Instance ID10129
Regular ExpressionFxxF$
Motif InstanceFTEF
Bait Uniprot AccessionP05132
Bait Uniprot IdentifierKAPCA_MOUSE
Bait Gene NamePrkaca
Bait OrganismMus musculus (Mouse)
Sequence Position348-351
Critical ResiduesP1; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)X-ray crystallography; Protein kinase assay; Mutation analysis
Interaction ID20129
Interacting DomainPIF-binding pocket
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15299527, 12372837
Comments"The C-terminal hydrophobic motif in cAMP-dependent protein kinase catalytic subunit alpha which acts as a ""docking site"" for its phosphorylation by Phosphoinositide-dependent kinase-1 (PDK-1)"

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)