Instance ID10029
Regular ExpressionRxx[^P]([ST])[IVLM]x
Motif InstanceRRAASMD
Bait Uniprot AccessionP98177
Bait Uniprot IdentifierFOXO4_HUMAN
Bait Gene NameFOXO4
Bait OrganismHomo sapiens (Human)
Sequence Position193-199
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down; Mutation analysis
Interaction ID20029
Interacting Domain14-3-3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16114898
Comments14-3-3 protein zeta interaction with nuclear localization sequence of human forkhead transcription factor FoxO4 could inhibit interaction between FoxO4 and nuclear importing machinery and thus shift the equilibrium of FoxO4 localization toward the cytoplasm

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)