Instance ID10072
Regular Expression[RHK][STALV]x([ST])x[PESRDIFTQ]
Motif InstanceRSRSCR
Bait Uniprot AccessionP04233
Bait Uniprot IdentifierHG2A_HUMAN
Bait Gene NameCD74
Bait OrganismHomo sapiens (Human)
Sequence Position5-10
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Co-IP; Mutation analysis
Interaction ID20072
Interacting Domain14-3-3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9448284
Comments14-3-3 binding site (pS-8) in the human HLA class II histocompatibility antigen gamma chain (CD74) that mediates binding to 14-3-3 protein eta

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)