Instance ID10157
Regular ExpressionxRxxLxx[LIVM]x
Motif InstanceNRKPLTVLN
Bait Uniprot AccessionP53350
Bait Uniprot IdentifierPLK1_HUMAN
Bait Gene NamePLK1
Bait OrganismHomo sapiens (Human)
Sequence Position336-344
Critical ResiduesP2; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis
Interaction ID20157
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)14734534
CommentsAPCC-binding Destruction motif (DBox) in human Polo-like kinase 1 (PLK1) recognised by Cdh1, co-activator protein for the anaphase-promoting ubiquitin ligase complex APC/C

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)