Query 'D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain' matched 26 Records
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Record No : 1 |
| Instance ID | 10259 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PPDLS | | Bait Uniprot Accession | P17789 | | Bait Uniprot Identifier | TTKB_DROME | | Bait Gene Name | ttk | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 593-597 | | Critical Residues | P1; P2; P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Alanine scanning | | Interaction ID | 20259 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10978285 | | Comments | The PxDLS CtBP ligand motif in Drosophila repressor protein Tramtrack p69 (Ttk69) that is critical for mediating interaction with the Drosophila homolog of C-terminal-binding protein (dCtBP) and essential for Ttk69 function |
Record No : 2 |
| Instance ID | 10260 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | GLDLSK | | Bait Uniprot Accession | Q14526 | | Bait Uniprot Identifier | HIC1_HUMAN | | Bait Gene Name | HIC1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 241-246 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20260 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12052894 | | Comments | The human candidate tumor suppressor gene HIC1 recruits CtBP through a conserved GLDLSKK/R motif highly related to the consensus CtBP interaction motif (PXDLSXK/R), except for the replacement of the virtually invariant proline by a glycine |
Record No : 3 |
| Instance ID | 10261 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PVDLS | | Bait Uniprot Accession | O95600 | | Bait Uniprot Identifier | KLF8_HUMAN | | Bait Gene Name | KLF8 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 86-90 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20261 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10756197 | | Comments | Human Krüppel-like factor 8 contains a Pro-Val-Asp-Leu-Ser/Thr motif that mediates contact with the co-repressor protein C-terminal Binding Protein (CtBP) and represses transcription |
Record No : 4 |
| Instance ID | 10262 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLDLS | | Bait Uniprot Accession | Q99708 | | Bait Uniprot Identifier | COM1_HUMAN | | Bait Gene Name | RBBP8 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 490-494 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Competition binding | | Interaction ID | 20262 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | E1A exon 2 peptide | | Reference(s) | 9535825 | | Comments | Human CtBP was found to specifically interact with human CtIP (CtBP-interacting protein) or DNA endonuclease RBBP8 through a conserved PLDLS motif and the CtBP-CtIP complex is disrupted by E1A resulting in tumorigenesis-restraining activity |
Record No : 5 |
| Instance ID | 10263 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLDLS | | Bait Uniprot Accession | Q64318 | | Bait Uniprot Identifier | ZEB1_MOUSE | | Bait Gene Name | Zeb1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 712-716 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 20263 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10567582 | | Comments | The PxDLS motif in mouse zinc finger-homeodomain factor Delta EF1 that serve as the site for interaction with mouse CtBP1 |
Record No : 6 |
| Instance ID | 10264 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLDLS | | Bait Uniprot Accession | Q64318 | | Bait Uniprot Identifier | ZEB1_MOUSE | | Bait Gene Name | Zeb1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 712-716 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 20264 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10567582 | | Comments | The PxDLS motif in mouse zinc finger-homeodomain factor Delta EF1 that serve as the site for interaction with mouse CtBP2 |
Record No : 7 |
| Instance ID | 10265 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PMDLS | | Bait Uniprot Accession | P10734 | | Bait Uniprot Identifier | KNIR_DROME | | Bait Gene Name | kni | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 331-335 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20265 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9843507 | | Comments | Drosophila CtBP interacts with Zygotic gap protein knirps through the PxDLS motif is essential for the repression activity of this protein in transgenic embryos |
Record No : 8 |
| Instance ID | 10266 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PIDLS | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 440-444 | | Critical Residues | P1; P2; P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20266 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11509661 | | Comments | The PxDLS motif in human Nuclear factor RIP140 that serves as the site for interaction with the transcriptional corepressor CtBP |
Record No : 9 |
| Instance ID | 10267 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLNLS | | Bait Uniprot Accession | P35712 | | Bait Uniprot Identifier | SOX6_HUMAN | | Bait Gene Name | SOX6 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 424-428 | | Critical Residues | P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 20267 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11504872 | | Comments | The PxDLS motif in human transcription factor SOX-6 that serves as the site for interaction with the transcriptional corepressor CtBP |
Record No : 10 |
| Instance ID | 10268 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLDLS | | Bait Uniprot Accession | Q15583 | | Bait Uniprot Identifier | TGIF1_HUMAN | | Bait Gene Name | TGIF1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 153-157 | | Critical Residues | P1; P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Alanine scanning | | Interaction ID | 20268 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Holoprosencephaly | | Inhibitor(s) | Unknown | | Reference(s) | 10995736 | | Comments | The homeodomain protein TGIF1 interacts with the transcriptional corepressor CtBP via the PxDLS motif |
Record No : 11 |
| Instance ID | 10269 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PIDLR | | Bait Uniprot Accession | Q91647 | | Bait Uniprot Identifier | Q91647_XENLA | | Bait Gene Name | cbx4 | | Bait Organism | Xenopus laevis (African clawed frog) | | Sequence Position | 455-459 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 20269 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9858600 | | Comments | Xenopus homolog of C-terminal binding protein 1 (XCtBP1) interacts with Xenopus Pc (XPc), homolog of the Drosophila PcG protein Pc, through the PxDLS motif |
Record No : 12 |
| Instance ID | 10270 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLDLT | | Bait Uniprot Accession | Q96JN0 | | Bait Uniprot Identifier | LCOR_HUMAN | | Bait Gene Name | LCOR | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 64-68 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20270 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12535528 | | Comments | Ligand-dependent nuclear receptor corepressor LCoR interacts with the transcriptional corepressor CtBP via the PxDLS motif |
Record No : 13 |
| Instance ID | 10271 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PIDLR | | Bait Uniprot Accession | O00257 | | Bait Uniprot Identifier | CBX4_HUMAN | | Bait Gene Name | CBX4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 472-476 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20271 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9858600 | | Comments | The C-terminal fragment of human Pc 2 (HPC2), homolog of the Drosophila PcG protein Pc, to which human CtBP2 binds |
Record No : 14 |
| Instance ID | 10272 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLDLA | | Bait Uniprot Accession | Q9UHF7 | | Bait Uniprot Identifier | TRPS1_HUMAN | | Bait Gene Name | TRPS1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1163-1167 | | Critical Residues | P1; P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20272 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12444977 | | Comments | Ikaros-related protein TRPS1 contains a PXDLS CtBP contact motif within its repression domain for binding to murine CtBP2 |
Record No : 15 |
| Instance ID | 10273 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLSLT | | Bait Uniprot Accession | P70062 | | Bait Uniprot Identifier | T7L1A_XENLA | | Bait Gene Name | tcf7l1-a | | Bait Organism | Xenopus laevis (African clawed frog) | | Sequence Position | 469-473 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 20273 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10375506 | | Comments | Xenopus homolog of C-terminal binding protein 1 (XCtBP1) interacts with Xenopus HMG box transcription factor TCF-3-A through the carboxy-terminal PxDLS motif (469-473) |
Record No : 16 |
| Instance ID | 10274 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLSLV | | Bait Uniprot Accession | P70062 | | Bait Uniprot Identifier | T7L1A_XENLA | | Bait Gene Name | tcf7l1-a | | Bait Organism | Xenopus laevis (African clawed frog) | | Sequence Position | 545-549 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 20274 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10375506 | | Comments | Xenopus homolog of C-terminal binding protein 1 (XCtBP1) interacts with Xenopus HMG box transcription factor TCF-3-A through the carboxy-terminal PxDLS motif (545-549) |
Record No : 17 |
| Instance ID | 10275 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLDLS | | Bait Uniprot Accession | O60315 | | Bait Uniprot Identifier | ZEB2_HUMAN | | Bait Gene Name | ZEB2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 815-819 | | Critical Residues | P1; P2; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Alanine scanning | | Interaction ID | 20275 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12714599 | | Comments | Interaction between human Smad-interacting protein-1 (ZEB2) and the corepressor C-terminal binding protein (CTBP1) through conserved PXDLS-like motif (815-819) |
Record No : 18 |
| Instance ID | 10276 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLNLS | | Bait Uniprot Accession | O60315 | | Bait Uniprot Identifier | ZEB2_HUMAN | | Bait Gene Name | ZEB2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 785-789 | | Critical Residues | P1; P2; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Alanine scanning | | Interaction ID | 20276 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12714599 | | Comments | Interaction between human Smad-interacting protein-1 (ZEB2) and the corepressor C-terminal binding protein (CTBP1) through conserved PXDLS-like motif (785-789) |
Record No : 19 |
| Instance ID | 10277 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLNLT | | Bait Uniprot Accession | O60315 | | Bait Uniprot Identifier | ZEB2_HUMAN | | Bait Gene Name | ZEB2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 859-863 | | Critical Residues | P1; P2; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Alanine scanning | | Interaction ID | 20277 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12714599 | | Comments | Interaction between human Smad-interacting protein-1 (ZEB2) and the corepressor C-terminal binding protein (CTBP1) through conserved PXDLS-like motif (859-863) |
Record No : 20 |
| Instance ID | 10278 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PEDLA | | Bait Uniprot Accession | Q9H2S9 | | Bait Uniprot Identifier | IKZF4_HUMAN | | Bait Gene Name | IKZF4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 425-429 | | Critical Residues | P1; P2; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 20278 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12444977 | | Comments | Ikaros family zinc finger protein Eos contains a PXDLS CtBP contact motif within its repression domain for binding to murine CtBP2 |
Record No : 21 |
| Instance ID | 10279 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLDLS | | Bait Uniprot Accession | Q03112 | | Bait Uniprot Identifier | EVI1_HUMAN | | Bait Gene Name | MECOM | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 584-588 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Alanine scanning | | Interaction ID | 20279 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Chronic myeloid leukemia | | Inhibitor(s) | Unknown | | Reference(s) | 11965542 | | Comments | The t(3;21) fusion product, AML1/Evi-1 blocks AML1-induced transactivation by recruiting CtBP through the PxDLS motif |
Record No : 22 |
| Instance ID | 10280 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLDLS | | Bait Uniprot Accession | P28166 | | Bait Uniprot Identifier | ZFH1_DROME | | Bait Gene Name | zfh1 | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 786-790 | | Critical Residues | P1; P2; P3; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 20280 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10359772 | | Comments | Drosophila Zinc finger protein 1 (zfh-1), homologue of active transcriptional repressor ZEB, interacts with the corepressor CtBP to repress transcription through the PxDLS motif |
Record No : 23 |
| Instance ID | 10281 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLSLV | | Bait Uniprot Accession | P14003 | | Bait Uniprot Identifier | HAIR_DROME | | Bait Gene Name | h | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 318-322 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20281 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9524128 | | Comments | Drosophila CtBP interacts specifically and directly with a C-terminal PxDLS motif of the transcriptional repressor hairy (h) |
Record No : 24 |
| Instance ID | 10282 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLNLS | | Bait Uniprot Accession | P41970 | | Bait Uniprot Identifier | ELK3_HUMAN | | Bait Gene Name | ELK3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 273-277 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20282 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10369679 | | Comments | mCtBP1 interacts strongly with Net, a negative Ras-switchable ternary complex factor, through its CtBP interaction domain (CID) |
Record No : 25 |
| Instance ID | 10283 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PEDLS | | Bait Uniprot Accession | Q13422 | | Bait Uniprot Identifier | IKZF1_HUMAN | | Bait Gene Name | IKZF1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 34-38 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20283 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10766745 | | Comments | CtBP interacts with human DNA-binding protein Ikaros through a PEDLS motif present at the N terminus of Ikaros |
Record No : 26 |
| Instance ID | 10284 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PLDLS | | Bait Uniprot Accession | P03254 | | Bait Uniprot Identifier | E1A_ADE02 | | Bait Gene Name | Not Available | | Bait Organism | Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2) | | Sequence Position | 279-283 | | Critical Residues | P1; P2; P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Pull down; Co-IP; Mutation analysis | | Interaction ID | 20284 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 7479821 | | Comments | C-terminal binding protein (CtBP) interacts with a conserved C-terminal motif of adenovirus E1A (exon 2), which may play a critical role in adenovirus replication and oncogenic transformation |
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