Query 'Ligand-binding domain of nuclear hormone receptor' matched 24 Records
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Record No : 1 |
| Instance ID | 10556 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | VLRKLLK | | Bait Uniprot Accession | Q90ZL7 | | Bait Uniprot Identifier | Q90ZL7_DANRE | | Bait Gene Name | prox1a | | Bait Organism | Danio rerio (Zebrafish) (Brachydanio rerio) | | Sequence Position | 69-75 | | Critical Residues | P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Site-directed mutagenesis; Y2H | | Interaction ID | 20556 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14517294 | | Comments | The NR box motif (LXXLL) of Zebrafish Prox1, a prospero-related homeodomain protein, interacts with and modulates the transcriptional activity of Ff1b (nr5a4), the zebrafish homologue of SF-1 |
Record No : 2 |
| Instance ID | 10557 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | SLSQLLD | | Bait Uniprot Accession | Q9JL19 | | Bait Uniprot Identifier | NCOA6_MOUSE | | Bait Gene Name | Ncoa6 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 1494-1500 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 20557 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12724417 | | Comments | The NR box motif (LXXLL) of mouse Nuclear receptor coactivator 6 (Ncoa6)/Activating signal cointegrator 2 (ASC-2) that interacts with Liver X receptor alpha, enabling ASC-2 to act as a physiologically important transcriptional coactivator of LXRalpha in mice |
Record No : 3 |
| Instance ID | 10558 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | ELKALLQ | | Bait Uniprot Accession | Q9UQ80 | | Bait Uniprot Identifier | PA2G4_HUMAN | | Bait Gene Name | PA2G4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 353-359 | | Critical Residues | P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation analysis; Pull down(GST tag) | | Interaction ID | 20558 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 12165860 | | Comments | The NR box motif (LXXLL) of human ErbB-3 binding protein (EBP1)/ Proliferation-associated protein 2G4 (PA2G4), that is necessary for binding the human Androgen receptor (AR) |
Record No : 4 |
| Instance ID | 10559 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | LLASLLQ | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 132-138 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 20559 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902 | | Comments | The NR box motif (132-138) of human Nuclear receptor-interacting protein 1 (NRIP1)/ Nuclear factor RIP140 that is necessary for binding the human Estrogen receptor (ESR) |
Record No : 5 |
| Instance ID | 10560 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | HLKTLLK | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 184-190 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 20560 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902 | | Comments | The NR box motif (184-190) of human Nuclear receptor-interacting protein 1 (NRIP1)/ Nuclear factor RIP140 that is necessary for binding the human Estrogen receptor (ESR) |
Record No : 6 |
| Instance ID | 10561 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | YLEGLLM | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 20-26 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 20561 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902 | | Comments | The NR box motif (20-26) of human Nuclear receptor-interacting protein 1 (NRIP1)/ Nuclear factor RIP140 that is necessary for binding the human Estrogen receptor (ESR) |
Record No : 7 |
| Instance ID | 10562 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | QLALLLS | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 265-271 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 20562 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902 | | Comments | The NR box motif (265-271) of human Nuclear receptor-interacting protein 1 (NRIP1)/ Nuclear factor RIP140 that is necessary for binding the human Estrogen receptor (ESR) |
Record No : 8 |
| Instance ID | 10563 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | VLQLLLG | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 712-718 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 20563 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902 | | Comments | The NR box motif (712-718) of human Nuclear receptor-interacting protein 1 (NRIP1)/ Nuclear factor RIP140 that is necessary for binding the human Estrogen receptor (ESR) |
Record No : 9 |
| Instance ID | 10564 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | LLQLLLG | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 500-506 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 20564 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902 | | Comments | The NR box motif (500-506) of human Nuclear receptor-interacting protein 1 (NRIP1)/ Nuclear factor RIP140 that is necessary for binding the human Estrogen receptor (ESR) |
Record No : 10 |
| Instance ID | 10565 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | LLSRLLR | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 818-824 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 20565 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902 | | Comments | The NR box motif (818-824) of human Nuclear receptor-interacting protein 1 (NRIP1)/ Nuclear factor RIP140 that is necessary for binding the human Estrogen receptor (ESR) |
Record No : 11 |
| Instance ID | 10566 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | VLKQLLL | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 935-941 | | Critical Residues | P2; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H; Mutation analysis | | Interaction ID | 20566 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902 | | Comments | The NR box motif (935-941) of human Nuclear receptor-interacting protein 1 (NRIP1)/ Nuclear factor RIP140 that is necessary for binding the human Estrogen receptor (ESR) |
Record No : 12 |
| Instance ID | 10567 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | ILHRLLQ | | Bait Uniprot Accession | Q15596 | | Bait Uniprot Identifier | NCOA2_HUMAN | | Bait Gene Name | NCOA2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 689-695 | | Critical Residues | P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | X-ray crystallography; Affinity chromatography technology; Mutation analysis | | Interaction ID | 20567 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11937504, 9430642 | | Comments | The NR box motif (689-695) of human Nuclear receptor coactivator 2 (NCOA2)/ Transcriptional intermediary factor 2 (TIF2) that is necessary for binding the human Glucocorticoid receptor (GRL/NR3C1) |
Record No : 13 |
| Instance ID | 10568 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | LLLHLLK | | Bait Uniprot Accession | P48552 | | Bait Uniprot Identifier | NRIP1_HUMAN | | Bait Gene Name | NRIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 379-385 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | X-ray crystallography; Y2H | | Interaction ID | 20568 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16990259, 9192902 | | Comments | The NR box motif (379-385) of human Nuclear receptor-interacting protein 1 (NRIP1)/ Nuclear factor RIP140 that is necessary for binding the human Estrogen receptor (ESR) |
Record No : 14 |
| Instance ID | 10569 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | LLKKLLL | | Bait Uniprot Accession | Q9UBK2 | | Bait Uniprot Identifier | PRGC1_HUMAN | | Bait Gene Name | PPARGC1A | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 143-149 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | X-ray crystallography | | Interaction ID | 20569 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18469005, 12502716 | | Comments | The functional interaction between the human Peroxisome proliferator-activated receptor gamma (PPARG) and its coactivator PPAR-gamma coactivator 1-alpha (PPARGC1A/PGC-1) is mediated by the LXXLL motif of PGC-1 |
Record No : 15 |
| Instance ID | 10570 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | LLRYLLD | | Bait Uniprot Accession | Q15596 | | Bait Uniprot Identifier | NCOA2_HUMAN | | Bait Gene Name | NCOA2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 744-750 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | X-ray crystallography | | Interaction ID | 20570 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12151000 | | Comments | The NR box motif (744-750) of human Nuclear receptor coactivator 2 (NCOA2)/ Transcriptional intermediary factor 2 (TIF2) that is necessary for binding the human Glucocorticoid receptor (GRL/NR3C1) |
Record No : 16 |
| Instance ID | 10571 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | RLCRLLR | | Bait Uniprot Accession | O43593 | | Bait Uniprot Identifier | HAIR_HUMAN | | Bait Gene Name | HR | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 565-571 | | Critical Residues | P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation analysis; Y2H; Co-IP; Pull down(GST tag) | | Interaction ID | 20571 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12215540 | | Comments | The NR box motif (565-571) of human product of the thyroid hormone-regulated mammalian gene hairless (HR) that is necessary for binding the human Nuclear receptor ROR-alpha (RORA) |
Record No : 17 |
| Instance ID | 10572 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | SLCELLA | | Bait Uniprot Accession | O43593 | | Bait Uniprot Identifier | HAIR_HUMAN | | Bait Gene Name | HR | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 757-763 | | Critical Residues | P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation analysis; Y2H; Co-IP; Pull down(GST tag) | | Interaction ID | 20572 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12215540 | | Comments | The NR box motif (757-763) of human product of the thyroid hormone-regulated mammalian gene hairless (HR) that is necessary for binding the human Nuclear receptor ROR-alpha (RORA) |
Record No : 18 |
| Instance ID | 10573 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | ILTSLLQ | | Bait Uniprot Accession | Q15648 | | Bait Uniprot Identifier | MED1_HUMAN | | Bait Gene Name | MED1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 603-609 | | Critical Residues | P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 20573 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12556447 | | Comments | The NR box motif (603-609) of human Mediator complex subunit 1 (MED1/TRAP220) that is necessary for binding the human Peroxisome proliferator-activated receptor gamma (PPARG) |
Record No : 19 |
| Instance ID | 10574 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | QLVLLLH | | Bait Uniprot Accession | Q92793 | | Bait Uniprot Identifier | CBP_HUMAN | | Bait Gene Name | CREBBP | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 357-363 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 20574 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902 | | Comments | The NR box motif (357-363) of human CREB-binding protein (CREBBP/CBP) that is necessary for binding the human Estrogen receptor (ESR) |
Record No : 20 |
| Instance ID | 10575 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | QLSELLR | | Bait Uniprot Accession | Q92793 | | Bait Uniprot Identifier | CBP_HUMAN | | Bait Gene Name | CREBBP | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 69-75 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 20575 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9192902 | | Comments | The NR box motif (69-75) of human CREB-binding protein (CREBBP/CBP) that is necessary for binding the human Estrogen receptor (ESR) |
Record No : 21 |
| Instance ID | 10576 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | KLLQLLT | | Bait Uniprot Accession | Q15596 | | Bait Uniprot Identifier | NCOA2_HUMAN | | Bait Gene Name | NCOA2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 640-646 | | Critical Residues | P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Affinity chromatography technology; Mutation analysis | | Interaction ID | 20576 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9430642 | | Comments | The NR box motif (640-646) of human Nuclear receptor coactivator 2 (NCOA2)/ Transcriptional intermediary factor 2 (TIF2) that is necessary for binding the human Glucocorticoid receptor (GRL/NR3C1) |
Record No : 22 |
| Instance ID | 10577 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | MLMNLLK | | Bait Uniprot Accession | Q15648 | | Bait Uniprot Identifier | MED1_HUMAN | | Bait Gene Name | MED1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 644-650 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | X-ray crystallography | | Interaction ID | 20577 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15065852 | | Comments | The NR box motif (644-650) of human Mediator complex subunit 1 (MED1/TRAP220) that is necessary for binding the rat Vitamin D3 receptor (Vdr) |
Record No : 23 |
| Instance ID | 10578 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | RLQKLLK | | Bait Uniprot Accession | Q16881 | | Bait Uniprot Identifier | TRXR1_HUMAN | | Bait Gene Name | TXNRD1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 46-52 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Pull down(GST tag); Colocalization(Confocal microscopy); Competition binding | | Interaction ID | 20578 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15199063 | | Comments | The NR box motif of human Thioredoxin reductase TR1 (TXNRD1/GRIM12) that is necessary for binding the human Estrogen receptor (ESR1) |
Record No : 24 |
| Instance ID | 10579 | | Regular Expression | [^P]L[^P][^P]LL[^P] | | Motif Instance | RLQKLLK | | Bait Uniprot Accession | Q16881 | | Bait Uniprot Identifier | TRXR1_HUMAN | | Bait Gene Name | TXNRD1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 46-52 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Pull down(GST tag); Colocalization(Confocal microscopy); Competition binding | | Interaction ID | 20579 | | Interacting Domain | Ligand-binding domain of nuclear hormone receptor | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15199063 | | Comments | The NR box motif of human Thioredoxin reductase TR1 (TXNRD1/GRIM12) that is necessary for binding the human Estrogen receptor beta (ESR2) |
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