BROWSE RESULT OF S
203 Records |
ACCESS NO | 100001 |
GENE | S100A8 |
DESCRIPTION | S100 calcium binding protein A8 |
NCBI ENTREZ ACCESS NO | 6279 |
UNIPROT ACCESS NO | P05109 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
SAMPLE | CD2+ cells |
TECHNIQUES | Microarray and TaqMan Gene Expression Assays |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It has chemotactic effects on leucocytes and proinflammatory effects on endothelial cells. |
GEO_PRIDE_ACCESS_NO | GSE7894 |
REFERENCE | 19001005 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-MRP8 + MRP14 for Human/Monkey |
Record No:2
ACCESS NO | 100016 |
GENE | SOD2 |
DESCRIPTION | superoxide dismutase 2 |
NCBI ENTREZ ACCESS NO | 6648 |
UNIPROT ACCESS NO | P04179 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
SAMPLE | CD2+ cells |
TECHNIQUES | Microarray and TaqMan Gene Expression Assays |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is a stress responsive protein. It recruits and activates immune cells and thus prolonging inflammation. |
GEO_PRIDE_ACCESS_NO | GSE7894 |
REFERENCE | 19001005 |
DRUG TARGET | BE0004453 |
MONCLONAL ANTIBODY | Anti-SOD2 for Mouse/Rat/Human |
Record No:3
ACCESS NO | 100017 |
GENE | S100A9 |
DESCRIPTION | S100 calcium binding protein A9 |
NCBI ENTREZ ACCESS NO | 6280 |
UNIPROT ACCESS NO | P06702 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
SAMPLE | CD2+ cells |
TECHNIQUES | Microarray and TaqMan Gene Expression Assays |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is involved in immune response and inflammation. It has chemotactic effects on leucocytes and proinflammatory effects on endothelial cells. |
GEO_PRIDE_ACCESS_NO | GSE7894 |
REFERENCE | 19001005 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-S100A9 for Human |
Record No:4
ACCESS NO | 100022 |
GENE | S100A12 |
DESCRIPTION | S100 calcium binding protein A12 |
NCBI ENTREZ ACCESS NO | 6283 |
UNIPROT ACCESS NO | P80511 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
SAMPLE | CD2+ cells |
TECHNIQUES | Microarray and TaqMan Gene Expression Assays |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is a stress responsive protein. It recruits and activates immune cells and thus prolonging inflammation. |
GEO_PRIDE_ACCESS_NO | GSE7894 |
REFERENCE | 19001005 |
DRUG TARGET | BE0001206 |
MONCLONAL ANTIBODY | Anti-S100A12 for Human |
Record No:5
ACCESS NO | 100025 |
GENE | SELT |
DESCRIPTION | Selenoprotein T |
NCBI ENTREZ ACCESS NO | 51714 |
UNIPROT ACCESS NO | P62341 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
SAMPLE | CD2+ cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene is upregulated more in low SEC group. |
GEO_PRIDE_ACCESS_NO | GSE7894 |
REFERENCE | 19001005 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:6
ACCESS NO | 100027 |
GENE | SAMSN1 |
DESCRIPTION | SAM domain and SH3 domain and nuclear localization signals 1 |
NCBI ENTREZ ACCESS NO | 64092 |
UNIPROT ACCESS NO | Q9NSI8 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
SAMPLE | CD2+ cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene is upregulated more in low SEC group. |
GEO_PRIDE_ACCESS_NO | GSE7894 |
REFERENCE | 19001005 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SAMSN1 for Human |
Record No:7
ACCESS NO | 100082 |
GENE | SPARC |
DESCRIPTION | Secreted protein cysteine-rich (osteonectin) |
NCBI ENTREZ ACCESS NO | 6678 |
UNIPROT ACCESS NO | P09486 |
ORGANISM | Human |
DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | Microarray and qRT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is involved in innate immunity. |
GEO_PRIDE_ACCESS_NO | GSE16032 |
REFERENCE | 19620293 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SPARC for Human/Rat |
Record No:8
ACCESS NO | 100110 |
GENE | Scin |
DESCRIPTION | Scinderin |
NCBI ENTREZ ACCESS NO | 20259 |
UNIPROT ACCESS NO | Q60604 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | DNA Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | It codes for an actin binding protein induced by IL-13 and not by IL-4. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19249085 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:9
ACCESS NO | 100112 |
GENE | Serpina3g |
DESCRIPTION | Serine (or cysteine) peptidase inhibitor - clade A - member 3G |
NCBI ENTREZ ACCESS NO | 20715 |
UNIPROT ACCESS NO | Q5I2A0 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | DNA Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This arginine metabolism is commonly induced by allergens and Th2 cytokines such as IL-4 and IL-13. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19249085 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:10
ACCESS NO | 100139 |
GENE | Slc5a1 |
DESCRIPTION | Solute carrier family 5 (sodium/glucose cotransporter) member 1 |
NCBI ENTREZ ACCESS NO | 20537 |
UNIPROT ACCESS NO | Q8C3K6 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | DNA Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | This is an IL-13 specific ion transporter induced in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19249085 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SLC5A10 for Mouse/Rat/Human |
Record No:11
ACCESS NO | 100141 |
GENE | Sprr2a (Sprr2a1) |
DESCRIPTION | Small proline-rich protein 2A |
NCBI ENTREZ ACCESS NO | 20755 |
UNIPROT ACCESS NO | Q4KL71 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | DNA Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | This is an IL-13 specific epithelial product induced in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19249085 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:12
ACCESS NO | 100149 |
GENE | STC1 |
DESCRIPTION | Stanniocalcin 1 |
NCBI ENTREZ ACCESS NO | 6781 |
UNIPROT ACCESS NO | P52823 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Stanniocalcin 1 for Rat/Human |
Record No:13
ACCESS NO | 100160 |
GENE | S100A9 |
DESCRIPTION | Calgranulin B - S100 calcium binding protein A9 |
NCBI ENTREZ ACCESS NO | 6280 |
UNIPROT ACCESS NO | P06702 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-S100A9 for Human |
Record No:14
ACCESS NO | 100161 |
GENE | SLIT2 |
DESCRIPTION | Slit homolog 2 (Drosophila) |
NCBI ENTREZ ACCESS NO | 9353 |
UNIPROT ACCESS NO | O94813 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Slit2 for Mouse/Rat/Human |
Record No:15
ACCESS NO | 100172 |
GENE | SPRY4 |
DESCRIPTION | Sprouty homolog 4 |
NCBI ENTREZ ACCESS NO | 81848 |
UNIPROT ACCESS NO | Q9C004 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:16
ACCESS NO | 100184 |
GENE | SELENBP1 |
DESCRIPTION | Selenium binding protein 1 |
NCBI ENTREZ ACCESS NO | 8991 |
UNIPROT ACCESS NO | Q13228 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is a immunity and defense related protein significantly down regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Selenium Binding Protein 1 for Human |
Record No:17
ACCESS NO | 100189 |
GENE | SCARA3 |
DESCRIPTION | Scavenger receptor class A member 3 |
NCBI ENTREZ ACCESS NO | 51435 |
UNIPROT ACCESS NO | Q6AZY7 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray and qPCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | This is a receptor protein significantly down regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SCARA3 for Mouse/Human |
Record No:18
ACCESS NO | 100190 |
GENE | SERPINE2 |
DESCRIPTION | Serine proteinase inhibitor - clade E member 2 |
NCBI ENTREZ ACCESS NO | 5270 |
UNIPROT ACCESS NO | P07093 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray and qPCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | This is an enzyme inhibitory protein significantly up regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SERPINE2 for Rat/Mouse |
Record No:19
ACCESS NO | 100191 |
GENE | SERPINB4 |
DESCRIPTION | Serine proteinase inhibitor - clade B member 4 |
NCBI ENTREZ ACCESS NO | 6318 |
UNIPROT ACCESS NO | P48594 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is an enzyme inhibitory protein significantly up regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SERPINB4 for Human |
Record No:20
ACCESS NO | 100192 |
GENE | SERPINB8 |
DESCRIPTION | Serine proteinase inhibitor - clade B member 8 |
NCBI ENTREZ ACCESS NO | 5271 |
UNIPROT ACCESS NO | P50452 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is an enzyme inhibitory protein significantly up regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:21
ACCESS NO | 100194 |
GENE | SERPINF1 |
DESCRIPTION | Serine proteinase inhibitor - clade F member 1 |
NCBI ENTREZ ACCESS NO | 5176 |
UNIPROT ACCESS NO | P36955 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray and qPCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | This is an enzyme inhibitory protein significantly down regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-PEDF for Human |
Record No:22
ACCESS NO | 100200 |
GENE | SEMA6D |
DESCRIPTION | Semaphorin 6D |
NCBI ENTREZ ACCESS NO | 80031 |
UNIPROT ACCESS NO | Q8NFY4 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is an transcription factor significantly downregulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:23
ACCESS NO | 100203 |
GENE | SUV420H2 |
DESCRIPTION | Suppressor of variegation 4-20 homolog 2 (Drosophila) |
NCBI ENTREZ ACCESS NO | 84787 |
UNIPROT ACCESS NO | Q86Y97 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene codes for a metabolic enzyme significantly up regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | BE0002123 |
MONCLONAL ANTIBODY | N/A |
Record No:24
ACCESS NO | 100216 |
GENE | SLCO4A1 |
DESCRIPTION | Solute carrier organic anion transporter family member 4A1 |
NCBI ENTREZ ACCESS NO | 28231 |
UNIPROT ACCESS NO | Q96BD0 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene codes for a transporter significantly up regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:25
ACCESS NO | 100217 |
GENE | SLC7A11 |
DESCRIPTION | Solute carrier family 7 member 11 |
NCBI ENTREZ ACCESS NO | 23657 |
UNIPROT ACCESS NO | Q9UPY5 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene codes for a transporter significantly up regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:26
ACCESS NO | 100224 |
GENE | SLC40A1 |
DESCRIPTION | Solute carrier family 40 member 1 |
NCBI ENTREZ ACCESS NO | 30061 |
UNIPROT ACCESS NO | Q9NP59 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene codes for a calcium binding protein significantly down regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SLC40A1 for Mouse/Human |
Record No:27
ACCESS NO | 100225 |
GENE | SHISA2 (TMEM46) |
DESCRIPTION | Transmembrane protein 46 |
NCBI ENTREZ ACCESS NO | 387914 |
UNIPROT ACCESS NO | Q6UWI4 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene is significantly up regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:28
ACCESS NO | 100227 |
GENE | SYNGR3 |
DESCRIPTION | Synaptogyrin 3 |
NCBI ENTREZ ACCESS NO | 9143 |
UNIPROT ACCESS NO | O43761 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene is significantly down regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:29
ACCESS NO | 100228 |
GENE | SNCA |
DESCRIPTION | Synuclein - alpha |
NCBI ENTREZ ACCESS NO | 6622 |
UNIPROT ACCESS NO | P37840 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene is significantly down regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-alpha Synuclein for Rat/Human |
Record No:30
ACCESS NO | 100236 |
GENE | SCEL |
DESCRIPTION | Sciellin |
NCBI ENTREZ ACCESS NO | 8796 |
UNIPROT ACCESS NO | O95171 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene is significantly up regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:31
ACCESS NO | 100238 |
GENE | SAMD5 |
DESCRIPTION | SAM domain containing 1 |
NCBI ENTREZ ACCESS NO | 389432 |
UNIPROT ACCESS NO | Q5TGI4 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
SAMPLE | Human airway epithelial cell |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene is significantly down regulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:32
ACCESS NO | 100250 |
GENE | SERPINB2 |
DESCRIPTION | Serpin peptidase inhibitor-clade B (ovalbumin) member2 |
NCBI ENTREZ ACCESS NO | 5055 |
UNIPROT ACCESS NO | P05120 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
SAMPLE | Primary bronchial epithelial cells |
TECHNIQUES | Affymetrix GeneChip Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | It acts as an inflammatory factor. |
GEO_PRIDE_ACCESS_NO | GSE13396 |
REFERENCE | 19710636 |
DRUG TARGET | BE0000969 |
MONCLONAL ANTIBODY | Anti-SerpinB2 for Human |
Record No:33
ACCESS NO | 100255 |
GENE | SPRR2B |
DESCRIPTION | Small proline-rich protein 2B |
NCBI ENTREZ ACCESS NO | 6701 |
UNIPROT ACCESS NO | P35325 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
SAMPLE | Primary bronchial epithelial cells |
TECHNIQUES | Affymetrix GeneChip Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is a structural protein involved in airway remodelling. |
GEO_PRIDE_ACCESS_NO | GSE13396 |
REFERENCE | 19710636 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:34
ACCESS NO | 100259 |
GENE | S100A3 |
DESCRIPTION | S100 calcium binding protein A3 |
NCBI ENTREZ ACCESS NO | 6274 |
UNIPROT ACCESS NO | P33764 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
SAMPLE | Primary bronchial epithelial cells |
TECHNIQUES | Affymetrix GeneChip Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This calcium and zinc binding protein shows upregulation after rhinovirus infection in the asthma group. |
GEO_PRIDE_ACCESS_NO | GSE13396 |
REFERENCE | 19710636 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:35
ACCESS NO | 100260 |
GENE | SOCS3 |
DESCRIPTION | Suppressor of cytokine signaling 3 |
NCBI ENTREZ ACCESS NO | 9021 |
UNIPROT ACCESS NO | O14543 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
SAMPLE | Primary bronchial epithelial cells |
TECHNIQUES | Affymetrix GeneChip Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene shows upregulation in asthma patients and as well as in non-asthmatic normal subjects infected with rhino virus. |
GEO_PRIDE_ACCESS_NO | GSE13396 |
REFERENCE | 19710636 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SOCS3 for rat/Human |
Record No:36
ACCESS NO | 100273 |
GENE | SPARC |
DESCRIPTION | Secreted protein-acidic-cysteine-rich (osteonectin) |
NCBI ENTREZ ACCESS NO | 6678 |
UNIPROT ACCESS NO | P09486 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
SAMPLE | Primary bronchial epithelial cells |
TECHNIQUES | Affymetrix GeneChip Microarray and qRT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is involved in airway repair and remodelling. |
GEO_PRIDE_ACCESS_NO | GSE13396 |
REFERENCE | 19710636 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:37
ACCESS NO | 100275 |
GENE | SVIL |
DESCRIPTION | Supervillin |
NCBI ENTREZ ACCESS NO | 6840 |
UNIPROT ACCESS NO | O95425 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | It is upregulated in asthma exacerbation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19187333 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:38
ACCESS NO | 100276 |
GENE | S100A9 |
DESCRIPTION | S100 calcium binding protein A9 |
NCBI ENTREZ ACCESS NO | 6280 |
UNIPROT ACCESS NO | P06702 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | Illumina Human Ref8 BeadChip arrays and real time |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is an infection related gene upregulated in asthma exacerbation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19187333 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-S100A9 for Human |
Record No:39
ACCESS NO | 100300 |
GENE | Stambp (AMSH) |
DESCRIPTION | STAM-associated protein |
NCBI ENTREZ ACCESS NO | 70527 |
UNIPROT ACCESS NO | Q9CQ26 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
SAMPLE | Peripheral blood monocytes |
TECHNIQUES | DNA Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This protein is involved in cytokine signaling and secretion. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20840155 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-STAMBPL1 for Human |
Record No:40
ACCESS NO | 100303 |
GENE | Socs6 |
DESCRIPTION | Suppressor of cytokine signaling 6 |
NCBI ENTREZ ACCESS NO | 54607 |
UNIPROT ACCESS NO | Q9JLY0 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
SAMPLE | Peripheral blood monocytes |
TECHNIQUES | DNA Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This protein is involved in Cytokine signaling. It has been observed to be down regulated in the present study. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20840155 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SOCS6 for Human |
Record No:41
ACCESS NO | 100306 |
GENE | Spock1 |
DESCRIPTION | TESTICAN-1 |
NCBI ENTREZ ACCESS NO | 20745 |
UNIPROT ACCESS NO | Q62288 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
SAMPLE | Peripheral blood monocytes |
TECHNIQUES | DNA Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This is an extracellular matrix protein. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20840155 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:42
ACCESS NO | 100326 |
GENE | S100a9 |
DESCRIPTION | S100 calcium-binding protein A9 |
NCBI ENTREZ ACCESS NO | 94195 |
UNIPROT ACCESS NO | P50116 |
ORGANISM | Rat |
DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
SAMPLE | Lung tissue |
TECHNIQUES | Serial analysis of gene expression (SAGE) and qRT- |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is highly expressed in neutrophils and monocytes. It is present at high levels in the extracellular milieu during inflammatory conditions but its extracellular function remains unclear. Inhibition of the S100A8 and S100A9 proteins prior to intranasal allergen challenge in mice resulted in preservation of all the characteristics of the asthma phenotype but there was a significant reduction in the number of eosinophils in BAL fluid. |
GEO_PRIDE_ACCESS_NO | GSE2475 |
REFERENCE | 18922145 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-S100A9 for Human |
Record No:43
ACCESS NO | 100331 |
GENE | Serpinc1 |
DESCRIPTION | Serine (or cysteine) proteinase inhibitor clade C |
NCBI ENTREZ ACCESS NO | 11905 |
UNIPROT ACCESS NO | P32261 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma induced chemicals |
SAMPLE | Serum |
TECHNIQUES | 2D DIGE and MALDI-TOF-MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It is known to exert anti-inflammatory effects. In this study It is downregulated in serum of TDI-treated mice suggesting these mice are less able to cope with the neutrophilic inflammation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20860378 |
DRUG TARGET | BE0000280 |
MONCLONAL ANTIBODY | Anti-Antithrombin III for Mouse/Rat/Human |
Record No:44
ACCESS NO | 100361 |
GENE | Sptan1 |
DESCRIPTION | alpha-spectrin 2 |
NCBI ENTREZ ACCESS NO | 64159 |
UNIPROT ACCESS NO | P16086 |
ORGANISM | Rat |
DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
SAMPLE | Lung tissue |
TECHNIQUES | Serial analysis of gene expression (SAGE) |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | It is involved in the regulation of tight junction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18922145 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Alpha Fodrin [D8B7] for Mouse/Rat/Human |
Record No:45
ACCESS NO | 100380 |
GENE | Sftpa1 |
DESCRIPTION | Pulmonary surfactant-associated protein D |
NCBI ENTREZ ACCESS NO | 20387 |
UNIPROT ACCESS NO | P35242 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
SAMPLE | Broncho Alveolar Lavage (BAL)F |
TECHNIQUES | 2D PAGE andLC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This gene is upregulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20029843 |
DRUG TARGET | BE0004481 |
MONCLONAL ANTIBODY | Anti-Surfactant Protein A for Human |
Record No:46
ACCESS NO | 100391 |
GENE | Sftpd |
DESCRIPTION | Pulmonary surfactant-associated protein D (PSP-D) |
NCBI ENTREZ ACCESS NO | 20390 |
UNIPROT ACCESS NO | P50404 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
SAMPLE | Broncho Alveolar Lavage (BAL)F |
TECHNIQUES | 2D PAGE andLC-MS/MS followed by western blot and r |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is known to play an important role in the innate immunity of mucosal surfaces and especially in lungs by protecting against inhaled microorganisms and allergen challenges. It is important in regulating allergic responses. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20029843 |
DRUG TARGET | BE0001107 |
MONCLONAL ANTIBODY | Anti-Surfactant protein D for Mouse/Human/Rat |
Record No:47
ACCESS NO | 100403 |
GENE | SERPINA3 |
DESCRIPTION | alpha 1-Antichymotrypsin |
NCBI ENTREZ ACCESS NO | 102142784 |
UNIPROT ACCESS NO | N/A |
ORGANISM | Monkey |
DISEASE PHENOTYPE | Allergic asthma |
SAMPLE | Lung tissue |
TECHNIQUES | DNA microarrays and Quantitative RT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It inhibits the neutrophil cathepsin G and mast cell chymases. In this way it protects the lower respiratory tract from damage by proteolytic enzymes. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 12049661 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-alpha 1 Antichymotrypsin for Human |
Record No:48
ACCESS NO | 100407 |
GENE | SOD2 |
DESCRIPTION | Mn superoxide dismutase |
NCBI ENTREZ ACCESS NO | 102123902 |
UNIPROT ACCESS NO | Q8HXP3 |
ORGANISM | Monkey |
DISEASE PHENOTYPE | Allergic asthma |
SAMPLE | Lung tissue |
TECHNIQUES | DNA microarrays and Quantitative RT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is involved in tissue remodeling. It is significantly modulated by IL4. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 12049661 |
DRUG TARGET | BE0004453 |
MONCLONAL ANTIBODY | Anti-SOD2 [2A1] for Mouse/Rat/Human |
Record No:49
ACCESS NO | 100410 |
GENE | SERPINE1 |
DESCRIPTION | Plasminogen activator inhibitor-1 |
NCBI ENTREZ ACCESS NO | 102147003 |
UNIPROT ACCESS NO | B3TZE1 |
ORGANISM | Monkey |
DISEASE PHENOTYPE | Allergic asthma |
SAMPLE | Lung tissue |
TECHNIQUES | DNA microarrays and Quantitative RT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is involved in tissue repair and remodelling. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 12049661 |
DRUG TARGET | BE000240 |
MONCLONAL ANTIBODY | Anti-PAI1 for Human |
Record No:50
ACCESS NO | 100413 |
GENE | SRSF1 |
DESCRIPTION | Alternative splicing factor ASF-2 |
NCBI ENTREZ ACCESS NO | 6426 |
UNIPROT ACCESS NO | Q07955 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Bronchial epithelial cells stimulated with leukotr |
TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | LTE4 and TGF beta1 alone or together with this gene may be able to hinder alternative splicing in bronchial epithelial cells. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20219718 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SF2 for Mouse/Rat/Human |
Record No:51
ACCESS NO | 100420 |
GENE | STMN1 |
DESCRIPTION | Stathmin 1 |
NCBI ENTREZ ACCESS NO | 3925 |
UNIPROT ACCESS NO | P16949 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | bronchial epithelial cells stimulated with TGF bet |
TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It controls TGF beta1 mediated regulation of proliferation of bronchial epithelial cells by participation in the construction and function of the mitotic spindle . |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20219718 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Stathmin 1 for Mouse/Rat/Human |
Record No:52
ACCESS NO | 100421 |
GENE | SOD1 |
DESCRIPTION | Superoxide dismutase 1 |
NCBI ENTREZ ACCESS NO | 6647 |
UNIPROT ACCESS NO | P00441 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | bronchial epithelial cells stimulated with TGF bet |
TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Upregulation of this metal dependent antioxidant enzyme causes TGF beta 1 to potentially increase the bronchial epithelial cells' ability to withstand oxidative stress. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20219718 |
DRUG TARGET | BE0002390 |
MONCLONAL ANTIBODY | Anti-Superoxide Dismutase 1 for Human |
Record No:53
ACCESS NO | 100430 |
GENE | SFN |
DESCRIPTION | Stratifin |
NCBI ENTREZ ACCESS NO | 2810 |
UNIPROT ACCESS NO | P13693 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | bronchial epithelial cells stimulated with TGF bet |
TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It is downregulated in asthma inflammation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20219718 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-14-3-3 sigma for Mouse/Human |
Record No:54
ACCESS NO | 100434 |
GENE | S100A9 |
DESCRIPTION | S100 calcium-binding protein A9 |
NCBI ENTREZ ACCESS NO | 6280 |
UNIPROT ACCESS NO | P06702 |
ORGANISM | Human |
DISEASE PHENOTYPE | Severe asthma |
SAMPLE | CD4 + T cells |
TECHNIQUES | Microarray and Real time Q-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is upregulated in asthma inflammation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21917308 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-S100A9Â for Human |
Record No:55
ACCESS NO | 100435 |
GENE | S100A8 |
DESCRIPTION | S100 calcium-binding protein A8 |
NCBI ENTREZ ACCESS NO | 6279 |
UNIPROT ACCESS NO | P05109 |
ORGANISM | Human |
DISEASE PHENOTYPE | Severe asthma |
SAMPLE | CD4 + T cells |
TECHNIQUES | Microarray and Real time Q-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is upregulated in asthma inflammation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21917308 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-MRP8 + MRP14 for Human |
Record No:56
ACCESS NO | 100437 |
GENE | S100A12 |
DESCRIPTION | S100 calcium-binding protein A12 |
NCBI ENTREZ ACCESS NO | 6283 |
UNIPROT ACCESS NO | P80511 |
ORGANISM | Human |
DISEASE PHENOTYPE | Severe asthma |
SAMPLE | CD4 + T cells |
TECHNIQUES | Microarray and Real time Q-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is upregulated in asthma inflammation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21917308 |
DRUG TARGET | BE0001206 |
MONCLONAL ANTIBODY | Anti-S100A12 for Human |
Record No:57
ACCESS NO | 100438 |
GENE | S100P |
DESCRIPTION | S100 calcium-binding protein P |
NCBI ENTREZ ACCESS NO | 6286 |
UNIPROT ACCESS NO | P25815 |
ORGANISM | Human |
DISEASE PHENOTYPE | Severe asthma |
SAMPLE | CD4 + T cells |
TECHNIQUES | Microarray and Real time Q-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is upregulated in asthma inflammation. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21917308 |
DRUG TARGET | BE0001191 |
MONCLONAL ANTIBODY | Anti-S100P for Human |
Record No:58
ACCESS NO | 100457 |
GENE | SERPINB4 |
DESCRIPTION | Serpin peptidase inhibitor-clade B (ovalbumin)-member 4 |
NCBI ENTREZ ACCESS NO | 6318 |
UNIPROT ACCESS NO | P48594 |
ORGANISM | Human |
DISEASE PHENOTYPE | Respiratory Allergy |
SAMPLE | Nasal Epithelial Cell |
TECHNIQUES | Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This Th2 induced gene is upregulated upon dust mite allergen challenge. |
GEO_PRIDE_ACCESS_NO | GSE19190 |
REFERENCE | 22005912 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SERPINB4 for Human |
Record No:59
ACCESS NO | 100494 |
GENE | SERPINB3 |
DESCRIPTION | Serpin peptidase inhibitor clade B (ovalbumin) member 3 |
NCBI ENTREZ ACCESS NO | 6317 |
UNIPROT ACCESS NO | P29508 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and effect of glucocorticoid treatment |
SAMPLE | Bronchial biopsy |
TECHNIQUES | iTRAQ labelling followed by nano LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It is upregulated after budesonide treatment. It is located in extracellular space. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21939520 |
DRUG TARGET | BE0004463 |
MONCLONAL ANTIBODY | Anti-SerpinB3 for Human |
Record No:60
ACCESS NO | 100505 |
GENE | SERPINB2 |
DESCRIPTION | Serine peptidase inhibitor clade B member 2 |
NCBI ENTREZ ACCESS NO | 5055 |
UNIPROT ACCESS NO | P05120 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and corticosteroids treatment |
SAMPLE | Airway epithelial cells |
TECHNIQUES | microarray-Affymetrix and q-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It is a member of the serpin class of proteases. It functions to inhibit plasminogen activation and promote fibrin formation and depositionformation and deposition |
GEO_PRIDE_ACCESS_NO | GSE4302 |
REFERENCE | 17898169 |
DRUG TARGET | BE0000969 |
MONCLONAL ANTIBODY | N/A |
Record No:61
ACCESS NO | 100507 |
GENE | SCNN1G |
DESCRIPTION | Sodium channel non-voltage-gated-1 gamma subunit |
NCBI ENTREZ ACCESS NO | 6340 |
UNIPROT ACCESS NO | P51170 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and corticosteroids treatment |
SAMPLE | Airway epithelial cells |
TECHNIQUES | microarray-Affymetrix |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | sodium channels controlling fluid and electrolyte transport across pulmonary epithelia |
GEO_PRIDE_ACCESS_NO | GSE4302 |
REFERENCE | 17898169 |
DRUG TARGET | DB00384; DB00594 |
MONCLONAL ANTIBODY | N/A |
Record No:62
ACCESS NO | 100514 |
GENE | Socs1 |
DESCRIPTION | Suppressor of cytokine signaling 1 |
NCBI ENTREZ ACCESS NO | 12703 |
UNIPROT ACCESS NO | O35716 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma and role of Galectin-4 |
SAMPLE | Lung tissue |
TECHNIQUES | Microarray-affymetrix + Real time RT PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | maintain the balance between Th2 and Th1 |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21547260 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:63
ACCESS NO | 100515 |
GENE | Socs3 |
DESCRIPTION | Suppressor of cytokine signaling 1 |
NCBI ENTREZ ACCESS NO | 12702 |
UNIPROT ACCESS NO | O35718 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma and role of Galectin-4 |
SAMPLE | Lung tissue |
TECHNIQUES | Microarray-affymetrix + Real time RT PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | maintain the balance between Th2 and Th1 |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21547260 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SOCS3 for Human/Rat |
Record No:64
ACCESS NO | 100518 |
GENE | SPP1 |
DESCRIPTION | Osteopontin |
NCBI ENTREZ ACCESS NO | 6696 |
UNIPROT ACCESS NO | P10451 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergy |
SAMPLE | CD4+ T cell |
TECHNIQUES | RT PCR and microarray-affymetrix |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Osteopontin regulates apoptosis and may influence the Th1/Th2 balance |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18269679 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Osteopontin for Human/Mouse |
Record No:65
ACCESS NO | 100537 |
GENE | Slpi |
DESCRIPTION | Secretory leukocyte peptidase inhibitor |
NCBI ENTREZ ACCESS NO | 20568 |
UNIPROT ACCESS NO | P97430 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Acute and chronic asthma |
SAMPLE | Tissue from left lung |
TECHNIQUES | Affymetrix gene chip cDNA microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene is responsible for extracellular matrix remodelling. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18087161 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SLP1 for Human |
Record No:66
ACCESS NO | 100546 |
GENE | Scd1 |
DESCRIPTION | Stearoyl-coenzyme A desaturated 1 |
NCBI ENTREZ ACCESS NO | 246074 |
UNIPROT ACCESS NO | P07308 |
ORGANISM | Norway brown rat |
DISEASE PHENOTYPE | Allergic asthma |
SAMPLE | Right cranial lung lobe |
TECHNIQUES | Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This gene shows greatest increase in expression level. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19176365 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SCD1 for Mouse/Rat/Human |
Record No:67
ACCESS NO | 100572 |
GENE | S100A9 |
DESCRIPTION | S100 calcium binding protein A9(Calgranulin B) |
NCBI ENTREZ ACCESS NO | 6280 |
UNIPROT ACCESS NO | P06702 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Allergic inflammation |
SAMPLE | Bronchoalveolar lavage fluid |
TECHNIQUES | 2D PAGE and MALDI-TOF-MS; real-time PCR |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | A small calcium binding protein involved in neutrophil chemotaxis and adhesion. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17082650 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-S100A9 for Human |
Record No:68
ACCESS NO | 100573 |
GENE | SOD1 |
DESCRIPTION | Superoxide dismutase |
NCBI ENTREZ ACCESS NO | 6647 |
UNIPROT ACCESS NO | P00441 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Allergic inflammation |
SAMPLE | Bronchoalveolar lavage fluid |
TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Expressed in alveolar macrophages and are antioxidants scavengers. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17082650 |
DRUG TARGET | BE0002390 |
MONCLONAL ANTIBODY | Anti-Superoxide Dismutase 1 for Human |
Record No:69
ACCESS NO | 100585 |
GENE | SERPINA1 |
DESCRIPTION | Alpha1-Antitrypsin |
NCBI ENTREZ ACCESS NO | 5265 |
UNIPROT ACCESS NO | P01009 |
ORGANISM | Human |
DISEASE PHENOTYPE | Seasonal allergic rhinitis |
SAMPLE | Nasal Lavage Fluid |
TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Inhibitor of serine protease and inactivates proteolytic enzymes such as elastase thus providing defense to the host. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16457599 |
DRUG TARGET | BE0000952 |
MONCLONAL ANTIBODY | Anti-SERPINA10 for Human |
Record No:70
ACCESS NO | 100597 |
GENE | SFTPB |
DESCRIPTION | surfactant protein |
NCBI ENTREZ ACCESS NO | 6439 |
UNIPROT ACCESS NO | P07988 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Broncho Alveolar Lavage (BAL)F |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Synthesized by lung epithelial cells and participates in early defense against pathogens. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Surfactant protein B for Human/Mouse |
Record No:71
ACCESS NO | 100599 |
GENE | S100A9 |
DESCRIPTION | Calgranulin B |
NCBI ENTREZ ACCESS NO | 6280 |
UNIPROT ACCESS NO | P06702 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Broncho Alveolar Lavage (BAL)F |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Expression significantly increased after allergen challenge. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-S100A9 for Human |
Record No:72
ACCESS NO | 100623 |
GENE | SCGB3A1 |
DESCRIPTION | secretoglobin family 3A member 1 |
NCBI ENTREZ ACCESS NO | 92304 |
UNIPROT ACCESS NO | Q96QR1 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and its treatment with corticosteroids |
SAMPLE | Airway epithelial cells |
TECHNIQUES | Microarray-Affymetrix and real time PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Downregulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | GSE4302 |
REFERENCE | 17898169 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:73
ACCESS NO | 100628 |
GENE | SERPIN B3 |
DESCRIPTION | Serpin peptidase inhibitor - clade B |
NCBI ENTREZ ACCESS NO | 6317 |
UNIPROT ACCESS NO | P29508 |
ORGANISM | Human |
DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
SAMPLE | Nasal fluid |
TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Upregulated in bronchial epithelial cells in asthma patients and significantly decreased after glucocorticoid treatment. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21887273 |
DRUG TARGET | BE0004463 |
MONCLONAL ANTIBODY | Anti-SerpinB3 for Human |
Record No:74
ACCESS NO | 100635 |
GENE | SCGB1D2 |
DESCRIPTION | Secretoglobin family 1D member 2 |
NCBI ENTREZ ACCESS NO | 10647 |
UNIPROT ACCESS NO | O95969 |
ORGANISM | Human |
DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
SAMPLE | Nasal fluid |
TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Decreased after Glucocorticoid treatment. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21887273 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:75
ACCESS NO | 100640 |
GENE | SERPINA1 |
DESCRIPTION | Serpin peptidase inhibitor clade A |
NCBI ENTREZ ACCESS NO | 183 |
UNIPROT ACCESS NO | P01019 |
ORGANISM | Human |
DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
SAMPLE | Nasal fluid |
TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Enriched in acute phase response pathway. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21887273 |
DRUG TARGET | BE0001060 |
MONCLONAL ANTIBODY | N/A |
Record No:76
ACCESS NO | 100641 |
GENE | SERPING1 |
DESCRIPTION | Serpin peptidase inhibitor clade G |
NCBI ENTREZ ACCESS NO | 710 |
UNIPROT ACCESS NO | P05155 |
ORGANISM | Human |
DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
SAMPLE | Nasal fluid |
TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Enriched in acute phase response pathway. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21887273 |
DRUG TARGET | BE0002458 |
MONCLONAL ANTIBODY | N/A |
Record No:77
ACCESS NO | 100649 |
GENE | SERPIND1 |
DESCRIPTION | Heparin cofactor II |
NCBI ENTREZ ACCESS NO | 3053 |
UNIPROT ACCESS NO | P05546 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Plasma proteins |
TECHNIQUES | MALDI Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Involved in coagulation cascade. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21471098 |
DRUG TARGET | BE0000775 |
MONCLONAL ANTIBODY | Anti-Heparin Cofactor II for Human |
Record No:78
ACCESS NO | 100652 |
GENE | SERPINF2 |
DESCRIPTION | Alpha 2-Antiplasmin |
NCBI ENTREZ ACCESS NO | 5345 |
UNIPROT ACCESS NO | P08697 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Plasma proteins |
TECHNIQUES | MALDI Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Involved in coagulation cascade. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21471098 |
DRUG TARGET | BE0001125 |
MONCLONAL ANTIBODY | Anti-Alpha 2 Antiplasmin for Human |
Record No:79
ACCESS NO | 100654 |
GENE | SERPINC1 |
DESCRIPTION | Antithrombin III |
NCBI ENTREZ ACCESS NO | 462 |
UNIPROT ACCESS NO | P01008 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Plasma proteins |
TECHNIQUES | MALDI Tof |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Significantly increased in asthma patients. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21471098 |
DRUG TARGET | BE0000280 |
MONCLONAL ANTIBODY | Anti-Antithrombin IIIÂ for Mouse/Rat/Human |
Record No:80
ACCESS NO | 100681 |
GENE | Serpina3k |
DESCRIPTION | Serine protease inhibitor Clade A member 3K |
NCBI ENTREZ ACCESS NO | 20714 |
UNIPROT ACCESS NO | P07759 |
ORGANISM | BALB/c Mouse |
DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
SAMPLE | Lung tissue |
TECHNIQUES | MALDI Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Downregulated in allergen induced asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21751807 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:81
ACCESS NO | 100707 |
GENE | Scgb1a1 |
DESCRIPTION | Secretoglobin family 1A member 1 (uteroglobin) |
NCBI ENTREZ ACCESS NO | 22287 |
UNIPROT ACCESS NO | Q06318 |
ORGANISM | TSLP TG mice and BALB/c Mouse |
DISEASE PHENOTYPE | Acute and chronic asthma |
SAMPLE | Broncho Alveolar Lavage (BAL) fluid Broncho Alveol |
TECHNIQUES | LC-MS/MS and Western blot and qRT PCR |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Highly expressed in allergic lung but mRNA reduced after Dexamethasone treatment. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 22837640 |
DRUG TARGET | BE0004289 |
MONCLONAL ANTIBODY | Anti-Uteroglobin for Human |
Record No:82
ACCESS NO | 100708 |
GENE | S100A9 |
DESCRIPTION | Calgranulin B |
NCBI ENTREZ ACCESS NO | 6280 |
UNIPROT ACCESS NO | P06702 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Sputum |
TECHNIQUES | LC-MS/MS and western blot |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Less abundant in asthmatic patients. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21906793 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-S100A9 for Human |
Record No:83
ACCESS NO | 100709 |
GENE | S100A8 |
DESCRIPTION | Calgranulin A |
NCBI ENTREZ ACCESS NO | 6279 |
UNIPROT ACCESS NO | P05109 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Sputum |
TECHNIQUES | LC-MS/MS and western blot |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Less abundant in asthmatic patients. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21906793 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-MRP8 for Mouse/Human |
Record No:84
ACCESS NO | 100712 |
GENE | SERPINA1 |
DESCRIPTION | Serpin peptidase inhibitor |
NCBI ENTREZ ACCESS NO | 5265 |
UNIPROT ACCESS NO | P01009 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Sputum |
TECHNIQUES | LC-MS/MS and western blot |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Involved in airway inflammation and remodelling.Increased in induced sputum of asthamtic patients. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21906793 |
DRUG TARGET | BE0000952 |
MONCLONAL ANTIBODY | Anti-alpha 1 Antitrypsin for Human |
Record No:85
ACCESS NO | 100713 |
GENE | SMR3B |
DESCRIPTION | Submaxillary gland androgen regulated protein 3B |
NCBI ENTREZ ACCESS NO | 10879 |
UNIPROT ACCESS NO | P02814 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Sputum |
TECHNIQUES | LC-MS/MS and western blot |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Downregulated in asthma patients. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21906793 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:86
ACCESS NO | 100714 |
GENE | SCGB1A1 |
DESCRIPTION | Secretoglobin |
NCBI ENTREZ ACCESS NO | 7356 |
UNIPROT ACCESS NO | P11684 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Sputum |
TECHNIQUES | LC-MS/MS and western blot |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Downregulated leading to activation of phospholipase A2 pathway causing bronchial hyperresponsiveness. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21906793 |
DRUG TARGET | BE0004289 |
MONCLONAL ANTIBODY | Anti-Uteroglobin for Human |
Record No:87
ACCESS NO | 100763 |
GENE | Skat2 |
DESCRIPTION | Zinc finger protein SKAT2 |
NCBI ENTREZ ACCESS NO | 170740 |
UNIPROT ACCESS NO | Q9EQB9 |
ORGANISM | balb C mice |
DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
SAMPLE | Periferal blood monocytes |
TECHNIQUES | Microarray (agilent) |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Downregulated after allergen challenge.Selected based on fold change. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20840155 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:88
ACCESS NO | 100771 |
GENE | Stx3a |
DESCRIPTION | Syntaxin 3 |
NCBI ENTREZ ACCESS NO | 20908 |
UNIPROT ACCESS NO | Q8R1B7 |
ORGANISM | balb C mice |
DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
SAMPLE | Periferal blood monocytes |
TECHNIQUES | Microarray (agilent) |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Downregulated after allergen challenge.Selected based on fold change. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20840155 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Syntaxin for Rat/Human |
Record No:89
ACCESS NO | 100773 |
GENE | S100a9 |
DESCRIPTION | S100 calcium binding protein A12 |
NCBI ENTREZ ACCESS NO | 20202 |
UNIPROT ACCESS NO | P31725 |
ORGANISM | C57BL/6J mice hemizygous for human S100A12 |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Vascular smooth Muscle cells and Lung tissue |
TECHNIQUES | RT PCR ELISA Histological analysis |
OMICS | Genomics |
STUDY | Low Throughput |
COMMENTS | Calcium binding protein upregulated in serum and sputum of allergic patients. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21418345 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-S100A9 for Mouse/Rat/Human |
Record No:90
ACCESS NO | 100816 |
GENE | Scin |
DESCRIPTION | Adseverin |
NCBI ENTREZ ACCESS NO | 20259 |
UNIPROT ACCESS NO | Q60604 |
ORGANISM | BALB/c Mouse |
DISEASE PHENOTYPE | Acute and chronic asthma |
SAMPLE | Lung Tissue |
TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Involved in mucous production and upregulated during allergen exposure. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19028979 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:91
ACCESS NO | 100817 |
GENE | Serpina3g |
DESCRIPTION | Serine protease inhibitor A3G |
NCBI ENTREZ ACCESS NO | 20715 |
UNIPROT ACCESS NO | Q5I2A0 |
ORGANISM | BALB/c Mouse |
DISEASE PHENOTYPE | Acute and chronic asthma |
SAMPLE | Lung Tissue |
TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Serine and cysteine protease inhibitor. Protect cells from apoptosis. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19028979 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Spi2A for Mouse |
Record No:92
ACCESS NO | 100818 |
GENE | Serpina3n |
DESCRIPTION | Serine protease inhibitor A3N |
NCBI ENTREZ ACCESS NO | 20716 |
UNIPROT ACCESS NO | G3X8T9 |
ORGANISM | BALB/c Mouse |
DISEASE PHENOTYPE | Acute and chronic asthma |
SAMPLE | Lung Tissue |
TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19028979 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:93
ACCESS NO | 100827 |
GENE | Saa3 |
DESCRIPTION | Serum amyloid A3 protein |
NCBI ENTREZ ACCESS NO | 20210 |
UNIPROT ACCESS NO | P04918 |
ORGANISM | BALB/c Mouse |
DISEASE PHENOTYPE | Acute and chronic asthma |
SAMPLE | Lung Tissue |
TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | An acute phase reactant. Upregulated after allergen exposure in mice. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19028979 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:94
ACCESS NO | 100828 |
GENE | Slamf9 |
DESCRIPTION | Slam family member 9 |
NCBI ENTREZ ACCESS NO | 98365 |
UNIPROT ACCESS NO | Q9D780 |
ORGANISM | BALB/c Mouse |
DISEASE PHENOTYPE | Acute and chronic asthma |
SAMPLE | Lung Tissue |
TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Expressed in immune cells upregulated in long and short term allergen exposure to allergic patients. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19028979 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:95
ACCESS NO | 100829 |
GENE | Slc26a4 |
DESCRIPTION | Pendrin |
NCBI ENTREZ ACCESS NO | 23985 |
UNIPROT ACCESS NO | Q9R155 |
ORGANISM | BALB/c Mouse |
DISEASE PHENOTYPE | Acute and chronic asthma |
SAMPLE | Lung Tissue |
TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Highly expressed throughout allergen exposure. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19028979 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:96
ACCESS NO | 100840 |
GENE | Stxbp4 |
DESCRIPTION | Syntaxin-binding protein 4 |
NCBI ENTREZ ACCESS NO | 20913 |
UNIPROT ACCESS NO | Q9WV89 |
ORGANISM | SWR/J mouse |
DISEASE PHENOTYPE | Allergic conjunctivitis |
SAMPLE | Conjunctival Tissues |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Syntaxin binding protein 4 and expressed highly in conjuctiva of allergic mouse. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18658092 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Syntaxin-binding protein 4 for Mouse/Rat/Human |
Record No:97
ACCESS NO | 100851 |
GENE | SPP1 |
DESCRIPTION | Osteopontin |
NCBI ENTREZ ACCESS NO | 6696 |
UNIPROT ACCESS NO | P10451 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergy |
SAMPLE | CD4+ T cells |
TECHNIQUES | Affymetrix oligonucleotide microarray and RTPCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Controls apoptosis and influences Th1/Th2 balance. Polymorphisms in this gene is also associated with allergy. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18269679 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Osteopontin for Mouse/Human |
Record No:98
ACCESS NO | 100908 |
GENE | STAT4 |
DESCRIPTION | signal transducer and activator of transcription 4 |
NCBI ENTREZ ACCESS NO | 6775 |
UNIPROT ACCESS NO | Q14765 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic sensitization to pollen allergens |
SAMPLE | CD4+ T cells |
TECHNIQUES | Illumina microarray chips and Genome wide associat |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Involved in signal transduction and activation of transcription. |
GEO_PRIDE_ACCESS_NO | GSE18582 |
REFERENCE | 24116013 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-STAT4 for Human |
Record No:99
ACCESS NO | 100917 |
GENE | Scin |
DESCRIPTION | Scinderin |
NCBI ENTREZ ACCESS NO | 20259 |
UNIPROT ACCESS NO | Q60604 |
ORGANISM | BALB/C mice |
DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
SAMPLE | Mesenteric lymph node |
TECHNIQUES | cDNA microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Actin filament depolymerization regulation and is activated by calcium. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21211037 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SCIN for Human |
Record No:100
ACCESS NO | 100918 |
GENE | Stat3 |
DESCRIPTION | Signal transducer and activator of transcription 3 |
NCBI ENTREZ ACCESS NO | 20848 |
UNIPROT ACCESS NO | P42227 |
ORGANISM | BALB/C mice |
DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
SAMPLE | Mesenteric lymph node |
TECHNIQUES | cDNA microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Involved in production of IL21 mediated IgE production. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21211037 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-STAT3 for Rat/Human |
Record No:101
ACCESS NO | 100919 |
GENE | Svil |
DESCRIPTION | Supervillin |
NCBI ENTREZ ACCESS NO | 225115 |
UNIPROT ACCESS NO | Q8K4L3 |
ORGANISM | BALB/C mice |
DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
SAMPLE | Mesenteric lymph node |
TECHNIQUES | cDNA microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Regulate actin filament depolymerization. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21211037 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:102
ACCESS NO | 100921 |
GENE | Stard4 |
DESCRIPTION | StAR-related lipid transfer domain containing 4 |
NCBI ENTREZ ACCESS NO | 134429 |
UNIPROT ACCESS NO | Q96DR4 |
ORGANISM | BALB/C mice |
DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
SAMPLE | Mesenteric lymph node |
TECHNIQUES | cDNA microarray and RT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Involved in binding and directional transport of cholesterol in liver for bile acid synthesis. Downregulated in all three food allergen sensitization. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21211037 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:103
ACCESS NO | 100926 |
GENE | Syt4 |
DESCRIPTION | Synaptotagmin IV |
NCBI ENTREZ ACCESS NO | 20983 |
UNIPROT ACCESS NO | P40749 |
ORGANISM | BALB/C mice |
DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
SAMPLE | Mesenteric lymph node |
TECHNIQUES | cDNA microarray and RT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Upregulated in Ovalbumin sensitized patients. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21211037 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Synaptotagmin 4 for Mouse/Rat/Human |
Record No:104
ACCESS NO | 100947 |
GENE | Sap |
DESCRIPTION | Serum amyloid P |
NCBI ENTREZ ACCESS NO | 20219 |
UNIPROT ACCESS NO | P12246 |
ORGANISM | Female C57BL/6 mouse |
DISEASE PHENOTYPE | Allergy induced by fungal spore. |
SAMPLE | Lung tissue |
TECHNIQUES | Immunohistochemistry and RT-PCR |
OMICS | others |
STUDY | Low Throughput |
COMMENTS | An important inhibitor of macrophage differentiation.Protects against fungal spore induced allergy. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20673988 |
DRUG TARGET | BE0001213 |
MONCLONAL ANTIBODY | N/A |
Record No:105
ACCESS NO | 101028 |
GENE | SERPINA12 |
DESCRIPTION | Serpin A12 |
NCBI ENTREZ ACCESS NO | 145264 |
UNIPROT ACCESS NO | Q8IW75 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic eczema (AE) |
SAMPLE | Vernix |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This acute phase protein is strongly upregulated in atopic eczema. It is involved in inflammatory responses. Presence of this protein in vernix of the atopic eczema group indicate that the skin of these neonates might be prone to develop inflammation and may possibly have a physiological association with AE. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24205894 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:106
ACCESS NO | 101045 |
GENE | S100A7 |
DESCRIPTION | Protein S100-A7 |
NCBI ENTREZ ACCESS NO | 6278 |
UNIPROT ACCESS NO | P31151 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic eczema (AE) |
SAMPLE | Vernix |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is strongly down regulated in atopic eczema. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24205894 |
DRUG TARGET | BE0003756 |
MONCLONAL ANTIBODY | N/A |
Record No:107
ACCESS NO | 101053 |
GENE | S100A8 |
DESCRIPTION | Protein S100-A8 |
NCBI ENTREZ ACCESS NO | 6279 |
UNIPROT ACCESS NO | P05109 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic eczema (AE) |
SAMPLE | Vernix |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is strongly down regulated in atopic eczema. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24205894 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:108
ACCESS NO | 101079 |
GENE | SERPINB2 |
DESCRIPTION | Serine peptidase inhibitor clade B member 2 |
NCBI ENTREZ ACCESS NO | 5055 |
UNIPROT ACCESS NO | P05120 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Airway epithelial brushings |
TECHNIQUES | qPCR |
OMICS | Genomics |
STUDY | Low Throughput |
COMMENTS | Being a component of three-gene-mean provides a measurement of Th2 airway inflammation that is clinically relevant and that can serve as a valuable tool to evaluate non-invasive biomarkers to predict treatment responses to existing and emerging asthma |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 23866775 |
DRUG TARGET | BE0000969 |
MONCLONAL ANTIBODY | Anti-SerpinB2 for Human |
Record No:109
ACCESS NO | 101102 |
GENE | STAT6 |
DESCRIPTION | Signal transducer and activator of transcription 6 |
NCBI ENTREZ ACCESS NO | 6778 |
UNIPROT ACCESS NO | P42226 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Nasal epithelial cells |
TECHNIQUES | real-time RT-PCR |
OMICS | Genomics |
STUDY | Low Throughput |
COMMENTS | siRNA (si372) mediated silencing of STAT-6. The ability of IL-13 to up-regulate CCL26 mRNA expression |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 23402658 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-STAT6Â for Mouse/Human |
Record No:110
ACCESS NO | 101130 |
GENE | SERPINA1 |
DESCRIPTION | alpha-1 antitrypsin |
NCBI ENTREZ ACCESS NO | 5265 |
UNIPROT ACCESS NO | P01009 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Genomic DNA and serum |
TECHNIQUES | Genotyping and ELISA |
OMICS | Genomics |
STUDY | Low Throughput |
COMMENTS | The SNP Glu363Lys in this gene was identified as important genetic markers for use in better management of the disease. Significantly low level of α(1)AT in the serum of asthmatics as compared to controls was found. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 23226977 |
DRUG TARGET | BE0000952 |
MONCLONAL ANTIBODY | N/A |
Record No:111
ACCESS NO | 101171 |
GENE | STAB1 |
DESCRIPTION | Stabilin 1 |
NCBI ENTREZ ACCESS NO | 23166 |
UNIPROT ACCESS NO | Q9NY15 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
TECHNIQUES | Label free nano-LC-MS/MS and western blot |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It was detected in PBMCs from patients in active immunotherapy group but not in placebo group. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 22464673 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:112
ACCESS NO | 101206 |
GENE | SSRP1 |
DESCRIPTION | FACT complex subunit SSRP1 |
NCBI ENTREZ ACCESS NO | 6749 |
UNIPROT ACCESS NO | Q08945 |
ORGANISM | Human |
DISEASE PHENOTYPE | Food allergy |
SAMPLE | Peripheral blood mononuclear cells |
TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 22091390 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SSRP1 for Human |
Record No:113
ACCESS NO | 101257 |
GENE | Sele |
DESCRIPTION | E-selectin |
NCBI ENTREZ ACCESS NO | 20339 |
UNIPROT ACCESS NO | Q00690 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
SAMPLE | Lung tissue |
TECHNIQUES | real time PCR |
OMICS | Genomics |
STUDY | Low Throughput |
COMMENTS | Pretreatment with artesunate (30 mg/kg) demonstrated strong suppression of this gene that is pivotal for pulmonary recruitment of inflammatory cells like eosinophils and lymphoctyes. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21695271 |
DRUG TARGET | BE0001074 |
MONCLONAL ANTIBODY | N/A |
Record No:114
ACCESS NO | 101271 |
GENE | S100A9 |
DESCRIPTION | Calgranulin B |
NCBI ENTREZ ACCESS NO | 6280 |
UNIPROT ACCESS NO | P06702 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Exhaled Breath condensate |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Present in exhaled blood condensate of asthma patients. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 21105917 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:115
ACCESS NO | 101293 |
GENE | sICAM |
DESCRIPTION | Soluble intercellular adhesion molecule |
NCBI ENTREZ ACCESS NO | 3383 |
UNIPROT ACCESS NO | P05362 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma in children |
SAMPLE | Exhaled Breath condensate |
TECHNIQUES | Multiplex immunoassay technology |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Signifcant high expression in children with asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20205697 |
DRUG TARGET | BE0001085 |
MONCLONAL ANTIBODY | N/A |
Record No:116
ACCESS NO | 101294 |
GENE | sVCAM |
DESCRIPTION | Soluble vascular adhesion molecule |
NCBI ENTREZ ACCESS NO | 7412 |
UNIPROT ACCESS NO | P19320 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma in children |
SAMPLE | Exhaled Breath condensate |
TECHNIQUES | Multiplex immunoassay technology |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Signifcant high expression in children with asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20205697 |
DRUG TARGET | BE0001114 |
MONCLONAL ANTIBODY | N/A |
Record No:117
ACCESS NO | 101330 |
GENE | SLPI |
DESCRIPTION | Secretory leukocyte peptidase inhibitor |
NCBI ENTREZ ACCESS NO | 6590 |
UNIPROT ACCESS NO | P03973 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic airway disease |
SAMPLE | Nasal Lavage |
TECHNIQUES | Western blot |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Protects tissues against environmental irritants through its anti-inflammatory properties. Cleaved SLPI is increased in asthma which is an indicative of chymase activity. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19400896 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SLPI for Human |
Record No:118
ACCESS NO | 101362 |
GENE | Sftpd |
DESCRIPTION | Surfactant protein D |
NCBI ENTREZ ACCESS NO | 20390 |
UNIPROT ACCESS NO | P50404 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Chronic Asthma |
SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Upregulated in asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18594147 |
DRUG TARGET | BE0001107 |
MONCLONAL ANTIBODY | Anti-Surfactant protein D for Mouse/Rat/Human |
Record No:119
ACCESS NO | 101366 |
GENE | Serpinb6a |
DESCRIPTION | Serpinb6a protein |
NCBI ENTREZ ACCESS NO | 20719 |
UNIPROT ACCESS NO | F8WIV2 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Chronic Asthma |
SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Involved in cellular metabolism and expressed in chronic asthma mouse model. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18594147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:120
ACCESS NO | 101371 |
GENE | Sod1 |
DESCRIPTION | Superoxide dismutase 1 |
NCBI ENTREZ ACCESS NO | 20655 |
UNIPROT ACCESS NO | P08228 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Chronic Asthma |
SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Plays a critical role in protecting lungs from oxidative damage.Downregulated in chronic asthma mouse model. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18594147 |
DRUG TARGET | BE0002390 |
MONCLONAL ANTIBODY | Anti-Superoxide Dismutase 1 for Rat/Human |
Record No:121
ACCESS NO | 101380 |
GENE | S100a8 |
DESCRIPTION | S100 calcium-binding protein A8 |
NCBI ENTREZ ACCESS NO | 20201 |
UNIPROT ACCESS NO | P27005 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Chronic Asthma |
SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Involved in leukocyte differentiation inflammation and wound healing. Downregulated in chronic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18594147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-MRP8 for Mouse/Human |
Record No:122
ACCESS NO | 101381 |
GENE | S100a9 |
DESCRIPTION | S100 calcium-binding protein A9 |
NCBI ENTREZ ACCESS NO | 6280 |
UNIPROT ACCESS NO | P06702 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Chronic Asthma |
SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Involved in leukocyte differentiation inflammation and wound healing. Downregulated in chronic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18594147 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-S100A9 for Human |
Record No:123
ACCESS NO | 101382 |
GENE | S100a11 |
DESCRIPTION | S100 calcium-binding protein A11 |
NCBI ENTREZ ACCESS NO | 20195 |
UNIPROT ACCESS NO | P50543 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Chronic Asthma |
SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
TECHNIQUES | MALDI Tof/Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Reduced expression in chronically asthmatic mouse. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 18594147 |
DRUG TARGET | BE0002789 |
MONCLONAL ANTIBODY | Anti-S100A11 for Mouse/Rat/Human |
Record No:124
ACCESS NO | 101399 |
GENE | Saa1 |
DESCRIPTION | Serum amyloid A 1 |
NCBI ENTREZ ACCESS NO | 20208 |
UNIPROT ACCESS NO | P05366 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray and RT PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Frequently used as marker of non specific inflammation. Markedly increased in 5 time points after allergen induction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | BE0004795 |
MONCLONAL ANTIBODY | Anti-Serum Amyloid A for Human |
Record No:125
ACCESS NO | 101422 |
GENE | Selp |
DESCRIPTION | Selectin platelet |
NCBI ENTREZ ACCESS NO | 20344 |
UNIPROT ACCESS NO | Q01102 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | BE0001159 |
MONCLONAL ANTIBODY | Anti-CD62P for Mouse/Rat/Human |
Record No:126
ACCESS NO | 101428 |
GENE | Socs3 |
DESCRIPTION | Suppressor of cytokine signaling 3 |
NCBI ENTREZ ACCESS NO | 12702 |
UNIPROT ACCESS NO | O35718 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray and RT PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Transiently increased in expression in allergen induced asthmatics. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SOCS3 for Rat/Human |
Record No:127
ACCESS NO | 101437 |
GENE | Serpinb2 |
DESCRIPTION | Serine (or cysteine) peptidase inhibitor clade B member 2 |
NCBI ENTREZ ACCESS NO | 18788 |
UNIPROT ACCESS NO | P12388 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | BE0000969 |
MONCLONAL ANTIBODY | Anti-SerpinB2 for Human |
Record No:128
ACCESS NO | 101445 |
GENE | Serpine1 |
DESCRIPTION | Serine (or cysteine) peptidase inhibitor clade E member 1 |
NCBI ENTREZ ACCESS NO | 18787 |
UNIPROT ACCESS NO | G5E899 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated after 3hours and 12 hours of fungal allergen induction in asthmatic mice. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | BE0000240 |
MONCLONAL ANTIBODY | N/A |
Record No:129
ACCESS NO | 101453 |
GENE | Sema4d |
DESCRIPTION | Semaphorin 4D |
NCBI ENTREZ ACCESS NO | 20354 |
UNIPROT ACCESS NO | O09126 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Slightly upregulated after allergen induction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Semaphorin 4D for Human |
Record No:130
ACCESS NO | 101454 |
GENE | Steap4 |
DESCRIPTION | STEAP family member 4 |
NCBI ENTREZ ACCESS NO | 117167 |
UNIPROT ACCESS NO | Q923B6 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatic mice. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:131
ACCESS NO | 101476 |
GENE | Socs1 |
DESCRIPTION | Suppressor of cytokine signaling 1 |
NCBI ENTREZ ACCESS NO | 12703 |
UNIPROT ACCESS NO | O35716 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated after 3 and 12 hours of fungal allergen challenge in asthmatic mice. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:132
ACCESS NO | 101478 |
GENE | Slc39a14 |
DESCRIPTION | Solute carrier family 39 (zinc transporter) member 14 |
NCBI ENTREZ ACCESS NO | 213053 |
UNIPROT ACCESS NO | Q75N73 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated after 3 and 12 hours of fungal allergen challenge in asthmatic mice. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:133
ACCESS NO | 101482 |
GENE | S100a9 |
DESCRIPTION | S100 calcium binding protein A9 |
NCBI ENTREZ ACCESS NO | 20202 |
UNIPROT ACCESS NO | P31725 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated after 3 and 12 hours of fungal allergen challenge in asthmatic mice. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-S100A9 for Human |
Record No:134
ACCESS NO | 101497 |
GENE | Syk |
DESCRIPTION | Spleen tyrosine kinase |
NCBI ENTREZ ACCESS NO | 20963 |
UNIPROT ACCESS NO | P48025 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | BE0001316 |
MONCLONAL ANTIBODY | Anti-Syk for Mouse/Human/Rat |
Record No:135
ACCESS NO | 101504 |
GENE | Sord |
DESCRIPTION | Sorbitol dehydrogenase |
NCBI ENTREZ ACCESS NO | 20322 |
UNIPROT ACCESS NO | Q64442 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | BE0000299 |
MONCLONAL ANTIBODY | Anti-Sorbitol Dehydrogenase for Mouse/Rat/Human |
Record No:136
ACCESS NO | 101510 |
GENE | S100a8 |
DESCRIPTION | S100 calcium binding protein A8 |
NCBI ENTREZ ACCESS NO | 20201 |
UNIPROT ACCESS NO | P27005 |
ORGANISM | Female BALB/c mice |
DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
SAMPLE | Lung Tissue |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 20045013 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-MRP8 for Mouse/Human |
Record No:137
ACCESS NO | 101533 |
GENE | STAT1 |
DESCRIPTION | Signal transducer and activator of transcription 1 |
NCBI ENTREZ ACCESS NO | 6772 |
UNIPROT ACCESS NO | P42224 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic Asthma |
SAMPLE | CD4+ and CD161+ T cells |
TECHNIQUES | FACS |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Phospho-STAT1 was increased in asthmatic subjects. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919711 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-STAT1 for Mouse/Rat/Humam |
Record No:138
ACCESS NO | 101534 |
GENE | STAT6 |
DESCRIPTION | Signal transducer and activator of transcription 6 |
NCBI ENTREZ ACCESS NO | 6778 |
UNIPROT ACCESS NO | P42226 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic Asthma |
SAMPLE | CD4+ and CD161+ T cells |
TECHNIQUES | FACS |
OMICS | Others |
STUDY | Low Throughput |
COMMENTS | Phospho-STAT6 was increased in asthmatic subjects. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17919711 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-STAT6 for mouse/Human |
Record No:139
ACCESS NO | 101561 |
GENE | SCYA6 |
DESCRIPTION | Chemokine (C-C motif) ligand 6 |
NCBI ENTREZ ACCESS NO | 20305 |
UNIPROT ACCESS NO | P27784 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Involved in secreted signal transduction.Expressed after OVA induction but not hampered by IL13 inhibitor. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-CCL6 for Mouse |
Record No:140
ACCESS NO | 101570 |
GENE | SerpinA3N |
DESCRIPTION | Serine (or cysteine) peptidase inhibitor clade A member 3N |
NCBI ENTREZ ACCESS NO | 20716 |
UNIPROT ACCESS NO | G3X8T9 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | A protease inhibitor expressed in both Il13 induction and OVA challenge. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:141
ACCESS NO | 101575 |
GENE | Slc4A2 |
DESCRIPTION | Solute carrier family 4 |
NCBI ENTREZ ACCESS NO | 20535 |
UNIPROT ACCESS NO | P13808 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Involved in ion flux and expressed after IL 13 treatment. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:142
ACCESS NO | 101588 |
GENE | Ssr4 |
DESCRIPTION | Signal sequence receptor delta |
NCBI ENTREZ ACCESS NO | 20832 |
UNIPROT ACCESS NO | Q62186 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Present in the endoplasmic reticulum and expressed after IL13induction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:143
ACCESS NO | 101589 |
GENE | Sec61B |
DESCRIPTION | Sec61 beta subunit |
NCBI ENTREZ ACCESS NO | 66212 |
UNIPROT ACCESS NO | Q9CQS8 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Present in the endoplasmic reticulum and expressed after IL13induction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:144
ACCESS NO | 101597 |
GENE | Sdf5 |
DESCRIPTION | Secreted frizzled-related protein 2 |
NCBI ENTREZ ACCESS NO | 20319 |
UNIPROT ACCESS NO | P97299 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Involved in secreted signal transduction and expressed after IL 13 induction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SFRP2 for Mouse/Rat/Human |
Record No:145
ACCESS NO | 101599 |
GENE | Sprr2a |
DESCRIPTION | Small proline-rich protein 2A1 |
NCBI ENTREZ ACCESS NO | 20755 |
UNIPROT ACCESS NO | Q4KL71 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Cytoskeletal protein expressed after IL 13 induction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:146
ACCESS NO | 101614 |
GENE | Srm |
DESCRIPTION | Spermidine synthase |
NCBI ENTREZ ACCESS NO | 20810 |
UNIPROT ACCESS NO | Q64674 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Involved in metabolism and expressed after IL 13 induction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | BE0000300 |
MONCLONAL ANTIBODY | N/A |
Record No:147
ACCESS NO | 101626 |
GENE | Siat7b |
DESCRIPTION | ST6 (alpha-N-acetyl-neuraminyl-2-3-beta-galactosyl-1-3)-N-acetylgalactosaminide alpha-2-6-sialyltran |
NCBI ENTREZ ACCESS NO | 20446 |
UNIPROT ACCESS NO | P70277 |
ORGANISM | Balb/C wild-type mice |
DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
SAMPLE | Lung tissue |
TECHNIQUES | Gene Chip microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Expressed after IL 13 induction. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16402082 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:148
ACCESS NO | 101631 |
GENE | Saa2 |
DESCRIPTION | Serum amyloid A2 |
NCBI ENTREZ ACCESS NO | 20209 |
UNIPROT ACCESS NO | P05367 |
ORGANISM | Female Balb/c Mice |
DISEASE PHENOTYPE | Food allergy caused by Ovomucoid |
SAMPLE | Plasma |
TECHNIQUES | MALDI Tof Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | Overexpressed in Ovomucoid sensitized mouse. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 17897766 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Serum Amyloid A for Human |
Record No:149
ACCESS NO | 101641 |
GENE | SRp20(SRSF3) |
DESCRIPTION | Serine-arginine (SR) splicing factor |
NCBI ENTREZ ACCESS NO | 6428 |
UNIPROT ACCESS NO | P84103 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Fibroblasts from Broncho Alveolar Lavage (BAL) Flu |
TECHNIQUES | MALDI Tof Tof |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | 1.4 fold increase was observed in patients suffering from mild asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 16430780 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SFRS3 for Human |
Record No:150
ACCESS NO | 101643 |
GENE | SPP1 |
DESCRIPTION | Osteopontin |
NCBI ENTREZ ACCESS NO | 6696 |
UNIPROT ACCESS NO | P10451 |
ORGANISM | Human |
DISEASE PHENOTYPE | Insect allergy(Bee venom immunotherapy) |
SAMPLE | Peripheral Blood Mononuclear cells |
TECHNIQUES | Gene chip microarray and RT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Upregulated after venom immunotherapy. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15867867 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Osteopontin for Mouse/Human |
Record No:151
ACCESS NO | 101685 |
GENE | SERPINB3 (SCCA-1) |
DESCRIPTION | Squamous cell carcinoma antigen-1 |
NCBI ENTREZ ACCESS NO | 6317 |
UNIPROT ACCESS NO | P29508 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Bronchial epithelial cells |
TECHNIQUES | Immunoblot |
OMICS | Proteomics |
STUDY | Low Throughput |
COMMENTS | Allergen sensitization and Th2 cytokine treatment causes upregulation of this gene. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15677460 |
DRUG TARGET | BE0004463 |
MONCLONAL ANTIBODY | Anti-SerpinB3 for Human |
Record No:152
ACCESS NO | 101686 |
GENE | Serpinb3a (SCCA-1) |
DESCRIPTION | Squamous cell carcinoma antigen-1 |
NCBI ENTREZ ACCESS NO | 20248 |
UNIPROT ACCESS NO | Q8BG86 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Lung tissue |
TECHNIQUES | Real time q-PCR and Immunoassay (Immunoblot and Im |
OMICS | Genomics and Pr |
STUDY | Low Throughput |
COMMENTS | Allergen sensitization and Th2 cytokine treatment causes upregulation of this gene. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15677460 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SerpinB3 for Human |
Record No:153
ACCESS NO | 101687 |
GENE | STAT1 (STAT-1) |
DESCRIPTION | Signal transducer and activator of transcription 1 |
NCBI ENTREZ ACCESS NO | 6772 |
UNIPROT ACCESS NO | P42224 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Bronchial epithelial cells |
TECHNIQUES | Immunoblot |
OMICS | Proteomics |
STUDY | Low Throughput |
COMMENTS | IL-4 and IL-13 treatment causes phosphorylation of STAT-1 at tyrosine residue to induce SCCA gene expression in bronchial epithelial cell. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15677460 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-STAT1 (phospho Y701) [M135] for Mouse/Human |
Record No:154
ACCESS NO | 101688 |
GENE | STAT6 (STAT-6) |
DESCRIPTION | Signal transducer and activator of transcription 6 (IL-4 inducible) |
NCBI ENTREZ ACCESS NO | 6778 |
UNIPROT ACCESS NO | P42226 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Bronchial epithelial cells |
TECHNIQUES | Immunoblot |
OMICS | Proteomics |
STUDY | Low Throughput |
COMMENTS | IL-4 and IL-13 treatment causes phosphorylation of STAT-1 at tyrosine residue to induce SCCA gene expression in bronchial epithelial cell. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15677460 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-STAT6 [YE361] for Mouse/human |
Record No:155
ACCESS NO | 101689 |
GENE | Scgb1a1 (Ug) |
DESCRIPTION | Uteroglobin |
NCBI ENTREZ ACCESS NO | 22287 |
UNIPROT ACCESS NO | Q06318 |
ORGANISM | Mouse |
DISEASE PHENOTYPE | Asthma |
SAMPLE | Lung tissue |
TECHNIQUES | Real time q-PCR and Immunoassay (Immunoblot and Im |
OMICS | Genomics and Pr |
STUDY | Low Throughput |
COMMENTS | In uteroglobin knock out mouse Th2 cytokine inducible proinflammatory genes (SCCA-1 and 2) are highly upregulated. But treatment with recombinant Ug results in decrease in asthmatic symptom. Thus Uteroglobin plays a role of potent anti-inflammatory and immunomodulatory protein. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15677460 |
DRUG TARGET | BE0004289 |
MONCLONAL ANTIBODY | Anti-Uteroglobin [3A8B8] for Human |
Record No:156
ACCESS NO | 101710 |
GENE | S100A12 |
DESCRIPTION | Calgranulin C (neutrophil S100 protein) |
NCBI ENTREZ ACCESS NO | 6283 |
UNIPROT ACCESS NO | P80511 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This neutrophilic granule protein is upregulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0001206 |
MONCLONAL ANTIBODY | Anti-S100A12 [1D1] for Human |
Record No:157
ACCESS NO | 101720 |
GENE | SERPINA3 |
DESCRIPTION | Alpha 1-Antichymotrypsin (ACT) |
NCBI ENTREZ ACCESS NO | 12 |
UNIPROT ACCESS NO | P01011 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protease inhibitor is upregulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-alpha 1 Antichymotrypsin [801] for Human |
Record No:158
ACCESS NO | 101721 |
GENE | SERPINA4 |
DESCRIPTION | Serine (or cysteine) proteinase inhibitor |
NCBI ENTREZ ACCESS NO | 5267 |
UNIPROT ACCESS NO | P29622 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protease inhibitor is upregulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Kallistatin [EPR15310] for human/Mouse |
Record No:159
ACCESS NO | 101722 |
GENE | SERPINF1 |
DESCRIPTION | Serine (or cysteine) proteinase inhibitor |
NCBI ENTREZ ACCESS NO | 5176 |
UNIPROT ACCESS NO | P36955 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protease inhibitor is upregulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-PEDF [1C4] for Human |
Record No:160
ACCESS NO | 101760 |
GENE | SFTPB |
DESCRIPTION | Surfactant pulmonary associated protein B |
NCBI ENTREZ ACCESS NO | 6439 |
UNIPROT ACCESS NO | P07988 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This local matrix protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Surfactant Protein B (Mature) [SPB02 (same as 1B9)] for Mouse/Human |
Record No:161
ACCESS NO | 101769 |
GENE | S100A8 |
DESCRIPTION | Calgranulin A (S100 calcium-binding protein A8) |
NCBI ENTREZ ACCESS NO | 6279 |
UNIPROT ACCESS NO | P05109 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This acute phase protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:162
ACCESS NO | 101771 |
GENE | SAA4 |
DESCRIPTION | Serum amyloid A-4 protein (C-SAA) |
NCBI ENTREZ ACCESS NO | 6291 |
UNIPROT ACCESS NO | P35542 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This acute phase protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SAA4 [EPR2926] for Human |
Record No:163
ACCESS NO | 101773 |
GENE | S100A4 |
DESCRIPTION | Calvasculin (S100 calcium-binding protein A4) |
NCBI ENTREZ ACCESS NO | 6275 |
UNIPROT ACCESS NO | P26447 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This acute phase protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0004350 |
MONCLONAL ANTIBODY | Anti-S100A4 [EPR2761(2)] for Human |
Record No:164
ACCESS NO | 101797 |
GENE | SERPINA7 |
DESCRIPTION | Thyroxine-binding globulin |
NCBI ENTREZ ACCESS NO | 6906 |
UNIPROT ACCESS NO | SERPINA7 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This serum protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0000537 |
MONCLONAL ANTIBODY | N/A |
Record No:165
ACCESS NO | 101812 |
GENE | SHBG |
DESCRIPTION | Sex hormone-binding protein |
NCBI ENTREZ ACCESS NO | 6462 |
UNIPROT ACCESS NO | P04278 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | BE0000685 |
MONCLONAL ANTIBODY | Anti-Sex Hormone Binding Globulin [EPR6628] for Human |
Record No:166
ACCESS NO | 101822 |
GENE | SEPP1 |
DESCRIPTION | Selenoprotein P |
NCBI ENTREZ ACCESS NO | 6414 |
UNIPROT ACCESS NO | P49908 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:167
ACCESS NO | 101825 |
GENE | SUB1 |
DESCRIPTION | Activated RNA polymerase II transcription cofactor 4 |
NCBI ENTREZ ACCESS NO | 10923 |
UNIPROT ACCESS NO | P53999 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is up regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:168
ACCESS NO | 101826 |
GENE | SUSD2 |
DESCRIPTION | Sushi domain (SCR repeat)-containing |
NCBI ENTREZ ACCESS NO | 56241 |
UNIPROT ACCESS NO | Q9UGT4 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is down regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SUSD2 for Human |
Record No:169
ACCESS NO | 101828 |
GENE | SPINT1 |
DESCRIPTION | Hepatocyte growth factor activator inhibitor 1 |
NCBI ENTREZ ACCESS NO | 6692 |
UNIPROT ACCESS NO | O43278 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is down regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:170
ACCESS NO | 101836 |
GENE | SLC34A2 |
DESCRIPTION | Sodium-dependent phosphate transporter isoform-3b |
NCBI ENTREZ ACCESS NO | 10568 |
UNIPROT ACCESS NO | O95436 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma induced by allergen challenge |
SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is down regulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15951573 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:171
ACCESS NO | 101843 |
GENE | SERPINA1 |
DESCRIPTION | a1-Antitrypsin/SERPINA1 |
NCBI ENTREZ ACCESS NO | 5265 |
UNIPROT ACCESS NO | P01009 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis |
SAMPLE | Nasal mucus |
TECHNIQUES | LC-MS/MS and western blot |
OMICS | Proteomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | It showed 2.5 fold upregulation in rhinitis patients. Its primary target is elastase but it also moderately inhibits plasmin and thrombin with irreversible inhibition of trypsin and plasminogen activator. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24290289 |
DRUG TARGET | BE0000952 |
MONCLONAL ANTIBODY | N/A |
Record No:172
ACCESS NO | 101847 |
GENE | SLPI |
DESCRIPTION | Antileukoproteinase |
NCBI ENTREZ ACCESS NO | 6590 |
UNIPROT ACCESS NO | P03973 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis |
SAMPLE | Nasal mucus |
TECHNIQUES | LC-MS/MS |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | It showed 0.6 fold expression change in rhinitis patients. It is a secreted acid-stable protease inhibitor with strong affinities for trypsin and elastase and cathepsin G. It protects the epithelium and prevent damage to mucosal tissues through protease inhibition such as elastases that cannot degrade laminin. It regulates epithelial proliferation through MAPK pathway inhibition and have immunomodulatory effects in the mucosa. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 24290289 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:173
ACCESS NO | 101851 |
GENE | SCGB1A1 |
DESCRIPTION | Uteroglobin |
NCBI ENTREZ ACCESS NO | 7356 |
UNIPROT ACCESS NO | P11684 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic Rhinitis induced by pollen allergen |
SAMPLE | Nasal lavage fluids |
TECHNIQUES | Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This anti inflammatory gene showed lower expression levels in patients than in controls. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15836756 |
DRUG TARGET | BE0004289 |
MONCLONAL ANTIBODY | Anti-Uteroglobin [3A8B8]Â for Human |
Record No:174
ACCESS NO | 101852 |
GENE | SCGB2A1 |
DESCRIPTION | Mammaglobin 2 |
NCBI ENTREZ ACCESS NO | 4246 |
UNIPROT ACCESS NO | O75556 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic Rhinitis induced by pollen allergen |
SAMPLE | Nasal lavage fluids |
TECHNIQUES | Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This anti inflammatory gene showed lower expression levels in patients than in controls. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15836756 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:175
ACCESS NO | 101853 |
GENE | SMAD5 |
DESCRIPTION | SMAD family member 5 |
NCBI ENTREZ ACCESS NO | 4090 |
UNIPROT ACCESS NO | Q99717 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic Rhinitis induced by pollen allergen |
SAMPLE | Nasal lavage fluids |
TECHNIQUES | Affymetrix microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | This anti inflammatory gene showed lower expression levels in patients than in controls. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15836756 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:176
ACCESS NO | 101865 |
GENE | SERPINA1 |
DESCRIPTION | Serpin peptidase inhibitor clade A member 1 |
NCBI ENTREZ ACCESS NO | 5265 |
UNIPROT ACCESS NO | P01009 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Plasma |
TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is up regulated in atopic dermatitis patient. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19116453 |
DRUG TARGET | BE0000952 |
MONCLONAL ANTIBODY | N/A |
Record No:177
ACCESS NO | 101894 |
GENE | SYNE2 |
DESCRIPTION | Synaptic nuclei expressed gene 2 |
NCBI ENTREZ ACCESS NO | 23224 |
UNIPROT ACCESS NO | Q8WXH0 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Fibroblast |
TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is down regulated in atopic fibroblasts comparative to normal fibroblasts. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15468290 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Nesprin 2 for Human |
Record No:178
ACCESS NO | 101909 |
GENE | SYT9 |
DESCRIPTION | Synaptotagmin IX |
NCBI ENTREZ ACCESS NO | 143425 |
UNIPROT ACCESS NO | Q86SS6 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Peripheral blood eosinophils |
TECHNIQUES | 2DE-PAGE and MALDI-TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15832365 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SYT9 for Mouse/Rat/Human |
Record No:179
ACCESS NO | 101923 |
GENE | STAC |
DESCRIPTION | Stac protein |
NCBI ENTREZ ACCESS NO | 6769 |
UNIPROT ACCESS NO | Q99469 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Peripheral blood eosinophils |
TECHNIQUES | 2DE-PAGE and MALDI-TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15832365 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-STAC for Mouse/Rat/Human |
Record No:180
ACCESS NO | 101935 |
GENE | STAT1 |
DESCRIPTION | Signal transducer and activator of transcription 1-alpha/beta |
NCBI ENTREZ ACCESS NO | 6772 |
UNIPROT ACCESS NO | P42224 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic dermatitis |
SAMPLE | Peripheral blood eosinophils |
TECHNIQUES | 2DE-PAGE and MALDI-TOF |
OMICS | Proteomics |
STUDY | High Throughput |
COMMENTS | This protein is upregulated in healthy donors eosinophils. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 15832365 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-STAT1 (phospho Y701) for Mouse/Human |
Record No:181
ACCESS NO | 101939 |
GENE | SVIL |
DESCRIPTION | Supervillin |
NCBI ENTREZ ACCESS NO | 6840 |
UNIPROT ACCESS NO | O95425 |
ORGANISM | Human(Asthmatic children) |
DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
SAMPLE | Peripheral Blood Mononuclear Cells |
TECHNIQUES | Microarray and RT-PCR |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated in asthmatic children. Involved in cellular function and maintenance. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19187333 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:182
ACCESS NO | 101951 |
GENE | S100A9 |
DESCRIPTION | S100 calcium binding protein A9 |
NCBI ENTREZ ACCESS NO | 6280 |
UNIPROT ACCESS NO | P06702 |
ORGANISM | Human(Asthmatic children) |
DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
SAMPLE | Peripheral Blood Mononuclear Cells |
TECHNIQUES | Microarray and RT-PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Upregulated in asthma. Also significantly upregulated in the infected control group compared to non infected control. |
GEO_PRIDE_ACCESS_NO | N/A |
REFERENCE | 19187333 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-S100A9 for Human |
Record No:183
ACCESS NO | 101974 |
GENE | SH3KBP1 |
DESCRIPTION | SH3-domain kinase binding protein 1 |
NCBI ENTREZ ACCESS NO | 30011 |
UNIPROT ACCESS NO | Q96B97 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and allergic rhinitis |
SAMPLE | Epithelial cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Expressed in patients with allergic rhinitis with or without asthma in upper airways. |
GEO_PRIDE_ACCESS_NO | GSE51392 |
REFERENCE | 24475887 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SH3KBP1 for Human |
Record No:184
ACCESS NO | 101980 |
GENE | SLC23A2 |
DESCRIPTION | Solute carrier family 23 (ascorbic acid transporter) member 2 |
NCBI ENTREZ ACCESS NO | 9962 |
UNIPROT ACCESS NO | Q9UGH3 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and allergic rhinitis |
SAMPLE | Epithelial cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Downregulated in patients with allergic rhinitis with or without asthma in the upper airways. |
GEO_PRIDE_ACCESS_NO | GSE51392 |
REFERENCE | 24475887 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:185
ACCESS NO | 101995 |
GENE | SSR1 |
DESCRIPTION | Signal sequence receptor alpha |
NCBI ENTREZ ACCESS NO | 6745 |
UNIPROT ACCESS NO | P43307 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and allergic rhinitis |
SAMPLE | Epithelial cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Downregulated in the upper airways in patients with allergic rhinitis and asthma. |
GEO_PRIDE_ACCESS_NO | GSE51392 |
REFERENCE | 24475887 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-TRAP alpha for Mouse/Rat/Human |
Record No:186
ACCESS NO | 102005 |
GENE | SHISA2 |
DESCRIPTION | Shisa family member 2 |
NCBI ENTREZ ACCESS NO | 387914 |
UNIPROT ACCESS NO | Q6UWI4 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and allergic rhinitis |
SAMPLE | Epithelial cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated in the lower airways in patients with allergic rhinitis. |
GEO_PRIDE_ACCESS_NO | GSE51392 |
REFERENCE | 24475887 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:187
ACCESS NO | 102006 |
GENE | S100A7A |
DESCRIPTION | S100 calcium binding protein A7A |
NCBI ENTREZ ACCESS NO | 338324 |
UNIPROT ACCESS NO | Q86SG5 |
ORGANISM | Human |
DISEASE PHENOTYPE | Asthma and allergic rhinitis |
SAMPLE | Epithelial cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated in the lower airways in patients with allergic rhinitis. |
GEO_PRIDE_ACCESS_NO | GSE51392 |
REFERENCE | 24475887 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:188
ACCESS NO | 102042 |
GENE | SERTAD4 |
DESCRIPTION | SERTA domain containing 4 |
NCBI ENTREZ ACCESS NO | 56256 |
UNIPROT ACCESS NO | Q9NUC0 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis and asthma |
SAMPLE | Bronchial epithelial cells |
TECHNIQUES | Microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
GEO_PRIDE_ACCESS_NO | GSE44037 |
REFERENCE | 24282527 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:189
ACCESS NO | 102043 |
GENE | SKAP2 |
DESCRIPTION | Src kinase associated phosphoprotein 2 |
NCBI ENTREZ ACCESS NO | 8935 |
UNIPROT ACCESS NO | O75563 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis and asthma |
SAMPLE | Bronchial epithelial cells |
TECHNIQUES | Microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
GEO_PRIDE_ACCESS_NO | GSE44037 |
REFERENCE | 24282527 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:190
ACCESS NO | 102044 |
GENE | SPDEF |
DESCRIPTION | SAM pointed domain containing ets transcription factor |
NCBI ENTREZ ACCESS NO | 25803 |
UNIPROT ACCESS NO | O95238 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis and asthma |
SAMPLE | Bronchial epithelial cells |
TECHNIQUES | Microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
GEO_PRIDE_ACCESS_NO | GSE44037 |
REFERENCE | 24282527 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SPDEF for Human |
Record No:191
ACCESS NO | 102045 |
GENE | ST6GALNAC1 |
DESCRIPTION | Acetylgalactosaminide alpha-2-6-sialyltransferase 1 |
NCBI ENTREZ ACCESS NO | 55808 |
UNIPROT ACCESS NO | Q9NSC7 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis and asthma |
SAMPLE | Bronchial epithelial cells |
TECHNIQUES | Microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
GEO_PRIDE_ACCESS_NO | GSE44037 |
REFERENCE | 24282527 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:192
ACCESS NO | 102046 |
GENE | STOM |
DESCRIPTION | Stomatin |
NCBI ENTREZ ACCESS NO | 2040 |
UNIPROT ACCESS NO | P27105 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis and asthma |
SAMPLE | Bronchial epithelial cells |
TECHNIQUES | Microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
GEO_PRIDE_ACCESS_NO | GSE44037 |
REFERENCE | 24282527 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-STOM for Mouse/Rat/Human |
Record No:193
ACCESS NO | 102060 |
GENE | SELM |
DESCRIPTION | Selenoprotein M |
NCBI ENTREZ ACCESS NO | 140606 |
UNIPROT ACCESS NO | Q8WWX9 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic rhinitis and asthma |
SAMPLE | Nasal epithelial cells |
TECHNIQUES | Microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
GEO_PRIDE_ACCESS_NO | GSE44037 |
REFERENCE | 24282527 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Selenoprotein M for Human |
Record No:194
ACCESS NO | 102072 |
GENE | STK17B |
DESCRIPTION | Serine/threonine kinase 17b |
NCBI ENTREZ ACCESS NO | 9262 |
UNIPROT ACCESS NO | O94768 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic asthma |
SAMPLE | CD4+ T cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Differentially expressed in asthma. Involved in apoptosis. |
GEO_PRIDE_ACCESS_NO | GSE14908 |
REFERENCE | 19414752 |
DRUG TARGET | BE0004328 |
MONCLONAL ANTIBODY | Anti-DRAK2 for Human |
Record No:195
ACCESS NO | 102078 |
GENE | SOCS2 |
DESCRIPTION | Suppressor of cytokine signaling 2 |
NCBI ENTREZ ACCESS NO | 8835 |
UNIPROT ACCESS NO | O14508 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic asthma |
SAMPLE | CD4+ T cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Activated in asthma. Involved in inflammation and immunoregulation. |
GEO_PRIDE_ACCESS_NO | GSE14908 |
REFERENCE | 19414752 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SOCS2 for Human |
Record No:196
ACCESS NO | 102083 |
GENE | SPINT2 |
DESCRIPTION | Serine peptidase inhibitor Kunitz type 2 |
NCBI ENTREZ ACCESS NO | 10653 |
UNIPROT ACCESS NO | O43291 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic asthma |
SAMPLE | CD4+ T cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Differentially expressed in asthma. Expressed in Th2 cells. |
GEO_PRIDE_ACCESS_NO | GSE14908 |
REFERENCE | 19414752 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-HGFA Inhibitor 2 for Mouse/Rat/Human |
Record No:197
ACCESS NO | 102098 |
GENE | SLC26A11 |
DESCRIPTION | Solute carrier family 26 member 11 |
NCBI ENTREZ ACCESS NO | 284129 |
UNIPROT ACCESS NO | Q86WA9 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic asthma |
SAMPLE | CD4+ T cells |
TECHNIQUES | Microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Activated in asthma. Involved in solute carrier activity. |
GEO_PRIDE_ACCESS_NO | GSE14908 |
REFERENCE | 19414752 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:198
ACCESS NO | 102099 |
GENE | SLC37A3 |
DESCRIPTION | Solute carrier family 37 member 3 |
NCBI ENTREZ ACCESS NO | 84255 |
UNIPROT ACCESS NO | Q8NCC5 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic asthma |
SAMPLE | CD4+ T cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Differentially expressed in asthma. Involved in solute carrier activity. |
GEO_PRIDE_ACCESS_NO | GSE14908 |
REFERENCE | 19414752 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:199
ACCESS NO | 102100 |
GENE | SLC39A8 |
DESCRIPTION | Solute carrier family 39 member 8 |
NCBI ENTREZ ACCESS NO | 64116 |
UNIPROT ACCESS NO | Q9C0K1 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic asthma |
SAMPLE | CD4+ T cells |
TECHNIQUES | Microarray and real time PCR |
OMICS | Genomics |
STUDY | High Throughput and Low Throughput |
COMMENTS | Differentially expressed in asthma. Involved in solute carrier activity. |
GEO_PRIDE_ACCESS_NO | GSE14908 |
REFERENCE | 19414752 |
DRUG TARGET | |
MONCLONAL ANTIBODY | N/A |
Record No:200
ACCESS NO | 102136 |
GENE | SNTB1 |
DESCRIPTION | Syntrophin beta 1 |
NCBI ENTREZ ACCESS NO | 6641 |
UNIPROT ACCESS NO | Q13884 |
ORGANISM | Human |
DISEASE PHENOTYPE | Atopic asthma |
SAMPLE | CD4+ T cells |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Differentially expressed in asthma. |
GEO_PRIDE_ACCESS_NO | GSE14908 |
REFERENCE | 19414752 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-Syntrophin for Mouse/Rat/Human |
Record No:201
ACCESS NO | 102146 |
GENE | SERPINB2 |
DESCRIPTION | Serpin peptidase inhibitor clade B member B2 |
NCBI ENTREZ ACCESS NO | 5055 |
UNIPROT ACCESS NO | P05120 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic asthma |
SAMPLE | Bronchial Biopsy |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated in allergic asthma. It is a proteolytic enzyme. |
GEO_PRIDE_ACCESS_NO | GSE41649 |
REFERENCE | 19842841 |
DRUG TARGET | BE0000969 |
MONCLONAL ANTIBODY | Anti-SerpinB2 for Human |
Record No:202
ACCESS NO | 102147 |
GENE | SERPINB4 |
DESCRIPTION | Serpin peptidase inhibitor clade B member B4 |
NCBI ENTREZ ACCESS NO | 6318 |
UNIPROT ACCESS NO | P48594 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic asthma |
SAMPLE | Bronchial Biopsy |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated in allergic asthma. It is a proteolytic enzyme. |
GEO_PRIDE_ACCESS_NO | GSE41649 |
REFERENCE | 19842841 |
DRUG TARGET | |
MONCLONAL ANTIBODY | Anti-SERPINB4 for Human(Predicted) |
Record No:203
ACCESS NO | 102151 |
GENE | S100P |
DESCRIPTION | S100 calcium-binding protein P |
NCBI ENTREZ ACCESS NO | 6286 |
UNIPROT ACCESS NO | P25815 |
ORGANISM | Human |
DISEASE PHENOTYPE | Allergic asthma |
SAMPLE | Bronchial Biopsy |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
COMMENTS | Upregulated in allergic asthma. |
GEO_PRIDE_ACCESS_NO | GSE41649 |
REFERENCE | 19842841 |
DRUG TARGET | BE0001191 |
MONCLONAL ANTIBODY | Anti-S100P for Human |