Query 'MLLE domain' matched 26 Records
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Record No : 1 |
| Instance ID | 10585 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | SNLNPNAKEFVPG | | Bait Uniprot Accession | Q9BPZ3 | | Bait Uniprot Identifier | PAIP2_HUMAN | | Bait Gene Name | PAIP2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 109-121 | | Critical Residues | P3; P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Beta turn | | Experimental Method(s) | Co-IP; SPR; ITC; NMR; Mutation analysis; Pull down; X-ray crystallography | | Interaction ID | 20585 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16601676, 14685257, 20096703 | | Comments | The PABP-interacting motif 2 (PAM2) in human PABP-interacting protein 2 (PAIP2) that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) |
Record No : 2 |
| Instance ID | 10586 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | SVLNPMADEFVPR | | Bait Uniprot Accession | Q9VG13 | | Bait Uniprot Identifier | Q9VG13_DROME | | Bait Gene Name | Paip2 | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 103-115 | | Critical Residues | P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Beta turn | | Experimental Method(s) | Far Western blotting; Co-IP; Pull down | | Interaction ID | 20586 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14729960 | | Comments | The PABP-interacting motif 2 (PAM2) in the Drosophila melanogaster Paip2 (dPaip2) that mediates binding to the MLLE domain of Drosophila Polyadenylate-binding protein (pAbp) |
Record No : 3 |
| Instance ID | 10587 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | SKLSVNAPEFYPS | | Bait Uniprot Accession | Q9H074 | | Bait Uniprot Identifier | PAIP1_HUMAN | | Bait Gene Name | PAIP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 126-138 | | Critical Residues | P3; P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Beta turn | | Experimental Method(s) | ITC; NMR; SPR; Pull down; Mutation analysis; Far Western blotting; Co-IP | | Interaction ID | 20587 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16554297, 14685257, 11997512 | | Comments | The PABP-interacting motif 2 (PAM2) in human PABP-interacting protein 1 (PAIP1) that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) |
Record No : 4 |
| Instance ID | 10588 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | SNLNPDAKEFIPG | | Bait Uniprot Accession | Q9ULR5 | | Bait Uniprot Identifier | PAI2B_HUMAN | | Bait Gene Name | PAIP2B | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 108-120 | | Critical Residues | P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Beta turn | | Experimental Method(s) | Pull down; Far Western blotting; Co-IP | | Interaction ID | 20588 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16804161 | | Comments | The PABP-interacting motif 2 (PAM2) in human PABP-interacting protein 2B (PAIP2B) that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) |
Record No : 5 |
| Instance ID | 10589 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | STLNPNAKEFNPR | | Bait Uniprot Accession | Q99700 | | Bait Uniprot Identifier | ATX2_HUMAN | | Bait Gene Name | ATXN2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 912-924 | | Critical Residues | P3; P5; P7; P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Beta turn | | Experimental Method(s) | ITC; NMR; SPR; X-ray crystallography | | Interaction ID | 20589 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16554297, 20181956 | | Comments | The PABP-interacting motif 2 (PAM2) in human Ataxin-2 (ATXN2) that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) |
Record No : 6 |
| Instance ID | 10590 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | HVLNPSAKPFTPR | | Bait Uniprot Accession | Q8SWR8 | | Bait Uniprot Identifier | ATX2_DROME | | Bait Gene Name | Atx2 | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 857-869 | | Critical Residues | P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Co-IP | | Interaction ID | 20590 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16835262 | | Comments | The PABP-interacting motif 2 (PAM2) in the Drosophila melanogaster Ataxin-2 homolog (Datx2) that mediates binding to the MLLE domain of Drosophila Polyadenylate-binding protein (pAbp) |
Record No : 7 |
| Instance ID | 10591 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | TGLNPNAKVWQEI | | Bait Uniprot Accession | Q71RC2 | | Bait Uniprot Identifier | LARP4_HUMAN | | Bait Gene Name | LARP4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 13-25 | | Critical Residues | P3; P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Beta turn | | Experimental Method(s) | Mutation analysis; ITC; X-ray crystallography | | Interaction ID | 20591 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 21098120 | | Comments | The PABP-interacting motif 2 (PAM2) in human La-related protein 4 (LARP4) that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) |
Record No : 8 |
| Instance ID | 10592 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | SELNPNAEVWGAP | | Bait Uniprot Accession | Q92615 | | Bait Uniprot Identifier | LAR4B_HUMAN | | Bait Gene Name | LARP4B | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 54-66 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down(GST tag) | | Interaction ID | 20592 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20573744 | | Comments | The PABP-interacting motif 2 (PAM2) in human La-related protein 4B (LARP4B) that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) |
Record No : 9 |
| Instance ID | 10593 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | SKLNPNAPLFIPA | | Bait Uniprot Accession | Q6ELF8 | | Bait Uniprot Identifier | Q6ELF8_CUCSA | | Bait Gene Name | Not Available | | Bait Organism | Cucumis sativus (Cucumber) | | Sequence Position | 10-22 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20593 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15159636 | | Comments | The PABP-interacting motif 2 (PAM2) in cucumber Poly(A)-binding protein C-terminal interacting protein 243 (PCI243) that mediates binding to the MLLE domain of cucumber Poly(A)-binding protein |
Record No : 10 |
| Instance ID | 10594 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | STLNPDAPLFIPA | | Bait Uniprot Accession | Q39096 | | Bait Uniprot Identifier | ERD15_ARATH | | Bait Gene Name | ERD15 | | Bait Organism | Arabidopsis thaliana (Mouse-ear cress) | | Sequence Position | 9-21 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 20594 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15650869 | | Comments | The PABP-interacting motif 2 (PAM2) in Arabidopsis thaliana PAM2-containing protein CID1 (or ERD15) that mediates binding to the MLLE domain of Arabidopsis Polyadenylate-binding protein 2 (PAB2) |
Record No : 11 |
| Instance ID | 10595 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | RKLNVNAKPFVPN | | Bait Uniprot Accession | Q8IYD1 | | Bait Uniprot Identifier | ERF3B_HUMAN | | Bait Gene Name | GSPT2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 50-62 | | Critical Residues | P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Beta turn | | Experimental Method(s) | SPR; ITC; Co-IP; X-ray crystallography | | Interaction ID | 20595 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14685257, 18056425, 16554297, 20418951 | | Comments | The PAM2 motif (50-62) in human Eukaryotic peptide chain release factor subunit 3b (ERF3B)/ G1 to S phase transition protein 2 homolog (GSPT2) that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) |
Record No : 12 |
| Instance ID | 10596 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | FVPNVHAAEFVPS | | Bait Uniprot Accession | Q8IYD1 | | Bait Uniprot Identifier | ERF3B_HUMAN | | Bait Gene Name | GSPT2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 59-71 | | Critical Residues | P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Beta turn | | Experimental Method(s) | SPR; ITC; Co-IP; X-ray crystallography | | Interaction ID | 20596 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14685257, 18056425, 16554297, 20418951 | | Comments | The PAM2 motif (59-71) in human Eukaryotic peptide chain release factor subunit 3b (ERF3B)/ G1 to S phase transition protein 2 homolog (GSPT2) that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) |
Record No : 13 |
| Instance ID | 10597 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | FKFNTDAAEFIPQ | | Bait Uniprot Accession | Q12986 | | Bait Uniprot Identifier | NFX1_HUMAN | | Bait Gene Name | NFX1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 11-23 | | Critical Residues | P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Pull down; Co-IP; Mass spectrometry; Affinity chromatography technology | | Interaction ID | 20597 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17267499 | | Comments | Human cytoplasmic Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) interacts with NFX1-123, a splice variant of Transcriptional repressor NFX1, through its N-terminal PAM2 motif, and this interaction is critical to hTERT regulation in HPV16 E6-expressing epithelial cells |
Record No : 14 |
| Instance ID | 10598 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | FKFNTDAAEFIPQ | | Bait Uniprot Accession | Q12986 | | Bait Uniprot Identifier | NFX1_HUMAN | | Bait Gene Name | NFX1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 11-23 | | Critical Residues | P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Pull down; Co-IP; Mass spectrometry; Affinity chromatography technology | | Interaction ID | 20598 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17267499 | | Comments | Human cytoplasmic Polyadenylate-binding protein 4 (PABP4/PABPC4) interacts with NFX1-123, a splice variant of Transcriptional repressor NFX1, through its N-terminal PAM2 motif, and this interaction is critical to hTERT regulation in HPV16 E6-expressing epithelial cells |
Record No : 15 |
| Instance ID | 10599 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | STLNPQAPEFILG | | Bait Uniprot Accession | Q14694 | | Bait Uniprot Identifier | UBP10_HUMAN | | Bait Gene Name | USP10 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 81-93 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | SPR | | Interaction ID | 20599 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16554297 | | Comments | The MLLE/PABC domain of human Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) binds to the N-terminal PAM2 motif of human Ubiquitin carboxyl-terminal hydrolase 10 (USP10) |
Record No : 16 |
| Instance ID | 10600 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | STLNPQAPEFILG | | Bait Uniprot Accession | Q14694 | | Bait Uniprot Identifier | UBP10_HUMAN | | Bait Gene Name | USP10 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 81-93 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | ITC | | Interaction ID | 20600 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16554297 | | Comments | The MLLE/PABC domain of rat E3 ubiquitin-protein ligase Ubr5 binds to the N-terminal PAM2 motif of human Ubiquitin carboxyl-terminal hydrolase 10 (USP10) |
Record No : 17 |
| Instance ID | 10601 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | LQLNPAAREFKPD | | Bait Uniprot Accession | P53804 | | Bait Uniprot Identifier | TTC3_HUMAN | | Bait Gene Name | TTC3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1205-1217 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | SPR | | Interaction ID | 20601 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16554297 | | Comments | The MLLE/PABC domain of human Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) binds to the N-terminal PAM2 motif of human E3 ubiquitin-protein ligase TTC3 |
Record No : 18 |
| Instance ID | 10602 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | LQLNPAAREFKPD | | Bait Uniprot Accession | P53804 | | Bait Uniprot Identifier | TTC3_HUMAN | | Bait Gene Name | TTC3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1205-1217 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | ITC | | Interaction ID | 20602 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16554297 | | Comments | The MLLE/PABC domain of rat E3 ubiquitin-protein ligase Ubr5 binds to the N-terminal PAM2 motif of human E3 ubiquitin-protein ligase TTC3 |
Record No : 19 |
| Instance ID | 10603 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | SQLNPNAVAFVPG | | Bait Uniprot Accession | P23226 | | Bait Uniprot Identifier | MA205_DROME | | Bait Gene Name | Map205 | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 234-246 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | SPR | | Interaction ID | 20603 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16554297 | | Comments | The MLLE/PABC domain of human Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) binds to the N-terminal PAM2 motif of Drosophila microtubule-associated protein Map205 |
Record No : 20 |
| Instance ID | 10604 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | SQLNPNAVAFVPG | | Bait Uniprot Accession | P23226 | | Bait Uniprot Identifier | MA205_DROME | | Bait Gene Name | Map205 | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 234-246 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | NMR; ITC | | Interaction ID | 20604 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16554297 | | Comments | The MLLE/PABC domain of rat E3 ubiquitin-protein ligase Ubr5 binds to the N-terminal PAM2 motif of Drosophila microtubule-associated protein Map205 |
Record No : 21 |
| Instance ID | 10605 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | SALSPNAKEFIFP | | Bait Uniprot Accession | P50616 | | Bait Uniprot Identifier | TOB1_HUMAN | | Bait Gene Name | TOB1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 265-277 | | Critical Residues | P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Pull down; Mutation analysis; Co-IP; ITC; NMR | | Interaction ID | 20605 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17785442, 18056425, 20595394 | | Comments | The PAM2 motif (265-277) in human TOB1, an antiproliferative transcription factor, that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) |
Record No : 22 |
| Instance ID | 10606 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | SQLSPNAKEFVYN | | Bait Uniprot Accession | Q14106 | | Bait Uniprot Identifier | TOB2_HUMAN | | Bait Gene Name | TOB2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 251-263 | | Critical Residues | P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Pull down; Mutation analysis; SPR; ITC | | Interaction ID | 20606 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17785442, 16554297 | | Comments | The PAM2 motif (251-263) in human TOB2 that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) |
Record No : 23 |
| Instance ID | 10607 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | SSFNPDAQVFVPI | | Bait Uniprot Accession | Q14106 | | Bait Uniprot Identifier | TOB2_HUMAN | | Bait Gene Name | TOB2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 131-143 | | Critical Residues | P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Pull down; Mutation analysis; SPR; ITC | | Interaction ID | 20607 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17785442, 16554297 | | Comments | The PAM2 motif (131-143) in human TOB2 that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) |
Record No : 24 |
| Instance ID | 10608 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | QTPNPTASEFIPK | | Bait Uniprot Accession | Q58A45 | | Bait Uniprot Identifier | PAN3_HUMAN | | Bait Gene Name | PAN3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 284-296 | | Critical Residues | P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Co-IP; Pull down; ITC; NMR | | Interaction ID | 20608 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18056425, 17595167 | | Comments | The PAM2 motif in human PAB-dependent poly(A)-specific ribonuclease subunit PAN3 that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) |
Record No : 25 |
| Instance ID | 10609 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | SMLNPNAPLFVPM | | Bait Uniprot Accession | Q6ELF9 | | Bait Uniprot Identifier | Q6ELF9_CUCSA | | Bait Gene Name | Not Available | | Bait Organism | Cucumis sativus (Cucumber) | | Sequence Position | 14-26 | | Critical Residues | P3; P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutation analysis | | Interaction ID | 20609 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15159636 | | Comments | The PABP-interacting motif 2 (PAM2) in cucumber Poly(A)-binding protein C-terminal interacting protein 6 (PCI6) that mediates binding of proteins to the MLLE domain of cucumber Poly(A)-binding protein |
Record No : 26 |
| Instance ID | 10610 | | Regular Expression | xx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x | | Motif Instance | NSFNPEAQVFMPI | | Bait Uniprot Accession | P50616 | | Bait Uniprot Identifier | TOB1_HUMAN | | Bait Gene Name | TOB1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 130-142 | | Critical Residues | P10 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Pull down; Mutation analysis; ITC; NMR | | Interaction ID | 20610 | | Interacting Domain | MLLE domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17785442, 20595394 | | Comments | The PAM2 motif (130-142) in human TOB1, an antiproliferative transcription factor, that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2) |
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