Instance ID10111
Regular Expression[^R]xx((x[ILMVF])|([ILMVF]x))[^P][^P][ILVM]x{4,7}L(([KR]x)|(NK))[VATIGS]
Motif InstanceGEDMLNAIRRGVKLKKT
Bait Uniprot AccessionO43312
Bait Uniprot IdentifierMTSS1_HUMAN
Bait Gene NameMTSS1
Bait OrganismHomo sapiens (Human)
Sequence Position728-744
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Structure based prediction; ITC; Sequence based prediction; X-ray crystallography
Interaction ID20111
Interacting DomainHydrophobic cleft formed by subdomains 1 and 3
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)17292833, 16275905
CommentsThe WH2 motif in human Metastasis suppressor protein 1 that mediates its interaction with the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)