Instance ID10122
Regular ExpressionFxx[FWY][DE][FY]
Motif InstanceFEGFEY
Bait Uniprot AccessionP41743
Bait Uniprot IdentifierKPCI_HUMAN
Bait Gene NamePRKCI
Bait OrganismHomo sapiens (Human)
Sequence Position579-584
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Y2H; Pull down; Mutation analysis
Interaction ID20122
Interacting DomainPIF-binding pocket
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10764742
Comments"The hydrophobic motif in PKCiota that acts as a ""docking site"" for the recruitment of PDK1 resulting in phosphorylation at its T-loop site by PDK1 in cells"

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)