Instance ID10115
Regular ExpressionFxx[FWY][ST][FY]
Motif InstanceFRGFSF
Bait Uniprot AccessionP18654
Bait Uniprot IdentifierKS6A3_MOUSE
Bait Gene NameRps6ka3
Bait OrganismMus musculus (Mouse)
Sequence Position382-387
Critical ResiduesP5
Motif PTM(s)Phosphorylation at Ser-P5
Secondary StructureUnknown
Experimental Method(s)Protein kinase assay; Co-IP; Mutation analysis
Interaction ID20115
Interacting DomainPIF-binding pocket
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10856237
CommentsHydrophobic motif of the 90 kDa ribosomal S6 kinase-2 (RSK2), a growth factor-stimulated protein kinase, that acts as a phosphorylation-dependent docking site and activator of PDK1

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)