Instance ID10118
Regular ExpressionFxx[FWY][ST][FY]
Motif InstanceFVGFSY
Bait Uniprot AccessionQ96BR1
Bait Uniprot IdentifierSGK3_HUMAN
Bait Gene NameSGK3
Bait OrganismHomo sapiens (Human)
Sequence Position482-487
Critical ResiduesP5
Motif PTM(s)Phosphorylation at Ser-P5
Secondary StructureUnknown
Experimental Method(s)Protein kinase assay; Co-IP; Mutation analysis
Interaction ID20118
Interacting DomainPIF-binding pocket
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16790420
CommentsPhosphorylation of the hydrophobic motif of Serine/threonine-protein kinase Sgk3 promotes its interaction with the PIF-binding pocket of PDK1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)