Query 'EH domain' matched 84 Records
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Record No : 1 |
| Instance ID | 10317 | | Regular Expression | xNPFx | | Motif Instance | TNPFQ | | Bait Uniprot Accession | P52594 | | Bait Uniprot Identifier | AGFG1_HUMAN | | Bait Gene Name | AGFG1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 448-452 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 20317 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9446614 | | Comments | Asn-Pro-Phe motif in human Arf-GAP domain and FG repeat-containing protein 1 that is responsible for the interaction with Eps15 homology (EH) domain of Eps15-related protein (Eps15R or EPS15L1) |
Record No : 2 |
| Instance ID | 10318 | | Regular Expression | xNPFx | | Motif Instance | TNPFL | | Bait Uniprot Accession | P52594 | | Bait Uniprot Identifier | AGFG1_HUMAN | | Bait Gene Name | AGFG1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 558-562 | | Critical Residues | P2; P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Classical fluorescence spectroscopy; Display technology; Pull down; SPR; NMR | | Interaction ID | 20318 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9303539, 9446614, 9721102, 11062555 | | Comments | Asn-Pro-Phe motif (558-562) in human Arf-GAP domain and FG repeat-containing protein 1 that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15) |
Record No : 3 |
| Instance ID | 10319 | | Regular Expression | xNPFx | | Motif Instance | TNPFQ | | Bait Uniprot Accession | O95081 | | Bait Uniprot Identifier | AGFG2_HUMAN | | Bait Gene Name | AGFG2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 380-384 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20319 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9303539 | | Comments | Asn-Pro-Phe motif (380-384) in human Arf-GAP domain and FG repeat-containing protein 2 that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15) |
Record No : 4 |
| Instance ID | 10320 | | Regular Expression | xNPFx | | Motif Instance | ANPFP | | Bait Uniprot Accession | Q62910 | | Bait Uniprot Identifier | SYNJ1_RAT | | Bait Gene Name | Synj1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1400-1404 | | Critical Residues | P2; P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Competition binding; Pull down; Far Western blotting | | Interaction ID | 20320 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9535728, 9428629 | | Comments | EH domain-dependent interaction between rat Eps15 and the 170 kDa isoform of endocytic protein Synaptojanin 1 mediated by the NPF motif (1400-1404) in the COOH-terminal region of Synaptojanin 1 |
Record No : 5 |
| Instance ID | 10321 | | Regular Expression | xNPFx | | Motif Instance | SNPFL | | Bait Uniprot Accession | O88339 | | Bait Uniprot Identifier | EPN1_RAT | | Bait Gene Name | Epn1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 500-504 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Far Western blotting; Co-IP; Pull down; Classical fluorescence spectroscopy | | Interaction ID | 20321 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9723620 | | Comments | EH domain-dependent interaction between rat Eps15 and Epsin-1 mediated by the NPF motif (500-504) in Epsin-1 |
Record No : 6 |
| Instance ID | 10322 | | Regular Expression | xNPFx | | Motif Instance | GNPFR | | Bait Uniprot Accession | Q62910 | | Bait Uniprot Identifier | SYNJ1_RAT | | Bait Gene Name | Synj1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1420-1424 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Far Western blotting; Competition binding; NMR; Pull down | | Interaction ID | 20322 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9535728, 9428629, 10757979 | | Comments | EH domain-dependent interaction between rat Eps15 and the 170 kDa isoform of endocytic protein Synaptojanin 1 mediated by the NPF motif (1420-1424) in the COOH-terminal region of Synaptojanin 1 |
Record No : 7 |
| Instance ID | 10323 | | Regular Expression | xNPFx | | Motif Instance | SNPFM | | Bait Uniprot Accession | P52594 | | Bait Uniprot Identifier | AGFG1_HUMAN | | Bait Gene Name | AGFG1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 539-543 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Pull down | | Interaction ID | 20323 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9303539, 9446614 | | Comments | Asn-Pro-Phe motif (557-561) in human Arf-GAP domain and FG repeat-containing protein 1 that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15) |
Record No : 8 |
| Instance ID | 10324 | | Regular Expression | xNPFx | | Motif Instance | TNPFL | | Bait Uniprot Accession | Q8K2K6 | | Bait Uniprot Identifier | AGFG1_MOUSE | | Bait Gene Name | Agfg1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 557-561 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | NMR | | Interaction ID | 20324 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10471276 | | Comments | EH domain-dependent interaction between mouse Eps15 and NPF-containing peptide derived from RAB, the cellular cofactor of the HIV Rev protein (Agfg1) |
Record No : 9 |
| Instance ID | 10325 | | Regular Expression | xNPFx | | Motif Instance | TNPFI | | Bait Uniprot Accession | P16554 | | Bait Uniprot Identifier | NUMB_DROME | | Bait Gene Name | numb | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 538-542 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20325 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15155807 | | Comments | NPF motif in the carboxy-terminal sequence of Numb from Drosophila that associate with Drosophila EHD or Past1 |
Record No : 10 |
| Instance ID | 10326 | | Regular Expression | xNPFx | | Motif Instance | TNPFM | | Bait Uniprot Accession | O95081 | | Bait Uniprot Identifier | AGFG2_HUMAN | | Bait Gene Name | AGFG2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 458-462 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20326 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9303539 | | Comments | Asn-Pro-Phe motif (458-462) in human Arf-GAP domain and FG repeat-containing protein 2 that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15) |
Record No : 11 |
| Instance ID | 10327 | | Regular Expression | xNPFx | | Motif Instance | TNPFV | | Bait Uniprot Accession | P52594 | | Bait Uniprot Identifier | AGFG1_HUMAN | | Bait Gene Name | AGFG1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 433-437 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Co-IP | | Interaction ID | 20327 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9303539, 9446614 | | Comments | Asn-Pro-Phe motif (433-437) in human Arf-GAP domain and FG repeat-containing protein 1 that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15) |
Record No : 12 |
| Instance ID | 10328 | | Regular Expression | xNPFx | | Motif Instance | TNPFT | | Bait Uniprot Accession | O95081 | | Bait Uniprot Identifier | AGFG2_HUMAN | | Bait Gene Name | AGFG2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 365-369 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20328 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9303539 | | Comments | Asn-Pro-Phe motif (365-369) in human Arf-GAP domain and FG repeat-containing protein 2 that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15) |
Record No : 13 |
| Instance ID | 10329 | | Regular Expression | xNPFx | | Motif Instance | SNPFS | | Bait Uniprot Accession | Q9Y6R0 | | Bait Uniprot Identifier | NUMBL_HUMAN | | Bait Gene Name | NUMBL | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 594-598 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20329 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9303539 | | Comments | Asn-Pro-Phe motif in human Numb-like protein that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15) |
Record No : 14 |
| Instance ID | 10330 | | Regular Expression | xNPFx | | Motif Instance | TNPFL | | Bait Uniprot Accession | O95081 | | Bait Uniprot Identifier | AGFG2_HUMAN | | Bait Gene Name | AGFG2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 477-481 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20330 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9303539 | | Comments | Asn-Pro-Phe motif (477-481) in human Arf-GAP domain and FG repeat-containing protein 2 that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15) |
Record No : 15 |
| Instance ID | 10331 | | Regular Expression | xNPFx | | Motif Instance | RNPFT | | Bait Uniprot Accession | Q62910 | | Bait Uniprot Identifier | SYNJ1_RAT | | Bait Gene Name | Synj1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1409-1413 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Competition binding; Pull down; Far Western blotting | | Interaction ID | 20331 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9535728, 9428629 | | Comments | EH domain-dependent interaction between rat Eps15 and the 170 kDa isoform of endocytic protein Synaptojanin 1 mediated by the NPF motif (1409-1413) in the COOH-terminal region of Synaptojanin 1 |
Record No : 16 |
| Instance ID | 10332 | | Regular Expression | xNPFx | | Motif Instance | TNPFQ | | Bait Uniprot Accession | O88339 | | Bait Uniprot Identifier | EPN1_RAT | | Bait Gene Name | Epn1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 516-520 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Far Western blotting; Pull down; Co-IP | | Interaction ID | 20332 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9723620 | | Comments | EH domain-dependent interaction between rat Eps15 and Epsin-1 mediated by the NPF motif (516-520) in Epsin-1 |
Record No : 17 |
| Instance ID | 10333 | | Regular Expression | xNPFx | | Motif Instance | TNPFS | | Bait Uniprot Accession | P49757 | | Bait Uniprot Identifier | NUMB_HUMAN | | Bait Gene Name | NUMB | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 636-640 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Pull down; Display technology; Mutation analysis | | Interaction ID | 20333 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9303539 | | Comments | Asn-Pro-Phe motif in human homolog of NUMB that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15) |
Record No : 18 |
| Instance ID | 10334 | | Regular Expression | xNPFx | | Motif Instance | TNPFL | | Bait Uniprot Accession | O88339 | | Bait Uniprot Identifier | EPN1_RAT | | Bait Gene Name | Epn1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 570-574 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Far Western blotting; Pull down; Co-IP | | Interaction ID | 20334 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9723620 | | Comments | EH domain-dependent interaction between rat Eps15 and Epsin-1 mediated by the NPF motif (570-574) in Epsin-1 |
Record No : 19 |
| Instance ID | 10335 | | Regular Expression | xNPFx | | Motif Instance | LNPFD | | Bait Uniprot Accession | Q9H1K0 | | Bait Uniprot Identifier | RBNS5_HUMAN | | Bait Gene Name | ZFYVE20 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 625-629 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Classical fluorescence spectroscopy; Y2H | | Interaction ID | 20335 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15020713 | | Comments | Rabenosyn-5 and EHD1 interact and sequentially regulate protein recycling to the plasma membrane through the NPF motif (625-629) of Rabenosyn-5 |
Record No : 20 |
| Instance ID | 10336 | | Regular Expression | xNPFx | | Motif Instance | SNPFL | | Bait Uniprot Accession | Q80VP1 | | Bait Uniprot Identifier | EPN1_MOUSE | | Bait Gene Name | Epn1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 500-504 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 20336 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10064583 | | Comments | EH domain-dependent interaction between mouse Eps15 and Epsin-1 mediated by the NPF motif (500-504) in Epsin-1 |
Record No : 21 |
| Instance ID | 10337 | | Regular Expression | xNPFx | | Motif Instance | TNPFQ | | Bait Uniprot Accession | Q80VP1 | | Bait Uniprot Identifier | EPN1_MOUSE | | Bait Gene Name | Epn1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 516-520 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 20337 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10064583 | | Comments | EH domain-dependent interaction between mouse Eps15 and Epsin-1 mediated by the NPF motif (516-520) in Epsin-1 |
Record No : 22 |
| Instance ID | 10338 | | Regular Expression | xNPFx | | Motif Instance | TNPFL | | Bait Uniprot Accession | Q80VP1 | | Bait Uniprot Identifier | EPN1_MOUSE | | Bait Gene Name | Epn1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 570-574 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 20338 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10064583 | | Comments | EH domain-dependent interaction between mouse Eps15 and Epsin-1 mediated by the NPF motif (570-574) in Epsin-1 |
Record No : 23 |
| Instance ID | 10339 | | Regular Expression | xNPFx | | Motif Instance | NNPFV | | Bait Uniprot Accession | P38856 | | Bait Uniprot Identifier | AP18A_YEAST | | Bait Gene Name | YAP1801 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 362-366 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Co-IP | | Interaction ID | 20339 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1801, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (362-366) of YAP1801 |
Record No : 24 |
| Instance ID | 10340 | | Regular Expression | xNPFx | | Motif Instance | YNPFE | | Bait Uniprot Accession | Q9H1K0 | | Bait Uniprot Identifier | RBNS5_HUMAN | | Bait Gene Name | ZFYVE20 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 661-665 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Classical fluorescence spectroscopy; Y2H | | Interaction ID | 20340 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15020713 | | Comments | Rabenosyn-5 and EHD1 interact and sequentially regulate protein recycling to the plasma membrane through the NPF motif (661-665) of Rabenosyn-5 |
Record No : 25 |
| Instance ID | 10341 | | Regular Expression | xNPFx | | Motif Instance | LNPFL | | Bait Uniprot Accession | Q8CHU3 | | Bait Uniprot Identifier | EPN2_MOUSE | | Bait Gene Name | Epn2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 493-497 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Y2H | | Interaction ID | 20341 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10336464, 10064583 | | Comments | Intersectin-1 interacts with mouse Ibp2 through its EH domain that binds the NPF motif (493-497) of Ibp2 |
Record No : 26 |
| Instance ID | 10342 | | Regular Expression | xNPFx | | Motif Instance | SNPFA | | Bait Uniprot Accession | P56603 | | Bait Uniprot Identifier | SCAM1_RAT | | Bait Gene Name | Scamp1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 6-10 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Y2H | | Interaction ID | 20342 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10777571 | | Comments | N-terminal NPF motif (6-10) of rat Secretory carrier membrane protein 1 (Scamp1) that interact with EH domain of Intersectin-1 |
Record No : 27 |
| Instance ID | 10343 | | Regular Expression | xNPFx | | Motif Instance | VNPFQ | | Bait Uniprot Accession | Q8CHU3 | | Bait Uniprot Identifier | EPN2_MOUSE | | Bait Gene Name | Epn2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 507-511 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Y2H | | Interaction ID | 20343 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10336464, 10064583 | | Comments | Intersectin-1 interacts with mouse Ibp2 through its EH domain that binds the NPF motif (507-511) of Ibp2 |
Record No : 28 |
| Instance ID | 10344 | | Regular Expression | xNPFx | | Motif Instance | VNPFQ | | Bait Uniprot Accession | O95208 | | Bait Uniprot Identifier | EPN2_HUMAN | | Bait Gene Name | EPN2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 551-555 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20344 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10567358 | | Comments | Asn-Pro-Phe motif (551-555) in human Epsin-2 that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15) |
Record No : 29 |
| Instance ID | 10345 | | Regular Expression | xNPFx | | Motif Instance | TNPFL | | Bait Uniprot Accession | Q8CHU3 | | Bait Uniprot Identifier | EPN2_MOUSE | | Bait Gene Name | Epn2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 590-594 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Pull down | | Interaction ID | 20345 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10064583, 10336464 | | Comments | Intersectin-1 interacts with mouse Ibp2 through its EH domain that binds the NPF motif (590-594) of Ibp2 |
Record No : 30 |
| Instance ID | 10346 | | Regular Expression | xNPFx | | Motif Instance | NNPFK | | Bait Uniprot Accession | P56603 | | Bait Uniprot Identifier | SCAM1_RAT | | Bait Gene Name | Scamp1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 15-19 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Y2H | | Interaction ID | 20346 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10777571 | | Comments | N-terminal NPF motif (15-19) of rat Secretory carrier membrane protein 1 (Scamp1) that interact with EH domain of Intersectin-1 |
Record No : 31 |
| Instance ID | 10347 | | Regular Expression | xNPFx | | Motif Instance | GNPFI | | Bait Uniprot Accession | Q9H1K0 | | Bait Uniprot Identifier | RBNS5_HUMAN | | Bait Gene Name | ZFYVE20 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 676-680 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20347 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15020713 | | Comments | Rabenosyn-5 and EHD1 interact and sequentially regulate protein recycling to the plasma membrane through the NPF motif (676-680) of Rabenosyn-5 |
Record No : 32 |
| Instance ID | 10348 | | Regular Expression | xNPFx | | Motif Instance | YNPFS | | Bait Uniprot Accession | P56603 | | Bait Uniprot Identifier | SCAM1_RAT | | Bait Gene Name | Scamp1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 37-41 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Y2H | | Interaction ID | 20348 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10777571 | | Comments | N-terminal NPF motif (37-41) of rat Secretory carrier membrane protein 1 (Scamp1) that interact with EH domain of Intersectin-1 |
Record No : 33 |
| Instance ID | 10349 | | Regular Expression | xNPFx | | Motif Instance | NNPFS | | Bait Uniprot Accession | P38856 | | Bait Uniprot Identifier | AP18A_YEAST | | Bait Gene Name | YAP1801 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 479-483 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Pull down; Co-IP | | Interaction ID | 20349 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1801, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (479-483) of YAP1801 |
Record No : 34 |
| Instance ID | 10350 | | Regular Expression | xNPFx | | Motif Instance | PNPFS | | Bait Uniprot Accession | Q9H1K0 | | Bait Uniprot Identifier | RBNS5_HUMAN | | Bait Gene Name | ZFYVE20 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 687-691 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20350 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15020713 | | Comments | Rabenosyn-5 and EHD1 interact and sequentially regulate protein recycling to the plasma membrane through the NPF motif (687-691) of Rabenosyn-5 |
Record No : 35 |
| Instance ID | 10351 | | Regular Expression | xNPFx | | Motif Instance | TNPFL | | Bait Uniprot Accession | Q8WXE9 | | Bait Uniprot Identifier | STON2_HUMAN | | Bait Gene Name | STON2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 312-316 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; NMR; Co-IP; Pull down; ITC; Y2H | | Interaction ID | 20351 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11381094, 18200045, 14726597 | | Comments | NPF motif (312-316) of human Stonin-2 (STON2) that interacts with the endocytic machinery protein EPS15 |
Record No : 36 |
| Instance ID | 10352 | | Regular Expression | xNPFx | | Motif Instance | INPFS | | Bait Uniprot Accession | Q8WXE9 | | Bait Uniprot Identifier | STON2_HUMAN | | Bait Gene Name | STON2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 328-332 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; NMR; Co-IP; Pull down; ITC; Y2H | | Interaction ID | 20352 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14726597, 18200045, 11381094 | | Comments | NPF motif (328-332) of human Stonin-2 (STON2) that interacts with the endocytic machinery protein EPS15 |
Record No : 37 |
| Instance ID | 10353 | | Regular Expression | xNPFx | | Motif Instance | GNPFE | | Bait Uniprot Accession | Q9H1K0 | | Bait Uniprot Identifier | RBNS5_HUMAN | | Bait Gene Name | ZFYVE20 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 708-712 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20353 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15020713 | | Comments | Rabenosyn-5 and EHD1 interact and sequentially regulate protein recycling to the plasma membrane through the NPF motif (708-712) of Rabenosyn-5 |
Record No : 38 |
| Instance ID | 10354 | | Regular Expression | xNPFx | | Motif Instance | YNPFG | | Bait Uniprot Accession | P53309 | | Bait Uniprot Identifier | AP18B_YEAST | | Bait Gene Name | YAP1802 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 339-343 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20354 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549, 11940605 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1802, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (339-343) of YAP1802 |
Record No : 39 |
| Instance ID | 10355 | | Regular Expression | xNPFx | | Motif Instance | GNPFG | | Bait Uniprot Accession | Q9Z0W5 | | Bait Uniprot Identifier | PACN1_RAT | | Bait Gene Name | Pacsin1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 363-367 | | Critical Residues | P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Co-IP; Pull down; Classical fluorescence spectroscopy; Y2H | | Interaction ID | 20355 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15930129 | | Comments | EH domain-containing protein 1 associates with rat Pacsin1/Syndapin-I via EH domain/NPF interactions through the NPF motif (363-367) of syndapin I |
Record No : 40 |
| Instance ID | 10356 | | Regular Expression | xNPFx | | Motif Instance | INPFE | | Bait Uniprot Accession | Q9H1K0 | | Bait Uniprot Identifier | RBNS5_HUMAN | | Bait Gene Name | ZFYVE20 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 717-721 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20356 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15020713 | | Comments | Rabenosyn-5 and EHD1 interact and sequentially regulate protein recycling to the plasma membrane through the NPF motif (717-721) of Rabenosyn-5 |
Record No : 41 |
| Instance ID | 10357 | | Regular Expression | xNPFx | | Motif Instance | ANPFE | | Bait Uniprot Accession | Q9Z0W5 | | Bait Uniprot Identifier | PACN1_RAT | | Bait Gene Name | Pacsin1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 375-379 | | Critical Residues | P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Co-IP; Pull down; Classical fluorescence spectroscopy; Far Western blotting; Y2H | | Interaction ID | 20357 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15930129 | | Comments | EH domain-containing protein 1 associates with rat Pacsin1/Syndapin-I via EH domain/NPF interactions through the NPF motif (375-379) of syndapin I |
Record No : 42 |
| Instance ID | 10358 | | Regular Expression | xNPFx | | Motif Instance | YNPFE | | Bait Uniprot Accession | Q9QY17 | | Bait Uniprot Identifier | PACN2_RAT | | Bait Gene Name | Pacsin2 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 363-367 | | Critical Residues | P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Co-IP; Pull down; Far Western blotting | | Interaction ID | 20358 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15930129, 15371016 | | Comments | EH domain-containing protein 1 associates with rat Pacsin2/Syndapin-II via EH domain/NPF interactions through the NPF motif (363-367) of syndapin II |
Record No : 43 |
| Instance ID | 10359 | | Regular Expression | xNPFx | | Motif Instance | KNPFE | | Bait Uniprot Accession | Q3I768 | | Bait Uniprot Identifier | Q3I768_HUMAN | | Bait Gene Name | RAB11FIP2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 322-326 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | NMR; Co-IP; Classical fluorescence spectroscopy; Y2H | | Interaction ID | 20359 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12364336, 16251358 | | Comments | Interaction between EHD1 and Rab11-FIP2 through the NPF motif (322-326) of RAB11FIP2 |
Record No : 44 |
| Instance ID | 10360 | | Regular Expression | xNPFx | | Motif Instance | NNPFS | | Bait Uniprot Accession | Q9QY17 | | Bait Uniprot Identifier | PACN2_RAT | | Bait Gene Name | Pacsin2 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 406-410 | | Critical Residues | P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Co-IP; Pull down; Far Western blotting | | Interaction ID | 20360 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15930129, 15371016 | | Comments | EH domain-containing protein 1 associates with rat Pacsin2/Syndapin-II via EH domain/NPF interactions through the NPF motif (406-410) of syndapin II |
Record No : 45 |
| Instance ID | 10361 | | Regular Expression | xNPFx | | Motif Instance | SNPFD | | Bait Uniprot Accession | Q9QY17 | | Bait Uniprot Identifier | PACN2_RAT | | Bait Gene Name | Pacsin2 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 418-422 | | Critical Residues | P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Co-IP; Pull down; Far Western blotting | | Interaction ID | 20361 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15930129, 15371016 | | Comments | EH domain-containing protein 1 associates with rat Pacsin2/Syndapin-II via EH domain/NPF interactions through the NPF motif (418-422) of syndapin II |
Record No : 46 |
| Instance ID | 10362 | | Regular Expression | xNPFx | | Motif Instance | NNPFS | | Bait Uniprot Accession | P53309 | | Bait Uniprot Identifier | AP18B_YEAST | | Bait Gene Name | YAP1802 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 452-456 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20362 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549, 11940605 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1802, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (452-456) of YAP1802 |
Record No : 47 |
| Instance ID | 10363 | | Regular Expression | xNPFx | | Motif Instance | TNPFT | | Bait Uniprot Accession | Q3I768 | | Bait Uniprot Identifier | Q3I768_HUMAN | | Bait Gene Name | RAB11FIP2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 405-409 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | NMR; Co-IP; Classical fluorescence spectroscopy; Pull down; Y2H | | Interaction ID | 20363 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11389591, 16251358, 12364336 | | Comments | Interaction between EHD1 and Rab11-FIP2 through the NPF motif (405-409) of RAB11FIP2 |
Record No : 48 |
| Instance ID | 10364 | | Regular Expression | xNPFx | | Motif Instance | SNPFD | | Bait Uniprot Accession | Q3I768 | | Bait Uniprot Identifier | Q3I768_HUMAN | | Bait Gene Name | RAB11FIP2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 459-463 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | NMR | | Interaction ID | 20364 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12364336 | | Comments | Interaction between EHD1 and Rab11-FIP2 through the NPF motif (459-463) of RAB11FIP2 |
Record No : 49 |
| Instance ID | 10365 | | Regular Expression | xNPFx | | Motif Instance | GNPFQ | | Bait Uniprot Accession | P53309 | | Bait Uniprot Identifier | AP18B_YEAST | | Bait Gene Name | YAP1802 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 493-497 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20365 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549, 11940605 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1802, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (493-497) of YAP1802 |
Record No : 50 |
| Instance ID | 10366 | | Regular Expression | xNPFx | | Motif Instance | LNPFL | | Bait Uniprot Accession | O55012 | | Bait Uniprot Identifier | PICAL_RAT | | Bait Gene Name | Picalm | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 429-433 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Classical fluorescence spectroscopy | | Interaction ID | 20366 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15182197 | | Comments | EHD2 interacts with rat Clathrin assembly lymphoid myeloid leukemia protein (Calm) through the NPF motif (429-433) of rCALM |
Record No : 51 |
| Instance ID | 10367 | | Regular Expression | xNPFx | | Motif Instance | PNPFG | | Bait Uniprot Accession | O55012 | | Bait Uniprot Identifier | PICAL_RAT | | Bait Gene Name | Picalm | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 626-630 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Classical fluorescence spectroscopy | | Interaction ID | 20367 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15182197 | | Comments | EHD2 interacts with rat Clathrin assembly lymphoid myeloid leukemia protein (Calm) through the NPF motif (626-630) of rCALM |
Record No : 52 |
| Instance ID | 10368 | | Regular Expression | xNPFx | | Motif Instance | ANPFQ | | Bait Uniprot Accession | P34552 | | Bait Uniprot Identifier | ALX1_CAEEL | | Bait Gene Name | alx-1 | | Bait Organism | Caenorhabditis elegans | | Sequence Position | 878-882 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Pull down; Mutation analysis | | Interaction ID | 20368 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17997305 | | Comments | The interaction of ALX-1 with RME-1 in C. elegans, mediated by RME-1/YPSL and ALX-1/NPF motifs |
Record No : 53 |
| Instance ID | 10369 | | Regular Expression | xNPFx | | Motif Instance | NNPFQ | | Bait Uniprot Accession | Q04206 | | Bait Uniprot Identifier | TF65_HUMAN | | Bait Gene Name | RELA | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 138-142 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20369 | | Interacting Domain | EH domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 15184881 | | Comments | The NPF-motif in human Transcription factor p65 (NF-kappaB subunit p65 or RELA) that acts as binding site for the EH domain in REPS2 |
Record No : 54 |
| Instance ID | 10370 | | Regular Expression | xNPFx | | Motif Instance | YNPFG | | Bait Uniprot Accession | P38856 | | Bait Uniprot Identifier | AP18A_YEAST | | Bait Gene Name | YAP1801 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 336-340 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP | | Interaction ID | 20370 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1801, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (336-340) of YAP1801 |
Record No : 55 |
| Instance ID | 10371 | | Regular Expression | xNPFx | | Motif Instance | YNPFD | | Bait Uniprot Accession | Q9Z2P6 | | Bait Uniprot Identifier | SNP29_RAT | | Bait Gene Name | Snap29 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 8-12 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down(His tag); Pull down(GST tag); Co-IP | | Interaction ID | 20371 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15371016 | | Comments | EH domain-containing protein 1 associates with rat Synaptosomal-associated protein 29 (Snap29) via EH domain/NPF interactions through the NPF motif of Snap29 |
Record No : 56 |
| Instance ID | 10372 | | Regular Expression | xNPFx | | Motif Instance | NNPFA | | Bait Uniprot Accession | P38856 | | Bait Uniprot Identifier | AP18A_YEAST | | Bait Gene Name | YAP1801 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 456-460 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Pull down; Co-IP | | Interaction ID | 20372 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1801, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (456-460) of YAP1801 |
Record No : 57 |
| Instance ID | 10373 | | Regular Expression | xNPFx | | Motif Instance | SNPFQ | | Bait Uniprot Accession | P38856 | | Bait Uniprot Identifier | AP18A_YEAST | | Bait Gene Name | YAP1801 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 502-506 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Pull down; Co-IP | | Interaction ID | 20373 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1801, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (502-506) of YAP1801 |
Record No : 58 |
| Instance ID | 10374 | | Regular Expression | xNPFx | | Motif Instance | ANPFL | | Bait Uniprot Accession | P53309 | | Bait Uniprot Identifier | AP18B_YEAST | | Bait Gene Name | YAP1802 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 372-376 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20374 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11940605 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1802, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (372-376) of YAP1802 |
Record No : 59 |
| Instance ID | 10375 | | Regular Expression | xNPFx | | Motif Instance | PNPFT | | Bait Uniprot Accession | P53309 | | Bait Uniprot Identifier | AP18B_YEAST | | Bait Gene Name | YAP1802 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 473-477 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20375 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549, 11940605 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1802, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (473-477) of YAP1802 |
Record No : 60 |
| Instance ID | 10376 | | Regular Expression | xNPFx | | Motif Instance | NNPFA | | Bait Uniprot Accession | Q12518 | | Bait Uniprot Identifier | ENT1_YEAST | | Bait Gene Name | ENT1 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 305-309 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Pull down | | Interaction ID | 20376 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12529323, 9531549 | | Comments | The yeast Epsin Ent1 NPF motif (305-309) interact with the EH domain-containing protein Pan1 |
Record No : 61 |
| Instance ID | 10377 | | Regular Expression | xNPFx | | Motif Instance | HNPFL | | Bait Uniprot Accession | Q12518 | | Bait Uniprot Identifier | ENT1_YEAST | | Bait Gene Name | ENT1 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 406-410 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutation analysis; Pull down | | Interaction ID | 20377 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12529323, 9531549 | | Comments | The yeast Epsin Ent1 NPF motif (406-410) interact with the EH domain-containing protein Pan1 |
Record No : 62 |
| Instance ID | 10378 | | Regular Expression | xNPFx | | Motif Instance | NNPFS | | Bait Uniprot Accession | Q05785 | | Bait Uniprot Identifier | ENT2_YEAST | | Bait Gene Name | ENT2 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 346-350 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20378 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549 | | Comments | The yeast Epsin Ent1 NPF motif (346-350) interact with the EH domain-containing protein Pan1 |
Record No : 63 |
| Instance ID | 10379 | | Regular Expression | xNPFx | | Motif Instance | NNPFL | | Bait Uniprot Accession | Q05785 | | Bait Uniprot Identifier | ENT2_YEAST | | Bait Gene Name | ENT2 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 490-494 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20379 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549 | | Comments | The yeast Epsin Ent1 NPF motif (490-494) interact with the EH domain-containing protein Pan1 |
Record No : 64 |
| Instance ID | 10380 | | Regular Expression | xNPFx | | Motif Instance | PNPFV | | Bait Uniprot Accession | P40559 | | Bait Uniprot Identifier | INP51_YEAST | | Bait Gene Name | INP51 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 931-935 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP | | Interaction ID | 20380 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15265867 | | Comments | INP51 associates with the EH Domain-containing protein TAX4 via its NPF motif in Saccharomyces cerevisiae |
Record No : 65 |
| Instance ID | 10381 | | Regular Expression | xNPFx | | Motif Instance | PNPFV | | Bait Uniprot Accession | P40559 | | Bait Uniprot Identifier | INP51_YEAST | | Bait Gene Name | INP51 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 931-935 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP | | Interaction ID | 20381 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15265867 | | Comments | INP51 associates with the EH Domain-containing protein IRS4 via its NPF motif in Saccharomyces cerevisiae |
Record No : 66 |
| Instance ID | 10382 | | Regular Expression | xNPFx | | Motif Instance | LNPFL | | Bait Uniprot Accession | O95208 | | Bait Uniprot Identifier | EPN2_HUMAN | | Bait Gene Name | EPN2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 536-540 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20382 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10567358 | | Comments | Asn-Pro-Phe motif (536-540) in human Epsin-2 that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15) |
Record No : 67 |
| Instance ID | 10383 | | Regular Expression | xNPFx | | Motif Instance | TNPFL | | Bait Uniprot Accession | O95208 | | Bait Uniprot Identifier | EPN2_HUMAN | | Bait Gene Name | EPN2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 636-640 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20383 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10567358 | | Comments | Asn-Pro-Phe motif (636-640) in human Epsin-2 that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15) |
Record No : 68 |
| Instance ID | 10384 | | Regular Expression | xNPFx | | Motif Instance | LNPFL | | Bait Uniprot Accession | Q13492 | | Bait Uniprot Identifier | PICAL_HUMAN | | Bait Gene Name | PICALM | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 436-440 | | Critical Residues | P2; P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | SPR | | Interaction ID | 20384 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12807910 | | Comments | Asn-Pro-Phe motif (436-440) in human AP180-2 (CALM) that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15) |
Record No : 69 |
| Instance ID | 10385 | | Regular Expression | xNPFx | | Motif Instance | PNPFG | | Bait Uniprot Accession | Q13492 | | Bait Uniprot Identifier | PICAL_HUMAN | | Bait Gene Name | PICALM | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 638-642 | | Critical Residues | P2; P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | SPR | | Interaction ID | 20385 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12807910 | | Comments | Asn-Pro-Phe motif (638-642) in human AP180-2 (CALM) that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15) |
Record No : 70 |
| Instance ID | 10386 | | Regular Expression | xNPFx | | Motif Instance | SNPFD | | Bait Uniprot Accession | Q8NDI1 | | Bait Uniprot Identifier | EHBP1_HUMAN | | Bait Gene Name | EHBP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 267-271 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20386 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14676205 | | Comments | Human EH domain protein 2 (EHD2) contains a C-terminal EH domain that interacts with the NPF repeat (267-271) in EHD2-binding protein 1 (EHBP1) and thereby links clathrin-mediated endocytosis to the actin cytoskeleton |
Record No : 71 |
| Instance ID | 10387 | | Regular Expression | xNPFx | | Motif Instance | LNPFG | | Bait Uniprot Accession | Q8NDI1 | | Bait Uniprot Identifier | EHBP1_HUMAN | | Bait Gene Name | EHBP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 278-282 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20387 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14676205 | | Comments | Human EH domain protein 2 (EHD2) contains a C-terminal EH domain that interacts with the NPF repeat (278-282) in EHD2-binding protein 1 (EHBP1) and thereby links clathrin-mediated endocytosis to the actin cytoskeleton |
Record No : 72 |
| Instance ID | 10388 | | Regular Expression | xNPFx | | Motif Instance | YNPFK | | Bait Uniprot Accession | Q8NDI1 | | Bait Uniprot Identifier | EHBP1_HUMAN | | Bait Gene Name | EHBP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 308-312 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20388 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14676205 | | Comments | Human EH domain protein 2 (EHD2) contains a C-terminal EH domain that interacts with the NPF repeat (308-312) in EHD2-binding protein 1 (EHBP1) and thereby links clathrin-mediated endocytosis to the actin cytoskeleton |
Record No : 73 |
| Instance ID | 10389 | | Regular Expression | xNPFx | | Motif Instance | LNPFD | | Bait Uniprot Accession | Q8NDI1 | | Bait Uniprot Identifier | EHBP1_HUMAN | | Bait Gene Name | EHBP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 320-324 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20389 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14676205 | | Comments | Human EH domain protein 2 (EHD2) contains a C-terminal EH domain that interacts with the NPF repeat (320-324) in EHD2-binding protein 1 (EHBP1) and thereby links clathrin-mediated endocytosis to the actin cytoskeleton |
Record No : 74 |
| Instance ID | 10390 | | Regular Expression | xNPFx | | Motif Instance | SNPFY | | Bait Uniprot Accession | Q8NDI1 | | Bait Uniprot Identifier | EHBP1_HUMAN | | Bait Gene Name | EHBP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 369-373 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20390 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14676205 | | Comments | Human EH domain protein 2 (EHD2) contains a C-terminal EH domain that interacts with the NPF repeat (369-373) in EHD2-binding protein 1 (EHBP1) and thereby links clathrin-mediated endocytosis to the actin cytoskeleton |
Record No : 75 |
| Instance ID | 10391 | | Regular Expression | xNPFx | | Motif Instance | SNPFL | | Bait Uniprot Accession | Q9Y6I3 | | Bait Uniprot Identifier | EPN1_HUMAN | | Bait Gene Name | EPN1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 501-505 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Far Western blotting; Competition binding | | Interaction ID | 20391 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10557078 | | Comments | The EH domain of POB1 (or REPS2) interacts directly with the region containing the NPF motif (501-505) of Epsin |
Record No : 76 |
| Instance ID | 10392 | | Regular Expression | xNPFx | | Motif Instance | TNPFQ | | Bait Uniprot Accession | Q9Y6I3 | | Bait Uniprot Identifier | EPN1_HUMAN | | Bait Gene Name | EPN1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 517-521 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Far Western blotting; Competition binding | | Interaction ID | 20392 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10557078 | | Comments | The EH domain of POB1 (or REPS2) interacts directly with the region containing the NPF motif (517-521) of Epsin |
Record No : 77 |
| Instance ID | 10393 | | Regular Expression | xNPFx | | Motif Instance | TNPFL | | Bait Uniprot Accession | Q9Y6I3 | | Bait Uniprot Identifier | EPN1_HUMAN | | Bait Gene Name | EPN1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 571-575 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Far Western blotting; Competition binding | | Interaction ID | 20393 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10557078 | | Comments | The EH domain of POB1 (or REPS2) interacts directly with the region containing the NPF motif (571-575) of Epsin |
Record No : 78 |
| Instance ID | 10394 | | Regular Expression | xNPFx | | Motif Instance | ANPFL | | Bait Uniprot Accession | Q24212 | | Bait Uniprot Identifier | STNB_DROME | | Bait Gene Name | stnB | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 2-6 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Far Western blotting | | Interaction ID | 20394 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15631619 | | Comments | The NPF motif (2-6) in Drosophila stoned-B protein (stnB) that has been found to be high-affinity binding motif for the EH domain of DAP-160 (intersectin) |
Record No : 79 |
| Instance ID | 10395 | | Regular Expression | xNPFx | | Motif Instance | ANPFL | | Bait Uniprot Accession | Q24212 | | Bait Uniprot Identifier | STNB_DROME | | Bait Gene Name | stnB | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 18-22 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Far Western blotting | | Interaction ID | 20395 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15631619 | | Comments | The NPF motif (18-22) in Drosophila stoned-B protein (stnB) that has been found to be high-affinity binding motif for the EH domain of DAP-160 (intersectin) |
Record No : 80 |
| Instance ID | 10396 | | Regular Expression | xNPFx | | Motif Instance | DNPFM | | Bait Uniprot Accession | Q24212 | | Bait Uniprot Identifier | STNB_DROME | | Bait Gene Name | stnB | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 32-36 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Far Western blotting | | Interaction ID | 20396 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15631619 | | Comments | The NPF motif (32-36) in Drosophila stoned-B protein (stnB) that has been found to be high-affinity binding motif for the EH domain of DAP-160 (intersectin) |
Record No : 81 |
| Instance ID | 10397 | | Regular Expression | xNPFx | | Motif Instance | SNPFA | | Bait Uniprot Accession | Q24212 | | Bait Uniprot Identifier | STNB_DROME | | Bait Gene Name | stnB | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 42-46 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Far Western blotting | | Interaction ID | 20397 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15631619 | | Comments | The NPF motif (42-46) in Drosophila stoned-B protein (stnB) that has been found to be high-affinity binding motif for the EH domain of DAP-160 (intersectin) |
Record No : 82 |
| Instance ID | 10398 | | Regular Expression | xNPFx | | Motif Instance | DNPFA | | Bait Uniprot Accession | Q24212 | | Bait Uniprot Identifier | STNB_DROME | | Bait Gene Name | stnB | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 209-213 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Far Western blotting | | Interaction ID | 20398 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15631619 | | Comments | The NPF motif (209-213) in Drosophila stoned-B protein (stnB) that has been found to be high-affinity binding motif for the EH domain of DAP-160 (intersectin) |
Record No : 83 |
| Instance ID | 10399 | | Regular Expression | xNPFx | | Motif Instance | ANPFA | | Bait Uniprot Accession | Q24212 | | Bait Uniprot Identifier | STNB_DROME | | Bait Gene Name | stnB | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 492-496 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Far Western blotting | | Interaction ID | 20399 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15631619 | | Comments | The NPF motif (492-496) in Drosophila stoned-B protein (stnB) that has been found to be high-affinity binding motif for the EH domain of DAP-160 (intersectin) |
Record No : 84 |
| Instance ID | 10400 | | Regular Expression | xNPFx | | Motif Instance | VNPFE | | Bait Uniprot Accession | Q24212 | | Bait Uniprot Identifier | STNB_DROME | | Bait Gene Name | stnB | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 672-676 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Far Western blotting | | Interaction ID | 20400 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15631619 | | Comments | The NPF motif (672-676) in Drosophila stoned-B protein (stnB) that has been found to be high-affinity binding motif for the EH domain of DAP-160 (intersectin) |
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