Instance ID10098
Regular Expression[^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS]
Motif InstanceNPELQSAIGQGAALKHA
Bait Uniprot AccessionP18281
Bait Uniprot IdentifierACTO_ACACA
Bait Gene NameNot Available
Bait OrganismAcanthamoeba castellanii (Amoeba)
Sequence Position2-18
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutation analysis; Cross linking studies
Interaction ID20098
Interacting DomainHydrophobic cleft formed by subdomains 1 and 3
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)1464307
CommentsThe actin binding site of Acanthamoeba protein Actobindin that mediates its interaction with the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)