Query   'FG-GAP repeat'  matched   2 Records

Record No : 1

Instance ID10810
Regular ExpressionRGD
Motif InstanceRGD
Bait Uniprot AccessionP02751
Bait Uniprot IdentifierFINC_HUMAN
Bait Gene NameFN1
Bait OrganismHomo sapiens (Human)
Sequence Position1524-1526
Critical ResiduesP1; P3
Motif PTM(s)Unknown
Secondary StructureExtended conformation
Experimental Method(s)X-ray crystallography
Interaction ID20810
Interacting DomainFG-GAP repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)22451694
CommentsHuman Integrin alpha-5 is a major cellular receptor for the extracellular matrix protein fibronectin that binds to the RGD motif in Human Fibronectin (FN1)

Record No : 2

Instance ID10811
Regular ExpressionRGD
Motif InstanceRGD
Bait Uniprot AccessionP29788
Bait Uniprot IdentifierVTNC_MOUSE
Bait Gene NameVtn
Bait OrganismMus musculus (Mouse)
Sequence Position64-66
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP
Interaction ID20811
Interacting DomainFG-GAP repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)1703206
CommentsThe Integrin binding RGD motif in mouse Vitronectin (Vtn) that mediates binding to the mouse Vitronectin receptor subunit alpha/Integrin alpha-V (Itgav)


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)