Query   'Clathrin propeller repeat'  matched   12 Records

Record No : 1

Instance ID10229
Regular ExpressionL[IVLMF]x[IVLMF][DE]
Motif InstanceLLGLD
Bait Uniprot AccessionQ91VZ6
Bait Uniprot IdentifierSMAP1_MOUSE
Bait Gene NameSmap1
Bait OrganismMus musculus (Mouse)
Sequence Position192-196
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Pull down; Mutation analysis; Alanine scanning
Interaction ID20229
Interacting DomainClathrin propeller repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15659652
CommentsClathrin-box-like sequence in the mouse Smap1 protein that interact with the N-terminal beta-propeller structure of Clathrin heavy chain

Record No : 2

Instance ID10230
Regular ExpressionL[IVLMF]x[IVLMF][DE]
Motif InstanceLLGLE
Bait Uniprot AccessionQ27974
Bait Uniprot IdentifierAUXI_BOVIN
Bait Gene NameDNAJC6
Bait OrganismBos taurus (Bovine)
Sequence Position496-500
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Peptide competition assay; Fluorescence polarization spectroscopy
Interaction ID20230
Interacting DomainClathrin propeller repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)14757058
CommentsClathrin box motif in bovine auxilin (DNAJC6) that is sufficient for binding to the amino terminal beta propeller structure of Clathrin heavy chain

Record No : 3

Instance ID10231
Regular ExpressionL[IVLMF]x[IVLMF][DE]
Motif InstanceLLDLD
Bait Uniprot AccessionO00499
Bait Uniprot IdentifierBIN1_HUMAN
Bait Gene NameBIN1
Bait OrganismHomo sapiens (Human)
Sequence Position390-394
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutation analysis; Pull down; Western blot
Interaction ID20231
Interacting DomainClathrin propeller repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9603201
CommentsClathrin box motif in human Amphiphysin II (BIN1) that is sufficient for binding to the amino terminal beta propeller structure of Clathrin heavy chain

Record No : 4

Instance ID10232
Regular ExpressionL[IVLMF]x[IVLMF][DE]
Motif InstanceLLDLD
Bait Uniprot AccessionP49418
Bait Uniprot IdentifierAMPH_HUMAN
Bait Gene NameAMPH
Bait OrganismHomo sapiens (Human)
Sequence Position351-355
Critical ResiduesP3; P4; P5
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Pull down; Mutation analysis
Interaction ID20232
Interacting DomainClathrin propeller repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10748223
CommentsClathrin box motif in human Amphiphysin (AMPH) that is sufficient for binding to the amino terminal beta propeller structure of Clathrin heavy chain

Record No : 5

Instance ID10233
Regular ExpressionL[IVLMF]x[IVLMF][DE]
Motif InstanceLLDLE
Bait Uniprot AccessionQ13367
Bait Uniprot IdentifierAP3B2_HUMAN
Bait Gene NameAP3B2
Bait OrganismHomo sapiens (Human)
Sequence Position808-812
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Western blot; Confocal microscopy; Classical fluorescence spectroscopy; Pull down
Interaction ID20233
Interacting DomainClathrin propeller repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9545220
CommentsClathrin box motif in human AP-3 complex subunit beta-2 that is sufficient for binding to the amino terminal beta propeller structure of Clathrin heavy chain

Record No : 6

Instance ID10234
Regular ExpressionL[IVLMF]x[IVLMF][DE]
Motif InstanceLIEFD
Bait Uniprot AccessionQ91YI4
Bait Uniprot IdentifierARRB2_MOUSE
Bait Gene NameArrb2
Bait OrganismMus musculus (Mouse)
Sequence Position374-378
Critical ResiduesP1; P2; P3; P4; P5
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Alanine scanning; Mutation analysis; Pull down
Interaction ID20234
Interacting DomainClathrin propeller repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9169476
CommentsClathrin box motif in the mouse Arrestin beta-2 that interact with the N-terminal beta-propeller structure of Clathrin heavy chain

Record No : 7

Instance ID10235
Regular ExpressionL[IVLMF]x[IVLMF][DE]
Motif InstanceLLDLD
Bait Uniprot AccessionO00203
Bait Uniprot IdentifierAP3B1_HUMAN
Bait Gene NameAP3B1
Bait OrganismHomo sapiens (Human)
Sequence Position818-822
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)X-ray crystallography
Interaction ID20235
Interacting DomainClathrin propeller repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10655490
CommentsClathrin box motif in human AP-3 complex subunit beta-1 that is sufficient for binding to the amino terminal beta propeller structure of Clathrin heavy chain

Record No : 8

Instance ID10236
Regular ExpressionL[IVLMF]x[IVLMF][DE]
Motif InstanceLIEFE
Bait Uniprot AccessionP32120
Bait Uniprot IdentifierARRB2_BOVIN
Bait Gene NameARRB2
Bait OrganismBos taurus (Bovine)
Sequence Position384-388
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Peptide binding to perpetrator; X-ray crystallography
Interaction ID20236
Interacting DomainClathrin propeller repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10655490
CommentsClathrin box motif in the bovine Arrestin beta-2 that interact with the N-terminal beta-propeller structure of Clathrin heavy chain

Record No : 9

Instance ID10237
Regular ExpressionL[IVLMF]x[IVLMF][DE]
Motif InstanceLMDMD
Bait Uniprot AccessionO00291
Bait Uniprot IdentifierHIP1_HUMAN
Bait Gene NameHIP1
Bait OrganismHomo sapiens (Human)
Sequence Position332-336
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Pull down; Classical fluorescence spectroscopy; Confocal microscopy
Interaction ID20237
Interacting DomainClathrin propeller repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11577110, 11517213
CommentsClathrin box motif in human Huntingtin-interacting protein 1 that is sufficient for binding to the amino terminal beta propeller structure of Clathrin heavy chain

Record No : 10

Instance ID10238
Regular ExpressionL[IVLMF]x[IVLMF][DE]
Motif InstanceLIDLE
Bait Uniprot AccessionQ9UJY4
Bait Uniprot IdentifierGGA2_HUMAN
Bait Gene NameGGA2
Bait OrganismHomo sapiens (Human)
Sequence Position349-353
Critical ResiduesP1; P2; P4; P5
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Pull down; Mutation analysis; Electron microscopy
Interaction ID20238
Interacting DomainClathrin propeller repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11301005
CommentsClathrin box motif in human ADP-ribosylation factor-binding protein GGA2 that is sufficient for binding to the amino terminal beta propeller structure of Clathrin heavy chain

Record No : 11

Instance ID10239
Regular Expressionx[NP]W[DES]xW
Motif InstanceLPWDLW
Bait Uniprot AccessionP49418
Bait Uniprot IdentifierAMPH_HUMAN
Bait Gene NameAMPH
Bait OrganismHomo sapiens (Human)
Sequence Position380-385
Critical ResiduesP3; P4
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Pull down; Western blot; Mutation analysis; X-ray crystallography; Classical fluorescence spectroscopy
Interaction ID20239
Interacting DomainClathrin propeller repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11382783, 14981508, 10748223
Comments"Variant clathrin box motif (W box) in human Amphiphysin that are found in tandem arrangement with a ""classical"" clathrin box and cooperate to effect optimal clathrin binding and the formation of sedimentable assemblies"

Record No : 12

Instance ID10240
Regular Expressionx[NP]W[DES]xW
Motif InstanceIPWDLW
Bait Uniprot AccessionO00499
Bait Uniprot IdentifierBIN1_HUMAN
Bait Gene NameBIN1
Bait OrganismHomo sapiens (Human)
Sequence Position415-420
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutation analysis; Western blot; Pull down
Interaction ID20240
Interacting DomainClathrin propeller repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9603201
Comments"Variant clathrin box motif (W box) in human Amphiphysin II (BIN1) that are found in tandem arrangement with a ""classical"" clathrin box and cooperate to effect optimal clathrin binding and the formation of sedimentable assemblies"


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)