Instance ID10125
Regular ExpressionFxx[FWY][DE][FY]
Motif InstanceFLDFDF
Bait Uniprot AccessionQ16512
Bait Uniprot IdentifierPKN1_HUMAN
Bait Gene NamePKN1
Bait OrganismHomo sapiens (Human)
Sequence Position932-937
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Y2H; Pull down; Mutation analysis
Interaction ID20125
Interacting DomainPIF-binding pocket
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10764742
Comments"The hydrophobic motif in the PKC-related kinase, PRK1 (or PKN1), which acts as a ""docking site"" for recruitment of PDK1 and is essential for its phosphorylation by PDK1 in cells"


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)