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Instance ID | 10106 |
Regular Expression | [^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS] |
Motif Instance | YEILMGDIRAKKYQLRKV |
Bait Uniprot Accession | Q9U1K1 |
Bait Uniprot Identifier | SPIR_DROME |
Bait Gene Name | spir |
Bait Organism | Drosophila melanogaster (Fruit fly) |
Sequence Position | 400-417 |
Critical Residues | Unknown |
Motif PTM(s) | Unknown |
Secondary Structure | Disordered |
Experimental Method(s) | Mutation analysis; Sequence based prediction; Affinity chromatography technology; Electron microscopy; Pull down; Alanine scanning; Classical fluorescence spectroscopy; structure based prediction; Molecular sieving; NMR |
Interaction ID | 20106 |
Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 |
Disease Association(s) | Unknown |
Inhibitor(s) | Unknown |
Reference(s) | 10556052, 15674283, 20538977 |
Comments | WH2 motif (400-417) in Drosophila protein Spire that binds to the hydrophobic cleft formed by subdomains 1 and 3 of Acanthamoeba Actin-1 |