Query 'ASH-RhoGAP-like domain' matched 3 Records
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Record No : 1 |
| Instance ID | 11194 | | Regular Expression | xF[^P][^P][KRIL]H[^P][^P][YLMFH][^P]xxx | | Motif Instance | PFARLHECYGQEI | | Bait Uniprot Accession | Q8N4B1 | | Bait Uniprot Identifier | SESQ1_HUMAN | | Bait Gene Name | FAM109A | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 223-235 | | Critical Residues | P2; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation disrupting interaction; X-ray crystallography; ITC; SPR; Y2H; Co-IP; Pull down(GST tag); Colocalization; Competition binding | | Interaction ID | 21194 | | Interacting Domain | ASH-RhoGAP-like domain | | Disease Association(s) | Lowe syndrome; Dent disease type 2 | | Inhibitor(s) | Unknown | | Reference(s) | 21233288, 20133602, 21666675 | | Comments | The conserved F and H motif in human Sesquipedalian-1 (FAM109A/IPIP27A) that binds to the ASH-RhoGAP-like domain of human OCRL1 |
Record No : 2 |
| Instance ID | 11195 | | Regular Expression | xF[^P][^P][KRIL]H[^P][^P][YLMFH][^P]xxx | | Motif Instance | CFSTLHDWYGQEI | | Bait Uniprot Accession | Q6ICB4 | | Bait Uniprot Identifier | SESQ2_HUMAN | | Bait Gene Name | FAM109B | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 223-235 | | Critical Residues | P2; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation disrupting interaction; Y2H; Co-IP; Pull down(GST tag); ITC; SPR; Colocalization; Competition binding | | Interaction ID | 21195 | | Interacting Domain | ASH-RhoGAP-like domain | | Disease Association(s) | Lowe syndrome; Dent disease type 2 | | Inhibitor(s) | Unknown | | Reference(s) | 21233288, 20133602, 21666675 | | Comments | The conserved F and H motif in human Sesquipedalian-2 (FAM109B/IPIP27B) that binds to the ASH-RhoGAP-like domain of human OCRL1 |
Record No : 3 |
| Instance ID | 11196 | | Regular Expression | xF[^P][^P][KRIL]H[^P][^P][YLMFH][^P]xxx | | Motif Instance | SFQQRHESLRPAA | | Bait Uniprot Accession | Q9UKG1 | | Bait Uniprot Identifier | DP13A_HUMAN | | Bait Gene Name | APPL1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 403-415 | | Critical Residues | P2; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation disrupting interaction; Sequence based prediction; Co-IP; Pull down(GST tag); ITC; SPR; Colocalization; Competition binding | | Interaction ID | 21196 | | Interacting Domain | ASH-RhoGAP-like domain | | Disease Association(s) | Lowe syndrome | | Inhibitor(s) | Unknown | | Reference(s) | 21233288, 18307981, 17765681, 20133602, 21666675 | | Comments | The conserved F and H motif in human DCC-interacting protein 13-alpha (DIP13A/APPL1) that binds to the ASH-RhoGAP-like domain of human OCRL1 |
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