| GENE | RCSD1 |
| DESCRIPTION | RCSD domain containing 1 |
| NCBI ENTREZ ACCESS NO | 92241 |
| UNIPROT ACCESS NO | Q6JBY9 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is significantly down regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RCSD 1 for Human |
Record No:7
| ACCESS NO | 100278 |
| GENE | RBP7 |
| DESCRIPTION | Retinol binding protein 7 |
| NCBI ENTREZ ACCESS NO | 116362 |
| UNIPROT ACCESS NO | Q96R05 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays and real time |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It belongs to the fatty acid binding protein family. PPARalpha and PPARgamma can regulate the hepatic RBP7 level in response to synthetic PPAR ligands. These have been shown to exert potent anti-inflammatory effects that are primarily mediated through the modulation of pro-inflammatory gene expression and inflammatory cell functions. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | BE0000532 |
| MONCLONAL ANTIBODY | N/A |
Record No:8
| ACCESS NO | 100310 |
| GENE | Rras |
| DESCRIPTION | Harvey rat sarcoma oncogene subgroup - r |
| NCBI ENTREZ ACCESS NO | 361568 |
| UNIPROT ACCESS NO | D3Z8L7 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in regulation of actin cytoskeleton and IgE receptor signalling pathway. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RRAS2 for Human |
Record No:9
| ACCESS NO | 100312 |
| GENE | Rac2 |
| DESCRIPTION | Ras-related c3 botulinum substrate 2 |
| NCBI ENTREZ ACCESS NO | 366957 |
| UNIPROT ACCESS NO | Q5U1Y2 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is a major component of several signal transduction pathways such as MAPK signalling pathway and IgE receptor signalling pathway. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | BE0001142 |
| MONCLONAL ANTIBODY | Anti-RAC2 [AT2G11] for Human |
Record No:10
| ACCESS NO | 100329 |
| GENE | Rab7a |
| DESCRIPTION | RAB7 member RAS oncogene family |
| NCBI ENTREZ ACCESS NO | 29448 |
| UNIPROT ACCESS NO | P09527 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) and qRT- |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is downregulated in asthmatic lung. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | BE0004485 |
| MONCLONAL ANTIBODY | Anti-RABfor Mouse/Rat/Human |
Record No:11
| ACCESS NO | 100355 |
| GENE | RNF19B (IBRDC3) |
| DESCRIPTION | IBR domain containing 3 |
| NCBI ENTREZ ACCESS NO | 127544 |
| UNIPROT ACCESS NO | Q6ZMZ0 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in cellular assembly and cell-cell interaction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:12
| ACCESS NO | 100416 |
| GENE | RCN1 |
| DESCRIPTION | Reticulocalbin 1 |
| NCBI ENTREZ ACCESS NO | 5954 |
| UNIPROT ACCESS NO | Q15293 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | bronchial epithelial cells stimulated with TGF bet |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is reported to be involved in fibrosis of lungs during pulmonary inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20219718 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RCN1 for Mouse/Human |
Record No:13
| ACCESS NO | 100493 |
| GENE | RPS20 |
| DESCRIPTION | Ribosomal protein S20 |
| NCBI ENTREZ ACCESS NO | 6224 |
| UNIPROT ACCESS NO | P60866 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of glucocorticoid treatment |
| SAMPLE | Bronchial biopsy |
| TECHNIQUES | iTRAQ labelling followed by nano LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is upregulated after budesonide treatment. It is located in cytoplasm. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21939520 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RPS20 for Mouse/Rat/Human |
Record No:14
| ACCESS NO | 100501 |
| GENE | RPL7 |
| DESCRIPTION | Ribosomal protein L7 |
| NCBI ENTREZ ACCESS NO | 6129 |
| UNIPROT ACCESS NO | P18124 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of glucocorticoid treatment |
| SAMPLE | Bronchial biopsy |
| TECHNIQUES | iTRAQ labelling followed by nano LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in translational protein elongation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21939520 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RPL7A [EPR12310] for Mouse/Rat/Human |
Record No:15
| ACCESS NO | 100502 |
| GENE | RPL8 |
| DESCRIPTION | Ribosomal protein L8 |
| NCBI ENTREZ ACCESS NO | 6132 |
| UNIPROT ACCESS NO | P62917 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of glucocorticoid treatment |
| SAMPLE | Bronchial biopsy |
| TECHNIQUES | iTRAQ labelling followed by nano LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is involved in protein synthesis. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21939520 |
| DRUG TARGET | BE0003831 |
| MONCLONAL ANTIBODY | Anti-RPL8 for Mouse/Rat/Human |
Record No:16
| ACCESS NO | 100509 |
| GENE | Retnla |
| DESCRIPTION | Resistin like alpha |
| NCBI ENTREZ ACCESS NO | 57262 |
| UNIPROT ACCESS NO | Q9EP95 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung eosinophil |
| TECHNIQUES | Compugen mouse 22K oligonucleotide microarrays and |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is upregulated in asthma |
| GEO_PRIDE_ACCESS_NO | GSE15345 |
| REFERENCE | 19395375 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:17
| ACCESS NO | 100529 |
| GENE | Retnla |
| DESCRIPTION | Resistin like - alpha |
| NCBI ENTREZ ACCESS NO | 57262 |
| UNIPROT ACCESS NO | Q9EP95 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Macrophages from Broncho Alveolar Lavage (BAL) and |
| TECHNIQUES | Illumina gene chip microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in leukocyte migration into asthmatic airways. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23685352 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:18
| ACCESS NO | 100563 |
| GENE | Rbp4 |
| DESCRIPTION | Retinol-binding protein 4 isoform 1 |
| NCBI ENTREZ ACCESS NO | 19662 |
| UNIPROT ACCESS NO | Q00724 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Tissue from bronchial biopsy |
| TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is a metabolic enzyme. |
| GEO_PRIDE_ACCESS_NO | GSE15823 |
| REFERENCE | 15038835 |
| DRUG TARGET | BE0000314 |
| MONCLONAL ANTIBODY | Anti-RBP4 for Human |
Record No:19
| ACCESS NO | 100608 |
| GENE | Runx3 |
| DESCRIPTION | Runt-related transcription factor 3 |
| NCBI ENTREZ ACCESS NO | 12399 |
| UNIPROT ACCESS NO | Q3U1Q3 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic airway disease |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Methylation-specific PCR and MALDI-TOFÂ |
| OMICS | Epigenetics |
| STUDY | Low Throughput |
| COMMENTS | Negative regulator of allergic disorders but suppressed in progeny due to high methylation if exposed to a methyl rich diet. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18802477 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RUNX1/AML1+RUNX3+RUNX2 for Human/Mouse/Rat |
Record No:20
| ACCESS NO | 100613 |
| GENE | RAD50 |
| DESCRIPTION | RAD50 |
| NCBI ENTREZ ACCESS NO | 10111 |
| UNIPROT ACCESS NO | Q92878 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and asthma and farm exposure |
| SAMPLE | Cord blood |
| TECHNIQUES | bisulphite-specific polymerase chain reaction (PCR |
| OMICS | Epigenetics |
| STUDY | Low Throughput |
| COMMENTS | Hypermethylated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23346934 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RAD50 for Human |
Record No:21
| ACCESS NO | 100693 |
| GENE | Retnlb |
| DESCRIPTION | Retnlb |
| NCBI ENTREZ ACCESS NO | 57263 |
| UNIPROT ACCESS NO | Q99P86 |
| ORGANISM | TSLP TG mice and BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid Broncho Alveol |
| TECHNIQUES | LC-MS/MS and Western blot and qRT PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Plays a role in airway fibrosis and found to be highly upregulated in allergic mouse and were not modulated after dexamethasone treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22837640 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:22
| ACCESS NO | 100700 |
| GENE | Reg3g |
| DESCRIPTION | Regenerating islet-derived 3 gamma |
| NCBI ENTREZ ACCESS NO | 19695 |
| UNIPROT ACCESS NO | O09049 |
| ORGANISM | TSLP TG mice and BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid Broncho Alveol |
| TECHNIQUES | LC-MS/MS and Western blot and qRT PCR |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Regulates keratinocyte proliferation and differentiation after skin injury. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22837640 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:23
| ACCESS NO | 100814 |
| GENE | Racgap1 |
| DESCRIPTION | Rac GTPase activating protein |
| NCBI ENTREZ ACCESS NO | 26934 |
| UNIPROT ACCESS NO | Q9WVM1 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in short time allergen exposure and downregulated in long exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RACGAP1 for Human |
Record No:24
| ACCESS NO | 100815 |
| GENE | Rrm2 |
| DESCRIPTION | Ribonucleoside diphosphate reductase subunit M2 |
| NCBI ENTREZ ACCESS NO | 20135 |
| UNIPROT ACCESS NO | P11157 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in short term and downregulated in long term allergen exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0002450 |
| MONCLONAL ANTIBODY | Anti-RRM2 for Human |
Record No:25
| ACCESS NO | 100935 |
| GENE | Rgs5 |
| DESCRIPTION | Regulator of G-protein signalling 5 |
| NCBI ENTREZ ACCESS NO | 19737 |
| UNIPROT ACCESS NO | O08850 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after induction with food allergens. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RGS5 for Human |
Record No:26
| ACCESS NO | 100956 |
| GENE | RETN |
| DESCRIPTION | Resistin |
| NCBI ENTREZ ACCESS NO | 56729 |
| UNIPROT ACCESS NO | Q9HD89 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in Obese patients |
| SAMPLE | Peripheral Blood mononuclear cells |
| TECHNIQUES | Flow cytometry and immunoflorescent staining |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Synthesised mainly in mononuclear cells facilitates cellular infiltartion and increases the width of fat tissues. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23760409 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Resistin for Human |
Record No:27
| ACCESS NO | 101072 |
| GENE | RNASE3 (ECP) |
| DESCRIPTION | Eosinophil cationic protein |
| NCBI ENTREZ ACCESS NO | 6037 |
| UNIPROT ACCESS NO | P12724 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | BE0000908 |
| MONCLONAL ANTIBODY | N/A |
Record No:28
| ACCESS NO | 101081 |
| GENE | RNASE2 |
| DESCRIPTION | Eosinophil-derived neurotoxin |
| NCBI ENTREZ ACCESS NO | 6036 |
| UNIPROT ACCESS NO | P10153 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and aspirin tolerance |
| SAMPLE | Plasma |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein is present in higher levels in subjects with aspirin exacerbated respiratory disease (AERD) as compared with aspirin tolerant asthma (ATA )subjects. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23805255 |
| DRUG TARGET | BE0001306 |
| MONCLONAL ANTIBODY | N/A |
Record No:29
| ACCESS NO | 101096 |
| GENE | RNASE3 (ECP) |
| DESCRIPTION | Eosinophil cationic protei |
| NCBI ENTREZ ACCESS NO | 6037 |
| UNIPROT ACCESS NO | P12724 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein together with peripheral eosinophil leve is found to be sensitive markers for asthma severity. Patients with shortness in breath can be treated effectively with fluticasone effectively. The effectiveness of treatment can be monitered by significant changes in this biomarker level in serum. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23606983 |
| DRUG TARGET | BE0000908 |
| MONCLONAL ANTIBODY | N/A |
Record No:30
| ACCESS NO | 101124 |
| GENE | RETN |
| DESCRIPTION | Resistin |
| NCBI ENTREZ ACCESS NO | 56729 |
| UNIPROT ACCESS NO | Q9HD89 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Pediatric asthma and Polycyclic aromatic hydrocarbon exposure |
| SAMPLE | Fasting blood |
| TECHNIQUES | Multiplex immunoassay using Luminex 100 system pla |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Exposure to polycyclic hydrocarbon has strong association with increase in serum concentration of this biomarker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23286340 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Resistin for Human |
Record No:31
| ACCESS NO | 101178 |
| GENE | Rela |
| DESCRIPTION | p65 subunit of NF kappa beta |
| NCBI ENTREZ ACCESS NO | 19697 |
| UNIPROT ACCESS NO | Q04207 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effect of a bioactive flavonol Fisetin |
| SAMPLE | Nuclear extracts from lung tissues |
| TECHNIQUES | Immunoflorescence |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Fisetin repressed TNF alpha induced NF kappa B dependent reporter gene expression. This findings implicate a potential therapeutic value of fisetin in the treatment of asthma through negative regulation of NF kappa beta pathway. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22290391 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:32
| ACCESS NO | 101195 |
| GENE | RPS12 |
| DESCRIPTION | 40S ribosomal protein S12 |
| NCBI ENTREZ ACCESS NO | 6206 |
| UNIPROT ACCESS NO | |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be upregulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RPS12 [EPR10963] for Mouse/Rat/Human |
Record No:33
| ACCESS NO | 101220 |
| GENE | RUFY1 |
| DESCRIPTION | RUN and FYVE domain-containing protein 1 |
| NCBI ENTREZ ACCESS NO | 80230 |
| UNIPROT ACCESS NO | Q96T51 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RUFY1 for Human |
Record No:34
| ACCESS NO | 101260 |
| GENE | Rps6kb1 (p70S6K) |
| DESCRIPTION | Polypeptide 1 of ribosomal protein S6 kinase |
| NCBI ENTREZ ACCESS NO | 72508 |
| UNIPROT ACCESS NO | Q8BSK8 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
| SAMPLE | Lung tissue |
| TECHNIQUES | Immunoblot |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Artesunate markedly inhibited the EGF-induced phosphorylation of Akt. Thus EGF induced activation of inflammatory PI3K/Akt signaling pathway is suppressed. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | BE0001193 |
| MONCLONAL ANTIBODY | N/A |
Record No:35
| ACCESS NO | 101262 |
| GENE | Rela (NF-kB) |
| DESCRIPTION | p65 subunit of NF kappa beta |
| NCBI ENTREZ ACCESS NO | 19697 |
| UNIPROT ACCESS NO | Q04207 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
| SAMPLE | Nuclear extracts from lung tissues |
| TECHNIQUES | TransAM NF-kB transcription factor assay kit |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | EGF induced activation of PI3K/Akt signaling pathway causes down stream increase in NF-kB DNA binding activity. Artesunate has been found to decrease the transactivation of this transcription factor. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:36
| ACCESS NO | 101296 |
| GENE | RANTES |
| DESCRIPTION | Chemokine (C-C motif) ligand 5 |
| NCBI ENTREZ ACCESS NO | 6352 |
| UNIPROT ACCESS NO | P13501 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in children |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0000975 |
| MONCLONAL ANTIBODY | Anti-RANTES for Human |
Record No:37
| ACCESS NO | 101342 |
| GENE | RANTES |
| DESCRIPTION | Chemokine (C-C motif) ligand 5 |
| NCBI ENTREZ ACCESS NO | 20304 |
| UNIPROT ACCESS NO | P30882 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Asthma (Effect of andrographolide on NF kappa beta pathway in asthma) |
| SAMPLE | Bronchial Epithelial cells |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Andrographolide suppresed the mRNA expression of RANTES in TNF alpha induced cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19201922 |
| DRUG TARGET | BE0000975 |
| MONCLONAL ANTIBODY | Anti-RANTES for Human |
Record No:38
| ACCESS NO | 101358 |
| GENE | Retnla |
| DESCRIPTION | Fizz1 |
| NCBI ENTREZ ACCESS NO | 57262 |
| UNIPROT ACCESS NO | Q9EP95 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Contributes to airway remodelling through its antiapoptotic properties. Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:39
| ACCESS NO | 101377 |
| GENE | Rps12 |
| DESCRIPTION | Ribosomal protein S12 |
| NCBI ENTREZ ACCESS NO | 20042 |
| UNIPROT ACCESS NO | Q6ZWZ6 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in chronic asthma mouse model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RPS12 for Mouse/Rat/Human |
Record No:40
| ACCESS NO | 101420 |
| GENE | Rgs16 |
| DESCRIPTION | Regulator of G-protein signaling 16 |
| NCBI ENTREZ ACCESS NO | 19734 |
| UNIPROT ACCESS NO | P97428 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RGS16 for Mouse/human |
Record No:41
| ACCESS NO | 101441 |
| GENE | Rasgrp4 |
| DESCRIPTION | RAS guanyl releasing protein 4 |
| NCBI ENTREZ ACCESS NO | 233046 |
| UNIPROT ACCESS NO | Q8BTM9 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3hours and 12 hours of fungal allergen induction in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RASGRP 4 for Human |
Record No:42
| ACCESS NO | 101508 |
| GENE | Rab20 |
| DESCRIPTION | RAB20 member RAS oncogene family |
| NCBI ENTREZ ACCESS NO | 19332 |
| UNIPROT ACCESS NO | P35295 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Rab20 for Human |
Record No:43
| ACCESS NO | 101512 |
| GENE | Relb |
| DESCRIPTION | Avian reticuloendotheliosis viral (v-rel) oncogene related B |
| NCBI ENTREZ ACCESS NO | 19698 |
| UNIPROT ACCESS NO | Q04863 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Rel B for Human |
Record No:44
| ACCESS NO | 101538 |
| GENE | RANTES(CCL5) |
| DESCRIPTION | chemokine (C-C motif) ligand 5 |
| NCBI ENTREZ ACCESS NO | 6352 |
| UNIPROT ACCESS NO | P13501 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by Virus |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Important chemoattractant for eosinophils and overexpressed in virus induced asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17628646 |
| DRUG TARGET | BE0000975 |
| MONCLONAL ANTIBODY | Anti-RANTES for Human |
Record No:45
| ACCESS NO | 101551 |
| GENE | Rantes |
| DESCRIPTION | Chemokine (C-C motif) ligand 5 |
| NCBI ENTREZ ACCESS NO | 20304 |
| UNIPROT ACCESS NO | P30882 |
| ORGANISM | Female Balb/c Mice |
| DISEASE PHENOTYPE | Asthma(Effect of Glycogen synthase kinase-3 beta inhibition on asthma) |
| SAMPLE | Lung tissue |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Involved in delivering eosinophils to the airways. Gsk3b inhibitor blocked the expression of IL8. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17556716 |
| DRUG TARGET | BE0000975 |
| MONCLONAL ANTIBODY | Anti-RANTES for Human |
Record No:46
| ACCESS NO | 101595 |
| GENE | Retnlb |
| DESCRIPTION | Resistin like beta |
| NCBI ENTREZ ACCESS NO | 57263 |
| UNIPROT ACCESS NO | Q99P86 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in secreted signal transduction and expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:47
| ACCESS NO | 101623 |
| GENE | Rex3 |
| DESCRIPTION | Brain expressed gene 1 |
| NCBI ENTREZ ACCESS NO | 19716 |
| UNIPROT ACCESS NO | Q9R224 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:48
| ACCESS NO | 101638 |
| GENE | RHOA |
| DESCRIPTION | Ras homolog family member A |
| NCBI ENTREZ ACCESS NO | 387 |
| UNIPROT ACCESS NO | P61586 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Fibroblasts from Broncho Alveolar Lavage (BAL) Flu |
| TECHNIQUES | MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Involved in cellular migration and overexpressed in mild asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16430780 |
| DRUG TARGET | BE0001190 |
| MONCLONAL ANTIBODY | Anti-RhoA for Human |
Record No:49
| ACCESS NO | 101639 |
| GENE | RAC1 |
| DESCRIPTION | Ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1) |
| NCBI ENTREZ ACCESS NO | 5879 |
| UNIPROT ACCESS NO | P63000 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Fibroblasts from Broncho Alveolar Lavage (BAL) Flu |
| TECHNIQUES | MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed in mild asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16430780 |
| DRUG TARGET | BE0001109 |
| MONCLONAL ANTIBODY | Anti-Rac1for Rat/Rabbit/Human/Mouse |
Record No:50
| ACCESS NO | 101678 |
| GENE | Rela (p65-NFk- B) |
| DESCRIPTION | NF-kappa-B p65 subunit |
| NCBI ENTREZ ACCESS NO | 19697 |
| UNIPROT ACCESS NO | Q04207 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and its protection by IGFBP-3 treatment |
| SAMPLE | Lung tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | Immunoblot |
| OMICS | Proteomics |
| STUDY | Low Throughput |
| COMMENTS | IGFBP-3 degrades p65-NF kappa Beta through IGFBP-3 receptor (IGFBP-3R)-mediated activation of caspases thereby inhibiting TNF- -induced activation of NF- B signaling cascades. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21383009 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-NF-kB p65 [E379] for Mouse/Human |
Record No:51
| ACCESS NO | 101711 |
| GENE | RNASE3 |
| DESCRIPTION | Eosinophil cationic protein polymorphism 3 |
| NCBI ENTREZ ACCESS NO | 6037 |
| UNIPROT ACCESS NO | P12724 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This eosinophilic granule protein is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0000908 |
| MONCLONAL ANTIBODY | N/A |
Record No:52
| ACCESS NO | 101813 |
| GENE | RAN |
| DESCRIPTION | GTP-binding nuclear protein RAN (TC4) |
| NCBI ENTREZ ACCESS NO | 5901 |
| UNIPROT ACCESS NO | P62826 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0004559 |
| MONCLONAL ANTIBODY | Anti-RanGAP1 [EPR3295] for Mouse/Rat/Human |
Record No:53
| ACCESS NO | 101814 |
| GENE | RSU1 |
| DESCRIPTION | Ras suppressor protein 1 (Rsu-1) (RSP-1) |
| NCBI ENTREZ ACCESS NO | 6251 |
| UNIPROT ACCESS NO | Q15404 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RSU1 [EPR16127] for Mouse/Rat/Human |
Record No:54
| ACCESS NO | 101816 |
| GENE | RPS12 |
| DESCRIPTION | 40 S ribosomal protein S12 |
| NCBI ENTREZ ACCESS NO | 6206 |
| UNIPROT ACCESS NO | P25398 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:55
| ACCESS NO | 101896 |
| GENE | RAG1 |
| DESCRIPTION | VJ recombination activating protein 1 |
| NCBI ENTREZ ACCESS NO | 5896 |
| UNIPROT ACCESS NO | P15918 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RAG1 for Mouse/Human |
Record No:56
| ACCESS NO | 101925 |
| GENE | RAB34 |
| DESCRIPTION | Ras-related protein |
| NCBI ENTREZ ACCESS NO | 83871 |
| UNIPROT ACCESS NO | Q9BZG1 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:57
| ACCESS NO | 101948 |
| GENE | RBP7 |
| DESCRIPTION | Retinol binding protein 7 |
| NCBI ENTREZ ACCESS NO | 116362 |
| UNIPROT ACCESS NO | Q96R05 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in asthma.Belongs to the fatty acid binding protein family. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | BE0000532 |
| MONCLONAL ANTIBODY | N/A |
Record No:58
| ACCESS NO | 101988 |
| GENE | RAB22A |
| DESCRIPTION | RAB22A member RAS oncogene family |
| NCBI ENTREZ ACCESS NO | 57403 |
| UNIPROT ACCESS NO | Q9UL26 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in patients with allergic rhinitis with or without asthma in the upper airways. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RAB22A for Mouse/Rat/Human |
Record No:59
| ACCESS NO | 101994 |
| GENE | RBM8A |
| DESCRIPTION | RNA binding motif protein 8A |
| NCBI ENTREZ ACCESS NO | 9939 |
| UNIPROT ACCESS NO | Q9Y5S9 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in the upper airways in patients with allergic rhinitis and asthma. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Y14 for Human |
Record No:60
| ACCESS NO | 102008 |
| GENE | RDH10 |
| DESCRIPTION | Retinol dehydrogenase 10 |
| NCBI ENTREZ ACCESS NO | 157506 |
| UNIPROT ACCESS NO | Q8IZV5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in the lower airways in patients with allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:61
| ACCESS NO | 102010 |
| GENE | RNF141 |
| DESCRIPTION | Ring finger protein 141 |
| NCBI ENTREZ ACCESS NO | 50862 |
| UNIPROT ACCESS NO | Q8WVD5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in the lower airways in patients with allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RNF141 for Human |
Record No:62
| ACCESS NO | 102041 |
| GENE | RIMS2 |
| DESCRIPTION | Regulating synaptic membrane exocytosis 2 |
| NCBI ENTREZ ACCESS NO | 9699 |
| UNIPROT ACCESS NO | Q9UQ26 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:63
| ACCESS NO | 102085 |
| GENE | RAB19B |
| DESCRIPTION | GTP-binding protein RAB19B |
| NCBI ENTREZ ACCESS NO | 401409 |
| UNIPROT ACCESS NO | A4D1S5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in protein trafficking. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RAB19B for Human |
Record No:64
| ACCESS NO | 102086 |
| GENE | RAB27B |
| DESCRIPTION | RAB27B member RAS oncogene |
| NCBI ENTREZ ACCESS NO | 5874 |
| UNIPROT ACCESS NO | O00194 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Activated in asthma. Involved in protein trafficking and expressed in Th2 cells. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:65
| ACCESS NO | 102087 |
| GENE | RAB30 |
| DESCRIPTION | RAB30 member RAS oncogene family |
| NCBI ENTREZ ACCESS NO | 27314 |
| UNIPROT ACCESS NO | Q15771 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Activated in asthma. Involved in protein trafficking and expressed in Th2 cells. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RAB30 for Mouse/Rat/Human |
Record No:66
| ACCESS NO | 102095 |
| GENE | RAP2B |
| DESCRIPTION | RAP2B member of RAS oncogene family |
| NCBI ENTREZ ACCESS NO | 5912 |
| UNIPROT ACCESS NO | P61225 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in RAS signalling and calcium signalling. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RAP2B for Mouse/Human |
Record No:67
| ACCESS NO | 102096 |
| GENE | RASL11A |
| DESCRIPTION | RAS-like family 11 member A |
| NCBI ENTREZ ACCESS NO | 387496 |
| UNIPROT ACCESS NO | Q6T310 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in tumour supressing activity. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:68
| ACCESS NO | 102107 |
| GENE | RAP1A |
| DESCRIPTION | RAP1A member of RAS oncogene family |
| NCBI ENTREZ ACCESS NO | 5906 |
| UNIPROT ACCESS NO | P62834 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in TCR pathway. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RAP1A for Human |
Record No:69
| ACCESS NO | 102115 |
| GENE | RRS1 |
| DESCRIPTION | RRS1 ribosome biogenesis regulator homolog |
| NCBI ENTREZ ACCESS NO | 23212 |
| UNIPROT ACCESS NO | Q15050 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentialy expressed in asthma. Involved in high level cytokine production. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |