Query 'AF-2 transcriptional activation domain' matched 102 Records
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Record No : 1 |
| Instance ID | 11363 | | Regular Expression | LxxLL | | Motif Instance | LEGLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 21-25 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21363 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box I) in NRIP1 required for the ligand-dependent binding to the oestrogen receptor |
Record No : 2 |
| Instance ID | 11364 | | Regular Expression | LxxLL | | Motif Instance | LEGLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 21-25 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21364 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box I) in NRIP1 required for the ligand-dependent binding to the retinoic acid receptor |
Record No : 3 |
| Instance ID | 11365 | | Regular Expression | LxxLL | | Motif Instance | LEGLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 21-25 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21365 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box I) in NRIP1 required for the ligand-dependent binding to the retinoid X receptor |
Record No : 4 |
| Instance ID | 11366 | | Regular Expression | LxxLL | | Motif Instance | LASLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 133-137 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21366 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box II) in NRIP1 required for the ligand-dependent binding to the oestrogen receptor |
Record No : 5 |
| Instance ID | 11367 | | Regular Expression | LxxLL | | Motif Instance | LASLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 133-137 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21367 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box II) in NRIP1 required for the ligand-dependent binding to the retinoic acid receptor |
Record No : 6 |
| Instance ID | 11368 | | Regular Expression | LxxLL | | Motif Instance | LASLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 133-137 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21368 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box II) in NRIP1 required for the ligand-dependent binding to the retinoid X receptor |
Record No : 7 |
| Instance ID | 11369 | | Regular Expression | LxxLL | | Motif Instance | LKTLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 185-189 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21369 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box III) in NRIP1 required for the ligand-dependent binding to the oestrogen receptor |
Record No : 8 |
| Instance ID | 11370 | | Regular Expression | LxxLL | | Motif Instance | LKTLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 185-189 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21370 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box III) in NRIP1 required for the ligand-dependent binding to the retinoid X receptor |
Record No : 9 |
| Instance ID | 11371 | | Regular Expression | LxxLL | | Motif Instance | LALLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 266-270 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21371 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IV) in NRIP1 required for the ligand-dependent binding to the oestrogen receptor |
Record No : 10 |
| Instance ID | 11372 | | Regular Expression | LxxLL | | Motif Instance | LALLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 266-270 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21372 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IV) in NRIP1 required for the ligand-dependent binding to the retinoic acid receptor |
Record No : 11 |
| Instance ID | 11373 | | Regular Expression | LxxLL | | Motif Instance | LALLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 266-270 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21373 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IV) in NRIP1 required for the ligand-dependent binding to the retinoid X receptor |
Record No : 12 |
| Instance ID | 11374 | | Regular Expression | LxxLL | | Motif Instance | LLHLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 380-384 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | X-ray crystallography; Y2H | | Interaction ID | 21374 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741, 16990259 | | Comments | Core LXXLL motif sequence (NR Box V) in NRIP1 required for the ligand-dependent binding to the oestrogen receptor |
Record No : 13 |
| Instance ID | 11375 | | Regular Expression | LxxLL | | Motif Instance | LLHLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 380-384 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | X-ray crystallography; Y2H | | Interaction ID | 21375 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741, 16990259 | | Comments | Core LXXLL motif sequence (NR Box V) in NRIP1 required for the ligand-dependent binding to the retinoic acid receptor |
Record No : 14 |
| Instance ID | 11376 | | Regular Expression | LxxLL | | Motif Instance | LQLLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 501-505 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21376 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box VI) in NRIP1 required for the ligand-dependent binding to the oestrogen receptor |
Record No : 15 |
| Instance ID | 11377 | | Regular Expression | LxxLL | | Motif Instance | LQLLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 501-505 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21377 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box VI) in NRIP1 required for the ligand-dependent binding to the retinoic acid receptor |
Record No : 16 |
| Instance ID | 11378 | | Regular Expression | LxxLL | | Motif Instance | LQLLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 501-505 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21378 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box VI) in NRIP1 required for the ligand-dependent binding to the retinoid X receptor |
Record No : 17 |
| Instance ID | 11379 | | Regular Expression | LxxLL | | Motif Instance | LQLLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 713-717 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21379 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box VII) in NRIP1 required for the ligand-dependent binding to the oestrogen receptor |
Record No : 18 |
| Instance ID | 11380 | | Regular Expression | LxxLL | | Motif Instance | LQLLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 713-717 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21380 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box VII) in NRIP1 required for the ligand-dependent binding to the retinoic acid receptor |
Record No : 19 |
| Instance ID | 11381 | | Regular Expression | LxxLL | | Motif Instance | LQLLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 713-717 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21381 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box VII) in NRIP1 required for the ligand-dependent binding to the retinoid X receptor |
Record No : 20 |
| Instance ID | 11382 | | Regular Expression | LxxLL | | Motif Instance | LSRLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 819-823 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21382 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box VIII) in NRIP1 required for the ligand-dependent binding to the oestrogen receptor |
Record No : 21 |
| Instance ID | 11383 | | Regular Expression | LxxLL | | Motif Instance | LSRLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 819-823 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21383 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box VIII) in NRIP1 required for the ligand-dependent binding to the retinoic acid receptor |
Record No : 22 |
| Instance ID | 11384 | | Regular Expression | LxxLL | | Motif Instance | LSRLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 819-823 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21384 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box VIII) in NRIP1 required for the ligand-dependent binding to the retinoid X receptor |
Record No : 23 |
| Instance ID | 11385 | | Regular Expression | LxxLL | | Motif Instance | LKQLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 936-940 | | Critical Residues | P1; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21385 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IX) in NRIP1 required for the ligand-dependent binding to the oestrogen receptor |
Record No : 24 |
| Instance ID | 11386 | | Regular Expression | LxxLL | | Motif Instance | LKQLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 936-940 | | Critical Residues | P1; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21386 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IX) in NRIP1 required for the ligand-dependent binding to the retinoic acid receptor |
Record No : 25 |
| Instance ID | 11387 | | Regular Expression | LxxLL | | Motif Instance | LKQLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 936-940 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21387 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IX) in NRIP1 required for the ligand-dependent binding to the retinoid X receptor |
Record No : 26 |
| Instance ID | 11388 | | Regular Expression | LxxLL | | Motif Instance | LVQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 633-637 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21388 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box I) in NCOA1 required for the ligand-dependent binding to the Glucocorticoid receptor |
Record No : 27 |
| Instance ID | 11389 | | Regular Expression | LxxLL | | Motif Instance | LVQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 633-637 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21389 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box I) in NCOA1 required for the ligand-dependent binding to the Estrogen receptor |
Record No : 28 |
| Instance ID | 11390 | | Regular Expression | LxxLL | | Motif Instance | LVQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 633-637 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21390 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box I) in NCOA1 required for the ligand-dependent binding to the Mineralocorticoid receptor |
Record No : 29 |
| Instance ID | 11391 | | Regular Expression | LxxLL | | Motif Instance | LVQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 633-637 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21391 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box I) in NCOA1 required for the ligand-dependent binding to the Progesterone receptor |
Record No : 30 |
| Instance ID | 11392 | | Regular Expression | LxxLL | | Motif Instance | LVQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 633-637 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21392 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box I) in NCOA1 required for the ligand-dependent binding to the Vitamin D3 receptor |
Record No : 31 |
| Instance ID | 11393 | | Regular Expression | LxxLL | | Motif Instance | LVQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 633-637 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21393 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box I) in NCOA1 required for the ligand-dependent binding to the Retinoic acid receptor |
Record No : 32 |
| Instance ID | 11394 | | Regular Expression | LxxLL | | Motif Instance | LVQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 633-637 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21394 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box I) in NCOA1 required for the ligand-dependent binding to the Retinoid X receptor |
Record No : 33 |
| Instance ID | 11395 | | Regular Expression | LxxLL | | Motif Instance | LVQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 633-637 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21395 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box I) in NCOA1 required for the ligand-dependent binding to the Thyroid hormone receptor |
Record No : 34 |
| Instance ID | 11396 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 690-694 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21396 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA1 required for the ligand-dependent binding to the Glucocorticoid receptor |
Record No : 35 |
| Instance ID | 11397 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 690-694 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21397 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA1 required for the ligand-dependent binding to the Estrogen receptor |
Record No : 36 |
| Instance ID | 11398 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 690-694 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21398 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA1 required for the ligand-dependent binding to the Mineralocorticoid receptor |
Record No : 37 |
| Instance ID | 11399 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 690-694 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21399 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA1 required for the ligand-dependent binding to the Progesterone receptor |
Record No : 38 |
| Instance ID | 11400 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 690-694 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21400 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA1 required for the ligand-dependent binding to the Vitamin D3 receptor |
Record No : 39 |
| Instance ID | 11401 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 690-694 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21401 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA1 required for the ligand-dependent binding to the Retinoic acid receptor |
Record No : 40 |
| Instance ID | 11402 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 690-694 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21402 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA1 required for the ligand-dependent binding to the Retinoid X receptor |
Record No : 41 |
| Instance ID | 11403 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 690-694 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21403 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA1 required for the ligand-dependent binding to the Thyroid hormone receptor |
Record No : 42 |
| Instance ID | 11404 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 749-753 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21404 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA1 required for the ligand-dependent binding to the Glucocorticoid receptor |
Record No : 43 |
| Instance ID | 11405 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 749-753 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21405 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA1 required for the ligand-dependent binding to the Estrogen receptor |
Record No : 44 |
| Instance ID | 11406 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 749-753 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21406 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA1 required for the ligand-dependent binding to the Mineralocorticoid receptor |
Record No : 45 |
| Instance ID | 11407 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 749-753 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21407 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA1 required for the ligand-dependent binding to the Progesterone receptor |
Record No : 46 |
| Instance ID | 11408 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 749-753 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21408 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA1 required for the ligand-dependent binding to the Vitamin D3 receptor |
Record No : 47 |
| Instance ID | 11409 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 749-753 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21409 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA1 required for the ligand-dependent binding to the Retinoic acid receptor |
Record No : 48 |
| Instance ID | 11410 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 749-753 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21410 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA1 required for the ligand-dependent binding to the Retinoid X receptor |
Record No : 49 |
| Instance ID | 11411 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 749-753 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21411 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA1 required for the ligand-dependent binding to the Thyroid hormone receptor |
Record No : 50 |
| Instance ID | 11412 | | Regular Expression | LxxLL | | Motif Instance | LQQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1435-1439 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21412 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IV) in NCOA1 required for the ligand-dependent binding to the Glucocorticoid receptor |
Record No : 51 |
| Instance ID | 11413 | | Regular Expression | LxxLL | | Motif Instance | LQQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1435-1439 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21413 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IV) in NCOA1 required for the ligand-dependent binding to the Estrogen receptor |
Record No : 52 |
| Instance ID | 11414 | | Regular Expression | LxxLL | | Motif Instance | LQQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1435-1439 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21414 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IV) in NCOA1 required for the ligand-dependent binding to the Androgen receptor |
Record No : 53 |
| Instance ID | 11415 | | Regular Expression | LxxLL | | Motif Instance | LQQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1435-1439 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21415 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IV) in NCOA1 required for the ligand-dependent binding to the Mineralocorticoid receptor |
Record No : 54 |
| Instance ID | 11416 | | Regular Expression | LxxLL | | Motif Instance | LQQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1435-1439 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21416 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IV) in NCOA1 required for the ligand-dependent binding to the Progesterone receptor |
Record No : 55 |
| Instance ID | 11417 | | Regular Expression | LxxLL | | Motif Instance | LQQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1435-1439 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21417 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IV) in NCOA1 required for the ligand-dependent binding to the Vitamin D3 receptor |
Record No : 56 |
| Instance ID | 11418 | | Regular Expression | LxxLL | | Motif Instance | LQQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1435-1439 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21418 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IV) in NCOA1 required for the ligand-dependent binding to the Retinoic acid receptor |
Record No : 57 |
| Instance ID | 11419 | | Regular Expression | LxxLL | | Motif Instance | LQQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1435-1439 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21419 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IV) in NCOA1 required for the ligand-dependent binding to the Retinoid X receptor |
Record No : 58 |
| Instance ID | 11420 | | Regular Expression | LxxLL | | Motif Instance | LQQLL | | Bait Uniprot Accession | Q15788 | | Bait Uniprot Identifier | NCOA1_HUMAN | | Bait Gene Name | NCOA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1435-1439 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 21420 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902, 9482670, 11078741 | | Comments | Core LXXLL motif sequence (NR Box IV) in NCOA1 required for the ligand-dependent binding to the Thyroid hormone receptor |
Record No : 59 |
| Instance ID | 11421 | | Regular Expression | LxxLL | | Motif Instance | LLQLL | | Bait Uniprot Accession | Q15596 | | Bait Uniprot Identifier | NCOA2_HUMAN | | Bait Gene Name | NCOA2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 641-645 | | Critical Residues | P1; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | SPR | | Interaction ID | 21421 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11937504 | | Comments | NR Box B1 region (641-645) of human Nuclear receptor coactivator 2 required for the ligand-dependent binding to the AF-2 transcriptional activation domain of human Estrogen receptor |
Record No : 60 |
| Instance ID | 11422 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q15596 | | Bait Uniprot Identifier | NCOA2_HUMAN | | Bait Gene Name | NCOA2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 690-694 | | Critical Residues | P1; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | X-ray crystallography; SPR; Mutational analysis | | Interaction ID | 21422 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11937504 | | Comments | NR Box B2 region (690-694) of human Nuclear receptor coactivator 2 required for the ligand-dependent binding to the AF-2 transcriptional activation domain of human Estrogen receptor |
Record No : 61 |
| Instance ID | 11423 | | Regular Expression | LxxYL | | Motif Instance | LLRYL | | Bait Uniprot Accession | Q15596 | | Bait Uniprot Identifier | NCOA2_HUMAN | | Bait Gene Name | NCOA2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 744-748 | | Critical Residues | P1; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | X-ray crystallography; SPR | | Interaction ID | 21423 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11937504 | | Comments | NR Box B3 region (744-748) of human Nuclear receptor coactivator 2 required for the ligand-dependent binding to the AF-2 transcriptional activation domain of human Estrogen receptor |
Record No : 62 |
| Instance ID | 11424 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 690-694 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21424 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA2 required for the ligand-dependent binding to the Glucocorticoid receptor |
Record No : 63 |
| Instance ID | 11425 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 690-694 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21425 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA2 required for the ligand-dependent binding to the Estrogen receptor |
Record No : 64 |
| Instance ID | 11426 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 690-694 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21426 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA2 required for the ligand-dependent binding to the Mineralocorticoid receptor |
Record No : 65 |
| Instance ID | 11427 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 690-694 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21427 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA2 required for the ligand-dependent binding to the Progesterone receptor |
Record No : 66 |
| Instance ID | 11428 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 690-694 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21428 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA2 required for the ligand-dependent binding to the Vitamin D3 receptor |
Record No : 67 |
| Instance ID | 11429 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 690-694 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21429 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA2 required for the ligand-dependent binding to the Retinoic acid receptor |
Record No : 68 |
| Instance ID | 11430 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 690-694 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21430 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA2 required for the ligand-dependent binding to the Retinoid X receptor |
Record No : 69 |
| Instance ID | 11431 | | Regular Expression | LxxLL | | Motif Instance | LHRLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 690-694 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21431 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box II) in NCOA2 required for the ligand-dependent binding to the Thyroid hormone receptor |
Record No : 70 |
| Instance ID | 11432 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 745-749 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21432 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA2 required for the ligand-dependent binding to the Glucocorticoid receptor |
Record No : 71 |
| Instance ID | 11433 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 745-749 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21433 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA2 required for the ligand-dependent binding to the Estrogen receptor |
Record No : 72 |
| Instance ID | 11434 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 745-749 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21434 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA2 required for the ligand-dependent binding to the Androgen receptor |
Record No : 73 |
| Instance ID | 11435 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 745-749 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21435 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA2 required for the ligand-dependent binding to the Mineralocorticoid receptor |
Record No : 74 |
| Instance ID | 11436 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 745-749 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21436 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA2 required for the ligand-dependent binding to the Progesterone receptor |
Record No : 75 |
| Instance ID | 11437 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 745-749 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21437 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA2 required for the ligand-dependent binding to the Vitamin D3 receptor |
Record No : 76 |
| Instance ID | 11438 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 745-749 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21438 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA2 required for the ligand-dependent binding to the Retinoic acid receptor |
Record No : 77 |
| Instance ID | 11439 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 745-749 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21439 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA2 required for the ligand-dependent binding to the Retinoid X receptor |
Record No : 78 |
| Instance ID | 11440 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q61026 | | Bait Uniprot Identifier | NCOA2_MOUSE | | Bait Gene Name | Ncoa2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 745-749 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21440 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482670 | | Comments | Core LXXLL motif sequence (NR Box III) in NCOA2 required for the ligand-dependent binding to the Thyroid hormone receptor |
Record No : 79 |
| Instance ID | 11441 | | Regular Expression | LxxLL | | Motif Instance | LHKLL | | Bait Uniprot Accession | Q9Y6Q9 | | Bait Uniprot Identifier | NCOA3_HUMAN | | Bait Gene Name | NCOA3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 685-689 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | X-ray crystallography; Mutational analysis; Competition binding assay; Mammalian two-hybrid assay | | Interaction ID | 21441 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20086010 | | Comments | Core LXXLL motif sequence (NR Box I) in SRC3/AIB1/NCOA3 required for the ligand-dependent binding to the Androgen receptor(AR) & this functional relationship between AR and SRC3 leads to the development and growth of prostate cancer. |
Record No : 80 |
| Instance ID | 11442 | | Regular Expression | LxxLL | | Motif Instance | LHTLL | | Bait Uniprot Accession | Q9Y6Q9 | | Bait Uniprot Identifier | NCOA3_HUMAN | | Bait Gene Name | NCOA3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1057-1061 | | Critical Residues | P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | X-ray crystallography; Mutational analysis; Competition binding assay; Mammalian two-hybrid assay | | Interaction ID | 21442 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20086010 | | Comments | Core LXXLL motif sequence (NR Box III) in SRC3/AIB1/NCOA3 required for the ligand-dependent binding to the Androgen receptor(AR) & this functional relationship between AR and SRC3 leads to the development and growth of prostate cancer. |
Record No : 81 |
| Instance ID | 11443 | | Regular Expression | LxxLL | | Motif Instance | LHKLL | | Bait Uniprot Accession | Q9Y6Q9 | | Bait Uniprot Identifier | NCOA3_HUMAN | | Bait Gene Name | NCOA3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 685-689 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mammalian two-hybrid assay | | Interaction ID | 21443 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20086010 | | Comments | Core LXXLL motif sequence (NR Box I) in SRC3/AIB1/NCOA3 required for the ligand-dependent binding to the Estrogen receptor(ER-alpha), which may serve as the physical basis for functional coupling of these two proteins for breast cancer development and progression. |
Record No : 82 |
| Instance ID | 11444 | | Regular Expression | LxxLL | | Motif Instance | LRYLL | | Bait Uniprot Accession | Q9Y6Q9 | | Bait Uniprot Identifier | NCOA3_HUMAN | | Bait Gene Name | NCOA3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 738-742 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mammalian two-hybrid assay | | Interaction ID | 21444 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20086010 | | Comments | Core LXXLL motif sequence (NR Box II) in SRC3/AIB1/NCOA3 required for the ligand-dependent binding to the Estrogen receptor(ER-alpha), which may serve as the physical basis for functional coupling of these two proteins for breast cancer development and progression. |
Record No : 83 |
| Instance ID | 11445 | | Regular Expression | LxxLL | | Motif Instance | LTSLL | | Bait Uniprot Accession | Q64127 | | Bait Uniprot Identifier | TIF1A_MOUSE | | Bait Gene Name | Trim24 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 761-765 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21445 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8978696 | | Comments | Core LXXLL motif sequence in TRIM24 required for the ligand-dependent binding to Estrogen receptor |
Record No : 84 |
| Instance ID | 11446 | | Regular Expression | LxxLL | | Motif Instance | LTSLL | | Bait Uniprot Accession | Q64127 | | Bait Uniprot Identifier | TIF1A_MOUSE | | Bait Gene Name | Trim24 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 761-765 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21446 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8978696 | | Comments | Core LXXLL motif sequence in TRIM24 required for the ligand-dependent binding to Retinoic acid receptor |
Record No : 85 |
| Instance ID | 11447 | | Regular Expression | LxxLL | | Motif Instance | LTSLL | | Bait Uniprot Accession | Q64127 | | Bait Uniprot Identifier | TIF1A_MOUSE | | Bait Gene Name | Trim24 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 761-765 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21447 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8978696 | | Comments | Core LXXLL motif sequence in TRIM24 required for the ligand-dependent binding to Vitamin D3 receptor |
Record No : 86 |
| Instance ID | 11448 | | Regular Expression | LxxLL | | Motif Instance | LTSLL | | Bait Uniprot Accession | Q64127 | | Bait Uniprot Identifier | TIF1A_MOUSE | | Bait Gene Name | Trim24 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 761-765 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21448 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8978696 | | Comments | Core LXXLL motif sequence in TRIM24 required for the ligand-dependent binding to Progesterone receptor |
Record No : 87 |
| Instance ID | 11449 | | Regular Expression | LxxLL | | Motif Instance | LTSLL | | Bait Uniprot Accession | Q64127 | | Bait Uniprot Identifier | TIF1A_MOUSE | | Bait Gene Name | Trim24 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 761-765 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21449 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8978696 | | Comments | Core LXXLL motif sequence in TRIM24 required for the ligand-dependent binding to Retinoid X receptor |
Record No : 88 |
| Instance ID | 11450 | | Regular Expression | LxxLL | | Motif Instance | LSELL | | Bait Uniprot Accession | P45481 | | Bait Uniprot Identifier | CBP_MOUSE | | Bait Gene Name | Crebbp | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 69-73 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21450 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8616895, 9192902 | | Comments | Conserved motif on N-terminal of CBP for interaction with the Retinoic acid receptor |
Record No : 89 |
| Instance ID | 11451 | | Regular Expression | LxxLL | | Motif Instance | LSELL | | Bait Uniprot Accession | P45481 | | Bait Uniprot Identifier | CBP_MOUSE | | Bait Gene Name | Crebbp | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 69-73 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21451 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8616895, 9192902 | | Comments | Conserved motif on N-terminal of CBP for interaction with the Thyroid hormone receptor |
Record No : 90 |
| Instance ID | 11452 | | Regular Expression | LxxLL | | Motif Instance | LSELL | | Bait Uniprot Accession | P45481 | | Bait Uniprot Identifier | CBP_MOUSE | | Bait Gene Name | Crebbp | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 69-73 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21452 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8616895, 9192902 | | Comments | Conserved motif on N-terminal of CBP for interaction with the Retinoid X receptor |
Record No : 91 |
| Instance ID | 11453 | | Regular Expression | LxxLL | | Motif Instance | LSELL | | Bait Uniprot Accession | P45481 | | Bait Uniprot Identifier | CBP_MOUSE | | Bait Gene Name | Crebbp | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 69-73 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21453 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8616895, 9192902 | | Comments | Conserved motif on N-terminal of CBP for interaction with the Estrogen receptor |
Record No : 92 |
| Instance ID | 11454 | | Regular Expression | LxxLL | | Motif Instance | LSELL | | Bait Uniprot Accession | P45481 | | Bait Uniprot Identifier | CBP_MOUSE | | Bait Gene Name | Crebbp | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 69-73 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21454 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8616895, 9192902 | | Comments | Conserved motif on N-terminal of CBP for interaction with the Glucocorticoid receptor |
Record No : 93 |
| Instance ID | 11455 | | Regular Expression | LxxLL | | Motif Instance | LVLLL | | Bait Uniprot Accession | P45481 | | Bait Uniprot Identifier | CBP_MOUSE | | Bait Gene Name | Crebbp | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 357-361 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21455 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8616895, 9192902 | | Comments | Conserved motif on CBP for interaction with the Retinoic acid receptor |
Record No : 94 |
| Instance ID | 11456 | | Regular Expression | LxxLL | | Motif Instance | LVLLL | | Bait Uniprot Accession | P45481 | | Bait Uniprot Identifier | CBP_MOUSE | | Bait Gene Name | Crebbp | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 357-361 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21456 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8616895, 9192902 | | Comments | Conserved motif on CBP for interaction with the Thyroid hormone receptor |
Record No : 95 |
| Instance ID | 11457 | | Regular Expression | LxxLL | | Motif Instance | LVLLL | | Bait Uniprot Accession | P45481 | | Bait Uniprot Identifier | CBP_MOUSE | | Bait Gene Name | Crebbp | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 357-361 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21457 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8616895, 9192902 | | Comments | Conserved motif on CBP for interaction with the Retinoid X receptor |
Record No : 96 |
| Instance ID | 11458 | | Regular Expression | LxxLL | | Motif Instance | LVLLL | | Bait Uniprot Accession | P45481 | | Bait Uniprot Identifier | CBP_MOUSE | | Bait Gene Name | Crebbp | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 357-361 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21458 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8616895, 9192902 | | Comments | Conserved motif on CBP for interaction with the the Glucocorticoid receptor |
Record No : 97 |
| Instance ID | 11459 | | Regular Expression | LxxLL | | Motif Instance | LVLLL | | Bait Uniprot Accession | P45481 | | Bait Uniprot Identifier | CBP_MOUSE | | Bait Gene Name | Crebbp | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 357-361 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21459 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8616895, 9192902 | | Comments | Conserved motif on CBP for interaction with the Estrogen receptor |
Record No : 98 |
| Instance ID | 11460 | | Regular Expression | LxxLL | | Motif Instance | LSELL | | Bait Uniprot Accession | B2RWS6 | | Bait Uniprot Identifier | EP300_MOUSE | | Bait Gene Name | Ep300 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 81-85 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21460 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8616895, 9192902 | | Comments | Conserved motif on Ep300 for interaction with the Retinoic acid receptor |
Record No : 99 |
| Instance ID | 11461 | | Regular Expression | LxxLL | | Motif Instance | LSELL | | Bait Uniprot Accession | B2RWS6 | | Bait Uniprot Identifier | EP300_MOUSE | | Bait Gene Name | Ep300 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 81-85 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21461 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8616895, 9192902 | | Comments | Conserved motif on Ep300 for interaction with the the Glucocorticoid receptor |
Record No : 100 |
| Instance ID | 11462 | | Regular Expression | LxxLL | | Motif Instance | LVLLL | | Bait Uniprot Accession | B2RWS6 | | Bait Uniprot Identifier | EP300_MOUSE | | Bait Gene Name | Ep300 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 343-347 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21462 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8616895, 9192902 | | Comments | Conserved motif on Ep300 for interaction with the Retinoic acid receptor |
Record No : 101 |
| Instance ID | 11463 | | Regular Expression | LxxLL | | Motif Instance | LVLLL | | Bait Uniprot Accession | B2RWS6 | | Bait Uniprot Identifier | EP300_MOUSE | | Bait Gene Name | Ep300 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 343-347 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21463 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8616895, 9192902 | | Comments | Conserved motif on Ep300 for interaction with the the Glucocorticoid receptor |
Record No : 102 |
| Instance ID | 11464 | | Regular Expression | FxxLF | | Motif Instance | FQNLF | | Bait Uniprot Accession | P10275 | | Bait Uniprot Identifier | ANDR_HUMAN | | Bait Gene Name | AR | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 23-27 | | Critical Residues | P1; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutational analysis; Mammalian two-hybrid assay; GST interaction assay | | Interaction ID | 21464 | | Interacting Domain | AF-2 transcriptional activation domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10816582 | | Comments | The FXXLF sequence in the N-terminal domain of Androgen receptor(AR), the predominant androgen-dependent interaction site, that interacts with AF2 and mediates a direct interaction between the N-terminal and C-terminal regions of AR to stabilize the hormone-receptor complex for AR-mediated transcriptional activation |
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