Query 'EF hand' matched 37 Records
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Record No : 1 |
| Instance ID | 10474 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | EVSAIVIQRAYRRYLLKQKV | | Bait Uniprot Accession | P04775 | | Bait Uniprot Identifier | SCN2A_RAT | | Bait Gene Name | Scn2a | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1906-1925 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Fluorescence polarization spectroscopy; NMR | | Interaction ID | 20474 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 21439835 | | Comments | The Calmodulin binding IQ motif of the rat Na(V)1.2 voltage-dependent sodium channel (Scn2a) that binds to the apo C-domain of Paramecium Calmodulin (CaM) |
Record No : 2 |
| Instance ID | 10475 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | VRVVLFLQKVWRGTLARMR | | Bait Uniprot Accession | Q63357 | | Bait Uniprot Identifier | MYO1D_RAT | | Bait Gene Name | Myo1d | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 699-717 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Co-IP; Overlay assay | | Interaction ID | 20475 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8034741 | | Comments | The Calmodulin binding IQ motif of the rat Unconventional Myosin heavy chain myr 4 (Myo1d) that binds to the apo C-domain of rat Calmodulin (CaM) |
Record No : 3 |
| Instance ID | 10476 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | FYATFLIQEYFRKFKKRKEQ | | Bait Uniprot Accession | P15381 | | Bait Uniprot Identifier | CAC1C_RABIT | | Bait Gene Name | CACNA1C | | Bait Organism | Oryctolagus cuniculus (Rabbit) | | Sequence Position | 1648-1667 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Fluorescence polarization spectroscopy; NMR | | Interaction ID | 20476 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 21757287 | | Comments | The Calmodulin binding IQ motif of the rabbit Voltage-gated calcium channel subunit alpha Cav1.2 (CACNA1C) that binds to the apo C-domain of rat Calmodulin (CaM) |
Record No : 4 |
| Instance ID | 10477 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | FYATFLIQEYFRKFKKRKEQ | | Bait Uniprot Accession | Q13936 | | Bait Uniprot Identifier | CAC1C_HUMAN | | Bait Gene Name | CACNA1C | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1666-1685 | | Critical Residues | P7; P8 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Alanine scanning; X-ray crystallography | | Interaction ID | 20477 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16338416 | | Comments | Human Ca2+-calmodulin binds to the hydrophobic IQ motif of the human cardiac Ca(v)1.2 calcium channel that is required for its Ca2+-dependent inactivation (CDI) and facilitation (CDF) |
Record No : 5 |
| Instance ID | 10478 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | KDEVVKIQSLARMHQARKRY | | Bait Uniprot Accession | P46940 | | Bait Uniprot Identifier | IQGA1_HUMAN | | Bait Gene Name | IQGAP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 806-825 | | Critical Residues | P7; P8; P12; P17 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20478 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12446675 | | Comments | Interaction of Calmodulin (CALM1) with the IQ motif (806-825) of human Ras GTPase-activating-like protein IQGAP1 |
Record No : 6 |
| Instance ID | 10479 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | INDIIKIQAFIRANKARDD | | Bait Uniprot Accession | P46940 | | Bait Uniprot Identifier | IQGA1_HUMAN | | Bait Gene Name | IQGAP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 836-854 | | Critical Residues | P7; P8; P12; P17 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20479 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12446675 | | Comments | Interaction of Calmodulin (CALM1) with the IQ motif (836-854) of human Ras GTPase-activating-like protein IQGAP1 |
Record No : 7 |
| Instance ID | 10480 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | IRAAIFIQKWYRRHQARREM | | Bait Uniprot Accession | P40421 | | Bait Uniprot Identifier | RDGC_DROME | | Bait Gene Name | rdgC | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 6-25 | | Critical Residues | P7 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Western blot; Mutation analysis; Far Western blotting | | Interaction ID | 20480 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11754840 | | Comments | Retinal degeneration C protein or rhodopsin phosphatase encoded by the rdgC locus of Drosophila binds to Calmodulin (CaM) via its IQ motif |
Record No : 8 |
| Instance ID | 10481 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | NAAAAKIQASFRGHMARKKI | | Bait Uniprot Accession | P35722 | | Bait Uniprot Identifier | NEUG_BOVIN | | Bait Gene Name | NRGN | | Bait Organism | Bos taurus (Bovine) | | Sequence Position | 27-46 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | NMR | | Interaction ID | 20481 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12689827 | | Comments | Interaction between calcium-free calmodulin and IQ motif of bovine Neurogranin |
Record No : 9 |
| Instance ID | 10482 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | TLAAIKIQRTYRGWLLVREC | | Bait Uniprot Accession | P22467 | | Bait Uniprot Identifier | MYOA_DICDI | | Bait Gene Name | myoA | | Bait Organism | Dictyostelium discoideum (Slime mold) | | Sequence Position | 746-765 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | ITC; Cosedimentation; Mutation analysis; Western blot | | Interaction ID | 20482 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 21671662 | | Comments | Interaction of Dictyostelium discoideum Calmodulin (CaM) with the IQ motif of Myosin IA heavy chain |
Record No : 10 |
| Instance ID | 10483 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | PRIVTLIQKTWRGYRARSK | | Bait Uniprot Accession | Q03479 | | Bait Uniprot Identifier | MYOE_DICDI | | Bait Gene Name | myoE | | Bait Organism | Dictyostelium discoideum (Slime mold) | | Sequence Position | 697-715 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | ITC; Cosedimentation; Mutation analysis; Western blot | | Interaction ID | 20483 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 21671662 | | Comments | Interaction of Dictyostelium discoideum Calmodulin (CaM) with the IQ motif (697-715) of Myosin IE heavy chain |
Record No : 11 |
| Instance ID | 10484 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | RKAAIKIQLFYRSYRYKKWF | | Bait Uniprot Accession | Q03479 | | Bait Uniprot Identifier | MYOE_DICDI | | Bait Gene Name | myoE | | Bait Organism | Dictyostelium discoideum (Slime mold) | | Sequence Position | 719-738 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | ITC; Cosedimentation; Mutation analysis; Western blot | | Interaction ID | 20484 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 21671662 | | Comments | Interaction of Dictyostelium discoideum Calmodulin (CaM) with the IQ motif (719-738) of Myosin IE heavy chain |
Record No : 12 |
| Instance ID | 10485 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | LYCVVIIQKNYRAFLLRRRF | | Bait Uniprot Accession | Q9HD67 | | Bait Uniprot Identifier | MYO10_HUMAN | | Bait Gene Name | MYO10 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 766-785 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Comigration in gel electrophoresis; Competition binding | | Interaction ID | 20485 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20731332 | | Comments | Interaction of Calmodulin (CALM1) with the IQ motif (766-785) of human Unconventional myosin-10 |
Record No : 13 |
| Instance ID | 10486 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | KKAAIVFQKQLRGQIARRVY | | Bait Uniprot Accession | Q9HD67 | | Bait Uniprot Identifier | MYO10_HUMAN | | Bait Gene Name | MYO10 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 789-808 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Comigration in gel electrophoresis; Competition binding | | Interaction ID | 20486 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20731332 | | Comments | Interaction of Calmodulin (CALM1) with the IQ motif (789-808) of human Unconventional myosin-10 |
Record No : 14 |
| Instance ID | 10487 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | SQAIKYLQNNIKGFIIRQRV | | Bait Uniprot Accession | P19524 | | Bait Uniprot Identifier | MYO2_YEAST | | Bait Gene Name | MYO2 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 808-827 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | FRET; X-ray crystallography | | Interaction ID | 20487 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16120677 | | Comments | Calmodulin-like myosin light chain MLC1 binds to the IQ motif (808-827) of Myosin-2, a myosin V from Saccharomyces cerevisiae |
Record No : 15 |
| Instance ID | 10488 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | VNCATLLQAAYRGHSIRAN | | Bait Uniprot Accession | P19524 | | Bait Uniprot Identifier | MYO2_YEAST | | Bait Gene Name | MYO2 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 833-851 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | FRET; X-ray crystallography | | Interaction ID | 20488 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16120677 | | Comments | Calmodulin-like myosin light chain MLC1 binds to the IQ motif (833-851) of Myosin-2, a myosin V from Saccharomyces cerevisiae |
Record No : 16 |
| Instance ID | 10489 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | ERAAVAIQSQFRKFQKKKAG | | Bait Uniprot Accession | P48539 | | Bait Uniprot Identifier | PCP4_HUMAN | | Bait Gene Name | PCP4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 40-59 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | FRET; NMR | | Interaction ID | 20489 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17991744 | | Comments | The IQ motif of human Brain-specific polypeptide PEP-19 that binds preferentially to the C-domain of Calmodulin (CaM) |
Record No : 17 |
| Instance ID | 10490 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | AVVLGLVQSLNRQRQKQLL | | Bait Uniprot Accession | P40146 | | Bait Uniprot Identifier | ADCY8_RAT | | Bait Gene Name | Adcy8 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1191-1209 | | Critical Residues | P7; P8; P12; P14 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation analysis; Pull down(GST tag) | | Interaction ID | 20490 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 19305019 | | Comments | The Calmodulin binding IQ motif of the rat Ca(2+)/calmodulin-activated Adenylate cyclase type 8 (Adcy8) that binds to the apo C-domain of rat Calmodulin (CaM) |
Record No : 18 |
| Instance ID | 10491 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | ISAATRIQASFRMHKNRMA | | Bait Uniprot Accession | P05548 | | Bait Uniprot Identifier | CAVPT_BRALA | | Bait Gene Name | Not Available | | Bait Organism | Branchiostoma lanceolatum (Common lancelet) (Amphioxus lanceolatum) | | Sequence Position | 34-52 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | EMSA | | Interaction ID | 20491 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8900139 | | Comments | Calcium vector protein target (CaVPT) from Amphioxus binds to bovine brain Calmodulin (CaM) through the IQ motif |
Record No : 19 |
| Instance ID | 10492 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | IKKIKKVQSFMRGWLCRRKW | | Bait Uniprot Accession | P70392 | | Bait Uniprot Identifier | RGRF2_MOUSE | | Bait Gene Name | Rasgrf2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 206-225 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation analysis; Co-IP | | Interaction ID | 20492 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9032266 | | Comments | The Calmodulin binding IQ motif of mouse Ras guanine nucleotide exchange factor 2 (Ras-GRF2) that is required for its apparent constitutive association with calmodulin in epithelial cells ectopically expressing Ras-GRF2 |
Record No : 20 |
| Instance ID | 10493 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | KRSAICIQSWWRGTLGRRKA | | Bait Uniprot Accession | Q9WTI7 | | Bait Uniprot Identifier | MYO1C_MOUSE | | Bait Gene Name | Myo1c | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 758-777 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | FRET; Fluorescence polarization spectroscopy; Sedimentation Assay | | Interaction ID | 20493 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17910470 | | Comments | The Calmodulin binding IQ motif (758-777) of mouse Unconventional myosin-Ic that binds to chicken Calmodulin (CaM) |
Record No : 21 |
| Instance ID | 10494 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | EVSAVVLQRAYRGHLARRGF | | Bait Uniprot Accession | Q9WTU3 | | Bait Uniprot Identifier | SCN8A_MOUSE | | Bait Gene Name | Scn8a | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 1894-1913 | | Critical Residues | P7; P8 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation analysis; Pull down(GST tag) | | Interaction ID | 20494 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12967988 | | Comments | Bovine Calmodulin binds to the C terminus of mouse Voltage-gated sodium channel subunit alpha Nav1.6 |
Record No : 22 |
| Instance ID | 10495 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | EVCAIKIQRAYRRHLLQRSV | | Bait Uniprot Accession | P15390 | | Bait Uniprot Identifier | SCN4A_RAT | | Bait Gene Name | Scn4a | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1721-1740 | | Critical Residues | P7; P8 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation analysis; Co-IP; Pull down(GST tag) | | Interaction ID | 20495 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12967988 | | Comments | Bovine Calmodulin binds to the C terminus of rat Voltage-gated sodium channel subunit alpha Nav1.4 |
Record No : 23 |
| Instance ID | 10496 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | EVSAMVIQRAFRRHLLQRSL | | Bait Uniprot Accession | Q14524 | | Bait Uniprot Identifier | SCN5A_HUMAN | | Bait Gene Name | SCN5A | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1902-1921 | | Critical Residues | P7; P8; P9; P11; P12 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Fluorescence technology; Co-IP; Mutation analysis; NMR; Alanine scanning | | Interaction ID | 20496 | | Interacting Domain | EF hand | | Disease Association(s) | Brugada syndrome; Long QT syndrome | | Inhibitor(s) | Unknown | | Reference(s) | 16505387, 21167176 | | Comments | The ubiquitous calcium sensor protein calmodulin (CaM) binds to the human voltage-gated sodium channel NaV1.5 IQ motif |
Record No : 24 |
| Instance ID | 10497 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | QSLATKIQAAWRGFHWRQKF | | Bait Uniprot Accession | Q9WTI7 | | Bait Uniprot Identifier | MYO1C_MOUSE | | Bait Gene Name | Myo1c | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 735-754 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | FRET; Fluorescence polarization spectroscopy | | Interaction ID | 20497 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17910470 | | Comments | The Calmodulin binding IQ motif (735-754) of mouse Unconventional myosin-Ic that binds to chicken Calmodulin (CaM) |
Record No : 25 |
| Instance ID | 10498 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | QCTLNSLQAMKRRLGSKTT | | Bait Uniprot Accession | Q39575 | | Bait Uniprot Identifier | DYHG_CHLRE | | Bait Gene Name | ODA2 | | Bait Organism | Chlamydomonas reinhardtii (Chlamydomonas smithii) | | Sequence Position | 869-887 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Co-IP; In-vitro binding assay | | Interaction ID | 20498 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17634291 | | Comments | Ca2+-dependent Interaction of the first EF hand of Chlamydomonas Flagellar outer dynein arm 18 kDa light chain LC4 with the IQ Motif region (869-887) of Dynein gamma chain |
Record No : 26 |
| Instance ID | 10499 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | DIAAFKIQAVYKGYKVRKAF | | Bait Uniprot Accession | O89019 | | Bait Uniprot Identifier | INVS_MOUSE | | Bait Gene Name | Invs | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 556-575 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Far Western blotting | | Interaction ID | 20499 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11737147 | | Comments | The Calmodulin binding IQ motif (IQ1:556-575) of the mouse Inversin that binds to the apo C-domain of mouse Calmodulin (CaM) |
Record No : 27 |
| Instance ID | 10500 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | NKAAAVIQRAWRSYQLRKHL | | Bait Uniprot Accession | O89019 | | Bait Uniprot Identifier | INVS_MOUSE | | Bait Gene Name | Invs | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 915-934 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation analysis; Y2H; Far Western blotting | | Interaction ID | 20500 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11737147 | | Comments | The Calmodulin binding IQ motif (IQ2:915-934) of the mouse Inversin that binds to the apo C-domain of mouse Calmodulin (CaM) |
Record No : 28 |
| Instance ID | 10501 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | VKKVIKVQSMMRALLARKRV | | Bait Uniprot Accession | P10676 | | Bait Uniprot Identifier | NINAC_DROME | | Bait Gene Name | ninaC | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 1037-1057 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Co-IP; Classical fluorescence spectroscopy; Mutation analysis | | Interaction ID | 20501 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 7556088 | | Comments | The Calmodulin binding IQ motif (1037-1057) of Drosophila NinaC that binds to Drosophila Calmodulin (CaM) |
Record No : 29 |
| Instance ID | 10502 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | DVAASKIQKAFRGFRDRVR | | Bait Uniprot Accession | P10676 | | Bait Uniprot Identifier | NINAC_DROME | | Bait Gene Name | ninaC | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 1073-1091 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Classical fluorescence spectroscopy; Co-IP; Far Western blotting; Mutation analysis | | Interaction ID | 20502 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 7556088 | | Comments | The Calmodulin binding IQ motif (1073-1091) of Drosophila NinaC that binds to Drosophila Calmodulin (CaM) |
Record No : 30 |
| Instance ID | 10503 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | HKAATKIQASFRGHITRKKL | | Bait Uniprot Accession | P06836 | | Bait Uniprot Identifier | NEUM_BOVIN | | Bait Gene Name | GAP43 | | Bait Organism | Bos taurus (Bovine) | | Sequence Position | 32-51 | | Critical Residues | Unknown | | Motif PTM(s) | Phosphorylation at Ser-P10 | | Secondary Structure | Alpha helix | | Experimental Method(s) | Affinity chromatography technology; Mutation analysis; Fluorescence polarization spectroscopy | | Interaction ID | 20503 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 1824693 | | Comments | Interaction between bovine Neuromodulin (Growth-associated protein 43 or GAP43) and Calmodulin (CaM) via the IQ motif of GAP43 that is disrupted by protein kinase C phosphorylation of neuromodulin at serine 41 |
Record No : 31 |
| Instance ID | 10504 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | IVAALKIQHAFRNYNRKKAM | | Bait Uniprot Accession | Q2WEL1 | | Bait Uniprot Identifier | Q2WEL1_ORYSA | | Bait Gene Name | CBT | | Bait Organism | Oryza sativa (Rice) | | Sequence Position | 758-777 | | Critical Residues | P7 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Far Western blotting; Mutation analysis; EMSA | | Interaction ID | 20504 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16192280 | | Comments | Calmodulin (CaM) binds to the IQ motif of a calmodulin-binding transcription factor from rice, OsCBT (Oryza sativa CaM-binding transcription factor) |
Record No : 32 |
| Instance ID | 10505 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | EEAAVIIQRTFRNHKKQSY | | Bait Uniprot Accession | Q54T86 | | Bait Uniprot Identifier | DWWA_DICDI | | Bait Gene Name | dwwA | | Bait Organism | Dictyostelium discoideum (Slime mold) | | Sequence Position | 462-480 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Pull down | | Interaction ID | 20505 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14595117 | | Comments | Interaction of Dictyostelium discoideum Calmodulin (CaM) with the IQ motif of Dd WW domain containing protein A (DWWA), which is required for cytokinesis of Dictyostelium cells on solid surfaces |
Record No : 33 |
| Instance ID | 10506 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | FYATFLIQEHFRKFMKRQEE | | Bait Uniprot Accession | Q13698 | | Bait Uniprot Identifier | CAC1S_HUMAN | | Bait Gene Name | CACNA1S | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1523-1542 | | Critical Residues | P10; P15; P18 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation analysis; SPR; X-ray crystallography | | Interaction ID | 20506 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 19473981 | | Comments | Human Calmodulin (CALM1) binds to the IQ motif in the alpha(1) subunit of human Voltage-gated calcium channel subunit alpha Ca(V)1.1 |
Record No : 34 |
| Instance ID | 10507 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | SDNLTRLQVGFKRELIKEV | | Bait Uniprot Accession | Q39575 | | Bait Uniprot Identifier | DYHG_CHLRE | | Bait Gene Name | ODA2 | | Bait Organism | Chlamydomonas reinhardtii (Chlamydomonas smithii) | | Sequence Position | 1157-1175 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Co-IP; In-vitro binding assay | | Interaction ID | 20507 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17634291 | | Comments | Ca2+-dependent Interaction of the first EF hand of Chlamydomonas Flagellar outer dynein arm 18 kDa light chain LC4 with the IQ Motif region (1157-1175) of Dynein gamma chain |
Record No : 35 |
| Instance ID | 10508 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | CVILPEIQKPERKIQFKEK | | Bait Uniprot Accession | P38377 | | Bait Uniprot Identifier | S61A1_CANFA | | Bait Gene Name | SEC61A1 | | Bait Organism | Canis familiaris (Dog) (Canis lupus familiaris) | | Sequence Position | 13-31 | | Critical Residues | P12 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Fluorescence correlation spectroscopy; Peptide‐spot binding assay; Alanine scanning | | Interaction ID | 20508 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 21102557 | | Comments | The Calmodulin binding IQ motif in the cytosolic N-terminus of Protein transport protein Sec61 alpha-1 of Canis lupus familiaris that bound CaM but not Ca2+-free apocalmodulin with nanomolar affinity and sequence specificity |
Record No : 36 |
| Instance ID | 10509 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | EVSAVIIQRAYRRHLLKRTV | | Bait Uniprot Accession | P04774 | | Bait Uniprot Identifier | SCN1A_RAT | | Bait Gene Name | Scn1a | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1916-1935 | | Critical Residues | P7; P8 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Pull down; Co-IP; Mutation analysis | | Interaction ID | 20509 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 21726526 | | Comments | The ubiquitous calcium sensor calmodulin (CaM) binds to the IQ Motif of rat brain Voltage-gated sodium channel subunit alpha Nav1.1 |
Record No : 37 |
| Instance ID | 10510 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | FKAAALIQRWYRRYVARLE | | Bait Uniprot Accession | O14830 | | Bait Uniprot Identifier | PPE2_HUMAN | | Bait Gene Name | PPEF2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 20-38 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Competition binding; SPR; Y2H; Western blot | | Interaction ID | 20510 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12051765, 11754840 | | Comments | The Calmodulin binding IQ motif in the N-terminal domain of human Protein Ser/Thr phosphatase PPEF2 interacts with murine Calmodulin (CaM) |
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