Instance ID10093
Regular Expression[R]xx[ILVMF][ILMVF][^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATI]
Motif InstanceRGALLDQIRQGIQLNKT
Bait Uniprot AccessionP42768
Bait Uniprot IdentifierWASP_HUMAN
Bait Gene NameWAS
Bait OrganismHomo sapiens (Human)
Sequence Position431-447
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutation analysis; Fluorescence polarization spectroscopy; ITC; circular dichroism; X-ray crystallography; structure based prediction; Sequence based prediction
Interaction ID20093
Interacting DomainHydrophobic cleft formed by subdomains 1 and 3
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11146629, 16275905
CommentsWH2 motif in human Wiskott-Aldrich syndrome protein that binds to the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)