|
| Instance ID | 10088 | | Regular Expression | [R]xx[ILVMF][ILMVF][^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATI] | | Motif Instance | RDALLGDIRKGMKLKKA | | Bait Uniprot Accession | P37370 | | Bait Uniprot Identifier | VRP1_YEAST | | Bait Gene Name | VRP1 | | Bait Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | | Sequence Position | 31-47 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Classical fluorescence spectroscopy; Y2H; Mutation analysis; GFP tag | | Interaction ID | 20088 | | Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9412475 | | Comments | WH2 motif in Yeast verprolin, encoded by VRP1, that binds to the hydrophobic cleft formed by subdomains 1 and 3 of Yeast Actin, thus allowing Verprolin to serve as a polarity development protein, perhaps by anchoring actin |
|
