Instance ID10038
Regular ExpressionRxx[^P]([ST])[IVLM]x
Motif InstanceRRSLTVG
Bait Uniprot AccessionP08965
Bait Uniprot IdentifierMEI2_SCHPO
Bait Gene Namemei2
Bait OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Sequence Position523-529
Critical ResiduesP5
Motif PTM(s)Phosphorylation at Thr-P5
Secondary StructureUnknown
Experimental Method(s)Co-IP; Y2H; Competition binding; Mutation analysis
Interaction ID20038
Interacting Domain14-3-3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11818066
CommentsRad24p, a 14-3-3 protein, functions as a negative factor for meiosis by antagonizing the binding of RNA to the phosphorylated form of fission yeast meiotic regulator Mei2p at Thr527

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)