Instance ID10124
Regular ExpressionFxx[FWY][DE][FY]
Motif InstanceFEGFEY
Bait Uniprot AccessionQ02956
Bait Uniprot IdentifierKPCZ_MOUSE
Bait Gene NamePrkcz
Bait OrganismMus musculus (Mouse)
Sequence Position575-580
Critical ResiduesP1; P4; P6
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down; Competition binding; Mutation analysis
Interaction ID20124
Interacting DomainPIF-binding pocket
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10764742
Comments"The hydrophobic motif in mouse PKCzeta that acts as a ""docking site"" for the recruitment of PDK1 resulting in phosphorylation at its T-loop site by PDK1 in cells"

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)