Query   'Homeodomain'  matched   21 Records

Record No : 1

Instance ID11897
Regular Expression[FY]PWM[KR]
Motif InstanceFDWMK
Bait Uniprot AccessionP09022
Bait Uniprot IdentifierHXA1_MOUSE
Bait Gene NameHoxa1
Bait OrganismMus musculus (Mouse)
Sequence Position201-205
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21897
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxa1 that is essential for cooperative DNA binding with Pbx1

Record No : 2

Instance ID11898
Regular Expression[FY]PWM[KR]
Motif InstanceFDWMK
Bait Uniprot AccessionP17919
Bait Uniprot IdentifierHXB1_MOUSE
Bait Gene NameHoxb1
Bait OrganismMus musculus (Mouse)
Sequence Position176-180
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)X-ray crystallography; Mutational analysis
Interaction ID21898
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458, 10052460
CommentsThe highly conserved pentapeptide motif in mouse Hoxb1 that is essential for cooperative DNA binding with Pbx1

Record No : 3

Instance ID11899
Regular Expression[FY]PWM[KR]
Motif InstanceFEWMK
Bait Uniprot AccessionQ01822
Bait Uniprot IdentifierHXD1_MOUSE
Bait Gene NameHoxd1
Bait OrganismMus musculus (Mouse)
Sequence Position205-209
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21899
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxd1 that is essential for cooperative DNA binding with Pbx1

Record No : 4

Instance ID11900
Regular Expression[FY]PWM[KR]
Motif InstanceYPWMK
Bait Uniprot AccessionP31245
Bait Uniprot IdentifierHXA2_MOUSE
Bait Gene NameHoxa2
Bait OrganismMus musculus (Mouse)
Sequence Position97-101
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21900
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxa2 that is essential for cooperative DNA binding with Pbx1

Record No : 5

Instance ID11901
Regular Expression[FY]PWM[KR]
Motif InstanceFPWMK
Bait Uniprot AccessionP0C1T1
Bait Uniprot IdentifierHXB2_MOUSE
Bait Gene NameHoxb2
Bait OrganismMus musculus (Mouse)
Sequence Position93-97
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21901
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxb2 that is essential for cooperative DNA binding with Pbx1

Record No : 6

Instance ID11902
Regular Expression[FY]PWM[KR]
Motif InstanceFPWMK
Bait Uniprot AccessionP09026
Bait Uniprot IdentifierHXB3_MOUSE
Bait Gene NameHoxb3
Bait OrganismMus musculus (Mouse)
Sequence Position130-134
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21902
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxb3 that is essential for cooperative DNA binding with Pbx1

Record No : 7

Instance ID11903
Regular Expression[FY]PWM[KR]
Motif InstanceFPWMK
Bait Uniprot AccessionP09027
Bait Uniprot IdentifierHXD3_MOUSE
Bait Gene NameHoxd3
Bait OrganismMus musculus (Mouse)
Sequence Position162-166
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21903
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxd3 that is essential for cooperative DNA binding with Pbx1

Record No : 8

Instance ID11904
Regular Expression[FY]PWM[KR]
Motif InstanceYPWMK
Bait Uniprot AccessionP06798
Bait Uniprot IdentifierHXA4_MOUSE
Bait Gene NameHoxa4
Bait OrganismMus musculus (Mouse)
Sequence Position160-164
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21904
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxa4 that is essential for cooperative DNA binding with Pbx1

Record No : 9

Instance ID11905
Regular Expression[FY]PWM[KR]
Motif InstanceYPWMR
Bait Uniprot AccessionP10284
Bait Uniprot IdentifierHXB4_MOUSE
Bait Gene NameHoxb4
Bait OrganismMus musculus (Mouse)
Sequence Position141-145
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21905
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxb4 that is essential for cooperative DNA binding with Pbx1

Record No : 10

Instance ID11906
Regular Expression[FY]PWM[KR]
Motif InstanceYPWMK
Bait Uniprot AccessionQ08624
Bait Uniprot IdentifierHXC4_MOUSE
Bait Gene NameHoxc4
Bait OrganismMus musculus (Mouse)
Sequence Position136-140
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21906
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxc4 that is essential for cooperative DNA binding with Pbx1

Record No : 11

Instance ID11907
Regular Expression[FY]PWM[KR]
Motif InstanceYPWMK
Bait Uniprot AccessionP10628
Bait Uniprot IdentifierHXD4_MOUSE
Bait Gene NameHoxd4
Bait OrganismMus musculus (Mouse)
Sequence Position132-136
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21907
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxd4 that is essential for cooperative DNA binding with Pbx1

Record No : 12

Instance ID11908
Regular Expression[FY]PWM[KR]
Motif InstanceYPWMR
Bait Uniprot AccessionP09021
Bait Uniprot IdentifierHXA5_MOUSE
Bait Gene NameHoxa5
Bait OrganismMus musculus (Mouse)
Sequence Position177-181
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21908
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxa5 that is essential for cooperative DNA binding with Pbx1

Record No : 13

Instance ID11909
Regular Expression[FY]PWM[KR]
Motif InstanceFPWMR
Bait Uniprot AccessionP09079
Bait Uniprot IdentifierHXB5_MOUSE
Bait Gene NameHoxb5
Bait OrganismMus musculus (Mouse)
Sequence Position177-181
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21909
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxb5 that is essential for cooperative DNA binding with Pbx1

Record No : 14

Instance ID11910
Regular Expression[FY]PWM[KR]
Motif InstanceYPWMR
Bait Uniprot AccessionP02830
Bait Uniprot IdentifierHXA7_MOUSE
Bait Gene NameHoxa7
Bait OrganismMus musculus (Mouse)
Sequence Position119-123
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21910
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxa7 that is essential for cooperative DNA binding with Pbx1

Record No : 15

Instance ID11911
Regular Expression[FY]PWM[KR]
Motif InstanceYPWMR
Bait Uniprot AccessionP09024
Bait Uniprot IdentifierHXB7_MOUSE
Bait Gene NameHoxb7
Bait OrganismMus musculus (Mouse)
Sequence Position127-131
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21911
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxb7 that is essential for cooperative DNA binding with Pbx1

Record No : 16

Instance ID11912
Regular Expression[FY]PWM[KR]
Motif InstanceFPWMR
Bait Uniprot AccessionP09632
Bait Uniprot IdentifierHXB8_MOUSE
Bait Gene NameHoxb8
Bait OrganismMus musculus (Mouse)
Sequence Position135-139
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21912
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxb8 that is essential for cooperative DNA binding with Pbx1

Record No : 17

Instance ID11913
Regular Expression[FY]PWM[KR]
Motif InstanceFPWMR
Bait Uniprot AccessionP09025
Bait Uniprot IdentifierHXC8_MOUSE
Bait Gene NameHoxc8
Bait OrganismMus musculus (Mouse)
Sequence Position139-143
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21913
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxc8 that is essential for cooperative DNA binding with Pbx1

Record No : 18

Instance ID11914
Regular Expression[FY]PWM[KR]
Motif InstanceFPWMR
Bait Uniprot AccessionP23463
Bait Uniprot IdentifierHXD8_MOUSE
Bait Gene NameHoxd8
Bait OrganismMus musculus (Mouse)
Sequence Position184-188
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21914
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)7565734, 8600458
CommentsThe highly conserved pentapeptide motif in mouse Hoxd8 that is essential for cooperative DNA binding with Pbx1

Record No : 19

Instance ID11915
Regular Expression[FY]PWM[KR]
Motif InstanceFPWMK
Bait Uniprot AccessionP52947
Bait Uniprot IdentifierPDX1_RAT
Bait Gene NamePdx1
Bait OrganismRattus norvegicus (Rat)
Sequence Position119-123
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21915
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11158595
CommentsThe highly conserved pentapeptide motif in rat homeobox factor Pdx1 that promotes heterodimer formation with the ubiquitous homeodomain protein PBX

Record No : 20

Instance ID11916
Regular Expression[FY]PWM[KR]
Motif InstanceFPWMK
Bait Uniprot AccessionP52945
Bait Uniprot IdentifierPDX1_HUMAN
Bait Gene NamePDX1
Bait OrganismHomo sapiens (Human)
Sequence Position119-123
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21916
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)8524276
CommentsThe highly conserved pentapeptide motif in human pancreatic islet factor STF-1 that promotes heterodimer formation with the ubiquitous homeodomain protein PBX for cooperative binding to to a regulatory element in the somatostatin promoter

Record No : 21

Instance ID11917
Regular Expression[FY]PWM[KR]
Motif InstanceYPWMA
Bait Uniprot AccessionP83949
Bait Uniprot IdentifierUBX_DROME
Bait Gene NameUbx
Bait OrganismDrosophila melanogaster (Fruit fly)
Sequence Position240-244
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureType I reverse turn
Experimental Method(s)X-ray crystallography
Interaction ID21917
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10067897
CommentsThe highly conserved pentapeptide motif in Drosophila homeotic protein Ultrabithorax that forms a reverse turn and inserts into a hydrophobic pocket on the Drosophila Homeobox protein Extradenticle homeodomain surface to form a cooperative heterodimer and gain affinity and specificity




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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)