Query 'PDZ domain' matched 274 Records
|
Record No : 1 |
| Instance ID | 10626 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | TNDSLL | | Bait Uniprot Accession | P07550 | | Bait Uniprot Identifier | ADRB2_HUMAN | | Bait Gene Name | ADRB2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 408-413 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Far Western blotting; Mutation analysis; X-ray crystallography | | Interaction ID | 20626 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11882663 | | Comments | The amino-terminal PDZ domain of human Na(+)/H(+) exchange regulatory cofactor NHERF1 (SLC9A3R1), referred to as PDZ1, binds with high affinity to the C-terminal PDZ domain-binding motif of human Beta-2 adrenergic receptor |
Record No : 2 |
| Instance ID | 10627 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | AEDSFL | | Bait Uniprot Accession | P09619 | | Bait Uniprot Identifier | PGFRB_HUMAN | | Bait Gene Name | PDGFRB | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1101-1106 | | Critical Residues | P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Far Western blotting; Mutation analysis; X-ray crystallography | | Interaction ID | 20627 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11882663 | | Comments | The amino-terminal PDZ domain of human Na(+)/H(+) exchange regulatory cofactor NHERF1 (SLC9A3R1), referred to as PDZ1, binds with high affinity to the C-terminal PDZ domain-binding motif of human Platelet-derived growth factor receptor beta |
Record No : 3 |
| Instance ID | 10628 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | LFSTEV | | Bait Uniprot Accession | P11274 | | Bait Uniprot Identifier | BCR_HUMAN | | Bait Gene Name | BCR | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1266-1271 | | Critical Residues | P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | NMR | | Interaction ID | 20628 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17473018 | | Comments | The PDZ domain of human AF-6/MLLT4 binds to the C-terminal PDZ domain-binding motif of human Breakpoint cluster region protein (BCR) efficiently after phosphorylation of AF-6 by the BCR kinase |
Record No : 4 |
| Instance ID | 10629 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | LEITEL | | Bait Uniprot Accession | Q9H251 | | Bait Uniprot Identifier | CAD23_HUMAN | | Bait Gene Name | CDH23 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 3349-3354 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | NMR; Pull down(GST tag); Western blot | | Interaction ID | 20629 | | Interacting Domain | PDZ domain | | Disease Association(s) | Usher's Syndrome | | Inhibitor(s) | Unknown | | Reference(s) | 19297620 | | Comments | The second PDZ Domain of Harmonin (USH1C) specifically interacts with the C-terminal class 1 PDZ domain-binding motif of human Cadherin-23 |
Record No : 5 |
| Instance ID | 10630 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | WFDTDL | | Bait Uniprot Accession | P35222 | | Bait Uniprot Identifier | CTNB1_HUMAN | | Bait Gene Name | CTNNB1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 776-781 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | ITC; X-ray crystallography | | Interaction ID | 20630 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18835279 | | Comments | C-terminal class 1 PDZ-binding motif in human Beta-catenin that binds to the PDZ domain of mouse Tax-interacting protein-1 (TIP-1)/ Tax1-binding protein 3 (Tax1bp3) |
Record No : 6 |
| Instance ID | 10631 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | YKQTSV | | Bait Uniprot Accession | Q792Q4 | | Bait Uniprot Identifier | CRIPT_RAT | | Bait Gene Name | Cript | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 96-101 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography | | Interaction ID | 20631 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8674113 | | Comments | C-terminal class 1 PDZ-binding motif in rat Cysteine-rich PDZ-binding protein (Cript) that binds to the third PDZ domain of rat Dlg4 or Psd95 |
Record No : 7 |
| Instance ID | 10632 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | KLMTTV | | Bait Uniprot Accession | Q8QG92 | | Bait Uniprot Identifier | DCT1B_XENLA | | Bait Gene Name | dact1-b | | Bait Organism | Xenopus laevis (African clawed frog) | | Sequence Position | 819-824 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography; Pull down(GST tag); Y2H; Mutation analysis | | Interaction ID | 20632 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11970895 | | Comments | C-terminal class 1 PDZ-binding motif in Xenopus Dapper (Dpr) that mediates its interaction with the Xenopus Dsh (XDsh)/ dishevelled homolog dvl2 |
Record No : 8 |
| Instance ID | 10633 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | GYSTRL | | Bait Uniprot Accession | Q13268 | | Bait Uniprot Identifier | DHRS2_HUMAN | | Bait Gene Name | DHRS2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 253-258 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography | | Interaction ID | 20633 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17384233 | | Comments | C-terminal class 1 PDZ-binding motif in human Dicarbonyl reductase HEP27 or DHRS2 that binds to the PDZ domain of human Na(+)/H(+) exchange regulatory cofactor NHERF2 (SLC9A3R2) |
Record No : 9 |
| Instance ID | 10634 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | EAQTRL | | Bait Uniprot Accession | P97836 | | Bait Uniprot Identifier | DLGP1_RAT | | Bait Gene Name | Dlgap1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 987-992 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography | | Interaction ID | 20634 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12954649 | | Comments | C-terminal class 1 PDZ-binding motif in rat Dlgap1/Gkap that binds to the rat Shank1 PDZ domain |
Record No : 10 |
| Instance ID | 10635 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | QDGTEV | | Bait Uniprot Accession | Q86XX4 | | Bait Uniprot Identifier | FRAS1_HUMAN | | Bait Gene Name | FRAS1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 4002-4007 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Fluorescence polarization spectroscopy; X-ray crystallography | | Interaction ID | 20635 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18155042 | | Comments | C-terminal class 1 PDZ-binding motif in human Extracellular matrix protein FRAS1 that binds to the rat Grip1 PDZ12 domain |
Record No : 11 |
| Instance ID | 10636 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | EEESQL | | Bait Uniprot Accession | Q8R4T5 | | Bait Uniprot Identifier | GRASP_RAT | | Bait Gene Name | Grasp | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 389-394 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | SPR; X-ray crystallography | | Interaction ID | 20636 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17396155 | | Comments | Tamalin self-assembles into autoinhibited conformations, through the interaction of its PDZ domain and C-terminal PDZ ligand motif |
Record No : 12 |
| Instance ID | 10637 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | LGATGL | | Bait Uniprot Accession | P19490 | | Bait Uniprot Identifier | GRIA1_RAT | | Bait Gene Name | Gria1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 902-907 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Mutation analysis; NMR; Co-IP; X-ray crystallography | | Interaction ID | 20637 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12070168, 16634638, 17069616 | | Comments | C-terminal PDZ domain-binding motif in rat AMPA-selective Glutamate receptor 1 (Gria1) that binds to the second PDZ domain of rat Dlg1/SAP-97 |
Record No : 13 |
| Instance ID | 10638 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | LEDSVF | | Bait Uniprot Accession | Q01344 | | Bait Uniprot Identifier | IL5RA_HUMAN | | Bait Gene Name | IL5RA | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 415-420 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | SPR; Co-IP; Y2H; Pull down; Mutation analysis; X-ray crystallography | | Interaction ID | 20638 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11498591, 12842047 | | Comments | Human Syntenin-1 (SDCBP), a protein containing PDZ domains, associates with the class 1 PDZ-binding motif in the cytoplasmic tail of human Interleukin-5 receptor subunit alpha (IL5RA) |
Record No : 14 |
| Instance ID | 10639 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | RRESAI | | Bait Uniprot Accession | P48050 | | Bait Uniprot Identifier | KCNJ4_HUMAN | | Bait Gene Name | KCNJ4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 440-445 | | Critical Residues | P4 | | Motif PTM(s) | Phosphorylation at Ser-P4 | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down; ITC; Mutation analysis; X-ray crystallography | | Interaction ID | 20639 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 19635485 | | Comments | C-terminal class 1 PDZ-binding motif in human Inward rectifier K(+) channel Kir2.3 protein (KCNJ4) that mediates binding to the human Tax1-binding protein 3 (TAX1BP3)/ Tax-interacting protein 1 (TIP1) |
Record No : 15 |
| Instance ID | 10640 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | WDETNL | | Bait Uniprot Accession | O55043 | | Bait Uniprot Identifier | ARHG7_RAT | | Bait Gene Name | Arhgef7 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 641-646 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography | | Interaction ID | 20640 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20117114 | | Comments | C-terminal class 1 PDZ-binding motif in rat Beta-Pix/p21-activated kinase interacting exchange factor/Arhgef7 that binds to the rat Shank1 PDZ domain through an extensive beta-sheet interaction |
Record No : 16 |
| Instance ID | 10641 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | EQVSAV | | Bait Uniprot Accession | Q8TEU7 | | Bait Uniprot Identifier | RPGF6_HUMAN | | Bait Gene Name | RAPGEF6 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1596-1601 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography; Competition binding; NMR | | Interaction ID | 20641 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20430886, 12095257 | | Comments | C-terminal class 1 PDZ-binding motif in human Rap guanine nucleotide exchange factor 6 (RAPGEF6) that binds to the PDZ domain of human Tyrosine-protein phosphatase non-receptor type 13 (PTPN13) |
Record No : 17 |
| Instance ID | 10642 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | LEDTEL | | Bait Uniprot Accession | Q495M9 | | Bait Uniprot Identifier | USH1G_HUMAN | | Bait Gene Name | USH1G | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 456-461 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; X-ray crystallography; ITC; Pull down(GST tag) | | Interaction ID | 20642 | | Interacting Domain | PDZ domain | | Disease Association(s) | Usher's Syndrome | | Inhibitor(s) | Unknown | | Reference(s) | 20142502, 16283141, 12588794 | | Comments | C-terminal class 1 PDZ-binding motif in human Usher syndrome type-1G protein (USH1G/SANS) that binds to the first PDZ domain of Harmonin (USH1C) |
Record No : 18 |
| Instance ID | 10643 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | KIATLV | | Bait Uniprot Accession | P89079 | | Bait Uniprot Identifier | E4OR1_ADE09 | | Bait Gene Name | E4 | | Bait Organism | Human adenovirus D serotype 9 (HAdV-9) (Human adenovirus 9) | | Sequence Position | 120-125 | | Critical Residues | P4; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down; Co-IP; Mutation analysis | | Interaction ID | 20643 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 11000240 | | Comments | PDZ domain-binding motif in the Ad9 E4-ORF1 oncoprotein that mediates binding to the PDZ7 and PDZ10 domains of rat Mupp1 (Mpdz) |
Record No : 19 |
| Instance ID | 10644 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | RRETQL | | Bait Uniprot Accession | P03126 | | Bait Uniprot Identifier | VE6_HPV16 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 16 | | Sequence Position | 153-158 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | NMR; SPR | | Interaction ID | 20644 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 21238461 | | Comments | C-terminal sequences in E6 oncoprotein of Human papillomavirus type 16 carrying the consensus PDZ-binding motif which binds to the second PDZ domain of MAGI-1 (MAGI-1 PDZ1) |
Record No : 20 |
| Instance ID | 10645 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | GGETRL | | Bait Uniprot Accession | P03524 | | Bait Uniprot Identifier | VGLG_RABVE | | Bait Gene Name | G | | Bait Organism | Rabies virus (strain ERA) (RABV) | | Sequence Position | 519-524 | | Critical Residues | P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | ITC; Y2H; Mutation analysis | | Interaction ID | 20645 | | Interacting Domain | PDZ domain | | Disease Association(s) | Rabies | | Inhibitor(s) | Unknown | | Reference(s) | 20086240 | | Comments | C-terminal class 1 PDZ-binding motif in the envelope glycoprotein (G) of Rabies virus (RABV) that binds to the PDZ domain of human Microtubule-associated serine/threonine-protein kinase 2 (MAST2) |
Record No : 21 |
| Instance ID | 10646 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | SEETQL | | Bait Uniprot Accession | Q7TFX0 | | Bait Uniprot Identifier | Q7TFX0_RHCM6 | | Bait Gene Name | Not Available | | Bait Organism | Rhesus cytomegalovirus (strain 68-1) (RhCMV) | | Sequence Position | 141-146 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Display technology | | Interaction ID | 20646 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18828675 | | Comments | C-terminal class 1 PDZ-binding motif in the Rh11 protein of Rhesus cytomegalovirus that binds to the human Scribble (SCRIB) PDZ domain |
Record No : 22 |
| Instance ID | 10647 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | TRETSL | | Bait Uniprot Accession | Q9DWF6 | | Bait Uniprot Identifier | Q9DWF6_RCMVM | | Bait Gene Name | R35 | | Bait Organism | Rat cytomegalovirus (strain Maastricht) | | Sequence Position | 516-521 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Display technology | | Interaction ID | 20647 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18828675 | | Comments | C-terminal class 1 PDZ-binding motif in the R35 protein of Rat cytomegalovirus that binds to the human Scribble (SCRIB) PDZ domain |
Record No : 23 |
| Instance ID | 10648 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | LLETDV | | Bait Uniprot Accession | Q9Q8F7 | | Bait Uniprot Identifier | Q9Q8F7_MYXVL | | Bait Gene Name | m147R | | Bait Organism | Myxoma virus (strain Lausanne) (MYXV) | | Sequence Position | 283-288 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Display technology | | Interaction ID | 20648 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18828675 | | Comments | C-terminal class 1 PDZ-binding motif in the M147R protein of Myxoma virus that binds to the human Scribble (SCRIB) PDZ domain |
Record No : 24 |
| Instance ID | 10649 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | LMETDV | | Bait Uniprot Accession | Q9Q8T6 | | Bait Uniprot Identifier | Q9Q8T6_RFVKA | | Bait Gene Name | s147R | | Bait Organism | Rabbit fibroma virus (strain Kasza) (RFV) (Shope fibroma virus (strain Kasza)) | | Sequence Position | 282-287 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Display technology | | Interaction ID | 20649 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18828675 | | Comments | C-terminal class 1 PDZ-binding motif in the Gp147R protein of Rabbit fibroma virus that binds to the human Scribble (SCRIB) PDZ domain |
Record No : 25 |
| Instance ID | 10650 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | DRETDV | | Bait Uniprot Accession | P26672 | | Bait Uniprot Identifier | A46_VACCW | | Bait Gene Name | A46R | | Bait Organism | Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) | | Sequence Position | 235-240 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Display technology | | Interaction ID | 20650 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18828675 | | Comments | C-terminal class 1 PDZ-binding motif in the A46 protein of Vaccinia virus that binds to the human Scribble (SCRIB) PDZ domain |
Record No : 26 |
| Instance ID | 10651 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | RRTTPV | | Bait Uniprot Accession | O88602 | | Bait Uniprot Identifier | CCG2_MOUSE | | Bait Gene Name | Cacng2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 318-323 | | Critical Residues | P4 | | Motif PTM(s) | Phosphorylation at Thr-P4 | | Secondary Structure | Disordered | | Experimental Method(s) | Protein kinase assay; Mutation analysis; Western blot | | Interaction ID | 20651 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11805122 | | Comments | C-terminal class 1 PDZ-binding motif in mouse Neuronal voltage-gated calcium channel gamma-2 subunit/ Stargazin (Cacng2) that binds to the PDZ domain of mouse Dlg4/PSD-95/SAP-90 |
Record No : 27 |
| Instance ID | 10652 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | QSSSSL | | Bait Uniprot Accession | P31424 | | Bait Uniprot Identifier | GRM5_RAT | | Bait Gene Name | Grm5 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1198-1203 | | Critical Residues | P2; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography; SPR; Mutation analysis | | Interaction ID | 20652 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17396155 | | Comments | C-terminal class 1 PDZ-binding motif in rat Metabotropic glutamate receptor 5 (mGluR5/Grm5) that binds to the PDZ domain of rat Tamalin/Grasp |
Record No : 28 |
| Instance ID | 10653 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | YLVTSV | | Bait Uniprot Accession | Q61315 | | Bait Uniprot Identifier | APC_MOUSE | | Bait Gene Name | Apc | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 2840-2845 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | NMR | | Interaction ID | 20653 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17161370 | | Comments | C-terminal class 1 PDZ-binding motif in mouse Adenomatous polyposis coli protein (Apc) that binds to the PDZ domain of mouse Protein tyrosine phosphatase PTP-BL (Ptpn13) |
Record No : 29 |
| Instance ID | 10654 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | PFLTWL | | Bait Uniprot Accession | Q9EPK5 | | Bait Uniprot Identifier | WWTR1_MOUSE | | Bait Gene Name | Wwtr1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 390-395 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Co-IP; Pull down; Mutation analysis | | Interaction ID | 20654 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11118213 | | Comments | C-terminal class 1 PDZ-binding motif in mouse Transcriptional coactivator with PDZ-binding motif (Taz) that binds to the PDZ domain of mouse Na(+)/H(+) exchange regulatory cofactor Nherf2/ NHE3 kinase A regulatory protein E3KARP (Slc9a3r2) |
Record No : 30 |
| Instance ID | 10655 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | SFLTWL | | Bait Uniprot Accession | P46937 | | Bait Uniprot Identifier | YAP1_HUMAN | | Bait Gene Name | YAP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 483-488 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | ITC; Pull down; Co-IP; Colocalization; Mutation analysis | | Interaction ID | 20655 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20868367 | | Comments | Class 1 PDZ-binding motif (483-488) in human YAP1 (Yes kinase-associated protein 1) that binds to the first PDZ domain of Tight junction protein ZO-2 (TJP2) |
Record No : 31 |
| Instance ID | 10656 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | VQDTRL | | Bait Uniprot Accession | P13569 | | Bait Uniprot Identifier | CFTR_HUMAN | | Bait Gene Name | CFTR | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1475-1480 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography; Far Western blotting; SPR; Pull down; Mutation analysis; Western blot | | Interaction ID | 20656 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11304524, 9677412 | | Comments | C-terminal PDZ domain-binding motif in human Cystic fibrosis transmembrane conductance regulator (CFTR) that mediates binding to the first PDZ domain of the Na+/H+ exchanger regulatory factor (NHERF/EBP50) |
Record No : 32 |
| Instance ID | 10657 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | SFLTWL | | Bait Uniprot Accession | P46937 | | Bait Uniprot Identifier | YAP1_HUMAN | | Bait Gene Name | YAP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 499-504 | | Critical Residues | P3; P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation disrupting interaction; Peptide binding to perpetrator; Pull down; Co-IP; Colocalization; Competition binding; Mutation analysis | | Interaction ID | 20657 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10562288 | | Comments | C-terminal class 1 PDZ-binding motif (499-504) in human Cystic fibrosis transmembrane conductance regulator (CFTR) that mediates binding to the PDZ domain of Na(+)/H(+) exchange regulatory cofactor NHERF1/EBP50 (SLC9A3R1) |
Record No : 33 |
| Instance ID | 10658 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | SFLTWL | | Bait Uniprot Accession | P46937 | | Bait Uniprot Identifier | YAP1_HUMAN | | Bait Gene Name | YAP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 449-454 | | Critical Residues | P3; P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down; Co-IP; Competition binding; Mutation analysis | | Interaction ID | 20658 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10562288 | | Comments | Class 1 PDZ-binding motif (449-454) in human Cystic fibrosis transmembrane conductance regulator (CFTR) that mediates binding to the PDZ domain of Na(+)/H(+) exchange regulatory cofactor NHERF1/EBP50 (SLC9A3R1) |
Record No : 34 |
| Instance ID | 10659 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | RKRTYL | | Bait Uniprot Accession | P36762 | | Bait Uniprot Identifier | VL2_HPV49 | | Bait Gene Name | L2 | | Bait Organism | Human papillomavirus type 49 | | Sequence Position | 516-521 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Display technology | | Interaction ID | 20659 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18828675 | | Comments | C-terminal class 1 PDZ-binding motif in the Minor capsid protein L2 of Human papillomavirus that binds to the human Scribble (SCRIB) PDZ domain |
Record No : 35 |
| Instance ID | 10660 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | RRETQV | | Bait Uniprot Accession | P06463 | | Bait Uniprot Identifier | VE6_HPV18 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 18 | | Sequence Position | 153-158 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography; ITC; NMR | | Interaction ID | 20660 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 17267502, 17713926 | | Comments | C terminal binding motif of E6 oncoprotein of Human papillomavirus type 18 that binds to all three PDZ domains of DLG and causes a dramatic reduction in the levels of DLG expression by targeting it for proteasome mediated degradation |
Record No : 36 |
| Instance ID | 10661 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | VQQTRV | | Bait Uniprot Accession | Q9QUH6 | | Bait Uniprot Identifier | SYGP1_RAT | | Bait Gene Name | Syngap1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1303-1308 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down; Co-IP; Competition binding; Y2H | | Interaction ID | 20661 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9581761 | | Comments | C-terminal class 1 PDZ-binding motif in rat Ras-GTPase activating protein, Syngap1 that binds to the PDZ domain of rat Dlg4 or Psd95 |
Record No : 37 |
| Instance ID | 10662 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | VQQTRV | | Bait Uniprot Accession | Q9QUH6 | | Bait Uniprot Identifier | SYGP1_RAT | | Bait Gene Name | Syngap1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1303-1308 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down; Co-IP; Competition binding; Y2H | | Interaction ID | 20662 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9581761 | | Comments | C-terminal class 1 PDZ-binding motif in rat Ras-GTPase activating protein, Syngap1 that binds to the PDZ domain of rat Dlg3 or SAP-102 |
Record No : 38 |
| Instance ID | 10663 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | FRETEV | | Bait Uniprot Accession | P03409 | | Bait Uniprot Identifier | TAX_HTL1A | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) | | Sequence Position | 348-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Y2H; Western blot; Co-IP; Mutation analysis | | Interaction ID | 20663 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482110 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) that binds to the PDZ domain of rat Dlg4 or Psd95 |
Record No : 39 |
| Instance ID | 10664 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | SLESCF | | Bait Uniprot Accession | P97288 | | Bait Uniprot Identifier | 5HT4R_MOUSE | | Bait Gene Name | Htr4 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 382-387 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Affinity chromatography technology; Co-IP; Confocal microscopy; Mutation analysis | | Interaction ID | 20664 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15466885 | | Comments | C-terminal class 1 PDZ-binding motif in mouse 5-hydroxytryptamine receptor 4 (Htr4) that binds to the PDZ domain of mouse Sorting nexin-27 (Snx27) |
Record No : 40 |
| Instance ID | 10665 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | LWETSI | | Bait Uniprot Accession | Q9P0K1 | | Bait Uniprot Identifier | ADA22_HUMAN | | Bait Gene Name | ADAM22 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 901-906 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Co-IP; Co-IP; Mutation analysis | | Interaction ID | 20665 | | Interacting Domain | PDZ domain | | Disease Association(s) | Epilepsy | | Inhibitor(s) | Unknown | | Reference(s) | 16990550 | | Comments | C-terminal PDZ domain-binding motif in human Metalloproteinase-disintegrin ADAM22 that mediates binding to the PDZ domain of human Leucine-rich glioma-inactivated protein 1/ Epitempin-1 (LGI1) |
Record No : 41 |
| Instance ID | 10666 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | SLETSL | | Bait Uniprot Accession | Q01814 | | Bait Uniprot Identifier | AT2B2_HUMAN | | Bait Gene Name | ATP2B2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1238-1243 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Y2H; Pull down; Co-IP; Colocalization | | Interaction ID | 20666 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11786550 | | Comments | C-terminal PDZ domain-binding motif in human Plasma membrane calcium-transporting ATPase 2 (ATP2B2) that mediates binding to the PDZ domain of human Sodium-hydrogen exchanger regulatory cofactor NHERF-2 (SLC9A3R2) |
Record No : 42 |
| Instance ID | 10667 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | TLVSTV | | Bait Uniprot Accession | Q9UQB8 | | Bait Uniprot Identifier | BAIP2_HUMAN | | Bait Gene Name | BAIAP2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 516-521 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Affinity chromatography technology; Peptide binding to perpetrator; Co-IP; Colocalization | | Interaction ID | 20667 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15255944 | | Comments | Class 1 PDZ domain-binding motif in Isoform BAIAP2-alpha of human Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2)/ Insulin receptor substrate p53 (IRSp53) that mediates binding to the PDZ domain of human SHANK1 |
Record No : 43 |
| Instance ID | 10668 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | TLVSTV | | Bait Uniprot Accession | Q9UQB8 | | Bait Uniprot Identifier | BAIP2_HUMAN | | Bait Gene Name | BAIAP2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 516-521 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Affinity chromatography technology; Peptide binding to perpetrator; Co-IP; Colocalization | | Interaction ID | 20668 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15255944 | | Comments | Class 1 PDZ domain-binding motif in Isoform BAIAP2-alpha of human Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2)/ Insulin receptor substrate p53 (IRSp53) that mediates binding to the PDZ domain of human DLG4/PSD-95/SAP-90 |
Record No : 44 |
| Instance ID | 10669 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | SVSTVV | | Bait Uniprot Accession | Q05586 | | Bait Uniprot Identifier | NMDZ1_HUMAN | | Bait Gene Name | GRIN1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 917-922 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Mutation analysis | | Interaction ID | 20669 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11163274 | | Comments | Class 1 PDZ domain-binding motif in Isoform 4 of human Glutamate [NMDA] receptor subunit NR1 (GRIN1/NMDAR1) that mediates binding to the PDZ domain of human DLG4/PSD-95/SAP-90 |
Record No : 45 |
| Instance ID | 10670 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | ASGSSV | | Bait Uniprot Accession | O55207 | | Bait Uniprot Identifier | SYNJ2_RAT | | Bait Gene Name | Synj2 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1288-1293 | | Critical Residues | P4; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Peptide binding to perpetrator | | Interaction ID | 20670 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10357812 | | Comments | Class 1 PDZ domain-binding motif in Isoform 7.5kb of mouse Synaptojanin-2 (Synj2) that binds to the PDZ domain of mouse Synaptojanin-2-binding protein (Synj2bp)/ Mitochondrial outer membrane protein 25 (Omp25) |
Record No : 46 |
| Instance ID | 10671 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | RKETVA | | Bait Uniprot Accession | P22756 | | Bait Uniprot Identifier | GRIK1_RAT | | Bait Gene Name | Grik1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 900-905 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H; Pull down(GST tag) | | Interaction ID | 20671 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12597860 | | Comments | Class 1 PDZ domain-binding motif in Isoform Glur5-2 of rat Glutamate receptor 5 (Grik1/Glur5) that binds to the PDZ domain of rat Pick1 |
Record No : 47 |
| Instance ID | 10672 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | LTASEV | | Bait Uniprot Accession | Q66T02 | | Bait Uniprot Identifier | PKHG5_MOUSE | | Bait Gene Name | Plekhg5 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 1068-1073 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP | | Interaction ID | 20672 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 16467373 | | Comments | C-terminal class 1 PDZ-binding motif in mouse Synectin-binding RhoA exchange factor (Syx/Plekhg5) that binds to the PDZ domain of mouse PDZ adaptor protein synectin (Gipc1) leading to targeting of Syx to the plasma membrane |
Record No : 48 |
| Instance ID | 10673 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | LNSTTL | | Bait Uniprot Accession | P51790 | | Bait Uniprot Identifier | CLCN3_HUMAN | | Bait Gene Name | CLCN3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 861-866 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Pull down | | Interaction ID | 20673 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11967229 | | Comments | C-terminal class 1 PDZ-binding motif in ClC-3B, a splicing variant of human Chloride transporter ClC-3 (CLCN3) that mediates binding to the PDZ domain of human EBP50/NHERF1/SLC9A3R1 |
Record No : 49 |
| Instance ID | 10674 | | Regular Expression | xxx[VLIFY]x[ACVILF]$ | | Motif Instance | EQPVYI | | Bait Uniprot Accession | Q02410 | | Bait Uniprot Identifier | APBA1_HUMAN | | Bait Gene Name | APBA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 832-837 | | Critical Residues | P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Y2H; NMR; Mutation analysis | | Interaction ID | 20674 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16007100 | | Comments | The highly conserved C-terminal tail of human Adapter protein X11alpha folds back and inserts into the target-binding groove of its first PDZ domain forming an autoinhibited conformation |
Record No : 50 |
| Instance ID | 10675 | | Regular Expression | xxx[VLIFY]x[ACVILF]$ | | Motif Instance | QEELII | | Bait Uniprot Accession | P55284 | | Bait Uniprot Identifier | CADH5_MOUSE | | Bait Gene Name | Cdh5 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 779-784 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Fluorescence polarization spectroscopy; NMR | | Interaction ID | 20675 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20047332 | | Comments | The C-terminal class 2 PDZ-binding motif of mouse Vascular endothelial cadherin (VE-Cad)/ Cadherin-5 (Cdh5) that binds to the third PDZ domain of mouse Pard3 (par3-PDZ3) |
Record No : 51 |
| Instance ID | 10676 | | Regular Expression | xxx[VLIFY]x[ACVILF]$ | | Motif Instance | EEGIWA | | Bait Uniprot Accession | Q811U3 | | Bait Uniprot Identifier | RB6I2_RAT | | Bait Gene Name | Erc1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 943-948 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | ITC; NMR | | Interaction ID | 20676 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16095618 | | Comments | The C-terminal class 2 PDZ-binding motif of rat Elks (Erc1) that binds to the PDZ domain of rat Rim1 (Rims1) |
Record No : 52 |
| Instance ID | 10677 | | Regular Expression | xxx[VLIFY]x[ACVILF]$ | | Motif Instance | IESVKI | | Bait Uniprot Accession | P19491 | | Bait Uniprot Identifier | GRIA2_RAT | | Bait Gene Name | Gria2 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 878-883 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | NMR | | Interaction ID | 20677 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17914463 | | Comments | The C-terminal class 2 PDZ-binding motif of rat Glutamate receptor 2 (Gria2) that binds to the PDZ domain of rat Pick1 |
Record No : 53 |
| Instance ID | 10678 | | Regular Expression | xxx[VLIFY]x[ACVILF]$ | | Motif Instance | VRTYSC | | Bait Uniprot Accession | Q13136 | | Bait Uniprot Identifier | LIPA1_HUMAN | | Bait Gene Name | PPFIA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1197-1202 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography | | Interaction ID | 20678 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12493751 | | Comments | The C-terminal class 2 PDZ-binding motif of human Liprin-alpha-1 (PPFIA1) that binds to the sixth PDZ domain of rat Grip1 |
Record No : 54 |
| Instance ID | 10679 | | Regular Expression | xxx[VLIFY]x[ACVILF]$ | | Motif Instance | RKEYFI | | Bait Uniprot Accession | P04921 | | Bait Uniprot Identifier | GLPC_HUMAN | | Bait Gene Name | GYPC | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 123-128 | | Critical Residues | P4; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; NMR | | Interaction ID | 20679 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9305870, 17572384 | | Comments | The PDZ domain of human 55 kDa erythrocyte membrane protein (MPP1) mediates its binding to the cytoplasmic carboxyl terminus of Glycophorin-C |
Record No : 55 |
| Instance ID | 10680 | | Regular Expression | xxx[VLIFY]x[ACVILF]$ | | Motif Instance | TNEFYA | | Bait Uniprot Accession | P31431 | | Bait Uniprot Identifier | SDC4_HUMAN | | Bait Gene Name | SDC4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 193-198 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | ITC; X-ray crystallography | | Interaction ID | 20680 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12679023, 16533050, 12842047 | | Comments | The C-terminal class 2 PDZ-binding motif of human Syndecan-4 (SDC4) that binds to the PDZ domain of human Syntenin-1 (SDCBP) |
Record No : 56 |
| Instance ID | 10681 | | Regular Expression | xxx[VLIFY]x[ACVILF]$ | | Motif Instance | GLDVPV | | Bait Uniprot Accession | P04626 | | Bait Uniprot Identifier | ERBB2_HUMAN | | Bait Gene Name | ERBB2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1250-1255 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | ITC; X-ray crystallography | | Interaction ID | 20681 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12444095 | | Comments | The C-terminal class 2 PDZ-binding motif of the human receptor tyrosine kinase ErbB2 (ERBB2) that binds to the PDZ domain of human ERBIN/LAP2 (ERBB2IP) |
Record No : 57 |
| Instance ID | 10682 | | Regular Expression | xxx[VLIFY]x[ACVILF]$ | | Motif Instance | DKEYYV | | Bait Uniprot Accession | Q07310 | | Bait Uniprot Identifier | NRX3A_RAT | | Bait Gene Name | Nrxn3 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1573-1578 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Y2H | | Interaction ID | 20682 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9707552 | | Comments | The C-terminal class 2 PDZ-binding motif of rat Neurexin III-alpha (Nrxn3) that binds to the PDZ domain of rat Af6 (Mllt4) |
Record No : 58 |
| Instance ID | 10683 | | Regular Expression | xxx[VLIFY]x[ACVILF]$ | | Motif Instance | QEEFYA | | Bait Uniprot Accession | P18827 | | Bait Uniprot Identifier | SDC1_HUMAN | | Bait Gene Name | SDC1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 305-310 | | Critical Residues | P5 | | Motif PTM(s) | Phosphorylation at Tyr-P5 | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down; Mutation analysis | | Interaction ID | 20683 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 19228696 | | Comments | The C-terminal class 2 PDZ-binding motif of human Syndecan-1 (SDC1) that binds to the PDZ domain of human Syntenin-1 (SDCBP) on dephosphorylation of Tyr-309 |
Record No : 59 |
| Instance ID | 10684 | | Regular Expression | xxx[VLIFY]x[ACVILF]$ | | Motif Instance | FHQFYI | | Bait Uniprot Accession | P49768 | | Bait Uniprot Identifier | PSN1_HUMAN | | Bait Gene Name | PSEN1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 462-467 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Y2H; Colocalization; Co-IP; Pull down | | Interaction ID | 20684 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10551805, 11083918 | | Comments | The C-terminal class 2 PDZ-binding motif of human Presenilin-1 (PSEN1) that binds to the PDZ domain of human Adapter protein X11alpha (APBA1) |
Record No : 60 |
| Instance ID | 10685 | | Regular Expression | xxx[VLIFY]x[ACVILF]$ | | Motif Instance | DREYYV | | Bait Uniprot Accession | Q9Y4C0 | | Bait Uniprot Identifier | NRX3A_HUMAN | | Bait Gene Name | NRXN3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1638-1643 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Y2H | | Interaction ID | 20685 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9707552 | | Comments | The C-terminal class 2 PDZ-binding motif of human Neurexin III-alpha (NRXN3) that binds to the PDZ domain of rat Af6 (Mllt4) |
Record No : 61 |
| Instance ID | 10686 | | Regular Expression | xxx[VLIFY]x[ACVILF]$ | | Motif Instance | NRPVPV | | Bait Uniprot Accession | P97288 | | Bait Uniprot Identifier | 5HT4R_MOUSE | | Bait Gene Name | Htr4 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 366-371 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Affinity chromatography technology; Confocal microscopy; Mutation analysis | | Interaction ID | 20686 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15466885 | | Comments | The Class 2 PDZ-binding motif of Isoform 5-HT4(E) of mouse 5-hydroxytryptamine receptor 4 (Htr4) that binds to the PDZ domain of mouse Inadl/Cipp |
Record No : 62 |
| Instance ID | 10687 | | Regular Expression | xxx[DE]x[ACVILF]$ | | Motif Instance | VKVDSV | | Bait Uniprot Accession | P48039 | | Bait Uniprot Identifier | MTR1A_HUMAN | | Bait Gene Name | MTNR1A | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 345-350 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | NMR | | Interaction ID | 20687 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10331866 | | Comments | The Class 2 PDZ-binding motif of human Melatonin receptor type 1A (MTNR1A) that binds to rat nNOS PDZ domain |
Record No : 63 |
| Instance ID | 11226 | | Regular Expression | [ST]x[VL]D | | Motif Instance | SSVD | | Bait Uniprot Accession | Q01484 | | Bait Uniprot Identifier | ANK2_HUMAN | | Bait Gene Name | ANK2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 88-91 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21226 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22876914 | | Comments | Novel internal motif identified in human Ankyrin-2 that is recognized by human Glutaminase-interacting protein (GIP), also known as Tax-interacting protein 1 (TIP1) or Tax1-binding protein 3 (TAX1BP3), composed almost exclusively of a single PDZ domain |
Record No : 64 |
| Instance ID | 11227 | | Regular Expression | [ST]x[VL]D | | Motif Instance | SSVD | | Bait Uniprot Accession | Q15648 | | Bait Uniprot Identifier | MED1_HUMAN | | Bait Gene Name | MED1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1370-1373 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21227 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22876914 | | Comments | Novel internal motif identified in human Mediator complex subunit 1 (MED1) that is recognized by human Glutaminase-interacting protein (GIP), also known as Tax-interacting protein 1 (TIP1) or Tax1-binding protein 3 (TAX1BP3), composed almost exclusively of a single PDZ domain |
Record No : 65 |
| Instance ID | 11228 | | Regular Expression | [ST]x[VL]D | | Motif Instance | SSVD | | Bait Uniprot Accession | Q9NQC7 | | Bait Uniprot Identifier | CYLD_HUMAN | | Bait Gene Name | CYLD | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 361-364 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21228 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22876914 | | Comments | Novel internal motif identified in human Ubiquitin carboxyl-terminal hydrolase CYLD that is recognized by human Glutaminase-interacting protein (GIP), also known as Tax-interacting protein 1 (TIP1) or Tax1-binding protein 3 (TAX1BP3), composed almost exclusively of a single PDZ domain |
Record No : 66 |
| Instance ID | 11229 | | Regular Expression | [ST]x[VL]D | | Motif Instance | SSVD | | Bait Uniprot Accession | Q8IUG5 | | Bait Uniprot Identifier | MY18B_HUMAN | | Bait Gene Name | MYO18B | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 2389-2392 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21229 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22876914 | | Comments | Novel internal motif identified in human Unconventional myosin-XVIIIb (MYO18B) that is recognized by human Glutaminase-interacting protein (GIP), also known as Tax-interacting protein 1 (TIP1) or Tax1-binding protein 3 (TAX1BP3), composed almost exclusively of a single PDZ domain |
Record No : 67 |
| Instance ID | 11230 | | Regular Expression | [ST]x[VL]D | | Motif Instance | SSVD | | Bait Uniprot Accession | O95352 | | Bait Uniprot Identifier | ATG7_HUMAN | | Bait Gene Name | ATG7 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 331-334 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21230 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22876914 | | Comments | Novel internal motif identified in human Ubiquitin-like modifier-activating enzyme ATG7 that is recognized by human Glutaminase-interacting protein (GIP), also known as Tax-interacting protein 1 (TIP1) or Tax1-binding protein 3 (TAX1BP3), composed almost exclusively of a single PDZ domain |
Record No : 68 |
| Instance ID | 11231 | | Regular Expression | [ST]x[VL]D | | Motif Instance | SSVD | | Bait Uniprot Accession | Q9BRR9 | | Bait Uniprot Identifier | RHG09_HUMAN | | Bait Gene Name | ARHGAP9 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 381-384 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21231 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22876914 | | Comments | Novel internal motif identified in human Rho GTPase-activating protein 9 (ARHGAP9) that is recognized by human Glutaminase-interacting protein (GIP), also known as Tax-interacting protein 1 (TIP1) or Tax1-binding protein 3 (TAX1BP3), composed almost exclusively of a single PDZ domain |
Record No : 69 |
| Instance ID | 11232 | | Regular Expression | [ST]x[VL]D | | Motif Instance | SSLD | | Bait Uniprot Accession | Q13426 | | Bait Uniprot Identifier | XRCC4_HUMAN | | Bait Gene Name | XRCC4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 259-262 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21232 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22876914 | | Comments | Novel internal motif identified in human DNA repair protein XRCC4 that is recognized by human Glutaminase-interacting protein (GIP), also known as Tax-interacting protein 1 (TIP1) or Tax1-binding protein 3 (TAX1BP3), composed almost exclusively of a single PDZ domain |
Record No : 70 |
| Instance ID | 11233 | | Regular Expression | [ST]x[VL]D | | Motif Instance | TSLD | | Bait Uniprot Accession | Q96T23 | | Bait Uniprot Identifier | RSF1_HUMAN | | Bait Gene Name | RSF1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 539-542 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21233 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22876914 | | Comments | Novel internal motif identified in human Remodeling and spacing factor 1 (RSF1) that is recognized by human Glutaminase-interacting protein (GIP), also known as Tax-interacting protein 1 (TIP1) or Tax1-binding protein 3 (TAX1BP3), composed almost exclusively of a single PDZ domain |
Record No : 71 |
| Instance ID | 11234 | | Regular Expression | [ST]x[VL]D | | Motif Instance | TNLD | | Bait Uniprot Accession | O43719 | | Bait Uniprot Identifier | HTSF1_HUMAN | | Bait Gene Name | HTATSF1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 4-7 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21234 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22876914 | | Comments | Novel internal motif identified in human HIV Tat-specific factor 1 (HTATSF1) that is recognized by human Glutaminase-interacting protein (GIP), also known as Tax-interacting protein 1 (TIP1) or Tax1-binding protein 3 (TAX1BP3), composed almost exclusively of a single PDZ domain |
Record No : 72 |
| Instance ID | 11235 | | Regular Expression | [ST]x[VL]D | | Motif Instance | SGLD | | Bait Uniprot Accession | Q13610 | | Bait Uniprot Identifier | PWP1_HUMAN | | Bait Gene Name | PWP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 389-392 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21235 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 22876914 | | Comments | Novel internal motif identified in human PWP1 that is recognized by human Glutaminase-interacting protein (GIP), also known as Tax-interacting protein 1 (TIP1) or Tax1-binding protein 3 (TAX1BP3), composed almost exclusively of a single PDZ domain |
Record No : 73 |
| Instance ID | 11483 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TSV | | Bait Uniprot Accession | P25054 | | Bait Uniprot Identifier | APC_HUMAN | | Bait Gene Name | APC | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 2841-2843 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | SPR; Pull down(GST tag) | | Interaction ID | 21483 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11029657 | | Comments | PDZ domain binding C-terminal S/TXV motif in APC that binds to the second PDZ domain (PDZ2) of PSD-95(DLG4) protein |
Record No : 74 |
| Instance ID | 11484 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TKV | | Bait Uniprot Accession | P60484 | | Bait Uniprot Identifier | PTEN_HUMAN | | Bait Gene Name | PTEN | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 401-403 | | Critical Residues | P1; P2; P3 | | Motif PTM(s) | Phosphorylation at Thr-P1 | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag); Y2H | | Interaction ID | 21484 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10646847, 15951562 | | Comments | C-terminal tail of PTEN that interacts with the second PDZ domain of hDLG |
Record No : 75 |
| Instance ID | 11485 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TKV | | Bait Uniprot Accession | P60484 | | Bait Uniprot Identifier | PTEN_HUMAN | | Bait Gene Name | PTEN | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 401-403 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag); Y2H | | Interaction ID | 21485 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15951562 | | Comments | C-terminal tail of PTEN that interacts with the PDZ domain of MAST1 |
Record No : 76 |
| Instance ID | 11486 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TKV | | Bait Uniprot Accession | P60484 | | Bait Uniprot Identifier | PTEN_HUMAN | | Bait Gene Name | PTEN | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 401-403 | | Critical Residues | P2; P3 | | Motif PTM(s) | Phosphorylation at Thr-P1 | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag); Y2H | | Interaction ID | 21486 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10646847, 15951562 | | Comments | C-terminal tail of PTEN that interacts with the single PDZ domain from hMAST205 |
Record No : 77 |
| Instance ID | 11487 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TKV | | Bait Uniprot Accession | P60484 | | Bait Uniprot Identifier | PTEN_HUMAN | | Bait Gene Name | PTEN | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 401-403 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag); Y2H | | Interaction ID | 21487 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15951562 | | Comments | C-terminal tail of PTEN that interacts with the PDZ domain of MAST3 |
Record No : 78 |
| Instance ID | 11488 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TKV | | Bait Uniprot Accession | P60484 | | Bait Uniprot Identifier | PTEN_HUMAN | | Bait Gene Name | PTEN | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 401-403 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis | | Interaction ID | 21488 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15629897, 15951562 | | Comments | C-terminal tail of PTEN that interacts with the second PDZ domain of MAGI1 |
Record No : 79 |
| Instance ID | 11489 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TKV | | Bait Uniprot Accession | P60484 | | Bait Uniprot Identifier | PTEN_HUMAN | | Bait Gene Name | PTEN | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 401-403 | | Critical Residues | P2; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag); Y2H | | Interaction ID | 21489 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 10760291, 15951562 | | Comments | C-terminal tail of PTEN that interacts with PDZ-2/MAGI-2 |
Record No : 80 |
| Instance ID | 11490 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TKV | | Bait Uniprot Accession | P60484 | | Bait Uniprot Identifier | PTEN_HUMAN | | Bait Gene Name | PTEN | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 401-403 | | Critical Residues | P2; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag); Y2H | | Interaction ID | 21490 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 10748157, 15951562 | | Comments | C-terminal tail of PTEN that interacts with the PDZ domain 2 of MAGI3 to position PTEN phosphatase to specific subcellular locations that are involved with the regulation of cell proliferation and survival |
Record No : 81 |
| Instance ID | 11491 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TDL | | Bait Uniprot Accession | Q02248 | | Bait Uniprot Identifier | CTNB1_MOUSE | | Bait Gene Name | Ctnnb1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 779-781 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Y2H; Competition binding assay | | Interaction ID | 21491 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10772923, 15629897 | | Comments | The extreme C-terminus of Beta-catenin that contains the consensus sequence for binding the fifth PDZ domain of MAGI-1 |
Record No : 82 |
| Instance ID | 11492 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | SDL | | Bait Uniprot Accession | O43707 | | Bait Uniprot Identifier | ACTN4_HUMAN | | Bait Gene Name | ACTN4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 909-911 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21492 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12042308 | | Comments | Consensus PDZ-binding motif at the extreme C-terminus of Alpha-actinin-4 which interacts with the fifth PDZ domain of MAGI-1 |
Record No : 83 |
| Instance ID | 11493 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TLV | | Bait Uniprot Accession | Q9Z206 | | Bait Uniprot Identifier | ARHG8_MOUSE | | Bait Gene Name | Net1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 593-595 | | Critical Residues | P1; P2; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Y2H; Co-IP; Pull down(GST tag) | | Interaction ID | 21493 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11350080 | | Comments | Consensus tripeptide for PDZ domain binding at the extreme carboxy-terminus of mNET1 that binds to the first PDZ domain of MAGI-1 |
Record No : 84 |
| Instance ID | 11494 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TLV | | Bait Uniprot Accession | Q7TSN7 | | Bait Uniprot Identifier | IGSF5_MOUSE | | Bait Gene Name | Igsf5 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 368-370 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Mutational analysis; Co-IP; Pull down(GST tag) | | Interaction ID | 21494 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12773569 | | Comments | PDZ-binding motif in JAM4 (Igsf5) which binds to PDZ1 and PDZ4 of MAGI-1 |
Record No : 85 |
| Instance ID | 11495 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TLV | | Bait Uniprot Accession | O94868 | | Bait Uniprot Identifier | FCSD2_HUMAN | | Bait Gene Name | FCHSD2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 738-740 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Mutational analysis; Co-IP; Pull down(GST tag) | | Interaction ID | 21495 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14627983 | | Comments | The PDZ-binding motif at the C-terminus of Carom (FCHSD2) which binds to the fifth PDZ domain (PDZ4) of MAGI-1 |
Record No : 86 |
| Instance ID | 11496 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | SDV | | Bait Uniprot Accession | A2ARV4 | | Bait Uniprot Identifier | LRP2_MOUSE | | Bait Gene Name | Lrp2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 4658-4660 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis | | Interaction ID | 21496 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11274227 | | Comments | Class I PDZ binding motif at the C-terminus of Megalin (Lrp2) that mediates its interaction with the fifth PDZ domain of Magi1 |
Record No : 87 |
| Instance ID | 11497 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | SDV | | Bait Uniprot Accession | A2ARV4 | | Bait Uniprot Identifier | LRP2_MOUSE | | Bait Gene Name | Lrp2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 4658-4660 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis | | Interaction ID | 21497 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11274227 | | Comments | Class I PDZ binding motif at the C-terminus of Megalin (Lrp2) that mediates its interaction with the fifth PDZ domain in Magi2 |
Record No : 88 |
| Instance ID | 11498 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQL | | Bait Uniprot Accession | P03126 | | Bait Uniprot Identifier | VE6_HPV16 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 16 | | Sequence Position | 156-158 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | SPR; Mutational analysis; Pull down(GST tag); In vitro-degradation assay | | Interaction ID | 21498 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20842623, 11077444 | | Comments | C-terminal sequences in E6 oncoprotein of Human papillomavirus type 16 carrying the consensus PDZ-binding motif which binds to the PDZ1 domain of MAGI-1 (MAGuK inverted protein 1) |
Record No : 89 |
| Instance ID | 11499 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQV | | Bait Uniprot Accession | P06463 | | Bait Uniprot Identifier | VE6_HPV18 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 18 | | Sequence Position | 156-158 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography; SPR; Mutational analysis; Pull down(GST tag); In vitro degradation assay | | Interaction ID | 21499 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20842623, 17267502, 11077444 | | Comments | C-terminal sequences in E6 oncoprotein of Human papillomavirus type 18 carrying the consensus PDZ-binding motif which binds to the PDZ1 domain of MAGI-1 (MAGuK inverted protein 1) |
Record No : 90 |
| Instance ID | 11500 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQV | | Bait Uniprot Accession | P17386 | | Bait Uniprot Identifier | VE6_HPV31 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 31 | | Sequence Position | 147-149 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | SPR; Mutational analysis | | Interaction ID | 21500 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20842623 | | Comments | C-terminal sequences in E6 oncoprotein of Human papillomavirus type 31 carrying the consensus PDZ-binding motif which binds to the PDZ1 domain of MAGI-1 (MAGuK inverted protein 1) |
Record No : 91 |
| Instance ID | 11501 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TAL | | Bait Uniprot Accession | P06427 | | Bait Uniprot Identifier | VE6_HPV33 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 33 | | Sequence Position | 147-149 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | SPR; Mutational analysis | | Interaction ID | 21501 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20842623 | | Comments | C-terminal sequences in E6 oncoprotein of Human papillomavirus type 33 carrying the consensus PDZ-binding motif which binds to the PDZ1 domain of MAGI-1 (MAGuK inverted protein 1) |
Record No : 92 |
| Instance ID | 11502 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQV | | Bait Uniprot Accession | P21735 | | Bait Uniprot Identifier | VE6_HPV45 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 45 | | Sequence Position | 156-158 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | SPR; Mutational analysis | | Interaction ID | 21502 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20842623 | | Comments | C-terminal sequences in E6 oncoprotein of Human papillomavirus type 45 carrying the consensus PDZ-binding motif which binds to the PDZ1 domain of MAGI-1 (MAGuK inverted protein 1) |
Record No : 93 |
| Instance ID | 11503 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQV | | Bait Uniprot Accession | P36814 | | Bait Uniprot Identifier | VE6_HPV52 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 52 | | Sequence Position | 146-148 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | SPR; Mutational analysis | | Interaction ID | 21503 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20842623 | | Comments | C-terminal sequences in E6 oncoprotein of Human papillomavirus type 52 carrying the consensus PDZ-binding motif which binds to the PDZ1 domain of MAGI-1 (MAGuK inverted protein 1) |
Record No : 94 |
| Instance ID | 11504 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQV | | Bait Uniprot Accession | P26555 | | Bait Uniprot Identifier | VE6_HPV58 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 58 | | Sequence Position | 147-149 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | SPR; Mutational analysis | | Interaction ID | 21504 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20842623 | | Comments | C-terminal sequences in E6 oncoprotein of Human papillomavirus type 58 carrying the consensus PDZ-binding motif which binds to the PDZ1 domain of MAGI-1 (MAGuK inverted protein 1) |
Record No : 95 |
| Instance ID | 11505 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TLV | | Bait Uniprot Accession | P89079 | | Bait Uniprot Identifier | E4OR1_ADE09 | | Bait Gene Name | E4 | | Bait Organism | Human adenovirus D serotype 9 (HAdV-9) (Human adenovirus 9) | | Sequence Position | 123-125 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | SPR; Mutational analysis | | Interaction ID | 21505 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20842623, 11077444 | | Comments | C-terminal PDZ domain-binding motif in the Ad9 E4-ORF1 oncoprotein which bind to PDZ1 and PDZ3 of MAGI-1 and inhibit its function in cells by aberrantly sequestering it to the cytoplasm |
Record No : 96 |
| Instance ID | 11506 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P03409 | | Bait Uniprot Identifier | TAX_HTL1A | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | SPR | | Interaction ID | 21506 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20842623 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) which binds to Human MAGI-1 |
Record No : 97 |
| Instance ID | 11507 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P14079 | | Bait Uniprot Identifier | TAX_HTL1C | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | SPR | | Interaction ID | 21507 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20842623 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) which binds to Human MAGI-1 |
Record No : 98 |
| Instance ID | 11508 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P0C213 | | Bait Uniprot Identifier | TAX_HTL1F | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | SPR | | Interaction ID | 21508 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20842623 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1) which binds to Human MAGI-1 |
Record No : 99 |
| Instance ID | 11509 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P03409 | | Bait Uniprot Identifier | TAX_HTL1A | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Differential display analysis | | Interaction ID | 21509 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15003862 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) which binds to MAGI-3 in Rat-1 cells |
Record No : 100 |
| Instance ID | 11510 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P14079 | | Bait Uniprot Identifier | TAX_HTL1C | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Differential display analysis | | Interaction ID | 21510 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15003862 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) which binds to MAGI-3 in Rat-1 cells |
Record No : 101 |
| Instance ID | 11511 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P0C213 | | Bait Uniprot Identifier | TAX_HTL1F | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Differential display analysis | | Interaction ID | 21511 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15003862 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1) which binds to MAGI-3 in Rat-1 cells |
Record No : 102 |
| Instance ID | 11512 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQL | | Bait Uniprot Accession | P03126 | | Bait Uniprot Identifier | VE6_HPV16 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 16 | | Sequence Position | 156-158 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down; Co-IP | | Interaction ID | 21512 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 9326658, 10523825 | | Comments | C terminal binding motif of E6 oncoprotein of Human papillomavirus type 16 that binds to the second PDZ domain of DLG and causes a dramatic reduction in the levels of DLG expression by targeting it for proteasome mediated degradation |
Record No : 103 |
| Instance ID | 11513 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TLV | | Bait Uniprot Accession | P89079 | | Bait Uniprot Identifier | E4OR1_ADE09 | | Bait Gene Name | E4 | | Bait Organism | Human adenovirus D serotype 9 (HAdV-9) (Human adenovirus 9) | | Sequence Position | 123-125 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21513 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 9192623 | | Comments | C-terminal PDZ domain-binding motif in the Ad9 E4-ORF1 oncoprotein that mediates its binding to hDLG/SAP97, the mammalian homolog for the Drosophila discs large tumor suppressor protein Dlg-A |
Record No : 104 |
| Instance ID | 11514 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P03409 | | Bait Uniprot Identifier | TAX_HTL1A | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21514 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 9192623 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) that is likely to bind to hDLG/SAP97, the mammalian homolog for the Drosophila discs large tumor suppressor protein Dlg-A |
Record No : 105 |
| Instance ID | 11515 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P14079 | | Bait Uniprot Identifier | TAX_HTL1C | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21515 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 9192623 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) that is likely to bind to hDLG/SAP97, the mammalian homolog for the Drosophila discs large tumor suppressor protein Dlg-A |
Record No : 106 |
| Instance ID | 11516 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P0C213 | | Bait Uniprot Identifier | TAX_HTL1F | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21516 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 9192623 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1) that is likely to bind to hDLG/SAP97, the mammalian homolog for the Drosophila discs large tumor suppressor protein Dlg-A |
Record No : 107 |
| Instance ID | 11517 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQL | | Bait Uniprot Accession | P03126 | | Bait Uniprot Identifier | VE6_HPV16 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 16 | | Sequence Position | 156-158 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down | | Interaction ID | 21517 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 17121805 | | Comments | Class I PDZ-domain binding motif in E6 oncoprotein of Human papillomavirus type 16 for binding and degradation of DLG4/PSD95 |
Record No : 108 |
| Instance ID | 11518 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQV | | Bait Uniprot Accession | P06463 | | Bait Uniprot Identifier | VE6_HPV18 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 18 | | Sequence Position | 156-158 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down | | Interaction ID | 21518 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 17121805 | | Comments | Class I PDZ-domain binding motif in E6 oncoprotein of Human papillomavirus type 18 for binding and degradation of DLG4/PSD95 |
Record No : 109 |
| Instance ID | 11519 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQL | | Bait Uniprot Accession | P03126 | | Bait Uniprot Identifier | VE6_HPV16 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 16 | | Sequence Position | 156-158 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21519 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 12140759 | | Comments | PDZ binding motif in E6 oncoprotein of Human papillomavirus type 16 for binding to MAGI-2 |
Record No : 110 |
| Instance ID | 11520 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQV | | Bait Uniprot Accession | P06463 | | Bait Uniprot Identifier | VE6_HPV18 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 18 | | Sequence Position | 156-158 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21520 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 12140759 | | Comments | PDZ binding motif in E6 oncoprotein of Human papillomavirus type 18 for binding to MAGI-2 |
Record No : 111 |
| Instance ID | 11521 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQL | | Bait Uniprot Accession | P03126 | | Bait Uniprot Identifier | VE6_HPV16 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 16 | | Sequence Position | 156-158 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21521 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 12140759 | | Comments | PDZ binding motif in E6 oncoprotein of Human papillomavirus type 16 for binding to the PDZ1 domain of MAGI-3 |
Record No : 112 |
| Instance ID | 11522 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQV | | Bait Uniprot Accession | P06463 | | Bait Uniprot Identifier | VE6_HPV18 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 18 | | Sequence Position | 156-158 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21522 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 12140759 | | Comments | PDZ binding motif in E6 oncoprotein of Human papillomavirus type 18 for binding to the PDZ1 domain of MAGI-3 |
Record No : 113 |
| Instance ID | 11523 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQL | | Bait Uniprot Accession | P03126 | | Bait Uniprot Identifier | VE6_HPV16 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 16 | | Sequence Position | 156-158 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21523 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11027293 | | Comments | PDZ binding epitope of E6 oncoprotein of Human papillomavirus type 16 that mediates its binding to the human homolog of the Drosophila PDZ domain-containing tumor suppressor protein Scribble, hScrib, which is associated with cell junction complexes |
Record No : 114 |
| Instance ID | 11524 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQV | | Bait Uniprot Accession | P24835 | | Bait Uniprot Identifier | VE6_HPV39 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 39 | | Sequence Position | 156-158 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21524 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11027293 | | Comments | PDZ binding epitope of E6 oncoprotein of Human papillomavirus type 39 that mediates its binding to the human homolog of the Drosophila PDZ domain-containing tumor suppressor protein Scribble, hScrib, which is associated with cell junction complexes |
Record No : 115 |
| Instance ID | 11525 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQV | | Bait Uniprot Accession | P06463 | | Bait Uniprot Identifier | VE6_HPV18 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 18 | | Sequence Position | 156-158 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21525 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 11000240 | | Comments | PDZ domain-binding motif in E6 oncoprotein of Human papillomavirus type 18 that mediates binding to the PDZ7 and PDZ10 domains of rat Mupp1 (Mpdz) |
Record No : 116 |
| Instance ID | 11526 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQL | | Bait Uniprot Accession | P03126 | | Bait Uniprot Identifier | VE6_HPV16 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 16 | | Sequence Position | 156-158 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21526 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16878151 | | Comments | PDZ binding motif in E6 oncoprotein of Human papillomavirus type 16 that binds to and promotes the degradation of CAL (GOPC) through the ubiquitin-proteasome pathway |
Record No : 117 |
| Instance ID | 11527 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQV | | Bait Uniprot Accession | P06463 | | Bait Uniprot Identifier | VE6_HPV18 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 18 | | Sequence Position | 156-158 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21527 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16878151 | | Comments | PDZ binding motif in E6 oncoprotein of Human papillomavirus type 18 that binds to and promotes the degradation of CAL (GOPC) through the ubiquitin-proteasome pathway |
Record No : 118 |
| Instance ID | 11528 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQL | | Bait Uniprot Accession | P03126 | | Bait Uniprot Identifier | VE6_HPV16 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 16 | | Sequence Position | 156-158 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21528 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17166906, 15492812 | | Comments | PDZ binding motif in E6 oncoprotein of Human papillomavirus type 16 which mediates the binding and degradation of the protein tyrosine phosphatase PTPN3 (PTPH1) |
Record No : 119 |
| Instance ID | 11529 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQV | | Bait Uniprot Accession | P06463 | | Bait Uniprot Identifier | VE6_HPV18 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 18 | | Sequence Position | 156-158 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Mutational analysis | | Interaction ID | 21529 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17166906, 15492812 | | Comments | PDZ binding motif in E6 oncoprotein of Human papillomavirus type 18 which mediates the binding and degradation of the protein tyrosine phosphatase PTPN3 (PTPH1) |
Record No : 120 |
| Instance ID | 11530 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQL | | Bait Uniprot Accession | P03126 | | Bait Uniprot Identifier | VE6_HPV16 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 16 | | Sequence Position | 156-158 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21530 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18160445 | | Comments | PDZ binding motif in E6 oncoprotein of Human papillomavirus type 16 that interacts with and induces loss of human PTPN13 |
Record No : 121 |
| Instance ID | 11531 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQL | | Bait Uniprot Accession | P03126 | | Bait Uniprot Identifier | VE6_HPV16 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 16 | | Sequence Position | 156-158 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21531 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18160445 | | Comments | PDZ binding motif in E6 oncoprotein of Human papillomavirus type 16 that interacts with and induces loss of mouse PTPN13 |
Record No : 122 |
| Instance ID | 11532 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQL | | Bait Uniprot Accession | P03126 | | Bait Uniprot Identifier | VE6_HPV16 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 16 | | Sequence Position | 156-158 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21532 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15492812 | | Comments | PDZ binding motif in E6 oncoprotein of Human papillomavirus type 16 for binding to Tax interacting protein 1 (Tip-1) [also known as Tax1-binding protein 3 (TAX1BP3)] |
Record No : 123 |
| Instance ID | 11533 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P03409 | | Bait Uniprot Identifier | TAX_HTL1A | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21533 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482110 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) which binds to Human TAX1BP3 |
Record No : 124 |
| Instance ID | 11534 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P14079 | | Bait Uniprot Identifier | TAX_HTL1C | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21534 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482110 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) which binds to Human TAX1BP3 |
Record No : 125 |
| Instance ID | 11535 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P0C213 | | Bait Uniprot Identifier | TAX_HTL1F | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21535 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482110 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1) which binds to Human TAX1BP3 |
Record No : 126 |
| Instance ID | 11536 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P03409 | | Bait Uniprot Identifier | TAX_HTL1A | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21536 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482110 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) which binds to Human DLG4 |
Record No : 127 |
| Instance ID | 11537 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P14079 | | Bait Uniprot Identifier | TAX_HTL1C | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21537 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482110 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) which binds to Human DLG4 |
Record No : 128 |
| Instance ID | 11538 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P0C213 | | Bait Uniprot Identifier | TAX_HTL1F | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21538 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482110 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1) which binds to Human DLG4 |
Record No : 129 |
| Instance ID | 11539 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P03409 | | Bait Uniprot Identifier | TAX_HTL1A | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21539 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482110 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) which binds to Human SNTB1 |
Record No : 130 |
| Instance ID | 11540 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P14079 | | Bait Uniprot Identifier | TAX_HTL1C | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21540 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482110 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) which binds to Human SNTB1 |
Record No : 131 |
| Instance ID | 11541 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P0C213 | | Bait Uniprot Identifier | TAX_HTL1F | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21541 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482110 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1) which binds to Human SNTB1 |
Record No : 132 |
| Instance ID | 11542 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P03409 | | Bait Uniprot Identifier | TAX_HTL1A | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21542 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482110 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) which binds to Human GIPC1 |
Record No : 133 |
| Instance ID | 11543 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P14079 | | Bait Uniprot Identifier | TAX_HTL1C | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21543 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482110 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) which binds to Human GIPC1 |
Record No : 134 |
| Instance ID | 11544 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TEV | | Bait Uniprot Accession | P0C213 | | Bait Uniprot Identifier | TAX_HTL1F | | Bait Gene Name | tax | | Bait Organism | Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1) | | Sequence Position | 351-353 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21544 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9482110 | | Comments | PDZ domain-binding motif in Tax1 oncoprotein of Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1) which binds to Human GIPC1 |
Record No : 135 |
| Instance ID | 11545 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQV | | Bait Uniprot Accession | P06463 | | Bait Uniprot Identifier | VE6_HPV18 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 18 | | Sequence Position | 156-158 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21545 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15767424 | | Comments | PDZ binding motif in E6 oncoprotein of Human papillomavirus type 18 which mediates the binding and degradation of human TIP-2/GIPC1 |
Record No : 136 |
| Instance ID | 11546 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQV | | Bait Uniprot Accession | P06463 | | Bait Uniprot Identifier | VE6_HPV18 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 18 | | Sequence Position | 156-158 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis | | Interaction ID | 21546 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17287269 | | Comments | PDZ binding motif in E6 oncoprotein of Human papillomavirus type 18 that binds to PDZ 4 and 5 and mediates the degradation of the tight junction-associated multi-PDZ protein PATJ (INADL) |
Record No : 137 |
| Instance ID | 11547 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TQL | | Bait Uniprot Accession | P03126 | | Bait Uniprot Identifier | VE6_HPV16 | | Bait Gene Name | E6 | | Bait Organism | Human papillomavirus type 16 | | Sequence Position | 156-158 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21547 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17287269 | | Comments | PDZ binding motif in E6 oncoprotein of Human papillomavirus type 16 that binds to and mediates the degradation of the tight junction-associated multi-PDZ protein PATJ (INADL) |
Record No : 138 |
| Instance ID | 11548 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SAI | | Bait Uniprot Accession | P48050 | | Bait Uniprot Identifier | KCNJ4_HUMAN | | Bait Gene Name | KCNJ4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 443-445 | | Critical Residues | P1 | | Motif PTM(s) | Phosphorylation at Ser-P1 | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Mutational analysis; Pull down(GST tag) | | Interaction ID | 21548 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8893032 | | Comments | PDZ domain binding C-terminal motif in Inward rectifier K(+) channel Kir2.3 protein (KCNJ4) that mediates binding to the PSD-95(DLG4) protein |
Record No : 139 |
| Instance ID | 11549 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SEI | | Bait Uniprot Accession | P63252 | | Bait Uniprot Identifier | KCNJ2_HUMAN | | Bait Gene Name | KCNJ2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 425-427 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21549 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8893032 | | Comments | PDZ domain binding C-terminal motif in Inward rectifier K(+) channel Kir2.1 protein (KCNJ2) that mediates binding to the PSD-95(DLG4) protein |
Record No : 140 |
| Instance ID | 11550 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TDV | | Bait Uniprot Accession | P22459 | | Bait Uniprot Identifier | KCNA4_HUMAN | | Bait Gene Name | KCNA4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 651-653 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Y2H | | Interaction ID | 21550 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8938729, 7477295 | | Comments | PDZ domain binding C-terminal motif in Voltage-gated potassium channel subunit Kv1.4 protein (KCNA4) which mediates binding to the PSD-95(DLG4) protein |
Record No : 141 |
| Instance ID | 11551 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TDV | | Bait Uniprot Accession | P22459 | | Bait Uniprot Identifier | KCNA4_HUMAN | | Bait Gene Name | KCNA4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 651-653 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21551 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8938729 | | Comments | PDZ domain binding C-terminal motif in Voltage-gated potassium channel subunit Kv1.4 protein (KCNA4) which mediates binding to the hDLG/SAP97 protein |
Record No : 142 |
| Instance ID | 11552 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TDV | | Bait Uniprot Accession | Q09470 | | Bait Uniprot Identifier | KCNA1_HUMAN | | Bait Gene Name | KCNA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 493-495 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21552 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8938729 | | Comments | PDZ domain binding C-terminal motif in Voltage-gated potassium channel subunit Kv1.1 protein (KCNA4) which mediates binding to the PSD-95(DLG4) protein |
Record No : 143 |
| Instance ID | 11553 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TDV | | Bait Uniprot Accession | P16389 | | Bait Uniprot Identifier | KCNA2_HUMAN | | Bait Gene Name | KCNA2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 497-499 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21553 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8938729 | | Comments | PDZ domain binding C-terminal motif in Voltage-gated potassium channel subunit Kv1.2 protein (KCNA4) which mediates binding to the PSD-95(DLG4) protein |
Record No : 144 |
| Instance ID | 11554 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TDV | | Bait Uniprot Accession | P22001 | | Bait Uniprot Identifier | KCNA3_HUMAN | | Bait Gene Name | KCNA3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 573-575 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21554 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8938729 | | Comments | PDZ domain binding C-terminal motif in Voltage-gated potassium channel subunit Kv1.3 protein (KCNA4) which mediates binding to the PSD-95(DLG4) protein |
Record No : 145 |
| Instance ID | 11555 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TVV | | Bait Uniprot Accession | Q05586 | | Bait Uniprot Identifier | NMDZ1_HUMAN | | Bait Gene Name | GRIN1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 883-885 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21555 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 7569905, 10336672 | | Comments | PDZ domain binding C-terminal motif in NR1-1 splice variant of NR1 subunit of the N-methyl-D-aspartate (NMDA) receptor (GRIN1) that binds to the second PDZ domain of PSD-95(DLG4) protein |
Record No : 146 |
| Instance ID | 11556 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SDV | | Bait Uniprot Accession | Q12879 | | Bait Uniprot Identifier | NMDE1_HUMAN | | Bait Gene Name | GRIN2A | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1462-1464 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21556 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 7569905, 10336672 | | Comments | PDZ domain binding C-terminal motif in NR2A subunit of the N-methyl-D-aspartate (NMDA) receptor (GRIN2A) that binds to the second PDZ domain of PSD-95(DLG4) protein |
Record No : 147 |
| Instance ID | 11557 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SDV | | Bait Uniprot Accession | Q13224 | | Bait Uniprot Identifier | NMDE2_HUMAN | | Bait Gene Name | GRIN2B | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1482-1484 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21557 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 7569905, 10336672 | | Comments | PDZ domain binding C-terminal motif in NR2B subunit of the N-methyl-D-aspartate (NMDA) receptor (GRIN2B) that binds to the second PDZ domain of PSD-95(DLG4) protein |
Record No : 148 |
| Instance ID | 11558 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SEV | | Bait Uniprot Accession | Q14957 | | Bait Uniprot Identifier | NMDE3_HUMAN | | Bait Gene Name | GRIN2C | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1231-1233 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21558 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 7569905, 10336672 | | Comments | PDZ domain binding C-terminal motif in NR2C subunit of the N-methyl-D-aspartate (NMDA) receptor (GRIN2C) that binds to the second PDZ domain of PSD-95(DLG4) protein |
Record No : 149 |
| Instance ID | 11559 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SEV | | Bait Uniprot Accession | O15399 | | Bait Uniprot Identifier | NMDE4_HUMAN | | Bait Gene Name | GRIN2D | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1334-1336 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21559 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 7569905, 10336672 | | Comments | PDZ domain binding C-terminal motif in NR2D subunit of the N-methyl-D-aspartate (NMDA) receptor (GRIN2D) that binds to the second PDZ domain of PSD-95(DLG4) protein |
Record No : 150 |
| Instance ID | 11560 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TVV | | Bait Uniprot Accession | Q05586 | | Bait Uniprot Identifier | NMDZ1_HUMAN | | Bait Gene Name | GRIN1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 883-885 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21560 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10336672 | | Comments | PDZ domain binding C-terminal motif in NR1-1 splice variant of NR1 subunit of the N-methyl-D-aspartate (NMDA) receptor (GRIN1) that binds to hDLG/SAP97 protein |
Record No : 151 |
| Instance ID | 11561 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SDV | | Bait Uniprot Accession | Q12879 | | Bait Uniprot Identifier | NMDE1_HUMAN | | Bait Gene Name | GRIN2A | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1462-1464 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21561 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10336672 | | Comments | PDZ domain binding C-terminal motif in NR2A subunit of the N-methyl-D-aspartate (NMDA) receptor (GRIN2A) that binds to hDLG/SAP97 protein |
Record No : 152 |
| Instance ID | 11562 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SDV | | Bait Uniprot Accession | Q13224 | | Bait Uniprot Identifier | NMDE2_HUMAN | | Bait Gene Name | GRIN2B | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1482-1484 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21562 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10336672 | | Comments | PDZ domain binding C-terminal motif in NR2B subunit of the N-methyl-D-aspartate (NMDA) receptor (GRIN2B) that binds to hDLG/SAP97 protein |
Record No : 153 |
| Instance ID | 11563 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SEV | | Bait Uniprot Accession | Q14957 | | Bait Uniprot Identifier | NMDE3_HUMAN | | Bait Gene Name | GRIN2C | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1231-1233 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21563 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10336672 | | Comments | PDZ domain binding C-terminal motif in NR2C subunit of the N-methyl-D-aspartate (NMDA) receptor (GRIN2C) that binds to hDLG/SAP97 protein |
Record No : 154 |
| Instance ID | 11564 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SEV | | Bait Uniprot Accession | O15399 | | Bait Uniprot Identifier | NMDE4_HUMAN | | Bait Gene Name | GRIN2D | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1334-1336 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21564 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10336672 | | Comments | PDZ domain binding C-terminal motif in NR2D subunit of the N-methyl-D-aspartate (NMDA) receptor (GRIN2D) that binds to hDLG/SAP97 protein |
Record No : 155 |
| Instance ID | 11565 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SSV | | Bait Uniprot Accession | P28335 | | Bait Uniprot Identifier | 5HT2C_HUMAN | | Bait Gene Name | HTR2C | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 456-458 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Y2H | | Interaction ID | 21565 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9537516 | | Comments | C-terminus of the human 5-HT2C receptor that may interact with PDZ domains of human Multi-PDZ domain protein 1 (MUPP1) or MPDZ |
Record No : 156 |
| Instance ID | 11566 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TGL | | Bait Uniprot Accession | P19490 | | Bait Uniprot Identifier | GRIA1_RAT | | Bait Gene Name | Gria1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 905-907 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography; Mutational analysis; Pull down(GST tag) | | Interaction ID | 21566 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9677374, 12070168, 17069616 | | Comments | The C-terminal type I PDZ binding motif in rat Glutamate receptor 1 (GluR1) or Gria1 that mediates its specific interaction with the second PDZ domain of rat Synapse-associated protein 97 (SAP97) or Disks large homolog 1 (Dlg1) |
Record No : 157 |
| Instance ID | 11567 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TTL | | Bait Uniprot Accession | P27732 | | Bait Uniprot Identifier | CAC1D_RAT | | Bait Gene Name | Cacna1d | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 2201-2203 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Y2H | | Interaction ID | 21567 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15689539 | | Comments | The C-terminal type I PDZ binding motif in rat Voltage-gated calcium channel subunit alpha Cav1.3 (Cacna1d) that mediates its specific interaction with the PDZ domain of rat Shank3 |
Record No : 158 |
| Instance ID | 11568 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TTL | | Bait Uniprot Accession | P27732 | | Bait Uniprot Identifier | CAC1D_RAT | | Bait Gene Name | Cacna1d | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 2201-2203 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21568 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15689539 | | Comments | The C-terminal type I PDZ binding motif in rat Voltage-gated calcium channel subunit alpha Cav1.3 (Cacna1d) that mediates its specific interaction with the PDZ domain of rat Shank1 |
Record No : 159 |
| Instance ID | 11569 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SNL | | Bait Uniprot Accession | Q01815 | | Bait Uniprot Identifier | CAC1C_MOUSE | | Bait Gene Name | Cacna1c | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 2137-2139 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21569 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the class C alpha1 subunit of a mouse brain calcium channel Cav1.2 (mbC alpha1) that mediates binding to the first PDZ domain of a large neuronal IL-16 precursor, NIL-16 |
Record No : 160 |
| Instance ID | 11570 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SNV | | Bait Uniprot Accession | Q9JM63 | | Bait Uniprot Identifier | KCJ10_MOUSE | | Bait Gene Name | Kcnj10 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 377-379 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21570 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the ATP-sensitive inward rectifier potassium channel Kir4.1 that mediates binding to the first PDZ domain of a large neuronal IL-16 precursor, NIL-16 |
Record No : 161 |
| Instance ID | 11571 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SNV | | Bait Uniprot Accession | Q91ZF1 | | Bait Uniprot Identifier | KCJ15_RAT | | Bait Gene Name | Kcnj15 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 403-405 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21571 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the ATP-sensitive inward rectifier potassium channel Kir4.2 that mediates binding to the first PDZ domain of a large neuronal IL-16 precursor, NIL-16 |
Record No : 162 |
| Instance ID | 11572 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SEI | | Bait Uniprot Accession | P35561 | | Bait Uniprot Identifier | KCNJ2_MOUSE | | Bait Gene Name | Kcnj2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 426-428 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21572 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the Inward rectifier potassium channel Kir2.1 that mediates binding to the large neuronal IL-16 precursor, NIL-16 |
Record No : 163 |
| Instance ID | 11573 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SRI | | Bait Uniprot Accession | P52189 | | Bait Uniprot Identifier | KCNJ4_MOUSE | | Bait Gene Name | Kcnj4 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 443-445 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21573 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the Inward rectifier potassium channel Kir2.3 that mediates binding to the large neuronal IL-16 precursor, NIL-16 |
Record No : 164 |
| Instance ID | 11574 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SSL | | Bait Uniprot Accession | Q03719 | | Bait Uniprot Identifier | KCND1_MOUSE | | Bait Gene Name | Kcnd1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 649-651 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21574 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the Voltage-gated potassium channel subunit Kv4.1 that mediates binding to the large neuronal IL-16 precursor, NIL-16 |
Record No : 165 |
| Instance ID | 11575 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SAL | | Bait Uniprot Accession | Q9Z0V2 | | Bait Uniprot Identifier | KCND2_MOUSE | | Bait Gene Name | Kcnd2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 628-630 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21575 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the Voltage-gated potassium channel subunit Kv4.2 that mediates binding to the large neuronal IL-16 precursor, NIL-16 |
Record No : 166 |
| Instance ID | 11576 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SAL | | Bait Uniprot Accession | Q9Z0V1 | | Bait Uniprot Identifier | KCND3_MOUSE | | Bait Gene Name | Kcnd3 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 653-655 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21576 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the Voltage-gated potassium channel subunit Kv4.3 that mediates binding to the large neuronal IL-16 precursor, NIL-16 |
Record No : 167 |
| Instance ID | 11577 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SDV | | Bait Uniprot Accession | P35436 | | Bait Uniprot Identifier | NMDE1_MOUSE | | Bait Gene Name | Grin2a | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 1462-1464 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21577 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the N-methyl D-aspartate receptor subtype 2A that mediates binding to the large neuronal IL-16 precursor, NIL-16 |
Record No : 168 |
| Instance ID | 11578 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SDV | | Bait Uniprot Accession | Q01097 | | Bait Uniprot Identifier | NMDE2_MOUSE | | Bait Gene Name | Grin2b | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 1480-1482 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21578 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the N-methyl D-aspartate receptor subtype 2B that mediates binding to the large neuronal IL-16 precursor, NIL-16 |
Record No : 169 |
| Instance ID | 11579 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SEV | | Bait Uniprot Accession | Q01098 | | Bait Uniprot Identifier | NMDE3_MOUSE | | Bait Gene Name | Grin2c | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 1237-1239 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21579 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the N-methyl D-aspartate receptor subtype 2C that mediates binding to the large neuronal IL-16 precursor, NIL-16 |
Record No : 170 |
| Instance ID | 11580 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SEV | | Bait Uniprot Accession | Q03391 | | Bait Uniprot Identifier | NMDE4_MOUSE | | Bait Gene Name | Grin2d | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 1321-1323 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21580 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the N-methyl D-aspartate receptor subtype 2D that mediates binding to the large neuronal IL-16 precursor, NIL-16 |
Record No : 171 |
| Instance ID | 11581 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SDV | | Bait Uniprot Accession | Q13641 | | Bait Uniprot Identifier | TPBG_HUMAN | | Bait Gene Name | TPBG | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 418-420 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis | | Interaction ID | 21581 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 11798178 | | Comments | Class I PDZ domain binding C-terminal motif in human 5T4 oncofetal trophoblast glycoprotein that is required for its interaction with PDZ domain-containing protein TIP-2/GIPC |
Record No : 172 |
| Instance ID | 11582 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TTV | | Bait Uniprot Accession | Q8JJ48 | | Bait Uniprot Identifier | DCT1A_XENLA | | Bait Gene Name | dact1-a | | Bait Organism | Xenopus laevis (African clawed frog) | | Sequence Position | 816-818 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; NMR | | Interaction ID | 21582 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14636582, 11941372 | | Comments | The C-terminal motif of Xenopus Dapper 1-A (or Frodo) that binds to the PDZ domain of the mouse cytoplasmic protein Dishevelled (Dvl) |
Record No : 173 |
| Instance ID | 11583 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TTV | | Bait Uniprot Accession | Q8QG92 | | Bait Uniprot Identifier | DCT1B_XENLA | | Bait Gene Name | dact1-b | | Bait Organism | Xenopus laevis (African clawed frog) | | Sequence Position | 822-824 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; NMR | | Interaction ID | 21583 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14636582, 11970895 | | Comments | The C-terminal motif of Xenopus Dapper 1-B that binds to the PDZ domain of the mouse cytoplasmic protein Dishevelled (Dvl) |
Record No : 174 |
| Instance ID | 11584 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TWL | | Bait Uniprot Accession | Q9EPK5 | | Bait Uniprot Identifier | WWTR1_MOUSE | | Bait Gene Name | Wwtr1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 393-395 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21584 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20850437 | | Comments | The carboxy-terminal PDZ binding motif of mouse WW domain-containing transcription regulator protein 1 (or Taz) that interacts with the Canis PDZ domain of Tight junction protein ZO-2 |
Record No : 175 |
| Instance ID | 11585 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TWL | | Bait Uniprot Accession | Q9EPK5 | | Bait Uniprot Identifier | WWTR1_MOUSE | | Bait Gene Name | Wwtr1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 393-395 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21585 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20850437 | | Comments | The carboxy-terminal PDZ binding motif of mouse WW domain-containing transcription regulator protein 1 (or Taz) that interacts with the Canis PDZ domain of Tight junction protein ZO-2 |
Record No : 176 |
| Instance ID | 11586 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TWL | | Bait Uniprot Accession | Q9EPK5 | | Bait Uniprot Identifier | WWTR1_MOUSE | | Bait Gene Name | Wwtr1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 393-395 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21586 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20850437 | | Comments | The carboxy-terminal PDZ binding motif of mouse WW domain-containing transcription regulator protein 1 (or Taz) that interacts with the human PDZ domain of Tight junction protein ZO-1 |
Record No : 177 |
| Instance ID | 11587 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TWL | | Bait Uniprot Accession | Q9EPK5 | | Bait Uniprot Identifier | WWTR1_MOUSE | | Bait Gene Name | Wwtr1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 393-395 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21587 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20850437 | | Comments | The carboxy-terminal PDZ binding motif of mouse WW domain-containing transcription regulator protein 1 (or Taz) that interacts with the human PDZ domain of Tight junction protein ZO-2 |
Record No : 178 |
| Instance ID | 11588 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TWL | | Bait Uniprot Accession | Q9GZV5 | | Bait Uniprot Identifier | WWTR1_HUMAN | | Bait Gene Name | WWTR1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 398-400 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21588 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20850437 | | Comments | The carboxy-terminal PDZ binding motif of human WW domain-containing transcription regulator protein 1 (or TAZ) that interacts with the human PDZ domain of Tight junction protein ZO-2 |
Record No : 179 |
| Instance ID | 11589 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TWL | | Bait Uniprot Accession | Q9GZV5 | | Bait Uniprot Identifier | WWTR1_HUMAN | | Bait Gene Name | WWTR1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 398-400 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21589 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20850437 | | Comments | The carboxy-terminal PDZ binding motif of human WW domain-containing transcription regulator protein 1 (or TAZ) that interacts with the human PDZ domain of Tight junction protein ZO-1 |
Record No : 180 |
| Instance ID | 11590 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TDL | | Bait Uniprot Accession | O95049 | | Bait Uniprot Identifier | ZO3_HUMAN | | Bait Gene Name | TJP3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 931-933 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21590 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12021270 | | Comments | The carboxyl terminus of ZO-3 (TJP3) that interacts with the 6th PDZ domain of PATJ (INADL) and is likely to be important for recruiting PATJ and its associated proteins to tight junctions |
Record No : 181 |
| Instance ID | 11591 | | Regular Expression | [DE]x[VLI]$ | | Motif Instance | DDV | | Bait Uniprot Accession | Q8IX03 | | Bait Uniprot Identifier | KIBRA_HUMAN | | Bait Gene Name | WWC1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1110-1113 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Y2H | | Interaction ID | 21591 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18596123 | | Comments | The C-terminal motif of KIBRA (WWC1) that directly interacts with the eighth PDZ domain of PATJ (INADL) |
Record No : 182 |
| Instance ID | 11592 | | Regular Expression | [DE]x[VLI]$ | | Motif Instance | DYV | | Bait Uniprot Accession | O95832 | | Bait Uniprot Identifier | CLD1_HUMAN | | Bait Gene Name | CLDN1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 209-211 | | Critical Residues | P2; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21592 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12021270 | | Comments | Claudin-1 carboxyl terminus that interacts with the 8th PDZ domain of PATJ (INADL) |
Record No : 183 |
| Instance ID | 11593 | | Regular Expression | [DE]x[VLI]$ | | Motif Instance | DYV | | Bait Uniprot Accession | O88551 | | Bait Uniprot Identifier | CLD1_MOUSE | | Bait Gene Name | Cldn1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 209-211 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag); Y2H | | Interaction ID | 21593 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11689568 | | Comments | Class III PDZ domain-binding motif of mouse claudin-1 that mediates binding to the PDZ10 of mouse Mupp1 (Mpdz) |
Record No : 184 |
| Instance ID | 11594 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | O88551 | | Bait Uniprot Identifier | CLD1_MOUSE | | Bait Gene Name | Cldn1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 210-211 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21594 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346, 11689568 | | Comments | The COOH-terminal YV sequence of mouse Claudin-1 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-1 (Tjp1) |
Record No : 185 |
| Instance ID | 11595 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | O88551 | | Bait Uniprot Identifier | CLD1_MOUSE | | Bait Gene Name | Cldn1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 210-211 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21595 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-1 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-2 (Tjp2) |
Record No : 186 |
| Instance ID | 11596 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | O88551 | | Bait Uniprot Identifier | CLD1_MOUSE | | Bait Gene Name | Cldn1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 210-211 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21596 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-1 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-3 (Tjp3) |
Record No : 187 |
| Instance ID | 11597 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | O88552 | | Bait Uniprot Identifier | CLD2_MOUSE | | Bait Gene Name | Cldn2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 229-230 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21597 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-2 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-1 (Tjp1) |
Record No : 188 |
| Instance ID | 11598 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | O88552 | | Bait Uniprot Identifier | CLD2_MOUSE | | Bait Gene Name | Cldn2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 229-230 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21598 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-2 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-2 (Tjp2) |
Record No : 189 |
| Instance ID | 11599 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | O88552 | | Bait Uniprot Identifier | CLD2_MOUSE | | Bait Gene Name | Cldn2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 229-230 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21599 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-2 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-3 (Tjp3) |
Record No : 190 |
| Instance ID | 11600 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | Q9Z0G9 | | Bait Uniprot Identifier | CLD3_MOUSE | | Bait Gene Name | Cldn3 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 218-219 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21600 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-3 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-1 (Tjp1) |
Record No : 191 |
| Instance ID | 11601 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | Q9Z0G9 | | Bait Uniprot Identifier | CLD3_MOUSE | | Bait Gene Name | Cldn3 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 218-219 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21601 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-3 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-2 (Tjp2) |
Record No : 192 |
| Instance ID | 11602 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | Q9Z0G9 | | Bait Uniprot Identifier | CLD3_MOUSE | | Bait Gene Name | Cldn3 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 218-219 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21602 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-3 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-3 (Tjp3) |
Record No : 193 |
| Instance ID | 11603 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | O35054 | | Bait Uniprot Identifier | CLD4_MOUSE | | Bait Gene Name | Cldn4 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 209-210 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21603 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-4 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-1 (Tjp1) |
Record No : 194 |
| Instance ID | 11604 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | O35054 | | Bait Uniprot Identifier | CLD4_MOUSE | | Bait Gene Name | Cldn4 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 209-210 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21604 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-4 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-2 (Tjp2) |
Record No : 195 |
| Instance ID | 11605 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | O35054 | | Bait Uniprot Identifier | CLD4_MOUSE | | Bait Gene Name | Cldn4 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 209-210 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21605 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-4 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-3 (Tjp3) |
Record No : 196 |
| Instance ID | 11606 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | O54942 | | Bait Uniprot Identifier | CLD5_MOUSE | | Bait Gene Name | Cldn5 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 217-218 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21606 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-5 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-1 (Tjp1) |
Record No : 197 |
| Instance ID | 11607 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | O54942 | | Bait Uniprot Identifier | CLD5_MOUSE | | Bait Gene Name | Cldn5 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 217-218 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21607 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-5 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-2 (Tjp2) |
Record No : 198 |
| Instance ID | 11608 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | O54942 | | Bait Uniprot Identifier | CLD5_MOUSE | | Bait Gene Name | Cldn5 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 217-218 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21608 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-5 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-3 (Tjp3) |
Record No : 199 |
| Instance ID | 11609 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | Q9Z262 | | Bait Uniprot Identifier | CLD6_MOUSE | | Bait Gene Name | Cldn6 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 218-219 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21609 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-6 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-1 (Tjp1) |
Record No : 200 |
| Instance ID | 11610 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | Q9Z262 | | Bait Uniprot Identifier | CLD6_MOUSE | | Bait Gene Name | Cldn6 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 218-219 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21610 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-6 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-2 (Tjp2) |
Record No : 201 |
| Instance ID | 11611 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | Q9Z262 | | Bait Uniprot Identifier | CLD6_MOUSE | | Bait Gene Name | Cldn6 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 218-219 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21611 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-6 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-3 (Tjp3) |
Record No : 202 |
| Instance ID | 11612 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | Q9Z261 | | Bait Uniprot Identifier | CLD7_MOUSE | | Bait Gene Name | Cldn7 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 210-211 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21612 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-7 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-1 (Tjp1) |
Record No : 203 |
| Instance ID | 11613 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | Q9Z261 | | Bait Uniprot Identifier | CLD7_MOUSE | | Bait Gene Name | Cldn7 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 210-211 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21613 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-7 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-2 (Tjp2) |
Record No : 204 |
| Instance ID | 11614 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | Q9Z261 | | Bait Uniprot Identifier | CLD7_MOUSE | | Bait Gene Name | Cldn7 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 210-211 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21614 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-7 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-3 (Tjp3) |
Record No : 205 |
| Instance ID | 11615 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | Q9Z260 | | Bait Uniprot Identifier | CLD8_MOUSE | | Bait Gene Name | Cldn8 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 224-225 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21615 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-8 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-1 (Tjp1) |
Record No : 206 |
| Instance ID | 11616 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | Q9Z260 | | Bait Uniprot Identifier | CLD8_MOUSE | | Bait Gene Name | Cldn8 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 224-225 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21616 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-8 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-2 (Tjp2) |
Record No : 207 |
| Instance ID | 11617 | | Regular Expression | YV$ | | Motif Instance | YV | | Bait Uniprot Accession | Q9Z260 | | Bait Uniprot Identifier | CLD8_MOUSE | | Bait Gene Name | Cldn8 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 224-225 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21617 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10601346 | | Comments | The COOH-terminal YV sequence of mouse Claudin-8 which mediates binding to the PDZ1 domain of mouse Tight junction protein ZO-3 (Tjp3) |
Record No : 208 |
| Instance ID | 11618 | | Regular Expression | [FY]x[VLI]$ | | Motif Instance | FLV | | Bait Uniprot Accession | Q9Y624 | | Bait Uniprot Identifier | JAM1_HUMAN | | Bait Gene Name | F11R | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 297-299 | | Critical Residues | P2; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis | | Interaction ID | 21618 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10877843, 11489913 | | Comments | The COOH-terminal class II PDZ-domain binding motif of human JAM (F11R) that directly interacts with PDZ3 domain of human Tight junction protein ZO-1 (TJP1) for recruitment of endogenous ZO-1 to cell–cell adhesion sites |
Record No : 209 |
| Instance ID | 11619 | | Regular Expression | [FY]x[VLI]$ | | Motif Instance | FLV | | Bait Uniprot Accession | Q9Y624 | | Bait Uniprot Identifier | JAM1_HUMAN | | Bait Gene Name | F11R | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 297-299 | | Critical Residues | P2; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis | | Interaction ID | 21619 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11489913 | | Comments | The COOH-terminal class II PDZ-domain binding motif of human JAM (F11R) that directly interacts with the PDZ domains of PAR-3 (PARD3) for recruitment of PAR-3 to cell–cell adhesion sites |
Record No : 210 |
| Instance ID | 11620 | | Regular Expression | [FY]x[VLI]$ | | Motif Instance | FLV | | Bait Uniprot Accession | O88792 | | Bait Uniprot Identifier | JAM1_MOUSE | | Bait Gene Name | F11r | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 299-300 | | Critical Residues | P2; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis | | Interaction ID | 21620 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11689568 | | Comments | The COOH-terminal class II PDZ-domain binding motif of mouse Jam (F11r) that specifically interacts with PDZ9 of mouse Mupp1 (Mpdz) for recruitment of Mupp1 to the cell-cell adhesion sites |
Record No : 211 |
| Instance ID | 11621 | | Regular Expression | [FY]x[VLI]$ | | Motif Instance | FLV | | Bait Uniprot Accession | O88792 | | Bait Uniprot Identifier | JAM1_MOUSE | | Bait Gene Name | F11r | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 299-300 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag); Y2H | | Interaction ID | 21621 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10856295 | | Comments | The COOH-terminal class II PDZ-domain binding motif of mouse Jam (F11r) that binds the PDZ domain of mouse ALL1-fused gene from chromosome 6(AF-6) protein/Afadin (Mllt4) |
Record No : 212 |
| Instance ID | 11622 | | Regular Expression | S[VLI]x[VLI]$ | | Motif Instance | SVKI | | Bait Uniprot Accession | P19491 | | Bait Uniprot Identifier | GRIA2_RAT | | Bait Gene Name | Gria2 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 880-883 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Y2H | | Interaction ID | 21622 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9069286 | | Comments | C-terminal PDZ domain-binding motif in the rat AMPA-selective glutamate receptor 2 (Gria2) that specifically interacts with PDZ domain 4 and 5 of the synaptic PDZ domain-containing protein Glutamate receptor-interacting protein 1 (Grip1) |
Record No : 213 |
| Instance ID | 11623 | | Regular Expression | S[VLI]x[VLI]$ | | Motif Instance | SVKI | | Bait Uniprot Accession | P19492 | | Bait Uniprot Identifier | GRIA3_RAT | | Bait Gene Name | Gria3 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 885-888 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Y2H | | Interaction ID | 21623 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9069286 | | Comments | C-terminal PDZ domain-binding motif in the rat AMPA-selective glutamate receptor 3 (Gria3) that specifically interacts with the synaptic PDZ domain-containing protein Glutamate receptor-interacting protein 1 (Grip1) |
Record No : 214 |
| Instance ID | 11624 | | Regular Expression | xSxV$ | | Motif Instance | ISNV | | Bait Uniprot Accession | P49655 | | Bait Uniprot Identifier | KCJ10_RAT | | Bait Gene Name | Kcnj10 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 376-379 | | Critical Residues | P2; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutational analysis | | Interaction ID | 21624 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9647694 | | Comments | C-terminal PDZ domain-binding motif in the rat ATP-sensitive inward rectifier potassium channel Kir4.1 (Kcnj10) that mediates its interaction with Channel-interacting PDZ domain-containing protein (or InaD-like protein) |
Record No : 215 |
| Instance ID | 11625 | | Regular Expression | xSxV$ | | Motif Instance | QSNV | | Bait Uniprot Accession | Q91ZF1 | | Bait Uniprot Identifier | KCJ15_RAT | | Bait Gene Name | Kcnj15 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 402-405 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21625 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9647694 | | Comments | C-terminal PDZ domain-binding motif in the rat ATP-sensitive inward rectifier potassium channel Kir4.2 (Kcnj15) that mediates its interaction with Channel-interacting PDZ domain-containing protein (or InaD-like protein) |
Record No : 216 |
| Instance ID | 11626 | | Regular Expression | xSxV$ | | Motif Instance | ESDV | | Bait Uniprot Accession | Q00959 | | Bait Uniprot Identifier | NMDE1_RAT | | Bait Gene Name | Grin2a | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1461-1464 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21626 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9647694 | | Comments | C-terminal PDZ domain-binding motif in the rat N-methyl D-aspartate receptor subtype 2A (Grin2a) that mediates its interaction with Channel-interacting PDZ domain-containing protein (or InaD-like protein) |
Record No : 217 |
| Instance ID | 11627 | | Regular Expression | xSxV$ | | Motif Instance | ESDV | | Bait Uniprot Accession | Q00960 | | Bait Uniprot Identifier | NMDE2_RAT | | Bait Gene Name | Grin2b | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1479-1482 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21627 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9647694 | | Comments | C-terminal PDZ domain-binding motif in the rat N-methyl D-aspartate receptor subtype 2B (Grin2b) that mediates its interaction with Channel-interacting PDZ domain-containing protein (or InaD-like protein) |
Record No : 218 |
| Instance ID | 11628 | | Regular Expression | xSxV$ | | Motif Instance | ESEV | | Bait Uniprot Accession | Q62644 | | Bait Uniprot Identifier | Q62644_RAT | | Bait Gene Name | Grin2c | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1247-1250 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21628 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9647694 | | Comments | C-terminal PDZ domain-binding motif in the rat N-methyl-D-aspartate receptor NMDAR2C subunit (Grin2c) that mediates its interaction with Channel-interacting PDZ domain-containing protein (or InaD-like protein) |
Record No : 219 |
| Instance ID | 11629 | | Regular Expression | xSxV$ | | Motif Instance | ESEV | | Bait Uniprot Accession | Q62645 | | Bait Uniprot Identifier | NMDE4_RAT | | Bait Gene Name | Grin2d | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1320-1323 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21629 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9647694 | | Comments | C-terminal PDZ domain-binding motif in the rat N-methyl D-aspartate receptor subtype 2D (Grin2d) that mediates its interaction with Channel-interacting PDZ domain-containing protein (or InaD-like protein) |
Record No : 220 |
| Instance ID | 11630 | | Regular Expression | SDA$ | | Motif Instance | SDA | | Bait Uniprot Accession | P11688 | | Bait Uniprot Identifier | ITA5_MOUSE | | Bait Gene Name | Itga5 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 1051-1053 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 21630 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11852236 | | Comments | C-terminal PDZ domain-binding motif in mouse Integrin alpha-5 that mediates its interaction with SEMCAP-1, the mouse homologue of TIP-2/GIPC |
Record No : 221 |
| Instance ID | 11631 | | Regular Expression | SDA$ | | Motif Instance | SDA | | Bait Uniprot Accession | Q61739 | | Bait Uniprot Identifier | ITA6_MOUSE | | Bait Gene Name | Itga6 (Isoform Alpha | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 1071-1073 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21631 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11852236 | | Comments | C-terminal PDZ domain-binding motif in mouse Integrin alpha-6 (Isoform Alpha-6X1A) that mediates its interaction with SEMCAP-1, the mouse homologue of TIP-2/GIPC |
Record No : 222 |
| Instance ID | 11632 | | Regular Expression | SYS$ | | Motif Instance | SYS | | Bait Uniprot Accession | Q61739 | | Bait Uniprot Identifier | ITA6_MOUSE | | Bait Gene Name | Itga6 (Isoform Alpha | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 1088-1091 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 21632 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11852236 | | Comments | C-terminal PDZ domain-binding motif in mouse Integrin alpha-6 (Isoform Alpha-6X1B) that mediates its interaction with SEMCAP-1, the mouse homologue of TIP-2/GIPC |
Record No : 223 |
| Instance ID | 11657 | | Regular Expression | [ST]x[VLI] | | Motif Instance | STV | | Bait Uniprot Accession | P19334 | | Bait Uniprot Identifier | TRP_DROME | | Bait Gene Name | trp | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 1264-1266 | | Critical Residues | P3 | | Motif PTM(s) | Phosphorylation at Ser-P1 | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Ligand Overlay Assay | | Interaction ID | 21657 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8630257 | | Comments | Internal class I PDZ-domain binding motif in Drosophila Transient receptor potential protein (trp) that binds to PDZ 3 (the second PDZ domain) of Drosophila Inactivation-no-after-potential D protein (inaD) |
Record No : 224 |
| Instance ID | 11658 | | Regular Expression | [YFG][YFHW][WFA]$ | | Motif Instance | FYA | | Bait Uniprot Accession | P18827 | | Bait Uniprot Identifier | SDC1_HUMAN | | Bait Gene Name | SDC1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 308-310 | | Critical Residues | P2; P3 | | Motif PTM(s) | Phosphorylation at Tyr-P2 | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; NMR; Fluorescence anisotropy binding assay | | Interaction ID | 21658 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20361982 | | Comments | Class II-type PDZ-binding motif in the C-terminal sequence of human Syndecan-1 that binds to the Tiam1 PDZ domain |
Record No : 225 |
| Instance ID | 11659 | | Regular Expression | [YFG][YFHW][WFA]$ | | Motif Instance | FYA | | Bait Uniprot Accession | P18827 | | Bait Uniprot Identifier | SDC1_HUMAN | | Bait Gene Name | SDC1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 308-310 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21659 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9660868 | | Comments | COOH-terminal sequence of human syndecan-1 that binds to the PDZ domain of hCASK |
Record No : 226 |
| Instance ID | 11660 | | Regular Expression | [YFG][YFHW][WFA]$ | | Motif Instance | FYA | | Bait Uniprot Accession | P34741 | | Bait Uniprot Identifier | SDC2_HUMAN | | Bait Gene Name | SDC2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 199-201 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 21660 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9660868 | | Comments | COOH-terminal sequence of human syndecan-2 that binds to the PDZ domain of hCASK |
Record No : 227 |
| Instance ID | 11661 | | Regular Expression | [YFG][YFHW][WFA]$ | | Motif Instance | FYA | | Bait Uniprot Accession | O75056 | | Bait Uniprot Identifier | SDC3_HUMAN | | Bait Gene Name | SDC3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 440-442 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21661 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9660868 | | Comments | COOH-terminal sequence of human syndecan-3 that may bind to the PDZ domain of hCASK |
Record No : 228 |
| Instance ID | 11662 | | Regular Expression | [YFG][YFHW][WFA]$ | | Motif Instance | FYA | | Bait Uniprot Accession | P31431 | | Bait Uniprot Identifier | SDC4_HUMAN | | Bait Gene Name | SDC4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 196-198 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21662 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9660868 | | Comments | COOH-terminal sequence of human syndecan-4 that may bind to the PDZ domain of hCASK |
Record No : 229 |
| Instance ID | 11663 | | Regular Expression | [YFG][YFHW][WFA]$ | | Motif Instance | FYA | | Bait Uniprot Accession | P34741 | | Bait Uniprot Identifier | SDC2_HUMAN | | Bait Gene Name | SDC2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 199-201 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | SPR; Mutational analysis; Y2H; Ligand blotting assay | | Interaction ID | 21663 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9391086 | | Comments | COOH-terminal sequence of human syndecan-2 that binds to both PDZ domains of human Syntenin-1 |
Record No : 230 |
| Instance ID | 11665 | | Regular Expression | [YFG][YFHW][WFA]$ | | Motif Instance | FYA | | Bait Uniprot Accession | P34901 | | Bait Uniprot Identifier | SDC4_RAT | | Bait Gene Name | Sdc4 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 200-202 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Y2H | | Interaction ID | 21665 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10911369 | | Comments | Class II-type PDZ-binding motif in the C-terminal sequence of rat cytoplasmic domain of syndecan-4 that binds to the mouse synectin (Gipc1) PDZ domain |
Record No : 231 |
| Instance ID | 11666 | | Regular Expression | [YFG][YFHW][WFA]$ | | Motif Instance | YFF | | Bait Uniprot Accession | Q9C0A0 | | Bait Uniprot Identifier | CNTP4_HUMAN | | Bait Gene Name | CNTNAP4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1306-1308 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; NMR; Fluorescence anisotropy binding assay | | Interaction ID | 21666 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20361982 | | Comments | Class II-type PDZ-binding motif in the C-terminal sequence of human Cell recognition molecule Caspr4 (CNTNAP4) that binds to the Tiam1 PDZ domain |
Record No : 232 |
| Instance ID | 11667 | | Regular Expression | D[ST]xL$ | | Motif Instance | DSLL | | Bait Uniprot Accession | P07550 | | Bait Uniprot Identifier | ADRB2_HUMAN | | Bait Gene Name | ADRB2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 410-413 | | Critical Residues | P1; P2; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Ligand Overlay Assay | | Interaction ID | 21667 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9560162, 9671706 | | Comments | C-terminal PDZ domain-binding motif in human Beta-2 adrenergic receptor that mediates binding to the first PDZ domain of the Na+/H+ exchanger regulatory factor (NHERF) and may play a role in beta2-adrenergic receptor-mediated regulation of Na+/H+ exchange |
Record No : 233 |
| Instance ID | 11668 | | Regular Expression | D[ST]xL$ | | Motif Instance | DTSL | | Bait Uniprot Accession | P47900 | | Bait Uniprot Identifier | P2RY1_HUMAN | | Bait Gene Name | P2RY1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 370-373 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Ligand Overlay Assay | | Interaction ID | 21668 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9671706 | | Comments | C-terminal PDZ domain-binding motif in human P2Y purinoceptor 1 (P2Y1) that mediates binding to the first PDZ domain of the Na+/H+ exchanger regulatory factor (NHERF) |
Record No : 234 |
| Instance ID | 11918 | | Regular Expression | HLETTF | | Motif Instance | HLETTF | | Bait Uniprot Accession | P29476 | | Bait Uniprot Identifier | NOS1_RAT | | Bait Gene Name | Nos1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 106-111 | | Critical Residues | P4; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Beta-hairpin finger | | Experimental Method(s) | X-ray crystallography; Mutational analysis; Fluorescence-based binding assay; Competition binding assay | | Interaction ID | 21918 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Becker’s muscular dystrophy | | Reference(s) | 11352727, 10221915 | | Comments | The PDZ protein interaction domain of rat neuronal nitric oxide synthase (nNOS) that binds to the syntrophin PDZ domain |
Record No : 235 |
| Instance ID | 11919 | | Regular Expression | HLETTF | | Motif Instance | HLETTF | | Bait Uniprot Accession | P29476 | | Bait Uniprot Identifier | NOS1_RAT | | Bait Gene Name | Nos1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 106-111 | | Critical Residues | P3; P4; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Beta-hairpin finger | | Experimental Method(s) | Mutational analysis; Y2H; Pull down(GST tag) | | Interaction ID | 21919 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Becker’s muscular dystrophy | | Reference(s) | 10488080 | | Comments | "An internal motif adjacent to the rat nNOS (Nos1) PDZ domain, a structured ""pseudo-peptide"" extension of the nNOS PDZ, that interacts with the peptide-binding pocket of rat PSD-95 (Dlg4) PDZ2 domain by a novel PDZ-PDZ interaction" |
Record No : 236 |
| Instance ID | 11948 | | Regular Expression | KTxxx[WI] | | Motif Instance | KTGHQI | | Bait Uniprot Accession | Q9EQC9 | | Bait Uniprot Identifier | CXXC4_RAT | | Bait Gene Name | Cxxc4 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 161-166 | | Critical Residues | P1; P2; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | NMR | | Interaction ID | 21948 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer; Alzheimer's disease | | Inhibitor(s) | Unknown | | Reference(s) | 15313210 | | Comments | Minimum region of Idax required for binding to PDZ domain of Dishevelled |
Record No : 237 |
| Instance ID | 11949 | | Regular Expression | KTxxx[WI] | | Motif Instance | KTCFEW | | Bait Uniprot Accession | O42579 | | Bait Uniprot Identifier | FZD3_XENLA | | Bait Gene Name | fzd3 | | Bait Organism | Xenopus laevis (African clawed frog) | | Sequence Position | 501-506 | | Critical Residues | P1; P2; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutational analysis | | Interaction ID | 21949 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10990458 | | Comments | A conserved internal motif sequence in the C-terminal cytoplasmic region of Xenopus membrane-bound receptor Frizzled-3 (Xfz3) that may bind to the conventional peptide binding site in the PDZ domain of the mouse cytoplasmic protein Dishevelled (Dvl) suggesting a role of this conserved motif in the modulation of Wnt signalling |
Record No : 238 |
| Instance ID | 11950 | | Regular Expression | KTxxx[WI] | | Motif Instance | KTLHTW | | Bait Uniprot Accession | Q9PT62 | | Bait Uniprot Identifier | FZD4_XENLA | | Bait Gene Name | fzd4 | | Bait Organism | Xenopus laevis (African clawed frog) | | Sequence Position | 485-490 | | Critical Residues | P1; P2; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21950 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10990458 | | Comments | A conserved internal motif sequence in the C-terminal cytoplasmic region of Xenopus membrane-bound receptor Frizzled-4 (Xfz4) that may bind to the conventional peptide binding site in the PDZ domain of the mouse cytoplasmic protein Dishevelled (Dvl) suggesting a role of this conserved motif in the modulation of Wnt signalling |
Record No : 239 |
| Instance ID | 11951 | | Regular Expression | KTxxx[WI] | | Motif Instance | KTLQSW | | Bait Uniprot Accession | Q9PUK8 | | Bait Uniprot Identifier | FZD7A_XENLA | | Bait Gene Name | fzd7-a | | Bait Organism | Xenopus laevis (African clawed frog) | | Sequence Position | 527-532 | | Critical Residues | P1; P2; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutational analysis | | Interaction ID | 21951 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10990458 | | Comments | A conserved internal motif sequence in the C-terminal cytoplasmic region of Xenopus membrane-bound receptor Frizzled-7-A (Xfz7-A) that may bind to the conventional peptide binding site in the PDZ domain of the mouse cytoplasmic protein Dishevelled (Dvl) suggesting a role of this conserved motif in the modulation of Wnt signalling |
Record No : 240 |
| Instance ID | 11952 | | Regular Expression | KTxxx[WI] | | Motif Instance | KTLQSW | | Bait Uniprot Accession | Q8AVJ9 | | Bait Uniprot Identifier | FZD7B_XENLA | | Bait Gene Name | fzd7-b | | Bait Organism | Xenopus laevis (African clawed frog) | | Sequence Position | 526-531 | | Critical Residues | P1; P2; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; NMR | | Interaction ID | 21952 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10990458, 14636582 | | Comments | A conserved internal motif sequence in the C-terminal cytoplasmic region of Xenopus membrane-bound receptor Frizzled-7-B (Xfz7-B) that binds to the conventional peptide binding site in the PDZ domain of the mouse cytoplasmic protein Dishevelled (Dvl) suggesting a role of this conserved motif in the modulation of Wnt signalling |
Record No : 241 |
| Instance ID | 11953 | | Regular Expression | KTxxx[WI] | | Motif Instance | KTMVSW | | Bait Uniprot Accession | P18537 | | Bait Uniprot Identifier | FRIZ_DROME | | Bait Gene Name | fz | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 556-561 | | Critical Residues | P1; P2; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21953 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10990458, 19234454 | | Comments | A conserved internal motif sequence in the C-terminal cytoplasmic region of Drosophila membrane-bound receptor Frizzled-1 (dFz1) that may bind to the conventional peptide binding site in the PDZ domain of the cytoplasmic protein Dishevelled (Dvl) suggesting a role of this conserved motif in the modulation of Wnt signalling |
Record No : 242 |
| Instance ID | 11954 | | Regular Expression | KTxxx[WI] | | Motif Instance | KTLESW | | Bait Uniprot Accession | Q9VVX3 | | Bait Uniprot Identifier | FRIZ2_DROME | | Bait Gene Name | fz2 | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 608-613 | | Critical Residues | P1; P2; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21954 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10990458, 14636582 | | Comments | A conserved internal motif sequence in the C-terminal cytoplasmic region of Drosophila membrane-bound receptor Frizzled-2 (dFz2) that may bind to the conventional peptide binding site in the PDZ domain of the cytoplasmic protein Dishevelled (Dvl) suggesting a role of this conserved motif in the modulation of Wnt signalling |
Record No : 243 |
| Instance ID | 12018 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | QRYSDF | | Bait Uniprot Accession | Q9AJU4 | | Bait Uniprot Identifier | Q9AJU4_SHIFL | | Bait Gene Name | ospE1 | | Bait Organism | Shigella flexneri | | Sequence Position | 86-88 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Pull down(GST tag) | | Interaction ID | 22018 | | Interacting Domain | PDZ domain | | Disease Association(s) | Shigellosis | | Inhibitor(s) | Unknown | | Reference(s) | 25124035 | | Comments | C-terminal class 1 PDZ-binding motif in the effector protein OspE1 of Shigella flexneri serotype 2a strain 2457T that mediates its interaction with human PDZ and LIM domain protein 7 (PDLIM7/ENIGMA), leading to activation of isoforms of protein kinase C (PKC) |
Record No : 244 |
| Instance ID | 12019 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | QRYSDF | | Bait Uniprot Accession | Q9AJW6 | | Bait Uniprot Identifier | Q9AJW6_SHIFL | | Bait Gene Name | ospE2 | | Bait Organism | Shigella flexneri | | Sequence Position | 83-88 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 22019 | | Interacting Domain | PDZ domain | | Disease Association(s) | Shigellosis | | Inhibitor(s) | Unknown | | Reference(s) | 25124035 | | Comments | C-terminal class 1 PDZ-binding motif in the effector protein OspE2 of Shigella flexneri serotype 2a strain 2457T that mediates its interaction with human PDZ and LIM domain protein 7 (PDLIM7/ENIGMA) |
Record No : 245 |
| Instance ID | 12020 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | QRYSDF | | Bait Uniprot Accession | Q9AJU4 | | Bait Uniprot Identifier | Q9AJU4_SHIFL | | Bait Gene Name | ospE1 | | Bait Organism | Shigella flexneri | | Sequence Position | 86-88 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Fluorescence polarization | | Interaction ID | 22020 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25124035 | | Comments | C-terminal class 1 PDZ-binding motif in the effector protein OspE1 of Shigella flexneri serotype 2a strain 2457T that mediates its interaction with human PDZ and LIM domain protein 3 (PDLIM3) |
Record No : 246 |
| Instance ID | 12021 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | QRYSDF | | Bait Uniprot Accession | Q9AJU4 | | Bait Uniprot Identifier | Q9AJU4_SHIFL | | Bait Gene Name | ospE1 | | Bait Organism | Shigella flexneri | | Sequence Position | 86-88 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Fluorescence polarization | | Interaction ID | 22021 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25124035 | | Comments | C-terminal class 1 PDZ-binding motif in the effector protein OspE1 of Shigella flexneri serotype 2a strain 2457T that mediates its interaction with human MAGI1 |
Record No : 247 |
| Instance ID | 12028 | | Regular Expression | x[DEKR]x[ACVILFM]$ | | Motif Instance | GRRF | | Bait Uniprot Accession | P09651 | | Bait Uniprot Identifier | ROA1_HUMAN | | Bait Gene Name | HNRNPA1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 369-372 | | Critical Residues | P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | ELISA; Pull down | | Interaction ID | 22028 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25009770 | | Comments | The carboxy-terminal PDZ binding motif of human Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) that interacts with the human 26S proteasome non-ATPase regulatory subunit 9 (PSMD9) |
Record No : 248 |
| Instance ID | 12029 | | Regular Expression | x[DEKR]x[ACVILFM]$ | | Motif Instance | SCGF | | Bait Uniprot Accession | P0DML2 | | Bait Uniprot Identifier | CSH1_HUMAN | | Bait Gene Name | CSH1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 214-217 | | Critical Residues | P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | ELISA; Pull down | | Interaction ID | 22029 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25009770 | | Comments | The carboxy-terminal PDZ binding motif of human Chorionic somatomammotropin hormone 1 (CSH1) that interacts with the human 26S proteasome non-ATPase regulatory subunit 9 (PSMD9) |
Record No : 249 |
| Instance ID | 12030 | | Regular Expression | x[DEKR]x[ACVILFM]$ | | Motif Instance | AGHM | | Bait Uniprot Accession | P15923 | | Bait Uniprot Identifier | TFE2_HUMAN | | Bait Gene Name | TCF3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 651-654 | | Critical Residues | P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | ELISA; Pull down | | Interaction ID | 22030 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25009770 | | Comments | The carboxy-terminal PDZ binding motif of human Transcription factor E2-alpha/ Transcription factor 3 (TCF3) that interacts with the human 26S proteasome non-ATPase regulatory subunit 9 (PSMD9) |
Record No : 250 |
| Instance ID | 12048 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | SVGTHC | | Bait Uniprot Accession | O15354 | | Bait Uniprot Identifier | GPR37_HUMAN | | Bait Gene Name | GPR37 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 608-613 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 22048 | | Interacting Domain | PDZ domain | | Disease Association(s) | Parkinson's disease | | Inhibitor(s) | Unknown | | Reference(s) | 24749734 | | Comments | C-terminal class 1 PDZ-binding motif in human Prosaposin receptor GPR37 that binds to the PDZ domain of human PRKCA-binding protein (PICK1) |
Record No : 251 |
| Instance ID | 12058 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | SKEAYI | | Bait Uniprot Accession | P31648 | | Bait Uniprot Identifier | SC6A1_MOUSE | | Bait Gene Name | Slc6a1 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 594-599 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down | | Interaction ID | 22058 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25305483 | | Comments | C-terminal class 1 PDZ-binding motif in mouse Sodium- and chloride-dependent GABA transporter 1 (Slc6a1) that binds to the PDZ domains of mouse Multiple PDZ domain protein (Mpdz) |
Record No : 252 |
| Instance ID | 12059 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | EKETHL | | Bait Uniprot Accession | P31651 | | Bait Uniprot Identifier | S6A12_MOUSE | | Bait Gene Name | Slc6a12 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 609-614 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down | | Interaction ID | 22059 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25305483 | | Comments | C-terminal class 1 PDZ-binding motif in mouse Sodium- and chloride-dependent GABA transporter 2 (Slc6a12) that binds to the PDZ domains of mouse Multiple PDZ domain protein (Mpdz) |
Record No : 253 |
| Instance ID | 12060 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | EKETHF | | Bait Uniprot Accession | P31650 | | Bait Uniprot Identifier | S6A11_MOUSE | | Bait Gene Name | Slc6a11 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 622-627 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down | | Interaction ID | 22060 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25305483 | | Comments | C-terminal class 1 PDZ-binding motif in mouse Sodium- and chloride-dependent GABA transporter 3 (Slc6a11) that binds to the PDZ domains of mouse Multiple PDZ domain protein (Mpdz) |
Record No : 254 |
| Instance ID | 12061 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | FQDSRI | | Bait Uniprot Accession | P28571 | | Bait Uniprot Identifier | SC6A9_MOUSE | | Bait Gene Name | Slc6a9 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 687-692 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down | | Interaction ID | 22061 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25305483 | | Comments | C-terminal class 1 PDZ-binding motif in mouse Sodium- and chloride-dependent glycine transporter 1 (Slc6a9) that binds to the PDZ domains of mouse Multiple PDZ domain protein (Mpdz) |
Record No : 255 |
| Instance ID | 12062 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | ELGTQC | | Bait Uniprot Accession | Q761V0 | | Bait Uniprot Identifier | SC6A5_MOUSE | | Bait Gene Name | Slc6a5 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 794-799 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down | | Interaction ID | 22062 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25305483 | | Comments | C-terminal class 1 PDZ-binding motif in mouse Sodium- and chloride-dependent glycine transporter 2 (Slc6a5) that binds to the PDZ domains of mouse Multiple PDZ domain protein (Mpdz) |
Record No : 256 |
| Instance ID | 12068 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | EKSTKL | | Bait Uniprot Accession | O43572 | | Bait Uniprot Identifier | AKA10_HUMAN | | Bait Gene Name | AKAP10 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 657-662 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | X-ray crystallography; Peptide Array Screening | | Interaction ID | 22068 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25348485 | | Comments | The six C-terminal residues of human Dual specificity A kinase-anchoring protein 2 (D-AKAP-2) or AKAP10 represent a C-terminal class 1 PDZ-binding motif that binds to the third and fourth PDZ domains of human Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (PDZK1) |
Record No : 257 |
| Instance ID | 12069 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | EKSTKL | | Bait Uniprot Accession | O43572 | | Bait Uniprot Identifier | AKA10_HUMAN | | Bait Gene Name | AKAP10 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 657-662 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Peptide Array Screening | | Interaction ID | 22069 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25348485 | | Comments | The six C-terminal residues of human Dual specificity A kinase-anchoring protein 2 (D-AKAP-2) or AKAP10 represent a C-terminal class 1 PDZ-binding motif that binds to the third and fourth PDZ domains of human Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (SLC9A3R1) |
Record No : 258 |
| Instance ID | 12070 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | EKSTKL | | Bait Uniprot Accession | O43572 | | Bait Uniprot Identifier | AKA10_HUMAN | | Bait Gene Name | AKAP10 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 657-662 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Peptide Array Screening | | Interaction ID | 22070 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25348485 | | Comments | The six C-terminal residues of human Dual specificity A kinase-anchoring protein 2 (D-AKAP-2) or AKAP10 represent a C-terminal class 1 PDZ-binding motif that binds to the third and fourth PDZ domains of human Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (SLC9A3R2) |
Record No : 259 |
| Instance ID | 12073 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | HTSTTL | | Bait Uniprot Accession | P25025 | | Bait Uniprot Identifier | CXCR2_HUMAN | | Bait Gene Name | CXCR2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 355-360 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Pull down(GST tag) | | Interaction ID | 22073 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 23544174 | | Comments | The C-terminal class 1 PDZ-binding motif in human C-X-C chemokine receptor type 2 (CXCR2) that binds to the PDZ domains of human Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (SLC9A3R1) |
Record No : 260 |
| Instance ID | 12174 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | VIATEV | | Bait Uniprot Accession | O00548 | | Bait Uniprot Identifier | DLL1_HUMAN | | Bait Gene Name | DLL1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 718-723 | | Critical Residues | P3; P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 22174 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 24025447 | | Comments | C-terminal class 1 PDZ-binding motif in human Delta-like protein 1 (DLL1) that binds to the PDZ domain of human Synaptojanin-2-binding protein (SYNJ2BP) |
Record No : 261 |
| Instance ID | 12175 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | VIATEV | | Bait Uniprot Accession | Q9NR61 | | Bait Uniprot Identifier | DLL4_HUMAN | | Bait Gene Name | DLL4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 680-685 | | Critical Residues | P3; P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 22175 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 24025447 | | Comments | C-terminal class 1 PDZ-binding motif in human Delta-like protein 4 (DLL4) that binds to the PDZ domain of human Synaptojanin-2-binding protein (SYNJ2BP) |
Record No : 262 |
| Instance ID | 12176 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | VIATEV | | Bait Uniprot Accession | O00548 | | Bait Uniprot Identifier | DLL1_HUMAN | | Bait Gene Name | DLL1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 718-723 | | Critical Residues | P3; P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 22176 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 24025447 | | Comments | C-terminal class 1 PDZ-binding motif in human Delta-like protein 1 (DLL1) that binds to the PDZ domain of human Multiple PDZ domain protein (MPDZ/MUPP1) |
Record No : 263 |
| Instance ID | 12177 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | VIATEV | | Bait Uniprot Accession | Q9NR61 | | Bait Uniprot Identifier | DLL4_HUMAN | | Bait Gene Name | DLL4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 680-685 | | Critical Residues | P3; P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 22177 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 24025447 | | Comments | C-terminal class 1 PDZ-binding motif in human Delta-like protein 4 (DLL4) that binds to the PDZ domain of human Multiple PDZ domain protein (MPDZ/MUPP1) |
Record No : 264 |
| Instance ID | 12178 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | VIATEV | | Bait Uniprot Accession | O00548 | | Bait Uniprot Identifier | DLL1_HUMAN | | Bait Gene Name | DLL1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 718-723 | | Critical Residues | P3; P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 22178 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 24025447 | | Comments | C-terminal class 1 PDZ-binding motif in human Delta-like protein 1 (DLL1) that binds to the PDZ domain of human Membrane-associated guanylate kinase inverted 2 (MAGI2) |
Record No : 265 |
| Instance ID | 12179 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | VIATEV | | Bait Uniprot Accession | Q9NR61 | | Bait Uniprot Identifier | DLL4_HUMAN | | Bait Gene Name | DLL4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 680-685 | | Critical Residues | P3; P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 22179 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 24025447 | | Comments | C-terminal class 1 PDZ-binding motif in human Delta-like protein 4 (DLL4) that binds to the PDZ domain of human Membrane-associated guanylate kinase inverted 2 (MAGI2) |
Record No : 266 |
| Instance ID | 12180 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | VIATEV | | Bait Uniprot Accession | O00548 | | Bait Uniprot Identifier | DLL1_HUMAN | | Bait Gene Name | DLL1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 718-723 | | Critical Residues | P3; P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 22180 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 24025447 | | Comments | C-terminal class 1 PDZ-binding motif in human Delta-like protein 1 (DLL1) that binds to the PDZ domain of human Membrane-associated guanylate kinase inverted 3 (MAGI3) |
Record No : 267 |
| Instance ID | 12181 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | VIATEV | | Bait Uniprot Accession | Q9NR61 | | Bait Uniprot Identifier | DLL4_HUMAN | | Bait Gene Name | DLL4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 680-685 | | Critical Residues | P3; P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 22181 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 24025447 | | Comments | C-terminal class 1 PDZ-binding motif in human Delta-like protein 4 (DLL4) that binds to the PDZ domain of human Membrane-associated guanylate kinase inverted 3 (MAGI3) |
Record No : 268 |
| Instance ID | 12185 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | DLQTEV | | Bait Uniprot Accession | O14514 | | Bait Uniprot Identifier | BAI1_HUMAN | | Bait Gene Name | BAI1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1579-1584 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | PDZ Domain Proteomic Array | | Interaction ID | 22185 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 23782696 | | Comments | C-terminal class 1 PDZ-binding motif in human Brain-specific angiogenesis inhibitor 1 (BAI1) that binds to the PDZ1 and PDZ2 domains of human Disks large homolog 4 (DLG4/PSD95) |
Record No : 269 |
| Instance ID | 12186 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | DLQTEV | | Bait Uniprot Accession | O14514 | | Bait Uniprot Identifier | BAI1_HUMAN | | Bait Gene Name | BAI1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1579-1584 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | PDZ Domain Proteomic Array | | Interaction ID | 22186 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 23782696 | | Comments | C-terminal class 1 PDZ-binding motif in human Brain-specific angiogenesis inhibitor 1 (BAI1) that binds to the PDZ4 and PDZ5 domains of human Membrane-associated guanylate kinase inverted 1 (MAGI-1) |
Record No : 270 |
| Instance ID | 12187 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | DLQTEV | | Bait Uniprot Accession | O14514 | | Bait Uniprot Identifier | BAI1_HUMAN | | Bait Gene Name | BAI1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1579-1584 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Pull down(GST tag); PDZ Domain Proteomic Array | | Interaction ID | 22187 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 23782696 | | Comments | C-terminal class 1 PDZ-binding motif in human Brain-specific angiogenesis inhibitor 1 (BAI1) that binds to the PDZ domain of human Membrane-associated guanylate kinase inverted 2 (MAGI2) |
Record No : 271 |
| Instance ID | 12188 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | DLQTEV | | Bait Uniprot Accession | O14514 | | Bait Uniprot Identifier | BAI1_HUMAN | | Bait Gene Name | BAI1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1579-1584 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | PDZ Domain Proteomic Array | | Interaction ID | 22188 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 23782696 | | Comments | C-terminal class 1 PDZ-binding motif in human Brain-specific angiogenesis inhibitor 1 (BAI1) that binds to the PDZ domain of human Membrane-associated guanylate kinase inverted 3 (MAGI3) |
Record No : 272 |
| Instance ID | 12189 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | DLQTEV | | Bait Uniprot Accession | O14514 | | Bait Uniprot Identifier | BAI1_HUMAN | | Bait Gene Name | BAI1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1579-1584 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | PDZ Domain Proteomic Array | | Interaction ID | 22189 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 23782696 | | Comments | C-terminal class 1 PDZ-binding motif in human Brain-specific angiogenesis inhibitor 1 (BAI1) that binds to the PDZ domain of human InaD-like protein (INADL) |
Record No : 273 |
| Instance ID | 12190 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | DLQTEV | | Bait Uniprot Accession | O14514 | | Bait Uniprot Identifier | BAI1_HUMAN | | Bait Gene Name | BAI1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1579-1584 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | PDZ Domain Proteomic Array | | Interaction ID | 22190 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 23782696 | | Comments | C-terminal class 1 PDZ-binding motif in human Brain-specific angiogenesis inhibitor 1 (BAI1) that binds to the PDZ domain of human Disks large homolog 1 (DLG1/SAP97) |
Record No : 274 |
| Instance ID | 12205 | | Regular Expression | [ST]x[VL]$ | | Motif Instance | TRV | | Bait Uniprot Accession | Q9Y5I7 | | Bait Uniprot Identifier | CLD16_HUMAN | | Bait Gene Name | CLDN16 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 303-305 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down; Co-IP | | Interaction ID | 22205 | | Interacting Domain | PDZ domain | | Disease Association(s) | Familial hypomagnesemia with hypercalciuria and ne | | Inhibitor(s) | Unknown | | Reference(s) | 14628289 | | Comments | C-terminal putative type 1 PDZ-binding motif in human renal tight junction protein Claudin-16 whose mutation abolishes binding to the human scaffolding protein ZO-1 resulting in its lysosomal mislocalization and is associated with childhood hypercalciuria |
|
