Instance ID10032
Regular ExpressionRxx[^P]([ST])[IVLM]x
Motif InstanceRLRRSLP
Bait Uniprot AccessionQ14432
Bait Uniprot IdentifierPDE3A_HUMAN
Bait Gene NamePDE3A
Bait OrganismHomo sapiens (Human)
Sequence Position424-430
Critical ResiduesP5
Motif PTM(s)Phosphorylation at Ser-P5
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Pull down
Interaction ID20032
Interacting Domain14-3-3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16153182
CommentsPDE3A (phosphodiesterase 3A) binds directly to BMH2 (the 14-3-3 isoform from Saccharomyces cerevisiae) in a phosphorylation-dependent manner upon phosphorylation of Ser428

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)