Query   'Elastin-binding domain of EBP'  matched   8 Records

Record No : 1

Instance ID11236
Regular ExpressionxGxxPG
Motif InstancePGAIPG
Bait Uniprot AccessionP15502
Bait Uniprot IdentifierELN_HUMAN
Bait Gene NameELN
Bait OrganismHomo sapiens (Human)
Sequence Position30-35
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureType VIII reverse beta-turn
Experimental Method(s)Sequence based prediction; Chemotaxis assay; Gelatin zymography; ELISA
Interaction ID21236
Interacting DomainElastin-binding domain of EBP
Disease Association(s)Emphysema; Aneurysm; Cancer
Inhibitor(s)Galactosugars
Reference(s)8388074, 8396888, 15148686, 11084020, 1848864, 8034752, 2550450, 11723829
CommentsThe 67-kD human elastin-binding protein (EBP) binds to a chemokinetic hexapeptide (30-35) from human Tropoelastin and mediates cell adhesion to elastin and elastin fiber assembly

Record No : 2

Instance ID11237
Regular ExpressionxGxxPG
Motif InstancePGAIPG
Bait Uniprot AccessionP15502
Bait Uniprot IdentifierELN_HUMAN
Bait Gene NameELN
Bait OrganismHomo sapiens (Human)
Sequence Position286-291
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureType VIII reverse beta-turn
Experimental Method(s)Sequence based prediction; Chemotaxis assay; Gelatin zymography; ELISA
Interaction ID21237
Interacting DomainElastin-binding domain of EBP
Disease Association(s)Emphysema; Aneurysm; Cancer
Inhibitor(s)Galactosugars
Reference(s)8388074, 8396888, 15148686, 11084020, 1848864, 8034752, 2550450, 11723829
CommentsThe 67-kD human elastin-binding protein (EBP) binds to a chemokinetic hexapeptide (286-291) from human Tropoelastin and mediates cell adhesion to elastin and elastin fiber assembly

Record No : 3

Instance ID11238
Regular ExpressionxGxxPG
Motif InstanceVGVAPG
Bait Uniprot AccessionP15502
Bait Uniprot IdentifierELN_HUMAN
Bait Gene NameELN
Bait OrganismHomo sapiens (Human)
Sequence Position506-511
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureType VIII reverse beta-turn
Experimental Method(s)NMR; CD; Fluorimetric measurements
Interaction ID21238
Interacting DomainElastin-binding domain of EBP
Disease Association(s)Emphysema; Aneurysm; Cancer
Inhibitor(s)Galactosugars
Reference(s)15148686, 19241470, 23166321, 1848864, 8034752, 2550450
CommentsThe 67-kD human elastin-binding protein (EBP) binds to a chemokinetic hexapeptide (506-511) from human Tropoelastin and mediates cell adhesion to elastin and elastin fiber assembly

Record No : 4

Instance ID11239
Regular ExpressionxGxxPG
Motif InstanceVGVAPG
Bait Uniprot AccessionP15502
Bait Uniprot IdentifierELN_HUMAN
Bait Gene NameELN
Bait OrganismHomo sapiens (Human)
Sequence Position512-517
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureType VIII reverse beta-turn
Experimental Method(s)NMR; CD; Fluorimetric measurements
Interaction ID21239
Interacting DomainElastin-binding domain of EBP
Disease Association(s)Emphysema; Aneurysm; Cancer
Inhibitor(s)Galactosugars
Reference(s)15148686, 19241470, 23166321, 1848864, 8034752, 2550450
CommentsThe 67-kD human elastin-binding protein (EBP) binds to a chemokinetic hexapeptide (512-517) from human Tropoelastin and mediates cell adhesion to elastin and elastin fiber assembly

Record No : 5

Instance ID11240
Regular ExpressionxGxxPG
Motif InstanceVGVAPG
Bait Uniprot AccessionP15502
Bait Uniprot IdentifierELN_HUMAN
Bait Gene NameELN
Bait OrganismHomo sapiens (Human)
Sequence Position518-523
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureType VIII reverse beta-turn
Experimental Method(s)NMR; CD; Fluorimetric measurements
Interaction ID21240
Interacting DomainElastin-binding domain of EBP
Disease Association(s)Emphysema; Aneurysm; Cancer
Inhibitor(s)Galactosugars
Reference(s)15148686, 19241470, 23166321, 1848864, 8034752, 2550450
CommentsThe 67-kD human elastin-binding protein (EBP) binds to a chemokinetic hexapeptide (518-523) from human Tropoelastin and mediates cell adhesion to elastin and elastin fiber assembly

Record No : 6

Instance ID11241
Regular ExpressionxGxxPG
Motif InstanceVGVAPG
Bait Uniprot AccessionP15502
Bait Uniprot IdentifierELN_HUMAN
Bait Gene NameELN
Bait OrganismHomo sapiens (Human)
Sequence Position542-547
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureType VIII reverse beta-turn
Experimental Method(s)NMR; CD; Fluorimetric measurements
Interaction ID21241
Interacting DomainElastin-binding domain of EBP
Disease Association(s)Emphysema; Aneurysm; Cancer
Inhibitor(s)Galactosugars
Reference(s)15148686, 19241470, 23166321, 1848864, 8034752, 2550450
CommentsThe 67-kD human elastin-binding protein (EBP) binds to a chemokinetic hexapeptide (542-547) from human Tropoelastin and mediates cell adhesion to elastin and elastin fiber assembly

Record No : 7

Instance ID11242
Regular ExpressionxGxxPG
Motif InstanceLGTIPG
Bait Uniprot AccessionP07942
Bait Uniprot IdentifierLAMB1_HUMAN
Bait Gene NameLAMB1
Bait OrganismHomo sapiens (Human)
Sequence Position463-468
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureType VIII reverse beta-turn
Experimental Method(s)Gelatin zymography; ELISA
Interaction ID21242
Interacting DomainElastin-binding domain of EBP
Disease Association(s)Unknown
Inhibitor(s)Galactosugars
Reference(s)15148686, 1848864, 2550450, 11723829
CommentsThe 67-kD human elastin-binding protein (EBP) binds to a hexapeptide motif from human Laminin subunit beta-1 (LAMB1)

Record No : 8

Instance ID11243
Regular ExpressionxGxxPG
Motif InstanceEGFEPG
Bait Uniprot AccessionP35555
Bait Uniprot IdentifierFBN1_HUMAN
Bait Gene NameFBN1
Bait OrganismHomo sapiens (Human)
Sequence Position2194-2199
Critical ResiduesP5
Motif PTM(s)Unknown
Secondary StructureType VIII reverse beta-turn
Experimental Method(s)Site-directed Mutagenesis; Chemotaxis assay
Interaction ID21243
Interacting DomainElastin-binding domain of EBP
Disease Association(s)Marfan syndrome
Inhibitor(s)Unknown
Reference(s)16442122, 17030689
CommentsThe 67-kD human elastin-binding protein (EBP) binds to a hexapeptide motif from human Fibrillin-1 (FBN1)




© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)