Instance ID10100
Regular Expression[^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS]
Motif InstanceQQSIFEGITAFNQNNLKHT
Bait Uniprot AccessionO97428
Bait Uniprot IdentifierO97428_DROME
Bait Gene Namecib
Bait OrganismDrosophila melanogaster (Fruit fly)
Sequence Position53-71
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Subcellular preparation; Cross linking studies; ITC; Structure based prediction; Sequence based prediction; X-ray crystallography
Interaction ID20100
Interacting DomainHydrophobic cleft formed by subdomains 1 and 3
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11030623, 16275905
CommentsThe WH2 motif (53-71) in Drosophila ciboulot that mediates its interaction with the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)