Instance ID10131
Regular ExpressionFxDxF
Motif InstanceFGDAF
Bait Uniprot AccessionQ61548
Bait Uniprot IdentifierAP180_MOUSE
Bait Gene NameSnap91
Bait OrganismMus musculus (Mouse)
Sequence Position640-644
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Western blot; Co-IP; Pull down(GST tag)
Interaction ID20131
Interacting DomainC-terminal appendage domain of AP-2 subunit alpha-2
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10428863, 12057195
CommentsThe FxDxF motif responsible for the binding of mouse Clathrin coat assembly protein AP180 to the alpha-subunit of adaptor protein AP-2 and its recruitment to the site of clathrin coated vesicle formation

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)