Instance ID10102
Regular Expression[^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS]
Motif InstanceHAMILEFIRSRPPLKKA
Bait Uniprot AccessionQ9U1K1
Bait Uniprot IdentifierSPIR_DROME
Bait Gene Namespir
Bait OrganismDrosophila melanogaster (Fruit fly)
Sequence Position432-448
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Affinity chromatography technology; Mutation analysis; Electron microscopy; Pull down; Alanine scanning
Interaction ID20102
Interacting DomainHydrophobic cleft formed by subdomains 1 and 3
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15674283
CommentsWH2 motif (432-448) in Drosophila protein Spire that binds to the hydrophobic cleft formed by subdomains 1 and 3 of Acanthamoeba Actin-1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)