Query 'Ankyrin repeat domain' matched 27 Records
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Record No : 1 |
| Instance ID | 10994 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | QRSPPDGQ | | Bait Uniprot Accession | P78314 | | Bait Uniprot Identifier | 3BP2_HUMAN | | Bait Gene Name | SH3BP2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 414-421 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Fluorescence polarization spectroscopy; Alanine scanning; Pull down; Co-IP | | Interaction ID | 20994 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Cherubism | | Inhibitor(s) | Unknown | | Reference(s) | 22153077 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human SH3 domain-binding protein 2 (SH3BP2) |
Record No : 2 |
| Instance ID | 10995 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | SRSEGEGE | | Bait Uniprot Accession | Q9NWV8 | | Bait Uniprot Identifier | BABA1_HUMAN | | Bait Gene Name | BABAM1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 47-54 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Fluorescence polarization spectroscopy; Mutation analysis; Co-IP | | Interaction ID | 20995 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22153077 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif (47-54) in human MERIT40/BABAM1 |
Record No : 3 |
| Instance ID | 10996 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | PRGCADGR | | Bait Uniprot Accession | P54274 | | Bait Uniprot Identifier | TERF1_HUMAN | | Bait Gene Name | TERF1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 12-19 | | Critical Residues | P7 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down(GST tag); Alanine scanning; X-ray crystallography | | Interaction ID | 20996 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12080061, 22153077 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human Telomeric repeat-binding factor 1 (TERF1) |
Record No : 4 |
| Instance ID | 10997 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | TRNPADGI | | Bait Uniprot Accession | Q6V0I7 | | Bait Uniprot Identifier | FAT4_HUMAN | | Bait Gene Name | FAT4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 4826-4833 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Fluorescence polarization spectroscopy; Mutation analysis; Co-IP | | Interaction ID | 20997 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22153077 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human Protocadherin FAT4 |
Record No : 5 |
| Instance ID | 10998 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | IRPPPDGS | | Bait Uniprot Accession | Q92698 | | Bait Uniprot Identifier | RAD54_HUMAN | | Bait Gene Name | RAD54L | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 690-697 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Fluorescence polarization spectroscopy; Mutation analysis; Co-IP | | Interaction ID | 20998 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22153077 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human DNA repair and recombination protein RAD54L |
Record No : 6 |
| Instance ID | 10999 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | ARPDGEGS | | Bait Uniprot Accession | A9UF02 | | Bait Uniprot Identifier | A9UF02_HUMAN | | Bait Gene Name | BCR/ABL fusion | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 115-122 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Fluorescence polarization spectroscopy; Mutation analysis; Co-IP | | Interaction ID | 20999 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22153077 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human BCR/ABL fusion protein isoform X9 |
Record No : 7 |
| Instance ID | 11000 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | PRTQPDGT | | Bait Uniprot Accession | Q14980 | | Bait Uniprot Identifier | NUMA1_HUMAN | | Bait Gene Name | NUMA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1742-1749 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Affinity chromatography technology; X-ray crystallography | | Interaction ID | 21000 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12080061, 22153077 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human Nuclear mitotic apparatus protein 1 (NUMA1) |
Record No : 8 |
| Instance ID | 11001 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | TRSNPEGA | | Bait Uniprot Accession | Q9NWV8 | | Bait Uniprot Identifier | BABA1_HUMAN | | Bait Gene Name | BABAM1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 27-34 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Fluorescence polarization spectroscopy; Mutation analysis; Co-IP | | Interaction ID | 21001 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22153077 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif (27-34) in human MERIT40/BABAM1 |
Record No : 9 |
| Instance ID | 11002 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | ARPPPIGA | | Bait Uniprot Accession | Q07820 | | Bait Uniprot Identifier | MCL1_HUMAN | | Bait Gene Name | MCL1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 77-84 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | X-ray crystallography | | Interaction ID | 21002 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22153077 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human Induced myeloid leukemia cell differentiation protein MCL1 |
Record No : 10 |
| Instance ID | 11003 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | YRQSPDGA | | Bait Uniprot Accession | Q9UIQ6 | | Bait Uniprot Identifier | LCAP_HUMAN | | Bait Gene Name | LNPEP | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 95-102 | | Critical Residues | P2; P5; P6; P7 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down(GST tag); Alanine scanning; X-ray crystallography | | Interaction ID | 21003 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12080061, 22153077 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human Leucyl-cystinyl aminopeptidase (LNPEP) |
Record No : 11 |
| Instance ID | 11004 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | DRESPDGS | | Bait Uniprot Accession | Q96RU3 | | Bait Uniprot Identifier | FNBP1_HUMAN | | Bait Gene Name | FNBP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 514-521 | | Critical Residues | P2; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | X-ray crystallography; Y2H; Mutation analysis; Co-IP | | Interaction ID | 21004 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22153077, 14596906 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human Formin-binding protein 1 (FNBP1) |
Record No : 12 |
| Instance ID | 11005 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | PRPPVPGE | | Bait Uniprot Accession | O15169 | | Bait Uniprot Identifier | AXIN1_HUMAN | | Bait Gene Name | AXIN1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 21-28 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Pull down; Fluorescence polarization spectroscopy; Alanine scanning | | Interaction ID | 21005 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 19759537, 22153077 | | Comments | The ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-1 (TNKS) interacts with the Tankyrase-binding motif in human AXIN1 |
Record No : 13 |
| Instance ID | 11006 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | PRPPVPGE | | Bait Uniprot Accession | O15169 | | Bait Uniprot Identifier | AXIN1_HUMAN | | Bait Gene Name | AXIN1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 21-28 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Pull down; Fluorescence polarization spectroscopy; Alanine scanning | | Interaction ID | 21006 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 19759537, 22153077 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human AXIN1 |
Record No : 14 |
| Instance ID | 11007 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | WRPQPDGE | | Bait Uniprot Accession | Q9C0C2 | | Bait Uniprot Identifier | TB182_HUMAN | | Bait Gene Name | TNKS1BP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1507-1514 | | Critical Residues | P7 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Alanine scanning; Pull down(GST tag) | | Interaction ID | 21007 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12080061 | | Comments | The ANK subdomain V in human poly(ADP-ribose)polymerase Tankyrase-1 (TNKS) interacts with the Tankyrase-binding motif in human TAB182 (182-kDa tankyrase-binding protein) |
Record No : 15 |
| Instance ID | 11008 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | WRPQPDGE | | Bait Uniprot Accession | Q9C0C2 | | Bait Uniprot Identifier | TB182_HUMAN | | Bait Gene Name | TNKS1BP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1507-1514 | | Critical Residues | P7 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Alanine scanning; Pull down(GST tag) | | Interaction ID | 21008 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12080061 | | Comments | The ANK subdomain V in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human TAB182 (182-kDa tankyrase-binding protein) |
Record No : 16 |
| Instance ID | 11009 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | ERGEAEGC | | Bait Uniprot Accession | Q9NRI5 | | Bait Uniprot Identifier | DISC1_HUMAN | | Bait Gene Name | DISC1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 222-229 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Fluorescence polarization spectroscopy; Mutation analysis; Co-IP | | Interaction ID | 21009 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22153077 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human Disrupted in schizophrenia 1 protein (DISC1) |
Record No : 17 |
| Instance ID | 11010 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | SRSAGDGT | | Bait Uniprot Accession | O43815 | | Bait Uniprot Identifier | STRN_HUMAN | | Bait Gene Name | STRN | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 301-308 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Fluorescence polarization spectroscopy; Mutation analysis; Co-IP | | Interaction ID | 21010 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22153077 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human Striatin (STRN) |
Record No : 18 |
| Instance ID | 11011 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | VRKQPEGN | | Bait Uniprot Accession | Q6V0I7 | | Bait Uniprot Identifier | FAT4_HUMAN | | Bait Gene Name | FAT4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 4571-4578 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Fluorescence polarization spectroscopy; Mutation analysis; Co-IP | | Interaction ID | 21011 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22153077 | | Comments | The N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human Protocadherin FAT4 |
Record No : 19 |
| Instance ID | 11012 | | Regular Expression | xRxx[PGAV][DEIP]Gx | | Motif Instance | ERQSGDGQ | | Bait Uniprot Accession | O15234 | | Bait Uniprot Identifier | CASC3_HUMAN | | Bait Gene Name | CASC3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 145-152 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Co-IP | | Interaction ID | 21012 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 21478859 | | Comments | The Tankyrase-binding motif of human Cancer susceptibility candidate gene 3 protein (CASC3) that mediates its interaction with human ADP-ribosyltransferase Tankyrase-1 (TNKS) |
Record No : 20 |
| Instance ID | 11955 | | Regular Expression | PxLPx[IL] | | Motif Instance | PSLPNI | | Bait Uniprot Accession | P56524 | | Bait Uniprot Identifier | HDAC4_HUMAN | | Bait Gene Name | HDAC4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 349-354 | | Critical Residues | P1; P3; P4; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | X-ray crystallography; Peptide array binding assay; Mutational analysis; ITC | | Interaction ID | 21955 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22649097, 15964851 | | Comments | The PxLPxI/L motif of human Histone deacetylase 4 recognized by Ankyrin repeat family A protein 2 (ANKRA2) for signal-dependent binding to the ankyrin repeat domain |
Record No : 21 |
| Instance ID | 11956 | | Regular Expression | PxLPx[IL] | | Motif Instance | PSLPNI | | Bait Uniprot Accession | Q9UQL6 | | Bait Uniprot Identifier | HDAC5_HUMAN | | Bait Gene Name | HDAC5 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 367-372 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21956 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22649097, 15964851 | | Comments | The PxLPxI/L motif of human Histone deacetylase 5 recognized by Ankyrin repeat family A protein 2 (ANKRA2) for signal-dependent binding to the ankyrin repeat domain |
Record No : 22 |
| Instance ID | 11957 | | Regular Expression | PxLPx[IL] | | Motif Instance | PTLPKL | | Bait Uniprot Accession | P98164 | | Bait Uniprot Identifier | LRP2_HUMAN | | Bait Gene Name | LRP2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 4458-4463 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | ITC; Y2H; Pull down(GST tag) | | Interaction ID | 21957 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22649097, 11095640 | | Comments | The PxLPxI/L motif (4458-4463) of human Low-density lipoprotein receptor-related protein 2 (Megalin) recognized by Ankyrin repeat family A protein 2 (ANKRA2) for binding to the ankyrin repeat domain |
Record No : 23 |
| Instance ID | 11958 | | Regular Expression | PxLPx[IL] | | Motif Instance | PKLPSL | | Bait Uniprot Accession | P98164 | | Bait Uniprot Identifier | LRP2_HUMAN | | Bait Gene Name | LRP2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 4461-4466 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | ITC; Y2H; Pull down(GST tag) | | Interaction ID | 21958 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22649097, 11095640 | | Comments | The PxLPxI/L motif (4461-4466) of human Low-density lipoprotein receptor-related protein 2 (Megalin) recognized by Ankyrin repeat family A protein 2 (ANKRA2) for binding to the ankyrin repeat domain |
Record No : 24 |
| Instance ID | 11959 | | Regular Expression | PxLPx[IL] | | Motif Instance | PPLPGL | | Bait Uniprot Accession | P48382 | | Bait Uniprot Identifier | RFX5_HUMAN | | Bait Gene Name | RFX5 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 173-178 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | ITC | | Interaction ID | 21959 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22649097 | | Comments | The PxLPxI/L motif of human DNA-binding protein RFX5 recognized by Ankyrin repeat family A protein 2 (ANKRA2) for binding to the ankyrin repeat domain |
Record No : 25 |
| Instance ID | 11960 | | Regular Expression | PxLPx[IL] | | Motif Instance | PSLPNI | | Bait Uniprot Accession | P56524 | | Bait Uniprot Identifier | HDAC4_HUMAN | | Bait Gene Name | HDAC4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 349-354 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutational analysis; ITC | | Interaction ID | 21960 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22649097, 15964851 | | Comments | The PxLPxI/L motif of human Histone deacetylase 4 recognized by Regulatory factor X-associated ankyrin-containing protein (RFXANK, also known as ANKRA1 and RFX-B) for binding to the ankyrin repeat domain |
Record No : 26 |
| Instance ID | 11961 | | Regular Expression | PxLPx[IL] | | Motif Instance | PSLPNI | | Bait Uniprot Accession | Q9UQL6 | | Bait Uniprot Identifier | HDAC5_HUMAN | | Bait Gene Name | HDAC5 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 367-372 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21961 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22649097, 15964851 | | Comments | The PxLPxI/L motif of human Histone deacetylase 5 recognized by Regulatory factor X-associated ankyrin-containing protein (RFXANK, also known as ANKRA1 and RFX-B) for binding to the ankyrin repeat domain |
Record No : 27 |
| Instance ID | 11962 | | Regular Expression | PxLPx[IL] | | Motif Instance | PPLPGL | | Bait Uniprot Accession | P48382 | | Bait Uniprot Identifier | RFX5_HUMAN | | Bait Gene Name | RFX5 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 173-178 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | X-ray crystallography; ITC | | Interaction ID | 21962 | | Interacting Domain | Ankyrin repeat domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22649097 | | Comments | The PxLPxI/L motif of human DNA-binding protein RFX5 recognized by Regulatory factor X-associated ankyrin-containing protein (RFXANK, also known as ANKRA1 and RFX-B) for binding to the ankyrin repeat domain |
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