Query   'CB3 region'  matched   4 Records

Record No : 1

Instance ID11786
Regular Expression[AET]xYLxxLN
Motif InstanceARYLQKLN
Bait Uniprot AccessionQ19KW5
Bait Uniprot IdentifierQ19KW5_STREQ
Bait Gene Nameemm
Bait OrganismStreptococcus dysgalactiae subsp. equisimilis (Streptococcus equisimilis)
Sequence Position81-88
Critical ResiduesP1; P3; P4; P7
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Site-directed mutagenesis; SPR; Peptide binding assay
Interaction ID21786
Interacting DomainCB3 region
Disease Association(s)Rheumatic fever
Inhibitor(s)Unknown
Reference(s)17452321, 19520603
CommentsThe octapeptide collagen-binding motif known as “Peptide Associated with Rheumatic Fever” (PARF) in the M protein of Streptococcus dysgalactiae subsp. equisimilis that helps to bind the CB3-region of human Collagen alpha-4(IV) chain

Record No : 2

Instance ID11787
Regular Expression[AET]xYLxxLN
Motif InstanceAWYLKELN
Bait Uniprot AccessionO85813
Bait Uniprot IdentifierO85813_STRSG
Bait Gene Nameemm
Bait OrganismStreptococcus sp. group G
Sequence Position83-90
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)SPR
Interaction ID21787
Interacting DomainCB3 region
Disease Association(s)Rheumatic fever
Inhibitor(s)Unknown
Reference(s)19520603
CommentsThe octapeptide collagen-binding motif known as “Peptide Associated with Rheumatic Fever” (PARF) in the M protein of Streptococcus sp. group G that helps to bind the CB3-region of human Collagen alpha-4(IV) chain

Record No : 3

Instance ID11788
Regular Expression[AET]xYLxxLN
Motif InstanceTQYLKRLN
Bait Uniprot AccessionQ1KQ03
Bait Uniprot IdentifierQ1KQ03_STREQ
Bait Gene Nameemm
Bait OrganismStreptococcus dysgalactiae subsp. equisimilis (Streptococcus equisimilis)
Sequence Position79-86
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)SPR
Interaction ID21788
Interacting DomainCB3 region
Disease Association(s)Rheumatic fever
Inhibitor(s)Unknown
Reference(s)19520603
CommentsThe octapeptide collagen-binding motif known as “Peptide Associated with Rheumatic Fever” (PARF) in the M protein of Streptococcus dysgalactiae subsp. equisimilis that helps to bind the CB3-region of human Collagen alpha-4(IV) chain

Record No : 4

Instance ID11789
Regular Expression[AET]xYLxxLN
Motif InstanceAEYLKGLN
Bait Uniprot AccessionQ54835
Bait Uniprot IdentifierQ54835_STRPY
Bait Gene Nameemm3
Bait OrganismStreptococcus pyogenes
Sequence Position94-101
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)SPR
Interaction ID21789
Interacting DomainCB3 region
Disease Association(s)Rheumatic fever
Inhibitor(s)Unknown
Reference(s)19520603
CommentsThe octapeptide collagen-binding motif known as “Peptide Associated with Rheumatic Fever” (PARF) in the M3 protein of Streptococcus pyogenes that helps to bind the CB3-region of human Collagen alpha-4(IV) chain


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)