BROWSE RESULT OF T
| 133 Records |
| ACCESS NO | 100018 |
| GENE | TYMS |
| DESCRIPTION | Thymidylate synthetase |
| NCBI ENTREZ ACCESS NO | 7298 |
| UNIPROT ACCESS NO | P04818 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is a stress responsive protein. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | BE0000324 |
| MONCLONAL ANTIBODY | N/A |
Record No:2
| ACCESS NO | 100035 |
| GENE | TXLNGY (CYorf15B) |
| DESCRIPTION | Taxilin gamma pseudogene Y-linked |
| NCBI ENTREZ ACCESS NO | 246126 |
| UNIPROT ACCESS NO | Q9BZA5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in high SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:3
| ACCESS NO | 100041 |
| GENE | TUBB2A |
| DESCRIPTION | Tubulin beta 2A class IIa |
| NCBI ENTREZ ACCESS NO | 7280 |
| UNIPROT ACCESS NO | Q13885 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma ( comparison between high and low socio-economic conditions [SEC]) |
| SAMPLE | CD2+ cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated more in high SEC group. |
| GEO_PRIDE_ACCESS_NO | GSE7894 |
| REFERENCE | 19001005 |
| DRUG TARGET | BE0003400 |
| MONCLONAL ANTIBODY | Anti-TUBB2A for Mouse/Rat/Human |
Record No:4
| ACCESS NO | 100063 |
| GENE | TLR2 |
| DESCRIPTION | Toll-like receptor 2 |
| NCBI ENTREZ ACCESS NO | 7097 |
| UNIPROT ACCESS NO | O60603 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in innate immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TLR2 for Human/Monkey |
Record No:5
| ACCESS NO | 100064 |
| GENE | TLR4 |
| DESCRIPTION | Toll-like receptor 4 |
| NCBI ENTREZ ACCESS NO | 7099 |
| UNIPROT ACCESS NO | O00206 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in innate immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TLR4 [HTA125] for Rat/Human/Monkey |
Record No:6
| ACCESS NO | 100065 |
| GENE | TLR7 |
| DESCRIPTION | Toll-like receptor 7 |
| NCBI ENTREZ ACCESS NO | 51284 |
| UNIPROT ACCESS NO | Q9NYK1 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in innate immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TLR7 for Human |
Record No:7
| ACCESS NO | 100066 |
| GENE | TLR8 |
| DESCRIPTION | Toll-like receptor 8 |
| NCBI ENTREZ ACCESS NO | 51311 |
| UNIPROT ACCESS NO | Q9NR97 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in innate immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TLR8 for Mouse/Human |
Record No:8
| ACCESS NO | 100076 |
| GENE | THBS1 |
| DESCRIPTION | Thrombospondin 1 |
| NCBI ENTREZ ACCESS NO | 7057 |
| UNIPROT ACCESS NO | P07996 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in innate immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Thrombospondin for Mouse/Rat/Human |
Record No:9
| ACCESS NO | 100078 |
| GENE | TNFAIP6 |
| DESCRIPTION | Tumor necrosis factor alpha-induced protein 6 |
| NCBI ENTREZ ACCESS NO | 7130 |
| UNIPROT ACCESS NO | P98066 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in innate immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:10
| ACCESS NO | 100085 |
| GENE | TNFSF4 |
| DESCRIPTION | Tumor necrosis factor (ligand) superfamily member 4 |
| NCBI ENTREZ ACCESS NO | 7292 |
| UNIPROT ACCESS NO | P23510 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:11
| ACCESS NO | 100092 |
| GENE | THBD |
| DESCRIPTION | Thrombomodulin |
| NCBI ENTREZ ACCESS NO | 7056 |
| UNIPROT ACCESS NO | P07204 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Acute asthma and interaction between Innate Antiviral and Atopic immuno-inflammatory pathway |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Microarray and qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in complement and coagulation cascade. |
| GEO_PRIDE_ACCESS_NO | GSE16032 |
| REFERENCE | 19620293 |
| DRUG TARGET | BE0001151 |
| MONCLONAL ANTIBODY | Anti-Thrombomodulin for Human |
Record No:12
| ACCESS NO | 100117 |
| GENE | Tgtp1 (Tgtp) |
| DESCRIPTION | T cell–specific GTPase |
| NCBI ENTREZ ACCESS NO | 21822 |
| UNIPROT ACCESS NO | Q62293 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic asthma and the role of IL-4 and IL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This intracellular signaling protein is an asthma signature gene highly induced by Th2 cytokines such as IL-4 and IL-13. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19249085 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:13
| ACCESS NO | 100195 |
| GENE | TNFAIP3 |
| DESCRIPTION | Tumour necrosis factor alpha - induced protein 3 |
| NCBI ENTREZ ACCESS NO | 7128 |
| UNIPROT ACCESS NO | P21580 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This is an transcription factor significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TNFAIP3 for Human |
Record No:14
| ACCESS NO | 100196 |
| GENE | TNIP2 |
| DESCRIPTION | TNFAIP3 interacting protein 2 |
| NCBI ENTREZ ACCESS NO | 79155 |
| UNIPROT ACCESS NO | Q8NFZ5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is an transcription factor significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:15
| ACCESS NO | 100231 |
| GENE | TRBV5-4 |
| DESCRIPTION | T cell receptor beta variable 5-4 |
| NCBI ENTREZ ACCESS NO | 28611 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:16
| ACCESS NO | 100234 |
| GENE | TANC2 (DKFZP564D166) |
| DESCRIPTION | Tetratricopeptide repeat ankyrin repeat |
| NCBI ENTREZ ACCESS NO | 26115 |
| UNIPROT ACCESS NO | Q9HCD6 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell |
| SAMPLE | Human airway epithelial cell |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This gene is significantly up regulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919147 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:17
| ACCESS NO | 100251 |
| GENE | TNFAIP3 |
| DESCRIPTION | Tumor necrosis factor alpha-induced protein 3 |
| NCBI ENTREZ ACCESS NO | 7128 |
| UNIPROT ACCESS NO | P21580 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is an inhibitor of apoptosis. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TNFAIP3 for Human |
Record No:18
| ACCESS NO | 100263 |
| GENE | TIA1 |
| DESCRIPTION | TIA1 cytotoxic granule-associated RNA binding protein |
| NCBI ENTREZ ACCESS NO | 7072 |
| UNIPROT ACCESS NO | P31483 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma exacerbation after rhinovirus infection |
| SAMPLE | Primary bronchial epithelial cells |
| TECHNIQUES | Affymetrix GeneChip Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is an apoptotic inducer downregulated in rhinovirus infection. |
| GEO_PRIDE_ACCESS_NO | GSE13396 |
| REFERENCE | 19710636 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TIA1 [TIA-1] for Mouse/Rat/Human |
Record No:19
| ACCESS NO | 100283 |
| GENE | TIPRL |
| DESCRIPTION | TIP41 (TOR signalling pathway regulator-like) |
| NCBI ENTREZ ACCESS NO | 261726 |
| UNIPROT ACCESS NO | O75663 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is upregulated in asthma exacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:20
| ACCESS NO | 100299 |
| GENE | Tnfrsf21 |
| DESCRIPTION | Tumor necrosis factor receptor superfamily member 21 |
| NCBI ENTREZ ACCESS NO | 94185 |
| UNIPROT ACCESS NO | Q9EPU5 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Aspergillus fumigatus allergens |
| SAMPLE | Peripheral blood monocytes |
| TECHNIQUES | DNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This is a cytokine receptor involved in immune signaling. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:21
| ACCESS NO | 100320 |
| GENE | Tgfbr2 |
| DESCRIPTION | Transforming growth factor beta -receptor II |
| NCBI ENTREZ ACCESS NO | 81810 |
| UNIPROT ACCESS NO | P38438 |
| ORGANISM | Rat |
| DISEASE PHENOTYPE | Early airway response (EAR) phase of asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | Serial analysis of gene expression (SAGE) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in MAPK signalling pathway and controls adherens junction. |
| GEO_PRIDE_ACCESS_NO | GSE2475 |
| REFERENCE | 18922145 |
| DRUG TARGET | BE0001861 |
| MONCLONAL ANTIBODY | Anti-TGF beta Receptor II for Human |
Record No:22
| ACCESS NO | 100336 |
| GENE | Trf |
| DESCRIPTION | Transferrin |
| NCBI ENTREZ ACCESS NO | 22041 |
| UNIPROT ACCESS NO | Q921I1 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced chemicals |
| SAMPLE | Broncho Alveolar Lavage (BAL) |
| TECHNIQUES | 2D DIGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in iron metabolism. This protein has been found to be upregulated in the BAL fluid chemically induced asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20860378 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TRF1 for Human |
Record No:23
| ACCESS NO | 100348 |
| GENE | TYMP (ECGF1) |
| DESCRIPTION | Endothelial cell growth factor 1 |
| NCBI ENTREZ ACCESS NO | 1890 |
| UNIPROT ACCESS NO | P19971 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is upregulated in asthma exacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | BE0002193 |
| MONCLONAL ANTIBODY | Anti-Thymidine Phosphorylase for Mouse/Human |
Record No:24
| ACCESS NO | 100357 |
| GENE | TAPBP |
| DESCRIPTION | TAP binding protein |
| NCBI ENTREZ ACCESS NO | 6892 |
| UNIPROT ACCESS NO | O15533 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Illumina Human Ref8 BeadChip arrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It participates in cellular function and maintainance. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:25
| ACCESS NO | 100363 |
| GENE | Tuba1c |
| DESCRIPTION | Tubulin alpha chain isotype M-alpha-6 |
| NCBI ENTREZ ACCESS NO | 22146 |
| UNIPROT ACCESS NO | P68373 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergen induced asthma and Dexamethasone treatment |
| SAMPLE | Broncho Alveolar Lavage (BAL) |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Tubulin might contribute to the etiology of asthma by impairing ciliary motion and affecting cytoskeletal signaling. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15378748 |
| DRUG TARGET | BE0001388 |
| MONCLONAL ANTIBODY | Anti-TUBA6 for Human |
Record No:26
| ACCESS NO | 100378 |
| GENE | Txn1 |
| DESCRIPTION | Thioredoxin |
| NCBI ENTREZ ACCESS NO | 22166 |
| UNIPROT ACCESS NO | P10639 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | 2D PAGE andLC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is down regulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20029843 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:27
| ACCESS NO | 100383 |
| GENE | Tcn2 |
| DESCRIPTION | Transcobalamin-2 |
| NCBI ENTREZ ACCESS NO | 21452 |
| UNIPROT ACCESS NO | O88968 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma exacerbation and role of ambient particulate matter |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | 2D PAGE andLC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This gene is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20029843 |
| DRUG TARGET | BE0000362 |
| MONCLONAL ANTIBODY | Anti-TCN2 for Human |
Record No:28
| ACCESS NO | 100411 |
| GENE | THBS1 |
| DESCRIPTION | Thrombospondin |
| NCBI ENTREZ ACCESS NO | 102130245 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Monkey |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA microarrays and Quantitative RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is involved in tissue remodeling. It is not or minimally regulated by IL4. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 12049661 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Thrombospondin for Human/Mouse/Rat |
Record No:29
| ACCESS NO | 100412 |
| GENE | TIMP1(TIMP-1) |
| DESCRIPTION | TIMP metallopeptidase inhibitor 1 |
| NCBI ENTREZ ACCESS NO | 102144412 |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Monkey |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | DNA microarrays |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in tissue remodeling. It is significantly modulated by IL4. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 12049661 |
| DRUG TARGET | BE0003371 |
| MONCLONAL ANTIBODY | Anti-TIMP1 for Human |
Record No:30
| ACCESS NO | 100415 |
| GENE | TUBB |
| DESCRIPTION | Tubulin-beta |
| NCBI ENTREZ ACCESS NO | 203068 |
| UNIPROT ACCESS NO | P07437 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Bronchial epithelial cells stimulated with leukotr |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS followed by flow cytometr |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is known as a marker of ciliated cells in bronchial epithelium. In this study tubulin beta gene was found to be significantly down regulated. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20219718 |
| DRUG TARGET | BE0000143 |
| MONCLONAL ANTIBODY | Anti-TUBB2A for Mouse/Rat/Human |
Record No:31
| ACCESS NO | 100431 |
| GENE | TPT1 |
| DESCRIPTION | Translationally-controlled tumor protein |
| NCBI ENTREZ ACCESS NO | 7178 |
| UNIPROT ACCESS NO | P31947 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | bronchial epithelial cells stimulated with TGF bet |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It is downregulated in asthma inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20219718 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TCTP for Mouse/Rat/Human |
Record No:32
| ACCESS NO | 100477 |
| GENE | TSHZ3 |
| DESCRIPTION | Teashirt zinc finger homeobox 3 |
| NCBI ENTREZ ACCESS NO | 57616 |
| UNIPROT ACCESS NO | Q63HK5 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Airway smooth muscle cell (ASM) line |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is downregulated in ASM after dexamethasone treatment. |
| GEO_PRIDE_ACCESS_NO | GSE3946 |
| REFERENCE | 21257922 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-NOR1 for Human |
Record No:33
| ACCESS NO | 100487 |
| GENE | TGM3 |
| DESCRIPTION | Protein-glutamine gamma-glutamyltransferase E |
| NCBI ENTREZ ACCESS NO | 7053 |
| UNIPROT ACCESS NO | Q08188 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis and eczema |
| SAMPLE | Skin tapings |
| TECHNIQUES | nano-HPLC-MS/MS (ion trap) |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | It mediates the crosslinking of loricrin to small proline rich proteins; this complex further reinforces the cell membrane. It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211653 |
| DRUG TARGET | BE0001273 |
| MONCLONAL ANTIBODY | Anti-Transglutaminase 3 for Human |
Record No:34
| ACCESS NO | 100516 |
| GENE | Tgfb1 |
| DESCRIPTION | transforming growth factor beta 1 |
| NCBI ENTREZ ACCESS NO | 21803 |
| UNIPROT ACCESS NO | P04202 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and role of Galectin-4 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Microarray-affymetrix + Real time RT PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is an intermediary cytokine involved in SOCS3 expression. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21547260 |
| DRUG TARGET | BE0000984 |
| MONCLONAL ANTIBODY | Anti-TGF beta 1 for Human/Pig/sheep |
Record No:35
| ACCESS NO | 100533 |
| GENE | Tff2 |
| DESCRIPTION | Trefoil factor 2 |
| NCBI ENTREZ ACCESS NO | 21785 |
| UNIPROT ACCESS NO | Q03404 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Tissue from left lung |
| TECHNIQUES | Affymetrix gene chip cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is known to be involved in epithelial restitution and maintenance of mucosal integrity in the respiratory tract. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18087161 |
| DRUG TARGET | BE0004464 |
| MONCLONAL ANTIBODY | Anti-Spasmolytic Polypeptide for Human/mouse |
Record No:36
| ACCESS NO | 100538 |
| GENE | Timp4 |
| DESCRIPTION | Tissue inhibitor of metalloproteinase 4 |
| NCBI ENTREZ ACCESS NO | 110595 |
| UNIPROT ACCESS NO | Q9JHB3 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Tissue from left lung |
| TECHNIQUES | Affymetrix gene chip cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18087161 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TIMP4 for Human/Rabbit |
Record No:37
| ACCESS NO | 100540 |
| GENE | Tpm3 |
| DESCRIPTION | Tropomyosin 3 |
| NCBI ENTREZ ACCESS NO | 117557 |
| UNIPROT ACCESS NO | Q63610 |
| ORGANISM | Norway brown rat |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Right cranial lung lobe |
| TECHNIQUES | Affymetrix microarray + quantitative PCR(real time |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpression of this gene in asthmatic lungs result in an increase in the proliferation rate of airway smooth muscle (ASM) cells. It is a feature of remodeling that causes the thickening of airway walls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19176365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Tropomyosin for Rat/Human |
Record No:38
| ACCESS NO | 100544 |
| GENE | Tgfb3 |
| DESCRIPTION | Transforming growth factor beta 3 |
| NCBI ENTREZ ACCESS NO | 25717 |
| UNIPROT ACCESS NO | Q07258 |
| ORGANISM | Norway brown rat |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Right cranial lung lobe |
| TECHNIQUES | Affymetrix microarray + quantitative PCR(real time |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It can increase the proliferation of smooth muscle cells and the deposition of ECM protein. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19176365 |
| DRUG TARGET | BE0004506 |
| MONCLONAL ANTIBODY | Anti-TGFB3 for Human |
Record No:39
| ACCESS NO | 100557 |
| GENE | Tyrobp |
| DESCRIPTION | TYRO protein tyrosine kinase binding protein |
| NCBI ENTREZ ACCESS NO | 22177 |
| UNIPROT ACCESS NO | O54885 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Tissue from bronchial biopsy |
| TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in inflammatory signaling and found to be down regulated in this study. |
| GEO_PRIDE_ACCESS_NO | GSE15823 |
| REFERENCE | 15038835 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-DAP12 for Human |
Record No:40
| ACCESS NO | 100561 |
| GENE | Tcf21 |
| DESCRIPTION | Transcription factor 21 |
| NCBI ENTREZ ACCESS NO | 21412 |
| UNIPROT ACCESS NO | O35437 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Tissue from bronchial biopsy |
| TECHNIQUES | Microarray-Affymetrix HG-U95Av2 GeneChips |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | It is involved in immune signaling. |
| GEO_PRIDE_ACCESS_NO | GSE15823 |
| REFERENCE | 15038835 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TCF21 for Human |
Record No:41
| ACCESS NO | 100570 |
| GENE | TUBB2A |
| DESCRIPTION | tubulin beta2 |
| NCBI ENTREZ ACCESS NO | 7280 |
| UNIPROT ACCESS NO | Q13885 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | CD3+T cell |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | A subunit of microtubules which combines ciliary motion with cellular function through the cytoskeleton and involved in airway remodelling. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17550934 |
| DRUG TARGET | BE0003400 |
| MONCLONAL ANTIBODY | Anti-TUBB2A for Human/Mouse/Rat |
Record No:42
| ACCESS NO | 100571 |
| GENE | TTC18 |
| DESCRIPTION | tetratricopeptide repeat (TPR) |
| NCBI ENTREZ ACCESS NO | 118491 |
| UNIPROT ACCESS NO | Q5T0N1 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | CD3+T cell |
| TECHNIQUES | 2D PAGE and MALDI-TOF-MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Decreased in asthmatic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17550934 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:43
| ACCESS NO | 100603 |
| GENE | TUBA1A |
| DESCRIPTION | Tubulin alpha 1 chain |
| NCBI ENTREZ ACCESS NO | 7846 |
| UNIPROT ACCESS NO | Q71U36 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | structural protein involved in airway remodelling |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | BE0001340 |
| MONCLONAL ANTIBODY | Anti-TUBA1A for Human/Mouse |
Record No:44
| ACCESS NO | 100642 |
| GENE | TF |
| DESCRIPTION | Transferrin |
| NCBI ENTREZ ACCESS NO | 7018 |
| UNIPROT ACCESS NO | P02787 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Seasonal allergic rhinitis(Patients treated with glucocorticoids for biomarker identification) |
| SAMPLE | Nasal fluid |
| TECHNIQUES | Quantitative proteomic analysis through LC/MSMS an |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Enriched in acute phase response pathway. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21887273 |
| DRUG TARGET | BE0000510 |
| MONCLONAL ANTIBODY | Anti-Transferrin for Rabbit/Human/Pig |
Record No:45
| ACCESS NO | 100671 |
| GENE | Tubb5 |
| DESCRIPTION | Tubulin beta 5 |
| NCBI ENTREZ ACCESS NO | 22154 |
| UNIPROT ACCESS NO | P99024 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in chronic asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:46
| ACCESS NO | 100678 |
| GENE | Tst |
| DESCRIPTION | Thiosulfate sulfurtransferase |
| NCBI ENTREZ ACCESS NO | 22117 |
| UNIPROT ACCESS NO | P52196 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in allergen induced asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | BE0004455 |
| MONCLONAL ANTIBODY | Anti-TST for Human/Mouse/Rat |
Record No:47
| ACCESS NO | 100683 |
| GENE | Tuba1c |
| DESCRIPTION | Tubulin alpha 6 |
| NCBI ENTREZ ACCESS NO | 22146 |
| UNIPROT ACCESS NO | P68373 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin |
| SAMPLE | Lung tissue |
| TECHNIQUES | MALDI Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in allergen induced asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21751807 |
| DRUG TARGET | BE0001388 |
| MONCLONAL ANTIBODY | Anti-TUBA6 for Human |
Record No:48
| ACCESS NO | 100724 |
| GENE | TF |
| DESCRIPTION | Transferrin |
| NCBI ENTREZ ACCESS NO | 7018 |
| UNIPROT ACCESS NO | P02787 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Blood plasma |
| TECHNIQUES | MALDI TOF MS and LC-MS/MS and Western Blot |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in atopic dermatitis patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19116453 |
| DRUG TARGET | BE0000510 |
| MONCLONAL ANTIBODY | Anti-Transferrin for Rabbit/Human/Pig |
Record No:49
| ACCESS NO | 100735 |
| GENE | TTR |
| DESCRIPTION | Transthyretin |
| NCBI ENTREZ ACCESS NO | 7276 |
| UNIPROT ACCESS NO | P02766 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma challenged with inhaled allergens |
| SAMPLE | Blood plasma |
| TECHNIQUES | 2D gel and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in immediate phase reaction of allergic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19076930 |
| DRUG TARGET | BE0000337 |
| MONCLONAL ANTIBODY | Anti-Prealbumin for Human |
Record No:50
| ACCESS NO | 100740 |
| GENE | TRIM 37 |
| DESCRIPTION | tripartite motif containing 37 |
| NCBI ENTREZ ACCESS NO | 4591 |
| UNIPROT ACCESS NO | O94972 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Perpheral blood mononuclear cells |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in developmental patterning and oncogenesis. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21966607 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:51
| ACCESS NO | 100764 |
| GENE | Tap1 |
| DESCRIPTION | Antigen peptide transporter 1 |
| NCBI ENTREZ ACCESS NO | 21354 |
| UNIPROT ACCESS NO | Q3TBA3 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after allergen challenge.Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | BE0003109 |
| MONCLONAL ANTIBODY | Anti-TAP1 for Human |
Record No:52
| ACCESS NO | 100768 |
| GENE | Topbp1 |
| DESCRIPTION | DNA topoisomerase II binding protein 1 |
| NCBI ENTREZ ACCESS NO | 235559 |
| UNIPROT ACCESS NO | Q6ZQF0 |
| ORGANISM | balb C mice |
| DISEASE PHENOTYPE | Allergic asthma after challenge with Aspergillus fumigatus |
| SAMPLE | Periferal blood monocytes |
| TECHNIQUES | Microarray (agilent) |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated after allergen challenge.Selected based on fold change. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20840155 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:53
| ACCESS NO | 100819 |
| GENE | Top2a |
| DESCRIPTION | DNA topoisomerase 2 alpha |
| NCBI ENTREZ ACCESS NO | 21973 |
| UNIPROT ACCESS NO | Q01320 |
| ORGANISM | BALB/c Mouse |
| DISEASE PHENOTYPE | Acute and chronic asthma |
| SAMPLE | Lung Tissue |
| TECHNIQUES | GeneChip Expression 3 (affymetrix) microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in mitosis and meiosis. Upregulated in short term and downregulted in long term allergen exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19028979 |
| DRUG TARGET | BE0000742 |
| MONCLONAL ANTIBODY | Anti-Topoisomerase II alpha for Human |
Record No:54
| ACCESS NO | 100897 |
| GENE | TNFRSF4 |
| DESCRIPTION | Tumor necrosis factor receptor superfamily member 4 |
| NCBI ENTREZ ACCESS NO | 7293 |
| UNIPROT ACCESS NO | P43489 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Seasonal allergic rhinitis |
| SAMPLE | Periferal blood mononuclear cells |
| TECHNIQUES | Gene chip (affymetrix) Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Helps to inhibit apoptosis in T cells and increase Th2 proliferation and its expression was highly upregulated in allergen challenged cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16826235 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD134 for Mouse/Human |
Record No:55
| ACCESS NO | 100898 |
| GENE | TNFSF7 |
| DESCRIPTION | TNFSF7 |
| NCBI ENTREZ ACCESS NO | 970 |
| UNIPROT ACCESS NO | P32970 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Seasonal allergic rhinitis |
| SAMPLE | Periferal blood mononuclear cells |
| TECHNIQUES | Gene chip (affymetrix) Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Increase T cell proliferation and enhanced in allergic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16826235 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD70 for Mouse/Human |
Record No:56
| ACCESS NO | 100899 |
| GENE | TNFRSF1B |
| DESCRIPTION | Tumor necrosis factor receptor superfamily member 1B |
| NCBI ENTREZ ACCESS NO | 7133 |
| UNIPROT ACCESS NO | P20333 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Seasonal allergic rhinitis |
| SAMPLE | Periferal blood mononuclear cells |
| TECHNIQUES | Gene chip (affymetrix) Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Increase T cell proliferation and enhanced in allergic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16826235 |
| DRUG TARGET | BE0000949 |
| MONCLONAL ANTIBODY | Anti-TNF Receptor II for Mouse/Rat/Human |
Record No:57
| ACCESS NO | 100922 |
| GENE | Timp1 |
| DESCRIPTION | Tissue inhibitor of metalloproteinase 1 |
| NCBI ENTREZ ACCESS NO | 21857 |
| UNIPROT ACCESS NO | P12032 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Plays a pivotal role in degradation of extracellular matrix and tissue remodelling during inflammation. Highly upregulated in all three food allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TIMP1 for Human |
Record No:58
| ACCESS NO | 100929 |
| GENE | Tpm2 |
| DESCRIPTION | Tropomyosin 2 beta |
| NCBI ENTREZ ACCESS NO | 22004 |
| UNIPROT ACCESS NO | Q6PJ18 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after induction with food allergens. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Tropomyosin for Mouse/Rat/Human |
Record No:59
| ACCESS NO | 100932 |
| GENE | Tmem16a |
| DESCRIPTION | Transmembrane protein 16A |
| NCBI ENTREZ ACCESS NO | 101772 |
| UNIPROT ACCESS NO | Q8BHY3 |
| ORGANISM | BALB/C mice |
| DISEASE PHENOTYPE | Food allergy caused by Beta lactoglobulin Ovalbumin and peanut agglutinin |
| SAMPLE | Mesenteric lymph node |
| TECHNIQUES | cDNA microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after induction with food allergens. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21211037 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TMEM16A for Mouse/Human |
Record No:60
| ACCESS NO | 100975 |
| GENE | Tslp |
| DESCRIPTION | Thymic stromal lymphopoietin |
| NCBI ENTREZ ACCESS NO | 53603 |
| UNIPROT ACCESS NO | Q9JIE6 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic diseases and effect of dibutyl phthalate (DBP) |
| SAMPLE | Ear tissue |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased expression of TSLP is the reason for aggravation effect of skin inflammation induced by DBP. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24498391 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TSLP for Human |
Record No:61
| ACCESS NO | 101021 |
| GENE | TFF3 |
| DESCRIPTION | Trefoil factor 3 |
| NCBI ENTREZ ACCESS NO | 7033 |
| UNIPROT ACCESS NO | Q07654 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It shows highest expression in patients with eosinophilic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Trefoil Factor 3 for Human |
Record No:62
| ACCESS NO | 101022 |
| GENE | TNFAIP3 |
| DESCRIPTION | TNF-a induced protein 3 |
| NCBI ENTREZ ACCESS NO | 7128 |
| UNIPROT ACCESS NO | P21580 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is a biomarkers of neutrophilic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TNFAIP3 for Human |
Record No:63
| ACCESS NO | 101023 |
| GENE | TNFRSF1B |
| DESCRIPTION | TNF receptor superfamily - member 1B |
| NCBI ENTREZ ACCESS NO | 7133 |
| UNIPROT ACCESS NO | P20333 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is a biomarkers of neutrophilic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | BE0000949 |
| MONCLONAL ANTIBODY | N/A |
Record No:64
| ACCESS NO | 101024 |
| GENE | TNFSF14 |
| DESCRIPTION | TNF (ligand) superfamily - member 14 |
| NCBI ENTREZ ACCESS NO | 8740 |
| UNIPROT ACCESS NO | O43557 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma with eosinophilic and neutrophilic inflammation |
| SAMPLE | Sputum |
| TECHNIQUES | Microarray and qPCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene is commonly expresed significantly at high level in all kinds of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24582314 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LIGHT for Human |
Record No:65
| ACCESS NO | 101042 |
| GENE | TPM4 |
| DESCRIPTION | Tropomyosin alpha-4 chain |
| NCBI ENTREZ ACCESS NO | 7171 |
| UNIPROT ACCESS NO | P67936 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic eczema (AE) |
| SAMPLE | Vernix |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is strongly down regulated in atopic eczema. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24205894 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TPM4 [EPR13316] for Mouse/Rat/Human |
Record No:66
| ACCESS NO | 101088 |
| GENE | Tgfb (TGF- beta) |
| DESCRIPTION | TGF beta binding protein |
| NCBI ENTREZ ACCESS NO | 268977 |
| UNIPROT ACCESS NO | Q8CG19 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Allergic disorder and prebiotics induced tolerance |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein is highly expressed after allergen sensitization in prebiotic-fed mice. It is related to tolerance and would play a crucial role in the prevention of allergy. Perinatal and postweaning exposure to prebiotics is very encouraging because it allows the induction of several tolerance-related biomarkers |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | BE0003782 |
| MONCLONAL ANTIBODY | Anti-TGFBI [EPR12078(B)] for Human/Mouse/Rat |
Record No:67
| ACCESS NO | 101123 |
| GENE | TGM2 |
| DESCRIPTION | Transglutaminase 2 |
| NCBI ENTREZ ACCESS NO | 7052 |
| UNIPROT ACCESS NO | P21980 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Macrophage from blood and sputum |
| TECHNIQUES | Mass spectrometry and immunoblot |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | This gene along with other markers such as MRC1 and CD68 may help to clarify alternative activation heterogeneity of macrophage(local or systemic) in lung tissue. It is a potential marker of IL-4 stimulation and a tool to stratify asthmatic patients by FACS analysis of fresh blood or sputum. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23293084 |
| DRUG TARGET | BE0001035 |
| MONCLONAL ANTIBODY | Anti-Transglutaminase 2 for Mouse/Human |
Record No:68
| ACCESS NO | 101131 |
| GENE | TIMP1 |
| DESCRIPTION | issue inhibitor of metalloproteinase-1 |
| NCBI ENTREZ ACCESS NO | 7076 |
| UNIPROT ACCESS NO | P01033 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Genomic DNA and serum |
| TECHNIQUES | Genotyping and ELISA |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | G3774A and Phe124Phe of TIMP-1 in this gene was identified as important genetic markers for use in better management of the disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23226977 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TIMP1Â for Human |
Record No:69
| ACCESS NO | 101132 |
| GENE | Tacr1 (NK1-R) |
| DESCRIPTION | Tachykinin substance P |
| NCBI ENTREZ ACCESS NO | 21336 |
| UNIPROT ACCESS NO | P30548 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | NK1-R blockade improved obesity related biomarkers and as well as allergen sensitization and bronchial inflammation. These positive effects support a common pathway in the obese-asthma phenotype and highlight SP as a target with potential clinical interest in the obese-asthma epidemics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23176443 |
| DRUG TARGET | BE0000384 |
| MONCLONAL ANTIBODY | N/A |
Record No:70
| ACCESS NO | 101172 |
| GENE | TFRC (CD71) |
| DESCRIPTION | Transferrin receptor |
| NCBI ENTREZ ACCESS NO | 7037 |
| UNIPROT ACCESS NO | P02786 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
| SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
| TECHNIQUES | Label free nano-LC-MS/MS and western blot |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is a marker of effector dendritic cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22464673 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Transferrin Receptor for Mouse/Rat/Human |
Record No:71
| ACCESS NO | 101175 |
| GENE | TRAF1 |
| DESCRIPTION | TNF receptor-associated factor 1 |
| NCBI ENTREZ ACCESS NO | 7185 |
| UNIPROT ACCESS NO | Q13077 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
| SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
| TECHNIQUES | Label free nano-LC-MS/MS and western blot |
| OMICS | Proteomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | It is a marker of effector dendritic cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22464673 |
| DRUG TARGET | BE0000949 |
| MONCLONAL ANTIBODY | N/A |
Record No:72
| ACCESS NO | 101176 |
| GENE | TSC22D3 (GILZ) |
| DESCRIPTION | Glucocorticoid-induced leucine zipper |
| NCBI ENTREZ ACCESS NO | 1831 |
| UNIPROT ACCESS NO | Q99576 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy and effect of grass pollen immunothrapy |
| SAMPLE | Dendritic cell subtypes (DC1/DC2/DC17/DCreg) |
| TECHNIQUES | qPCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | It is overexpressed in various types of tolerogenic dendritic cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22464673 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:73
| ACCESS NO | 101190 |
| GENE | TGFB1 |
| DESCRIPTION | Tansforming growth factor beta 1 |
| NCBI ENTREZ ACCESS NO | 7040 |
| UNIPROT ACCESS NO | P01137 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid and macrophage |
| TECHNIQUES | real-time PCR and immunoassay and fluorescent micr |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Children with severe asthma have increased airway TGF beta1 expression and activation associated with an increased airway oxidant burden. Oxidant stress may mediate the effects of TGF beta 1 and promote airway remodeling in children with severe asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22206775 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TGF beta 1 for Human |
Record No:74
| ACCESS NO | 101223 |
| GENE | TCF23 |
| DESCRIPTION | Transcription factor 23 |
| NCBI ENTREZ ACCESS NO | 150921 |
| UNIPROT ACCESS NO | Q7RTU1 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:75
| ACCESS NO | 101224 |
| GENE | TAPT1 |
| DESCRIPTION | Transmembrane anterior posterior transformation 1 |
| NCBI ENTREZ ACCESS NO | 202018 |
| UNIPROT ACCESS NO | Q6NXT6 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Food allergy |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | 2D-DIGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein was found to be down regulated in RAST+ subjects with severe food allergies. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22091390 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:76
| ACCESS NO | 101249 |
| GENE | Tslp |
| DESCRIPTION | Thymic stromal lymphopoietin |
| NCBI ENTREZ ACCESS NO | 53603 |
| UNIPROT ACCESS NO | Q9JIE6 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
| SAMPLE | Lung tissue |
| TECHNIQUES | real time PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Pretreatment with artesunate (30 mg/kg) demonstrated strong suppression of this cytokine responsible for initiation of Th2 immune response. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TSLP for Human |
Record No:77
| ACCESS NO | 101259 |
| GENE | Tsc2 |
| DESCRIPTION | Tuberin |
| NCBI ENTREZ ACCESS NO | 22084 |
| UNIPROT ACCESS NO | Q61037 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma and effct of the drug 'Artesunate' |
| SAMPLE | Lung tissue |
| TECHNIQUES | Immunoblot |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Artesunate markedly inhibited the EGF-induced phosphorylation of Akt. Thus EGF induced activation of inflammatory PI3K/Akt signaling pathway is suppressed. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:78
| ACCESS NO | 101277 |
| GENE | TPSAB1 |
| DESCRIPTION | Tryptase |
| NCBI ENTREZ ACCESS NO | 7177 |
| UNIPROT ACCESS NO | P20231 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma (The effect of aspirin desensitization) |
| SAMPLE | Sputum |
| TECHNIQUES | ImmunoCAP |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased significantly during aspirin desensitization. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20728206 |
| DRUG TARGET | BE0003736 |
| MONCLONAL ANTIBODY | Anti-Mast Cell Tryptase for Mouse/Rat/Human |
Record No:79
| ACCESS NO | 101280 |
| GENE | TIMP-1 |
| DESCRIPTION | TIMP metallopeptidase inhibitor 1 |
| NCBI ENTREZ ACCESS NO | 7076 |
| UNIPROT ACCESS NO | P01033 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma (The effect of aspirin desensitization) |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Inhibitor of matrix metalloprotease 9. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20728206 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TIMP1 for Human |
Record No:80
| ACCESS NO | 101291 |
| GENE | TNF- alpha |
| DESCRIPTION | Tumor necrosis factor alpha |
| NCBI ENTREZ ACCESS NO | 7124 |
| UNIPROT ACCESS NO | P01375 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma in children |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0000704 |
| MONCLONAL ANTIBODY | Anti-TNF alpha for Mouse/Human |
Record No:81
| ACCESS NO | 101303 |
| GENE | TIMP-1 |
| DESCRIPTION | Tissue inhibitor metalloproteinase-1 |
| NCBI ENTREZ ACCESS NO | 7076 |
| UNIPROT ACCESS NO | P01033 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Childhood asthma |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19788537 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TIMP1 for Human/Mouse |
Record No:82
| ACCESS NO | 101383 |
| GENE | Ttr |
| DESCRIPTION | Transthyretin |
| NCBI ENTREZ ACCESS NO | 22139 |
| UNIPROT ACCESS NO | P07309 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Reduced expression in chronically asthmatic mouse. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | BE0000337 |
| MONCLONAL ANTIBODY | Anti-Prealbumin for Human |
Record No:83
| ACCESS NO | 101389 |
| GENE | Trf |
| DESCRIPTION | Transferrin |
| NCBI ENTREZ ACCESS NO | 22041 |
| UNIPROT ACCESS NO | Q921I1 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Chronic Asthma |
| SAMPLE | Lung Tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | MALDI Tof/Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in chronic asthma model. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18594147 |
| DRUG TARGET | BE0000510 |
| MONCLONAL ANTIBODY | Anti-Transferrin for Rabbit/Human/Pig |
Record No:84
| ACCESS NO | 101402 |
| GENE | Tnf |
| DESCRIPTION | Tumor necrosis factor |
| NCBI ENTREZ ACCESS NO | 21926 |
| UNIPROT ACCESS NO | P06804 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0000704 |
| MONCLONAL ANTIBODY | Anti-TNF for Mouse/ Human/ Chimpanzee |
Record No:85
| ACCESS NO | 101403 |
| GENE | Tnfrsf9 |
| DESCRIPTION | Tumor necrosis factor receptor superfamily member 9 |
| NCBI ENTREZ ACCESS NO | 21942 |
| UNIPROT ACCESS NO | Q8R037 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD137 for Human |
Record No:86
| ACCESS NO | 101405 |
| GENE | Timp1 |
| DESCRIPTION | Tissue inhibitor of metalloproteinase 1 |
| NCBI ENTREZ ACCESS NO | 21857 |
| UNIPROT ACCESS NO | P12032 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3hours and 12 hours of allergen induction in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TIMP1 for Mouse/Human |
Record No:87
| ACCESS NO | 101410 |
| GENE | Trem1 |
| DESCRIPTION | Triggering receptor expressed on myeloid cells 1 |
| NCBI ENTREZ ACCESS NO | 58217 |
| UNIPROT ACCESS NO | Q9JKE2 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Leads to increased signalling of inflammatory mediators. Upregulated after 3hours and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0001288 |
| MONCLONAL ANTIBODY | Anti-TREM1 for Human |
Record No:88
| ACCESS NO | 101431 |
| GENE | Tnfrsf1b |
| DESCRIPTION | Tumor necrosis factor receptor superfamily member 1b |
| NCBI ENTREZ ACCESS NO | 21938 |
| UNIPROT ACCESS NO | P25119 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0000949 |
| MONCLONAL ANTIBODY | Anti-Soluble TNF Receptor II for Human |
Record No:89
| ACCESS NO | 101438 |
| GENE | Tnfaip2 |
| DESCRIPTION | Tumor necrosis factor alpha-induced protein 2 |
| NCBI ENTREZ ACCESS NO | 21928 |
| UNIPROT ACCESS NO | Q61333 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:90
| ACCESS NO | 101451 |
| GENE | Tgm1 |
| DESCRIPTION | Transglutaminase 1 |
| NCBI ENTREZ ACCESS NO | 21816 |
| UNIPROT ACCESS NO | Q9JLF6 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3hours and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0002241 |
| MONCLONAL ANTIBODY | Anti-TGM1 for Human |
Record No:91
| ACCESS NO | 101472 |
| GENE | Tmem173 |
| DESCRIPTION | Transmembrane protein 173 |
| NCBI ENTREZ ACCESS NO | 72512 |
| UNIPROT ACCESS NO | Q3TBT3 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Overexpressed after 3hours and 12 hours of allergenic mould extract challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TMEM173 for Human |
Record No:92
| ACCESS NO | 101481 |
| GENE | Tlr2 |
| DESCRIPTION | Toll-like receptor 2 |
| NCBI ENTREZ ACCESS NO | 24088 |
| UNIPROT ACCESS NO | Q9QUN7 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of fungal allergen challenge in asthmatic mice. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | BE0001164 |
| MONCLONAL ANTIBODY | Anti-TLR2 for Mouse/Human/Rat |
Record No:93
| ACCESS NO | 101498 |
| GENE | Tnfsf9 |
| DESCRIPTION | Tumor necrosis factor (ligand) superfamily member 9 |
| NCBI ENTREZ ACCESS NO | 21950 |
| UNIPROT ACCESS NO | P41274 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TNFSF9 for Human |
Record No:94
| ACCESS NO | 101499 |
| GENE | Thbs1 |
| DESCRIPTION | Thrombospondin 1 |
| NCBI ENTREZ ACCESS NO | 21825 |
| UNIPROT ACCESS NO | Q80YQ1 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Thrombospondin for Mouse/Rat/Human |
Record No:95
| ACCESS NO | 101503 |
| GENE | Tfpi2 |
| DESCRIPTION | Tissue factor pathway inhibitor 2 |
| NCBI ENTREZ ACCESS NO | 21789 |
| UNIPROT ACCESS NO | O35536 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TFPI2 for Mouse/Rat/Human |
Record No:96
| ACCESS NO | 101505 |
| GENE | Trex1 |
| DESCRIPTION | Three prime repair exonuclease 1 |
| NCBI ENTREZ ACCESS NO | 22040 |
| UNIPROT ACCESS NO | Q91XB0 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TREX1 for Mouse/Rat/Human |
Record No:97
| ACCESS NO | 101522 |
| GENE | Trib1 |
| DESCRIPTION | Tribbles homolog 1 |
| NCBI ENTREZ ACCESS NO | 211770 |
| UNIPROT ACCESS NO | Q8K4K4 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TRIB1 for Human |
Record No:98
| ACCESS NO | 101524 |
| GENE | Tnfaip8l1 |
| DESCRIPTION | Tumor necrosis factor alpha-induced protein 8-like 1 |
| NCBI ENTREZ ACCESS NO | 66443 |
| UNIPROT ACCESS NO | Q8K288 |
| ORGANISM | Female BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma (Immunological charecterization after exposure to Metarhizium anisopliae(MACA)compar |
| SAMPLE | Lung Tissue |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated after 3 and 12 hours of allergen induction in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20045013 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:99
| ACCESS NO | 101541 |
| GENE | TNF-alpha |
| DESCRIPTION | Tumor necrosis factor alpha |
| NCBI ENTREZ ACCESS NO | 7124 |
| UNIPROT ACCESS NO | P01375 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by Virus |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expressed in virus induced asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17628646 |
| DRUG TARGET | BE0000704 |
| MONCLONAL ANTIBODY | Anti-TNF alpha for Mouse/Human |
Record No:100
| ACCESS NO | 101553 |
| GENE | TLR2 |
| DESCRIPTION | Toll-like receptor 2 |
| NCBI ENTREZ ACCESS NO | 24088 |
| UNIPROT ACCESS NO | Q9QUN7 |
| ORGANISM | Dendritic cell culture |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Dendritic cell culture |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Expression decreased after particulate air pollutant challenge inferring suppressed immunity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19662206 |
| DRUG TARGET | BE0001164 |
| MONCLONAL ANTIBODY | Anti-TLR2 for Mouse/Human/Rat |
Record No:101
| ACCESS NO | 101554 |
| GENE | TLR4 |
| DESCRIPTION | Toll-like receptor 4 |
| NCBI ENTREZ ACCESS NO | 21898 |
| UNIPROT ACCESS NO | Q9QUK6 |
| ORGANISM | Dendritic cell culture |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Dendritic cell culture |
| TECHNIQUES | RT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| COMMENTS | Expression decreased after particulate air pollutant challenge inferring suppressed immunity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19662206 |
| DRUG TARGET | BE0002442 |
| MONCLONAL ANTIBODY | Anti-TLR4 for Mouse/Rat/Human |
Record No:102
| ACCESS NO | 101559 |
| GENE | TFF2 |
| DESCRIPTION | Trefoil factor 2 |
| NCBI ENTREZ ACCESS NO | 21785 |
| UNIPROT ACCESS NO | Q9QX97 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in mucus production and its expression is dependant on IL 13 and STAT 6 signalling. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | BE0004464 |
| MONCLONAL ANTIBODY | N/A |
Record No:103
| ACCESS NO | 101609 |
| GENE | Tkt |
| DESCRIPTION | Transketolase |
| NCBI ENTREZ ACCESS NO | 21881 |
| UNIPROT ACCESS NO | P40142 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Involved in metabolism and expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | BE0004301 |
| MONCLONAL ANTIBODY | Anti-Transketolase for Human |
Record No:104
| ACCESS NO | 101622 |
| GENE | Tcn2 |
| DESCRIPTION | Transcobalamin 2 |
| NCBI ENTREZ ACCESS NO | 21452 |
| UNIPROT ACCESS NO | O88968 |
| ORGANISM | Balb/C wild-type mice |
| DISEASE PHENOTYPE | Allergic asthma induced by both Ovalbumin and mIL-13 |
| SAMPLE | Lung tissue |
| TECHNIQUES | Gene Chip microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Expressed after IL 13 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16402082 |
| DRUG TARGET | BE0000362 |
| MONCLONAL ANTIBODY | Anti-TCN2 for Human |
Record No:105
| ACCESS NO | 101648 |
| GENE | Ttr |
| DESCRIPTION | Transthyretin |
| NCBI ENTREZ ACCESS NO | 22139 |
| UNIPROT ACCESS NO | P07309 |
| ORGANISM | Male BALB/c mice |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Lung tissue |
| TECHNIQUES | 2D electrophoresis and MALDI Tof Tof |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 16100447 |
| DRUG TARGET | BE0000337 |
| MONCLONAL ANTIBODY | Anti-Prealbumin for Human |
Record No:106
| ACCESS NO | 101674 |
| GENE | Tnfaip6 (TSG-6) |
| DESCRIPTION | TNF-stimulated gene-6 |
| NCBI ENTREZ ACCESS NO | 21930 |
| UNIPROT ACCESS NO | O08859 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma induced by Ovalbumin challenge |
| SAMPLE | Lung tissue and Broncho Alveolar Lavage (BAL) cell |
| TECHNIQUES | Immunoassay (ELISA and Immunohistochemistry) and B |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | TSG-6 is dispensable for the induction of Th2 immunity but is essential for the robust increase in pulmonary Hyaluronan deposition and propagation of acute eosinophilic pulmonary inflammation. In TSG-6 knock out mice the lack of TSG-6 results in diminished HA accumulation and decreased inflammation and airway hyperresponsiveness. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23118230 |
| DRUG TARGET | BE0004641 |
| MONCLONAL ANTIBODY | N/A |
Record No:107
| ACCESS NO | 101694 |
| GENE | Trapa1 |
| DESCRIPTION | Transient receptor potential cation channel subfamily 1 |
| NCBI ENTREZ ACCESS NO | 277328 |
| UNIPROT ACCESS NO | Q8BLA8 |
| ORGANISM | Mouse |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Lung tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | Immunoassay and real time PCR |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Genetic ablation of TRPA1 inhibited allergen-induced leukocyte infiltration in the airways and abolished airway hyperreactivity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19458046 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TAPA1 [M38] for Rabbit/Human |
Record No:108
| ACCESS NO | 101695 |
| GENE | TBX21 |
| DESCRIPTION | T-bet (T-box expressed in T cells) |
| NCBI ENTREZ ACCESS NO | 30009 |
| UNIPROT ACCESS NO | Q9UL17 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma |
| SAMPLE | Genomic DNA |
| TECHNIQUES | Genotyping by SEQUENOM MassARRAYMALDI-TOF |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | T-bet knockout mouse spontaneously develops airway hyperresponsiveness and other changes consistent with asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15604153 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-T-bet / Tbx21 [4B10] for Mouse/Human |
Record No:109
| ACCESS NO | 101731 |
| GENE | TIMP1 |
| DESCRIPTION | Tissue inhibitor of metalloproteinases |
| NCBI ENTREZ ACCESS NO | 7076 |
| UNIPROT ACCESS NO | P01033 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protease inhibitor is upregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TIMP1 [102D1] for Human |
Record No:110
| ACCESS NO | 101735 |
| GENE | TKT |
| DESCRIPTION | Transketolase |
| NCBI ENTREZ ACCESS NO | 7086 |
| UNIPROT ACCESS NO | P29401 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TKTL2 [EPR8592] for Mouse/Rat/Human |
Record No:111
| ACCESS NO | 101745 |
| GENE | TXN |
| DESCRIPTION | Thioredoxin (surface-associated sulfhydryl protein) |
| NCBI ENTREZ ACCESS NO | 7295 |
| UNIPROT ACCESS NO | H9ZYJ2 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TXNRD1 [EPNCIR129] for Mouse/Rat/Human |
Record No:112
| ACCESS NO | 101751 |
| GENE | TXNDC17 |
| DESCRIPTION | Protein thioredoxin-like 5 |
| NCBI ENTREZ ACCESS NO | 84817 |
| UNIPROT ACCESS NO | I3L0K2 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:113
| ACCESS NO | 101762 |
| GENE | THBS1 |
| DESCRIPTION | Thrombospondin 1 |
| NCBI ENTREZ ACCESS NO | 7057 |
| UNIPROT ACCESS NO | P07996 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This local matrix protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Thrombospondin [A6.1] for Mouse/Rat/Human |
Record No:114
| ACCESS NO | 101801 |
| GENE | THBS4 |
| DESCRIPTION | Thrombospondin 4 |
| NCBI ENTREZ ACCESS NO | 7060 |
| UNIPROT ACCESS NO | P35443 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This serum protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:115
| ACCESS NO | 101802 |
| GENE | TUBB4B |
| DESCRIPTION | Tubulin #-2 chain |
| NCBI ENTREZ ACCESS NO | 10383 |
| UNIPROT ACCESS NO | P68371 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma induced by allergen challenge |
| SAMPLE | Broncho Alveolar Lavage (BAL) Fluid |
| TECHNIQUES | LC-MS/MS |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This cytoskeletal protein is up regulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15951573 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:116
| ACCESS NO | 101854 |
| GENE | TGFBR3 |
| DESCRIPTION | Transforming growth factor- beta receptor III |
| NCBI ENTREZ ACCESS NO | 7049 |
| UNIPROT ACCESS NO | Q03167 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic Rhinitis induced by pollen allergen |
| SAMPLE | Nasal lavage fluids |
| TECHNIQUES | Affymetrix microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | This anti inflammatory gene showed lower expression levels in patients than in controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15836756 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:117
| ACCESS NO | 101863 |
| GENE | TF |
| DESCRIPTION | Transferrin |
| NCBI ENTREZ ACCESS NO | 7018 |
| UNIPROT ACCESS NO | P02787 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Plasma |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is down regulated in atopic dermatitis patient. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19116453 |
| DRUG TARGET | BE0000510 |
| MONCLONAL ANTIBODY | Anti-Transferrin for Rabbit and Human |
Record No:118
| ACCESS NO | 101881 |
| GENE | TRIOBP |
| DESCRIPTION | TRIO and F-actin binding protein |
| NCBI ENTREZ ACCESS NO | 11078 |
| UNIPROT ACCESS NO | Q9H2D6 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Fibroblast |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic fibroblasts comparative to normal fibroblasts. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15468290 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TRIOBP for Human |
Record No:119
| ACCESS NO | 101885 |
| GENE | TNF (TNF- alpha) |
| DESCRIPTION | Tumor necrosis factor |
| NCBI ENTREZ ACCESS NO | 7124 |
| UNIPROT ACCESS NO | Q8MKG8 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Fibroblast |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic fibroblasts comparative to normal fibroblasts. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15468290 |
| DRUG TARGET | BE0000704 |
| MONCLONAL ANTIBODY | Anti-TNF alpha for Mouse/Human |
Record No:120
| ACCESS NO | 101889 |
| GENE | TPM3 |
| DESCRIPTION | Tropomyosin alpha 3 chain |
| NCBI ENTREZ ACCESS NO | 7170 |
| UNIPROT ACCESS NO | P06753 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Fibroblast |
| TECHNIQUES | 2D-PAGE and MALDI-TOF/TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is down regulated in atopic fibroblasts comparative to normal fibroblasts. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15468290 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Tropomyosin for Mouse/Rat/Human |
Record No:121
| ACCESS NO | 101904 |
| GENE | TXK |
| DESCRIPTION | Tyrosine protein kinase TXK |
| NCBI ENTREZ ACCESS NO | 7294 |
| UNIPROT ACCESS NO | P42681 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic dermatitis |
| SAMPLE | Peripheral blood eosinophils |
| TECHNIQUES | 2DE-PAGE and MALDI-TOF |
| OMICS | Proteomics |
| STUDY | High Throughput |
| COMMENTS | This protein is upregulated in atopic dermatitis patients eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 15832365 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TXK for Human |
Record No:122
| ACCESS NO | 101960 |
| GENE | TAPBP |
| DESCRIPTION | TAP binding protein |
| NCBI ENTREZ ACCESS NO | 6892 |
| UNIPROT ACCESS NO | O15533 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Upregulated in asthmatic children. Involved in cellular function and maintenance. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:123
| ACCESS NO | 101965 |
| GENE | TIPRL |
| DESCRIPTION | TIP41 TOR signalling pathway regulator-like |
| NCBI ENTREZ ACCESS NO | 261726 |
| UNIPROT ACCESS NO | O75663 |
| ORGANISM | Human(Asthmatic children) |
| DISEASE PHENOTYPE | Asthma( Mite sensitized asthma) |
| SAMPLE | Peripheral Blood Mononuclear Cells |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19187333 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:124
| ACCESS NO | 101971 |
| GENE | TGF-beta |
| DESCRIPTION | Tumour growth factor Beta |
| NCBI ENTREZ ACCESS NO | 7040 |
| UNIPROT ACCESS NO | P01137 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergy (Immunotherapy of pollen allergy) |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Flow cytometry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased after specific immunotherapy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24834772 |
| DRUG TARGET | BE0000984 |
| MONCLONAL ANTIBODY | Anti-TGF beta 1 for Mouse/Rat/Human |
Record No:125
| ACCESS NO | 101990 |
| GENE | TFRC |
| DESCRIPTION | Transferrin receptor |
| NCBI ENTREZ ACCESS NO | 7037 |
| UNIPROT ACCESS NO | P02786 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Asthma and allergic rhinitis |
| SAMPLE | Epithelial cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in patients with allergic rhinitis with or without asthma in the upper airways. |
| GEO_PRIDE_ACCESS_NO | GSE51392 |
| REFERENCE | 24475887 |
| DRUG TARGET | BE0004850 |
| MONCLONAL ANTIBODY | Anti-Transferrin for Mouse/Rat/Human |
Record No:126
| ACCESS NO | 102047 |
| GENE | TSPAN1 |
| DESCRIPTION | Tetraspanin 1 |
| NCBI ENTREZ ACCESS NO | 10103 |
| UNIPROT ACCESS NO | O60635 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:127
| ACCESS NO | 102061 |
| GENE | TBC1D4 |
| DESCRIPTION | TBC1 domain family member 4 |
| NCBI ENTREZ ACCESS NO | 9882 |
| UNIPROT ACCESS NO | O60343 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Nasal epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Highly expressed in patients with allergic rhinitis and asthma. (Data in supplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TBC1D4 for human |
Record No:128
| ACCESS NO | 102063 |
| GENE | TIMP2 |
| DESCRIPTION | TIMP metallopeptidase inhibitor 2 |
| NCBI ENTREZ ACCESS NO | 7077 |
| UNIPROT ACCESS NO | P16035 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic rhinitis and asthma |
| SAMPLE | Primary nasal and bronchial epithelial cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Dowregulated in upper airways(data in suplimentary table). |
| GEO_PRIDE_ACCESS_NO | GSE44037 |
| REFERENCE | 24282527 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TIMP2 for Mouse/Rat/Rabbit/Human |
Record No:129
| ACCESS NO | 102084 |
| GENE | TPP2 |
| DESCRIPTION | Tripeptidyl peptidase II |
| NCBI ENTREZ ACCESS NO | 7174 |
| UNIPROT ACCESS NO | P29144 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in ubiquitin-proteasome pathway. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Tripeptidyl peptidase II for Mouse/Rat/Human |
Record No:130
| ACCESS NO | 102097 |
| GENE | TBC1D1 |
| DESCRIPTION | TBC1 domain family member 1 |
| NCBI ENTREZ ACCESS NO | 23216 |
| UNIPROT ACCESS NO | Q86TI0 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Differentially expressed in asthma. Involved in signal transduction. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:131
| ACCESS NO | 102120 |
| GENE | TIAM1 |
| DESCRIPTION | T-cell lymphoma invasion and metastasis 1 |
| NCBI ENTREZ ACCESS NO | 7074 |
| UNIPROT ACCESS NO | Q13009 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray and real time PCR |
| OMICS | Genomics |
| STUDY | High Throughput and Low Throughput |
| COMMENTS | Upregulated in atopic asthma. Involved in Treg expression and function. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:132
| ACCESS NO | 102126 |
| GENE | TSC22D3 |
| DESCRIPTION | TSC22 domain family member 3 |
| NCBI ENTREZ ACCESS NO | 1831 |
| UNIPROT ACCESS NO | Q99576 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Atopic asthma |
| SAMPLE | CD4+ T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Differentialy expressed in asthma. Involved in transcriptional regulation. |
| GEO_PRIDE_ACCESS_NO | GSE14908 |
| REFERENCE | 19414752 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-GilZ / TilZ for Mouse/Human |
Record No:133
| ACCESS NO | 102150 |
| GENE | TCF21 |
| DESCRIPTION | Transcription factor 21 |
| NCBI ENTREZ ACCESS NO | 6943 |
| UNIPROT ACCESS NO | O43680 |
| ORGANISM | Human |
| DISEASE PHENOTYPE | Allergic asthma |
| SAMPLE | Bronchial Biopsy |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| COMMENTS | Downregulated in allergic asthma. |
| GEO_PRIDE_ACCESS_NO | GSE41649 |
| REFERENCE | 19842841 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TCF21 for Human |