BROWSE RESULT OF Others
| 225 Records |
| ACCESS NO | 100397 |
| GENE | EPX |
| DESCRIPTION | Eosinophil peroxidase |
| NCBI ENTREZ ACCESS NO | 8288 |
| UNIPROT ACCESS NO | P11678 |
| ORGANISM | Human |
| SAMPLE | sputum eosinophils |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is specific surrogate marker of eosinophil degranulation and airway eosinophilia. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23931643 |
| DRUG TARGET | BE0003555 |
| MONCLONAL ANTIBODY | Anti-EPX for Human |
Record No:2
| ACCESS NO | 100402 |
| GENE | MMP9 |
| DESCRIPTION | Matrix metalloproteinase (MMP)-9 |
| NCBI ENTREZ ACCESS NO | 4318 |
| UNIPROT ACCESS NO | P14780 |
| ORGANISM | Human |
| SAMPLE | Plasma |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This gene mainly contributes to inflammatory responses. It also plays a significant role in subsequent tissue remodelling and repair. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19317840 |
| DRUG TARGET | BE0000058 |
| MONCLONAL ANTIBODY | Anti-MMP9 for Mouse/Rat/Human |
Record No:3
| ACCESS NO | 100945 |
| GENE | Alox12 |
| DESCRIPTION | Arachidonate 12-lipoxygenase |
| NCBI ENTREZ ACCESS NO | 11684 |
| UNIPROT ACCESS NO | P39655 |
| ORGANISM | balb/c mice |
| SAMPLE | Broncho Alveolar Lavage (BALF) fluid |
| TECHNIQUES | Western blot and ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Causes epithelial injury in asthma pathogenesis. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23528921 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:4
| ACCESS NO | 100946 |
| GENE | MCP3 |
| DESCRIPTION | Monocyte chemotactic protein |
| NCBI ENTREZ ACCESS NO | 6354 |
| UNIPROT ACCESS NO | P80098 |
| ORGANISM | Human |
| SAMPLE | Genomic DNA from Peripheral blood leukocytes |
| TECHNIQUES | PCR and Electrophoretic mobility shift assay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Promoter polymorphism is associated with asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21388664 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-MCP3 for Rat/Human |
Record No:5
| ACCESS NO | 100947 |
| GENE | Sap |
| DESCRIPTION | Serum amyloid P |
| NCBI ENTREZ ACCESS NO | 20219 |
| UNIPROT ACCESS NO | P12246 |
| ORGANISM | Female C57BL/6 mouse |
| SAMPLE | Lung tissue |
| TECHNIQUES | Immunohistochemistry and RT-PCR |
| OMICS | others |
| STUDY | Low Throughput |
| COMMENTS | An important inhibitor of macrophage differentiation.Protects against fungal spore induced allergy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20673988 |
| DRUG TARGET | BE0001213 |
| MONCLONAL ANTIBODY | N/A |
Record No:6
| ACCESS NO | 100948 |
| GENE | YKL40 |
| DESCRIPTION | Chitinase-like protein |
| NCBI ENTREZ ACCESS NO | 1116 |
| UNIPROT ACCESS NO | P36222 |
| ORGANISM | Human |
| SAMPLE | Bronchial smooth muscle |
| TECHNIQUES | Imunohistochemistry and ELISA and Western Blot |
| OMICS | others |
| STUDY | Low Throughput |
| COMMENTS | Promotes Bronchial smooth muscle cell proliferation and migration with the help of protease activated receptor(PAR2) dependant mechanism. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22281830 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CHI3L1 for Human |
Record No:7
| ACCESS NO | 100949 |
| GENE | IL7 |
| DESCRIPTION | Interleukin 7 |
| NCBI ENTREZ ACCESS NO | 3574 |
| UNIPROT ACCESS NO | P13232 |
| ORGANISM | Human |
| SAMPLE | Eosinophils from Peripheral blood |
| TECHNIQUES | Western blotting Flow cytometry ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Facilitates maturation survival of T cells and activation of eosinophils. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19155487 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL7 for Human |
Record No:8
| ACCESS NO | 100950 |
| GENE | CD69 |
| DESCRIPTION | CD69 |
| NCBI ENTREZ ACCESS NO | 969 |
| UNIPROT ACCESS NO | Q07108 |
| ORGANISM | Human |
| SAMPLE | Eosinophils from Peripheral blood |
| TECHNIQUES | Western blotting Flow cytometry ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | A marker of cell activation and expressed and upregulated after IL7 induction. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19155487 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD69 for Mouse/Human |
Record No:9
| ACCESS NO | 100951 |
| GENE | AGR2 |
| DESCRIPTION | Anterior gradient 2 |
| NCBI ENTREZ ACCESS NO | 10551 |
| UNIPROT ACCESS NO | O95994 |
| ORGANISM | Human |
| SAMPLE | Trachea section |
| TECHNIQUES | immunofloresence immunoblotting RT PCR |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Involved in Mucin production in asthmatic airways. Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22403803 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Anterior Gradient 2 for Rat/Human |
Record No:10
| ACCESS NO | 100952 |
| GENE | MUC5AC |
| DESCRIPTION | Mucin 5AC |
| NCBI ENTREZ ACCESS NO | 4586 |
| UNIPROT ACCESS NO | P98088 |
| ORGANISM | Human |
| SAMPLE | Trachea section |
| TECHNIQUES | immunofloresence immunoblotting RT PCR |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Activated by Agr2 and helps in the production of mucins. Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22403803 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mucin 5AC for Mouse/Human |
Record No:11
| ACCESS NO | 100955 |
| GENE | CXCR3 |
| DESCRIPTION | Chemokine (C-X-C motif) receptor 3 |
| NCBI ENTREZ ACCESS NO | 2833 |
| UNIPROT ACCESS NO | P49682 |
| ORGANISM | Human |
| SAMPLE | Peripheral Blood mononuclear cells |
| TECHNIQUES | Flow cytometry and immunoflorescent staining |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Regulates the migration of Th1 cells into sites of Th1-driven inflammation and is a major inflammatory molecule in obese patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23760409 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | Anti-CXCR3 for Mouse/Human |
Record No:12
| ACCESS NO | 100956 |
| GENE | RETN |
| DESCRIPTION | Resistin |
| NCBI ENTREZ ACCESS NO | 56729 |
| UNIPROT ACCESS NO | Q9HD89 |
| ORGANISM | Human |
| SAMPLE | Peripheral Blood mononuclear cells |
| TECHNIQUES | Flow cytometry and immunoflorescent staining |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Synthesised mainly in mononuclear cells facilitates cellular infiltartion and increases the width of fat tissues. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23760409 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Resistin for Human |
Record No:13
| ACCESS NO | 100957 |
| GENE | IP-10 |
| DESCRIPTION | Inhibitory protein 10 |
| NCBI ENTREZ ACCESS NO | 3627 |
| UNIPROT ACCESS NO | P02778 |
| ORGANISM | Human |
| SAMPLE | Peripheral Blood mononuclear cells |
| TECHNIQUES | Flow cytometry and immunoflorescent staining |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Cause Inflammation and increased in obese patients compared to non-obese. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23760409 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IP10 for Mouse/Human |
Record No:14
| ACCESS NO | 100958 |
| GENE | MIP-1 |
| DESCRIPTION | Macrophage inflammatory proteins 1 |
| NCBI ENTREZ ACCESS NO | 6348 |
| UNIPROT ACCESS NO | P10147 |
| ORGANISM | Human |
| SAMPLE | Peripheral Blood mononuclear cells |
| TECHNIQUES | Flow cytometry and immunoflorescent staining |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Overexpressed in obese patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23760409 |
| DRUG TARGET | BE0002471 |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 1 alpha for Human |
Record No:15
| ACCESS NO | 100959 |
| GENE | CCR5 |
| DESCRIPTION | Chemokine (C-C motif) receptor 5 |
| NCBI ENTREZ ACCESS NO | 1234 |
| UNIPROT ACCESS NO | P51681 |
| ORGANISM | Human |
| SAMPLE | Peripheral Blood mononuclear cells |
| TECHNIQUES | Flow cytometry and immunoflorescent staining |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Overexpressed in obese asthma patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23760409 |
| DRUG TARGET | BE0000911 |
| MONCLONAL ANTIBODY | Anti-CCR5 for Mouse/Rat/Human |
Record No:16
| ACCESS NO | 100960 |
| GENE | ITGB3 |
| DESCRIPTION | Integrin beta 3 |
| NCBI ENTREZ ACCESS NO | 3690 |
| UNIPROT ACCESS NO | P05106 |
| ORGANISM | Human |
| SAMPLE | DNA from blood |
| TECHNIQUES | Genotyping |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Single nucleotide polymorphisms in this gene has been significantly associated with asthma in western populations |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23451109 |
| DRUG TARGET | BE0001155 |
| MONCLONAL ANTIBODY | Anti-Integrin beta 3 for Mouse/Rat/Human |
Record No:17
| ACCESS NO | 100974 |
| GENE | Ear2 (ECP) |
| DESCRIPTION | Eosinophil cationic protein |
| NCBI ENTREZ ACCESS NO | 13587 |
| UNIPROT ACCESS NO | P97425 |
| ORGANISM | Mouse |
| SAMPLE | Ear tissue |
| TECHNIQUES | ELISA and Immunohistochemistry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased expression of this protein after DBP challenge is the sign of eosinophil infiltration at the site of inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24498391 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:18
| ACCESS NO | 100975 |
| GENE | Tslp |
| DESCRIPTION | Thymic stromal lymphopoietin |
| NCBI ENTREZ ACCESS NO | 53603 |
| UNIPROT ACCESS NO | Q9JIE6 |
| ORGANISM | Mouse |
| SAMPLE | Ear tissue |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased expression of TSLP is the reason for aggravation effect of skin inflammation induced by DBP. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24498391 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TSLP for Human |
Record No:19
| ACCESS NO | 100976 |
| GENE | IFNG (IFN- gamma) |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 15978 |
| UNIPROT ACCESS NO | P01580 |
| ORGANISM | Mouse |
| SAMPLE | Ear tissue |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein level is significantly elevated after exposure to DBP combined with FITC as compared to saline challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24498391 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | N/A |
Record No:20
| ACCESS NO | 100977 |
| GENE | Il4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 16189 |
| UNIPROT ACCESS NO | P07750 |
| ORGANISM | Mouse |
| SAMPLE | Ear tissue |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein level is significantly elevated after exposure to DBP combined with FITC as compared to saline challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24498391 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:21
| ACCESS NO | 100978 |
| GENE | Il5 (IL-5) |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 16191 |
| UNIPROT ACCESS NO | P04401 |
| ORGANISM | Mouse |
| SAMPLE | Ear tissue |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein level is significantly elevated after exposure to DBP combined with FITC as compared to saline challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24498391 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:22
| ACCESS NO | 100979 |
| GENE | Il13 (IL-13) |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 16163 |
| UNIPROT ACCESS NO | P20109 |
| ORGANISM | Mouse |
| SAMPLE | Ear tissue |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein level is significantly elevated after exposure to DBP combined with FITC as compared to saline challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24498391 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:23
| ACCESS NO | 100980 |
| GENE | IL1A (IL-1A) |
| DESCRIPTION | Interleukin 1 alpha |
| NCBI ENTREZ ACCESS NO | 3552 |
| UNIPROT ACCESS NO | P01583 |
| ORGANISM | Human |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expression of this pro-inflammatory mediator is significantly increased after exposure to the respiratory sensitizers trimellitic anhydride (TMA) and ammonium hexa chloroplatinate (HClPt) at subtoxic concentrations. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL1 alpha for Human |
Record No:24
| ACCESS NO | 100981 |
| GENE | (TNF) TNF-alpha |
| DESCRIPTION | Tumor necrosis factor-alpha |
| NCBI ENTREZ ACCESS NO | 7124 |
| UNIPROT ACCESS NO | P01375 |
| ORGANISM | Human |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expression of this pro-inflammatory mediator is significantly increased after exposure to the respiratory sensitizers trimellitic anhydride (TMA) and ammonium hexa chloroplatinate (HClPt) at subtoxic concentrations. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | BE0000704 |
| MONCLONAL ANTIBODY | Anti-TNF alpha [52B83] for Mouse/Human |
Record No:25
| ACCESS NO | 100982 |
| GENE | IL10 |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 3586 |
| UNIPROT ACCESS NO | P22301 |
| ORGANISM | Human |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | Meso Scale Discovery Assays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | IL-10 production was significantly increased (3.0-fold) after exposure to both respiratory allergens TMA and HClPt. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | BE00002484 |
| MONCLONAL ANTIBODY | Anti-IL10 for Human |
Record No:26
| ACCESS NO | 100983 |
| GENE | IFNG (IFN- gamma) |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | Meso Scale Discovery Assays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This TH-1 cytokine IFN-γ is significantly induced by HClPt with up to 2810%. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | N/A |
Record No:27
| ACCESS NO | 100984 |
| GENE | IL2 |
| DESCRIPTION | Interleukin 2 |
| NCBI ENTREZ ACCESS NO | 3558 |
| UNIPROT ACCESS NO | P60568 |
| ORGANISM | Human |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | Meso Scale Discovery Assays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokine is significantly induced by HClPt. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | BE0001029 |
| MONCLONAL ANTIBODY | Anti-IL2 antibody [AP-MAB0844] for Mouse |
Record No:28
| ACCESS NO | 100985 |
| GENE | IL13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | Meso Scale Discovery Assays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This Th-2 cytokine is significantly induced by HClPt with up to 1320%. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:29
| ACCESS NO | 100986 |
| GENE | IL5 |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | Meso Scale Discovery Assays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokine is significantly induced by HClPt with up to 620%. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:30
| ACCESS NO | 100987 |
| GENE | CCL24 |
| DESCRIPTION | Eotaxin-2 |
| NCBI ENTREZ ACCESS NO | 6369 |
| UNIPROT ACCESS NO | O00175 |
| ORGANISM | Human |
| SAMPLE | Precision-cut lung slices |
| TECHNIQUES | Meso Scale Discovery Assays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokine is significantly induced by HClPt with up to 203%. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24412833 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Eotaxin 2 for Human |
Record No:31
| ACCESS NO | 100988 |
| GENE | CCL11 |
| DESCRIPTION | Eotaxin |
| NCBI ENTREZ ACCESS NO | 6356 |
| UNIPROT ACCESS NO | P51671 |
| ORGANISM | Human |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0003389 |
| MONCLONAL ANTIBODY | Anti-Eotaxin for Human |
Record No:32
| ACCESS NO | 100989 |
| GENE | CCL5 (RANTES) |
| DESCRIPTION | Chemokine (C-C motif) ligand 5 |
| NCBI ENTREZ ACCESS NO | 6352 |
| UNIPROT ACCESS NO | P13501 |
| ORGANISM | Human |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0000975 |
| MONCLONAL ANTIBODY | Anti-RANTES for Human |
Record No:33
| ACCESS NO | 100990 |
| GENE | IL5 |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:34
| ACCESS NO | 100991 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:35
| ACCESS NO | 100992 |
| GENE | CCL4 (MIP-1b) |
| DESCRIPTION | Chemokine (C-C motif) ligand 4 |
| NCBI ENTREZ ACCESS NO | 6351 |
| UNIPROT ACCESS NO | P13236 |
| ORGANISM | Human |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:36
| ACCESS NO | 100993 |
| GENE | VEGFA (VEGF) |
| DESCRIPTION | Vascular endothelial growth factor A |
| NCBI ENTREZ ACCESS NO | 7422 |
| UNIPROT ACCESS NO | P15692 |
| ORGANISM | Human |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0000163 |
| MONCLONAL ANTIBODY | Anti-VEGFA for Human |
Record No:37
| ACCESS NO | 100994 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:38
| ACCESS NO | 100995 |
| GENE | IL1B (IL-1B) |
| DESCRIPTION | Interleukin 1 beta |
| NCBI ENTREZ ACCESS NO | 3553 |
| UNIPROT ACCESS NO | P01584 |
| ORGANISM | Human |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0001051 |
| MONCLONAL ANTIBODY | Anti-IL1B for Human |
Record No:39
| ACCESS NO | 100996 |
| GENE | CCL2 (MCP-1) |
| DESCRIPTION | Chemokine (C-C motif) ligand 2 |
| NCBI ENTREZ ACCESS NO | 6347 |
| UNIPROT ACCESS NO | P13500 |
| ORGANISM | Human |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0001047 |
| MONCLONAL ANTIBODY | N/A |
Record No:40
| ACCESS NO | 100997 |
| GENE | CXCL10 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 10 |
| NCBI ENTREZ ACCESS NO | 3627 |
| UNIPROT ACCESS NO | P02778 |
| ORGANISM | Human |
| SAMPLE | Nasal lavage fluid |
| TECHNIQUES | Liquichip apparatus (Luminex) with custom designed |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an inflammatory marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24409298 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | Anti-IP10 for Human |
Record No:41
| ACCESS NO | 101055 |
| GENE | IL13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Treatment with an anti-IL13 monoclonal antibody Lebrikizumab significantly improves prebronchodilator forced expiratory volume in 1 s (FEV(1)) in a subset of subjects with uncontrolled asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24131304 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:42
| ACCESS NO | 101061 |
| GENE | CRP |
| DESCRIPTION | C-Reactive Protein |
| NCBI ENTREZ ACCESS NO | 1401 |
| UNIPROT ACCESS NO | P02741 |
| ORGANISM | Human |
| SAMPLE | Plasma |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | is one of the most characteristic surrogate markers of systemic inflammation. Significantly higher plasma CRP levels was found at acute exacerbation and remained elevated during remission compared with healthy controls. This reflects chronic systemic inflammation in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24073339 |
| DRUG TARGET | BE0000877 |
| MONCLONAL ANTIBODY | Anti-C Reactive Protein for Human |
Record No:43
| ACCESS NO | 101062 |
| GENE | MMP9 |
| DESCRIPTION | Matrix metalloproteinase - 9 |
| NCBI ENTREZ ACCESS NO | 4318 |
| UNIPROT ACCESS NO | P14780 |
| ORGANISM | Human |
| SAMPLE | Plasma |
| TECHNIQUES | ELISA and zymography |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Level of this marker was significantly higher in acute exacerbation and decreased in remission but remained significantly higher compared to healthy controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24073339 |
| DRUG TARGET | BE0000058 |
| MONCLONAL ANTIBODY | Anti-MMP9 for Rat/Human |
Record No:44
| ACCESS NO | 101063 |
| GENE | VEGFA (VEGF) |
| DESCRIPTION | Vascular endothelial growth factor A |
| NCBI ENTREZ ACCESS NO | 7422 |
| UNIPROT ACCESS NO | P15692 |
| ORGANISM | Human |
| SAMPLE | Saliva |
| TECHNIQUES | Fiber-optic bundles and antibody-based microarrays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This saliva biomarker was found to be upregulated significantly in asthma patients as compared to control. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23972398 |
| DRUG TARGET | BE0000163 |
| MONCLONAL ANTIBODY | Anti-VEGFA for Human |
Record No:45
| ACCESS NO | 101064 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Interleukin 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| SAMPLE | Saliva |
| TECHNIQUES | Fiber-optic bundles and antibody-based microarrays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This saliva biomarker was found to be upregulated significantly in asthma patients as compared to control. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23972398 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:46
| ACCESS NO | 101065 |
| GENE | EGF |
| DESCRIPTION | Epidermal growth factor |
| NCBI ENTREZ ACCESS NO | 1950 |
| UNIPROT ACCESS NO | P01133 |
| ORGANISM | Human |
| SAMPLE | Saliva |
| TECHNIQUES | Fiber-optic bundles and antibody-based microarrays |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This saliva biomarker was found to be upregulated significantly in asthma patients as compared to control. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23972398 |
| DRUG TARGET | BE0000953 |
| MONCLONAL ANTIBODY | N/A |
Record No:47
| ACCESS NO | 101066 |
| GENE | IGHE (IgE) |
| DESCRIPTION | Immunoglobulin E |
| NCBI ENTREZ ACCESS NO | 3497 |
| UNIPROT ACCESS NO | P01854 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IgE [XTE4] for Human |
Record No:48
| ACCESS NO | 101067 |
| GENE | CRP |
| DESCRIPTION | C-Reactive Protein |
| NCBI ENTREZ ACCESS NO | 1401 |
| UNIPROT ACCESS NO | P02741 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | BE0000877 |
| MONCLONAL ANTIBODY | Anti-C Reactive Protein for Human |
Record No:49
| ACCESS NO | 101068 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:50
| ACCESS NO | 101069 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Interleukin 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:51
| ACCESS NO | 101070 |
| GENE | IL17A (IL17) |
| DESCRIPTION | Interleukin 17A |
| NCBI ENTREZ ACCESS NO | 3605 |
| UNIPROT ACCESS NO | Q16552 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:52
| ACCESS NO | 101071 |
| GENE | (TNF) TNF- alpha |
| DESCRIPTION | Tumor necrosis factor-alpha |
| NCBI ENTREZ ACCESS NO | 7124 |
| UNIPROT ACCESS NO | P01375 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | BE0000704 |
| MONCLONAL ANTIBODY | Anti-TNF alpha [52B83] for Mouse/Human |
Record No:53
| ACCESS NO | 101072 |
| GENE | RNASE3 (ECP) |
| DESCRIPTION | Eosinophil cationic protein |
| NCBI ENTREZ ACCESS NO | 6037 |
| UNIPROT ACCESS NO | P12724 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | BE0000908 |
| MONCLONAL ANTIBODY | N/A |
Record No:54
| ACCESS NO | 101073 |
| GENE | MMP25 |
| DESCRIPTION | Leukolysin |
| NCBI ENTREZ ACCESS NO | 64386 |
| UNIPROT ACCESS NO | Q9NPA2 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | BE0003700 |
| MONCLONAL ANTIBODY | Anti-MMP25 for Human |
Record No:55
| ACCESS NO | 101074 |
| GENE | CHI3L1 (YKL-40) |
| DESCRIPTION | Chitinase 3-like 1 |
| NCBI ENTREZ ACCESS NO | 1116 |
| UNIPROT ACCESS NO | P36222 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:56
| ACCESS NO | 101075 |
| GENE | CD86 |
| DESCRIPTION | soluble CD86 |
| NCBI ENTREZ ACCESS NO | 942 |
| UNIPROT ACCESS NO | P42081 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | In silico Pubmed database seraching and analysis |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This serum biomarker is capable of supporting a diagnosis of asthma in order to counter mistreatment and misdiagnosis with other obstructive airways disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23952480 |
| DRUG TARGET | BE0000846 |
| MONCLONAL ANTIBODY | Anti-CD86 [EP1158Y] for Rat/Human |
Record No:57
| ACCESS NO | 101076 |
| GENE | POSTN |
| DESCRIPTION | Periostin |
| NCBI ENTREZ ACCESS NO | 10631 |
| UNIPROT ACCESS NO | Q15063 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is a candidate for the predictive marker of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23943655 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Periostin for Human |
Record No:58
| ACCESS NO | 101077 |
| GENE | EPX |
| DESCRIPTION | Eosinophil peroxidase |
| NCBI ENTREZ ACCESS NO | 8288 |
| UNIPROT ACCESS NO | P11678 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Poorly controlled asthma is associated with higher sputum EPX and chronic residential traffic pollution exposure may be associated with eosinophilic but not neutrophilic inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23931679 |
| DRUG TARGET | BE0000355 |
| MONCLONAL ANTIBODY | Anti-EPX for Human |
Record No:59
| ACCESS NO | 101081 |
| GENE | RNASE2 |
| DESCRIPTION | Eosinophil-derived neurotoxin |
| NCBI ENTREZ ACCESS NO | 6036 |
| UNIPROT ACCESS NO | P10153 |
| ORGANISM | Human |
| SAMPLE | Plasma |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein is present in higher levels in subjects with aspirin exacerbated respiratory disease (AERD) as compared with aspirin tolerant asthma (ATA )subjects. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23805255 |
| DRUG TARGET | BE0001306 |
| MONCLONAL ANTIBODY | N/A |
Record No:60
| ACCESS NO | 101082 |
| GENE | LCN2 (NGAL) |
| DESCRIPTION | Gelatinase-associated lipocalin |
| NCBI ENTREZ ACCESS NO | 3934 |
| UNIPROT ACCESS NO | P80188 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Only sputum NGAL is significantly elevated in COPD-asthma overlap compared with COPD (p=0.00016) and could be used to differentiate patients with overlap from those with COPD. Increased induced sputum levels of NGAL is a characteristic feature of overlap suggesting enhanced neutrophilic airway inflammation and/or airway epithelial injury in COPD-asthma overlap. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23794464 |
| DRUG TARGET | BE0001084 |
| MONCLONAL ANTIBODY | Anti-Lipocalin 2 for Human |
Record No:61
| ACCESS NO | 101083 |
| GENE | POSTN |
| DESCRIPTION | Periostin |
| NCBI ENTREZ ACCESS NO | 10631 |
| UNIPROT ACCESS NO | Q15063 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Serum periostin appears to be a useful biomarker for the development of airflow limitation in asthmatic patients on inhaled corticosteroids. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23791506 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Periostin for Human |
Record No:62
| ACCESS NO | 101084 |
| GENE | EDN1 (ET-1) |
| DESCRIPTION | Endothelin-1 |
| NCBI ENTREZ ACCESS NO | 494214 |
| UNIPROT ACCESS NO | Q5NRQ1 |
| ORGANISM | Cat |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid |
| TECHNIQUES | Endothelin enzyme immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | BAL ET-1 concentration can be used to differentiate normal from those with experimentally induced asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23750948 |
| DRUG TARGET | BE0003384 |
| MONCLONAL ANTIBODY | Anti-Endothelin 1 [TR.ET.48.5] for Mouse/Rat/Human |
Record No:63
| ACCESS NO | 101085 |
| GENE | Igha (IgA) |
| DESCRIPTION | Immunoglobulin alpha |
| NCBI ENTREZ ACCESS NO | 238447 |
| UNIPROT ACCESS NO | |
| ORGANISM | Mouse |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein is highly expressed after allergen sensitization in prebiotic-fed mice. It is related to tolerance and would play a crucial role in the prevention of allergy. Perinatal and postweaning exposure to prebiotics is very encouraging because it allows the induction of several tolerance-related biomarkers |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IgA a for Human |
Record No:64
| ACCESS NO | 101086 |
| GENE | Ighv1-9 (IgG2a) |
| DESCRIPTION | Immunoglobulin G2A |
| NCBI ENTREZ ACCESS NO | 668478 |
| UNIPROT ACCESS NO | |
| ORGANISM | Mouse |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein is highly expressed after allergen sensitization in prebiotic-fed mice. It is related to tolerance and would play a crucial role in the prevention of allergy. Perinatal and postweaning exposure to prebiotics is very encouraging because it allows the induction of several tolerance-related biomarkers |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:65
| ACCESS NO | 101087 |
| GENE | Il10 (IL-10) |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 16153 |
| UNIPROT ACCESS NO | P18893 |
| ORGANISM | Mouse |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein is highly expressed after allergen sensitization in prebiotic-fed mice. It is related to tolerance and would play a crucial role in the prevention of allergy. Perinatal and postweaning exposure to prebiotics is very encouraging because it allows the induction of several tolerance-related biomarkers |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | N/A |
Record No:66
| ACCESS NO | 101088 |
| GENE | Tgfb (TGF- beta) |
| DESCRIPTION | TGF beta binding protein |
| NCBI ENTREZ ACCESS NO | 268977 |
| UNIPROT ACCESS NO | Q8CG19 |
| ORGANISM | Mouse |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein is highly expressed after allergen sensitization in prebiotic-fed mice. It is related to tolerance and would play a crucial role in the prevention of allergy. Perinatal and postweaning exposure to prebiotics is very encouraging because it allows the induction of several tolerance-related biomarkers |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | BE0003782 |
| MONCLONAL ANTIBODY | Anti-TGFBI [EPR12078(B)] for Human/Mouse/Rat |
Record No:67
| ACCESS NO | 101089 |
| GENE | IFNG (IFN- gamma) |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 15978 |
| UNIPROT ACCESS NO | P01580 |
| ORGANISM | Mouse |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein is highly expressed after allergen sensitization in prebiotic-fed mice. It is related to tolerance and would play a crucial role in the prevention of allergy. Perinatal and postweaning exposure to prebiotics is very encouraging because it allows the induction of several tolerance-related biomarkers |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | N/A |
Record No:68
| ACCESS NO | 101090 |
| GENE | Il4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 16189 |
| UNIPROT ACCESS NO | P07750 |
| ORGANISM | Mouse |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is a biomarker related to allergy and is not affected anyway by allergen challenge followed by prebiotic injestion due to expression of tolerance related biomarkers. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:69
| ACCESS NO | 101091 |
| GENE | Il17a (IL-17a) |
| DESCRIPTION | Interleukin-17a |
| NCBI ENTREZ ACCESS NO | 16171 |
| UNIPROT ACCESS NO | Q62386 |
| ORGANISM | Mouse |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is a biomarker related to allergy and is not affected anyway by allergen challenge followed by prebiotic injestion due to expression of tolerance related biomarkers. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:70
| ACCESS NO | 101092 |
| GENE | Fcer1g (CD23) |
| DESCRIPTION | CD23 molecule |
| NCBI ENTREZ ACCESS NO | 14127 |
| UNIPROT ACCESS NO | P20491 |
| ORGANISM | Mouse |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is a biomarker related to allergy and is not affected anyway by allergen challenge followed by prebiotic injestion due to expression of tolerance related biomarkers. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | BE0000049 |
| MONCLONAL ANTIBODY | N/A |
Record No:71
| ACCESS NO | 101093 |
| GENE | Ighe (IgE) |
| DESCRIPTION | Immunoglobulin E |
| NCBI ENTREZ ACCESS NO | 380792 |
| UNIPROT ACCESS NO | P06336 |
| ORGANISM | Mouse |
| SAMPLE | Supernatent of spleen cell cultures |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is a biomarker related to allergy and is not affected anyway by allergen challenge followed by prebiotic injestion due to expression of tolerance related biomarkers. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23746232 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IgE [XTE4] for Human |
Record No:72
| ACCESS NO | 101094 |
| GENE | CHI3L1 (YKL-40) |
| DESCRIPTION | Chitinase 3-like 1 |
| NCBI ENTREZ ACCESS NO | 1116 |
| UNIPROT ACCESS NO | P36222 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | ELISA and SNP typing of the gene promoter |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | YKL-40 levels are increased in children with severe and therapy-resistant asthma compared to healthy children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23628340 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:73
| ACCESS NO | 101095 |
| GENE | ICAM1 (sICAM-1) |
| DESCRIPTION | Intercellular adhesion molecule 1 |
| NCBI ENTREZ ACCESS NO | 3383 |
| UNIPROT ACCESS NO | P0536 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Patients with shortness in breath can be treated effectively with fluticasone effectively. The effectiveness of treatment can be monitered by significant changes in this biomarker level in serum. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23606983 |
| DRUG TARGET | BE0001085 |
| MONCLONAL ANTIBODY | Anti-ICAM1 for Rat/Human |
Record No:74
| ACCESS NO | 101096 |
| GENE | RNASE3 (ECP) |
| DESCRIPTION | Eosinophil cationic protei |
| NCBI ENTREZ ACCESS NO | 6037 |
| UNIPROT ACCESS NO | P12724 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This protein together with peripheral eosinophil leve is found to be sensitive markers for asthma severity. Patients with shortness in breath can be treated effectively with fluticasone effectively. The effectiveness of treatment can be monitered by significant changes in this biomarker level in serum. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23606983 |
| DRUG TARGET | BE0000908 |
| MONCLONAL ANTIBODY | N/A |
Record No:75
| ACCESS NO | 101097 |
| GENE | CXCL10 (IP-10) |
| DESCRIPTION | Inducible protein-10 |
| NCBI ENTREZ ACCESS NO | 3627 |
| UNIPROT ACCESS NO | P02778 |
| ORGANISM | Human |
| SAMPLE | Exhaled breath condensate |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is a biomarker of exacerbation. This chemokine is strongly associated with viral infection in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23521049 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | N/A |
Record No:76
| ACCESS NO | 101098 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is an indicator of exacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23521049 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:77
| ACCESS NO | 101099 |
| GENE | MED24 |
| DESCRIPTION | Mediator complex subunit 24 |
| NCBI ENTREZ ACCESS NO | 9862 |
| UNIPROT ACCESS NO | O75448 |
| ORGANISM | Human |
| SAMPLE | gDNA |
| TECHNIQUES | SNP typing |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | SNP related alleles of this gene in combination with deregulated phosphatidylcholines in asthmatics may serve as biomarker of this disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23452035 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:78
| ACCESS NO | 101100 |
| GENE | PSMD3 |
| DESCRIPTION | Proteasome 26S subunit |
| NCBI ENTREZ ACCESS NO | 5709 |
| UNIPROT ACCESS NO | O43242 |
| ORGANISM | Human |
| SAMPLE | gDNA |
| TECHNIQUES | SNP typing |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | SNP related alleles of this gene in combination with deregulated phosphatidylcholines in asthmatics may serve as biomarker of this disease. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23452035 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:79
| ACCESS NO | 101124 |
| GENE | RETN |
| DESCRIPTION | Resistin |
| NCBI ENTREZ ACCESS NO | 56729 |
| UNIPROT ACCESS NO | Q9HD89 |
| ORGANISM | Human |
| SAMPLE | Fasting blood |
| TECHNIQUES | Multiplex immunoassay using Luminex 100 system pla |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Exposure to polycyclic hydrocarbon has strong association with increase in serum concentration of this biomarker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23286340 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Resistin for Human |
Record No:80
| ACCESS NO | 101125 |
| GENE | IFNG (IFN- gamma) |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| SAMPLE | Fasting blood |
| TECHNIQUES | Multiplex immunoassay using Luminex 100 system pla |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Exposure to polycyclic hydrocarbon has strong association with decrease in serum concentration of this biomarker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23286340 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | N/A |
Record No:81
| ACCESS NO | 101126 |
| GENE | IL5 |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| SAMPLE | Fasting blood |
| TECHNIQUES | Multiplex immunoassay using Luminex 100 system pla |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Exposure to polycyclic hydrocarbon has strong association with decrease in serum concentration of this biomarker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23286340 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:82
| ACCESS NO | 101127 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| SAMPLE | Fasting blood |
| TECHNIQUES | Multiplex immunoassay using Luminex 100 system pla |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Exposure to polycyclic hydrocarbon has strong association with decrease in serum concentration of this biomarker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23286340 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:83
| ACCESS NO | 101128 |
| GENE | IL10 |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 3586 |
| UNIPROT ACCESS NO | P22301 |
| ORGANISM | Human |
| SAMPLE | Fasting blood |
| TECHNIQUES | Multiplex immunoassay using Luminex 100 system pla |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Exposure to polycyclic hydrocarbon has strong association with decrease in serum concentration of this biomarker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23286340 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | Anti-IL10 for Human |
Record No:84
| ACCESS NO | 101129 |
| GENE | IL4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| SAMPLE | Fasting blood |
| TECHNIQUES | Multiplex immunoassay using Luminex 100 system pla |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Exposure to polycyclic hydrocarbon has strong association with increase in serum concentration of this biomarker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23286340 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:85
| ACCESS NO | 101132 |
| GENE | Tacr1 (NK1-R) |
| DESCRIPTION | Tachykinin substance P |
| NCBI ENTREZ ACCESS NO | 21336 |
| UNIPROT ACCESS NO | P30548 |
| ORGANISM | Mouse |
| SAMPLE | Serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | NK1-R blockade improved obesity related biomarkers and as well as allergen sensitization and bronchial inflammation. These positive effects support a common pathway in the obese-asthma phenotype and highlight SP as a target with potential clinical interest in the obese-asthma epidemics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23176443 |
| DRUG TARGET | BE0000384 |
| MONCLONAL ANTIBODY | N/A |
Record No:86
| ACCESS NO | 101133 |
| GENE | CCL22 |
| DESCRIPTION | Chemokine (C-C motif) ligand 22 |
| NCBI ENTREZ ACCESS NO | 6367 |
| UNIPROT ACCESS NO | O00626 |
| ORGANISM | Human |
| SAMPLE | Cord blood |
| TECHNIQUES | Multiplexed Luminex assay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | High cord blood levels of the Th2 related chemokine CCL22 were significantly associated with high total- IgE levels during the first 6 years of life. This suggests an inborn Th2 skewing of the immune system in healthy newborns developing elevated total-IgE later in life. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23106659 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:87
| ACCESS NO | 101137 |
| GENE | POSTN |
| DESCRIPTION | Periostin |
| NCBI ENTREZ ACCESS NO | 10631 |
| UNIPROT ACCESS NO | Q15063 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Periostin is a systemic biomarker of airway eosinophilia in asthmatic patients and has potential utility in patient selection for emerging asthma therapeutics targeting TH2 inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22857879 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Periostin for Human |
Record No:88
| ACCESS NO | 101138 |
| GENE | NOS2 |
| DESCRIPTION | Inducible nitric oxide synthase 2 |
| NCBI ENTREZ ACCESS NO | 4843 |
| UNIPROT ACCESS NO | P35228 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Bronchial epithelial expression levels of this gene correlated with bronchial IL-13 and IL-5 expression. We observed relatively strong positive correlations between bronchial or systemic eosinophilia and serum periostin levels. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22857879 |
| DRUG TARGET | BE0000005 |
| MONCLONAL ANTIBODY | Anti-iNOS for Mouse/Human |
Record No:89
| ACCESS NO | 101139 |
| GENE | VEGFA (VEGF) |
| DESCRIPTION | Vascular endothelial growth factor A |
| NCBI ENTREZ ACCESS NO | 7422 |
| UNIPROT ACCESS NO | P15692 |
| ORGANISM | Human |
| SAMPLE | Mast cell |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | VEGF dictates angiogenesis in part by induction of myeloid progenitor cell mobilization into the circulation and subsequent recruitment to local vascular bed. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22837863 |
| DRUG TARGET | BE0000163 |
| MONCLONAL ANTIBODY | N/A |
Record No:90
| ACCESS NO | 101140 |
| GENE | IL4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| SAMPLE | Extracts of lung tissue |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This inflammatory marker is upregulated upon DHAP exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22701742 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:91
| ACCESS NO | 101141 |
| GENE | IFNG (IFN-γ) |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| SAMPLE | Extracts of lung tissue |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This inflammatory marker is upregulated upon DHAP exposure. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22701742 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | N/A |
Record No:92
| ACCESS NO | 101144 |
| GENE | CCL2 (MCP-1) |
| DESCRIPTION | Monocyte chemoattractant protein-1 |
| NCBI ENTREZ ACCESS NO | 6347 |
| UNIPROT ACCESS NO | P13500 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Higher levels of this biomarker is associated with male sex. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0001047 |
| MONCLONAL ANTIBODY | N/A |
Record No:93
| ACCESS NO | 101145 |
| GENE | VEGFA (VEGF) |
| DESCRIPTION | Vascular endothelial growth factor A |
| NCBI ENTREZ ACCESS NO | 7422 |
| UNIPROT ACCESS NO | P15692 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Higher levels of this biomarker is associated with male sex. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0000163 |
| MONCLONAL ANTIBODY | Anti-VEGFA for Human |
Record No:94
| ACCESS NO | 101146 |
| GENE | IL1B (IL-1B) |
| DESCRIPTION | Interleukin 1 beta |
| NCBI ENTREZ ACCESS NO | 3553 |
| UNIPROT ACCESS NO | P01584 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Higher levels of this biomarker is associated with male sex. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0001051 |
| MONCLONAL ANTIBODY | Anti-IL1B for Human |
Record No:95
| ACCESS NO | 101147 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokoine is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:96
| ACCESS NO | 101148 |
| GENE | IL10 |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 3586 |
| UNIPROT ACCESS NO | P22301 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokoine is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | Anti-IL10 for Mouse |
Record No:97
| ACCESS NO | 101149 |
| GENE | CSF3 (G-CSF) |
| DESCRIPTION | Granulocyte macrophage colony-stimulating factor |
| NCBI ENTREZ ACCESS NO | 1440 |
| UNIPROT ACCESS NO | P09919 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This gene is involved in neovascularization/remodulation after tissue damage. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0000793 |
| MONCLONAL ANTIBODY | Anti-G-CSF for Human |
Record No:98
| ACCESS NO | 101150 |
| GENE | IL7 |
| DESCRIPTION | Interleukin 7 |
| NCBI ENTREZ ACCESS NO | 3574 |
| UNIPROT ACCESS NO | P13232 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokoine is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:99
| ACCESS NO | 101151 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | strong chemotactic effect on neutrophils |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:100
| ACCESS NO | 101152 |
| GENE | IL17A (IL17) |
| DESCRIPTION | Interleukin 17A |
| NCBI ENTREZ ACCESS NO | 3605 |
| UNIPROT ACCESS NO | Q16552 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokoine is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:101
| ACCESS NO | 101153 |
| GENE | IL13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This cytokoine is involved in adaptive immunity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:102
| ACCESS NO | 101154 |
| GENE | CCL3 (MIP-1α) |
| DESCRIPTION | Macrophage inflammatory protein-1 alpha |
| NCBI ENTREZ ACCESS NO | 6348 |
| UNIPROT ACCESS NO | P10147 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This gene is involved in innate immune response. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0002471 |
| MONCLONAL ANTIBODY | N/A |
Record No:103
| ACCESS NO | 101155 |
| GENE | PDGF-bb |
| DESCRIPTION | Platelet-derived growth factor beta polypeptide homodimer |
| NCBI ENTREZ ACCESS NO | 5155 |
| UNIPROT ACCESS NO | P01127 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This gene is involved in neovascularization/remodulation after tissue damage. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:104
| ACCESS NO | 101156 |
| GENE | CCL11 |
| DESCRIPTION | Eotaxin |
| NCBI ENTREZ ACCESS NO | 6356 |
| UNIPROT ACCESS NO | P51671 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This gene is involved in neovascularization/remodulation after tissue damage. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0003389 |
| MONCLONAL ANTIBODY | Anti-Eotaxin for Human |
Record No:105
| ACCESS NO | 101157 |
| GENE | FGF2 (FGF-b) |
| DESCRIPTION | Fibroblast growth factor 2 (basic) |
| NCBI ENTREZ ACCESS NO | 2247 |
| UNIPROT ACCESS NO | P09038 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This gene is involved in neovascularization/remodulation after tissue damage. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0001015 |
| MONCLONAL ANTIBODY | Anti-FGF2 for Human |
Record No:106
| ACCESS NO | 101158 |
| GENE | CCL5 (RANTES) |
| DESCRIPTION | Chemokine (C-C motif) ligand 5 |
| NCBI ENTREZ ACCESS NO | 6352 |
| UNIPROT ACCESS NO | P13501 |
| ORGANISM | Human |
| SAMPLE | Nasopharyngeal aspirates (NPA) |
| TECHNIQUES | Multiplex immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This gene is involved in neovascularization/remodulation after tissue damage. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22554061 |
| DRUG TARGET | BE0000975 |
| MONCLONAL ANTIBODY | Anti-RANTES for Human |
Record No:107
| ACCESS NO | 101178 |
| GENE | Rela |
| DESCRIPTION | p65 subunit of NF kappa beta |
| NCBI ENTREZ ACCESS NO | 19697 |
| UNIPROT ACCESS NO | Q04207 |
| ORGANISM | Mouse |
| SAMPLE | Nuclear extracts from lung tissues |
| TECHNIQUES | Immunoflorescence |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Fisetin repressed TNF alpha induced NF kappa B dependent reporter gene expression. This findings implicate a potential therapeutic value of fisetin in the treatment of asthma through negative regulation of NF kappa beta pathway. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22290391 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:108
| ACCESS NO | 101179 |
| GENE | Il4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 16189 |
| UNIPROT ACCESS NO | P07750 |
| ORGANISM | Mouse |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Fisetin dose-dependently inhibited ovalbumin-induced increases in this marker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22290391 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:109
| ACCESS NO | 101180 |
| GENE | Il5 (IL-5) |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 16191 |
| UNIPROT ACCESS NO | P04401 |
| ORGANISM | Mouse |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Fisetin dose-dependently inhibited ovalbumin-induced increases in this marker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22290391 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:110
| ACCESS NO | 101181 |
| GENE | Il13 (IL-13) |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 16163 |
| UNIPROT ACCESS NO | P20109 |
| ORGANISM | Mouse |
| SAMPLE | Broncho Alveolar Lavage (BAL)F |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Fisetin dose-dependently inhibited ovalbumin-induced increases in this marker. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22290391 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:111
| ACCESS NO | 101191 |
| GENE | IL13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| SAMPLE | Broncho Alveolar Lavage (BAL) fluid |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | TGF beta activation was also greater in children with severe asthma and was associated with higher IL-13 concentrations. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22206775 |
| DRUG TARGET | BE0000984 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:112
| ACCESS NO | 101192 |
| GENE | ADIPOQ |
| DESCRIPTION | adiponectin |
| NCBI ENTREZ ACCESS NO | 9370 |
| UNIPROT ACCESS NO | Q15848 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | The adipocytes are the most important source of adiponectin ans its serum levels are markedly decreased in individuals with visceral obesity. Interdisciplinary therapy resulted in increase from 4 to 5.1. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22170805 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Adiponectin [19F1] for Mouse/Rat/Human |
Record No:113
| ACCESS NO | 101193 |
| GENE | CRP |
| DESCRIPTION | C-Reactive Protein |
| NCBI ENTREZ ACCESS NO | 1401 |
| UNIPROT ACCESS NO | P02741 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | The higher CRP levels was correlated with severe asthma. CRP concentrations reduced after 1 year of interdisciplinary treatment from 2073 to 1. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22170805 |
| DRUG TARGET | BEE0000877 |
| MONCLONAL ANTIBODY | Anti-C Reactive Protein for Human |
Record No:114
| ACCESS NO | 101194 |
| GENE | LEP |
| DESCRIPTION | leptin |
| NCBI ENTREZ ACCESS NO | 3952 |
| UNIPROT ACCESS NO | P41159 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | The higher leptin levels was correlated with severe asthma. CRP concentrations reduced after 1 year of interdisciplinary treatment from 59 to 33. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22170805 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:115
| ACCESS NO | 101227 |
| GENE | C3 |
| DESCRIPTION | Complement component C3 |
| NCBI ENTREZ ACCESS NO | 718 |
| UNIPROT ACCESS NO | P01024 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | Immunodiffusion assay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increase in the serum levels of the C3 components of the complement system in the majority of the patients with intermittent atopic asthma was observed. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22065014 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:116
| ACCESS NO | 101228 |
| GENE | C4 |
| DESCRIPTION | Complement component C4 |
| NCBI ENTREZ ACCESS NO | 720 |
| UNIPROT ACCESS NO | P0C0L4 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | Immunodiffusion assay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increase in the serum levels of the C4 components of the complement system in the majority of the patients with intermittent atopic asthma was observed. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 22065014 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:117
| ACCESS NO | 101233 |
| GENE | (TNF) TNF- alpha |
| DESCRIPTION | Tumor necrosis factor-alpha |
| NCBI ENTREZ ACCESS NO | 7124 |
| UNIPROT ACCESS NO | P01375 |
| ORGANISM | Human |
| SAMPLE | Fasting serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This is a Th1 specific biomarker can distinguish obesity asthma from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21980061 |
| DRUG TARGET | BE0000704 |
| MONCLONAL ANTIBODY | Anti-TNF alpha [52B83] for Mouse/Human |
Record No:118
| ACCESS NO | 101234 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| SAMPLE | Fasting serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This is a Th1 specific biomarker can distinguish obesity asthma from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21980061 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:119
| ACCESS NO | 101235 |
| GENE | IFNG (IFN-γ) |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| SAMPLE | Fasting serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This is a Th1 specific biomarker can distinguish obesity asthma from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21980061 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | N/A |
Record No:120
| ACCESS NO | 101236 |
| GENE | CXCL10 (IP-10) |
| DESCRIPTION | Inducible protein-10 |
| NCBI ENTREZ ACCESS NO | 3627 |
| UNIPROT ACCESS NO | P02778 |
| ORGANISM | Human |
| SAMPLE | Fasting serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This is a Th1 specific biomarker can distinguish obesity asthma from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21980061 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | N/A |
Record No:121
| ACCESS NO | 101237 |
| GENE | IL4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| SAMPLE | Fasting serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This is a Th2 specific biomarker can distinguish obesity asthma from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21980061 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:122
| ACCESS NO | 101238 |
| GENE | IL5 |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| SAMPLE | Fasting serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This is a Th2 specific biomarker can distinguish obesity asthma from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21980061 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:123
| ACCESS NO | 101239 |
| GENE | IL13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| SAMPLE | Fasting serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This is a Th2 specific biomarker can distinguish obesity asthma from atopic asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21980061 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:124
| ACCESS NO | 101240 |
| GENE | CCL16 |
| DESCRIPTION | Chemokine (C-C motif) ligand 16 |
| NCBI ENTREZ ACCESS NO | 6360 |
| UNIPROT ACCESS NO | O15467 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Small changes in serum CCL16 level reveal the existence of early subclinical effects in the airways epithelium and it is most likely caused by irritating agents in wood smoke. A decrease of CC16 and an increase of the CC16 over SPD ratio in serum can be explained by a decreased production of CC16. CCL16 is a major protein in the lung with anti-inflammatory activity and the increased lung permeability. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21901861 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-LEC for Human |
Record No:125
| ACCESS NO | 101241 |
| GENE | CHI3L1 (YKL-40) |
| DESCRIPTION | Chitinase 3-like 1 |
| NCBI ENTREZ ACCESS NO | 1116 |
| UNIPROT ACCESS NO | P36222 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | YKL-40 seems to be a good marker of asthma.But its level may not correlate with clinical outcome. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21899483 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:126
| ACCESS NO | 101242 |
| GENE | IGHE (IgE) |
| DESCRIPTION | Immunoglobulin E |
| NCBI ENTREZ ACCESS NO | 3497 |
| UNIPROT ACCESS NO | P01854 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | Aptamer-based biosensor (apta-biosensor) using CNT |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | In this study the described aptamer-based CNT-FET device enable the production of label-free ultrasensitive electronic biosensors to detect IgE in allergic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21780424 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IgE [XTE4] for Human |
Record No:127
| ACCESS NO | 101244 |
| GENE | Il4 (IL-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 16189 |
| UNIPROT ACCESS NO | P07750 |
| ORGANISM | Mouse |
| SAMPLE | Lymphocyte |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Artesunate significantly reduces the level of this Th2 specific inflammatory cytokine induced after ovalbumin challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:128
| ACCESS NO | 101245 |
| GENE | Il5 (IL-5) |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 16191 |
| UNIPROT ACCESS NO | P04401 |
| ORGANISM | Mouse |
| SAMPLE | Lymphocyte |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Artesunate significantly reduces the level of this Th2 specific inflammatory cytokine induced after ovalbumin challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Human |
Record No:129
| ACCESS NO | 101246 |
| GENE | Il13 (IL-13) |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 16163 |
| UNIPROT ACCESS NO | P20109 |
| ORGANISM | Mouse |
| SAMPLE | Lymphocyte |
| TECHNIQUES | Immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Artesunate significantly reduces the level of this Th2 specific inflammatory cytokine induced after ovalbumin challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:130
| ACCESS NO | 101258 |
| GENE | Akt1 (Akt) |
| DESCRIPTION | Thymoma viral proto-oncogene 1 |
| NCBI ENTREZ ACCESS NO | 11651 |
| UNIPROT ACCESS NO | P31750 |
| ORGANISM | Mouse |
| SAMPLE | Lung tissue |
| TECHNIQUES | Immunoblot |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Artesunate markedly inhibited the EGF-induced phosphorylation of Akt. Thus EGF induced activation of inflammatory PI3K/Akt signaling pathway is suppressed. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-AKT1 for Mouse/Human |
Record No:131
| ACCESS NO | 101259 |
| GENE | Tsc2 |
| DESCRIPTION | Tuberin |
| NCBI ENTREZ ACCESS NO | 22084 |
| UNIPROT ACCESS NO | Q61037 |
| ORGANISM | Mouse |
| SAMPLE | Lung tissue |
| TECHNIQUES | Immunoblot |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Artesunate markedly inhibited the EGF-induced phosphorylation of Akt. Thus EGF induced activation of inflammatory PI3K/Akt signaling pathway is suppressed. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:132
| ACCESS NO | 101260 |
| GENE | Rps6kb1 (p70S6K) |
| DESCRIPTION | Polypeptide 1 of ribosomal protein S6 kinase |
| NCBI ENTREZ ACCESS NO | 72508 |
| UNIPROT ACCESS NO | Q8BSK8 |
| ORGANISM | Mouse |
| SAMPLE | Lung tissue |
| TECHNIQUES | Immunoblot |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Artesunate markedly inhibited the EGF-induced phosphorylation of Akt. Thus EGF induced activation of inflammatory PI3K/Akt signaling pathway is suppressed. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | BE0001193 |
| MONCLONAL ANTIBODY | N/A |
Record No:133
| ACCESS NO | 101261 |
| GENE | Eif4ebp1 (4E-BP1) |
| DESCRIPTION | Eukaryotic translation initiation factor 4E binding protein 1 |
| NCBI ENTREZ ACCESS NO | 13685 |
| UNIPROT ACCESS NO | Q60876 |
| ORGANISM | Mouse |
| SAMPLE | Lung tissue |
| TECHNIQUES | Immunoblot |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Artesunate markedly inhibited the EGF-induced phosphorylation of Akt. Thus EGF induced activation of inflammatory PI3K/Akt signaling pathway is suppressed. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:134
| ACCESS NO | 101262 |
| GENE | Rela (NF-kB) |
| DESCRIPTION | p65 subunit of NF kappa beta |
| NCBI ENTREZ ACCESS NO | 19697 |
| UNIPROT ACCESS NO | Q04207 |
| ORGANISM | Mouse |
| SAMPLE | Nuclear extracts from lung tissues |
| TECHNIQUES | TransAM NF-kB transcription factor assay kit |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | EGF induced activation of PI3K/Akt signaling pathway causes down stream increase in NF-kB DNA binding activity. Artesunate has been found to decrease the transactivation of this transcription factor. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21695271 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:135
| ACCESS NO | 101263 |
| GENE | EPX |
| DESCRIPTION | Eosinophil protein X |
| NCBI ENTREZ ACCESS NO | 8288 |
| UNIPROT ACCESS NO | P11678 |
| ORGANISM | Human |
| SAMPLE | Urine |
| TECHNIQUES | Double-antibody immunoassay |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Eosinophil protein X in urine from asymptomatic neonates is a biomarker significantly associated with later development of allergic sensitization. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21680952 |
| DRUG TARGET | BE0000355 |
| MONCLONAL ANTIBODY | Anti-EPX for Human |
Record No:136
| ACCESS NO | 101264 |
| GENE | IL6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This study suggests that there is not any difference between severe and mild asthma in serum IL-8 and IL-6. Thus level of serum cytokines may not predict severity of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24024021 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | Anti-IL6 for Rat/Human |
Record No:137
| ACCESS NO | 101265 |
| GENE | CXCL8 (IL8) |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | This study suggests that there is not any difference between severe and mild asthma in serum IL-8 and IL-6. Thus level of serum cytokines may not predict severity of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24024021 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human |
Record No:138
| ACCESS NO | 101266 |
| GENE | IGHE (IgE) |
| DESCRIPTION | Immunoglobulin E |
| NCBI ENTREZ ACCESS NO | 3497 |
| UNIPROT ACCESS NO | P01854 |
| ORGANISM | Human |
| SAMPLE | Cord blood |
| TECHNIQUES | Pharmacia UniCAP system |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | An elevated cord blood IgE level modestly correlates with elevated total IgE and is associated with a slightly higher likelihood of allergic sensitization among young adults. However cord IgE is not a strong predictor of clinical allergic disorders in this age group. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21354027 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IgE [XTE4] for Human |
Record No:139
| ACCESS NO | 101267 |
| GENE | ADIPOQ |
| DESCRIPTION | adiponectin |
| NCBI ENTREZ ACCESS NO | 9370 |
| UNIPROT ACCESS NO | Q15848 |
| ORGANISM | Human |
| SAMPLE | Broncho Alveolar Lavage (BAL) and plasma |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increasing BMI was marginally and inversely associated with BAL adiponectin. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21332421 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Adiponectin [19F1] for Mouse/Rat/Human |
Record No:140
| ACCESS NO | 101268 |
| GENE | LEP |
| DESCRIPTION | leptin |
| NCBI ENTREZ ACCESS NO | 3952 |
| UNIPROT ACCESS NO | P41159 |
| ORGANISM | Human |
| SAMPLE | Broncho Alveolar Lavage (BAL) and plasma |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Obesity was associated with higher BAL and plasma leptin levels in asthmatics and controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21332421 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:141
| ACCESS NO | 101272 |
| GENE | HMGB1 |
| DESCRIPTION | High mobility group box 1 |
| NCBI ENTREZ ACCESS NO | 3146 |
| UNIPROT ACCESS NO | P09429 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | A neutrophilic chemoattractant and expressed significantly higher in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21041074 |
| DRUG TARGET | BE0003428 |
| MONCLONAL ANTIBODY | Anti-HMGB1 for Rat/Mouse/Human |
Record No:142
| ACCESS NO | 101273 |
| GENE | es RAGE (RAGE) |
| DESCRIPTION | Advanced glycosylation end product-specific receptor |
| NCBI ENTREZ ACCESS NO | 177 |
| UNIPROT ACCESS NO | Q15109 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Inhibitor of RAGE which in turn functions as a ligand for HMGB1. HMGB1 is a potent mediator of inflammation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21041074 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-RAGE for Mouse/Rat/Human |
Record No:143
| ACCESS NO | 101274 |
| GENE | ELANE |
| DESCRIPTION | Elastase |
| NCBI ENTREZ ACCESS NO | 1991 |
| UNIPROT ACCESS NO | P08246 |
| ORGANISM | Human |
| SAMPLE | Blood |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased expression in rapid onset asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20832159 |
| DRUG TARGET | BE0000394 |
| MONCLONAL ANTIBODY | Anti-Neutrophil Elastase for Human |
Record No:144
| ACCESS NO | 101275 |
| GENE | IL8 |
| DESCRIPTION | Interleukin 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| SAMPLE | Blood |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased expression in rapid onset asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20832159 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Mouse/Human |
Record No:145
| ACCESS NO | 101276 |
| GENE | ALB |
| DESCRIPTION | Serum Albumin |
| NCBI ENTREZ ACCESS NO | 213 |
| UNIPROT ACCESS NO | P02768 |
| ORGANISM | Human |
| SAMPLE | Blood |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased expression in rapid onset asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20832159 |
| DRUG TARGET | BE0000530 |
| MONCLONAL ANTIBODY | Anti-Human Serum Albumin for Human |
Record No:146
| ACCESS NO | 101277 |
| GENE | TPSAB1 |
| DESCRIPTION | Tryptase |
| NCBI ENTREZ ACCESS NO | 7177 |
| UNIPROT ACCESS NO | P20231 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | ImmunoCAP |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased significantly during aspirin desensitization. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20728206 |
| DRUG TARGET | BE0003736 |
| MONCLONAL ANTIBODY | Anti-Mast Cell Tryptase for Mouse/Rat/Human |
Record No:147
| ACCESS NO | 101278 |
| GENE | IL-4 |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | LINCOplex premixed kit |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Decreased significantly after aspirin treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20728206 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Rat |
Record No:148
| ACCESS NO | 101279 |
| GENE | MMP-9 |
| DESCRIPTION | Matrix metallopeptidase 9 |
| NCBI ENTREZ ACCESS NO | 4318 |
| UNIPROT ACCESS NO | P14780 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Decreased significantly after aspirin treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20728206 |
| DRUG TARGET | BE0000058 |
| MONCLONAL ANTIBODY | Anti-MMP9 for Human/Rat |
Record No:149
| ACCESS NO | 101280 |
| GENE | TIMP-1 |
| DESCRIPTION | TIMP metallopeptidase inhibitor 1 |
| NCBI ENTREZ ACCESS NO | 7076 |
| UNIPROT ACCESS NO | P01033 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Inhibitor of matrix metalloprotease 9. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20728206 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TIMP1 for Human |
Record No:150
| ACCESS NO | 101281 |
| GENE | FLT3LG |
| DESCRIPTION | Fms-related tyrosine kinase 3 ligand |
| NCBI ENTREZ ACCESS NO | 2323 |
| UNIPROT ACCESS NO | P49771 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Has an inverse correlation with IL-4. Hence decreases with IL4 increases. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20728206 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Flt3 ligand for Human/Monkey |
Record No:151
| ACCESS NO | 101285 |
| GENE | IL-1 beta |
| DESCRIPTION | Interleukin 1 Beta |
| NCBI ENTREZ ACCESS NO | 3553 |
| UNIPROT ACCESS NO | P01584 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0001051 |
| MONCLONAL ANTIBODY | Anti-IL1 beta Human |
Record No:152
| ACCESS NO | 101286 |
| GENE | IL-2 |
| DESCRIPTION | Interleukin 2 receptor alpha |
| NCBI ENTREZ ACCESS NO | 3558 |
| UNIPROT ACCESS NO | P60568 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0001029 |
| MONCLONAL ANTIBODY | Anti-IL2 for Human |
Record No:153
| ACCESS NO | 101287 |
| GENE | IL-4 |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:154
| ACCESS NO | 101288 |
| GENE | IL-6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | N/A |
Record No:155
| ACCESS NO | 101289 |
| GENE | IL-13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:156
| ACCESS NO | 101290 |
| GENE | IFN- gamma |
| DESCRIPTION | Interferon Gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | Anti-Interferon gamma for Mouse/Human |
Record No:157
| ACCESS NO | 101291 |
| GENE | TNF- alpha |
| DESCRIPTION | Tumor necrosis factor alpha |
| NCBI ENTREZ ACCESS NO | 7124 |
| UNIPROT ACCESS NO | P01375 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0000704 |
| MONCLONAL ANTIBODY | Anti-TNF alpha for Mouse/Human |
Record No:158
| ACCESS NO | 101292 |
| GENE | MIF |
| DESCRIPTION | Macrophage migration inhibitory factor |
| NCBI ENTREZ ACCESS NO | 4282 |
| UNIPROT ACCESS NO | P14174 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0001855 |
| MONCLONAL ANTIBODY | Anti-MIF for Mouse/Rat/Human |
Record No:159
| ACCESS NO | 101293 |
| GENE | sICAM |
| DESCRIPTION | Soluble intercellular adhesion molecule |
| NCBI ENTREZ ACCESS NO | 3383 |
| UNIPROT ACCESS NO | P05362 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Signifcant high expression in children with asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0001085 |
| MONCLONAL ANTIBODY | N/A |
Record No:160
| ACCESS NO | 101294 |
| GENE | sVCAM |
| DESCRIPTION | Soluble vascular adhesion molecule |
| NCBI ENTREZ ACCESS NO | 7412 |
| UNIPROT ACCESS NO | P19320 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Signifcant high expression in children with asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0001114 |
| MONCLONAL ANTIBODY | N/A |
Record No:161
| ACCESS NO | 101295 |
| GENE | MIP-1a |
| DESCRIPTION | Chemokine (C-C motif) ligand 3 |
| NCBI ENTREZ ACCESS NO | 6348 |
| UNIPROT ACCESS NO | P10147 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0002471 |
| MONCLONAL ANTIBODY | Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 for Human |
Record No:162
| ACCESS NO | 101296 |
| GENE | RANTES |
| DESCRIPTION | Chemokine (C-C motif) ligand 5 |
| NCBI ENTREZ ACCESS NO | 6352 |
| UNIPROT ACCESS NO | P13501 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0000975 |
| MONCLONAL ANTIBODY | Anti-RANTES for Human |
Record No:163
| ACCESS NO | 101297 |
| GENE | IP-10 |
| DESCRIPTION | Chemokine (C-X-C motif) ligand 10 |
| NCBI ENTREZ ACCESS NO | 3627 |
| UNIPROT ACCESS NO | P02778 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | Multiplex immunoassay technology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthmatic children. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20205697 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | Anti-IP10 for Human |
Record No:164
| ACCESS NO | 101299 |
| GENE | Mpo |
| DESCRIPTION | Myeloperoxidase |
| NCBI ENTREZ ACCESS NO | 303413 |
| UNIPROT ACCESS NO | D3ZGE2 |
| ORGANISM | Male Sprague–Dawley rats |
| SAMPLE | Broncho alveolar lavage fluid |
| TECHNIQUES | Biochemical tests |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased after OVA challenge but decreased on administering Vasoactive Intestinal Peptide. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19808073 |
| DRUG TARGET | BE0001075 |
| MONCLONAL ANTIBODY | Anti-Myeloperoxidase for Human |
Record No:165
| ACCESS NO | 101300 |
| GENE | Epo |
| DESCRIPTION | Eosinophil peroxidase |
| NCBI ENTREZ ACCESS NO | 24335 |
| UNIPROT ACCESS NO | P29676 |
| ORGANISM | Male Sprague–Dawley rats |
| SAMPLE | Broncho alveolar lavage fluid |
| TECHNIQUES | Biochemical tests |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased after OVA challenge but decreased on administering Vasoactive Intestinal Peptide. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19808073 |
| DRUG TARGET | BE0003555 |
| MONCLONAL ANTIBODY | N/A |
Record No:166
| ACCESS NO | 101301 |
| GENE | Ldh |
| DESCRIPTION | L-lactate dehydrogenase |
| NCBI ENTREZ ACCESS NO | 24533 |
| UNIPROT ACCESS NO | P04642 |
| ORGANISM | Male Sprague–Dawley rats |
| SAMPLE | Broncho alveolar lavage fluid |
| TECHNIQUES | Biochemical tests |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased after OVA challenge but decreased on administering Vasoactive Intestinal Peptide. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19808073 |
| DRUG TARGET | BE0001324 |
| MONCLONAL ANTIBODY | N/A |
Record No:167
| ACCESS NO | 101302 |
| GENE | MMP-9 |
| DESCRIPTION | Metalloproteinase-9 |
| NCBI ENTREZ ACCESS NO | 4318 |
| UNIPROT ACCESS NO | P14780 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19788537 |
| DRUG TARGET | BE0000058 |
| MONCLONAL ANTIBODY | Anti-MMP9 for Rat/Human |
Record No:168
| ACCESS NO | 101303 |
| GENE | TIMP-1 |
| DESCRIPTION | Tissue inhibitor metalloproteinase-1 |
| NCBI ENTREZ ACCESS NO | 7076 |
| UNIPROT ACCESS NO | P01033 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19788537 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TIMP1 for Human/Mouse |
Record No:169
| ACCESS NO | 101304 |
| GENE | IL-8 |
| DESCRIPTION | Interleukin-8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Upregulated in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19788537 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human/Rabbit/Pig |
Record No:170
| ACCESS NO | 101305 |
| GENE | IL-5 |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Time resolved flourimetry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Highly expressed in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19733295 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Mouse/Human |
Record No:171
| ACCESS NO | 101306 |
| GENE | IL-10 |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 3586 |
| UNIPROT ACCESS NO | P22301 |
| ORGANISM | Human |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Time resolved flourimetry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | A non TH2 cytokine but highly expressed in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19733295 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | N/A |
Record No:172
| ACCESS NO | 101307 |
| GENE | IL-12 |
| DESCRIPTION | Interleukin 12 |
| NCBI ENTREZ ACCESS NO | N/A |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Time resolved flourimetry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It plays a key role in Th1 polarization. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19733295 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:173
| ACCESS NO | 101308 |
| GENE | IL-13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Time resolved flourimetry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Highly expressed in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19733295 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human/Rat |
Record No:174
| ACCESS NO | 101309 |
| GENE | IFN- gamma |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Time resolved flourimetry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | A non TH2 cytokine but highly expressed in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19733295 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | N/A |
Record No:175
| ACCESS NO | 101312 |
| GENE | IL8 |
| DESCRIPTION | Interleukin-8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Did not show any marked expression change in severe and non severe asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19622091 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | N/A |
Record No:176
| ACCESS NO | 101313 |
| GENE | IL13 |
| DESCRIPTION | Interleukin-13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| SAMPLE | Sputum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Did not show any marked expression change in severe and non severe asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19622091 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human/Rat |
Record No:177
| ACCESS NO | 101330 |
| GENE | SLPI |
| DESCRIPTION | Secretory leukocyte peptidase inhibitor |
| NCBI ENTREZ ACCESS NO | 6590 |
| UNIPROT ACCESS NO | P03973 |
| ORGANISM | Human |
| SAMPLE | Nasal Lavage |
| TECHNIQUES | Western blot |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Protects tissues against environmental irritants through its anti-inflammatory properties. Cleaved SLPI is increased in asthma which is an indicative of chymase activity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19400896 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-SLPI for Human |
Record No:178
| ACCESS NO | 101331 |
| GENE | CMA1 |
| DESCRIPTION | Chymase |
| NCBI ENTREZ ACCESS NO | 1215 |
| UNIPROT ACCESS NO | P23946 |
| ORGANISM | Human |
| SAMPLE | Nasal Lavage |
| TECHNIQUES | Western blot |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | A protease by nature and produced by degranulation of mast cells. Increased in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19400896 |
| DRUG TARGET | BE0001038 |
| MONCLONAL ANTIBODY | Anti-Mast Cell Chymase for Human/Pig |
Record No:179
| ACCESS NO | 101332 |
| GENE | |
| DESCRIPTION | Tryptase |
| NCBI ENTREZ ACCESS NO | N/A |
| UNIPROT ACCESS NO | N/A |
| ORGANISM | Human |
| SAMPLE | Nasal Lavage |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | A protease by nature and produced by degranulation of mast cells. Increased in asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19400896 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Mast Cell Tryptase for Mouse/Human/Rat |
Record No:180
| ACCESS NO | 101333 |
| GENE | A2M |
| DESCRIPTION | Alpha2-macroglobulin |
| NCBI ENTREZ ACCESS NO | 2 |
| UNIPROT ACCESS NO | P01023 |
| ORGANISM | Human |
| SAMPLE | Nasal Lavage |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased after nasal allergen challenge. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19400896 |
| DRUG TARGET | BE0000910 |
| MONCLONAL ANTIBODY | Anti-alpha 2 Macroglobulin for Human |
Record No:181
| ACCESS NO | 101343 |
| GENE | IL-4 |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 16189 |
| UNIPROT ACCESS NO | P07750 |
| ORGANISM | Female BALB/c mice |
| SAMPLE | Thoracic Lymph node cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expression lowered after Andrographolide treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19201922 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti IL4 for Human |
Record No:182
| ACCESS NO | 101344 |
| GENE | IL-5 |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 16191 |
| UNIPROT ACCESS NO | P04401 |
| ORGANISM | Female BALB/c mice |
| SAMPLE | Thoracic Lymph node cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expression lowered after Andrographolide treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19201922 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Mouse/Human |
Record No:183
| ACCESS NO | 101345 |
| GENE | IL-13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 16163 |
| UNIPROT ACCESS NO | P20109 |
| ORGANISM | Female BALB/c mice |
| SAMPLE | Thoracic Lymph node cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expression lowered after Andrographolide treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19201922 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Mouse |
Record No:184
| ACCESS NO | 101346 |
| GENE | Eotaxin |
| DESCRIPTION | Chemokine (C-C motif) ligand 11 |
| NCBI ENTREZ ACCESS NO | 20292 |
| UNIPROT ACCESS NO | P48298 |
| ORGANISM | Female BALB/c mice |
| SAMPLE | Thoracic Lymph node cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expression lowered after Andrographolide treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19201922 |
| DRUG TARGET | BE0003389 |
| MONCLONAL ANTIBODY | Anti-Eotaxin for Human |
Record No:185
| ACCESS NO | 101347 |
| GENE | IFN- gamma |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 15978 |
| UNIPROT ACCESS NO | P01580 |
| ORGANISM | Female BALB/c mice |
| SAMPLE | Thoracic Lymph node cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expression increased after Andrographolide treatment. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19201922 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | Anti-Interferon gamma for Mouse/Human |
Record No:186
| ACCESS NO | 101350 |
| GENE | CRP |
| DESCRIPTION | C reactive protein |
| NCBI ENTREZ ACCESS NO | 1401 |
| UNIPROT ACCESS NO | P02741 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Higher in asthma compared in control. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18513240 |
| DRUG TARGET | BE0000877 |
| MONCLONAL ANTIBODY | Anti-C Reactive Protein for Human |
Record No:187
| ACCESS NO | 101351 |
| GENE | ALB |
| DESCRIPTION | Albumin |
| NCBI ENTREZ ACCESS NO | 213 |
| UNIPROT ACCESS NO | P02768 |
| ORGANISM | Human |
| SAMPLE | Exhaled Breath condensate |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Higher in smoking people compared to asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18513240 |
| DRUG TARGET | BE0000530 |
| MONCLONAL ANTIBODY | Anti-Human Serum Albumin for Human |
Record No:188
| ACCESS NO | 101396 |
| GENE | ECP |
| DESCRIPTION | Eosinophil cationic protein |
| NCBI ENTREZ ACCESS NO | 6037 |
| UNIPROT ACCESS NO | P12724 |
| ORGANISM | Human |
| SAMPLE | Blood serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Elevated in asthmatic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18504410 |
| DRUG TARGET | BE0000908 |
| MONCLONAL ANTIBODY | N/A |
Record No:189
| ACCESS NO | 101397 |
| GENE | ELANE |
| DESCRIPTION | Polymorphonuclear Granulocyte Elastase |
| NCBI ENTREZ ACCESS NO | 1991 |
| UNIPROT ACCESS NO | P08246 |
| ORGANISM | Human |
| SAMPLE | Blood plasma |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Elevated in asthmatic patients. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18504410 |
| DRUG TARGET | BE0000394 |
| MONCLONAL ANTIBODY | Anti-Neutrophil Elastase for Human |
Record No:190
| ACCESS NO | 101398 |
| GENE | CD203c |
| DESCRIPTION | Ectonucleotide pyrophosphatase/phosphodiesterase 3 |
| NCBI ENTREZ ACCESS NO | 5169 |
| UNIPROT ACCESS NO | O14638 |
| ORGANISM | Human |
| SAMPLE | Blood |
| TECHNIQUES | Flow cytometry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Reduced expression after rush immunotherapy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18504407 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-ENPP3 for Human |
Record No:191
| ACCESS NO | 101527 |
| GENE | LEP |
| DESCRIPTION | Leptin |
| NCBI ENTREZ ACCESS NO | 3952 |
| UNIPROT ACCESS NO | P41159 |
| ORGANISM | Human |
| SAMPLE | EDTA added blood plasma |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | High leptin were associated with increased persistence of asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18331416 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:192
| ACCESS NO | 101528 |
| GENE | ADIPOQ |
| DESCRIPTION | Adiponectin |
| NCBI ENTREZ ACCESS NO | 9370 |
| UNIPROT ACCESS NO | Q15848 |
| ORGANISM | Human |
| SAMPLE | EDTA added blood plasma |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Low adiponectin is associated with rhinoconjunctivitis and hay fever in girls and higher prevalence of asthma in general. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18331416 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Adiponectin for Mouse/Rat/Human |
Record No:193
| ACCESS NO | 101529 |
| GENE | CRP |
| DESCRIPTION | C-reactive protein |
| NCBI ENTREZ ACCESS NO | 1401 |
| UNIPROT ACCESS NO | P02741 |
| ORGANISM | Human |
| SAMPLE | Exhaled breath condensate |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Significantly higher in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18513240 |
| DRUG TARGET | BE0000877 |
| MONCLONAL ANTIBODY | Anti-C Reactive Protein for Human |
Record No:194
| ACCESS NO | 101530 |
| GENE | ALB |
| DESCRIPTION | Albumin |
| NCBI ENTREZ ACCESS NO | 213 |
| UNIPROT ACCESS NO | P02768 |
| ORGANISM | Human |
| SAMPLE | Exhaled breath condensate |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Higher in smoking group. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18513240 |
| DRUG TARGET | BE0000530 |
| MONCLONAL ANTIBODY | Anti-Human Serum Albumin for Human |
Record No:195
| ACCESS NO | 101531 |
| GENE | CRP |
| DESCRIPTION | C-reactive protein |
| NCBI ENTREZ ACCESS NO | 1401 |
| UNIPROT ACCESS NO | P02741 |
| ORGANISM | Human |
| SAMPLE | Venous blood |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Decreased in asthmatics after etanercept administration. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18245148 |
| DRUG TARGET | BE0000877 |
| MONCLONAL ANTIBODY | Anti-C Reactive Protein for Human |
Record No:196
| ACCESS NO | 101532 |
| GENE | ALB |
| DESCRIPTION | Albumin |
| NCBI ENTREZ ACCESS NO | 213 |
| UNIPROT ACCESS NO | P02768 |
| ORGANISM | Human |
| SAMPLE | Venous blood |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Decreased in asthmatics after etanercept administration. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 18245148 |
| DRUG TARGET | BE0000530 |
| MONCLONAL ANTIBODY | Anti-Human Serum Albumin for Human |
Record No:197
| ACCESS NO | 101533 |
| GENE | STAT1 |
| DESCRIPTION | Signal transducer and activator of transcription 1 |
| NCBI ENTREZ ACCESS NO | 6772 |
| UNIPROT ACCESS NO | P42224 |
| ORGANISM | Human |
| SAMPLE | CD4+ and CD161+ T cells |
| TECHNIQUES | FACS |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Phospho-STAT1 was increased in asthmatic subjects. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919711 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-STAT1 for Mouse/Rat/Humam |
Record No:198
| ACCESS NO | 101534 |
| GENE | STAT6 |
| DESCRIPTION | Signal transducer and activator of transcription 6 |
| NCBI ENTREZ ACCESS NO | 6778 |
| UNIPROT ACCESS NO | P42226 |
| ORGANISM | Human |
| SAMPLE | CD4+ and CD161+ T cells |
| TECHNIQUES | FACS |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Phospho-STAT6 was increased in asthmatic subjects. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17919711 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-STAT6 for mouse/Human |
Record No:199
| ACCESS NO | 101535 |
| GENE | IFN-gamma |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| SAMPLE | Exhaled breath condensate |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Has pro inflammatory effects and is responsible for recruiting infammatory cytokines . Higher expression in asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17845410 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | Anti-Interferon gamma for Human |
Record No:200
| ACCESS NO | 101536 |
| GENE | IL-4 |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| SAMPLE | Exhaled breath condensate |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Higher expression in asthmatics compared to controls. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17845410 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | N/A |
Record No:201
| ACCESS NO | 101537 |
| GENE | IP-10 |
| DESCRIPTION | Induced Protein 10 |
| NCBI ENTREZ ACCESS NO | 3627 |
| UNIPROT ACCESS NO | P02778 |
| ORGANISM | Human |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Highly expressed in virus induced asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17628646 |
| DRUG TARGET | BE0000934 |
| MONCLONAL ANTIBODY | Anti-IP10 for Mouse/Human |
Record No:202
| ACCESS NO | 101538 |
| GENE | RANTES(CCL5) |
| DESCRIPTION | chemokine (C-C motif) ligand 5 |
| NCBI ENTREZ ACCESS NO | 6352 |
| UNIPROT ACCESS NO | P13501 |
| ORGANISM | Human |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Important chemoattractant for eosinophils and overexpressed in virus induced asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17628646 |
| DRUG TARGET | BE0000975 |
| MONCLONAL ANTIBODY | Anti-RANTES for Human |
Record No:203
| ACCESS NO | 101539 |
| GENE | IL-6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expressed in virus induced asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17628646 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | N/A |
Record No:204
| ACCESS NO | 101540 |
| GENE | IL-8(CXCL8) |
| DESCRIPTION | Interleukin 8 |
| NCBI ENTREZ ACCESS NO | 3576 |
| UNIPROT ACCESS NO | P10145 |
| ORGANISM | Human |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expressed in virus induced asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17628646 |
| DRUG TARGET | BE0000961 |
| MONCLONAL ANTIBODY | Anti-IL8 for Human/Pig |
Record No:205
| ACCESS NO | 101541 |
| GENE | TNF-alpha |
| DESCRIPTION | Tumor necrosis factor alpha |
| NCBI ENTREZ ACCESS NO | 7124 |
| UNIPROT ACCESS NO | P01375 |
| ORGANISM | Human |
| SAMPLE | Bronchial epithelial cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Expressed in virus induced asthma. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17628646 |
| DRUG TARGET | BE0000704 |
| MONCLONAL ANTIBODY | Anti-TNF alpha for Mouse/Human |
Record No:206
| ACCESS NO | 101542 |
| GENE | Gsk-3b |
| DESCRIPTION | Glycogen Synthase Kinase-3b |
| NCBI ENTREZ ACCESS NO | 56637 |
| UNIPROT ACCESS NO | Q9WV60 |
| ORGANISM | Female Balb/c Mice |
| SAMPLE | Bronchial epithelial cell lysate |
| TECHNIQUES | Western blotting |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | A regulator Nf kappa beta which involved in asthma pathogenesis. Inhibition of Gsk-3b decreases asthma excacerbation. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 17556716 |
| DRUG TARGET | BE0001065 |
| MONCLONAL ANTIBODY | Anti-GSK3 beta for Mouse/Human |
Record No:207
| ACCESS NO | 101662 |
| GENE | IL-6 |
| DESCRIPTION | Interleukin 6 |
| NCBI ENTREZ ACCESS NO | 3569 |
| UNIPROT ACCESS NO | P05231 |
| ORGANISM | Human |
| SAMPLE | PBMC |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Neonatal responses were lower for children positive to Fel d1. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 14616132 |
| DRUG TARGET | BE0000918 |
| MONCLONAL ANTIBODY | N/A |
Record No:208
| ACCESS NO | 101663 |
| GENE | IL-13 |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| SAMPLE | PBMC |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Lower expression in children at birth who show positive SPT to house dust mite. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 14616132 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Human |
Record No:209
| ACCESS NO | 101664 |
| GENE | IFN- gamma |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| SAMPLE | PBMC |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Weaker IFN gamma response in neonatal patients having a history to allergy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 14616132 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | Anti-Interferon gamma for Human |
Record No:210
| ACCESS NO | 101666 |
| GENE | ECP(RNASE3) |
| DESCRIPTION | Eosinophil cationic protein |
| NCBI ENTREZ ACCESS NO | 6037 |
| UNIPROT ACCESS NO | P12724 |
| ORGANISM | Human |
| SAMPLE | Blood serum |
| TECHNIQUES | CAP FEIA (Pharmacia-Upjohn Uppsala Sweden) |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 11097312 |
| DRUG TARGET | BE0000908 |
| MONCLONAL ANTIBODY | N/A |
Record No:211
| ACCESS NO | 101667 |
| GENE | Kcna3 |
| DESCRIPTION | Voltage-gated KV1.3 potassium channel |
| NCBI ENTREZ ACCESS NO | 29731 |
| UNIPROT ACCESS NO | P15384 |
| ORGANISM | Rat |
| SAMPLE | Mononuclear cells isolated from Broncho Alveolar L |
| TECHNIQUES | Patch clamp electrophysiology together with flow c |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | KV1.3 channels on CCR7 effector memory T lymphocytes are major players in lung inflammation that characterizes allergic asthma. Blocking KV1.3 channels reduced the severity of an ovalbumin-induced model of asthma in rats and therefore KV1.3 channels are attractive targets for immunomodulation and the treatment of allergic asthma. This study investigated the inhibitory effect of ShK-186 drug on this ion channel to effectively reduce the severity of allergic asthma symptoms. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24644290 |
| DRUG TARGET | BE0004105 |
| MONCLONAL ANTIBODY | Anti-KCNA3 for Mouse/Rat/Human |
Record No:212
| ACCESS NO | 101668 |
| GENE | Parp1 |
| DESCRIPTION | Poly (ADP-ribose) polymerase 1 |
| NCBI ENTREZ ACCESS NO | 25591 |
| UNIPROT ACCESS NO | P27008 |
| ORGANISM | Rat |
| SAMPLE | Lung tissue |
| TECHNIQUES | Ferric Reducing Ability Assay and Poly(ADP-ribosyl |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Minocycline-treated/ovalbumin-challenged mice showed reduction in poly(ADP-ribose) immunoreactivity in lung and it correlates with decreased oxidative DNA damage. However the drug can not block direct PARP activation in lungs of N-methyl-N -nitro-N-nitroso-guanidine-treated mice or H2O2-treated cells. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23184953 |
| DRUG TARGET | BE0001717 |
| MONCLONAL ANTIBODY | N/A |
Record No:213
| ACCESS NO | 101674 |
| GENE | Tnfaip6 (TSG-6) |
| DESCRIPTION | TNF-stimulated gene-6 |
| NCBI ENTREZ ACCESS NO | 21930 |
| UNIPROT ACCESS NO | O08859 |
| ORGANISM | Mouse |
| SAMPLE | Lung tissue and Broncho Alveolar Lavage (BAL) cell |
| TECHNIQUES | Immunoassay (ELISA and Immunohistochemistry) and B |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | TSG-6 is dispensable for the induction of Th2 immunity but is essential for the robust increase in pulmonary Hyaluronan deposition and propagation of acute eosinophilic pulmonary inflammation. In TSG-6 knock out mice the lack of TSG-6 results in diminished HA accumulation and decreased inflammation and airway hyperresponsiveness. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23118230 |
| DRUG TARGET | BE0004641 |
| MONCLONAL ANTIBODY | N/A |
Record No:214
| ACCESS NO | 101690 |
| GENE | Mfge8 |
| DESCRIPTION | Milk Fat Globule-EGF factor 8 |
| NCBI ENTREZ ACCESS NO | 17304 |
| UNIPROT ACCESS NO | P21956 |
| ORGANISM | Mouse |
| SAMPLE | Smooth muscle cells of lung tissue |
| TECHNIQUES | Standard molecular biology and cell biology techni |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | In absence of this gene the airway hyper-responsiveness is highly exaggerated. Treatment with recombinant Mfge8 causes attenuation of airway inflammation by inhibiting IL-13–induced NF-κB activation and induction of RhoA. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 23269839 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Milk Fat Globule 1 [EDM45] for Human |
Record No:215
| ACCESS NO | 101691 |
| GENE | Grp |
| DESCRIPTION | Gastrin-releasing peptide |
| NCBI ENTREZ ACCESS NO | 225642 |
| UNIPROT ACCESS NO | Q8R1I2 |
| ORGANISM | Mouse |
| SAMPLE | Whole lung |
| TECHNIQUES | qRT-PCR and immunochemistry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It is a pro-inflammatory peptide by pulmonary neuroendocrine cells in asthmatic lung. Treatment with blocking agent 77427 and blocking antiobody 2A11 abrogates the airway hyper responsiveness and inflammation. Targated blockade of this gene is even better effective than dexamethasone therapy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 21252304 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Grp75 [JG1] for Mouse/Rat/Human |
Record No:216
| ACCESS NO | 101692 |
| GENE | Postn |
| DESCRIPTION | Periostin |
| NCBI ENTREZ ACCESS NO | 50706 |
| UNIPROT ACCESS NO | Q62009 |
| ORGANISM | Mouse |
| SAMPLE | Airway Epithelial Cells |
| TECHNIQUES | Standard molecular biology and cell biology techni |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | It stimulates TGF beta signaling pathway in a mechanism involving matrix metalloproteinases 2 and 9. Over expression of periostin causes TGF beta dependent secretion of type 1 collagen by airway fibroblasts. Periostin alters collagen fibrillogenesis or cross-linking and leads to stiffening of the matrix. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 20660732 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-Periostin [EPR6989(N)(B)] for human |
Record No:217
| ACCESS NO | 101693 |
| GENE | ATP2A2 (SARCA2) |
| DESCRIPTION | Sarco/endoplasmic reticulum Calcium pump |
| NCBI ENTREZ ACCESS NO | 488 |
| UNIPROT ACCESS NO | P16615 |
| ORGANISM | Human |
| SAMPLE | Airway smooth muscle cells (ASM) |
| TECHNIQUES | Immunochemistry and rela time PCR and cell biology |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | SERCA2 mRNA and protein expression is reduced in ASM cells from subjects with moderately severe asthma. Rises in intracellular calcium following cell surface receptor-induced SR activation or inhibition of SERCA-mediated Calcium re-uptake were attenuated in ASM cells from asthmatics. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19541629 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-SERCA2 ATPase [2A7-A1] for Mouse/Rat/Human |
Record No:218
| ACCESS NO | 101694 |
| GENE | Trapa1 |
| DESCRIPTION | Transient receptor potential cation channel subfamily 1 |
| NCBI ENTREZ ACCESS NO | 277328 |
| UNIPROT ACCESS NO | Q8BLA8 |
| ORGANISM | Mouse |
| SAMPLE | Lung tissue and Broncho Alveolar Lavage (BAL) flui |
| TECHNIQUES | Immunoassay and real time PCR |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Genetic ablation of TRPA1 inhibited allergen-induced leukocyte infiltration in the airways and abolished airway hyperreactivity. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 19458046 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-TAPA1 [M38] for Rabbit/Human |
Record No:219
| ACCESS NO | 101968 |
| GENE | CD40L |
| DESCRIPTION | CD40 ligand |
| NCBI ENTREZ ACCESS NO | 959 |
| UNIPROT ACCESS NO | P29965 |
| ORGANISM | Human |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Flow cytometry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Downregulated after specific immunotherapy.Interacts with CD40 and is the key signal for isotype class switching towards IgE. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24834772 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-CD40L for Mouse/Human |
Record No:220
| ACCESS NO | 101969 |
| GENE | IFN- gamma (IFNG) |
| DESCRIPTION | Interferon gamma |
| NCBI ENTREZ ACCESS NO | 3458 |
| UNIPROT ACCESS NO | P01579 |
| ORGANISM | Human |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Flow cytometry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased after specific immunotherapy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24834772 |
| DRUG TARGET | BE0000944 |
| MONCLONAL ANTIBODY | Anti-Interferon gamma for Mouse/Rat/Human |
Record No:221
| ACCESS NO | 101970 |
| GENE | IL-10 |
| DESCRIPTION | Interleukin 10 |
| NCBI ENTREZ ACCESS NO | 3586 |
| UNIPROT ACCESS NO | P22301 |
| ORGANISM | Human |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Flow cytometry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased after specific immunotherapy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24834772 |
| DRUG TARGET | BE0002484 |
| MONCLONAL ANTIBODY | N/A |
Record No:222
| ACCESS NO | 101971 |
| GENE | TGF-beta |
| DESCRIPTION | Tumour growth factor Beta |
| NCBI ENTREZ ACCESS NO | 7040 |
| UNIPROT ACCESS NO | P01137 |
| ORGANISM | Human |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | Flow cytometry |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased after specific immunotherapy. |
| GEO_PRIDE_ACCESS_NO | N/A |
| REFERENCE | 24834772 |
| DRUG TARGET | BE0000984 |
| MONCLONAL ANTIBODY | Anti-TGF beta 1 for Mouse/Rat/Human |
Record No:223
| ACCESS NO | 102064 |
| GENE | IL4(Il-4) |
| DESCRIPTION | Interleukin 4 |
| NCBI ENTREZ ACCESS NO | 3565 |
| UNIPROT ACCESS NO | P05112 |
| ORGANISM | Human |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased in monozygotic twins suffering from allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | GSE37146 |
| REFERENCE | 22515200 |
| DRUG TARGET | |
| MONCLONAL ANTIBODY | Anti-IL4 for Mouse |
Record No:224
| ACCESS NO | 102065 |
| GENE | IL5(IL-5) |
| DESCRIPTION | Interleukin 5 |
| NCBI ENTREZ ACCESS NO | 3567 |
| UNIPROT ACCESS NO | P05113 |
| ORGANISM | Human |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased in monozygotic twins suffering from allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | GSE37146 |
| REFERENCE | 22515200 |
| DRUG TARGET | BE0001208 |
| MONCLONAL ANTIBODY | Anti-IL5 for Mouse/Human |
Record No:225
| ACCESS NO | 102066 |
| GENE | IL13(IL-13) |
| DESCRIPTION | Interleukin 13 |
| NCBI ENTREZ ACCESS NO | 3596 |
| UNIPROT ACCESS NO | P35225 |
| ORGANISM | Human |
| SAMPLE | Peripheral blood mononuclear cells |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| COMMENTS | Increased in monozygotic twins suffering from allergic rhinitis. |
| GEO_PRIDE_ACCESS_NO | GSE37146 |
| REFERENCE | 22515200 |
| DRUG TARGET | BE0002438 |
| MONCLONAL ANTIBODY | Anti-IL13 for Mouse/Rat/Human |